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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:estrone
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Accession:CHEBI:17263 term browser browse the term
Definition:A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17.
Synonyms:exact_synonym: 3-hydroxyestra-1,3,5(10)-trien-17-one
 related_synonym: 3-Hydroxy-1,3,5(10)-estratrien-17-one;   Formula=C18H22O2;   InChI=1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1;   InChIKey=DNXHEGUUPJUMQT-CBZIJGRNSA-N;   SMILES=[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21;   follicular hormone;   folliculin;   oestrone
 alt_id: CHEBI:14220;   CHEBI:23971;   CHEBI:4870
 xref: Beilstein:1915077;   CAS:53-16-7;   DrugBank:DB00655;   Drug_Central:3188;   Gmelin:542591;   HMDB:HMDB0000145;   KEGG:C00468;   KEGG:D00067;   KNApSAcK:C00003663;   LINCS:LSM-3837;   LIPID_MAPS_instance:LMST02010004
 xref_mesh: MESH:D004970
 xref: PDBeChem:J3Z;   PMID:11786692;   PMID:19610377;   PMID:23647561;   PMID:24390165;   PMID:24398390;   Patent:FR1305992;   Patent:US1967350;   Patent:US1967351;   Reaxys:1915077;   Wikipedia:Estrone



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estrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPI alkaline phosphatase, intestinal increases chemical synthesis EXP ALPI protein results in increased chemical synthesis of Estrone CTD PMID:1495895 NCBI chr25:44,107,418...44,110,947 JBrowse link
estrone 3-sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1B3 solute carrier organic anion transporter family member 1B3 increases transport EXP SLCO1B3 protein results in increased transport of estrone sulfate CTD PMID:20079461 NCBI chr27:26,411,008...26,496,174
Ensembl chr27:26,411,010...26,470,989
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 400
    role 402
      application 360
        pharmaceutical 357
          drug 357
            antineoplastic agent 231
              estrone 2
                15alpha-hydroxyestrone 0
                16alpha-hydroxyestrone + 0
                16beta-hydroxyestrone 0
                2-hydroxyestrone + 0
                2-methoxyestrone + 0
                2-methoxyestrone 3-sulfate 0
                4-hydroxyestrone + 0
                4-methoxyestrone + 0
                6alpha-hydroxyestrone 0
                6beta-hydroxyestrone 0
                estrone 3-O-(beta-D-glucuronide) 0
                estrone 3-sulfate 1
                estrone sodium sulfate 0
                estropipate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 400
    subatomic particle 400
      composite particle 402
        hadron 400
          baryon 400
            nucleon 400
              atomic nucleus 400
                atom 400
                  main group element atom 395
                    p-block element atom 395
                      carbon group element atom 382
                        carbon atom 383
                          organic molecular entity 381
                            organic group 311
                              organic divalent group 310
                                organodiyl group 310
                                  carbonyl group 310
                                    carbonyl compound 310
                                      ketone 48
                                        oxo steroid 23
                                          17-oxo steroid 2
                                            estrone 2
                                              15alpha-hydroxyestrone 0
                                              16alpha-hydroxyestrone + 0
                                              16beta-hydroxyestrone 0
                                              2-hydroxyestrone + 0
                                              2-methoxyestrone + 0
                                              2-methoxyestrone 3-sulfate 0
                                              4-hydroxyestrone + 0
                                              4-methoxyestrone + 0
                                              6alpha-hydroxyestrone 0
                                              6beta-hydroxyestrone 0
                                              estrone 3-O-(beta-D-glucuronide) 0
                                              estrone 3-sulfate 1
                                              estrone sodium sulfate 0
                                              estropipate 0
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