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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:PD-146176
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Accession:CHEBI:173098 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits.
Synonyms:exact_synonym: 6,11-dihydrothiochromeno[4,3-b]indole
 related_synonym: 6,11-dihydro[1]benzothiopyrano[4,3-b]indole;   Formula=C15H11NS;   InChI=1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2;   InChIKey=ZGOOPZVQMLHPFM-UHFFFAOYSA-N;   PD146176;   SMILES=C1SC2=CC=CC=C2C2=C1C1=C(N2)C=CC=C1
 xref: CAS:4079-26-9;   PMID:15713402;   PMID:17378609;   PMID:21619415;   PMID:23382512;   PMID:25560760;   PMID:26040494;   PMID:26331552;   PMID:27477687;   PMID:27499089;   PMID:29546268;   PMID:30964295;   PMID:32945449;   PMID:9105693;   PMID:9543090



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Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      biological role 25935
        inhibitor 22527
          ferroptosis inhibitor 7910
            PD-146176 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            organic molecule 25228
                              organic cyclic compound 24279
                                organic heterocyclic compound 22322
                                  organic heteropolycyclic compound 21309
                                    organic heterotetracyclic compound 10072
                                      PD-146176 0
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