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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:PD-146176
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Accession:CHEBI:173098 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits.
Synonyms:exact_synonym: 6,11-dihydrothiochromeno[4,3-b]indole
 related_synonym: 6,11-dihydro[1]benzothiopyrano[4,3-b]indole;   Formula=C15H11NS;   InChI=1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2;   InChIKey=ZGOOPZVQMLHPFM-UHFFFAOYSA-N;   PD146176;   SMILES=C1SC2=CC=CC=C2C2=C1C1=C(N2)C=CC=C1
 xref: CAS:4079-26-9;   PMID:15713402;   PMID:17378609;   PMID:21619415;   PMID:23382512;   PMID:25560760;   PMID:26040494;   PMID:26331552;   PMID:27477687;   PMID:27499089;   PMID:29546268;   PMID:30964295;   PMID:32945449;   PMID:9105693;   PMID:9543090



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Path 1
Term Annotations click to browse term
  CHEBI ontology 19863
    role 19835
      biological role 19833
        inhibitor 18908
          ferroptosis inhibitor 8109
            PD-146176 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19863
    subatomic particle 19861
      composite particle 19861
        hadron 19861
          baryon 19861
            nucleon 19861
              atomic nucleus 19861
                atom 19861
                  main group element atom 19807
                    p-block element atom 19807
                      carbon group element atom 19748
                        carbon atom 19744
                          organic molecular entity 19744
                            organic molecule 19695
                              organic cyclic compound 19506
                                organic heterocyclic compound 18878
                                  organic heteropolycyclic compound 18304
                                    organic heterotetracyclic compound 9217
                                      PD-146176 0
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