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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2'-deoxyadenosine
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Accession:CHEBI:17256 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside having adenine as the nucleobase.
Synonyms:related_synonym: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol;   5-(6-AMINO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL;   9-(2-Deoxy-beta-D-erythro-pentofuranosyl)adenine;   9-(2-deoxy-beta-D-ribofuranosyl)-9H-purin-6-amine;   Deoxyadenosine;   Formula=C10H13N5O3;   InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1;   InChIKey=OLXZPDWKRNYJJZ-RRKCRQDMSA-N;   SMILES=Nc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](CO)O1;   adenine deoxyribonucleoside;   adenyldeoxyriboside;   dA
 alt_id: CHEBI:14112;   CHEBI:19234;   CHEBI:39863;   CHEBI:40535;   CHEBI:40560;   CHEBI:4405
 xref: Beilstein:91015;   CAS:958-09-8;   Gmelin:283189;   HMDB:HMDB0000101;   KEGG:C00559;   KNApSAcK:C00019281
 xref_mesh: MESH:C058118
 xref: MetaCyc:DEOXYADENOSINE;   PDBeChem:3D1;   PMID:14253484;   PMID:18508186;   PMID:24144081;   PMID:8171392;   PMID:9869364;   Reaxys:91015;   Wikipedia:Deoxyadenosine

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2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO 2'-deoxyadenosine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Polb DNA polymerase beta multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLB protein CTD PMID:26098310 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271 		JBrowse link
G Poli DNA polymerase iota multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein; POLN protein inhibits the reaction [[diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein] CTD PMID:26098310 NCBI chr18:65,749,107...65,768,805
Ensembl chr18:65,748,908...65,768,781 		JBrowse link
G Polk DNA polymerase kappa multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLK protein CTD PMID:26098310 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906 		JBrowse link
G Poln DNA polymerase nu multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLN protein; POLN protein inhibits the reaction [[diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein] CTD PMID:26098310 NCBI chr14:81,837,764...82,037,999
Ensembl chr14:81,858,737...82,037,747 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO 2'-deoxyadenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO 2'-deoxyadenosine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:220,306,622...220,314,631
Ensembl chr 1:220,400,855...220,407,189
Ensembl chr 1:220,400,855...220,407,189 		JBrowse link
8,5'-cyclo-2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 affects metabolic processing ISO NEIL1 protein affects the metabolism of 8,5'-cyclo-2'-deoxyadenosine CTD PMID:20067321 NCBI chr 8:61,817,258...61,824,023
Ensembl chr 8:61,817,258...61,823,102 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19841
      atom 19839
        nonmetal atom 19720
          carbon atom 19625
            organic molecular entity 19625
              purines 2'-deoxy-D-ribonucleoside 14
                2'-deoxyadenosine 8
                  8,5'-cyclo-2'-deoxyadenosine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            heteroorganic entity 19217
                              organochalcogen compound 18922
                                organooxygen compound 18846
                                  carbohydrates and carbohydrate derivatives 12248
                                    carbohydrate 12248
                                      carbohydrate derivative 11874
                                        glycosyl compound 10927
                                          N-glycosyl compound 5470
                                            nucleoside 5331
                                              deoxyribonucleoside 2729
                                                2'-deoxyribonucleoside 2213
                                                  purine 2'-deoxyribonucleoside 33
                                                    purines 2'-deoxy-D-ribonucleoside 14
                                                      2'-deoxyadenosine 8
                                                        8,5'-cyclo-2'-deoxyadenosine 1
paths to the root