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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridoxal
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Accession:CHEBI:17310 term browser browse the term
Definition:A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.
Synonyms:exact_synonym: 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde
 related_synonym: 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE;   Formula=C8H9NO3;   InChI=1S/C8H9NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,4,10,12H,3H2,1H3;   InChIKey=RADKZDMFGJYCBB-UHFFFAOYSA-N;   SMILES=[H]C(=O)c1c(CO)cnc(C)c1O;   pyridoxaldehyde
 alt_id: CHEBI:14976;   CHEBI:26423;   CHEBI:45112;   CHEBI:8667
 xref: Beilstein:383768 "Beilstein";   CAS:66-72-8 "ChemIDplus";   CAS:66-72-8 "KEGG COMPOUND";   DrugBank:DB00147;   Drug_Central:4134 "DrugCentral";   Gmelin:218674 "Gmelin";   HMDB:HMDB0001545;   KEGG:C00250;   KNApSAcK:C00007509
 xref_mesh: MESH:D011730
 xref: MetaCyc:PYRIDOXAL;   PDBeChem:PXL;   PMID:17765195 "Europe PMC";   PMID:20381632 "Europe PMC";   PMID:22770225 "Europe PMC";   PMID:23801094 "Europe PMC";   PMID:24365359 "Europe PMC";   Reaxys:383768 "Reaxys";   Wikipedia:Pyridoxal
 cyclic_relationship: is_conjugate_base_of CHEBI:131530


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pyridoxal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdxk pyridoxal kinase JBrowse link 20 10,930,651 10,952,194 RGD:6480464
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:6480464
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:6480464
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
pyridoxal 5'-phosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Fut8 fucosyltransferase 8 JBrowse link 6 100,305,957 100,537,208 RGD:6480464
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:6480464
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:6480464
G Pdxk pyridoxal kinase JBrowse link 20 10,930,651 10,952,194 RGD:6480464
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        biochemical role 19147
          cofactor 15859
            pyridoxal 18
              N(2)-(5'-phosphopyridoxyl)-L-lysine 0
              N(6)-(pyridoxal phosphate)-L-lysine 0
              N(6)-acetyl-N(2)-(5'-phosphopyridoxyl)-L-lysine 0
              N-(5'-phosphopyridoxyl)-D-alanine 0
              N-(5'-phosphopyridoxyl)-L-alanine 0
              pyridoxal 5'-phosphate + 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            formyl group 7681
                                              aldehyde 7681
                                                heteroarenecarbaldehyde 18
                                                  pyridinecarbaldehyde 18
                                                    pyridoxal 18
                                                      N(2)-(5'-phosphopyridoxyl)-L-lysine 0
                                                      N(6)-(pyridoxal phosphate)-L-lysine 0
                                                      N(6)-acetyl-N(2)-(5'-phosphopyridoxyl)-L-lysine 0
                                                      N-(5'-phosphopyridoxyl)-D-alanine 0
                                                      N-(5'-phosphopyridoxyl)-L-alanine 0
                                                      pyridoxal 5'-phosphate + 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.