mono(2-ethylhexyl) phthalate - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	mono(2-ethylhexyl) phthalate	go back to main search page
Accession:	CHEBI:17243	browse the term
Definition:	The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Synonyms:	exact_synonym:	2-(2-ethylhexyloxycarbonyl)benzoic acid
	related_synonym:	1,2-benzenedicarboxylic acid, mono(2-ethylhexyl) ester; 2-([(2-ethylhexyl)oxy]carbonyl)benzoic acid; 2-Ethylhexyl phthalate; 2-ethylhexyl hydrogen phthalate; Formula=C16H22O4; InChI=1S/C16H22O4/c1-3-5-8-12(4-2)11-20-16(19)14-10-7-6-9-13(14)15(17)18/h6-7,9-10,12H,3-5,8,11H2,1-2H3,(H,17,18); InChIKey=DJDSLBVSSOQSLW-UHFFFAOYSA-N; MEHP; SMILES=CCCCC(CC)COC(=O)c1ccccc1C(O)=O; monoethylhexyl phthalate; phthalic acid, 2-ethylhexyl ester
	alt_id:	CHEBI:1094; CHEBI:11575
	xref:	Beilstein:3206630; CAS:4376-20-9; KEGG:C03343; LINCS:LSM-36855
	xref_mesh:	MESH:C016599
	cyclic_relationship:	is_conjugate_acid_of CHEBI:58071

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Genes (1991)

mono(2-ethylhexyl) phthalate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 2310011J03 gene

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of C7H19ORF25 mRNA

NCBI chr10:80,154,089...80,156,382
Ensembl chr10:80,154,088...80,156,371

G

alpha-2-macroglobulin

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of A2M mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of A2M mRNA

PMID:36189433 PMID:38113427

NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186

G

adipogenesis associated Mth938 domain containing

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of AAMDC mRNA

NCBI chr 7:97,199,538...97,228,723
Ensembl chr 7:97,199,538...97,228,704

G

ATP-binding cassette, sub-family A member 12

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ABCA12 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ABCA12 mRNA

PMID:22401849 PMID:36189433

NCBI chr 1:71,282,249...71,454,069
Ensembl chr 1:71,281,435...71,454,069

G

ATP-binding cassette, sub-family A member 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ABCA4 mRNA

NCBI chr 3:121,837,547...121,973,719
Ensembl chr 3:121,838,092...121,973,772

G

ATP-binding cassette, sub-family A member 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ABCA7 mRNA

NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406

G

ATP-binding cassette, sub-family B member 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ABCB11 mRNA

NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958

G

ATP-binding cassette, sub-family B member 1B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ABCB1B mRNA

NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315

G

ATP-binding cassette, sub-family B member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ABCB5 mRNA

NCBI chr12:118,831,221...118,930,169
Ensembl chr12:118,831,559...118,930,156

G

ATP-binding cassette, sub-family B member 9

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ABCB9 mRNA

NCBI chr 5:124,199,920...124,234,009
Ensembl chr 5:124,199,593...124,233,861

G

ATP-binding cassette, sub-family C member 10

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ABCC10 mRNA

NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278

G

ATP-binding cassette, sub-family member 2

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of ABCC2 mRNA

NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179

G

ATP-binding cassette, sub-family C member 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ABCC6 mRNA

NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726

G

actin-binding LIM protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ABLIM2 mRNA

NCBI chr 5:35,915,200...36,042,323
Ensembl chr 5:35,915,224...36,042,317

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACAA1B mRNA

NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161

G

acetyl-CoA acyltransferase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACAA2 mRNA

NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279

G

acyl-Coenzyme A dehydrogenase, medium chain

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACADM mRNA

NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269

G

acyl-Coenzyme A dehydrogenase, short chain

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACADS mRNA

NCBI chr 5:115,248,358...115,257,405
Ensembl chr 5:115,248,358...115,257,405

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACAP1 mRNA

NCBI chr11:69,772,393...69,786,390
Ensembl chr11:69,772,393...69,786,365

G

angiotensin converting enzyme 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ACE2 mRNA

NCBI chr X:162,922,338...162,971,414
Ensembl chr X:162,922,328...162,971,416

G

atypical chemokine receptor 1 (Duffy blood group)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ACKR1 mRNA

NCBI chr 1:173,159,457...173,161,079
Ensembl chr 1:173,159,453...173,161,317

G

atypical chemokine receptor 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ACKR3 mRNA

NCBI chr 1:90,131,702...90,143,446
Ensembl chr 1:90,131,702...90,144,473

G

atypical chemokine receptor 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ACKR4 mRNA

NCBI chr 9:103,974,881...104,003,842
Ensembl chr 9:103,961,356...104,004,132

G

acyl-Coenzyme A oxidase 1, palmitoyl

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACOX1 mRNA

PMID:22087261 PMID:32522588

NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871

G

acyl-Coenzyme A oxidase-like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ACOXL mRNA

NCBI chr 2:127,680,717...127,968,172
Ensembl chr 2:127,680,796...127,965,793

G

acid phosphatase 5, tartrate resistant

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ACP5 mRNA

NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007

G

acid phosphatase 7, tartrate resistant

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ACP7 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ACP7 mRNA

NCBI chr 7:28,304,055...28,330,755
Ensembl chr 7:28,306,701...28,330,757

G

acyl-CoA synthetase long-chain family member 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ACSL1 protein

NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088

G

acyl-CoA synthetase long-chain family member 4

decreases expression
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ACSL4 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein
ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein]

PMID:22401849 PMID:34863575

NCBI chr X:141,100,989...141,173,792
Ensembl chr X:141,100,989...141,173,531

G

acyl-CoA synthetase short-chain family member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ACSS2 mRNA

NCBI chr 2:155,359,963...155,404,663
Ensembl chr 2:155,359,868...155,427,644

G

actinin alpha 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ACTN2 mRNA

NCBI chr13:12,284,312...12,355,613
Ensembl chr13:12,284,312...12,355,641

G

activin A receptor, type II-like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ACVRL1 mRNA

NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217

G

a disintegrin and metallopeptidase domain 22

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADAM22 mRNA

NCBI chr 5:8,122,353...8,418,312
Ensembl chr 5:8,122,352...8,418,160

G

a disintegrin and metallopeptidase domain 23

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADAM23 mRNA

NCBI chr 1:63,484,880...63,635,263
Ensembl chr 1:63,485,050...63,635,435

G

a disintegrin and metallopeptidase domain 33

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADAM33 mRNA

NCBI chr 2:130,892,739...130,905,734
Ensembl chr 2:130,892,511...130,905,734

G

ADAM metallopeptidase with thrombospondin type 1 motif 14

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADAMTS14 mRNA

NCBI chr10:61,032,886...61,109,447
Ensembl chr10:61,032,891...61,109,217

G

ADAM metallopeptidase with thrombospondin type 1 motif 15

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADAMTS15 mRNA

NCBI chr 9:30,810,451...30,833,853
Ensembl chr 9:30,810,451...30,833,748

G

ADAM metallopeptidase with thrombospondin type 1 motif 17

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ADAMTS17 mRNA

NCBI chr 7:66,487,387...66,802,373
Ensembl chr 7:66,489,483...66,802,919

G

ADAM metallopeptidase with thrombospondin type 1 motif 18

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADAMTS18 mRNA

NCBI chr 8:114,423,755...114,575,975
Ensembl chr 8:114,423,758...114,575,370

G

ADAM metallopeptidase with thrombospondin type 1 motif 20

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ADAMTS20 mRNA

NCBI chr15:94,166,177...94,329,966
Ensembl chr15:94,168,044...94,363,299

G

ADAM metallopeptidase with thrombospondin type 1 motif 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADAMTS4 mRNA

NCBI chr 1:171,077,698...171,089,836
Ensembl chr 1:171,077,990...171,088,206

G

ADAM metallopeptidase with thrombospondin type 1 motif 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ADAMTS5 mRNA

NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716

G

ADAM metallopeptidase with thrombospondin type 1 motif 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ADAMTS6 mRNA

NCBI chr13:104,423,026...104,633,203
Ensembl chr13:104,424,343...104,633,203

G

ADAMTS-like 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADAMTSL4 mRNA

NCBI chr 3:95,583,511...95,595,232
Ensembl chr 3:95,583,511...95,595,228

G

adenosine deaminase, RNA-specific, B2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADARB2 mRNA

NCBI chr13:8,252,475...8,818,798
Ensembl chr13:8,252,902...8,818,783

G

adenylate cyclase 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADCY4 mRNA

NCBI chr14:56,006,513...56,021,552
Ensembl chr14:56,006,514...56,021,552

G

adenylate cyclase 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADCY7 mRNA

NCBI chr 8:88,998,818...89,056,593
Ensembl chr 8:88,999,031...89,056,590

G

adhesion G protein-coupled receptor D1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ADGRD1 mRNA

NCBI chr 5:129,173,741...129,281,663
Ensembl chr 5:129,173,814...129,281,663

G

adhesion G protein-coupled receptor E4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADGRE4 mRNA

NCBI chr17:56,056,984...56,160,662
Ensembl chr17:56,056,984...56,160,662

G

adhesion G protein-coupled receptor F3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADGRF3 mRNA

NCBI chr 5:30,398,429...30,410,752
Ensembl chr 5:30,398,429...30,410,720

G

adhesion G protein-coupled receptor G1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ADGRG1 mRNA

NCBI chr 8:95,701,321...95,740,836
Ensembl chr 8:95,701,379...95,740,845

G

adhesion G protein-coupled receptor G2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADGRG2 mRNA

NCBI chr X:159,173,315...159,281,072
Ensembl chr X:159,173,686...159,281,066

G

adhesion G protein-coupled receptor G6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADGRG6 mRNA

NCBI chr10:14,278,327...14,421,467
Ensembl chr10:14,278,327...14,421,403

G

adiponectin, C1Q and collagen domain containing

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ADIPOQ protein

NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778

G

adiponectin receptor 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ADIPOR2 mRNA

NCBI chr 6:119,330,111...119,394,489
Ensembl chr 6:119,330,111...119,394,665

G

adrenomedullin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADM mRNA

NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027

G

adrenomedullin 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ADM2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADM2 mRNA

PMID:36189433 PMID:36695872

NCBI chr15:89,206,923...89,208,934
Ensembl chr15:89,206,923...89,208,934

G

adenosine A1 receptor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADORA1 mRNA

NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,963...134,163,169

G

adrenergic receptor, alpha 1a

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADRA1A mRNA

NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617

G

adrenergic receptor, alpha 1b

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ADRA1B mRNA

NCBI chr11:43,665,432...43,792,076
Ensembl chr11:43,665,433...43,792,037

G

adrenergic receptor, alpha 1d

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ADRA1D mRNA

NCBI chr 2:131,387,277...131,404,417
Ensembl chr 2:131,387,770...131,404,203

G

afamin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AFM mRNA

NCBI chr 5:90,666,808...90,701,403
Ensembl chr 5:90,666,791...90,701,402

G

alpha fetoprotein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of AFP mRNA

NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766

G

ATP/GTP binding protein-like 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AGBL3 mRNA

NCBI chr 6:34,755,249...34,837,874
Ensembl chr 6:34,757,367...34,836,394

G

amylo-1,6-glucosidase, 4-alpha-glucanotransferase

multiple interactions

mono-(2-ethylhexyl)phthalate binds to and affects the activity of AGL protein

NCBI chr 3:116,533,648...116,601,815
Ensembl chr 3:116,533,648...116,601,815

G

agmatinase

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AGMAT mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of AGMAT mRNA

NCBI chr 4:141,473,986...141,486,574
Ensembl chr 4:141,473,983...141,486,574

G

angiotensinogen

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AGT mRNA

NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445

G

angiotensin II receptor, type 1a

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AGTR1A mRNA

NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850

G

angiotensin II receptor, type 1b

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of AGTR1B mRNA

NCBI chr 3:20,368,637...20,421,341
Ensembl chr 3:20,368,637...20,421,341

G

S-adenosylhomocysteine hydrolase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of AHCY mRNA

NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417

G

aryl-hydrocarbon receptor

increases expression
affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of AHR mRNA
mono-(2-ethylhexyl)phthalate affects the expression of AHR mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHR mRNA

PMID:12706301 PMID:28381288 PMID:31884101

NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037

G

aryl-hydrocarbon receptor repressor

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of AHRR mRNA

NCBI chr13:74,359,237...74,440,450
Ensembl chr13:74,359,237...74,440,450

G

alpha-2-HS-glycoprotein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AHSG protein

NCBI chr16:22,710,793...22,718,193
Ensembl chr16:22,710,027...22,718,199

G

apoptosis-inducing factor, mitochondrion-associated 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of AIFM1 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of AIFM1 mRNA; Estradiol affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of AIFM1 mRNA]

PMID:24412242 PMID:31884101

NCBI chr X:47,563,821...47,602,440
Ensembl chr X:47,563,821...47,602,440

G

apoptosis-inducing factor, mitochondrion-associated 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AIFM3 mRNA

NCBI chr16:17,307,418...17,325,349
Ensembl chr16:17,307,475...17,325,349

G

ajuba LIM protein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AJUBA mRNA

NCBI chr14:54,804,926...54,815,118
Ensembl chr14:54,804,929...54,815,015

G

adenylate kinase 5

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AK5 mRNA

NCBI chr 3:152,168,461...152,373,992
Ensembl chr 3:152,168,452...152,373,997

G

adenylate kinase 7

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AK7 mRNA

NCBI chr12:105,670,115...105,748,706
Ensembl chr12:105,672,235...105,748,706

G

A kinase anchor protein 4

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of AKAP4 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of AKAP4 mRNA

NCBI chr X:6,933,754...6,944,848
Ensembl chr X:6,933,758...6,944,848

G

alkaline phosphatase 3, intestine, not Mn requiring

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ALPP mRNA

NCBI chr 1:87,052,676...87,056,450
Ensembl chr 1:87,052,695...87,055,634

G

thymoma viral proto-oncogene 1

multiple interactions
affects response to substance
increases activity
increases phosphorylation

AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA]; AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 protein]; AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFKB1 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased expression of and results in increased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to mono-(2-ethylhexyl)phthalate
mono-(2-ethylhexyl)phthalate results in increased activity of AKT1 protein
mono-(2-ethylhexyl)phthalate results in increased phosphorylation of AKT1 protein
mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of AKT1 protein; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of AKT1 protein]

PMID:18755736 PMID:28526321 PMID:31009676 PMID:34910997

NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318

G

AKT1 substrate 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of AKT1S1 mRNA

NCBI chr 7:44,498,648...44,504,845
Ensembl chr 7:44,498,415...44,504,845

G

aldehyde dehydrogenase family 1, subfamily A1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ALDH1A1 mRNA

NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829

G

aldehyde dehydrogenase 2, mitochondrial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ALDH2 mRNA

NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887

G

alkB homolog 5, RNA demethylase

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ALKBH5 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of ALKBH5 mRNA

PMID:36174712 PMID:36314267

NCBI chr11:60,428,509...60,449,338
Ensembl chr11:60,427,207...60,449,338

G

alkaline phosphatase, liver/bone/kidney

decreases expression

mono-(2-ethylhexyl)phthalate analog results in decreased expression of ALPL protein; mono-(2-ethylhexyl)phthalate results in decreased expression of ALPL protein

NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695

G

alkaline phosphatase, placental-like 2

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ALPPL2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of ALPPL2 mRNA

NCBI chr 1:87,014,412...87,023,656
Ensembl chr 1:87,014,416...87,017,650

G

aristaless-like homeobox 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ALX4 mRNA

NCBI chr 2:93,472,779...93,511,686
Ensembl chr 2:93,472,729...93,511,684

G

anti-Mullerian hormone

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of AMH mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of AMH protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of AMH mRNA

PMID:19165384 PMID:19440488 PMID:36189433

NCBI chr10:80,641,074...80,643,513
Ensembl chr10:80,641,077...80,643,482

G

adhesion molecule with Ig like domain 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AMIGO2 mRNA

NCBI chr15:97,141,955...97,145,168
Ensembl chr15:97,142,006...97,145,168

G

angiogenin, ribonuclease, RNase A family, 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ANG mRNA

NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466

G

angiopoietin 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ANGPT4 mRNA

NCBI chr 2:151,753,127...151,787,257
Ensembl chr 2:151,753,130...151,787,257

G

angiopoietin-like 4

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ANGPTL4 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased methylation of ANGPTL4 mRNA

PMID:36189433 PMID:36314267 PMID:36695872

NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804

G

angiopoietin-like 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ANGPTL8 mRNA

NCBI chr 9:21,746,806...21,748,643
Ensembl chr 9:21,746,806...21,748,643

G

ankyrin 1, erythroid

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ANK1 mRNA

NCBI chr 8:23,464,852...23,640,517
Ensembl chr 8:23,464,860...23,640,513

G

ankyrin 2, brain

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ANK2 mRNA

NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999

G

ankyrin 3, epithelial

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ANK3 mRNA

NCBI chr10:69,234,608...69,863,266
Ensembl chr10:69,234,603...69,863,268

G

ankyrin repeat domain 34B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ANKRD34B mRNA

NCBI chr13:92,562,413...92,578,166
Ensembl chr13:92,562,404...92,578,166

G

ankyrin repeat domain 37

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ANKRD37 mRNA

NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744

G

ankyrin repeat domain 63

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ANKRD63 mRNA

NCBI chr 2:118,529,584...118,534,444
Ensembl chr 2:118,529,584...118,534,444

G

anoctamin 9

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ANO9 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ANO9 mRNA

PMID:22401849 PMID:36189433

NCBI chr 7:140,681,125...140,697,719
Ensembl chr 7:140,681,125...140,697,719

G

anthrax toxin receptor 2

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ANTXR2 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of ANTXR2 mRNA

PMID:22401849 PMID:36695872

NCBI chr 5:98,032,547...98,178,876
Ensembl chr 5:98,030,642...98,178,902

G

annexin A2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ANXA2 mRNA

NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077

G

annexin A9

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ANXA9 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ANXA9 mRNA

PMID:36189433 PMID:36695872

NCBI chr 3:95,203,404...95,222,491
Ensembl chr 3:95,203,407...95,214,487

G

aldehyde oxidase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of AOX1 mRNA

NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572

G

amyloid beta precursor protein binding family A member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of APBA2 mRNA

NCBI chr 7:64,151,444...64,403,620
Ensembl chr 7:64,151,454...64,403,626

G

APC, WNT signaling pathway regulator

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of APC mRNA

NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605

G

apelin

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of APLN mRNA

NCBI chr X:47,114,023...47,123,730
Ensembl chr X:47,114,023...47,123,730

G

apolipoprotein E

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of APOE mRNA

NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113

G

aquaporin 12

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of AQP12 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of AQP12 mRNA

NCBI chr 1:92,934,056...92,939,991
Ensembl chr 1:92,934,056...92,939,991

G

androgen receptor

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [cyclopamine results in increased expression of AR]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of AR mRNA

PMID:26710974 PMID:31884101

NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821

G

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ARAP2 mRNA

NCBI chr 5:62,759,788...62,923,874
Ensembl chr 5:62,759,788...62,923,502

G

Rho GTPase activating protein 27

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ARHGAP27 mRNA

NCBI chr11:103,222,310...103,254,518
Ensembl chr11:103,222,323...103,254,518

G

Rho GTPase activating protein 28

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ARHGAP28 mRNA

NCBI chr17:68,149,701...68,311,185
Ensembl chr17:68,149,708...68,311,115

G

Rho GTPase activating protein 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ARHGAP9 mRNA

NCBI chr10:127,157,829...127,165,816
Ensembl chr10:127,157,833...127,165,812

G

Rho guanine nucleotide exchange factor 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ARHGEF4 mRNA

NCBI chr 1:34,717,263...34,851,819
Ensembl chr 1:34,717,269...34,852,390

G

ADP-ribosylation factor-like 4D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ARL4D mRNA

NCBI chr11:101,556,367...101,558,658
Ensembl chr11:101,556,367...101,558,658

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions
increases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ARNT mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of ARNT mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of ARNT protein

PMID:31884101 PMID:34863575

NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551

G

arrestin, beta 2

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of ARRB2 protein]

NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654

G

arrestin domain containing 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ARRDC3 mRNA

NCBI chr13:81,031,508...81,044,161
Ensembl chr13:81,031,503...81,044,161

G

artemin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ARTN mRNA

NCBI chr 4:117,783,105...117,787,993
Ensembl chr 4:117,783,359...117,786,960

G

ankyrin repeat and SOCS box-containing 14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ASB14 mRNA

NCBI chr14:26,616,547...26,638,393
Ensembl chr14:26,616,514...26,637,215

G

activating signal cointegrator 1 complex subunit 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ASCC3 mRNA

NCBI chr10:50,468,756...50,727,300
Ensembl chr10:50,468,765...50,727,581

G

asialoglycoprotein receptor 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ASGR1 mRNA

NCBI chr11:69,939,735...69,948,721
Ensembl chr11:69,944,911...69,948,720

G

acid-sensing ion channel family member 4

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ASIC4 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of ASIC4 mRNA

NCBI chr 1:75,426,467...75,450,984
Ensembl chr 1:75,427,080...75,450,987

G

asparagine synthetase

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ASNS mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ASNS mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254

G

asporin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ASPN mRNA

NCBI chr13:49,697,919...49,721,041
Ensembl chr13:49,697,919...49,721,041

G

argininosuccinate synthetase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ASS1 mRNA

NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684

G

astrotactin 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ASTN1 mRNA

NCBI chr 1:158,189,647...158,519,351
Ensembl chr 1:158,189,843...158,519,351

G

activating transcription factor 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ATF3 mRNA

NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236

G

activating transcription factor 6

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ATF6 protein]

NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340

G

activating transcription factor 7 interacting protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ATF7IP2 mRNA

NCBI chr16:10,010,513...10,068,595
Ensembl chr16:10,010,576...10,069,342

G

atonal bHLH transcription factor 8

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ATOH8 mRNA

NCBI chr 6:72,183,158...72,212,765
Ensembl chr 6:72,183,161...72,212,561

G

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ATP12A mRNA

NCBI chr14:56,602,525...56,626,008
Ensembl chr14:56,602,525...56,626,007

G

ATPase type 13A4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ATP13A4 mRNA

NCBI chr16:29,208,685...29,363,682
Ensembl chr16:29,214,671...29,363,682

G

ATPase, Na+/K+ transporting, alpha 3 polypeptide

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ATP1A3 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of ATP1A3 mRNA

PMID:22401849 PMID:37364752

NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383

G

ATPase, H+ transporting, lysosomal V0 subunit A4

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ATP6V0A4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ATP6V0A4 mRNA

NCBI chr 6:38,025,418...38,101,521
Ensembl chr 6:38,025,418...38,101,521

G

ATPase, H+ transporting, lysosomal V1 subunit C2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ATP6V1C2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ATP6V1C2 mRNA

PMID:22401849 PMID:36189433

NCBI chr12:17,334,722...17,375,700
Ensembl chr12:17,334,722...17,379,360

G

ATPase, H+ transporting, lysosomal V1 subunit H

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of ATP6V1H mRNA

NCBI chr 1:5,153,201...5,233,438
Ensembl chr 1:5,140,241...5,232,752

G

ATPase, class I, type 8B, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ATP8B1 mRNA

NCBI chr18:64,662,050...64,794,342
Ensembl chr18:64,662,038...64,794,338

G

ATPase, class I, type 8B, member 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ATP8B4 mRNA

NCBI chr 2:126,162,893...126,342,589
Ensembl chr 2:126,162,893...126,342,594

G

ATPase, class II, type 9B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ATP9B mRNA

NCBI chr18:80,777,356...80,977,291
Ensembl chr18:80,777,356...80,977,275

G

attractin like 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ATRNL1 mRNA

NCBI chr19:57,599,248...58,121,775
Ensembl chr19:57,599,466...58,121,775

G

aurora kinase C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AURKC mRNA

NCBI chr 7:6,998,346...7,006,090
Ensembl chr 7:6,998,299...7,006,090

G

arginine vasopressin-induced 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of AVPI1 mRNA

NCBI chr19:42,111,714...42,117,432
Ensembl chr19:42,111,712...42,117,498

G

arginine vasopressin receptor 1A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AVPR1A mRNA

NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357

G

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of B3GALT1 mRNA

NCBI chr 2:67,395,528...67,953,226
Ensembl chr 2:67,396,215...67,953,033

G

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of B3GALT2 mRNA

PMID:22401849 PMID:36695872

NCBI chr 1:143,516,435...143,525,675
Ensembl chr 1:143,516,402...143,530,352

G

beta-1,3-glucuronyltransferase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of B3GAT1 mRNA

NCBI chr 9:26,644,813...26,672,646
Ensembl chr 9:26,645,024...26,674,397

G

beta-1,4-N-acetyl-galactosaminyl transferase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of B4GALNT3 mRNA

NCBI chr 6:120,177,714...120,271,879
Ensembl chr 6:120,180,034...120,271,520

G

beta-site APP-cleaving enzyme 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BACE2 mRNA

NCBI chr16:97,157,928...97,244,136
Ensembl chr16:97,157,942...97,244,136

G

BAI1-associated protein 2-like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of BAIAP2L1 mRNA

NCBI chr 5:144,201,335...144,294,922
Ensembl chr 5:144,201,336...144,294,922

G

BarH like homeobox 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BARHL2 mRNA

NCBI chr 5:106,600,389...106,606,032
Ensembl chr 5:106,600,389...106,606,032

G

BCL2-associated X protein

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of BAX mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of BAX protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BAX protein]; GW 6471 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BAX protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BAX mRNA
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BAX mRNA]

PMID:12927354 PMID:24706461 PMID:26597031 PMID:31884101 PMID:33159713 More...

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

bromodomain adjacent to zinc finger domain 1A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BAZ1A mRNA

NCBI chr12:54,939,774...55,061,155
Ensembl chr12:54,940,336...55,061,133

G

BCL2 binding component 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of BBC3 protein

NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130

G

brevican

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BCAN mRNA

NCBI chr 3:87,894,839...87,908,458
Ensembl chr 3:87,894,838...87,907,537

G

B cell leukemia/lymphoma 2

decreases expression
multiple interactions
affects expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 protein
[mono-(2-ethylhexyl)phthalate co-treated with Estradiol] results in decreased expression of BCL2 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of BCL2 mRNA; epigallocatechin gallate affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of BCL2 protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BCL2 mRNA; MIR16-1 mRNA affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 protein]

PMID:12927354 PMID:24412242 PMID:24706461 PMID:26597031 PMID:31884101 More...

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2-like 1

multiple interactions
increases expression

AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA]; AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 protein

NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648

G

Bcl2-like 10

multiple interactions
decreases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BCL2L10 mRNA; Estradiol affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2L10 mRNA]

PMID:24412242 PMID:31884101

NCBI chr 9:75,255,040...75,258,922
Ensembl chr 9:75,255,040...75,258,931

G

BCL2 like 11

multiple interactions
increases expression

GW 6471 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L11 protein]

NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467

G

B cell leukemia/lymphoma 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of BCL6 mRNA

NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602

G

brain derived neurotrophic factor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BDNF mRNA

NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352

G

brain expressed, associated with Nedd4, 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BEAN1 mRNA

NCBI chr 8:104,897,110...104,945,730
Ensembl chr 8:104,897,074...104,945,754

G

beaded filament structural protein 2, phakinin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BFSP2 mRNA

NCBI chr 9:103,302,123...103,357,608
Ensembl chr 9:103,302,123...103,357,619

G

bone gamma-carboxyglutamate protein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of BGLAP3 mRNA

NCBI chr 3:88,275,923...88,280,048
Ensembl chr 3:88,275,923...88,280,050

G

biglycan

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of BGN mRNA

NCBI chr X:72,527,207...72,539,542
Ensembl chr X:72,527,208...72,539,539

G

betaine-homocysteine methyltransferase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BHMT mRNA

NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469

G

BRD4 interacting chromatin remodeling complex associated protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BICRA mRNA

NCBI chr 7:15,704,596...15,785,047
Ensembl chr 7:15,704,597...15,781,846

G

BH3 interacting domain death agonist

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of BID mRNA

NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814

G

BCL2-interacting killer

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of BIK mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of BIK mRNA

NCBI chr15:83,410,992...83,428,836
Ensembl chr15:83,411,063...83,428,835

G

B lymphoid kinase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BLK mRNA

NCBI chr14:63,610,286...63,654,636
Ensembl chr14:63,610,285...63,654,486

G

B cell linker

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BLNK mRNA

NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978

G

BCL2 modifying factor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BMF mRNA

NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168

G

bone morphogenetic protein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BMP3 mRNA

NCBI chr 5:99,002,274...99,031,912
Ensembl chr 5:99,002,274...99,032,255

G

bone morphogenetic protein 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BMP5 mRNA

NCBI chr 9:75,682,647...75,807,598
Ensembl chr 9:75,682,646...75,807,592

G

bone morphogenetic protein 8b

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Triiodothyronine] results in increased expression of BMP8B mRNA

NCBI chr 4:122,998,101...123,019,887
Ensembl chr 4:122,998,958...123,025,892

G

BMP-binding endothelial regulator

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BMPER mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of BMPER mRNA

NCBI chr 9:23,134,372...23,396,511
Ensembl chr 9:23,134,372...23,396,496

G

BCL2-related ovarian killer

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of BOK mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of BOK mRNA

PMID:24412242 PMID:31884101

NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486

G

BPI fold containing family A, member 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BPIFA6 mRNA

NCBI chr 2:153,816,865...153,842,415
Ensembl chr 2:153,816,865...153,842,415

G

BPI fold containing family B, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BPIFB1 mRNA

NCBI chr 2:154,032,738...154,062,263
Ensembl chr 2:154,032,738...154,062,289

G

BPI fold containing family B, member 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BPIFB6 mRNA

NCBI chr 2:153,742,308...153,754,715
Ensembl chr 2:153,742,308...153,754,715

G

bromodomain containing 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of BRD3 mRNA

NCBI chr 2:27,335,588...27,397,669
Ensembl chr 2:27,335,591...27,397,674

G

bone morphogenetic protein/retinoic acid inducible neural specific 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of BRINP3 mRNA

NCBI chr 1:146,371,367...146,778,210
Ensembl chr 1:146,370,498...146,778,210

G

BR serine/threonine kinase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BRSK1 mRNA

NCBI chr 7:4,693,635...4,718,996
Ensembl chr 7:4,693,603...4,718,996

G

BR serine/threonine kinase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of BRSK2 mRNA

NCBI chr 7:141,503,488...141,557,981
Ensembl chr 7:141,503,488...141,557,984

G

bone marrow stromal cell antigen 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BST2 mRNA

NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100

G

BTG anti-proliferation factor 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of BTG2 mRNA

NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858

G

butyrophilin, subfamily 1, member A1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of BTN1A1 mRNA

NCBI chr13:23,641,154...23,650,084
Ensembl chr13:23,641,162...23,650,071

G

butyrophilin-like 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of BTNL9 mRNA

NCBI chr11:49,059,152...49,077,916
Ensembl chr11:49,056,412...49,077,986

G

blood vessel epicardial substance

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of BVES mRNA

NCBI chr10:45,211,783...45,248,580
Ensembl chr10:45,211,868...45,248,575

G

complement component 1, q subcomponent-like 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of C1QL2 mRNA

NCBI chr 1:120,268,312...120,270,903
Ensembl chr 1:120,268,312...120,270,903

G

C1q and tumor necrosis factor related protein 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of C1QTNF6 mRNA

NCBI chr15:78,407,546...78,416,370
Ensembl chr15:78,407,546...78,415,616

G

complement component 1, r subcomponent B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of C1RB mRNA

NCBI chr 6:124,547,389...124,558,003
Ensembl chr 6:124,547,253...124,558,130

G

complement component 1, s subcomponent 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of C1S2 mRNA

NCBI chr 6:124,601,584...124,613,044
Ensembl chr 6:124,601,584...124,613,044

G

complement C2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of C2 mRNA

NCBI chr17:35,081,578...35,101,076
Ensembl chr17:35,081,580...35,117,241

G

C2 calcium-dependent domain containing 4A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of C2CD4A mRNA

NCBI chr 9:67,737,814...67,739,612
Ensembl chr 9:67,737,771...67,739,612

G

C2 calcium-dependent domain containing 4C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of C2CD4C mRNA

NCBI chr10:79,442,688...79,449,859
Ensembl chr10:79,442,688...79,449,859

G

C2 calcium dependent domain containing 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of C2CD6 mRNA

NCBI chr 1:59,036,275...59,134,283
Ensembl chr 1:59,036,275...59,134,059

G

complement component 8, alpha polypeptide

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of C8A mRNA

NCBI chr 4:104,672,876...104,733,684
Ensembl chr 4:104,672,876...104,733,595

G

CDK5 and Abl enzyme substrate 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CABLES1 mRNA

NCBI chr18:11,972,600...12,078,681
Ensembl chr18:11,972,277...12,078,687

G

calcium binding protein 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CABP1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CABP1 mRNA

PMID:22401849 PMID:36189433

NCBI chr 5:115,306,750...115,332,440
Ensembl chr 5:115,306,748...115,332,440

G

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CACNA1A mRNA

NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875

G

cell adhesion molecule 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CADM1 mRNA

NCBI chr 9:47,441,468...47,773,578
Ensembl chr 9:47,441,471...47,769,413

G

cell adhesion molecule 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CADM3 mRNA

NCBI chr 1:173,161,825...173,195,214
Ensembl chr 1:173,160,825...173,195,261

G

calneuron 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CALN1 mRNA

NCBI chr 5:130,398,245...130,876,253
Ensembl chr 5:130,398,296...130,876,253

G

calcium/calmodulin-dependent protein kinase ID

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CAMK1D mRNA

NCBI chr 2:5,298,268...5,719,665
Ensembl chr 2:5,298,268...5,719,326

G

calcium/calmodulin-dependent protein kinase II, beta

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CAMK2B mRNA

NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CAMK2N1 mRNA

NCBI chr 4:138,182,459...138,187,437
Ensembl chr 4:138,181,625...138,187,434

G

calpain 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CAPN6 mRNA

NCBI chr X:142,585,232...142,610,408
Ensembl chr X:142,585,227...142,610,410

G

calpain 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CAPN8 mRNA

NCBI chr 1:182,392,314...182,462,021
Ensembl chr 1:182,392,572...182,459,917

G

carbonic anhydrase 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CAR10 mRNA

NCBI chr11:92,988,807...93,492,577
Ensembl chr11:92,988,854...93,492,575

G

carbonic anhydrase 11

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CA11 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CAR11 mRNA

PMID:36189433 PMID:36695872

NCBI chr 7:45,348,537...45,354,106
Ensembl chr 7:45,349,267...45,354,106

G

caspase recruitment domain family, member 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CARD11 mRNA

NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337

G

caspase recruitment domain family, member 14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CARD14 mRNA

NCBI chr11:119,197,923...119,236,205
Ensembl chr11:119,198,594...119,236,201

G

CASK interacting protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CASKIN1 mRNA

NCBI chr17:24,706,871...24,727,883
Ensembl chr17:24,707,575...24,727,645

G

caspase 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein]; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein]; Toyocamycin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein]

PMID:33159713 PMID:37286014 PMID:37692514

NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290

G

caspase 3

multiple interactions
increases expression
increases activity
increases cleavage

2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CASP3 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased cleavage of CASP3 protein; PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]; Rosiglitazone promotes the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]
mono-(2-ethylhexyl)phthalate results in increased expression of CASP3 protein
mono-(2-ethylhexyl)phthalate results in increased cleavage of CASP3 protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP3 mRNA
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP3 protein]

PMID:12927354 PMID:19165384 PMID:19720108 PMID:23360888 PMID:24706461 More...

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 7

increases activity
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased activity of CASP7 protein
mono-(2-ethylhexyl)phthalate results in increased expression of CASP7 protein
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP7 protein]

PMID:23360888 PMID:36889213

NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776

G

caspase 8

multiple interactions
increases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CASP8 mRNA; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP8 protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CASP8 mRNA

PMID:31884101 PMID:35861251 PMID:37286014

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

G

caspase 9

increases activity

mono-(2-ethylhexyl)phthalate results in increased activity of CASP9 protein

NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287

G

catalase

multiple interactions
increases expression
increases activity

Cycloheximide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CAT protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA
mono-(2-ethylhexyl)phthalate results in increased activity of CAT protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CAT mRNA

PMID:2306265 PMID:6845354 PMID:31884101 PMID:32522588 PMID:35861251

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

cation channel, sperm associated 4

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CATSPER4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CATSPER4 mRNA

NCBI chr 4:133,939,276...133,954,743
Ensembl chr 4:133,939,281...133,954,694

G

cerebellin 1 precursor protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CBLN1 mRNA

NCBI chr 8:88,195,481...88,199,220
Ensembl chr 8:88,195,033...88,199,237

G

cerebellin 2 precursor protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CBLN2 mRNA

NCBI chr18:86,727,226...86,736,410
Ensembl chr18:86,729,235...86,736,408

G

carbonyl reductase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of CBR1 mRNA

NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393

G

cystathionine beta-synthase

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CBS mRNA

NCBI chr17:31,831,602...31,856,170
Ensembl chr17:31,827,868...31,856,212

G

coiled-coil domain containing 160

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CCDC160 mRNA

NCBI chr X:51,880,045...51,888,351
Ensembl chr X:51,880,077...51,888,345

G

coiled-coil domain containing 163

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of CCDC163 mRNA

NCBI chr 4:116,565,537...116,572,881
Ensembl chr 4:116,565,706...116,608,403

G

coiled-coil domain containing 187

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC187 mRNA

NCBI chr 2:26,161,659...26,184,569
Ensembl chr 2:26,133,481...26,184,569

G

coiled-coil domain containing 27

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CCDC27 mRNA

NCBI chr 4:154,111,101...154,127,202
Ensembl chr 4:154,111,096...154,127,134

G

coiled-coil domain containing 3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CCDC3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CCDC3 mRNA

NCBI chr 2:5,142,587...5,235,682
Ensembl chr 2:5,142,587...5,235,689

G

coiled-coil domain containing 63

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC63 mRNA

NCBI chr 5:122,246,115...122,276,143
Ensembl chr 5:122,246,103...122,278,886

G

coiled-coil domain containing 68

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC68 mRNA

NCBI chr18:70,057,929...70,102,559
Ensembl chr18:70,058,497...70,102,555

G

coiled-coil domain containing 88B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CCDC88B mRNA

NCBI chr19:6,821,991...6,835,586
Ensembl chr19:6,821,991...6,835,579

G

coiled-coil domain containing 92B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC92B mRNA

NCBI chr11:74,510,428...74,532,342
Ensembl chr11:74,510,431...74,532,342

G

coiled-coil domain containing 96

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CCDC96 mRNA

NCBI chr 5:36,641,932...36,645,515
Ensembl chr 5:36,641,932...36,645,516

G

coiled-coil domain containing 9B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCDC9B mRNA

NCBI chr 2:118,584,626...118,593,421
Ensembl chr 2:118,584,639...118,593,142

G

C-C motif chemokine ligand 17

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CCL17 mRNA

NCBI chr 8:95,535,996...95,538,666
Ensembl chr 8:95,537,081...95,538,664

G

C-C motif chemokine ligand 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CCL2 mRNA

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

cellular communication network factor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CCN1 mRNA

NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736

G

cellular communication network factor 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CCN2 mRNA

NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581

G

cellular communication network factor 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CCN5 mRNA

NCBI chr 2:163,662,724...163,675,066
Ensembl chr 2:163,662,781...163,675,066

G

cyclin A1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CCNA1 mRNA

NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922

G

cyclin A2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNA2 mRNA

NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299

G

cyclin B1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB1 mRNA

NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078

G

cyclin B2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNB2 mRNA

NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829

G

cyclin D1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CCND1 mRNA

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

cyclin D2

multiple interactions
decreases expression

Estradiol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CCND2 mRNA]

NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156

G

cyclin D3

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCND3 mRNA

NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616

G

cyclin E1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CCNE1 mRNA

NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959

G

cyclin O

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CCNO mRNA

NCBI chr13:113,124,363...113,127,313
Ensembl chr13:113,124,336...113,127,311

G

C-C motif chemokine receptor 7

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CCR7 mRNA

NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903

G

C-C motif chemokine receptor-like 2

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CCRL2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CCRL2 mRNA

PMID:16809437 PMID:22401849

NCBI chr 9:110,883,902...110,886,586
Ensembl chr 9:110,883,554...110,886,587

G

CD109 antigen

affects expression
decreases expression

mono-(2-ethylhexyl)phthalate affects the expression of CD109 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CD109 mRNA

PMID:21195148 PMID:22401849

NCBI chr 9:78,522,828...78,623,542
Ensembl chr 9:78,522,828...78,623,535

G

CD163 antigen

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CD163 protein
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD163 mRNA]
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of CD163 mRNA

PMID:22143055 PMID:29718165 PMID:30398665

NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486

G

CD1d2 antigen

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CD1D2 mRNA

NCBI chr 3:86,893,875...86,896,843
Ensembl chr 3:86,893,858...86,897,087

G

CD22 antigen

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CD22 mRNA

NCBI chr 7:30,564,829...30,579,767
Ensembl chr 7:30,564,827...30,579,767

G

CD248 antigen, endosialin

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CD248 mRNA

NCBI chr19:5,118,106...5,120,668
Ensembl chr19:5,118,106...5,120,710

G

CD24a antigen

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CD24A mRNA

NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261

G

CD27 antigen

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CD27 mRNA

NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973

G

CD34 antigen

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CD34 mRNA

NCBI chr 1:194,621,239...194,643,587
Ensembl chr 1:194,621,127...194,643,587

G

CD36 molecule

multiple interactions
increases expression
decreases expression

mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD36 mRNA]
mono-(2-ethylhexyl)phthalate results in increased expression of CD36 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CD36 mRNA

PMID:29718165 PMID:35421560 PMID:38113427

NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799

G

CD38 antigen

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CD38 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CD38 mRNA

PMID:36189433 PMID:36695872

NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717

G

CD40 antigen

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CD40 mRNA

NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868

G

CD59b antigen

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CD59 mRNA

NCBI chr 2:103,900,127...103,920,619
Ensembl chr 2:103,896,142...103,921,534

G

CD69 antigen

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CD69 mRNA

NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399

G

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CD74 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CD74 mRNA

PMID:36189433 PMID:38113427

NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724

G

CD86 antigen

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CD86 mRNA

NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443

G

cadherin 17

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CDH17 mRNA

NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895

G

cadherin 2

multiple interactions

[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and affects the localization of CDH2 protein

NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303

G

cadherin related 23 (otocadherin)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CDH23 mRNA

NCBI chr10:60,138,527...60,532,291
Ensembl chr10:60,138,527...60,532,269

G

cadherin 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CDH4 mRNA

NCBI chr 2:179,084,228...179,541,166
Ensembl chr 2:179,084,224...179,541,166

G

cadherin 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CDH8 mRNA

NCBI chr 8:99,751,103...100,144,298
Ensembl chr 8:99,751,103...100,143,103

G

cadherin-related family member 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CDHR2 mRNA

NCBI chr13:54,849,276...54,884,475
Ensembl chr13:54,849,274...54,884,475

G

cyclin dependent kinase 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CDK15 mRNA

NCBI chr 1:59,296,029...59,391,656
Ensembl chr 1:59,296,065...59,392,152

G

cyclin dependent kinase 2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK2 mRNA

NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900

G

cyclin dependent kinase 4

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDK4 mRNA; Estradiol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA]

PMID:19874833 PMID:31884101

NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789

G

cyclin dependent kinase inhibitor 1A

decreases expression
increases activity
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CDKN1A mRNA
mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein
Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein]
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of CDKN1A protein

PMID:21515331 PMID:22401849 PMID:31884101 PMID:36174712 PMID:37364752

NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701

G

cyclin dependent kinase inhibitor 1B

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1B mRNA

NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476

G

cyclin dependent kinase inhibitor 1C

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN1C mRNA

NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787

G

cyclin dependent kinase inhibitor 2A

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2A mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2A mRNA

PMID:31884101 PMID:35861251

NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890

G

cyclin dependent kinase inhibitor 2B

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN2B mRNA

NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276

G

cyclin dependent kinase inhibitor 2C

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CDKN2C mRNA

NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386

G

cyclin dependent kinase inhibitor 2D

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of CDKN2D mRNA

NCBI chr 9:21,199,759...21,202,553
Ensembl chr 9:21,199,706...21,202,703

G

cysteine dioxygenase 1, cytosolic

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CDO1 mRNA

NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462

G

cerebellar degeneration-related protein 2-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CDR2L mRNA

NCBI chr11:115,272,700...115,286,961
Ensembl chr11:115,272,742...115,286,958

G

caudal type homeobox 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CDX1 mRNA

NCBI chr18:61,151,934...61,169,292
Ensembl chr18:61,151,934...61,169,271

G

CCAAT/enhancer binding protein alpha

decreases expression
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein
Colforsin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CEBPA protein]
mono-(2-ethylhexyl)phthalate results in increased expression of CEBPA mRNA

PMID:21832167 PMID:25543134 PMID:27384973

NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353

G

CCAAT/enhancer binding protein beta

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CEBPB mRNA

PMID:25543134 PMID:36695872

NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338

G

CCAAT/enhancer binding protein epsilon

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CEBPE mRNA

NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631

G

chymotrypsin-like elastase family, member 3B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CELA3B mRNA

NCBI chr 4:137,148,319...137,157,831
Ensembl chr 4:137,148,310...137,157,851

G

CUGBP, Elav-like family member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CELF4 mRNA

NCBI chr18:25,610,677...25,887,577
Ensembl chr18:25,610,689...25,887,214

G

cadherin, EGF LAG seven-pass G-type receptor 2

multiple interactions
affects transport
increases phosphorylation

[IC 261 results in decreased activity of CSNK1A1 protein] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CELSR2 protein]
mono-(2-ethylhexyl)phthalate affects the transport of CELSR2 protein

NCBI chr 3:108,298,164...108,323,416
Ensembl chr 3:108,298,167...108,323,383

G

carboxylesterase 1E

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CES1E mRNA

NCBI chr 8:93,927,846...93,956,233
Ensembl chr 8:93,927,846...93,956,247

G

cilia and flagella associated protein 161

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CFAP161 mRNA

NCBI chr 7:83,424,820...83,447,528
Ensembl chr 7:83,423,309...83,444,088

G

cilia and flagella associated protein 52

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CFAP52 mRNA

NCBI chr11:67,815,632...67,856,494
Ensembl chr11:67,815,632...67,856,477

G

cilia and flagella associated protein 99

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CFAP99 mRNA

NCBI chr 5:34,441,107...34,486,205
Ensembl chr 5:34,445,944...34,484,671

G

CASP8 and FADD-like apoptosis regulator

multiple interactions

[FASL affects the susceptibility to mono-(2-ethylhexyl)phthalate] which affects the expression of CFLAR protein

NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043

G

glycoprotein hormones, alpha subunit

multiple interactions
increases expression
increases secretion
affects expression

mono-(2-ethylhexyl)phthalate inhibits the reaction [CGA protein results in increased abundance of Estradiol]
mono-(2-ethylhexyl)phthalate inhibits the reaction [CGA protein results in increased abundance of Progesterone]
mono-(2-ethylhexyl)phthalate results in increased expression of CGA mRNA
mono-(2-ethylhexyl)phthalate results in increased secretion of CGA protein
mono-(2-ethylhexyl)phthalate affects the expression of CGA mRNA

PMID:19501113 PMID:27181934 PMID:28381288 PMID:29089286

NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370

G

cingulin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CGN mRNA

NCBI chr 3:94,667,376...94,695,036
Ensembl chr 3:94,667,376...94,693,826

G

cholesterol 25-hydroxylase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CH25H mRNA

NCBI chr19:34,451,183...34,452,548
Ensembl chr19:34,451,178...34,452,564

G

ChaC, cation transport regulator 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CHAC1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CHAC1 mRNA

PMID:36189433 PMID:36695872

NCBI chr 2:119,181,723...119,184,807
Ensembl chr 2:119,181,710...119,184,862

G

chromatin assembly factor 1, subunit A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CHAF1A mRNA

NCBI chr17:56,347,404...56,375,027
Ensembl chr17:56,347,439...56,379,289

G

choline acetyltransferase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CHAT mRNA

NCBI chr14:32,130,160...32,187,866
Ensembl chr14:32,130,160...32,187,946

G

coiled-coil-helix-coiled-coil-helix domain containing 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CHCHD6 mRNA

NCBI chr 6:89,360,128...89,572,634
Ensembl chr 6:89,360,128...89,572,634

G

chromodomain helicase DNA binding protein 5

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CHD5 mRNA

NCBI chr 4:152,423,103...152,474,651
Ensembl chr 4:152,423,108...152,474,651

G

checkpoint kinase 2

multiple interactions
increases phosphorylation

gingerol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CHEK2 protein]

NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011

G

cell adhesion molecule L1-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHL1 mRNA

NCBI chr 6:103,487,372...103,709,999
Ensembl chr 6:103,487,547...103,727,172

G

chondrolectin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHODL mRNA

NCBI chr16:78,727,729...78,748,624
Ensembl chr16:78,727,836...78,748,621

G

chordin

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CHRD mRNA

NCBI chr16:20,551,528...20,561,132
Ensembl chr16:20,551,877...20,561,134

G

cholinergic receptor, muscarinic 2, cardiac

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHRM2 mRNA

NCBI chr 6:36,364,928...36,505,573
Ensembl chr 6:36,365,019...36,505,349

G

cholinergic receptor, muscarinic 3, cardiac

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHRM3 mRNA

NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883

G

cholinergic receptor, nicotinic, alpha polypeptide 9

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CHRNA9 mRNA

NCBI chr 5:66,092,317...66,134,823
Ensembl chr 5:66,092,264...66,134,669

G

cholinergic receptor, nicotinic, delta polypeptide

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHRND mRNA

NCBI chr 1:87,118,319...87,127,792
Ensembl chr 1:87,118,329...87,127,792

G

carbohydrate sulfotransferase 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHST11 mRNA

NCBI chr10:82,820,274...83,031,738
Ensembl chr10:82,821,332...83,031,734

G

carbohydrate sulfotransferase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CHST2 mRNA

NCBI chr 9:95,282,979...95,289,323
Ensembl chr 9:95,281,345...95,288,775

G

carbohydrate sulfotransferase 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CHST8 mRNA

NCBI chr 7:34,373,893...34,512,136
Ensembl chr 7:34,373,893...34,512,136

G

carbohydrate sulfotransferase 9

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CHST9 mRNA

NCBI chr18:15,584,830...15,893,214
Ensembl chr18:15,584,981...15,893,214

G

cell death-inducing DNA fragmentation factor, alpha subunit-like effector A

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CIDEA mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CIDEA mRNA

PMID:32522588 PMID:36189433

NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855

G

class II transactivator

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CIITA mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CIITA mRNA

NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282

G

ciliary microtubule associated protein 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PIFO mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PIFO mRNA

NCBI chr 3:105,904,273...105,921,962
Ensembl chr 3:105,904,273...105,921,962

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CITED4 mRNA

NCBI chr 4:120,523,760...120,525,017
Ensembl chr 4:120,523,769...120,525,017

G

creatine kinase, muscle

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CKM mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CKM mRNA

NCBI chr 7:19,145,019...19,155,508
Ensembl chr 7:19,138,701...19,156,766

G

creatine kinase, mitochondrial 1, ubiquitous

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CKMT1 mRNA

NCBI chr 2:121,188,257...121,194,218
Ensembl chr 2:121,188,195...121,194,218

G

CLIP associating protein 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CLASP2 mRNA

NCBI chr 9:113,567,776...113,748,765
Ensembl chr 9:113,570,541...113,748,750

G

chloride channel accessory 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CLCA1 mRNA

NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537

G

chloride channel accessory 3A2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CLCA3A2 mRNA

NCBI chr 3:144,486,340...144,525,385
Ensembl chr 3:144,502,320...144,525,255

G

claudin 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CLDN1 mRNA

NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591

G

claudin 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CLDN11 mRNA

NCBI chr 3:31,204,069...31,218,475
Ensembl chr 3:31,204,069...31,218,473

G

claudin 18

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CLDN18 mRNA

NCBI chr 9:99,572,849...99,599,320
Ensembl chr 9:99,571,514...99,599,320

G

claudin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CLDN2 mRNA

NCBI chr X:138,701,552...138,712,135
Ensembl chr X:138,701,577...138,712,135

G

claudin 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CLDN4 mRNA

NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788

G

claudin 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CLDN6 mRNA

NCBI chr17:23,898,345...23,901,417
Ensembl chr17:23,898,223...23,901,420

G

claudin 7

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CLDN7 mRNA

NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711

G

C-type lectin domain family 18, member A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CLEC18A mRNA

NCBI chr 8:111,796,128...111,819,056
Ensembl chr 8:111,785,552...111,819,058

G

C-type lectin domain family 4, member a1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CLEC4A1 mRNA

NCBI chr 6:122,898,807...122,911,578
Ensembl chr 6:122,898,807...122,911,578

G

C-type lectin domain family 7, member a

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CLEC7A mRNA

NCBI chr 6:129,438,554...129,449,748
Ensembl chr 6:129,438,554...129,449,742

G

chloride intracellular channel 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CLIC6 mRNA

NCBI chr16:92,295,035...92,338,129
Ensembl chr16:92,282,624...92,338,131

G

calsyntenin 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CLSTN3 mRNA

NCBI chr 6:124,407,715...124,441,743
Ensembl chr 6:124,407,540...124,441,753

G

clavesin 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CLVS1 mRNA

NCBI chr 4:9,144,753...9,451,691
Ensembl chr 4:9,269,293...9,451,691

G

CKLF-like MARVEL transmembrane domain containing 2B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CMTM2B mRNA

NCBI chr 8:105,048,838...105,057,396
Ensembl chr 8:105,048,862...105,057,396

G

cyclic nucleotide gated channel alpha 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CNGA2 mRNA

NCBI chr X:71,035,455...71,053,824
Ensembl chr X:71,035,455...71,053,824

G

cyclic nucleotide gated channel alpha 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CNGA4 mRNA

NCBI chr 7:105,049,247...105,057,981
Ensembl chr 7:105,053,775...105,057,949

G

connector enhancer of kinase suppressor of Ras 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CNKSR1 mRNA

NCBI chr 4:133,955,352...133,965,737
Ensembl chr 4:133,955,352...133,965,710

G

chondromodulin

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CNMD mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CNMD mRNA

NCBI chr14:79,875,126...79,899,596
Ensembl chr14:79,875,130...79,899,610

G

2',3'-cyclic nucleotide 3' phosphodiesterase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CNP mRNA

NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555

G

canopy FGF signaling regulator 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CNPY1 mRNA

NCBI chr 5:28,405,817...28,450,786
Ensembl chr 5:28,405,817...28,450,804

G

contactin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CNTN2 mRNA

NCBI chr 1:132,437,163...132,470,989
Ensembl chr 1:132,437,165...132,470,994

G

contactin 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CNTN3 mRNA

NCBI chr 6:102,140,265...102,541,575
Ensembl chr 6:102,139,616...102,550,062

G

contactin associated protein-like 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CNTNAP2 mRNA

NCBI chr 6:45,036,995...47,278,330
Ensembl chr 6:45,036,291...47,281,147

G

contactin associated protein-like 5A

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of CNTNAP5A mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CNTNAP5A mRNA

PMID:22401849 PMID:36189433

NCBI chr 1:115,612,467...116,515,053
Ensembl chr 1:115,612,486...116,515,053

G

centriolin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CNTRL mRNA

NCBI chr 2:34,999,504...35,068,834
Ensembl chr 2:34,999,504...35,068,834

G

collagen, type XII, alpha 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of COL12A1 mRNA

NCBI chr 9:79,506,269...79,628,423
Ensembl chr 9:79,506,273...79,626,113

G

collagen, type XIII, alpha 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of COL13A1 mRNA

NCBI chr10:61,674,013...61,814,985
Ensembl chr10:61,674,015...61,814,887

G

collagen, type XXV, alpha 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of COL25A1 mRNA

NCBI chr 3:129,973,992...130,393,533
Ensembl chr 3:129,925,150...130,393,526

G

collagen, type II, alpha 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of COL2A1 mRNA

NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576

G

collagen, type III, alpha 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of COL3A1 mRNA

NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866

G

collagen, type IV, alpha 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of COL4A3 mRNA

NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780

G

collagen, type IV, alpha 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of COL4A4 mRNA

NCBI chr 1:82,426,140...82,564,570
Ensembl chr 1:82,426,144...82,564,570

G

collagen, type IV, alpha 6

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of COL4A6 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of COL4A6 mRNA

PMID:22401849 PMID:36189433

NCBI chr X:139,948,399...140,257,091
Ensembl chr X:139,948,399...140,257,072

G

collagen, type VIII, alpha 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of COL8A1 mRNA

NCBI chr16:57,444,619...57,575,100
Ensembl chr16:57,444,621...57,575,100

G

collectin sub-family member 12

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of COLEC12 mRNA

NCBI chr18:9,707,648...9,877,995
Ensembl chr18:9,707,595...9,882,644

G

cartilage oligomeric matrix protein

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of COMP mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of COMP mRNA

NCBI chr 8:70,826,186...70,834,721
Ensembl chr 8:70,826,208...70,834,716

G

coronin, actin binding protein 2A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CORO2A mRNA

NCBI chr 4:46,536,937...46,601,929
Ensembl chr 4:46,536,937...46,602,202

G

coronin 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CORO6 mRNA

NCBI chr11:77,353,149...77,361,310
Ensembl chr11:77,353,237...77,361,310

G

cytochrome c oxidase subunit 4I1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of COX4I1 protein

NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946

G

cytochrome c oxidase subunit 6A2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of COX6A2 mRNA

NCBI chr 7:127,804,607...127,805,538
Ensembl chr 7:127,804,607...127,805,559

G

cytochrome c oxidase subunit 7A1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of COX7A1 mRNA

NCBI chr 7:29,883,596...29,885,455
Ensembl chr 7:29,883,569...29,885,503

G

ceruloplasmin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CP mRNA

NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309

G

carboxypeptidase A4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CPA4 mRNA

NCBI chr 6:30,568,368...30,592,417
Ensembl chr 6:30,568,368...30,592,417

G

carboxypeptidase A5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CPA5 mRNA

NCBI chr 6:30,611,009...30,631,744
Ensembl chr 6:30,611,009...30,631,744

G

ciliogenesis and planar polarity effector 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RSG1 mRNA

NCBI chr 4:140,941,249...140,947,425
Ensembl chr 4:140,941,267...140,954,067

G

carnitine palmitoyltransferase 1a, liver

decreases expression
affects expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CPT1A mRNA
mono-(2-ethylhexyl)phthalate affects the expression of CPT1A mRNA

PMID:22401849 PMID:32522588

NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733

G

carnitine palmitoyltransferase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CPT2 mRNA

NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807

G

cellular retinoic acid binding protein I

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CRABP1 mRNA

NCBI chr 9:54,672,032...54,680,394
Ensembl chr 9:54,672,032...54,680,394

G

cellular retinoic acid binding protein II

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CRABP2 mRNA

NCBI chr 3:87,856,000...87,860,679
Ensembl chr 3:87,855,973...87,860,683

G

crumbs family member 1, photoreceptor morphogenesis associated

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CRB1 mRNA

NCBI chr 1:139,101,288...139,307,262
Ensembl chr 1:139,124,794...139,304,838

G

corticotropin releasing hormone binding protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CRHBP mRNA

PMID:22401849 PMID:36314267

NCBI chr13:95,567,884...95,581,339
Ensembl chr13:95,567,879...95,581,432

G

corticotropin releasing hormone receptor 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CRHR2 mRNA

NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CRISPLD2 mRNA

NCBI chr 8:120,719,177...120,779,533
Ensembl chr 8:120,719,177...120,779,532

G

crystallin, beta B1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CRYBB1 mRNA

NCBI chr 5:112,403,686...112,417,451
Ensembl chr 5:112,403,681...112,417,451

G

cold shock domain containing C2, RNA binding

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CSDC2 mRNA

NCBI chr15:81,820,960...81,835,142
Ensembl chr15:81,820,960...81,835,142

G

CUB and Sushi multiple domains 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CSMD3 mRNA

NCBI chr15:47,444,034...48,655,954
Ensembl chr15:47,444,033...48,655,459

G

casein kinase 1, alpha 1

multiple interactions

[IC 261 results in decreased activity of CSNK1A1 protein] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of CELSR2 protein]

NCBI chr18:61,687,307...61,723,391
Ensembl chr18:61,688,345...61,723,132

G

chondroitin sulfate proteoglycan 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CSPG4 mRNA

NCBI chr 9:56,772,388...56,807,154
Ensembl chr 9:56,772,317...56,807,154

G

cysteine and glycine-rich protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CSRP1 mRNA

NCBI chr 1:135,614,650...135,679,970
Ensembl chr 1:135,647,799...135,679,970

G

cystatin 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CST11 mRNA

NCBI chr 2:148,610,538...148,613,417
Ensembl chr 2:148,610,529...148,613,417

G

cystatin 12

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CST12 mRNA

NCBI chr 2:148,631,285...148,635,352
Ensembl chr 2:148,631,281...148,635,466

G

cystatin 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CST9 mRNA

NCBI chr 2:148,677,067...148,680,657
Ensembl chr 2:148,677,067...148,680,658

G

cystatin domain containing 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CSTDC1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CSTDC1 mRNA

NCBI chr 2:148,623,929...148,627,856
Ensembl chr 2:148,623,929...148,627,857

G

cystathionine gamma lyase

affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate affects the expression of CTH mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CTH mRNA

PMID:21195148 PMID:36189433

NCBI chr 3:157,599,885...157,630,718
Ensembl chr 3:157,599,885...157,630,714

G

catenin beta 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CTNNB1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and affects the localization of CTNNB1 protein

PMID:22321834 PMID:29940330

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

G

chymotrypsinogen B1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CTRB1 mRNA

NCBI chr 8:112,413,142...112,417,642
Ensembl chr 8:112,413,151...112,417,642

G

cathepsin L

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CTSL mRNA

PMID:16809437 PMID:38113427

NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704

G

cathepsin W

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CTSW mRNA

NCBI chr19:5,515,071...5,518,558
Ensembl chr19:5,515,071...5,518,535

G

cubilin

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CUBN mRNA

NCBI chr 2:13,281,149...13,496,687
Ensembl chr 2:13,281,149...13,496,624

G

C-X-C motif chemokine ligand 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CXCL1 mRNA

PMID:16809437 PMID:36695872

NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974

G

C-X-C motif chemokine ligand 10

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CXCL10 mRNA
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of CXCL10 mRNA

PMID:16809437 PMID:30398665

NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748

G

C-X-C motif chemokine ligand 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CXCL1 mRNA

PMID:27384973 PMID:36695872

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

cytochrome b5 reductase 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYB5R2 mRNA

NCBI chr 7:107,347,653...107,357,407
Ensembl chr 7:107,347,662...107,357,239

G

cytochrome c-1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CYC1 mRNA

NCBI chr15:76,227,711...76,230,460
Ensembl chr15:76,227,723...76,230,460

G

cytochrome c, somatic

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of CYCS mRNA

NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518

G

cytochrome c, testis

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYCT mRNA

NCBI chr 2:76,184,286...76,190,797
Ensembl chr 2:76,184,286...76,190,794

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases activity
decreases expression
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in increased activity of CYP11A1 protein
mono-(2-ethylhexyl)phthalate results in decreased expression of CYP11A1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of CYP11A1 protein
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of CYP11A1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP11A1 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of CYP11A1 mRNA

PMID:22401849 PMID:22525294 PMID:27181934 PMID:29089286 PMID:31884101 More...

NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306

G

cytochrome P450, family 11, subfamily b, polypeptide 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CYP11B1 mRNA

NCBI chr15:74,706,741...74,713,492
Ensembl chr15:74,705,974...74,713,492

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression
affects expression
decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of CYP17A1 mRNA
mono-(2-ethylhexyl)phthalate affects the expression of CYP17A1
mono-(2-ethylhexyl)phthalate results in decreased expression of CYP17A1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of CYP17A1 protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP17A1 mRNA

PMID:16809437 PMID:19560483 PMID:22087261 PMID:31884101

NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases activity
multiple interactions
decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased activity of CYP19A1 protein
mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA
alitretinoin promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA]
mono-(2-ethylhexyl)phthalate results in increased expression of CYP19A1 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP19A1 mRNA

PMID:12706301 PMID:19501113 PMID:19822197 PMID:19874833 PMID:22401849 More...

NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CYP1A1 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CYP1A1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of CYP1A1 mRNA

PMID:15521013 PMID:31884101 PMID:34954075

NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of CYP1B1 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CYP1B1 mRNA]; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of CYP1B1 mRNA

PMID:12706301 PMID:31884101 PMID:34954075

NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYP26A1 mRNA

NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYP26B1 mRNA

NCBI chr 6:84,548,396...84,570,890
Ensembl chr 6:84,548,396...84,570,890

G

cytochrome P450, family 26, subfamily c, polypeptide 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYP26C1 mRNA

NCBI chr19:37,673,560...37,681,774
Ensembl chr19:37,674,029...37,681,846

G

cytochrome P450, family 2, subfamily c, polypeptide 29

increases metabolic processing
multiple interactions

CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate
[CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate; [CYP2C6V1 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid

PMID:22186153 PMID:23545481

NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157

G

cytochrome P450, family 2, subfamily c, polypeptide 38

multiple interactions
increases metabolic processing

[CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C19 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate

NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519

G

cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene

decreases activity

mono-(2-ethylhexyl)phthalate results in decreased activity of CYP2C11 protein

NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733

G

cytochrome P450, family 2, subfamily c, polypeptide 65

increases metabolic processing
multiple interactions

CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate; CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate
[CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of 2-ethyl-5-carboxypentyl phthalate; [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate; [CYP2C9 protein polymorphism results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of phthalic acid; [CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-hydroxyhexyl) phthalate; [CYP2C9 protein results in increased metabolism of mono-(2-ethylhexyl)phthalate] which results in increased chemical synthesis of mono(2-ethyl-5-oxohexyl)phthalate

PMID:22186153 PMID:23545481

NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388

G

cytochrome P450, family 2, subfamily d, polypeptide 12

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CYP2D12 mRNA

NCBI chr15:82,439,244...82,443,614
Ensembl chr15:82,439,273...82,444,604

G

cytochrome P450, family 2, subfamily d, polypeptide 22

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYP2D22 mRNA

NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461

G

cytochrome P450, family 2, subfamily f, polypeptide 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CYP2F2 mRNA

NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085

G

cytochrome P450, family 4, subfamily x, polypeptide 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CYP4X1 mRNA

NCBI chr 4:114,963,518...114,991,276
Ensembl chr 4:114,963,520...114,991,478

G

cytochrome P450, family 51

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of CYP51 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of CYP51 mRNA

PMID:22087261 PMID:37364752

NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746

G

cytochrome P450, family 7, subfamily b, polypeptide 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYP7B1 mRNA

NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502

G

cytohesin 1 interacting protein

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CYTIP mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of CYTIP mRNA

NCBI chr 2:58,019,151...58,085,559
Ensembl chr 2:58,019,149...58,085,544

G

dachshund family transcription factor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DACH1 mRNA

NCBI chr14:98,024,294...98,407,208
Ensembl chr14:98,024,289...98,407,201

G

dishevelled-binding antagonist of beta-catenin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DACT2 mRNA

NCBI chr17:14,415,492...14,424,595
Ensembl chr17:14,415,314...14,424,566

G

deleted in azoospermia-like

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DAZL protein

NCBI chr17:50,586,422...50,600,627
Ensembl chr17:50,586,423...50,600,664

G

dopamine beta hydroxylase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DBH mRNA

NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212

G

DDB1 and CUL4 associated factor 8 like

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DCAF8L mRNA

NCBI chr X:88,447,454...88,453,295
Ensembl chr X:88,447,454...88,453,295

G

dephospho-CoA kinase domain containing

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of DCAKD mRNA

NCBI chr11:102,884,873...102,919,107
Ensembl chr11:102,884,873...102,919,159

G

doublecortin domain containing 2a

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DCDC2A mRNA

NCBI chr13:25,239,126...25,394,689
Ensembl chr13:25,239,987...25,394,689

G

doublecortin-like kinase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DCLK3 mRNA

NCBI chr 9:111,268,149...111,318,679
Ensembl chr 9:111,268,149...111,318,186

G

decorin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DCN mRNA

NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005

G

dopachrome tautomerase

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DCT mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of DCT mRNA

NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656

G

doublecortin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DCX mRNA

NCBI chr X:142,638,838...142,716,392
Ensembl chr X:142,638,838...142,716,307

G

dimethylarginine dimethylaminohydrolase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DDAH1 mRNA

NCBI chr 3:145,464,447...145,600,032
Ensembl chr 3:145,464,430...145,600,032

G

DNA-damage inducible transcript 3

increases expression
affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of DDIT3 mRNA
mono-(2-ethylhexyl)phthalate affects the expression of DDIT3 protein
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of DDIT3 protein]
7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of DDIT3 protein]

PMID:22321834 PMID:37979351 PMID:38048874

NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157

G

DNA-damage-inducible transcript 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DDIT4 mRNA

NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656

G

DNA-damage-inducible transcript 4-like

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DDIT4L mRNA

NCBI chr 3:137,329,433...137,334,093
Ensembl chr 3:137,327,373...137,334,094

G

DEAD box helicase 4

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DDX4 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of DDX4 protein

PMID:30476341 PMID:37364752

NCBI chr13:112,734,867...112,790,342
Ensembl chr13:112,734,867...112,789,009

G

defensin beta 42

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DEFB42 mRNA

NCBI chr14:63,284,445...63,286,052
Ensembl chr14:63,284,440...63,295,598

G

Der1-like domain family, member 3

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of DERL3 mRNA

NCBI chr10:75,729,232...75,731,775
Ensembl chr10:75,729,247...75,731,775

G

diacylglycerol kinase, beta

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DGKB mRNA

NCBI chr12:37,930,169...38,684,238
Ensembl chr12:37,867,725...38,684,238

G

diacylglycerol kinase, iota

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DGKI mRNA

NCBI chr 6:36,814,316...37,281,034
Ensembl chr 6:36,822,957...37,277,119

G

24-dehydrocholesterol reductase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DHCR24 mRNA

NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310

G

7-dehydrocholesterol reductase

affects expression
decreases expression

mono-(2-ethylhexyl)phthalate affects the expression of DHCR7; mono-(2-ethylhexyl)phthalate affects the expression of DHCR7 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of DHCR7 mRNA

PMID:16809437 PMID:19560483 PMID:22401849

NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147

G

dehydrogenase/reductase 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of DHRS3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DHRS3 mRNA

PMID:36189433 PMID:36695872

NCBI chr 4:144,618,712...144,654,214
Ensembl chr 4:144,619,397...144,654,779

G

dehydrogenase/reductase 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DHRS4 protein

NCBI chr14:55,715,880...55,727,797
Ensembl chr14:55,716,215...55,727,797

G

diablo, IAP-binding mitochondrial protein

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DIABLO mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of DIABLO protein

PMID:18755736 PMID:24706461

NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239

G

dicer 1, ribonuclease type III

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DICER1 mRNA

NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211

G

deiodinase, iodothyronine, type II

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DIO2 mRNA

NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812

G

deiodinase, iodothyronine type III

multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of and results in decreased methylation of DIO3 mRNA

NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531

G

divergent protein kinase domain 2A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DIPK2A mRNA

NCBI chr 9:94,399,917...94,420,134
Ensembl chr 9:94,399,917...94,420,134

G

DIRAS family, GTP-binding RAS-like 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of DIRAS2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DIRAS2 mRNA

NCBI chr13:52,658,411...52,685,390
Ensembl chr13:52,658,416...52,685,315

G

dispatched RND transporter family member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DISP3 mRNA

NCBI chr 4:148,320,890...148,372,653
Ensembl chr 4:148,324,721...148,372,422

G

DLG associated protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DLGAP2 mRNA

NCBI chr 8:14,145,793...14,903,426
Ensembl chr 8:14,145,865...14,897,680

G

DLG associated protein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DLGAP3 mRNA

NCBI chr 4:127,062,090...127,130,815
Ensembl chr 4:127,062,997...127,130,815

G

delta like non-canonical Notch ligand 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DLK2 mRNA

NCBI chr17:46,608,342...46,614,197
Ensembl chr17:46,608,347...46,614,197

G

delta like canonical Notch ligand 1

affects expression
increases expression

mono-(2-ethylhexyl)phthalate affects the expression of DLL1 protein
mono-(2-ethylhexyl)phthalate results in increased expression of DLL1 mRNA

NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134

G

delta like canonical Notch ligand 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DLL4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of DLL4 protein

PMID:36988346 PMID:38042133

NCBI chr 2:119,156,286...119,166,145
Ensembl chr 2:119,156,265...119,166,443

G

dystrophin, muscular dystrophy

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DMD mRNA

NCBI chr X:81,858,244...84,248,656
Ensembl chr X:81,992,476...84,249,747

G

dentin matrix protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DMP1 mRNA

NCBI chr 5:104,345,441...104,361,968
Ensembl chr 5:104,350,479...104,361,968

G

dynein, axonemal, heavy chain 14

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DNAH14 mRNA

NCBI chr 1:181,404,158...181,642,306
Ensembl chr 1:181,404,124...181,643,339

G

dynein, axonemal, heavy chain 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DNAH5 mRNA

NCBI chr15:28,155,000...28,472,191
Ensembl chr15:28,203,898...28,472,198

G

dynein, axonemal, heavy chain 8

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DNAH8 mRNA

NCBI chr17:30,845,909...31,094,736
Ensembl chr17:30,843,328...31,096,339

G

dynein, axonemal, heavy chain 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DNAH9 mRNA

NCBI chr11:65,722,150...66,059,379
Ensembl chr11:65,722,108...66,059,377

G

dynein axonemal intermediate chain 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DNAI1 mRNA

NCBI chr 4:41,569,731...41,638,158
Ensembl chr 4:41,569,775...41,638,158

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DNAJB1 mRNA

NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282

G

DnaJ heat shock protein family (Hsp40) member C5 gamma

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DNAJC5G mRNA

NCBI chr 5:31,265,637...31,269,870
Ensembl chr 5:31,263,629...31,269,870

G

delta/notch-like EGF repeat containing

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of DNER mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DNER mRNA

PMID:36189433 PMID:36695872

NCBI chr 1:84,347,560...84,673,942
Ensembl chr 1:84,347,560...84,673,942

G

DNA methyltransferase 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of DNMT1 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA

PMID:22401849 PMID:35861251

NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184

G

DNA methyltransferase 3-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DNMT3L mRNA

NCBI chr10:77,878,121...77,899,456
Ensembl chr10:77,877,781...77,899,456

G

dedicator of cytokinesis 10

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DOCK10 mRNA

NCBI chr 1:80,478,785...80,736,482
Ensembl chr 1:80,478,790...80,736,244

G

dedicator of cytokinesis 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DOCK4 mRNA

NCBI chr12:40,495,956...40,896,873
Ensembl chr12:40,495,951...40,896,873

G

dedicator of cytokinesis 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DOCK5 mRNA

NCBI chr14:67,989,377...68,171,021
Ensembl chr14:67,989,584...68,170,891

G

docking protein 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DOK5 mRNA

NCBI chr 2:170,573,722...170,721,695
Ensembl chr 2:170,573,727...170,721,689

G

dipeptidase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DPEP1 mRNA

NCBI chr 8:123,913,069...123,928,551
Ensembl chr 8:123,912,981...123,928,551

G

dipeptidase 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DPEP2 mRNA

NCBI chr 8:106,711,577...106,732,658
Ensembl chr 8:106,711,576...106,718,391
Ensembl chr 8:106,711,576...106,718,391

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dipeptidylpeptidase 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DPP6 mRNA

NCBI chr 5:27,022,355...27,932,498
Ensembl chr 5:27,022,201...27,932,503

G

developmental pluripotency-associated 3, pseudogene

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DPPA3-PS mRNA

NCBI chr X:36,807,033...36,807,850
Ensembl chr X:36,807,300...36,807,750

G

developmental pluripotency associated 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DPPA4 mRNA

NCBI chr16:48,104,098...48,114,655
Ensembl chr16:48,104,096...48,114,600

G

dermatopontin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DPT mRNA

NCBI chr 1:164,624,232...164,651,843
Ensembl chr 1:164,624,213...164,651,835

G

dpy-19 like C-mannosyltransferase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DPY19L1 mRNA

NCBI chr 9:24,323,074...24,414,436
Ensembl chr 9:24,323,072...24,414,436

G

dihydropyrimidinase-like 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DPYSL4 mRNA

NCBI chr 7:138,665,917...138,681,711
Ensembl chr 7:138,665,917...138,682,620

G

dynein regulatory complex subunit 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DRC1 mRNA

NCBI chr 5:30,486,328...30,524,039
Ensembl chr 5:30,486,386...30,524,039

G

drosha, ribonuclease type III

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DROSHA mRNA

NCBI chr15:12,824,893...12,935,377
Ensembl chr15:12,824,901...12,935,377

G

desmocollin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of DSC2 mRNA

NCBI chr18:20,163,690...20,192,611
Ensembl chr18:20,163,690...20,192,611

G

DS cell adhesion molecule like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DSCAML1 mRNA

NCBI chr 9:45,338,735...45,665,011
Ensembl chr 9:45,337,926...45,665,010

G

dystonin

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of DST mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DST mRNA

PMID:22401849 PMID:36189433

NCBI chr 1:33,946,969...34,347,743
Ensembl chr 1:33,947,306...34,347,742

G

dual specificity phosphatase 1

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DUSP1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of DUSP1 mRNA

PMID:16809437 PMID:22401849

NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102

G

dual specificity phosphatase 26

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DUSP26 mRNA

NCBI chr 8:31,579,555...31,587,074
Ensembl chr 8:31,579,499...31,587,075

G

dual specificity phosphatase 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DUSP4 mRNA

NCBI chr 8:35,274,448...35,289,106
Ensembl chr 8:35,274,451...35,287,048

G

dual specificity phosphatase 5

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of DUSP5 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of DUSP5 mRNA

PMID:16809437 PMID:36189433 PMID:36695872

NCBI chr19:53,517,576...53,530,240
Ensembl chr19:53,517,540...53,530,862

G

dual specificity phosphatase 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of DUSP6 mRNA

PMID:16809437 PMID:36695872

NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351

G

dynein cytoplasmic 1 intermediate chain 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of DYNC1I1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of DYNC1I1 mRNA

NCBI chr 6:5,725,772...6,028,030
Ensembl chr 6:5,725,639...6,028,039

G

early B cell factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EBF1 mRNA

NCBI chr11:44,502,738...44,898,923
Ensembl chr11:44,508,144...44,898,918

G

early B cell factor 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EBF3 mRNA

NCBI chr 7:136,795,400...136,924,528
Ensembl chr 7:136,795,402...136,916,174

G

EBP cholestenol delta-isomerase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of EBP mRNA

PMID:22087261 PMID:37364752

NCBI chr X:8,051,568...8,059,751
Ensembl chr X:8,051,568...8,059,751

G

enoyl coenzyme A hydratase 1, peroxisomal

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ECH1 mRNA

NCBI chr 7:28,524,763...28,531,664
Ensembl chr 7:28,524,642...28,531,672

G

enoyl-Coenzyme A delta isomerase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ECI1 mRNA

NCBI chr17:24,645,657...24,658,290
Ensembl chr17:24,645,615...24,658,322

G

extracellular matrix protein 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ECM1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ECM1 mRNA

PMID:22401849 PMID:36189433

NCBI chr 3:95,641,459...95,646,880
Ensembl chr 3:95,641,459...95,646,881

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endothelin 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of EDN1 mRNA

NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466

G

endothelin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EDN2 mRNA

NCBI chr 4:120,018,403...120,024,557
Ensembl chr 4:120,018,403...120,024,557

G

EF-hand calcium binding domain 10

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of EFCAB10 mRNA

NCBI chr12:33,444,824...33,451,268
Ensembl chr12:33,444,853...33,451,266

G

EF-hand calcium binding domain 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EFCAB8 mRNA

NCBI chr 2:153,615,231...153,686,672
Ensembl chr 2:153,621,851...153,686,671

G

EF hand and coiled-coil domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of EFCC1 mRNA

NCBI chr 6:87,707,577...87,739,410
Ensembl chr 6:87,707,851...87,732,890

G

epidermal growth factor-containing fibulin-like extracellular matrix protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EFEMP1 mRNA

NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743

G

EF hand domain containing 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EFHD1 mRNA

NCBI chr 1:87,192,075...87,238,563
Ensembl chr 1:87,192,085...87,238,561

G

ephrin B2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of EFNB2 mRNA

NCBI chr 8:8,667,235...8,711,242
Ensembl chr 8:8,667,434...8,711,242

G

epidermal growth factor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EGF mRNA

NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965

G

egl-9 family hypoxia-inducible factor 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EGLN1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of EGLN1 protein

NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063

G

egl-9 family hypoxia-inducible factor 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EGLN3 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of EGLN3 protein

NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646

G

early growth response 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of EGR1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EGR1 mRNA

PMID:8764118 PMID:16809437 PMID:36189433

NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037

G

early growth response 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EGR2 mRNA

NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018

G

early growth response 3

increases expression
decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of EGR3 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of EGR3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EGR3 mRNA

PMID:16809437 PMID:36189433

NCBI chr14:70,314,766...70,320,062
Ensembl chr14:70,314,652...70,320,063

G

early growth response 4

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of EGR4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EGR4 mRNA

PMID:16809437 PMID:36189433

NCBI chr 6:85,488,103...85,490,571
Ensembl chr 6:85,488,103...85,490,571

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ets homologous factor

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EHF mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of EHF mRNA

PMID:36189433 PMID:36314267

NCBI chr 2:103,093,776...103,133,620
Ensembl chr 2:103,093,778...103,133,623

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eukaryotic translation initiation factor 2A

multiple interactions
increases phosphorylation

arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2A protein]

NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922

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eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions
increases expression
increases phosphorylation

4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of EIF2AK3 protein modified form]; mono-(2-ethylhexyl)phthalate inhibits the reaction [4-phenylbutyric acid results in decreased expression of EIF2AK3 protein modified form]
mono-(2-ethylhexyl)phthalate results in increased expression of EIF2AK3 protein; mono-(2-ethylhexyl)phthalate results in increased expression of EIF2AK3 protein modified form
mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein]

PMID:36005737 PMID:37692514 PMID:37979351

NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229

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eukaryotic translation initiation factor 5B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of EIF5B mRNA

NCBI chr 1:38,037,091...38,094,660
Ensembl chr 1:38,037,091...38,094,660

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endosome-lysosome associated apoptosis and autophagy regulator 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ELAPOR1 mRNA

NCBI chr 3:108,362,995...108,444,064
Ensembl chr 3:108,363,010...108,443,852

G

ELAV like RNA binding protein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ELAVL3 mRNA

NCBI chr 9:21,926,301...21,963,442
Ensembl chr 9:21,926,301...21,963,319

G

E74 like ETS transcription factor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ELF1 mRNA

NCBI chr14:79,718,619...79,819,916
Ensembl chr14:79,718,634...79,819,934

G

E74-like factor 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ELF3 mRNA

NCBI chr 1:135,181,312...135,186,210
Ensembl chr 1:135,181,313...135,186,306

G

ELOVL fatty acid elongase 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ELOVL2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ELOVL2 mRNA

NCBI chr13:41,335,858...41,373,879
Ensembl chr13:41,335,857...41,373,881

G

ELOVL fatty acid elongase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ELOVL3 mRNA

NCBI chr19:46,120,336...46,124,133
Ensembl chr19:46,120,336...46,124,133

G

elastin microfibril interfacer 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EMILIN3 mRNA

NCBI chr 2:160,748,358...160,754,259
Ensembl chr 2:160,748,357...160,754,248

G

engrailed 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EN1 mRNA

NCBI chr 1:120,530,246...120,535,719
Ensembl chr 1:120,530,147...120,535,721

G

enkurin, TRPC channel interacting protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ENKUR mRNA

NCBI chr 2:21,185,542...21,210,176
Ensembl chr 2:21,185,542...21,210,176

G

ecto-NOX disulfide-thiol exchanger 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ENOX1 mRNA

NCBI chr14:77,393,790...77,959,203
Ensembl chr14:77,394,203...77,959,200

G

glutamyl aminopeptidase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ENPEP mRNA

NCBI chr 3:129,062,826...129,126,398
Ensembl chr 3:129,062,824...129,126,369

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ENPP1 mRNA

NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057

G

ectonucleotide pyrophosphatase/phosphodiesterase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ENPP3 mRNA

NCBI chr10:24,649,712...24,712,093
Ensembl chr10:24,648,304...24,718,721

G

ectonucleoside triphosphate diphosphohydrolase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ENTPD1 mRNA

NCBI chr19:40,600,810...40,730,046
Ensembl chr19:40,600,810...40,730,046

G

ectonucleoside triphosphate diphosphohydrolase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ENTPD3 mRNA

NCBI chr 9:120,368,884...120,397,393
Ensembl chr 9:120,368,884...120,397,393

G

E1A binding protein p300

multiple interactions

mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to EP300 protein]

NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278

G

erythrocyte membrane protein band 4.1 like 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of EPB41L1 mRNA

NCBI chr 2:156,255,918...156,385,134
Ensembl chr 2:156,262,829...156,385,134

G

erythrocyte membrane protein band 4.1 like 3

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of EPB41L3 mRNA

NCBI chr17:69,382,642...69,596,986
Ensembl chr17:69,382,678...69,596,984

G

epithelial cell adhesion molecule

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of EPCAM mRNA

NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557

G

ependymin related 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EPDR1 mRNA

NCBI chr13:19,775,878...19,804,000
Ensembl chr13:19,775,876...19,804,097

G

Eph receptor A5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EPHA5 mRNA

NCBI chr 5:84,199,024...84,565,677
Ensembl chr 5:84,202,620...84,565,241

G

Eph receptor A6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EPHA6 mRNA

NCBI chr16:59,473,424...60,431,196
Ensembl chr16:59,473,846...60,425,894

G

epoxide hydrolase 1, microsomal

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of EPHX1 mRNA

NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469

G

epoxide hydrolase 2, cytoplasmic

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EPHX2 mRNA

NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949

G

erythropoietin

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EPO mRNA

NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504

G

epididymal peptidase inhibitor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EPPIN mRNA

NCBI chr 2:164,430,263...164,435,491
Ensembl chr 2:164,430,263...164,435,514

G

epiplakin 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of EPPK1 mRNA

NCBI chr15:75,973,337...76,004,395
Ensembl chr15:75,973,330...76,004,395

G

erb-b2 receptor tyrosine kinase 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ERBB3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ERBB3 mRNA

PMID:36189433 PMID:36695872

NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521

G

erb-b2 receptor tyrosine kinase 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ERBB4 mRNA

NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218

G

glutamate rich 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ERICH5 mRNA

NCBI chr15:34,453,458...34,474,038
Ensembl chr15:34,453,451...34,474,038

G

glutamate rich 6B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ERICH6B mRNA

NCBI chr14:75,879,662...75,934,165
Ensembl chr14:75,879,689...75,934,157

G

endoplasmic reticulum to nucleus signalling 1

increases expression
multiple interactions
increases phosphorylation

mono-(2-ethylhexyl)phthalate results in increased expression of ERN1 protein; mono-(2-ethylhexyl)phthalate results in increased expression of ERN1 protein modified form
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein]

PMID:36005737 PMID:37692514

NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678

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endoplasmic reticulum to nucleus signalling 2

multiple interactions

mono-(2-ethylhexyl)phthalate promotes the reaction [INS protein results in increased phosphorylation of ERN2 protein]

NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430

G

endoplasmic reticulum oxidoreductase 1 alpha

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ERO1A protein
7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ERO1A protein]

NCBI chr14:45,520,544...45,556,029
Ensembl chr14:45,520,544...45,556,228

G

endothelial cell-specific molecule 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ESM1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ESM1 mRNA

PMID:36189433 PMID:36695872

NCBI chr13:113,346,193...113,354,638
Ensembl chr13:113,346,193...113,354,632

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espin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ESPN mRNA

NCBI chr 4:152,204,788...152,236,871
Ensembl chr 4:152,204,788...152,236,828

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estrogen receptor 1 (alpha)

multiple interactions
affects expression
increases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR1 mRNA; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR1 protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of ESR1 mRNA; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of ESR1 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP2 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP9 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of TIMP2 mRNA]; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR1 protein
mono-(2-ethylhexyl)phthalate results in increased expression of ESR1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of ESR1 protein

PMID:20209442 PMID:31884101 PMID:33049310 PMID:33631300 PMID:35861251 More...

NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614

G

estrogen receptor 2 (beta)

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of ESR2 mRNA
mono-(2-ethylhexyl)phthalate binds to and results in increased activity of ESR2 protein

PMID:31884101 PMID:33049310

NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033

G

extraembryonic, spermatogenesis, homeobox 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ESX1 mRNA

NCBI chr X:136,016,146...136,022,880
Ensembl chr X:136,016,146...136,022,832

G

extended synaptotagmin-like protein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ESYT3 mRNA

NCBI chr 9:99,192,016...99,242,210
Ensembl chr 9:99,192,016...99,240,610

G

ets variant 4

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of ETV4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ETV4 mRNA

PMID:36189433 PMID:36695872

NCBI chr11:101,660,573...101,677,963
Ensembl chr11:101,660,568...101,676,197

G

ets variant 5

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ETV5 mRNA

NCBI chr16:22,200,063...22,258,320
Ensembl chr16:22,200,059...22,258,469

G

coagulation factor X

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of F10 mRNA

NCBI chr 8:13,087,308...13,106,676
Ensembl chr 8:13,087,308...13,106,676

G

F2R like trypsin receptor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of F2RL1 mRNA

NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735

G

coagulation factor III

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of F3 mRNA

NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697

G

fatty acid binding protein 3, muscle and heart

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FABP3 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FABP3 protein

PMID:12706301 PMID:15647598

NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256

G

fatty acid binding protein 4, adipocyte

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate analog results in increased expression of FABP4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FABP4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FABP4 protein
T 0070907 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FABP4 mRNA]

PMID:25543134 PMID:25777084 PMID:27384973 PMID:35421560

NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636

G

fatty acid desaturase domain family, member 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FADS6 mRNA

NCBI chr11:115,169,453...115,188,388
Ensembl chr11:115,170,448...115,188,489

G

Fas apoptotic inhibitory molecule 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FAIM2 mRNA

NCBI chr15:99,394,886...99,432,757
Ensembl chr15:99,394,893...99,426,046

G

family with sequence similarity 107, member A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FAM107A mRNA

NCBI chr14:14,152,166...14,173,503
Ensembl chr14:14,151,750...14,173,499

G

family with sequence similarity 180, member A

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM180A mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of FAM180A

PMID:36189433 PMID:36314267

NCBI chr 6:35,289,678...35,303,076
Ensembl chr 6:35,289,603...35,303,076

G

family with sequence similarity 181, member B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM181B mRNA

NCBI chr 7:92,729,087...92,730,929
Ensembl chr 7:92,729,073...92,731,074

G

family with sequence similarity 43, member B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM43B mRNA

NCBI chr 4:138,121,403...138,123,769
Ensembl chr 4:138,121,403...138,123,839

G

family with sequence similarity 78, member A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FAM78A mRNA

NCBI chr 2:31,932,720...31,977,484
Ensembl chr 2:31,940,098...31,954,923
Ensembl chr 2:31,940,098...31,954,923

G

family with sequence similarity 81, member A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FAM81A mRNA

NCBI chr 9:69,996,586...70,049,840
Ensembl chr 9:69,995,793...70,049,842

G

family with sequence similarity 81, member B

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM81B mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of FAM81B mRNA

NCBI chr13:76,349,827...76,427,034
Ensembl chr13:76,349,827...76,453,191

G

fibroblast activation protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FAP mRNA

NCBI chr 2:62,331,280...62,404,365
Ensembl chr 2:62,331,287...62,404,419

G

fatty acyl CoA reductase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FAR1 mRNA

NCBI chr 7:113,113,008...113,170,713
Ensembl chr 7:113,113,041...113,170,718

G

Fas ligand

affects response to substance
multiple interactions

FASL affects the susceptibility to mono-(2-ethylhexyl)phthalate
[FASL affects the susceptibility to mono-(2-ethylhexyl)phthalate] which affects the expression of CFLAR protein

NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064

G

fatty acid synthase

increases expression
decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of FASN mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of FASN mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of FASN mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of FASN protein

PMID:23118965 PMID:25543134 PMID:27181934 PMID:27384973

NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373

G

FAT atypical cadherin 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FAT1 mRNA

NCBI chr 8:45,386,137...45,505,294
Ensembl chr 8:45,388,484...45,505,294

G

fibulin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FBLN2 mRNA

NCBI chr 6:91,189,442...91,249,522
Ensembl chr 6:91,189,437...91,249,522

G

F-box and leucine-rich repeat protein 22

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FBXL22 mRNA

NCBI chr 9:66,415,738...66,425,752
Ensembl chr 9:66,415,657...66,421,891

G

F-box protein 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FBXO15 mRNA

NCBI chr18:84,952,677...84,999,601
Ensembl chr18:84,952,907...84,999,598

G

F-box protein 32

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FBXO32 mRNA

NCBI chr15:58,039,275...58,078,288
Ensembl chr15:58,039,275...58,078,328

G

F-box protein 41

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FBXO41 mRNA

NCBI chr 6:85,446,556...85,479,976
Ensembl chr 6:85,446,556...85,479,976

G

Fc fragment of IgG binding protein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FCGBP mRNA

NCBI chr 7:27,770,661...27,820,289
Ensembl chr 7:27,770,661...27,820,287

G

farnesyl diphosphate synthetase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FDPS mRNA

PMID:22087261 PMID:22401849

NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266

G

ferredoxin 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of FDX1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FDX1 mRNA

PMID:22087261 PMID:22401849 PMID:36189433

NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856

G

ferredoxin reductase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FDXR mRNA

NCBI chr11:115,158,850...115,167,925
Ensembl chr11:115,158,850...115,167,876

G

Foxf1 adjacent non-coding developmental regulatory RNA

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FENDRR mRNA

NCBI chr 8:121,781,621...121,809,849
Ensembl chr 8:121,781,621...121,809,849

G

fer-1 like family member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FER1L4 mRNA

NCBI chr 2:155,861,059...155,894,939
Ensembl chr 2:155,861,059...155,894,867

G

fer-1 like family member 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FER1L5 mRNA

NCBI chr 1:36,411,264...36,461,191
Ensembl chr 1:36,411,372...36,461,191

G

fibroblast growth factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FGF1 mRNA

NCBI chr18:38,971,725...39,062,532
Ensembl chr18:38,971,726...39,062,525

G

fibroblast growth factor 12

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FGF12 mRNA

NCBI chr16:27,976,535...28,571,995
Ensembl chr16:27,978,850...28,571,820

G

fibroblast growth factor 18

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FGF18 mRNA

NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400

G

fibroblast growth factor 21

increases expression
multiple interactions
increases secretion

mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA
alpha-cyano-4-hydroxycinnamate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]; PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]; PPARA inhibits the reaction [PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]]
mono-(2-ethylhexyl)phthalate results in increased secretion of FGF21 protein

PMID:20123618 PMID:31009676 PMID:32522588 PMID:37692514

NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914

G

fibroblast growth factor 8

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of FGF8 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FGF8 mRNA

PMID:31711903 PMID:36189433

NCBI chr19:45,724,930...45,731,380
Ensembl chr19:45,725,237...45,731,354

G

fibroblast growth factor 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FGF9 mRNA

NCBI chr14:58,308,543...58,350,311
Ensembl chr14:58,308,004...58,350,177

G

fibroblast growth factor receptor 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FGFR3 mRNA

NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412

G

fibroblast growth factor receptor 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FGFR4 mRNA

NCBI chr13:55,300,631...55,316,572
Ensembl chr13:55,300,453...55,316,572

G

formin homology 2 domain containing 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FHOD3 mRNA

NCBI chr18:24,841,445...25,266,564
Ensembl chr18:24,841,680...25,266,558

G

fin bud initiation factor homolog (zebrafish)

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of FIBIN mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FIBIN mRNA

PMID:16809437 PMID:36189433

NCBI chr 2:110,191,270...110,193,338
Ensembl chr 2:110,191,262...110,193,528

G

folliculogenesis specific basic helix-loop-helix

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FIGLA mRNA

NCBI chr 6:85,993,476...85,997,978
Ensembl chr 6:85,993,153...85,997,978

G

filamin A interacting protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FILIP1 mRNA

NCBI chr 9:79,708,461...79,920,135
Ensembl chr 9:79,712,376...79,920,133

G

FK506 binding protein 1a

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FKBP1A mRNA

NCBI chr 2:151,384,403...151,403,611
Ensembl chr 2:151,384,403...151,403,612

G

FK506 binding protein 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FKBP5 mRNA

NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501

G

filaggrin

multiple interactions

[FLG gene polymorphism affects the susceptibility to Diethylhexyl Phthalate] which affects the abundance of mono-(2-ethylhexyl)phthalate

NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993

G

FMS-like tyrosine kinase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FLT1 mRNA

NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821

G

FMS-like tyrosine kinase 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of FLT3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FLT3 mRNA

NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299

G

feline leukemia virus subgroup C cellular receptor 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FLVCR2 mRNA

NCBI chr12:85,793,313...85,860,359
Ensembl chr12:85,793,313...85,860,359

G

formin 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FMN1 mRNA

NCBI chr 2:113,158,029...113,547,113
Ensembl chr 2:113,158,081...113,547,112

G

formin-like 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FMNL3 mRNA

NCBI chr15:99,215,091...99,268,375
Ensembl chr15:99,215,106...99,268,363

G

flavin containing monooxygenase 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of FMO2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FMO2 mRNA

PMID:16809437 PMID:36189433

NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295

G

flavin containing monooxygenase 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FMO3 mRNA

NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097

G

Fmr1 neighbor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FMR1NB mRNA

NCBI chr X:67,805,460...67,848,167
Ensembl chr X:67,805,445...67,848,173

G

fibronectin 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FN1 mRNA

NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359

G

formin binding protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FNBP1 mRNA

NCBI chr 2:30,916,218...31,032,046
Ensembl chr 2:30,916,218...31,032,020

G

fibronectin type III domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FNDC1 mRNA

NCBI chr17:7,957,401...8,046,158
Ensembl chr17:7,957,401...8,046,134

G

folate receptor alpha

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of FOLR1 mRNA

NCBI chr 7:101,507,551...101,519,974
Ensembl chr 7:101,507,538...101,519,995

G

FBJ osteosarcoma oncogene

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of FOS mRNA
mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS protein]

PMID:8764118 PMID:16809437 PMID:22564763

NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047

G

FBJ osteosarcoma oncogene B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FOSB mRNA

NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976

G

forkhead box A1

affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate affects the expression of FOXA1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FOXA1 mRNA

PMID:21195148 PMID:36189433

NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702

G

forkhead box D3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of FOXD3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FOXD3 mRNA

NCBI chr 4:99,544,536...99,546,908
Ensembl chr 4:99,544,536...99,546,859

G

forkhead box D4

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of FOXD4 mRNA

NCBI chr19:24,876,307...24,878,380
Ensembl chr19:24,876,600...24,878,561

G

forkhead box F1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FOXF1 mRNA

NCBI chr 8:121,811,100...121,814,883
Ensembl chr 8:121,811,125...121,814,883

G

forkhead box H1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FOXH1 mRNA

NCBI chr15:76,552,029...76,554,286
Ensembl chr15:76,552,425...76,554,148

G

forkhead box J1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of FOXJ1 mRNA

NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225

G

forkhead box L2

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [Tretinoin results in increased expression of FOXL2 mRNA]
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FOXL2 mRNA; mono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in increased expression of FOXL2 protein]

PMID:30476341 PMID:36189433

NCBI chr 9:98,837,495...98,840,601
Ensembl chr 9:98,837,341...98,840,596

G

forkhead box L2, opposite strand

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FOXL2OS mRNA

NCBI chr 9:98,831,208...98,837,363
Ensembl chr 9:98,831,834...98,837,352

G

forkhead box O1

decreases phosphorylation
decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of FOXO1 protein
mono-(2-ethylhexyl)phthalate results in decreased expression of FOXO1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of FOXO1 mRNA
Genistein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of FOXO1 mRNA]

PMID:31228551 PMID:34942354

NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642

G

forkhead box O6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FOXO6 mRNA

NCBI chr 4:120,124,275...120,144,458
Ensembl chr 4:120,124,276...120,144,546

G

forkhead box R1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of FOXR1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FOXR1 mRNA

NCBI chr 9:44,345,531...44,352,165
Ensembl chr 9:44,345,070...44,352,433

G

forkhead box S1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FOXS1 mRNA

NCBI chr 2:152,773,818...152,775,128
Ensembl chr 2:152,773,818...152,775,128

G

Fras1 related extracellular matrix protein 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FREM2 mRNA

NCBI chr 3:53,421,359...53,566,014
Ensembl chr 3:53,421,359...53,564,776

G

Fras1 related extracellular matrix protein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FREM3 mRNA

NCBI chr 8:81,337,668...81,422,186
Ensembl chr 8:81,337,709...81,421,985

G

FERM domain containing 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of FRMD3 mRNA

NCBI chr 4:73,931,454...74,120,451
Ensembl chr 4:73,931,679...74,120,451

G

FERM domain containing 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FRMD5 mRNA

NCBI chr 2:121,376,010...121,637,580
Ensembl chr 2:121,376,010...121,637,568

G

FERM and PDZ domain containing 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FRMPD4 mRNA

NCBI chr X:166,254,297...167,360,230
Ensembl chr X:166,254,305...167,360,227

G

follicle stimulating hormone beta

multiple interactions
increases expression
decreases expression

mono-(2-ethylhexyl)phthalate inhibits the reaction [FSHB protein results in increased abundance of Estradiol]
mono-(2-ethylhexyl)phthalate results in increased expression of FSHB protein
mono-(2-ethylhexyl)phthalate results in decreased expression of FSHB mRNA

PMID:19501113 PMID:22401849 PMID:34954075

NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001

G

follicle stimulating hormone receptor

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of FSHR mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of FSHR mRNA

PMID:22401849 PMID:31884101

NCBI chr17:89,292,380...89,508,103
Ensembl chr17:89,292,380...89,508,103

G

follistatin-like 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FSTL3 mRNA

NCBI chr10:79,613,108...79,618,464
Ensembl chr10:79,613,106...79,618,464

G

ferritin heavy polypeptide 1

multiple interactions
increases expression

ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FTH1 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FTH1 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of FTH1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of FTH1 protein

NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462

G

ferritin, heavy polypeptide-like 17, member A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FTHL17 mRNA

NCBI chr X:84,293,283...84,313,897
Ensembl chr X:84,293,285...84,313,894

G

ferritin, heavy polypeptide-like 17, member B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FTHL17B mRNA

NCBI chr X:8,828,373...8,829,214
Ensembl chr X:8,828,373...8,829,214

G

ferritin, heavy polypeptide-like 17, member D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FTHL17D mRNA

NCBI chr X:8,852,179...8,852,911
Ensembl chr X:8,852,139...8,852,994

G

ferritin mitochondrial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FTMT mRNA

NCBI chr18:52,464,608...52,466,068
Ensembl chr18:52,464,621...52,466,068

G

FTO alpha-ketoglutarate dependent dioxygenase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FTO mRNA

NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067

G

fucosyltransferase 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FUT9 mRNA

NCBI chr 4:25,609,333...25,800,003
Ensembl chr 4:25,609,332...25,800,244

G

frizzled class receptor 7

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FZD7 mRNA

NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114

G

glucose-6-phosphatase catalytic subunit 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of G6PC1 protein

NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729

G

growth factor receptor bound protein 2-associated protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GAB1 mRNA

NCBI chr 8:81,491,060...81,607,151
Ensembl chr 8:81,491,067...81,607,148

G

gamma-aminobutyric acid type B receptor subunit 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of GABBR2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GABBR2 mRNA

PMID:22401849 PMID:36189433

NCBI chr 4:46,662,318...46,991,714
Ensembl chr 4:46,662,305...46,991,873

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GABRB2 mRNA

NCBI chr11:42,310,342...42,523,418
Ensembl chr11:42,310,584...42,519,855

G

gamma-aminobutyric acid type A receptor, subunit gamma 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GABRG3 mRNA

NCBI chr 7:56,366,211...57,037,173
Ensembl chr 7:56,366,213...57,036,936

G

gamma-aminobutyric acid type A receptor subunit theta

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GABRQ mRNA

NCBI chr X:71,868,769...71,886,213
Ensembl chr X:71,868,784...71,886,208

G

galanin and GMAP prepropeptide

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GAL mRNA

NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544

G

polypeptide N-acetylgalactosaminyltransferase 13

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GALNT13 mRNA

NCBI chr 2:54,326,217...55,008,321
Ensembl chr 2:54,326,329...55,008,321

G

polypeptide N-acetylgalactosaminyltransferase 14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GALNT14 mRNA

NCBI chr17:73,800,202...74,019,138
Ensembl chr17:73,800,223...74,017,448

G

polypeptide N-acetylgalactosaminyltransferase 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GALNT7 mRNA

NCBI chr 8:57,976,859...58,106,089
Ensembl chr 8:57,976,862...58,106,066

G

guanidinoacetate methyltransferase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GAMT mRNA

NCBI chr10:80,093,985...80,096,846
Ensembl chr10:80,093,985...80,096,846

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GAPDH protein

PMID:25543134 PMID:27384973

NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430

G

golgi associated RAB2 interactor 5A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of FAM71E1 mRNA

NCBI chr 7:44,145,923...44,153,690
Ensembl chr 7:44,146,005...44,150,910

G

golgi associated kinase 1A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM198A mRNA

NCBI chr 9:121,780,057...121,817,379
Ensembl chr 9:121,780,054...121,809,275

G

golgi associated kinase 1B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GASK1B mRNA

NCBI chr 3:79,791,795...79,853,585
Ensembl chr 3:79,791,840...79,853,587

G

GATA binding protein 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GATA6 mRNA

NCBI chr18:11,052,510...11,085,636
Ensembl chr18:11,052,064...11,085,635

G

GATA binding protein 6, opposite strand

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GATA6OS mRNA

NCBI chr18:11,042,037...11,052,567
Ensembl chr18:10,987,944...11,052,936

G

guanylate binding protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GBP2 mRNA

NCBI chr 3:142,326,424...142,343,769
Ensembl chr 3:142,326,363...142,343,769

G

gastrulation brain homeobox 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GBX1 mRNA

NCBI chr 5:24,709,424...24,731,846
Ensembl chr 5:24,707,755...24,732,200

G

glucagon receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GCGR mRNA

NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812

G

glucokinase

decreases expression
affects expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GCK protein
mono-(2-ethylhexyl)phthalate affects the expression of GCK protein

PMID:31228551 PMID:38048874

NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081

G

glutamate-cysteine ligase, catalytic subunit

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GCLC mRNA

NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767

G

glutamate-cysteine ligase, modifier subunit

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GCLM mRNA

NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381

G

growth differentiation factor 15

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GDF15 mRNA

NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106

G

glial cell line derived neurotrophic factor

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased expression of FOS protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK1 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK3 protein]

NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056

G

glycerophosphodiester phosphodiesterase domain containing 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GDPD4 mRNA

NCBI chr 7:97,569,151...97,698,870
Ensembl chr 7:97,569,162...97,698,870

G

glial cell line derived neurotrophic factor family receptor alpha 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GFRA2 mRNA

NCBI chr14:71,127,547...71,217,280
Ensembl chr14:71,127,560...71,217,278

G

glial cell line derived neurotrophic factor family receptor alpha 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GFRA4 mRNA

NCBI chr 2:130,881,552...130,885,008
Ensembl chr 2:130,881,552...130,885,008

G

golgi associated, gamma adaptin ear containing, ARF binding protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GGA2 mRNA

NCBI chr 7:121,585,945...121,620,421
Ensembl chr 7:121,585,945...121,620,445

G

gamma-glutamyl hydrolase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GGH mRNA

NCBI chr 4:20,041,963...20,066,111
Ensembl chr 4:20,042,052...20,066,750

G

gap junction protein, alpha 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 protein]

PMID:22321834 PMID:29940330

NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609

G

gap junction protein, alpha 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GJA4 mRNA

NCBI chr 4:127,205,213...127,207,832
Ensembl chr 4:127,205,214...127,207,832

G

gap junction protein, beta 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GJB1 mRNA

NCBI chr X:100,419,982...100,429,235
Ensembl chr X:100,419,984...100,429,235

G

gap junction protein, beta 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of GJB3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GJB3 mRNA

NCBI chr 4:127,219,028...127,224,633
Ensembl chr 4:127,219,028...127,224,637

G

gap junction protein, beta 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GJB4 mRNA

NCBI chr 4:127,234,892...127,247,929
Ensembl chr 4:127,244,879...127,247,874

G

gliomedin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GLDN mRNA

NCBI chr 9:54,193,770...54,249,061
Ensembl chr 9:54,193,770...54,249,070

G

GLI-Kruppel family member GLI3

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of GLI3 mRNA

NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611

G

GLI pathogenesis-related 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GLIPR2 mRNA

NCBI chr 4:43,957,702...43,979,118
Ensembl chr 4:43,957,401...43,979,118

G

glutaredoxin 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GLRX2 mRNA

NCBI chr 1:143,614,787...143,625,416
Ensembl chr 1:143,592,076...143,625,414

G

glycosyltransferase 1 domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GLT1D1 mRNA

NCBI chr 5:127,709,134...127,786,438
Ensembl chr 5:127,709,326...127,786,438

G

glycine-N-acyltransferase-like 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GLYATL3 mRNA

NCBI chr17:41,214,599...41,229,469
Ensembl chr17:41,215,509...41,225,241

G

GM2 ganglioside activator protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GM2A mRNA

NCBI chr11:54,988,811...55,003,855
Ensembl chr11:54,988,941...55,003,855

G

GNAS complex locus

multiple interactions

[PTGS2 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of GNAS protein

NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537

G

guanine nucleotide binding protein (G protein), beta 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GNB3 mRNA

NCBI chr 6:124,811,203...124,817,238
Ensembl chr 6:124,811,203...124,817,238

G

guanine nucleotide binding protein (G protein), gamma 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GNG4 mRNA

NCBI chr13:13,958,644...14,002,480
Ensembl chr13:13,958,644...14,002,481

G

guanine nucleotide binding protein (G protein), gamma 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GNG7 mRNA

NCBI chr10:80,784,463...80,850,742
Ensembl chr10:80,784,458...80,850,779

G

glycine N-methyltransferase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GNMT mRNA

NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094

G

gonadotropin releasing hormone receptor

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GNRHR mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of GNRHR mRNA

PMID:16809437 PMID:34954075

NCBI chr 5:86,328,613...86,345,760
Ensembl chr 5:86,328,613...86,345,760

G

glutamatic-oxaloacetic transaminase 2, mitochondrial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GOT2 mRNA

NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175

G

glycerol-3-phosphate acyltransferase 2, mitochondrial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GPAT2 mRNA

NCBI chr 2:127,266,725...127,278,013
Ensembl chr 2:127,267,119...127,278,012

G

glycerol-3-phosphate dehydrogenase 1 (soluble)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GPD1 protein

NCBI chr15:99,615,468...99,622,895
Ensembl chr15:99,615,396...99,622,886

G

G protein-coupled estrogen receptor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GPER1 mRNA

NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GPLD1 mRNA

NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484

G

G protein-coupled receptor 141

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GPR141 mRNA

NCBI chr13:19,933,850...20,008,499
Ensembl chr13:19,933,852...20,008,427

G

G protein-coupled receptor 157

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GPR157 mRNA

NCBI chr 4:150,171,960...150,190,457
Ensembl chr 4:150,171,822...150,190,384

G

G protein-coupled receptor 20

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GPR20 mRNA

NCBI chr15:73,560,346...73,579,354
Ensembl chr15:73,566,453...73,579,354

G

G protein-coupled receptor 55

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GPR55 mRNA

NCBI chr 1:85,860,927...85,924,781
Ensembl chr 1:85,866,039...85,888,729

G

G-protein coupled receptor 88

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GPR88 mRNA

NCBI chr 3:116,043,304...116,047,123
Ensembl chr 3:116,043,303...116,047,152

G

G protein-coupled receptor, family C, group 5, member A

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of GPRC5A mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GPRC5A mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:135,042,660...135,061,707
Ensembl chr 6:135,042,649...135,061,707

G

glutamic pyruvate transaminase (alanine aminotransferase) 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GPT2 mRNA

NCBI chr 8:86,219,090...86,255,531
Ensembl chr 8:86,219,205...86,254,189

G

glutathione peroxidase 1

decreases activity
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of GPX1 mRNA; Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein]
mono-(2-ethylhexyl)phthalate results in decreased expression of GPX1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of GPX1 protein
zinc protoporphyrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX1 protein]

PMID:20659492 PMID:22087261 PMID:31884101 PMID:36696656

NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542

G

glutathione peroxidase 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GPX3 mRNA

NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203

G

glutathione peroxidase 4

multiple interactions
decreases expression

ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]
mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein
RSL3 compound promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]; zinc protoporphyrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]

PMID:34863575 PMID:36438553 PMID:36696656

NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273

G

gremlin 1, DAN family BMP antagonist

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GREM1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of GREM1 mRNA

NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991

G

gremlin 2, DAN family BMP antagonist

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GREM2 mRNA

NCBI chr 1:174,661,352...174,749,386
Ensembl chr 1:174,661,351...174,749,385

G

glutamate receptor, ionotropic, AMPA3 (alpha 3)

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GRIA3 mRNA

NCBI chr X:40,489,351...40,767,478
Ensembl chr X:40,489,731...40,767,478

G

glutamate receptor, ionotropic, delta 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GRID2 mRNA

NCBI chr 6:63,230,118...64,681,305
Ensembl chr 6:63,232,860...64,681,307

G

glutamate receptor, ionotropic, kainate 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GRIK3 mRNA

NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966

G

glutamate receptor, ionotropic, kainate 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GRIK4 mRNA

NCBI chr 9:42,431,708...42,856,296
Ensembl chr 9:42,429,431...42,855,789

G

glutamate receptor, ionotropic, NMDA2C (epsilon 3)

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GRIN2C mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of GRIN2C mRNA

NCBI chr11:115,139,995...115,158,123
Ensembl chr11:115,139,995...115,158,069

G

glutamate receptor, ionotropic, NMDA3B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GRIN3B mRNA

NCBI chr10:79,806,227...79,813,024
Ensembl chr10:79,806,549...79,813,024

G

glutamate receptor, metabotropic 7

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of GRM7 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GRM7 mRNA

NCBI chr 6:110,622,304...111,544,191
Ensembl chr 6:110,622,542...111,544,191

G

gasdermin E

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GSDME mRNA

NCBI chr 6:50,167,013...50,240,837
Ensembl chr 6:50,165,868...50,240,842

G

glycogen synthase kinase 3 beta

multiple interactions
decreases phosphorylation

mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein]
[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein]

PMID:28526321 PMID:31228551 PMID:37364752

NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446

G

glutathione reductase

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of GSR mRNA

NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191

G

glutathione S-transferase, alpha 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GSTA4 mRNA

NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631

G

glutathione S-transferase, mu 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GSTM1 protein

NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289

G

glutathione S-transferase, mu 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of GSTM2 mRNA

NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769

G

glutathione S-transferase, theta 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of GSTT3 mRNA

NCBI chr10:75,609,951...75,617,256
Ensembl chr10:75,609,949...75,617,248

G

general transcription factor IIA, 1-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GTF2A1L mRNA

NCBI chr17:88,972,921...89,022,585
Ensembl chr17:88,976,088...89,022,580

G

guanylate cyclase 2g

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GUCY2G mRNA

NCBI chr19:55,186,531...55,229,684
Ensembl chr19:55,186,531...55,229,668

G

GULP, engulfment adaptor PTB domain containing 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of GULP1 mRNA

NCBI chr 1:44,590,540...44,835,998
Ensembl chr 1:44,590,671...44,835,998

G

glycogen synthase 1, muscle

increases phosphorylation

mono-(2-ethylhexyl)phthalate results in increased phosphorylation of GYS1 protein

NCBI chr 7:45,084,263...45,106,041
Ensembl chr 7:45,084,268...45,106,043

G

granzyme A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of GZMA mRNA

NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515

G

histocompatibility 2, class II antigen A, beta 1

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of H2-AB1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of H2-AB1 mRNA

NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393

G

histocompatibility 2, class II antigen E beta

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of H2-EB1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of H2-EB1 mRNA

NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648

G

histocompatibility 2, Q region locus 10

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of H2-Q10 mRNA

NCBI chr17:35,780,986...35,785,460
Ensembl chr17:35,780,986...35,785,460

G

histocompatibility 2, Q region locus 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of H2-Q2 mRNA

NCBI chr17:35,561,283...35,565,740
Ensembl chr17:35,561,218...35,565,738

G

histocompatibility 2, Q region locus 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of H2-Q6 mRNA

NCBI chr17:35,643,826...35,649,031
Ensembl chr17:35,643,826...35,649,031

G

histocompatibility 2, Q region locus 7

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of H2-Q7 mRNA

NCBI chr17:35,658,131...35,662,749
Ensembl chr17:35,658,131...35,662,749

G

H2A.X variant histone

increases phosphorylation

mono-(2-ethylhexyl)phthalate results in increased phosphorylation of H2AX protein

NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374

G

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HACE1 mRNA

NCBI chr10:45,453,911...45,588,441
Ensembl chr10:45,453,925...45,588,441

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HADHA mRNA

NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160

G

histidine ammonia lyase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HAL mRNA

NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166

G

hepcidin antimicrobial peptide 2

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HAMP2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of HAMP2 mRNA

NCBI chr 7:30,621,797...30,623,606
Ensembl chr 7:30,621,797...30,624,106

G

hydroxyacid oxidase 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HAO2 mRNA

NCBI chr 3:98,781,835...98,802,692
Ensembl chr 3:98,781,837...98,800,555

G

huntingtin-associated protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HAP1 mRNA

NCBI chr11:100,238,153...100,247,808
Ensembl chr11:100,238,153...100,246,954

G

hyaluronan synthase 2

affects expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate affects the expression of HAS2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HAS2 mRNA
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of HAS2 mRNA]
mono-(2-ethylhexyl)phthalate results in decreased expression of HAS2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of HAS2 protein

PMID:21195148 PMID:36189433 PMID:36889213

NCBI chr15:56,529,023...56,557,942
Ensembl chr15:56,529,023...56,557,935

G

holocytochrome c synthetase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HCCS mRNA

NCBI chr X:168,094,526...168,103,361
Ensembl chr X:168,033,189...168,103,368

G

hypocretin (orexin) receptor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HCRTR1 mRNA

NCBI chr 4:130,024,010...130,033,389
Ensembl chr 4:130,024,010...130,033,152

G

histone deacetylase 6

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of HDAC6 protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK1 protein]; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK3 protein]; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN protein]; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein]; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of AKT1 protein]; tubastatin A inhibits the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of HDAC6 protein]

NCBI chr X:7,796,355...7,814,284
Ensembl chr X:7,796,359...7,814,128

G

histone deacetylase 9

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HDAC9 mRNA

NCBI chr12:34,097,579...34,967,094
Ensembl chr12:34,097,579...34,967,094

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HECW1 mRNA

NCBI chr13:14,401,023...14,697,874
Ensembl chr13:14,401,023...14,697,813

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HECW2 mRNA

NCBI chr 1:53,846,031...54,234,193
Ensembl chr 1:53,846,035...54,234,327

G

hepatocyte cell adhesion molecule

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HEPACAM mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of HEPACAM mRNA

NCBI chr 9:37,278,652...37,297,868
Ensembl chr 9:37,278,647...37,297,871

G

hephaestin-like 1

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HEPHL1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of HEPHL1 mRNA

NCBI chr 9:14,963,137...15,023,466
Ensembl chr 9:14,963,137...15,023,404

G

hes family bHLH transcription factor 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HES5 mRNA

NCBI chr 4:155,042,358...155,046,829
Ensembl chr 4:155,045,380...155,046,828

G

hepatocyte growth factor activator

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HGFAC mRNA

NCBI chr 5:35,198,853...35,205,805
Ensembl chr 5:35,198,853...35,205,805

G

hedgehog acyltransferase-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HHATL mRNA

NCBI chr 9:121,613,082...121,626,604
Ensembl chr 9:121,613,082...121,621,573

G

Hedgehog-interacting protein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HHIP mRNA

NCBI chr 8:80,692,480...80,784,637
Ensembl chr 8:80,692,480...80,784,635

G

hedgehog interacting protein-like 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HHIPL2 mRNA

NCBI chr 1:183,195,395...183,217,962
Ensembl chr 1:183,199,147...183,217,717

G

hypermethylated in cancer 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HIC1 mRNA

NCBI chr11:75,052,203...75,059,970
Ensembl chr11:75,055,391...75,060,345

G

hypoxia inducible factor 1, alpha subunit

increases expression
decreases response to substance
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of HIF1A mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of HIF1A protein
HIF1A gene mutant form results in decreased susceptibility to mono-(2-ethylhexyl)phthalate
HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FTH1 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [HIF1A protein binds to HMOX1 promoter]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased stability of and affects the localization of HIF1A protein

PMID:34627990 PMID:34863575

NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304

G

human immunodeficiency virus type I enhancer binding protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HIVEP1 mRNA

NCBI chr13:42,205,304...42,338,504
Ensembl chr13:42,205,497...42,346,013

G

hexokinase domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HKDC1 mRNA

NCBI chr10:62,218,916...62,259,490
Ensembl chr10:62,218,916...62,258,270

G

homeobox containing 1

multiple interactions

METTL3 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased methylation of HMBOX1 protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased methylation of HMBOX1 protein

NCBI chr14:65,049,049...65,187,354
Ensembl chr14:65,049,049...65,187,320

G

hemicentin 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HMCN1 mRNA

NCBI chr 1:150,438,251...150,869,568
Ensembl chr 1:150,438,275...150,869,186

G

hemicentin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HMCN2 mRNA

NCBI chr 2:31,204,273...31,350,751
Ensembl chr 2:31,204,427...31,350,750

G

high mobility group AT-hook 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of HMGA2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HMGA2 mRNA

PMID:36189433 PMID:36695872

NCBI chr10:120,197,173...120,312,374
Ensembl chr10:120,197,180...120,312,374

G

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of HMGCR mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of HMGCR mRNA

PMID:23118965 PMID:27181934

NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444

G

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HMGCS1 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of HMGCS1 mRNA

PMID:22087261 PMID:22401849

NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796

G

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HMGCS2 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of HMGCS2 mRNA

NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054

G

heme oxygenase 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein
Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]; ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [HIF1A protein binds to HMOX1 promoter]
zinc protoporphyrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]

PMID:34863575 PMID:36696656 PMID:37286014 PMID:37692514

NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217

G

homer scaffolding protein 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HOMER3 mRNA

NCBI chr 8:70,735,529...70,747,011
Ensembl chr 8:70,735,477...70,747,011

G

HORMA domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HORMAD1 mRNA

NCBI chr 3:95,466,988...95,495,174
Ensembl chr 3:95,466,988...95,494,982

G

Hoxa transcript antisense RNA, myeloid-specific 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOTAIRM1 mRNA

NCBI chr 6:52,135,504...52,139,000
Ensembl chr 6:52,133,882...52,139,099

G

homeobox A1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA1 mRNA

NCBI chr 6:52,132,573...52,135,299
Ensembl chr 6:52,132,570...52,135,297

G

homeobox A13

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HOXA13 mRNA

NCBI chr 6:52,235,833...52,237,865
Ensembl chr 6:52,234,674...52,237,788

G

homeobox A2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of HOXA2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA2 mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:52,139,389...52,141,808
Ensembl chr 6:52,139,397...52,141,811

G

homeobox A3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA3 mRNA

NCBI chr 6:52,146,039...52,190,316
Ensembl chr 6:52,146,042...52,190,316

G

homeobox A4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA4 mRNA

NCBI chr 6:52,166,662...52,168,683
Ensembl chr 6:52,166,651...52,168,733

G

homeobox A5

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of HOXA5 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA5 mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:52,178,768...52,181,437
Ensembl chr 6:52,178,734...52,181,567

G

homeobox A6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXA6 mRNA

NCBI chr 6:52,181,838...52,185,652
Ensembl chr 6:52,183,268...52,185,702

G

Hoxa cluster antisense RNA 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of HOXA-AS3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXAAS3 mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:52,178,104...52,190,577
Ensembl chr 6:52,152,197...52,192,056

G

homeobox B1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXB1 mRNA

NCBI chr11:96,256,547...96,259,082
Ensembl chr11:96,256,578...96,259,082

G

homeobox B3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXB3 mRNA

NCBI chr11:96,197,927...96,238,756
Ensembl chr11:96,214,152...96,238,756

G

homeobox B4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXB4 mRNA

NCBI chr11:96,209,093...96,212,464
Ensembl chr11:96,209,093...96,212,464

G

homeobox B5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HOXB5 mRNA

NCBI chr11:96,194,338...96,196,947
Ensembl chr11:96,194,162...96,196,947

G

homeobox B7

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HOXB7 mRNA

NCBI chr11:96,176,431...96,180,989
Ensembl chr11:96,177,449...96,180,988

G

homeobox B9

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HOXB9 mRNA

NCBI chr11:96,162,156...96,167,421
Ensembl chr11:96,162,283...96,167,421

G

homeobox C5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HOXC5 mRNA

NCBI chr15:102,922,440...102,925,861
Ensembl chr15:102,875,878...102,925,861

G

hippocalcin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HPCA mRNA

NCBI chr 4:129,005,363...129,019,712
Ensembl chr 4:129,005,363...129,015,829

G

hemopexin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HPX mRNA

NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344

G

histidine rich carboxyl terminus 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HRCT1 mRNA

NCBI chr 4:43,727,198...43,728,110
Ensembl chr 4:43,727,188...43,728,639

G

histamine receptor H1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HRH1 mRNA

NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257

G

harakiri, BCL2 interacting protein (contains only BH3 domain)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HRK mRNA

NCBI chr 5:118,307,829...118,327,543
Ensembl chr 5:118,302,713...118,327,543

G

heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HS3ST3A1 mRNA

NCBI chr11:64,326,158...64,413,667
Ensembl chr11:64,326,158...64,413,667

G

hydroxysteroid 11-beta dehydrogenase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HSD11B1 mRNA

NCBI chr 1:192,903,917...192,946,345
Ensembl chr 1:192,903,942...192,946,383

G

hydroxysteroid 11-beta dehydrogenase 2

decreases activity
affects expression
decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased activity of HSD11B2 protein
mono-(2-ethylhexyl)phthalate affects the expression of HSD11B2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of HSD11B2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HSD11B2 mRNA

PMID:19786001 PMID:21195148 PMID:36189433 PMID:37886449

NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620

G

hydroxysteroid (17-beta) dehydrogenase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HSD17B1 mRNA; [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD17B1 mRNA

PMID:31884101 PMID:36189433

NCBI chr11:100,968,792...100,972,014
Ensembl chr11:100,969,237...100,971,353

G

hydroxysteroid (17-beta) dehydrogenase 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HSD17B2 mRNA

NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HSD17B3 mRNA

NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044

G

hydroxysteroid (17-beta) dehydrogenase 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HSD17B4 mRNA

NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of HSD3B1 mRNA

NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110

G

hydroxysteroid dehydrogenase like 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HSDL2 mRNA

NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689

G

heat shock protein 90, alpha (cytosolic), class A member 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HSP90AA1 mRNA

NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162

G

heat shock protein 1B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HSPA1B mRNA

NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214

G

heat shock protein 5

multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate inhibits the reaction [4-phenylbutyric acid results in decreased expression of HSPA5 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of HSPA5 protein
mono-(2-ethylhexyl)phthalate results in increased expression of GRP78 protein
7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HSPA5 protein]; arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of GRP78 protein]

PMID:36005737 PMID:37979351

NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559

G

5-hydroxytryptamine (serotonin) receptor 1B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HTR1B mRNA

NCBI chr 9:81,510,344...81,515,885
Ensembl chr 9:81,510,344...81,515,881

G

5-hydroxytryptamine (serotonin) receptor 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HTR6 mRNA

NCBI chr 4:138,787,017...138,802,881
Ensembl chr 4:138,788,419...138,802,881

G

5-hydroxytryptamine (serotonin) receptor 7

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of HTR7 mRNA

NCBI chr19:35,935,815...36,035,533
Ensembl chr19:35,936,134...36,034,907

G

HtrA serine peptidase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of HTRA1 mRNA

NCBI chr 7:130,537,933...130,587,388
Ensembl chr 7:130,537,841...130,587,390

G

hyccin PI4KA lipid kinase complex subunit 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of HYCC1 mRNA

NCBI chr 5:24,120,274...24,235,694
Ensembl chr 5:24,120,274...24,235,688

G

intercellular adhesion molecule 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ICAM1 protein

NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113

G

inhibitor of DNA binding 1, HLH protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ID1 mRNA

NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330

G

isocitrate dehydrogenase 1 (NADP+), soluble

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IDH1 mRNA

NCBI chr 1:65,197,775...65,225,638
Ensembl chr 1:65,197,775...65,225,659

G

immediate early response 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of IER3 mRNA

NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815

G

interferon activated gene 203

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IFI203 mRNA

NCBI chr 1:173,747,966...173,770,432
Ensembl chr 1:173,747,973...173,770,238

G

interferon induced transmembrane protein 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IFITM10 mRNA

NCBI chr 7:141,879,572...141,927,526
Ensembl chr 7:141,879,574...141,927,490

G

interferon gamma

multiple interactions
increases secretion

mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD163 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD36 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MARCO mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MMP9 mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]; mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]
mono-(2-ethylhexyl)phthalate results in increased secretion of IFNG protein

PMID:29718165 PMID:37886449

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

G

interferon lambda 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of IFNL3 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of IFNL3 protein

NCBI chr 7:28,208,209...28,209,957
Ensembl chr 7:28,208,261...28,209,880

G

insulin-like growth factor 2 mRNA binding protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IGF2BP1 mRNA

NCBI chr11:95,847,989...95,896,770
Ensembl chr11:95,847,989...95,896,766

G

insulin-like growth factor 2, opposite strand

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of IGF2-AS mRNA

NCBI chr 7:142,213,417...142,224,093
Ensembl chr 7:142,213,430...142,224,093

G

insulin-like growth factor binding protein 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of IGFBP3 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of and results in increased methylation of IGFBP3 mRNA

PMID:36314267 PMID:36695872

NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923

G

insulin-like growth factor binding protein 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IGFBP6 mRNA

NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946

G

immunoglobulin heavy constant alpha

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of IGHA mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IGHA mRNA

NCBI chr12:113,219,824...113,223,856
Ensembl chr12:113,218,450...113,223,856

G

immunoglobulin heavy constant delta

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IGHD mRNA

NCBI chr12:113,371,155...113,379,944
Ensembl chr12:113,370,224...113,379,944

G

Immunoglobulin heavy constant epsilon

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IGHE mRNA

NCBI chr12:113,232,883...113,236,868
Ensembl chr12:113,232,880...113,236,868

G

immunoglobulin heavy constant mu

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IGHM mRNA

NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350

G

IgLON family member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IGLON5 mRNA

NCBI chr 7:43,122,325...43,139,635
Ensembl chr 7:43,122,328...43,139,499

G

immunoglobulin superfamily, member 10

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of IGSF10 mRNA

NCBI chr 3:59,224,156...59,256,836
Ensembl chr 3:59,224,156...59,251,815

G

inhibitor of kappaB kinase gamma

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IKBKG mRNA

NCBI chr X:73,436,883...73,498,013
Ensembl chr X:73,436,896...73,497,460

G

IKAROS family zinc finger 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IKZF1 mRNA

NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926

G

interleukin 10

multiple interactions
increases expression
decreases expression

epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL10 protein]
mono-(2-ethylhexyl)phthalate results in decreased expression of IL10 protein

PMID:37286014 PMID:37692514

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

G

interleukin 16

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IL16 mRNA

NCBI chr 7:83,292,027...83,395,479
Ensembl chr 7:83,292,033...83,394,934

G

interleukin 17 receptor D

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IL17RD mRNA

NCBI chr14:26,760,990...26,829,243
Ensembl chr14:26,760,898...26,829,243

G

interleukin 1 alpha

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of IL1A mRNA

NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892

G

interleukin 1 beta

multiple interactions
increases expression
increases secretion

4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein]; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B mRNA]; Toyocamycin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein]
mono-(2-ethylhexyl)phthalate results in increased expression of IL1B mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein
mono-(2-ethylhexyl)phthalate results in increased secretion of IL1B protein

PMID:29718165 PMID:31016965 PMID:37286014 PMID:37692514

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

G

interleukin 1 receptor accessory protein-like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IL1RAPL1 mRNA

NCBI chr X:85,784,543...87,159,554
Ensembl chr X:85,784,476...87,159,251

G

interleukin 2

increases secretion

mono-(2-ethylhexyl)phthalate results in increased secretion of IL2 protein

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

G

interleukin 22 receptor, alpha 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IL22RA1 mRNA

NCBI chr 4:135,455,470...135,482,694
Ensembl chr 4:135,455,483...135,479,451

G

interleukin 27 receptor, alpha

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of IL27RA mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IL27RA mRNA

PMID:22401849 PMID:36189433

NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218

G

interleukin 33

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IL33 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL33 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA]; 5'-methylthioadenosine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA]; [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased secretion of IL33 protein; anacardic acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA]; Apigenin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA]; kaempferol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA]; mono-(2-ethylhexyl)phthalate promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL33 mRNA]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased secretion of IL33 protein

PMID:36189433 PMID:37545493

NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118

G

interleukin 34

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IL34 mRNA

NCBI chr 8:111,467,809...111,532,579
Ensembl chr 8:111,468,461...111,532,556

G

interleukin 4 induced 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of IL4I1 mRNA

NCBI chr 7:44,485,712...44,490,233
Ensembl chr 7:44,465,811...44,490,233

G

interleukin 6

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of IL6 mRNA
mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 mRNA]
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased expression of IL6 mRNA

PMID:27384973 PMID:29718165 PMID:30398665

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

interleukin 9 receptor

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of IL9R mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IL9R mRNA

NCBI chr11:32,137,544...32,155,283
Ensembl chr11:32,137,541...32,150,279

G

inhibin alpha

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of INHA mRNA

NCBI chr 1:75,483,872...75,487,010
Ensembl chr 1:75,483,721...75,487,010

G

inhibin beta-E

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of INHBE mRNA

NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280

G

inositol polyphosphate-4-phosphatase, type II

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of INPP4B mRNA

NCBI chr 8:82,068,895...82,865,553
Ensembl chr 8:82,069,185...82,854,543

G

insulin I

multiple interactions
increases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein; Akt-I-1,2 compound inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]; Cytochalasin B inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]; mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]; Wortmannin inhibits the reaction [mono-(2-ethylhexyl)phthalate promotes the reaction [INS1 protein results in increased uptake of Glucose]]
mono-(2-ethylhexyl)phthalate results in increased expression of INS1 mRNA
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of and results in decreased phosphorylation of INSR protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB13 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB8A protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SLC2A4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SRC protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STX4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STXBP3 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STXBP4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of TBC1D4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of SLC2A4 protein; mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of LNPEP protein]; mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of SNAP23 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased abundance of Glycogen]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of ARRB2 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]

PMID:25543134 PMID:27384973 PMID:28526321 PMID:31009676

NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914

G

insulin II

decreases activity
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein
mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased expression of and results in increased phosphorylation of AKT1 protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [INS protein results in increased phosphorylation of ERN2 protein]
[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein; [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein]

PMID:31009676 PMID:31228551

NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118

G

INSC spindle orientation adaptor protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of INSC mRNA

NCBI chr 7:114,342,931...114,449,615
Ensembl chr 7:114,342,929...114,449,618

G

insulin-like 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of INSL3 mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of INSL3 mRNA

PMID:22087261 PMID:27181934

NCBI chr 8:72,141,896...72,143,221
Ensembl chr 8:72,141,858...72,143,219

G

insulin receptor

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of and results in decreased phosphorylation of INSR protein

NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617

G

inhibitory synaptic factor family member 2B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of INSYN2B mRNA

NCBI chr11:34,264,822...34,372,642
Ensembl chr11:34,264,758...34,372,640

G

IQ motif containing H

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IQCH mRNA

NCBI chr 9:63,328,522...63,509,808
Ensembl chr 9:63,328,737...63,509,775

G

IQ motif containing GTPase activating protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of IQGAP2 mRNA

NCBI chr13:95,763,685...96,028,788
Ensembl chr13:95,763,682...96,028,991

G

IQ motif and Sec7 domain 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IQSEC3 mRNA

NCBI chr 6:121,349,886...121,450,697
Ensembl chr 6:121,349,892...121,450,637

G

IQ motif and ubiquitin domain containing

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IQUB mRNA

NCBI chr 6:24,444,864...24,515,066
Ensembl chr 6:24,444,864...24,515,066

G

interferon regulatory factor 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of IRF1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of IRF1 protein
IRF1 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 mRNA]; IRF1 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 protein]

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

G

insulin receptor substrate 1

decreases expression
multiple interactions
decreases phosphorylation

mono-(2-ethylhexyl)phthalate results in decreased expression of IRS1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of IRS1 protein
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein
mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of IRS1 protein
[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of IRS1 protein]
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of IRS1 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased phosphorylation of IRS1 protein]

PMID:25543134 PMID:28526321 PMID:31009676 PMID:31228551

NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137

G

insulin receptor substrate 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of IRS2 mRNA

NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458

G

insulin receptor substrate 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of IRS4 mRNA

NCBI chr X:140,493,994...140,508,213
Ensembl chr X:140,493,994...140,508,259

G

Iroquois related homeobox 3

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of IRX3 mRNA

NCBI chr 8:92,525,139...92,528,282
Ensembl chr 8:92,525,153...92,528,695

G

Iroquois homeobox 5

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of IRX5 mRNA

NCBI chr 8:93,084,424...93,088,084
Ensembl chr 8:93,084,253...93,102,914

G

ISG15 ubiquitin-like modifier

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ISG15 mRNA

NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253

G

integrin alpha 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ITGA2 mRNA

NCBI chr13:114,969,617...115,068,588
Ensembl chr13:114,969,617...115,068,636

G

integrin alpha 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ITGA3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ITGA3 mRNA

PMID:22401849 PMID:36189433

NCBI chr11:94,935,301...94,967,637
Ensembl chr11:94,935,300...94,967,627

G

integrin alpha 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ITGA4 mRNA

NCBI chr 2:79,084,767...79,163,458
Ensembl chr 2:79,085,770...79,163,467

G

integrin alpha 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ITGA6 mRNA

NCBI chr 2:71,617,236...71,688,761
Ensembl chr 2:71,575,960...71,688,760

G

integrin beta 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ITGB3 mRNA

NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302

G

integrin beta 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ITGB4 mRNA

NCBI chr11:115,865,556...115,899,238
Ensembl chr11:115,865,535...115,899,238

G

inter-alpha trypsin inhibitor, heavy chain 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ITIH1 mRNA

NCBI chr14:30,651,137...30,665,246
Ensembl chr14:30,651,137...30,665,246

G

inter-alpha trypsin inhibitor, heavy chain 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ITIH3 mRNA

NCBI chr14:30,630,529...30,645,748
Ensembl chr14:30,630,529...30,645,717

G

inter-alpha-trypsin inhibitor heavy chain family member 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ITIH6 mRNA

NCBI chr X:149,609,892...149,640,732
Ensembl chr X:149,609,968...149,639,936

G

inositol 1,4,5-trisphosphate 3-kinase B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ITPKB mRNA

NCBI chr 1:180,156,655...180,252,367
Ensembl chr 1:180,158,050...180,252,367

G

jagged 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of JAG1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of JAG1 protein

PMID:36988346 PMID:38042133

NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564

G

jagged 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of JAG2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of JAG2 protein

NCBI chr12:112,871,439...112,893,437
Ensembl chr12:112,871,439...112,893,396

G

Janus kinase 3

multiple interactions

[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in decreased methylation of JAK3 promoter; [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased expression of JAK3 mRNA

NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219

G

janus kinase and microtubule interacting protein 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of JAKMIP3 mRNA

NCBI chr 7:138,542,057...138,663,893
Ensembl chr 7:138,542,459...138,663,892

G

junction adhesion molecule 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of JAM2 mRNA

NCBI chr16:84,571,011...84,623,268
Ensembl chr16:84,571,011...84,622,816

G

jumonji and AT-rich interaction domain containing 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of JARID2 mRNA

NCBI chr13:44,881,817...45,075,119
Ensembl chr13:44,882,950...45,075,119

G

jun proto-oncogene

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of JUN mRNA

PMID:8764118 PMID:9013627 PMID:16809437

NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459

G

jun B proto-oncogene

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNA
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNA]

PMID:8764118 PMID:16809437

NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347

G

kalirin, RhoGEF kinase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KALRN mRNA

NCBI chr16:33,789,443...34,393,647
Ensembl chr16:33,789,443...34,393,902

G

katanin p60 subunit A-like 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KATNAL2 mRNA

NCBI chr18:77,063,725...77,135,007
Ensembl chr18:77,064,844...77,135,004

G

Kazal-type serine peptidase inhibitor domain 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KAZALD1 mRNA

NCBI chr19:45,063,404...45,067,728
Ensembl chr19:45,063,680...45,067,728

G

potassium voltage-gated channel, shaker-related subfamily, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNA1 mRNA

NCBI chr 6:126,613,426...126,622,764
Ensembl chr 6:126,617,360...126,623,347

G

potassium voltage-gated channel, shaker-related subfamily, member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of KCNA2 mRNA

NCBI chr 3:106,998,203...107,022,321
Ensembl chr 3:107,008,462...107,022,321

G

potassium voltage-gated channel, shaker-related subfamily, beta member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KCNAB3 mRNA

PMID:22401849 PMID:36314267

NCBI chr11:69,217,084...69,223,867
Ensembl chr11:69,217,084...69,223,868

G

potassium voltage gated channel, Shab-related subfamily, member 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KCNB1 mRNA

NCBI chr 2:166,937,889...167,032,088
Ensembl chr 2:166,937,889...167,032,075

G

potassium voltage gated channel, Shaw-related subfamily, member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNC2 mRNA

NCBI chr10:112,105,803...112,302,209
Ensembl chr10:112,107,026...112,302,929

G

potassium voltage-gated channel, Shal-related family, member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KCND3 mRNA

NCBI chr 3:105,359,206...105,581,318
Ensembl chr 3:105,359,646...105,581,318

G

potassium voltage-gated channel, Isk-related subfamily, member 1

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNE1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of KCNE1 mRNA

NCBI chr16:92,142,889...92,156,356
Ensembl chr16:92,142,870...92,156,356

G

potassium voltage-gated channel, subfamily G, member 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of KCNG2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNG2 mRNA

NCBI chr18:80,337,731...80,407,469
Ensembl chr18:80,337,761...80,407,469

G

potassium voltage-gated channel, subfamily H (eag-related), member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNH1 mRNA

NCBI chr 1:191,871,759...192,192,467
Ensembl chr 1:191,873,082...192,192,467

G

potassium voltage-gated channel, subfamily H (eag-related), member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNH5 mRNA

NCBI chr12:74,943,991...75,224,625
Ensembl chr12:74,943,994...75,224,106

G

Kv channel-interacting protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNIP2 mRNA

NCBI chr19:45,780,785...45,804,948
Ensembl chr19:45,780,278...45,804,500

G

potassium inwardly-rectifying channel, subfamily J, member 16

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KCNJ16 mRNA

NCBI chr11:110,858,859...110,918,794
Ensembl chr11:110,858,859...110,918,794

G

potassium inwardly-rectifying channel, subfamily J, member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of KCNJ5 mRNA

NCBI chr 9:32,226,002...32,255,640
Ensembl chr 9:32,226,003...32,255,646

G

potassium inwardly-rectifying channel, subfamily K, member 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KCNK6 mRNA

NCBI chr 7:28,921,353...28,931,947
Ensembl chr 7:28,921,351...28,931,940

G

potassium large conductance calcium-activated channel, subfamily M, beta member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNMB1 mRNA

NCBI chr11:33,912,955...33,923,641
Ensembl chr11:33,913,013...33,923,641

G

potassium large conductance calcium-activated channel, subfamily M, beta member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNMB4 mRNA

NCBI chr10:116,251,951...116,309,787
Ensembl chr10:116,253,766...116,309,783

G

potassium large conductance calcium-activated channel, subfamily M, beta member 4, opposite strand 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNMB4OS2 mRNA

NCBI chr10:116,309,068...116,310,892
Ensembl chr10:116,309,068...116,311,224

G

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNN2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of KCNN2 mRNA

PMID:36189433 PMID:36314267

NCBI chr18:45,401,754...45,818,954
Ensembl chr18:45,401,927...45,818,950

G

K+ voltage-gated channel, subfamily S, 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNS2 mRNA

NCBI chr15:34,837,501...34,843,553
Ensembl chr15:34,837,501...34,843,553

G

potassium channel, subfamily T, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNT1 mRNA

NCBI chr 2:25,753,807...25,808,285
Ensembl chr 2:25,753,746...25,808,285

G

potassium channel, subfamily U, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KCNU1 mRNA

NCBI chr 8:26,338,656...26,427,971
Ensembl chr 8:26,339,651...26,427,967

G

lysine demethylase 5D

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KDM5D mRNA

NCBI chr Y:897,566...946,316
Ensembl chr Y:897,788...956,786

G

lysine (K)-specific demethylase 7A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KDM7A mRNA

NCBI chr 6:39,113,554...39,183,707
Ensembl chr 6:39,113,557...39,183,723

G

KH domain containing 1A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KHDC1A mRNA

NCBI chr 1:21,419,901...21,422,423
Ensembl chr 1:21,419,865...21,422,424

G

KH domain containing 1C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KHDC1C mRNA

NCBI chr 1:21,438,555...21,439,967
Ensembl chr 1:21,438,555...21,441,069

G

KH domain containing 3, subcortical maternal complex member

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KHDC3 mRNA

NCBI chr 9:73,008,660...73,013,915
Ensembl chr 9:73,009,118...73,011,720

G

kinesin family member 21B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KIF21B mRNA

NCBI chr 1:136,059,128...136,105,739
Ensembl chr 1:136,059,127...136,105,736

G

kinesin family member 27

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of KIF27 mRNA

NCBI chr13:58,432,541...58,512,559
Ensembl chr13:58,435,316...58,506,936

G

kinesin family member 5C

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KIF5C mRNA

NCBI chr 2:49,509,298...49,664,790
Ensembl chr 2:49,509,310...49,664,790

G

kinesin family member 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KIF6 mRNA

NCBI chr17:49,922,121...50,216,875
Ensembl chr17:49,922,164...50,216,875

G

kirre like nephrin family adhesion molecule 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KIRREL2 mRNA

NCBI chr 7:30,146,955...30,160,105
Ensembl chr 7:30,146,959...30,157,115

G

KiSS-1 metastasis-suppressor

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KISS1 mRNA

NCBI chr 1:133,249,625...133,257,460
Ensembl chr 1:133,237,565...133,257,460
Ensembl chr 1:133,237,565...133,257,460

G

KISS1 receptor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KISS1R mRNA

NCBI chr10:79,752,786...79,759,922
Ensembl chr10:79,752,805...79,758,107

G

KIT proto-oncogene receptor tyrosine kinase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KIT protein

NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382

G

klotho

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KL mRNA

NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282

G

kinesin light chain 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KLC3 mRNA

NCBI chr 7:19,128,365...19,138,101
Ensembl chr 7:19,128,362...19,138,029

G

Kruppel-like transcription factor 10

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of KLF10 mRNA

NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950

G

Kruppel-like transcription factor 11

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of KLF11 mRNA

NCBI chr12:24,701,370...24,712,781
Ensembl chr12:24,701,273...24,712,788

G

Kruppel-like transcription factor 14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of KLF14 mRNA

NCBI chr 6:30,932,956...30,935,925
Ensembl chr 6:30,932,958...30,936,013

G

Kruppel-like transcription factor 15

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KLF15 mRNA

NCBI chr 6:90,437,785...90,468,785
Ensembl chr 6:90,439,558...90,452,220

G

kelch domain containing 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KLHDC4 mRNA

NCBI chr 8:122,523,047...122,556,322
Ensembl chr 8:122,523,052...122,556,308

G

kelch domain containing 8A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KLHDC8A mRNA

NCBI chr 1:132,226,352...132,236,216
Ensembl chr 1:132,226,364...132,235,095

G

kelch-like 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KLHL3 mRNA

NCBI chr13:58,148,040...58,271,288
Ensembl chr13:58,148,042...58,261,406

G

kallikrein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KLK1 mRNA

NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042

G

killer cell lectin-like receptor subfamily A, member 13, pseudogene

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KLRA13-PS mRNA

NCBI chr 6:130,268,124...130,283,395
Ensembl chr 6:130,268,124...130,283,391

G

killer cell lectin-like receptor, subfamily A, member 17

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KLRA17 mRNA

NCBI chr 6:129,808,117...129,853,635
Ensembl chr 6:129,808,117...129,853,635

G

killer cell lectin-like receptor, subfamily A, member 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KLRA6 mRNA

NCBI chr 6:129,989,993...130,003,917
Ensembl chr 6:129,989,996...130,003,917

G

kynurenine 3-monooxygenase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of KMO mRNA

NCBI chr 1:175,459,759...175,488,419
Ensembl chr 1:175,447,947...175,489,682

G

kinase non-catalytic C-lobe domain (KIND) containing 1

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KNDC1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KNDC1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of KNDC1 mRNA

PMID:22401849 PMID:36189433

NCBI chr 7:139,474,612...139,521,453
Ensembl chr 7:139,474,612...139,521,450

G

kringle containing transmembrane protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KREMEN2 mRNA

NCBI chr17:23,960,173...23,965,305
Ensembl chr17:23,960,171...23,964,807

G

keratin 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KRT1 mRNA

NCBI chr15:101,753,861...101,759,221
Ensembl chr15:101,753,861...101,759,229

G

keratin 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of KRT15 mRNA

NCBI chr11:100,022,585...100,026,775
Ensembl chr11:100,022,584...100,026,754

G

keratin 17

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of KRT17 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KRT17 mRNA

NCBI chr11:100,147,041...100,151,855
Ensembl chr11:100,147,043...100,151,855

G

keratin 19

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of KRT19 mRNA

NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491

G

keratin 34

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of KRT34 mRNA

NCBI chr11:99,928,173...99,932,380
Ensembl chr11:99,928,173...99,932,380

G

keratin 42

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of KRT42 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KRT42 mRNA

NCBI chr11:100,153,708...100,160,777
Ensembl chr11:100,153,708...100,160,697

G

kyphoscoliosis peptidase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of KY mRNA

NCBI chr 9:102,382,954...102,423,443
Ensembl chr 9:102,382,949...102,423,438

G

laminin, alpha 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LAMA3 mRNA

NCBI chr18:12,466,806...12,716,070
Ensembl chr18:12,466,876...12,716,070

G

laminin, alpha 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LAMA4 mRNA

NCBI chr10:38,841,511...38,986,184
Ensembl chr10:38,841,511...38,986,184

G

laminin, gamma 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of LAMC2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LAMC2 mRNA

PMID:36189433 PMID:36695872

NCBI chr 1:152,998,502...153,062,193
Ensembl chr 1:152,998,502...153,062,193

G

lysosomal-associated membrane protein family, member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LAMP5 mRNA

NCBI chr 2:135,893,945...135,911,837
Ensembl chr 2:135,894,159...135,911,837

G

LARGE xylosyl- and glucuronyltransferase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LARGE2 mRNA

NCBI chr 2:92,195,391...92,201,437
Ensembl chr 2:92,195,391...92,205,214

G

La ribonucleoprotein 6, translational regulator

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LARP6 mRNA

NCBI chr 9:60,620,404...60,646,084
Ensembl chr 9:60,620,272...60,646,084

G

large tumor suppressor

multiple interactions

LATS1 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased stability of YAP1 protein]

NCBI chr10:7,556,964...7,592,225
Ensembl chr10:7,556,978...7,592,224

G

limb-bud and heart

affects expression
decreases expression

mono-(2-ethylhexyl)phthalate affects the expression of LBH mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of LBH mRNA

PMID:21195148 PMID:36695872

NCBI chr17:73,225,300...73,248,941
Ensembl chr17:73,225,300...73,248,942

G

LBH domain containing 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LBHD2 mRNA

NCBI chr12:111,368,485...111,378,526
Ensembl chr12:111,373,243...111,378,524

G

lymphocyte cytosolic protein 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LCP1 mRNA

NCBI chr14:75,368,570...75,468,282
Ensembl chr14:75,368,541...75,468,282

G

lactate dehydrogenase A

multiple interactions
increases secretion

L 709049 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of LDHA protein]

NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051

G

low density lipoprotein receptor class A domain containing 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LDLRAD4 mRNA

NCBI chr18:68,065,345...68,393,621
Ensembl chr18:68,066,328...68,401,701

G

left right determination factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LEFTY1 mRNA

NCBI chr 1:180,762,587...180,765,966
Ensembl chr 1:180,762,587...180,765,965

G

leptin

decreases secretion

mono-(2-ethylhexyl)phthalate results in decreased secretion of LEP protein

NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876

G

leptin receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LEPR mRNA

NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549

G

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LFNG mRNA

NCBI chr 5:140,593,096...140,601,300
Ensembl chr 5:140,593,075...140,601,300

G

lectin, galactose binding, soluble 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LGALS7 mRNA

NCBI chr 7:28,563,258...28,565,711
Ensembl chr 7:28,563,278...28,565,709

G

leucine-rich repeat LGI family, member 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LGI1 mRNA

NCBI chr19:38,253,135...38,297,387
Ensembl chr19:38,252,984...38,300,662

G

legumain

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LGMN mRNA

NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072

G

leucine-rich repeat-containing G protein-coupled receptor 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LGR4 mRNA

NCBI chr 2:109,747,919...109,844,602
Ensembl chr 2:109,747,992...109,844,602

G

leucine rich repeat containing G protein coupled receptor 5

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of LGR5 mRNA

NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685

G

luteinizing hormone beta

multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased secretion of Testosterone]
mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased expression of STAR protein]; mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased secretion of Progesterone]
mono-(2-ethylhexyl)phthalate results in decreased expression of LHB mRNA

PMID:19440488 PMID:34627990 PMID:34954075

NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321

G

luteinizing hormone/choriogonadotropin receptor

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of LHCGR mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of LHCGR mRNA

PMID:22401849 PMID:31884101

NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418

G

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

affects expression
decreases expression

mono-(2-ethylhexyl)phthalate affects the expression of LHPP mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of LHPP mRNA

PMID:21195148 PMID:36314267

NCBI chr 7:132,212,344...132,308,149
Ensembl chr 7:132,212,367...132,308,149

G

LIM homeobox protein 1

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LHX1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of LHX1 mRNA

NCBI chr11:84,408,801...84,416,360
Ensembl chr11:84,409,110...84,416,361

G

LIM homeobox protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LHX2 mRNA

NCBI chr 2:38,229,282...38,259,747
Ensembl chr 2:38,229,293...38,259,745

G

LIM domain and actin binding 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LIMA1 mRNA

NCBI chr15:99,676,351...99,773,292
Ensembl chr15:99,676,351...99,773,337

G

LIM and senescent cell antigen like domains 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LIMS2 mRNA

NCBI chr18:32,055,346...32,091,673
Ensembl chr18:32,055,343...32,091,672

G

lin-7 homolog A, crumbs cell polarity complex component

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LIN7A mRNA

NCBI chr10:107,107,410...107,261,007
Ensembl chr10:107,107,547...107,257,335

G

lin-7 homolog B, crumbs cell polarity complex component

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LIN7B mRNA

NCBI chr 7:45,017,315...45,019,988
Ensembl chr 7:45,017,315...45,020,007

G

lysosomal acid lipase A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LIP1 mRNA

NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874

G

lipase, hormone sensitive

increases expression
multiple interactions
increases phosphorylation

mono-(2-ethylhexyl)phthalate results in increased expression of LIPE mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of LIPE mRNA; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of LIPE protein]

PMID:25543134 PMID:27181934 PMID:30648648

NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135

G

lipase, endothelial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LIPG mRNA

NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334

G

lipase, member H

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LIPH mRNA

NCBI chr16:21,772,567...21,814,408
Ensembl chr16:21,772,567...21,814,413

G

LLGL2 scribble cell polarity complex component

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LLGL2 mRNA

NCBI chr11:115,714,855...115,746,606
Ensembl chr11:115,714,875...115,746,606

G

LIM and cysteine-rich domains 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LMCD1 mRNA

NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386

G

LIM homeobox transcription factor 1 beta

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LMX1B mRNA

NCBI chr 2:33,450,977...33,531,219
Ensembl chr 2:33,450,977...33,530,620

G

leucyl/cystinyl aminopeptidase

multiple interactions

mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of LNPEP protein]

NCBI chr17:17,747,985...17,846,303
Ensembl chr17:17,741,672...17,845,312

G

lysyl oxidase-like 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LOXL2 mRNA

NCBI chr14:69,846,085...69,933,283
Ensembl chr14:69,846,517...69,933,283

G

lysophosphatidic acid receptor 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LPAR3 mRNA

NCBI chr 3:145,926,716...145,991,969
Ensembl chr 3:145,926,718...145,991,941

G

lysophosphatidylcholine acyltransferase 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LPCAT2 mRNA

NCBI chr 8:93,581,948...93,645,907
Ensembl chr 8:93,581,967...93,645,907

G

lysophosphatidylcholine acyltransferase 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LPCAT3 mRNA

NCBI chr 6:124,639,887...124,681,142
Ensembl chr 6:124,639,990...124,681,381

G

lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LRAT mRNA

NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280

G

leucine-rich repeats and immunoglobulin-like domains 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of LRIG1 mRNA

NCBI chr 6:94,581,510...94,677,205
Ensembl chr 6:94,581,510...94,677,139

G

leucine rich repeat containing 18

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC18 mRNA

NCBI chr14:32,713,339...32,737,257
Ensembl chr14:32,713,339...32,737,248

G

leucine rich repeat containing 32

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LRRC32 mRNA

NCBI chr 7:98,138,515...98,151,038
Ensembl chr 7:98,138,490...98,151,388

G

leucine rich repeat containing 36

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC36 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of LRRC36 mRNA

NCBI chr 8:106,140,230...106,190,718
Ensembl chr 8:106,140,203...106,190,718

G

leucine rich repeat containing 3B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC3B mRNA

NCBI chr14:7,030,776...7,112,248
Ensembl chr14:7,030,776...7,112,248

G

leucine rich repeat containing 4

affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate affects the expression of LRRC4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC4 mRNA

PMID:21195148 PMID:36189433

NCBI chr 6:28,828,125...28,831,746
Ensembl chr 6:28,661,830...28,831,746

G

leucine rich repeat containing 4B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC4B mRNA

NCBI chr 7:44,091,911...44,112,775
Ensembl chr 7:44,078,442...44,112,775

G

leucine rich repeat containing 56

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of LRRC56 mRNA

NCBI chr 7:140,774,024...140,789,968
Ensembl chr 7:140,774,070...140,789,968

G

leucine rich repeat containing 66

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LRRC66 mRNA

NCBI chr 5:73,763,985...73,789,771
Ensembl chr 5:73,763,985...73,789,869

G

leucine rich repeat containing 75B

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRC75B mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of LRRC75B mRNA

NCBI chr10:75,385,953...75,396,532
Ensembl chr10:75,385,957...75,396,164

G

leucine rich repeat (in FLII) interacting protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LRRFIP1 mRNA

NCBI chr 1:90,924,652...91,056,666
Ensembl chr 1:90,926,459...91,056,666

G

leucine rich repeat protein 1, neuronal

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRN1 mRNA

NCBI chr 6:107,506,687...107,547,189
Ensembl chr 6:107,506,729...107,547,175

G

leucine rich repeat protein 3, neuronal

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRN3 mRNA

NCBI chr12:41,501,667...41,536,056
Ensembl chr12:41,501,667...41,536,430

G

leucine rich repeat transmembrane neuronal 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LRRTM3 mRNA

NCBI chr10:63,764,276...63,926,034
Ensembl chr10:63,764,251...63,926,056

G

latent transforming growth factor beta binding protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LTBP1 mRNA

NCBI chr17:75,312,475...75,699,507
Ensembl chr17:75,312,563...75,699,507

G

latent transforming growth factor beta binding protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LTBP2 mRNA

NCBI chr12:84,829,986...84,923,581
Ensembl chr12:84,829,986...84,923,306

G

leucine rich adaptor protein 1-like

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LURAP1L mRNA

NCBI chr 4:80,828,923...80,872,538
Ensembl chr 4:80,828,883...80,873,865

G

lymphocyte antigen 6 family member A

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LY6A mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of LY6A mRNA

NCBI chr15:74,866,726...74,869,880
Ensembl chr15:74,866,726...74,869,880

G

lymphocyte antigen 6 family member C1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of LY6C1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of LY6C1 mRNA

NCBI chr15:74,915,867...74,920,690
Ensembl chr15:74,915,867...74,920,679

G

lymphocyte antigen 6 family member G6E

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of LY6G6E mRNA

NCBI chr17:35,295,843...35,297,781
Ensembl chr17:35,295,878...35,297,780

G

lymphocyte antigen 6 family member H

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of LY6H mRNA

NCBI chr15:75,436,594...75,439,114
Ensembl chr15:75,424,894...75,439,104

G

lymphocyte antigen 75

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LY75 mRNA

NCBI chr 2:60,122,447...60,213,617
Ensembl chr 2:60,122,447...60,213,647

G

LY6/PLAUR domain containing 9

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of LYPD9 mRNA

NCBI chr11:58,336,969...58,343,792
Ensembl chr11:58,336,975...58,343,749

G

meiosis 1 associated protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of M1AP mRNA

NCBI chr 6:82,923,889...83,007,290
Ensembl chr 6:82,923,883...83,007,290

G

mab-21-like 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAB21L3 mRNA

NCBI chr 3:101,720,392...101,743,601
Ensembl chr 3:101,720,392...101,756,275

G

MAF bZIP transcription factor A

affects expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate affects the expression of MAFA protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAFA mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of MAFA mRNA

PMID:36189433 PMID:38048874

NCBI chr15:75,617,350...75,620,170
Ensembl chr15:75,617,339...75,620,077

G

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MAFF mRNA

PMID:16809437 PMID:36695872

NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276

G

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MAFK mRNA

NCBI chr 5:139,777,291...139,788,409
Ensembl chr 5:139,777,268...139,788,408

G

myelin-associated glycoprotein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAG mRNA

NCBI chr 7:30,598,600...30,614,347
Ensembl chr 7:30,598,601...30,614,298

G

MAGE family member A10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAGEA10 mRNA

NCBI chr X:71,425,476...71,430,464
Ensembl chr X:71,425,476...71,430,464

G

MAGE family member A14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAGEA14 mRNA

NCBI chr X:51,057,570...51,062,379
Ensembl chr X:51,057,572...51,061,649

G

MAGE family member A5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAGEA5 mRNA

NCBI chr X:153,836,057...153,846,147
Ensembl chr X:153,836,057...153,846,141

G

MAGE family member A9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAGEA9 mRNA

NCBI chr X:63,217,154...63,222,385
Ensembl chr X:63,217,154...63,222,384

G

MAGE family member B17, pseudogene

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAGEB17-PS mRNA

NCBI chr X:90,668,959...90,670,083
Ensembl chr X:90,669,001...90,669,919

G

MAGE family member B18

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MAGEB18 mRNA

NCBI chr X:91,162,485...91,643,178
Ensembl chr X:91,162,485...91,643,178

G

membrane anchored junction protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAJIN mRNA

NCBI chr19:6,234,358...6,274,349
Ensembl chr19:6,234,418...6,274,255

G

male germ cell-associated kinase

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of MAK mRNA

NCBI chr13:41,178,483...41,233,182
Ensembl chr13:41,178,484...41,233,182

G

MEF2 activating motif and SAP domain containing transcriptional regulator

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAMSTR mRNA

NCBI chr 7:45,288,616...45,297,631
Ensembl chr 7:45,289,401...45,295,945

G

monoamine oxidase B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAOB mRNA

NCBI chr X:16,575,520...16,683,605
Ensembl chr X:16,575,521...16,683,605

G

microtubule-associated protein 1B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MAP1B mRNA

NCBI chr13:99,557,972...99,653,110
Ensembl chr13:99,557,954...99,653,048

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased localization of MAP1LC3B protein

NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499

G

microtubule-associated protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAP2 mRNA

NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742

G

mitogen-activated protein kinase kinase 1

decreases phosphorylation
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of MAP2K1 protein
Zinc inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of MAP2K1 protein]

NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913

G

mitogen-activated protein kinase kinase 2

decreases phosphorylation
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of MAP2K2 protein
Zinc inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of MAP2K2 protein]

NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809

G

mitogen-activated protein kinase kinase 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MAP2K6 mRNA

NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348

G

mitogen-activated protein kinase kinase kinase 13

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAP3K13 mRNA

NCBI chr16:21,643,923...21,752,189
Ensembl chr16:21,613,096...21,752,189

G

MAP7 domain containing 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MAP7D3 mRNA

NCBI chr X:55,840,193...55,867,866
Ensembl chr X:55,843,218...55,867,686

G

mitogen-activated protein kinase 1

multiple interactions
increases phosphorylation
affects phosphorylation
decreases phosphorylation

mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK1 protein]
mono-(2-ethylhexyl)phthalate results in increased phosphorylation of MAPK1 protein
mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK1 protein
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of MAPK1 protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK1 protein]; Zinc inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of MAPK1 protein]

PMID:22564763 PMID:28390675 PMID:30810372 PMID:34910997 PMID:35841924 More...

NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317

G

mitogen-activated protein kinase 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAPK11 mRNA

NCBI chr15:89,026,685...89,033,809
Ensembl chr15:89,026,689...89,033,831

G

mitogen-activated protein kinase 3

multiple interactions
increases phosphorylation
affects phosphorylation
decreases phosphorylation

mono-(2-ethylhexyl)phthalate inhibits the reaction [GDNF protein results in increased phosphorylation of MAPK3 protein]
mono-(2-ethylhexyl)phthalate results in increased phosphorylation of MAPK3 protein
mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK3 protein
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of MAPK3 protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A] inhibits the reaction [HDAC6 protein affects the phosphorylation of MAPK3 protein]; Zinc inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of MAPK3 protein]

PMID:22564763 PMID:28390675 PMID:30810372 PMID:34910997 PMID:35841924 More...

NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991

G

mitogen-activated protein kinase 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MAPK4 mRNA

NCBI chr18:74,061,557...74,198,643
Ensembl chr18:74,061,557...74,198,430

G

mitogen-activated protein kinase 8

affects phosphorylation

mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK8 protein

NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115

G

mitogen-activated protein kinase-activated protein kinase 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MAPKAPK3 mRNA

NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076

G

microtubule-associated protein tau

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MAPT mRNA

NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916

G

macrophage receptor with collagenous structure

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MARCO mRNA]

NCBI chr 1:120,402,267...120,432,753
Ensembl chr 1:120,402,267...120,432,753

G

methionine-tRNA synthetase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MARS1 mRNA

NCBI chr10:127,132,090...127,147,655
Ensembl chr10:127,132,090...127,147,655

G

MARVEL (membrane-associating) domain containing 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MARVELD2 mRNA

NCBI chr13:100,732,465...100,753,479
Ensembl chr13:100,732,465...100,753,479

G

MBL associated serine protease 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MASP1 mRNA

NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565

G

matrilin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MATN2 mRNA

NCBI chr15:34,306,827...34,436,388
Ensembl chr15:34,306,823...34,436,419

G

matrilin 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MATN4 mRNA

NCBI chr 2:164,231,313...164,247,080
Ensembl chr 2:164,231,313...164,247,080

G

myoglobin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MB mRNA

NCBI chr15:76,899,687...76,934,868
Ensembl chr15:76,899,687...76,934,870

G

methyl-CpG binding domain protein 3-like 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MBD3L2 mRNA

NCBI chr 9:18,341,911...18,357,612
Ensembl chr 9:18,341,950...18,357,612

G

myelin basic protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MBP mRNA

NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762

G

melanoma cell adhesion molecule

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of MCAM mRNA

NCBI chr 9:44,045,958...44,054,024
Ensembl chr 9:44,045,766...44,054,024

G

mcf.2 transforming sequence

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MCF2 mRNA

NCBI chr X:59,101,316...59,224,546
Ensembl chr X:59,101,316...59,224,449

G

MAM domain containing glycosylphosphatidylinositol anchor 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MDGA1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MDGA1 mRNA

PMID:22401849 PMID:36189433 PMID:36695872

NCBI chr17:30,046,930...30,107,557
Ensembl chr17:30,046,923...30,189,061

G

transformed mouse 3T3 cell double minute 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MDM2 protein

NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663

G

malic enzyme 3, NADP(+)-dependent, mitochondrial

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ME3 mRNA

NCBI chr 7:89,281,492...89,503,423
Ensembl chr 7:89,281,600...89,503,567

G

mediator complex subunit 1

multiple interactions

mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to MED1 protein]

NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119

G

multiple EGF-like-domains 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEGF11 mRNA

NCBI chr 9:64,291,556...64,618,584
Ensembl chr 9:64,292,908...64,616,487

G

meiotic double-stranded break formation protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEI1 mRNA

NCBI chr15:81,954,275...82,011,018
Ensembl chr15:81,954,197...82,011,015

G

meiotic double-stranded break formation protein 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEI4 mRNA

NCBI chr 9:81,745,723...82,088,060
Ensembl chr 9:81,745,723...82,088,060

G

meiosis specific with coiled-coil domain

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEIOC mRNA

NCBI chr11:102,556,177...102,573,066
Ensembl chr11:102,554,542...102,573,063

G

mesenchyme homeobox 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MEOX1 mRNA

NCBI chr11:101,768,336...101,785,309
Ensembl chr11:101,768,336...101,785,200

G

meprin 1 beta

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MEP1B mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MEP1B mRNA

PMID:22401849 PMID:36189433

NCBI chr18:21,205,401...21,233,256
Ensembl chr18:21,194,980...21,233,256

G

mesoderm posterior 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MESP2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MESP2 mRNA

PMID:31711903 PMID:36189433

NCBI chr 7:79,460,475...79,463,179
Ensembl chr 7:79,460,475...79,463,187

G

mesoderm specific transcript

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MEST mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MEST mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:30,733,505...30,783,580
Ensembl chr 6:30,723,546...30,748,464

G

methyltransferase 14, N6-adenosine-methyltransferase subunit

multiple interactions
decreases expression
increases expression

METTL14 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [METTL14 protein affects the expression of SCARB1 mRNA]
mono-(2-ethylhexyl)phthalate results in decreased expression of METTL14 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of METTL14 protein
mono-(2-ethylhexyl)phthalate results in increased expression of METTL14 mRNA

PMID:31875672 PMID:36174712

NCBI chr 3:123,161,944...123,179,639
Ensembl chr 3:123,161,946...123,179,757

G

methyltransferase 16, N6-methyladenosine

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of METTL16 mRNA

NCBI chr11:74,661,658...74,716,649
Ensembl chr11:74,661,656...74,719,351

G

methyltransferase like 24

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of METTL24 mRNA

NCBI chr10:40,558,447...40,687,080
Ensembl chr10:40,559,278...40,687,079

G

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

decreases expression
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of METTL3 mRNA
METTL3 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased methylation of HMBOX1 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of METTL3 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of METTL3 protein

PMID:31875672 PMID:36174712

NCBI chr14:52,532,298...52,548,555
Ensembl chr14:52,532,298...52,542,585

G

methyltransferase 4, N6-adenosine

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of METTL4 mRNA

NCBI chr17:95,030,018...95,057,579
Ensembl chr17:95,030,018...95,057,447

G

mitochondrial fission factor

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MFF mRNA

NCBI chr 1:82,702,599...82,730,111
Ensembl chr 1:82,702,611...82,730,115

G

mitofusin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MFN2 mRNA

NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161

G

major facilitator superfamily domain containing 13a

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MFSD13A mRNA

NCBI chr19:46,345,315...46,363,693
Ensembl chr19:46,329,560...46,363,691

G

mitochondria localized glutamic acid rich protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MGARP mRNA

NCBI chr 3:51,295,833...51,303,968
Ensembl chr 3:51,295,833...51,304,159

G

MGAT4 family, member C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MGAT4C mRNA

NCBI chr10:101,517,348...102,227,712
Ensembl chr10:101,517,348...102,227,330

G

monoglyceride lipase

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of MGLL mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MGLL mRNA

PMID:36189433 PMID:36695872

NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342

G

microsomal glutathione S-transferase 2

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MGST2 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of MGST2 mRNA

PMID:22401849 PMID:38113427

NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MICAL2 mRNA

NCBI chr 7:111,825,032...112,012,311
Ensembl chr 7:111,825,063...112,012,313

G

midline 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MID1 mRNA

NCBI chr X:168,468,178...168,773,692
Ensembl chr X:168,468,195...168,773,794

G

macrophage migration inhibitory factor (glycosylation-inhibiting factor)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIF protein

NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074

G

membrane integral NOTCH2 associated receptor 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MINAR1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MINAR1 mRNA

NCBI chr 9:89,469,261...89,505,940
Ensembl chr 9:89,469,269...89,505,178

G

myo-inositol oxygenase

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MIOX mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of MIOX mRNA

NCBI chr15:89,218,676...89,221,210
Ensembl chr15:89,218,601...89,221,218

G

microRNA 101a

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIR101A mRNA

NCBI chr 4:101,204,142...101,204,224
Ensembl chr 4:101,204,142...101,204,224

G

microRNA 106b

multiple interactions

[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which affects the expression of MIR106B

NCBI chr 5:138,163,999...138,164,080
Ensembl chr 5:138,163,999...138,164,080

G

microRNA 141

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of MIR141 mRNA

NCBI chr 6:124,694,877...124,694,948
Ensembl chr 6:124,694,877...124,694,948

G

microRNA 15b

multiple interactions

[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which affects the expression of MIR15B

NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168

G

microRNA 16-1

multiple interactions
increases expression

MIR16-1 mRNA affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of BCL2 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of MIR16-1 mRNA

PMID:26597031 PMID:31875672

NCBI chr14:61,869,329...61,869,421
Ensembl chr14:61,869,329...61,869,421

G

microRNA 184

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MIR184 mRNA

NCBI chr 9:89,684,313...89,684,381
Ensembl chr 9:89,684,313...89,684,381

G

microRNA 202

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MIR202 mRNA

NCBI chr 7:139,537,602...139,537,673
Ensembl chr 7:139,537,602...139,537,673

G

microRNA 208b

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MIR208B mRNA

NCBI chr14:55,213,157...55,213,233
Ensembl chr14:55,213,157...55,213,233

G

microRNA 27b

multiple interactions
decreases expression

MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein]; MYC protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MIR27B mRNA]

NCBI chr13:63,448,526...63,448,598
Ensembl chr13:63,448,526...63,448,598

G

microRNA 291b

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MIR372 mRNA
MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein]

NCBI chr 7:3,268,156...3,268,234
Ensembl chr 7:3,268,156...3,268,234

G

microRNA 362

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIR362 mRNA

NCBI chr X:7,108,221...7,108,285
Ensembl chr X:7,108,221...7,108,285

G

microRNA 501

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIR501 mRNA

NCBI chr X:7,107,482...7,107,590
Ensembl chr X:7,107,482...7,107,590

G

microRNA 532

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIR532 mRNA

NCBI chr X:7,114,641...7,114,736
Ensembl chr X:7,114,641...7,114,736

G

microRNA 542

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIR542 mRNA

NCBI chr X:52,138,280...52,138,364
Ensembl chr X:52,138,280...52,138,364

G

MIR670 host gene (non-protein coding)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MIR670HG mRNA

NCBI chr 2:93,990,981...94,095,446
Ensembl chr 2:93,990,980...94,095,374

G

microRNA 877

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MIR877 mRNA

NCBI chr17:36,271,622...36,271,706
Ensembl chr17:36,271,622...36,271,706

G

MISP family member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MISP3 mRNA

NCBI chr 8:84,736,857...84,738,349
Ensembl chr 8:84,736,851...84,738,800

G

Mix paired-like homeobox

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MIXL1 mRNA

NCBI chr 1:180,520,608...180,524,599
Ensembl chr 1:180,520,608...180,524,599

G

antigen identified by monoclonal antibody Ki 67

multiple interactions
increases expression

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of MKI67 mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of MKI67 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of MKI67 protein

PMID:31884101 PMID:35861251 PMID:36314267

NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090

G

melan-A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MLANA mRNA

NCBI chr19:29,674,956...29,685,847
Ensembl chr19:29,675,224...29,686,034

G

malonyl-CoA decarboxylase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MLYCD mRNA

NCBI chr 8:120,121,591...120,148,577
Ensembl chr 8:120,121,617...120,137,841

G

membrane metallo-endopeptidase-like 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MMEL1 mRNA

NCBI chr 4:154,954,042...154,979,987
Ensembl chr 4:154,954,042...154,979,985

G

matrix metallopeptidase 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MMP15 mRNA

NCBI chr 8:96,078,924...96,100,921
Ensembl chr 8:96,078,896...96,101,708

G

matrix metallopeptidase 19

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MMP19 mRNA

NCBI chr10:128,626,779...128,636,696
Ensembl chr10:128,626,779...128,636,693

G

matrix metallopeptidase 1b (interstitial collagenase)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MMP1 mRNA

NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047

G

matrix metallopeptidase 2

increases expression
increases activity
increases secretion
multiple interactions
affects expression

mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 protein
mono-(2-ethylhexyl)phthalate results in increased activity of MMP2 protein
mono-(2-ethylhexyl)phthalate results in increased secretion of MMP2 protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 protein]; [SB 3CT compound results in decreased activity of MMP2 protein] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of MMP2 protein]; [SB 3CT compound results in decreased activity of MMP2 protein] which results in decreased susceptibility to mono-(2-ethylhexyl)phthalate; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP2 mRNA]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP2 mRNA]; SB 3CT compound inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of MMP2 protein]

PMID:22321834 PMID:28390675 PMID:33631300

NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048

G

matrix metallopeptidase 23

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MMP23B mRNA

NCBI chr 4:155,735,111...155,738,982
Ensembl chr 4:155,735,112...155,737,841

G

matrix metallopeptidase 9

multiple interactions
increases expression
decreases expression
affects expression

2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 protein]; [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in increased secretion of MMP9 protein; ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of MMP9 mRNA]; Fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA]; mifobate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MMP9 protein
mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of MMP9 mRNA]

PMID:28390675 PMID:28416457 PMID:29718165 PMID:30398665 PMID:33631300

NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770

G

myeloid nuclear differentiation antigen like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MNDAL mRNA

NCBI chr 1:173,684,786...173,708,038
Ensembl chr 1:173,676,692...173,708,447

G

myelin-associated oligodendrocytic basic protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MOBP mRNA

NCBI chr 9:119,978,740...120,010,554
Ensembl chr 9:119,978,773...120,010,550

G

Mov10 like RISC complex RNA helicase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MOV10L1 mRNA

NCBI chr15:88,867,094...88,939,355
Ensembl chr15:88,867,112...88,939,355

G

monooxygenase, DBH-like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MOXD1 mRNA

NCBI chr10:24,099,415...24,178,681
Ensembl chr10:24,099,415...24,178,688

G

myeloperoxidase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MPO mRNA

NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239

G

myelin protein zero-like 2

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MPZL2 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of MPZL2 mRNA

NCBI chr 9:44,951,595...44,965,341
Ensembl chr 9:44,951,097...44,965,313

G

melanocortin 2 receptor accessory protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MRAP2 mRNA

NCBI chr 9:87,026,293...87,066,104
Ensembl chr 9:87,026,359...87,066,098

G

mannose receptor, C type 1

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-benzyl phthalate co-treated with monobutyl phthalate] results in decreased expression of MRC1 mRNA

NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868

G

maestro heat-like repeat family member 2B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MROH2B mRNA

NCBI chr15:4,927,697...4,991,689
Ensembl chr15:4,928,219...4,991,687

G

maestro heat-like repeat family member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MROH5 mRNA

NCBI chr15:73,658,785...73,711,520
Ensembl chr15:73,631,916...73,711,548

G

membrane-spanning 4-domains, subfamily A, member 4A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MS4A4A mRNA

NCBI chr19:11,352,827...11,370,682
Ensembl chr19:11,352,887...11,370,154

G

musculin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MSC mRNA

NCBI chr 1:14,823,570...14,826,216
Ensembl chr 1:14,823,570...14,826,216

G

NADH dehydrogenase 1, mitochondrial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ND1 mRNA

NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707

G

metallothionein 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of MT1 mRNA

NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955

G

metallothionein 2

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of MT2 mRNA

NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196

G

metallothionein 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MT3 mRNA

NCBI chr 8:94,879,235...94,880,776
Ensembl chr 8:94,879,235...94,880,774

G

myotubularin related protein 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MTMR7 mRNA

NCBI chr 8:41,003,184...41,088,210
Ensembl chr 8:41,004,136...41,087,840

G

mechanistic target of rapamycin kinase

multiple interactions
increases phosphorylation

epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of MTOR protein]

NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140

G

mitochondrial tumor suppressor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MTUS1 mRNA

NCBI chr 8:41,443,949...41,587,318
Ensembl chr 8:41,443,951...41,586,763

G

mucin 1, transmembrane

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MUC1 mRNA

NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688

G

mucin 13, epithelial transmembrane

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MUC13 mRNA

NCBI chr16:33,614,407...33,640,299
Ensembl chr16:33,614,407...33,640,304

G

mucin 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MUC4 mRNA

NCBI chr16:32,555,089...32,602,786
Ensembl chr16:32,555,015...32,602,754

G

mucin 5, subtype B, tracheobronchial

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MUC5B mRNA

NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821

G

murinoglobulin, pseudogene 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MUG-PS1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MUG-PS1 mRNA

NCBI chr 6:122,153,012...122,225,525
Ensembl chr 6:122,153,073...122,225,065

G

murinoglobulin 2

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MUG2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of MUG2 mRNA

NCBI chr 6:121,983,688...122,062,927
Ensembl chr 6:121,983,720...122,062,924

G

major urinary protein 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MUP4 mRNA

NCBI chr 4:59,956,804...59,960,667
Ensembl chr 4:59,956,804...59,960,710

G

mevalonate (diphospho) decarboxylase

decreases expression
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MVD mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MVD mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of MVD mRNA

PMID:22401849 PMID:36189433

NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161

G

MX dynamin-like GTPase 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MX2 mRNA

NCBI chr16:97,337,281...97,362,101
Ensembl chr16:97,336,508...97,362,100

G

myosin binding protein C, fast-type

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MYBPC2 mRNA

NCBI chr 7:44,151,123...44,174,093
Ensembl chr 7:44,151,123...44,174,080

G

myosin binding protein H-like

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MYBPHL mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of MYBPHL mRNA

NCBI chr 3:108,272,227...108,287,373
Ensembl chr 3:108,272,227...108,287,373

G

myelocytomatosis oncogene

affects localization
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate affects the localization of MYC protein
mono-(2-ethylhexyl)phthalate results in increased expression of MYC mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of MYC protein
[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein]; MYC protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MIR27B mRNA]; tubastatin A inhibits the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of MYC protein]

PMID:21832167 PMID:22321834 PMID:30858031 PMID:34910997

NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223

G

MYCBP associated protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MYCBPAP mRNA

NCBI chr11:94,392,173...94,423,219
Ensembl chr11:94,392,173...94,412,568

G

v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MYCN mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of MYCN mRNA

PMID:16809437 PMID:36314267

NCBI chr12:12,986,094...12,991,837
Ensembl chr12:12,986,094...12,991,915

G

myosin, heavy polypeptide 1, skeletal muscle, adult

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MYH1 mRNA

NCBI chr11:67,090,922...67,115,401
Ensembl chr11:67,090,878...67,115,401

G

myosin, heavy polypeptide 8, skeletal muscle, perinatal

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MYH8 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MYH8 mRNA

PMID:22401849 PMID:36189433

NCBI chr11:67,167,950...67,199,460
Ensembl chr11:67,167,950...67,199,460

G

myosin, light polypeptide kinase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MYLK mRNA

NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790

G

myosin, light polypeptide kinase 2, skeletal muscle

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of MYLK2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MYLK2 mRNA

NCBI chr 2:152,753,265...152,764,985
Ensembl chr 2:152,753,272...152,764,988

G

myosin light chain kinase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MYLK3 mRNA

NCBI chr 8:86,050,933...86,112,969
Ensembl chr 8:86,050,932...86,112,974

G

myosin XVA

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MYO15A mRNA

NCBI chr11:60,360,165...60,419,195
Ensembl chr11:60,360,165...60,419,195

G

myosin VI

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MYO6 mRNA

NCBI chr 9:80,072,262...80,219,011
Ensembl chr 9:80,072,313...80,219,011

G

myosin VIIA

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of MYO7A mRNA

NCBI chr 7:97,700,261...97,768,730
Ensembl chr 7:97,700,267...97,768,731

G

myosin VIIB

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of MYO7B mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MYO7B mRNA

NCBI chr18:32,092,287...32,169,984
Ensembl chr18:32,092,287...32,170,014

G

myoferlin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of MYOF mRNA

NCBI chr19:37,887,484...38,032,025
Ensembl chr19:37,887,484...38,032,025

G

myomesin family, member 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of MYOM3 mRNA

NCBI chr 4:135,486,688...135,542,882
Ensembl chr 4:135,487,026...135,542,875

G

myozenin 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of MYOZ2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MYOZ2 mRNA

NCBI chr 3:122,799,855...122,828,649
Ensembl chr 3:122,799,855...122,828,664

G

myosin VIIA and Rab interacting protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MYRIP mRNA

NCBI chr 9:120,132,996...120,305,167
Ensembl chr 9:120,130,579...120,303,907

G

N(alpha)-acetyltransferase 11, NatA catalytic subunit

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NAA11 mRNA

NCBI chr 5:97,530,068...97,540,189
Ensembl chr 5:97,530,057...97,540,238

G

N-acylethanolamine acid amidase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NAAA mRNA

NCBI chr 5:92,405,519...92,426,040
Ensembl chr 5:92,405,518...92,426,029

G

N-acetylglutamate synthase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NAGS mRNA

NCBI chr11:102,036,339...102,040,354
Ensembl chr11:102,036,339...102,040,303

G

NLR family, apoptosis inhibitory protein 5

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NAIP5 mRNA

NCBI chr13:100,348,243...100,387,437
Ensembl chr13:100,348,247...100,382,831

G

sodium leak channel, non-selective

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NALCN mRNA

NCBI chr14:123,514,046...123,864,846
Ensembl chr14:123,514,046...123,864,556

G

NALCN channel auxiliary factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM155A mRNA

NCBI chr 8:9,256,006...9,823,329
Ensembl chr 8:9,255,902...9,821,161

G

Nanog homeobox

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NANOG protein

NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592

G

nanos C2HC-type zinc finger 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NANOS2 mRNA

NCBI chr 7:18,721,449...18,722,887
Ensembl chr 7:18,721,325...18,722,887

G

nanos C2HC-type zinc finger 3

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of NANOS3 protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NANOS3 mRNA

PMID:36189433 PMID:37364752

NCBI chr 8:84,900,359...84,911,396
Ensembl chr 8:84,900,360...84,911,846

G

neurobeachin-like 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NBEAL2 mRNA

NCBI chr 9:110,453,857...110,483,229
Ensembl chr 9:110,453,857...110,483,229

G

neurocan

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NCAN mRNA

NCBI chr 8:70,545,735...70,573,494
Ensembl chr 8:70,545,735...70,573,523

G

Ncbp2 antisense 2 (head to head)

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of NCBP2AS2 mRNA

NCBI chr16:31,765,868...31,767,323
Ensembl chr16:31,765,868...31,767,312

G

nuclear receptor coactivator 1

multiple interactions

mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H2 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H3 protein]

NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182

G

nuclear receptor coactivator 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NCOA3 mRNA

NCBI chr 2:165,834,557...165,915,162
Ensembl chr 2:165,834,556...165,915,162

G

nuclear receptor coactivator 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NCOA4 mRNA

NCBI chr14:31,881,884...31,901,210
Ensembl chr14:31,881,822...31,901,812

G

nuclear receptor coactivator 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NCOA7 mRNA

NCBI chr10:30,521,578...30,683,401
Ensembl chr10:30,504,995...30,679,322

G

nuclear receptor co-repressor 1

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [PPARA protein binds to NCOR1 protein]

NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367

G

neuron-derived neurotrophic factor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NDNF mRNA

NCBI chr 6:65,648,595...65,689,307
Ensembl chr 6:65,648,574...65,689,310

G

Norrie disease (pseudoglioma) (human)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NDP mRNA

NCBI chr X:16,751,760...16,778,013
Ensembl chr X:16,751,760...16,778,013

G

N-myc downstream regulated gene 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of NDRG1 mRNA

NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489

G

NADH:ubiquinone oxidoreductase subunit A3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFA3 mRNA

NCBI chr 7:3,620,372...3,623,162
Ensembl chr 7:3,620,372...3,623,326

G

NADH:ubiquinone oxidoreductase subunit A6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFA6 mRNA

NCBI chr15:82,234,342...82,238,438
Ensembl chr15:82,234,341...82,238,523

G

NADH:ubiquinone oxidoreductase subunit A7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFA7 mRNA

NCBI chr17:34,043,546...34,057,290
Ensembl chr17:34,043,546...34,057,291

G

NADH:ubiquinone oxidoreductase complex assembly factor 6

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NDUFAF6 mRNA

NCBI chr 4:11,048,991...11,076,393
Ensembl chr 4:11,051,045...11,076,205

G

NADH:ubiquinone oxidoreductase subunit B11B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NDUFB11B mRNA

NCBI chr15:81,864,741...81,865,764
Ensembl chr15:81,864,741...81,865,764

G

NADH:ubiquinone oxidoreductase core subunit S5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NDUFS5 mRNA

NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995

G

nebulin

affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate affects the expression of NEB mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NEB mRNA

PMID:22401849 PMID:36189433

NCBI chr 2:52,026,652...52,228,810
Ensembl chr 2:52,026,659...52,268,486

G

nectin cell adhesion molecule 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NECTIN4 mRNA

NCBI chr 1:171,197,741...171,215,855
Ensembl chr 1:171,197,667...171,216,166

G

NIMA (never in mitosis gene a)-related expressed kinase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NEK1 mRNA

NCBI chr 8:61,446,184...61,584,383
Ensembl chr 8:61,446,229...61,584,380

G

neuraminidase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NEU3 mRNA

NCBI chr 7:99,460,646...99,477,579
Ensembl chr 7:99,460,646...99,477,624

G

neuralized E3 ubiquitin protein ligase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NEURL3 mRNA

NCBI chr 1:36,303,683...36,313,755
Ensembl chr 1:36,303,678...36,313,760

G

neurogenin 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NEUROG2 mRNA

NCBI chr 3:127,426,382...127,429,285
Ensembl chr 3:127,426,784...127,429,280

G

nuclear factor, erythroid derived 2, like 2

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NFE2L2 protein
Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFE2L2 protein]; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFE2L2 protein]
mono-(2-ethylhexyl)phthalate results in decreased expression of NFE2L2 protein
RSL3 compound promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of NFE2L2 protein]

PMID:36438553 PMID:37286014 PMID:37692514

NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985

G

nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

multiple interactions
increases expression

AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFKB1 mRNA]

NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308

G

nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NFKB2 mRNA

NCBI chr19:46,285,478...46,300,839
Ensembl chr19:46,292,759...46,300,824

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NFKBIA mRNA

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NFKBIZ mRNA

NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262

G

nerve growth factor

increases response to substance
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased susceptibility to NGF protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NGF mRNA

PMID:21145954 PMID:36189433

NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329

G

Na+/K+ transporting ATPase interacting 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NKAIN2 mRNA

NCBI chr10:31,565,314...32,773,170
Ensembl chr10:31,565,306...32,766,458

G

NK2 homeobox 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NKX2-4 mRNA

NCBI chr 2:146,925,257...146,927,359
Ensembl chr 2:146,925,236...146,927,365

G

neuroligin 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NLGN3 mRNA

NCBI chr X:100,342,785...100,364,956
Ensembl chr X:100,342,774...100,369,569

G

NLR family, pyrin domain containing 12

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NLRP12 mRNA

NCBI chr 7:3,267,317...3,298,400
Ensembl chr 7:3,267,458...3,298,370

G

NLR family, pyrin domain containing 1C, pseudogene

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NLRP1C-PS mRNA

NCBI chr11:71,133,256...71,176,058
Ensembl chr11:71,133,256...71,172,045
Ensembl chr11:71,133,256...71,172,045

G

NLR family, pyrin domain containing 3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein
mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein]; epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein]; Toyocamycin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein]

PMID:31016965 PMID:33159713 PMID:37286014 PMID:37692514

NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782

G

NLR family, pyrin domain containing 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NLRP6 mRNA

NCBI chr 7:140,500,777...140,509,105
Ensembl chr 7:140,500,815...140,509,105

G

NME/NM23 family member 5

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of NME5 mRNA

NCBI chr18:34,695,687...34,712,168
Ensembl chr18:34,695,687...34,712,168

G

NME/NM23 family member 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NME8 mRNA

NCBI chr13:19,829,248...19,881,996
Ensembl chr13:19,829,248...19,881,964

G

NOC4 like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NOC4L mRNA

NCBI chr 5:110,796,285...110,801,248
Ensembl chr 5:110,796,284...110,801,283

G

nodal growth differentiation factor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NODAL mRNA

NCBI chr10:61,253,751...61,261,117
Ensembl chr10:61,253,751...61,261,117

G

nitric oxide synthase 1, neuronal

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NOS1 mRNA

NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905

G

nitric oxide synthase 2, inducible

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]

NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080

G

notch 1

multiple interactions
increases expression

N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH1 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH1 protein
[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased expression of NOTCH1 protein

PMID:36988346 PMID:38042133

NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675

G

notch 2

multiple interactions
increases expression

N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH2 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH2 protein

NCBI chr 3:97,920,854...98,057,683
Ensembl chr 3:97,920,843...98,057,677

G

notch 3

increases expression
affects expression

mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH3 mRNA
mono-(2-ethylhexyl)phthalate affects the expression of NOTCH3 protein

NCBI chr17:32,339,794...32,385,869
Ensembl chr17:32,339,794...32,385,826

G

notch 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of NOTCH4 protein

PMID:36988346 PMID:38042133

NCBI chr17:34,783,257...34,807,517
Ensembl chr17:34,783,242...34,807,477

G

neuronal PAS domain protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NPAS2 mRNA

NCBI chr 1:39,233,013...39,402,321
Ensembl chr 1:39,232,812...39,402,317

G

neuropeptides B/W receptor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NPBWR1 mRNA

NCBI chr 1:5,983,926...5,987,617
Ensembl chr 1:5,983,926...5,987,617

G

NPC1 like intracellular cholesterol transporter 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NPC1L1 mRNA

NCBI chr11:6,161,011...6,180,245
Ensembl chr11:6,161,013...6,180,143

G

nephronophthisis 4 (juvenile) homolog (human)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NPHP4 mRNA

NCBI chr 4:152,561,163...152,647,641
Ensembl chr 4:152,561,163...152,647,640

G

nephrosis 1 homolog, nephrin, opposite strand

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NPHS1OS mRNA

NCBI chr 7:30,161,589...30,165,016
Ensembl chr 7:30,161,589...30,165,016

G

natriuretic peptide type B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NPPB mRNA

NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662

G

neuropeptide Y receptor Y2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NPY2R mRNA

NCBI chr 3:82,445,688...82,455,404
Ensembl chr 3:82,445,690...82,455,391

G

nuclear receptor subfamily 0, group B, member 1

decreases expression
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of NR0B1 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of NR0B1 mRNA
mono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in increased expression of NR0B1 mRNA]
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NR0B1 mRNA

PMID:16809437 PMID:30476341 PMID:36189433

NCBI chr X:85,235,381...85,239,553
Ensembl chr X:85,235,370...85,239,553

G

nuclear receptor subfamily 1, group H, member 2

multiple interactions

mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H2 protein]

NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375

G

nuclear receptor subfamily 1, group H, member 3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of NR1H3 mRNA
mono-(2-ethylhexyl)phthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H3 protein]

PMID:23118965 PMID:27551952

NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179

G

nuclear receptor subfamily 1, group H, member 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NR1H4 mRNA

NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions
increases activity

mono-(2-ethylhexyl)phthalate binds to and results in increased activity of NR1I2 protein
mono-(2-ethylhexyl)phthalate results in increased activity of NR1I2 protein

PMID:16054614 PMID:27551952 PMID:33049310

NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
increases activity

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of NR1I3 mRNA; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of NR1I3 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein]
mono-(2-ethylhexyl)phthalate results in increased activity of NR1I3 protein alternative form

PMID:18832183 PMID:27551952 PMID:31884101

NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270

G

nuclear receptor subfamily 2, group F, member 2

multiple interactions
decreases expression

[Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of NR2F2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of NR2F2 mRNA

NCBI chr 7:70,001,694...70,016,494
Ensembl chr 7:70,001,692...70,016,483

G

nuclear receptor subfamily 4, group A, member 1

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NR4A1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of NR4A1 mRNA

PMID:19822197 PMID:22401849 PMID:23118965

NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676

G

nuclear receptor subfamily 4, group A, member 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NR4A2 mRNA

NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015

G

nuclear receptor subfamily 4, group A, member 3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of NR4A3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NR4A3 mRNA

PMID:19822197 PMID:36189433

NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447

G

nuclear receptor subfamily 5, group A, member 1

multiple interactions

[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of NR5A1 mRNA

NCBI chr 2:38,582,668...38,604,554
Ensembl chr 2:38,582,668...38,604,554

G

nebulin-related anchoring protein

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of NRAP mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NRAP mRNA

PMID:22401849 PMID:36189433

NCBI chr19:56,308,473...56,378,466
Ensembl chr19:56,308,467...56,378,469

G

neuronal cell adhesion molecule

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NRCAM mRNA

NCBI chr12:44,375,568...44,651,977
Ensembl chr12:44,375,668...44,648,747

G

neuronal regeneration related protein

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of NREP mRNA

NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082

G

nuclear respiratory factor 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of NRF1 mRNA

NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457

G

neuregulin 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NRG1 mRNA

NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825

G

neuritin 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NRN1 mRNA

NCBI chr13:36,909,596...36,918,451
Ensembl chr13:36,909,335...36,919,105

G

neuropilin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NRP2 mRNA

NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854

G

neurensin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NRSN2 mRNA

NCBI chr 2:152,210,675...152,218,560
Ensembl chr 2:152,210,675...152,218,558

G

neurexin III

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NRXN3 mRNA

NCBI chr12:88,689,454...90,301,709
Ensembl chr12:88,689,646...90,301,709

G

NAD(P) dependent steroid dehydrogenase-like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NSDHL mRNA

NCBI chr X:71,962,127...72,002,134
Ensembl chr X:71,962,163...72,002,120

G

NOL1/NOP2/Sun domain family, member 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NSUN7 mRNA

NCBI chr 5:66,417,181...66,457,544
Ensembl chr 5:66,417,240...66,455,369

G

neurotrimin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NTM mRNA

NCBI chr 9:28,906,045...29,874,565
Ensembl chr 9:28,906,046...29,874,437

G

N-terminal Xaa-Pro-Lys N-methyltransferase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NTMT1 mRNA

NCBI chr 2:30,697,576...30,713,045
Ensembl chr 2:30,697,838...30,713,045

G

neurotrophic tyrosine kinase, receptor, type 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NTRK2 mRNA

NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784

G

neurotensin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NTS mRNA

NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347

G

neurotensin receptor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NTSR1 mRNA

NCBI chr 2:180,141,769...180,186,772
Ensembl chr 2:180,141,769...180,186,773

G

nucleoporin 210-like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of NUP210L mRNA

NCBI chr 3:90,011,445...90,119,458
Ensembl chr 3:90,011,439...90,119,355

G

nucleoporin 62 C-terminal like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of NUP62CL mRNA

NCBI chr X:138,907,551...138,963,456
Ensembl chr X:138,907,554...138,963,461

G

NUT midline carcinoma, family member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NUTM1 mRNA

NCBI chr 2:112,078,293...112,089,636
Ensembl chr 2:112,078,293...112,089,636

G

nuclear RNA export factor 7

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of NXF7 mRNA

NCBI chr X:134,480,304...134,499,530
Ensembl chr X:134,480,304...134,499,526

G

neurexophilin 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of NXPH4 mRNA

NCBI chr10:127,361,342...127,370,428
Ensembl chr10:127,361,342...127,370,428

G

2'-5' oligoadenylate synthetase 1A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OAS1A mRNA

NCBI chr 5:121,034,319...121,045,588
Ensembl chr 5:121,034,319...121,045,584

G

2'-5' oligoadenylate synthetase 1B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OAS1B mRNA

NCBI chr 5:120,950,700...120,962,228
Ensembl chr 5:120,950,700...120,962,228

G

2'-5' oligoadenylate synthetase 1D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OAS1D mRNA

NCBI chr 5:121,052,881...121,059,711
Ensembl chr 5:121,052,599...121,059,715

G

ornithine aminotransferase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OAT mRNA

NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127

G

ornithine decarboxylase antizyme 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OAZ3 mRNA

NCBI chr 3:94,340,694...94,343,958
Ensembl chr 3:94,339,721...94,351,222

G

occludin

decreases expression
multiple interactions
affects localization

mono-(2-ethylhexyl)phthalate results in decreased expression of OCLN protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of OCLN protein]; mono-(2-ethylhexyl)phthalate results in decreased expression of and results in decreased localization of OCLN protein

PMID:18214902 PMID:29940330 PMID:37941498

NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226

G

outer dynein arm complex subunit 4

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of ODAD4 mRNA

NCBI chr11:100,436,434...100,463,392
Ensembl chr11:100,436,433...100,463,394

G

osteoglycin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of OGN mRNA

NCBI chr13:49,761,491...49,777,977
Ensembl chr13:49,761,522...49,777,977

G

Opa interacting protein 5, opposite strand 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of OIP5-AS1 mRNA

NCBI chr 2:119,424,777...119,431,227
Ensembl chr 2:119,424,757...119,437,983

G

oncoprotein induced transcript 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OIT3 mRNA

NCBI chr10:59,258,782...59,277,601
Ensembl chr10:59,258,780...59,277,600

G

oxidized low density lipoprotein (lectin-like) receptor 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OLR1 mRNA

NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128

G

opioid binding protein/cell adhesion molecule-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OPCML mRNA

NCBI chr 9:27,702,050...28,836,706
Ensembl chr 9:27,702,071...28,836,706

G

opioid receptor, delta 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OPRD1 mRNA

NCBI chr 4:131,834,980...131,872,042
Ensembl chr 4:131,838,037...131,871,797

G

opioid receptor-like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OPRL1 mRNA

NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778

G

opticin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OPTC mRNA

NCBI chr 1:133,824,937...133,837,344
Ensembl chr 1:133,824,937...133,835,737

G

olfactory receptor family 10 subfamily AG member 59

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of OR10AG59 mRNA

NCBI chr 2:87,405,430...87,406,374
Ensembl chr 2:87,404,246...87,407,603

G

olfactory receptor family 2 subfamily AK member 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OR2AK4 mRNA

NCBI chr11:58,642,356...58,650,292
Ensembl chr11:58,643,560...58,650,497

G

olfactory receptor family 2 subfamily AK member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OR2AK5 mRNA

NCBI chr11:58,610,895...58,611,920
Ensembl chr11:58,608,023...58,614,840

G

olfactory receptor family 4 subfamily A member 78

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OR4A78 mRNA

NCBI chr 2:89,497,272...89,498,228
Ensembl chr 2:89,496,214...89,502,280

G

olfactory receptor family 4 subfamily A member 79

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OR4A79 mRNA

NCBI chr 2:89,551,509...89,552,453
Ensembl chr 2:89,549,919...89,555,356

G

olfactory receptor family 5 subfamily M member 3B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OR5M3B mRNA

NCBI chr 2:85,850,984...85,875,152
Ensembl chr 2:85,850,977...85,875,515

G

olfactory receptor family 5 subfamily M member 9B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OR5M9 mRNA

NCBI chr 2:85,905,048...85,906,062
Ensembl chr 2:85,904,336...85,907,538

G

osteoclast associated receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OSCAR mRNA

NCBI chr 7:3,612,812...3,619,156
Ensembl chr 7:3,612,812...3,619,156

G

oxidative stress induced growth inhibitor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OSGIN1 mRNA

NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995

G

odd-skipped related transcription factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OSR1 mRNA

NCBI chr12:9,624,442...9,631,500
Ensembl chr12:9,620,116...9,631,500

G

otoancorin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of OTOA mRNA

NCBI chr 7:120,682,647...120,762,316
Ensembl chr 7:120,680,873...120,762,320

G

otogelin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of OTOG mRNA

NCBI chr 7:45,890,411...45,960,858
Ensembl chr 7:45,890,411...45,960,858

G

ovary testis transcribed

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OTT mRNA

NCBI chr X:147,880,948...147,921,148
Ensembl chr X:147,857,278...147,921,148

G

OTU domain containing 6A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OTUD6A mRNA

NCBI chr X:99,472,514...99,474,859
Ensembl chr X:99,472,619...99,473,491

G

orthodenticle homeobox 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of OTX2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of OTX2 mRNA

NCBI chr14:48,894,238...48,905,101
Ensembl chr14:48,895,134...48,911,276

G

3-oxoacid CoA transferase 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of OXCT1 mRNA

NCBI chr15:4,055,910...4,184,826
Ensembl chr15:4,055,865...4,184,826

G

oxidoreductase NAD-binding domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of OXNAD1 mRNA

NCBI chr14:31,807,301...31,825,160
Ensembl chr14:31,807,331...31,825,159

G

oxytocin receptor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of OXTR mRNA

NCBI chr 6:112,450,646...112,467,800
Ensembl chr 6:112,450,644...112,466,904

G

purinergic receptor P2Y, G-protein coupled, 14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of P2RY14 mRNA

NCBI chr 3:59,022,044...59,060,913
Ensembl chr 3:59,021,276...59,061,039

G

phosphofurin acidic cluster sorting protein 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PACS1 mRNA

NCBI chr19:5,183,714...5,323,138
Ensembl chr19:5,183,186...5,323,147

G

peptidyl arginine deiminase, type II

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PADI2 mRNA

NCBI chr 4:140,633,685...140,679,897
Ensembl chr 4:140,633,655...140,679,897

G

peptidyl arginine deiminase, type VI

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PADI6 mRNA

NCBI chr 4:140,454,666...140,469,954
Ensembl chr 4:140,454,666...140,469,954

G

phenylalanine hydroxylase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PAH mRNA

NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998

G

p21 (RAC1) activated kinase 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PAK7 mRNA

NCBI chr 2:135,923,008...136,229,899
Ensembl chr 2:135,923,024...136,229,887

G

p21 (RAC1) activated kinase 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PAK6 mRNA

NCBI chr 2:118,493,531...118,528,501
Ensembl chr 2:118,493,784...118,528,501

G

protein associated with LIN7 2, MAGUK family member

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of MPP6 mRNA

NCBI chr 6:50,087,206...50,176,134
Ensembl chr 6:50,087,221...50,175,919

G

peptidylglycine alpha-amidating monooxygenase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PAM mRNA

NCBI chr 1:97,748,816...98,023,578
Ensembl chr 1:97,722,839...98,023,371

G

POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of LINC01159 mRNA

NCBI chr 1:42,746,221...42,752,614
Ensembl chr 1:42,746,206...42,752,940

G

pappalysin 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PAPPA2 mRNA

NCBI chr 1:158,539,297...158,788,019
Ensembl chr 1:158,539,297...158,808,060

G

3'-phosphoadenosine 5'-phosphosulfate synthase 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PAPSS2 mRNA

NCBI chr19:32,573,072...32,644,587
Ensembl chr19:32,573,190...32,644,587

G

poly (ADP-ribose) polymerase family, member 14

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PARP14 mRNA

NCBI chr16:35,652,262...35,691,904
Ensembl chr16:35,653,244...35,691,914

G

parvin, beta

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PARVB mRNA

NCBI chr15:84,116,244...84,199,890
Ensembl chr15:84,116,244...84,199,889

G

protein associated with topoisomerase II homolog 2 (yeast)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PATL2 mRNA

NCBI chr 2:121,950,589...122,016,670
Ensembl chr 2:121,950,589...122,016,670

G

paired box 2

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PAX2 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of PAX2 mRNA

NCBI chr19:44,735,040...44,826,708
Ensembl chr19:44,744,484...44,826,310

G

paired box 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PAX3 mRNA

NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771

G

paired box 6

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of PAX6 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PAX6 mRNA

PMID:31711903 PMID:36189433

NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709

G

paired box 8

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PAX8 protein

NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611

G

pre B cell leukemia homeobox 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PBX3 mRNA

NCBI chr 2:34,061,469...34,264,168
Ensembl chr 2:34,061,469...34,263,154

G

protocadherin 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PCDH10 mRNA

NCBI chr 3:45,332,833...45,389,014
Ensembl chr 3:45,332,833...45,390,058

G

protocadherin 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PCDH15 mRNA

NCBI chr10:72,932,003...74,485,663
Ensembl chr10:72,935,174...74,485,569

G

protocadherin 7

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PCDH7 mRNA

NCBI chr 5:57,873,487...58,290,578
Ensembl chr 5:57,875,309...58,290,572

G

protocadherin 8

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PCDH8 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of PCDH8 mRNA

NCBI chr14:80,004,224...80,008,752
Ensembl chr14:80,004,215...80,008,752

G

PC-esterase domain containing 1B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PCED1B mRNA

NCBI chr15:97,143,563...97,283,574
Ensembl chr15:97,144,988...97,283,561

G

PC-esterase domain containing 1C, pseudogene

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PCED1C-PS mRNA

NCBI chr 1:69,416,457...69,417,683
Ensembl chr 1:69,416,480...69,417,230

G

phosphoenolpyruvate carboxykinase 1, cytosolic

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PCK1 mRNA

PMID:27384973 PMID:32522588

NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PCK2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PCK2 protein

PMID:31228551 PMID:36695872

NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699

G

proliferating cell nuclear antigen

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein
ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR27B mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein]; MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA mRNA]; MIR372 mRNA inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PCNA protein]
mono-(2-ethylhexyl)phthalate results in decreased expression of PCNA protein

PMID:30858031 PMID:31351048 PMID:33631300 PMID:37364752 PMID:38048874

NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234

G

pecanex homolog 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PCNX2 mRNA

NCBI chr 8:126,478,243...126,625,056
Ensembl chr 8:126,478,247...126,625,056

G

pecanex homolog 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PCNX3 mRNA

NCBI chr19:5,714,663...5,739,036
Ensembl chr19:5,714,663...5,738,936

G

procollagen C-endopeptidase enhancer protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PCOLCE mRNA

NCBI chr 5:137,603,369...137,609,666
Ensembl chr 5:137,603,365...137,612,046

G

proprotein convertase subtilisin/kexin type 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PCSK2 mRNA

NCBI chr 2:143,388,053...143,658,204
Ensembl chr 2:143,388,076...143,658,205

G

proprotein convertase subtilisin/kexin type 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PCSK7 mRNA

NCBI chr 9:45,817,745...45,843,405
Ensembl chr 9:45,817,795...45,841,024

G

proprotein convertase subtilisin/kexin type 9

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PCSK9 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of PCSK9 mRNA

NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526

G

phosphate cytidylyltransferase 1, choline, alpha isoform

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PCYT1A mRNA

NCBI chr16:32,249,739...32,293,883
Ensembl chr16:32,249,739...32,293,888

G

phosphodiesterase 2A, cGMP-stimulated

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of PDE2A mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PDE2A mRNA

NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026

G

phosphodiesterase 4D, cAMP specific

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PDE4D mRNA

NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995

G

phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PDE6B mRNA

NCBI chr 5:108,536,239...108,579,609
Ensembl chr 5:108,536,257...108,580,263

G

phosphodiesterase 6C, cGMP specific, cone, alpha prime

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PDE6C mRNA

NCBI chr19:38,121,220...38,172,391
Ensembl chr19:38,121,229...38,172,406

G

platelet derived growth factor, alpha

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PDGFA mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of PDGFA mRNA

NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125

G

pyruvate dehydrogenase E1 alpha 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PDHA2 mRNA

NCBI chr 3:140,915,765...140,918,116
Ensembl chr 3:140,915,765...140,918,116

G

protein disulfide isomerase-like, testis expressed

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PDILT mRNA

NCBI chr 7:119,085,809...119,128,259
Ensembl chr 7:119,085,810...119,122,712

G

pyruvate dehydrogenase kinase, isoenzyme 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PDK4 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PDK4 protein

NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309

G

PDZ and LIM domain 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PDLIM2 mRNA

NCBI chr14:70,401,667...70,415,140
Ensembl chr14:70,401,667...70,415,130

G

pancreatic and duodenal homeobox 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PDX1 protein

NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658

G

prodynorphin

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of PDYN mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PDYN mRNA

PMID:36189433 PMID:38113427

NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764

G

PDZ domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PDZK1 mRNA

NCBI chr 3:96,736,772...96,778,242
Ensembl chr 3:96,736,600...96,778,242

G

PDZ domain containing RING finger 4

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PDZRN4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PDZRN4 mRNA

PMID:22401849 PMID:36189433

NCBI chr15:92,294,691...92,669,700
Ensembl chr15:92,294,762...92,669,700

G

phosphatidylethanolamine binding protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PBP mRNA

NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690

G

paternally expressed 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PEG3 mRNA

NCBI chr 7:6,706,891...6,733,443
Ensembl chr 7:6,706,891...6,733,430

G

period circadian clock 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PER2 mRNA

NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046

G

period circadian clock 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PER3 mRNA

NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122

G

PERP, TP53 apoptosis effector

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PERP mRNA

NCBI chr10:18,720,819...18,732,821
Ensembl chr10:18,720,768...18,732,821

G

peroxisomal biogenesis factor 1

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PEX1 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of PEX1 mRNA

PMID:22401849 PMID:32522588

NCBI chr 5:3,646,066...3,687,230
Ensembl chr 5:3,646,066...3,687,232

G

peroxisomal biogenesis factor 16

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PEX16 mRNA

NCBI chr 2:92,205,043...92,211,563
Ensembl chr 2:92,205,021...92,211,562

G

peroxisomal biogenesis factor 19

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PEX19 mRNA

NCBI chr 1:171,954,322...171,964,064
Ensembl chr 1:171,954,322...171,964,060

G

peroxisomal biogenesis factor 5-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PEX5L mRNA

NCBI chr 3:33,002,075...33,197,470
Ensembl chr 3:33,003,557...33,197,396

G

platelet factor 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PF4 mRNA

NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242

G

phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)

multiple interactions

[mono(2-ethyl-5-hydroxyhexyl) phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono(2-ethyl-5-oxohexyl)phthalate co-treated with 2-ethyl-5-carboxypentyl phthalate co-treated with mono-isobutyl phthalate co-treated with mono-benzyl phthalate co-treated with monoethyl phthalate co-treated with monobutyl phthalate] affects the expression of PFAS mRNA

NCBI chr11:68,876,527...68,899,286
Ensembl chr11:68,876,523...68,899,286

G

piggyBac transposable element derived 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PGBD5 mRNA

NCBI chr 8:125,095,788...125,161,230
Ensembl chr 8:125,095,788...125,166,397

G

pyroglutamyl-peptidase I-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PGPEP1L mRNA

NCBI chr 7:67,881,154...67,914,232
Ensembl chr 7:67,886,358...67,913,981

G

progesterone receptor

multiple interactions
increases secretion

Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of PGR protein]

NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612

G

phosphate regulating endopeptidase homolog, X-linked

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PHEX mRNA

NCBI chr X:155,945,071...156,198,282
Ensembl chr X:155,945,071...156,198,308

G

PHD finger protein 11D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PHF11D mRNA

NCBI chr14:59,584,646...59,608,004
Ensembl chr14:59,584,856...59,602,919

G

PHD finger protein 21B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PHF21B mRNA

NCBI chr15:84,669,577...84,740,330
Ensembl chr15:84,669,582...84,740,250

G

pleckstrin homology like domain, family A, member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PHLDA2 mRNA

NCBI chr 7:143,055,282...143,056,882
Ensembl chr 7:143,055,282...143,056,887

G

phytanoyl-CoA hydroxylase interacting protein

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PHYHIP mRNA

NCBI chr14:70,694,957...70,706,266
Ensembl chr14:70,694,916...70,706,272

G

phosphotyrosine interaction domain containing 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PID1 mRNA

NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901

G

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PIK3C2G mRNA

NCBI chr 6:139,591,070...139,915,010
Ensembl chr 6:139,564,219...139,915,010

G

phosphoinositide-3-kinase regulatory subunit 1

multiple interactions
decreases phosphorylation

RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of PIK3R1 protein]

NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725

G

PTEN induced putative kinase 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein]; Toyocamycin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein]

NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618

G

phosphatidylinositol-4-phosphate 5-kinase, type 1 beta

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PIP5K1B mRNA

NCBI chr19:24,272,158...24,533,236
Ensembl chr19:24,272,158...24,533,236

G

paired-Ig-like receptor A11

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PIRA11 mRNA

G

PITPNM family member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PITPNM3 mRNA

NCBI chr11:71,938,354...72,026,715
Ensembl chr11:71,938,354...72,026,604

G

paired-like homeodomain transcription factor 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PITX2 mRNA

NCBI chr 3:128,993,527...129,013,243
Ensembl chr 3:128,993,527...129,013,240

G

paired-like homeodomain transcription factor 3

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PITX3 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of PITX3 mRNA

NCBI chr19:46,123,720...46,136,764
Ensembl chr19:46,124,124...46,136,765

G

piwi-like RNA-mediated gene silencing 4

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PIWIL4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PIWIL4 mRNA

PMID:22401849 PMID:36189433

NCBI chr 9:14,613,072...14,651,968
Ensembl chr 9:14,607,526...14,652,036

G

polycystic kidney and hepatic disease 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PKHD1 mRNA

NCBI chr 1:20,128,003...20,688,306
Ensembl chr 1:20,128,003...20,688,288

G

pyruvate kinase liver and red blood cell

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PKLR mRNA

NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091

G

phospholipase A1 member A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLA1A mRNA

NCBI chr16:38,214,245...38,253,553
Ensembl chr16:38,216,479...38,253,507

G

phospholipase A2, group X

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PLA2G10 mRNA

NCBI chr16:13,532,921...13,548,863
Ensembl chr16:13,532,921...13,548,847

G

phospholipase A2 receptor 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PLA2R1 mRNA

NCBI chr 2:60,247,887...60,383,669
Ensembl chr 2:60,247,887...60,383,652

G

phospholipase A and acyltransferase 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of HRASLS mRNA

NCBI chr16:29,027,883...29,049,283
Ensembl chr16:29,028,447...29,049,283

G

phospholipase A and acyltransferase 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLAAT3 mRNA

NCBI chr19:7,534,824...7,565,914
Ensembl chr19:7,534,824...7,565,910

G

placenta-specific 8

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PLAC8 mRNA

NCBI chr 5:100,699,455...100,720,119
Ensembl chr 5:100,701,591...100,720,111

G

plasminogen activator, tissue

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PLAT mRNA

NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860

G

plasminogen activator, urokinase receptor

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLAUR mRNA

NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393

G

phospholipase B1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PLB1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PLB1 mRNA

PMID:22401849 PMID:36189433

NCBI chr 5:32,390,035...32,521,700
Ensembl chr 5:32,390,052...32,523,864

G

phospholipase C, beta 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PLCB1 mRNA

NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178

G

phospholipase C, beta 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PLCB2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PLCB2 mRNA

PMID:22401849 PMID:36189433

NCBI chr 2:118,535,484...118,559,140
Ensembl chr 2:118,537,998...118,558,919

G

phosphatidylinositol-specific phospholipase C, X domain containing 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PLCXD2 mRNA

NCBI chr16:45,779,624...45,830,776
Ensembl chr16:45,779,626...45,830,581

G

phospholipase D1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLD1 mRNA

NCBI chr 3:27,992,636...28,187,388
Ensembl chr 3:27,992,844...28,187,511

G

pleckstrin homology domain containing, family A member 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PLEKHA7 mRNA

NCBI chr 7:115,722,722...115,907,617
Ensembl chr 7:115,722,720...115,907,611

G

pleckstrin homology domain containing, family B (evectins) member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PLEKHB1 mRNA

NCBI chr 7:100,291,922...100,311,601
Ensembl chr 7:100,292,099...100,311,621

G

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PLEKHG4 mRNA

NCBI chr 8:106,096,272...106,109,492
Ensembl chr 8:106,099,906...106,109,494

G

perilipin 1

increases expression

mono-(2-ethylhexyl)phthalate analog results in increased expression of PLIN1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PLIN1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PLIN1 protein

PMID:25777084 PMID:27384973

NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651

G

perilipin 2

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of PLIN2 mRNA

NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297

G

perilipin 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLIN4 protein

NCBI chr17:56,407,587...56,416,947
Ensembl chr17:56,407,591...56,416,803

G

perilipin 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PLIN5 mRNA

NCBI chr17:56,418,601...56,424,606
Ensembl chr17:56,418,601...56,424,596

G

polo like kinase 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PLK5 mRNA

NCBI chr10:80,192,293...80,201,323
Ensembl chr10:80,192,293...80,201,323

G

plastin 1 (I-isoform)

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of PLS1 mRNA

NCBI chr 9:95,634,695...95,727,359
Ensembl chr 9:95,634,695...95,727,364

G

phospholipid scramblase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLSCR2 mRNA

NCBI chr 9:92,157,655...92,179,805
Ensembl chr 9:92,157,655...92,179,805

G

plexin A2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PLXNA2 mRNA

NCBI chr 1:194,302,020...194,499,177
Ensembl chr 1:194,300,526...194,499,177

G

plexin B3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of PLXNB3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PLXNB3 mRNA

NCBI chr X:72,800,564...72,816,116
Ensembl chr X:72,800,696...72,816,120

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PMAIP1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PMAIP1 protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PMAIP1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of PMAIP1 mRNA

PMID:24706461 PMID:36189433 PMID:36695872

NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636

G

pancreatic lipase related protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PNLIPRP1 mRNA

NCBI chr19:58,717,319...58,732,601
Ensembl chr19:58,717,319...58,732,601

G

phenylethanolamine-N-methyltransferase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PNMT mRNA

NCBI chr11:98,277,449...98,279,006
Ensembl chr11:98,277,276...98,279,007

G

prepronociceptin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PNOC mRNA

NCBI chr14:65,638,931...65,662,908
Ensembl chr14:65,638,122...65,662,921

G

podocan

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PODN mRNA

NCBI chr 4:107,871,990...107,889,544
Ensembl chr 4:107,871,988...107,889,534

G

popeye domain containing 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of POPDC3 mRNA

NCBI chr10:45,165,401...45,194,546
Ensembl chr10:45,054,194...45,194,548

G

periostin, osteoblast specific factor

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of POSTN mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of and results in increased methylation of POSTN mRNA

PMID:36314267 PMID:36695872

NCBI chr 3:54,266,688...54,298,462
Ensembl chr 3:54,268,530...54,298,458

G

protection of telomeres 1A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of POT1A protein

NCBI chr 6:25,743,939...25,809,280
Ensembl chr 6:25,743,736...25,809,245

G

protection of telomeres 1B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of POT1B protein

NCBI chr17:55,958,190...56,019,647
Ensembl chr17:55,958,951...56,019,628

G

POU domain, class 3, transcription factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of POU3F1 mRNA

NCBI chr 4:124,551,439...124,554,448
Ensembl chr 4:124,550,600...124,554,448

G

POU domain, class 4, transcription factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of POU4F1 mRNA

NCBI chr14:104,699,111...104,705,554
Ensembl chr14:104,699,112...104,705,435

G

POU domain, class 5, transcription factor 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of POU5F1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of POU5F1 protein

PMID:30476341 PMID:37364752

NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669

G

peroxisome proliferator activated receptor alpha

multiple interactions
increases activity
increases expression
affects binding
decreases expression

mono-(2-ethylhexyl)phthalate binds to and results in increased activity of PPARA protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [PPARA protein binds to NCOR1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to EP300 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to MED1 protein]; mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to PPARGC1A protein]
mono-(2-ethylhexyl)phthalate results in increased activity of PPARA protein
mono-(2-ethylhexyl)phthalate results in increased expression of PPARA mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PPARA protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of PPARA mRNA; mono-(2-ethylhexyl)phthalate inhibits the reaction [PPARA protein binds to NCOR1 protein]; PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]; PPARA inhibits the reaction [PPARA gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FGF21 mRNA]]
mono-(2-ethylhexyl)phthalate binds to PPARA protein
mono-(2-ethylhexyl)phthalate results in decreased expression of PPARA protein

PMID:10581215 PMID:15647598 PMID:16326050 PMID:20123618 PMID:27551952 More...

NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020

G

peroxisome proliferator activator receptor delta

affects binding
increases activity
affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate binds to PPARB protein
mono-(2-ethylhexyl)phthalate results in increased activity of PPARD protein
mono-(2-ethylhexyl)phthalate affects the expression of PPARD mRNA; mono-(2-ethylhexyl)phthalate affects the expression of PPARD protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARD mRNA

PMID:15647598 PMID:23843199 PMID:27551952 PMID:31884101

NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448

G

peroxisome proliferator activated receptor gamma

multiple interactions
increases expression
decreases expression
affects binding
increases activity
affects activity
affects expression

2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]; [Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in decreased methylation of PPARG promoter; mono-(2-ethylhexyl)phthalate binds to and affects the folding of and results in increased activity of PPARG protein; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of PPARG protein; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of MMP9 protein]; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]; PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]; Rosiglitazone promotes the reaction [PPARG protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CASP3 protein]]
mono-(2-ethylhexyl)phthalate results in increased expression of PPARG mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PPARG protein
mono-(2-ethylhexyl)phthalate results in decreased expression of PPARG mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of PPARG protein
mono-(2-ethylhexyl)phthalate binds to PPARG protein
mono-(2-ethylhexyl)phthalate analog results in increased activity of PPARG protein; mono-(2-ethylhexyl)phthalate results in increased activity of PPARG protein
mono-(2-ethylhexyl)phthalate affects the activity of PPARG protein
mono-(2-ethylhexyl)phthalate affects the expression of PPARG mRNA
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of PPARG mRNA; mono-(2-ethylhexyl)phthalate binds to and results in increased activity of PPARG protein

PMID:10581215 PMID:12927354 PMID:15322177 PMID:15647598 PMID:16326050 More...

NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360

G

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate promotes the reaction [PPARA protein binds to PPARGC1A protein]
mono-(2-ethylhexyl)phthalate results in increased expression of PPARGC1A mRNA

PMID:20123618 PMID:25543134 PMID:32522588

NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068

G

peroxisome proliferative activated receptor, gamma, coactivator 1 beta

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of PPARGC1B mRNA

NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502

G

protein phosphatase, EF hand calcium-binding domain 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PPEF2 mRNA

NCBI chr 5:92,374,109...92,404,759
Ensembl chr 5:92,374,538...92,404,137

G

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PPFIA3 mRNA

NCBI chr 7:44,988,550...45,016,443
Ensembl chr 7:44,988,546...45,016,443

G

PTPRF interacting protein, binding protein 2 (liprin beta 2)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PPFIBP2 mRNA

NCBI chr 7:107,192,608...107,347,790
Ensembl chr 7:107,194,414...107,347,790

G

protein phosphatase 1, regulatory subunit 15A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PPP1R15A mRNA

NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692

G

protein phosphatase 1, regulatory subunit 18

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of PPP1R18 mRNA

NCBI chr17:36,176,483...36,186,488
Ensembl chr17:36,176,485...36,186,488

G

protein phosphatase 1, regulatory inhibitor subunit 1A

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of PPP1R1A mRNA

NCBI chr15:103,438,706...103,446,465
Ensembl chr15:103,438,706...103,446,430

G

protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of and results in increased activity of PPP2CA protein; Zinc inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of PPP2CA protein]

NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605

G

protein phosphatase 2, regulatory subunit B, beta

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PPP2R2B mRNA

NCBI chr18:42,777,811...43,192,827
Ensembl chr18:42,770,497...43,216,192

G

PRAME like 13

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PRAMEF12 mRNA

NCBI chr 4:144,118,244...144,135,037
Ensembl chr 4:144,118,244...144,135,034

G

PRAME like 3E

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PRAMEL3E mRNA

NCBI chr X:134,395,314...134,405,504
Ensembl chr X:134,395,337...134,405,343

G

photoreceptor disc component

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PRCD mRNA

NCBI chr11:116,544,603...116,559,224
Ensembl chr11:116,544,360...116,559,215

G

PR domain containing 14

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRDM14 protein

NCBI chr 1:13,183,649...13,197,467
Ensembl chr 1:13,183,681...13,197,387

G

PR domain containing 16

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRDM16 mRNA

NCBI chr 4:154,400,579...154,721,851
Ensembl chr 4:154,400,582...154,721,330

G

peroxiredoxin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRDX2 mRNA

NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463

G

protein kinase, AMP-activated, beta 2 non-catalytic subunit

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PRKAB2 mRNA

NCBI chr 3:97,565,527...97,581,128
Ensembl chr 3:97,565,509...97,581,128

G

protein kinase, cAMP dependent, catalytic, alpha

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PRKACA mRNA
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PRKACA mRNA]

PMID:25543134 PMID:36889213

NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072

G

protein kinase, AMP-activated, gamma 2 non-catalytic subunit

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRKAG2 mRNA

NCBI chr 5:25,067,733...25,311,576
Ensembl chr 5:25,067,742...25,305,640

G

protein kinase, AMP-activated, gamma 3 non-catalytic subunit

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PRKAG3 mRNA

NCBI chr 1:74,778,062...74,788,623
Ensembl chr 1:74,778,081...74,788,380

G

protein kinase C, alpha

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRKCA mRNA

NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754

G

protein kinase, cGMP-dependent, type I

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PRKG1 mRNA

NCBI chr19:30,541,887...31,742,675
Ensembl chr19:30,541,889...31,742,433

G

prolactin receptor

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRLR mRNA

NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266

G

prion protein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PRNP mRNA

NCBI chr 2:131,751,848...131,780,356
Ensembl chr 2:131,751,848...131,780,349

G

peripherin

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PRPH mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PRPH mRNA

PMID:22401849 PMID:36189433

NCBI chr15:98,951,452...98,956,858
Ensembl chr15:98,953,055...98,956,859

G

proline rich 15-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PRR15L mRNA

NCBI chr11:96,816,987...96,826,474
Ensembl chr11:96,818,930...96,828,656

G

proline rich 23A, member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PRR23A3 mRNA

NCBI chr 9:98,746,820...98,748,633
Ensembl chr 9:98,746,820...98,748,636

G

proline-rich transmembrane protein 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PRRT3 mRNA

NCBI chr 6:113,470,599...113,479,071
Ensembl chr 6:113,470,600...113,478,892

G

serine protease 12 neurotrypsin (motopsin)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PRSS12 mRNA

NCBI chr 3:123,240,562...123,300,251
Ensembl chr 3:123,240,562...123,300,246

G

protogenin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PRTG mRNA

NCBI chr 9:72,714,556...72,824,589
Ensembl chr 9:72,714,156...72,824,573

G

phosphoserine aminotransferase 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of PSAT1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PSAT1 mRNA

PMID:36189433 PMID:36695872

NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701

G

pregnancy-specific beta-1-glycoprotein 22

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PSG22 mRNA

NCBI chr 7:18,451,976...18,461,363
Ensembl chr 7:18,452,015...18,461,173

G

platelet-activating factor receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PTAFR mRNA

NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994

G

patched 1

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Androgens deficiency] results in increased expression of PTCH1 mRNA; mono-(2-ethylhexyl)phthalate inhibits the reaction [cyclopamine results in decreased expression of PTCH1 mRNA]
mono-(2-ethylhexyl)phthalate results in increased expression of PTCH1 mRNA

NCBI chr13:63,656,142...63,721,274
Ensembl chr13:63,656,142...63,721,412

G

patched domain containing 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PTCHD3 mRNA

NCBI chr11:121,721,050...121,734,259
Ensembl chr11:121,721,073...121,734,249

G

patched domain containing 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PTCHD4 mRNA

NCBI chr17:42,626,646...43,004,339
Ensembl chr17:42,626,838...42,815,968

G

phosphatase and tensin homolog

multiple interactions

[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN mRNA; [bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN protein; [mono-(2-ethylhexyl)phthalate co-treated with bisphenol A co-treated with tubastatin A] results in increased expression of PTEN mRNA; [mono-(2-ethylhexyl)phthalate co-treated with tubastatin A] results in increased expression of PTEN mRNA; HDAC6 protein affects the reaction [[bisphenol A co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of PTEN protein]

NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560

G

prostaglandin D2 synthase (brain)

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PTGDS mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of PTGDS mRNA

NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058

G

prostaglandin E receptor 2 (subtype EP2)

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PTGER2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER2 mRNA
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER2 mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER2 protein]

PMID:36189433 PMID:36889213

NCBI chr14:45,225,568...45,241,277
Ensembl chr14:45,225,652...45,241,277

G

prostaglandin E receptor 4 (subtype EP4)

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER4 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER4 protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PTGER4 mRNA
PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER4 mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER4 protein]

PMID:36189433 PMID:36889213

NCBI chr15:5,262,880...5,273,668
Ensembl chr15:5,236,142...5,273,668

G

prostaglandin E synthase

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Genistein] affects the expression of PTGES mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of PTGES mRNA

PMID:34942354 PMID:36695872

NCBI chr 2:30,779,483...30,793,309
Ensembl chr 2:30,779,483...30,819,875

G

prostaglandin-endoperoxide synthase 1

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in decreased expression of PTGS1 mRNA; [mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in decreased expression of PTGS1 protein
mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS1 protein

NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284

G

prostaglandin-endoperoxide synthase 2

multiple interactions
increases expression
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of PTGS2 protein; Dexamethasone inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PTGS2 mRNA]
mono-(2-ethylhexyl)phthalate results in increased expression of PTGS2 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of PTGS2 protein
mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of PTGS2 protein
[PTGS2 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of GNAS protein; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of HAS2 mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PRKACA mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER2 mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER2 protein]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER4 mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of PTGER4 protein]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BAX mRNA]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP3 protein]; PTGS2 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP7 protein]

PMID:9013627 PMID:23360888 PMID:29089286 PMID:34942354 PMID:36889213

NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978

G

parathyroid hormone 2 receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PTH2R mRNA

NCBI chr 1:65,317,921...65,428,784
Ensembl chr 1:65,321,215...65,428,403

G

PTK2 protein tyrosine kinase 2 beta

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PTK2B mRNA

NCBI chr14:66,390,706...66,518,549
Ensembl chr14:66,390,706...66,518,501

G

protein tyrosine phosphatase 4a3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PTP4A3 mRNA

NCBI chr15:73,594,991...73,629,075
Ensembl chr15:73,594,994...73,630,615

G

protein tyrosine phosphatase, non-receptor type 13

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of PTPN13 mRNA

NCBI chr 5:103,573,058...103,746,227
Ensembl chr 5:103,573,058...103,746,169

G

protein tyrosine phosphatase, non-receptor type 18

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PTPN18 mRNA

NCBI chr 1:34,498,827...34,514,811
Ensembl chr 1:34,498,843...34,514,814

G

protein tyrosine phosphatase receptor type D

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PTPRD mRNA

NCBI chr 4:75,859,474...78,132,282
Ensembl chr 4:75,859,475...78,130,198

G

protein tyrosine phosphatase receptor type H

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PTPRH mRNA

NCBI chr 7:4,551,607...4,607,040
Ensembl chr 7:4,551,611...4,607,040

G

protein tyrosine phosphatase receptor type O

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PTPRO mRNA

NCBI chr 6:137,229,189...137,440,251
Ensembl chr 6:137,229,317...137,440,231

G

protein tyrosine phosphatase receptor type Q

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of PTPRQ mRNA

NCBI chr10:107,350,224...107,555,939
Ensembl chr10:107,352,910...107,555,912

G

protein tyrosine phosphatase receptor type V

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of PTPRV mRNA

NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332

G

pentraxin related gene

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PTX3 mRNA

NCBI chr 3:66,127,308...66,133,227
Ensembl chr 3:66,127,331...66,133,226

G

PYD and CARD domain containing

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of PYCARD protein

NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039

G

glutamine rich 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of QRICH2 mRNA

NCBI chr11:116,332,149...116,357,092
Ensembl chr11:116,332,151...116,357,067

G

RAB13, member RAS oncogene family

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB13 protein

NCBI chr 3:90,121,022...90,133,694
Ensembl chr 3:90,121,002...90,133,692

G

RAB20, member RAS oncogene family

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RAB20 mRNA

NCBI chr 8:11,503,390...11,528,640
Ensembl chr 8:11,503,518...11,528,710

G

RAB27A, member RAS oncogene family

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RAB27A mRNA

NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911

G

RAB8A, member RAS oncogene family

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of RAB8A protein

NCBI chr 8:72,915,044...72,935,210
Ensembl chr 8:72,915,044...72,937,748

G

Rab geranylgeranyl transferase, a subunit

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RABGGTA mRNA

NCBI chr14:55,953,321...55,959,720
Ensembl chr14:55,952,873...55,959,720

G

RAN binding protein 17

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RANBP17 mRNA

NCBI chr11:33,161,794...33,463,789
Ensembl chr11:33,161,795...33,463,746

G

retinoic acid receptor, beta

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RARB mRNA

NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924

G

RAS protein activator like 1 (GAP1 like)

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RASAL1 mRNA

NCBI chr 5:120,786,105...120,817,662
Ensembl chr 5:120,786,877...120,817,662

G

RAS, dexamethasone-induced 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RASD1 mRNA

NCBI chr11:59,854,007...59,855,770
Ensembl chr11:59,854,007...59,855,770

G

RASD family, member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RASD2 mRNA

NCBI chr 8:75,940,572...75,950,741
Ensembl chr 8:75,940,572...75,950,741

G

RasGEF domain family, member 1C

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of RASGEF1C mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RASGEF1C mRNA

PMID:22401849 PMID:36189433

NCBI chr11:49,791,996...49,871,050
Ensembl chr11:49,792,662...49,871,821

G

RAS protein-specific guanine nucleotide-releasing factor 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RASGRF2 mRNA

PMID:22401849 PMID:36695872

NCBI chr13:92,028,526...92,268,584
Ensembl chr13:92,028,519...92,268,164

G

Ras association (RalGDS/AF-6) domain family (N-terminal) member 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RASSF10 mRNA

NCBI chr 7:112,553,169...112,556,665
Ensembl chr 7:112,553,169...112,556,664

G

Ras association (RalGDS/AF-6) domain family member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RASSF4 mRNA

NCBI chr 6:116,609,969...116,650,797
Ensembl chr 6:116,609,969...116,650,913

G

retinoblastoma binding protein 7, chromatin remodeling factor

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of RBBP7 mRNA

NCBI chr X:161,543,368...161,562,086
Ensembl chr X:161,543,398...161,562,088

G

ribokinase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RBKS mRNA

NCBI chr 5:31,781,783...31,855,042
Ensembl chr 5:31,781,783...31,854,971

G

RNA binding motif protein 24

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RBM24 mRNA

NCBI chr13:46,571,664...46,584,575
Ensembl chr13:46,571,910...46,584,571

G

RNA binding motif (RNP1, RRM) protein 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RBM3 mRNA

NCBI chr X:8,005,214...8,012,119
Ensembl chr X:8,005,214...8,012,119

G

RNA binding motif protein 44

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of RBM44 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RBM44 mRNA

PMID:22401849 PMID:36189433

NCBI chr 1:91,072,695...91,098,521
Ensembl chr 1:91,072,811...91,098,517

G

RNA binding motif protein, X chromosome

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of RBMX mRNA

NCBI chr X:56,428,708...56,438,405
Ensembl chr X:56,428,890...56,438,396

G

retinol binding protein 1, cellular

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of RBP1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RBP1 mRNA

PMID:30476341 PMID:36189433

NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628

G

retinol binding protein 4, plasma

multiple interactions
increases expression

RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [[mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of IRS1 protein]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of PIK3R1 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of RBP4 protein

NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729

G

recombination signal binding protein for immunoglobulin kappa J region-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RBPJL mRNA

NCBI chr 2:164,244,996...164,257,368
Ensembl chr 2:164,245,061...164,257,368

G

retinol dehydrogenase 1 (all trans)

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RDH1 mRNA

NCBI chr10:127,595,595...127,604,168
Ensembl chr10:127,595,590...127,604,166

G

REC8 meiotic recombination protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of REC8 mRNA

NCBI chr14:55,855,459...55,862,852
Ensembl chr14:55,855,494...55,862,852

G

RecQ protein-like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RECQL mRNA

NCBI chr 6:142,296,068...142,332,802
Ensembl chr 6:142,296,068...142,332,813

G

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

increases expression
multiple interactions
affects expression

mono-(2-ethylhexyl)phthalate results in increased expression of RELA mRNA
fulvestrant inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of RELA protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased activity of RELA protein; mono-(2-ethylhexyl)phthalate results in increased phosphorylation of and affects the localization of RELA protein
mono-(2-ethylhexyl)phthalate results in increased expression of RELA protein modified form
mono-(2-ethylhexyl)phthalate affects the expression of RELA protein

PMID:28390675 PMID:31016965 PMID:38048874

NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158

G

rad and gem related GTP binding protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of REM2 mRNA

NCBI chr14:54,713,676...54,717,889
Ensembl chr14:54,713,557...54,717,888

G

regulator of cell cycle

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RGCC mRNA

NCBI chr14:79,526,190...79,539,075
Ensembl chr14:79,526,196...79,539,085

G

regulator of G-protein signaling 16

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RGS16 mRNA

NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214

G

regulator of G-protein signaling 4

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RGS4 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of RGS4 mRNA

PMID:36314267 PMID:36695872

NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211

G

regulator of G-protein signaling 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RGS6 mRNA

NCBI chr12:82,663,325...83,208,835
Ensembl chr12:82,635,066...83,208,830

G

regulator of G protein signaling 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RGS7 mRNA

NCBI chr 1:174,886,642...175,320,287
Ensembl chr 1:174,886,653...175,320,066

G

ras homolog family member D

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RHOD mRNA

NCBI chr19:4,473,500...4,489,562
Ensembl chr19:4,475,487...4,489,460

G

reproductive homeobox 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RHOX10 mRNA

NCBI chr X:37,155,352...37,160,565
Ensembl chr X:37,155,352...37,160,568

G

reproductive homeobox 13

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RHOX13 mRNA

NCBI chr X:37,210,059...37,218,850
Ensembl chr X:37,210,096...37,218,844

G

reproductive homeobox 2A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RHOX2A mRNA

NCBI chr X:36,508,645...36,513,343
Ensembl chr X:36,508,629...36,513,339

G

reproductive homeobox 8

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of RHOX8 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RHOX8 mRNA

NCBI chr X:36,963,657...36,979,643
Ensembl chr X:36,963,655...36,967,821

G

reproductive homeobox 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RHOX9 mRNA

NCBI chr X:36,987,974...36,990,647
Ensembl chr X:36,987,974...36,990,647

G

RIMS binding protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RIMBP2 mRNA

NCBI chr 5:128,834,852...129,030,636
Ensembl chr 5:128,834,855...129,030,550

G

regulating synaptic membrane exocytosis 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RIMS1 mRNA

NCBI chr 1:22,356,196...22,845,239
Ensembl chr 1:22,356,475...22,845,203

G

regulating synaptic membrane exocytosis 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RIMS4 mRNA

NCBI chr 2:163,701,676...163,760,893
Ensembl chr 2:163,701,671...163,760,603

G

Ras and Rab interactor 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RIN3 mRNA

NCBI chr12:102,248,572...102,358,982
Ensembl chr12:102,249,307...102,357,114

G

RIPOR family member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RIPOR3 mRNA

NCBI chr 2:167,822,081...167,892,809
Ensembl chr 2:167,822,084...167,852,538

G

Rho family GTPase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RND1 mRNA

NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342

G

Rho family GTPase 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of RND3 mRNA

NCBI chr 2:51,020,451...51,039,123
Ensembl chr 2:51,020,450...51,039,123

G

ring finger protein 112

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RNF112 mRNA

NCBI chr11:61,339,243...61,345,014
Ensembl chr11:61,339,268...61,344,957

G

ring finger protein 123

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RNF123 mRNA

NCBI chr 9:107,928,869...107,957,183
Ensembl chr 9:107,928,733...107,960,545

G

ring finger protein 152

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RNF152 mRNA

NCBI chr 1:105,204,642...105,284,665
Ensembl chr 1:105,204,639...105,284,435

G

ring finger protein 180

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RNF180 mRNA

NCBI chr13:105,267,075...105,431,406
Ensembl chr13:105,266,509...105,431,323

G

ring finger protein 207

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RNF207 mRNA

NCBI chr 4:152,391,475...152,403,686
Ensembl chr 4:152,391,476...152,403,450

G

ring finger protein 222

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of RNF222 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RNF222 mRNA

NCBI chr11:68,772,947...68,786,605
Ensembl chr11:68,779,379...68,786,603

G

roundabout guidance receptor 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ROBO2 mRNA

NCBI chr16:73,688,725...75,244,331
Ensembl chr16:73,688,727...74,208,713

G

RAR-related orphan receptor alpha

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RORA mRNA

NCBI chr 9:68,560,627...69,295,528
Ensembl chr 9:68,561,068...69,295,528

G

RAR-related orphan receptor beta

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RORB mRNA

NCBI chr19:18,907,966...19,088,560
Ensembl chr19:18,907,969...19,088,560

G

rabphilin 3A

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of RPH3A mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RPH3A mRNA

PMID:22401849 PMID:36189433

NCBI chr 5:121,078,562...121,184,249
Ensembl chr 5:121,078,562...121,148,155

G

ribosomal protein L23

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of RPL23 mRNA

NCBI chr11:97,668,352...97,673,265
Ensembl chr11:97,668,353...97,673,263

G

ribosomal protein L3-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RPL3L mRNA

NCBI chr17:24,946,800...24,955,117
Ensembl chr17:24,946,794...24,955,117

G

ribonuclease P/MRP 25 subunit

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RPP25 mRNA

NCBI chr 9:57,411,385...57,412,730
Ensembl chr 9:57,411,309...57,412,731

G

reprimo-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RPRML mRNA

NCBI chr11:103,540,335...103,541,406
Ensembl chr11:103,540,396...103,541,405

G

ribosomal protein S6

multiple interactions
increases phosphorylation

epigallocatechin gallate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of RPS6 protein]

NCBI chr 4:86,772,336...86,775,604
Ensembl chr 4:86,772,897...86,775,649

G

Ras-related associated with diabetes

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of RRAD mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RRAD mRNA

PMID:22401849 PMID:36189433

NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959

G

Ras-related GTP binding D

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RRAGD mRNA

NCBI chr 4:32,982,998...33,022,180
Ensembl chr 4:32,983,037...33,022,180

G

radial spoke head 1 homolog (Chlamydomonas)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RSPH1 mRNA

NCBI chr17:31,473,993...31,496,270
Ensembl chr17:31,473,993...31,496,357

G

radial spoke head 4 homolog A (Chlamydomonas)

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of RSPH4A mRNA

NCBI chr10:33,781,107...33,792,017
Ensembl chr10:33,781,107...33,792,017

G

radial spoke head 9 homolog (Chlamydomonas)

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of RSPH9 mRNA

NCBI chr17:46,432,964...46,455,171
Ensembl chr17:46,432,961...46,455,142

G

retrotransposon Gag like 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RTL3 mRNA

NCBI chr X:105,880,688...105,884,145
Ensembl chr X:105,880,688...105,884,250

G

reticulon 4 receptor

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of RTN4R mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RTN4R mRNA

NCBI chr16:17,945,506...17,970,272
Ensembl chr16:17,945,506...17,970,272

G

RUN and FYVE domain containing 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of RUFY4 mRNA

NCBI chr 1:74,163,768...74,187,389
Ensembl chr 1:74,164,700...74,187,382

G

runt related transcription factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of RUNX1 mRNA

NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037

G

runt related transcription factor 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RUNX2 mRNA

PMID:22401849 PMID:25777084

NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684

G

retinoid X receptor alpha

affects binding

mono-(2-ethylhexyl)phthalate binds to RXRA protein

NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969

G

retinoid X receptor beta

affects binding

mono-(2-ethylhexyl)phthalate binds to RXRB protein

NCBI chr17:34,250,786...34,257,377
Ensembl chr17:34,250,786...34,257,373

G

retinoid X receptor gamma

affects binding

mono-(2-ethylhexyl)phthalate binds to RXRG protein

NCBI chr 1:167,425,902...167,467,191
Ensembl chr 1:167,425,953...167,467,192

G

ryanodine receptor 1, skeletal muscle

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of RYR1 mRNA

NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604

G

sterile alpha motif domain containing 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SAMD5 mRNA

NCBI chr10:9,138,205...9,551,670
Ensembl chr10:9,498,680...9,550,952

G

special AT-rich sequence binding protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SATB2 mRNA

NCBI chr 1:56,833,145...57,019,350
Ensembl chr 1:56,833,140...57,017,809

G

SH3 domain binding kinase family, member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SBK3 mRNA

NCBI chr 7:4,968,246...4,995,756
Ensembl chr 7:4,968,259...4,974,167

G

scavenger receptor class A, member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SCARA3 mRNA

NCBI chr14:66,156,844...66,191,427
Ensembl chr14:66,156,843...66,191,384

G

scavenger receptor class B, member 1

decreases expression
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 protein
mono-(2-ethylhexyl)phthalate results in increased expression of SCARB1 mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of SCARB1 mRNA; METTL14 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of SCARB1 mRNA]; mono-(2-ethylhexyl)phthalate affects the reaction [METTL14 protein affects the expression of SCARB1 mRNA]; mono-(2-ethylhexyl)phthalate results in decreased expression of and results in decreased methylation of SCARB1 mRNA

PMID:22087261 PMID:22401849 PMID:27181934 PMID:31875672

NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158

G

stearoyl-Coenzyme A desaturase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SCD mRNA

NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303

G

secretogranin III

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SCG3 mRNA

NCBI chr 9:75,550,648...75,591,733
Ensembl chr 9:75,550,471...75,591,338

G

secretoglobin, family 2B, member 22, pseudogene

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SCGB2B22-PS mRNA

Ensembl chr 7:33,303,689...33,305,477

G

scinderin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SCIN mRNA

NCBI chr12:40,109,768...40,184,227
Ensembl chr12:40,109,768...40,184,227

G

sodium channel, voltage-gated, type X, alpha

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SCN10A mRNA

NCBI chr 9:119,437,522...119,548,388
Ensembl chr 9:119,437,522...119,548,388

G

sodium channel, voltage-gated, type I, alpha

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SCN1A mRNA

NCBI chr 2:66,101,125...66,271,181
Ensembl chr 2:66,101,122...66,271,184

G

sodium channel, voltage-gated, type III, beta

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SCN3B mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SCN3B mRNA

NCBI chr 9:40,180,512...40,202,914
Ensembl chr 9:40,180,513...40,202,914

G

sodium channel, voltage-gated, type IX, alpha

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SCN9A mRNA

NCBI chr 2:66,310,424...66,465,456
Ensembl chr 2:66,310,424...66,465,306

G

secretin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SCT mRNA

NCBI chr 7:140,858,243...140,859,082
Ensembl chr 7:140,858,243...140,859,046

G

signal peptide, CUB domain, EGF-like 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SCUBE2 mRNA

NCBI chr 7:109,397,897...109,464,886
Ensembl chr 7:109,397,883...109,464,886

G

SEC14-like lipid binding 4

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of SEC14L4 mRNA

NCBI chr11:3,981,377...3,998,426
Ensembl chr11:3,981,462...3,998,024

G

SEC62 homolog, preprotein translocation

decreases methylation

mono-(2-ethylhexyl)phthalate results in decreased methylation of SEC62 mRNA

NCBI chr 3:30,847,025...30,875,412
Ensembl chr 3:30,847,024...30,875,412

G

sel-1 suppressor of lin-12-like 3 (C. elegans)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SEL1L3 mRNA

NCBI chr 5:53,264,425...53,370,794
Ensembl chr 5:53,264,425...53,371,269

G

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SEMA3D mRNA

NCBI chr 5:12,433,133...12,638,920
Ensembl chr 5:12,433,352...12,638,915

G

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SEMA3G mRNA

NCBI chr14:30,939,830...30,952,309
Ensembl chr14:30,939,817...30,952,309

G

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SEMA4G mRNA

NCBI chr19:44,976,838...44,991,836
Ensembl chr19:44,977,540...44,991,836

G

septin 12

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SEPT12 mRNA

NCBI chr16:4,804,722...4,815,716
Ensembl chr16:4,804,722...4,815,716

G

serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERPINA12 mRNA

NCBI chr12:103,995,028...104,010,702
Ensembl chr12:103,995,028...104,010,702

G

serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERPINA16 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SERPINA16 mRNA

NCBI chr12:103,635,067...103,643,100
Ensembl chr12:103,635,067...103,642,398

G

serine (or cysteine) peptidase inhibitor, clade A, member 3A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERPINA3A mRNA

NCBI chr12:104,078,983...104,088,155
Ensembl chr12:104,078,983...104,088,155

G

serine (or cysteine) peptidase inhibitor, clade A, member 3N

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SERPINA3N mRNA

NCBI chr12:104,372,967...104,380,588
Ensembl chr12:104,372,988...104,380,588

G

serine (or cysteine) peptidase inhibitor, clade A, member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERPINA5 mRNA

NCBI chr12:104,065,572...104,072,397
Ensembl chr12:104,067,372...104,072,396

G

serine (or cysteine) peptidase inhibitor, clade B, member 1a

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SERPINB1A mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERPINB1A mRNA

PMID:36189433 PMID:38113427

NCBI chr13:33,026,075...33,037,189
Ensembl chr13:33,026,075...33,035,168

G

serine (or cysteine) peptidase inhibitor, clade B, member 1b

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERPINB1B mRNA

NCBI chr13:33,262,478...33,278,363
Ensembl chr13:33,262,558...33,278,363

G

serine (or cysteine) peptidase inhibitor, clade E, member 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SERPINE1 mRNA

NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122

G

serine rich and transmembrane domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SERTM1 mRNA

NCBI chr 3:54,804,489...54,823,308
Ensembl chr 3:54,804,489...54,823,308

G

serine rich and transmembrane domain containing 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SERTM2 mRNA

NCBI chr X:142,936,691...142,949,270
Ensembl chr X:142,936,691...142,949,270

G

sestrin 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SESN2 mRNA

NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812

G

seizure related gene 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SEZ6 mRNA

NCBI chr11:77,821,403...77,869,874
Ensembl chr11:77,821,626...77,869,874

G

stratifin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SFN mRNA

NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479

G

secreted frizzled-related protein 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SFRP4 mRNA

NCBI chr13:19,807,345...19,816,995
Ensembl chr13:19,807,274...19,817,164

G

surfactant associated protein C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SFTPC mRNA

NCBI chr14:70,758,381...70,761,521
Ensembl chr14:70,758,389...70,761,521

G

sarcoglycan, delta (dystrophin-associated glycoprotein)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SGCD mRNA

NCBI chr11:46,861,904...47,880,309
Ensembl chr11:46,787,080...47,879,796

G

sarcoglycan, gamma (dystrophin-associated glycoprotein)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SGCG mRNA

NCBI chr14:61,456,555...61,495,939
Ensembl chr14:61,456,564...61,495,939

G

serum/glucocorticoid regulated kinase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SGK1 mRNA

NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802

G

sphingosine-1-phosphate phosphatase 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SGPP2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SGPP2 mRNA

NCBI chr 1:78,286,186...78,396,926
Ensembl chr 1:78,286,982...78,396,926

G

small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SGTB mRNA

NCBI chr13:104,246,233...104,278,369
Ensembl chr13:104,246,249...104,278,243

G

SH2 domain containing 2A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SH2D2A mRNA

NCBI chr 3:87,754,070...87,763,116
Ensembl chr 3:87,754,062...87,763,029

G

SH3-binding domain glutamic acid-rich protein

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SH3BGR mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SH3BGR mRNA

PMID:22401849 PMID:36189433

NCBI chr16:96,001,670...96,030,133
Ensembl chr16:96,001,650...96,030,135

G

SH3-domain binding protein 5 (BTK-associated)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SH3BP5 mRNA

NCBI chr14:31,094,571...31,158,056
Ensembl chr14:31,081,837...31,158,035

G

SH3 domain containing ring finger 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SH3RF1 mRNA

NCBI chr 8:61,677,117...61,918,327
Ensembl chr 8:61,676,906...61,849,105

G

SH3 domain containing ring finger 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SH3RF2 mRNA

NCBI chr18:42,185,531...42,291,760
Ensembl chr18:42,186,732...42,292,025

G

sex hormone binding globulin

decreases secretion
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in decreased secretion of SHBG protein
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SHBG mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of SHBG mRNA

PMID:24945889 PMID:36189433

NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731

G

src homology 2 domain-containing transforming protein C3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SHC3 mRNA

NCBI chr13:51,577,422...51,724,909
Ensembl chr13:51,585,077...51,723,523

G

SHC (Src homology 2 domain containing) family, member 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SHC4 mRNA

NCBI chr 2:125,469,359...125,566,085
Ensembl chr 2:125,469,367...125,566,068

G

sonic hedgehog

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SHH mRNA

NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254

G

shisa family member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SHISA3 mRNA

NCBI chr 5:67,765,226...67,771,330
Ensembl chr 5:67,765,225...67,780,895

G

shisa family member 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SHISA6 mRNA

NCBI chr11:66,102,551...66,418,715
Ensembl chr11:66,102,551...66,416,790

G

shisa family member 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SHISA9 mRNA

NCBI chr16:11,801,457...12,088,768
Ensembl chr16:11,801,977...12,088,766

G

Sh3kbp1 binding protein 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SHKBP1 mRNA

NCBI chr 7:27,041,553...27,055,440
Ensembl chr 7:27,041,558...27,055,444

G

SID1 transmembrane family, member 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SIDT1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SIDT1 mRNA

NCBI chr16:44,060,540...44,153,575
Ensembl chr16:44,060,543...44,153,559

G

signal-regulatory protein beta 1A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRPB1 mRNA

NCBI chr 3:15,436,887...15,491,487
Ensembl chr 3:15,436,713...15,491,580

G

sirtuin 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT1 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT1 protein

NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483

G

sirtuin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT2 protein

NCBI chr 7:28,466,192...28,488,086
Ensembl chr 7:28,466,160...28,488,086

G

sirtuin 3

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SIRT3 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 protein

PMID:25543134 PMID:31016965 PMID:32522588

NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222

G

sirtuin 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT4 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT4 protein

NCBI chr 5:115,616,065...115,628,322
Ensembl chr 5:115,616,069...115,622,784

G

sirtuin 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT5 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT5 protein

NCBI chr13:43,518,849...43,549,073
Ensembl chr13:43,518,972...43,548,679

G

sirtuin 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT6 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT6 protein

NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631

G

sirtuin 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT7 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT7 protein

NCBI chr11:120,509,197...120,515,840
Ensembl chr11:120,509,198...120,516,066

G

sucrase isomaltase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SIS mRNA

NCBI chr 3:72,795,890...72,875,196
Ensembl chr 3:72,795,890...72,875,196

G

sine oculis-related homeobox 2

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of SIX2 mRNA

NCBI chr17:85,970,276...85,995,682
Ensembl chr17:85,991,705...85,995,702

G

SKI/DACH domain containing 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SKIDA1 mRNA

NCBI chr 2:18,048,510...18,053,627
Ensembl chr 2:18,045,487...18,053,862

G

SKI family transcriptional corepressor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SKOR1 mRNA

NCBI chr 9:63,045,446...63,056,243
Ensembl chr 9:63,045,452...63,056,243

G

S-phase kinase-associated protein 2

multiple interactions

[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in decreased expression of SKP2 mRNA

NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512

G

solute carrier family 10 (sodium/bile acid cotransporter family), member 7

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC10A7 mRNA

NCBI chr 8:79,235,957...79,460,641
Ensembl chr 8:79,235,975...79,460,632

G

solute carrier family 12, member 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC12A1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC12A1 mRNA

NCBI chr 2:124,994,430...125,071,922
Ensembl chr 2:124,994,425...125,071,922

G

solute carrier family 12 (potassium/chloride transporters), member 8

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC12A8 mRNA

NCBI chr16:33,337,440...33,484,508
Ensembl chr16:33,337,698...33,484,505

G

solute carrier family 13 (sodium/sulfate symporters), member 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC13A1 mRNA

NCBI chr 6:24,088,282...24,168,118
Ensembl chr 6:24,088,282...24,168,091

G

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC13A2 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SLC13A2 mRNA

NCBI chr11:78,288,102...78,313,107
Ensembl chr11:78,287,913...78,313,043

G

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2, opposite strand

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC13A2OS mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SLC13A2OS mRNA

NCBI chr11:78,285,311...78,296,483
Ensembl chr11:78,285,311...78,296,483

G

solute carrier family 16 (monocarboxylic acid transporters), member 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC16A10 mRNA

NCBI chr10:39,909,528...40,018,262
Ensembl chr10:39,909,528...40,018,254

G

solute carrier family 16 (monocarboxylic acid transporters), member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC16A5 mRNA

NCBI chr11:115,353,231...115,365,224
Ensembl chr11:115,353,300...115,365,224

G

solute carrier family 16 (monocarboxylic acid transporters), member 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC16A8 mRNA

NCBI chr15:79,135,216...79,139,619
Ensembl chr15:79,135,214...79,138,961

G

solute carrier family 17 (sodium phosphate), member 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC17A1 mRNA

NCBI chr13:24,051,607...24,079,713
Ensembl chr13:24,051,733...24,079,713

G

solute carrier family 1 (glial high affinity glutamate transporter), member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC1A3 mRNA

NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248

G

solute carrier family 22 (organic cation transporter), member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC22A4 mRNA

NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916

G

solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC25A20 mRNA

NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840

G

solute carrier family 25, member 30

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC25A30 mRNA

NCBI chr14:75,994,986...76,024,477
Ensembl chr14:75,997,557...76,024,477

G

solute carrier family 25, member 34

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SLC25A34 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC25A34 mRNA

NCBI chr 4:141,346,130...141,351,202
Ensembl chr 4:141,346,135...141,351,132

G

solute carrier family 25, member 38

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of SLC25A38 mRNA

NCBI chr 9:119,939,428...119,953,570
Ensembl chr 9:119,939,440...119,953,570

G

solute carrier family 25, member 41

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC25A41 mRNA

NCBI chr17:57,339,772...57,348,654
Ensembl chr17:57,339,773...57,348,654

G

solute carrier family 25, member 45

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC25A45 mRNA

NCBI chr19:5,927,828...5,935,796
Ensembl chr19:5,927,836...5,935,906

G

solute carrier family 25, member 48

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SLC25A48 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC25A48 mRNA

PMID:22401849 PMID:36189433

NCBI chr13:56,585,774...56,620,180
Ensembl chr13:56,586,168...56,622,052

G

solute carrier family 26, member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC26A3 mRNA

NCBI chr12:31,483,141...31,523,921
Ensembl chr12:31,440,870...31,523,916

G

solute carrier family 26, member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC26A5 mRNA

NCBI chr 5:22,013,999...22,070,602
Ensembl chr 5:22,015,653...22,070,602

G

solute carrier family 27 (fatty acid transporter), member 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC27A1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of SLC27A1 protein

NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946

G

solute carrier family 27 (fatty acid transporter), member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC27A2 mRNA

NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163

G

solute carrier family 2 (facilitated glucose transporter), member 1

increases expression
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC2A1 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SLC2A1 protein

PMID:31009676 PMID:38048874

NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180

G

solute carrier family 2 (facilitated glucose transporter), member 12

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC2A12 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC2A12 mRNA

PMID:36189433 PMID:36695872

NCBI chr10:22,488,821...22,579,779
Ensembl chr10:22,520,910...22,580,184

G

solute carrier family 2 (facilitated glucose transporter), member 4

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SLC2A4 mRNA
[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SLC2A4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of SLC2A4 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]

PMID:25543134 PMID:28526321

NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014

G

solute carrier family 32 (GABA vesicular transporter), member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC32A1 mRNA

NCBI chr 2:158,449,158...158,457,667
Ensembl chr 2:158,452,687...158,457,668

G

solute carrier family 34 (sodium phosphate), member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC34A2 mRNA

NCBI chr 5:53,206,695...53,229,006
Ensembl chr 5:53,195,423...53,229,006

G

solute carrier family 35, member D2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC35D2 mRNA

NCBI chr13:64,244,122...64,277,195
Ensembl chr13:64,244,122...64,277,182

G

solute carrier family 35, member F1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC35F1 mRNA

NCBI chr10:52,566,597...52,987,718
Ensembl chr10:52,566,629...52,987,718

G

solute carrier family 38, member 11

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC38A11 mRNA

NCBI chr 2:65,144,007...65,194,606
Ensembl chr 2:65,146,774...65,194,378

G

solute carrier family 44, member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC44A3 mRNA

NCBI chr 3:121,253,177...121,325,993
Ensembl chr 3:121,253,177...121,326,053

G

solute carrier family 45, member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC45A4 mRNA

NCBI chr15:73,449,267...73,517,606
Ensembl chr15:73,449,273...73,517,611

G

solute carrier family 4, sodium bicarbonate cotransporter-like, member 10

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC4A10 mRNA

NCBI chr 2:61,876,815...62,157,087
Ensembl chr 2:61,876,806...62,157,074

G

solute carrier protein family 52, member 3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SLC52A3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC52A3 mRNA

NCBI chr 2:151,838,431...151,851,178
Ensembl chr 2:151,838,431...151,851,178

G

solute carrier family 5 (sodium/glucose cotransporter), member 10

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC5A10 mRNA

NCBI chr11:61,563,608...61,611,641
Ensembl chr11:61,563,607...61,611,652

G

solute carrier family 5 (sodium/glucose cotransporter), member 11

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC5A11 mRNA

NCBI chr 7:122,813,817...122,873,612
Ensembl chr 7:122,814,003...122,872,476

G

solute carrier family 5, member 4a

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC5A4A mRNA

NCBI chr10:75,983,285...76,025,099
Ensembl chr10:75,983,285...76,025,099

G

solute carrier family 5 (sodium iodide symporter), member 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC5A5 protein

NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401

G

solute carrier family 5 (sodium-dependent vitamin transporter), member 6

multiple interactions

mono-(2-ethylhexyl)phthalate inhibits the reaction [4-phenylbutyric acid results in increased expression of SLC5A6 protein]

NCBI chr 5:31,193,380...31,206,268
Ensembl chr 5:31,193,380...31,206,268

G

solute carrier family 5 (sodium/glucose cotransporter), member 9

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC5A9 mRNA

NCBI chr 4:111,732,571...111,759,993
Ensembl chr 4:111,732,572...111,760,115

G

solute carrier family 6 (neurotransmitter transporter), member 14

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC6A14 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of SLC6A14 mRNA

NCBI chr X:21,581,139...21,608,597
Ensembl chr X:21,581,135...21,608,594

G

solute carrier family 6 (neurotransmitter transporter), member 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC6A15 mRNA

NCBI chr10:103,203,320...103,255,240
Ensembl chr10:103,203,644...103,255,238

G

solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC6A2 mRNA

NCBI chr 8:93,687,100...93,728,295
Ensembl chr 8:93,686,707...93,728,295

G

solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC6A3 mRNA

NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791

G

solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC6A4 mRNA

NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166

G

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC6A9 mRNA

NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC7A10 mRNA

NCBI chr 7:34,885,520...34,900,539
Ensembl chr 7:34,885,810...34,900,539

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 11

increases expression
multiple interactions
decreases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 protein
ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 protein]; HIF1A gene mutant form inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 protein]
RSL3 compound promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of SLC7A11 protein]

PMID:24356939 PMID:34863575 PMID:36438553 PMID:36695872

NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC7A3 mRNA

NCBI chr X:100,122,752...100,134,058
Ensembl chr X:100,122,816...100,129,626

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLC7A9 mRNA

NCBI chr 7:35,148,152...35,165,459
Ensembl chr 7:35,148,221...35,165,461

G

solute carrier family 8 (sodium/lithium/calcium exchanger), member B1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC8B1 mRNA

NCBI chr 5:120,649,233...120,672,089
Ensembl chr 5:120,649,233...120,672,089

G

solute carrier family 9 (sodium/hydrogen exchanger), member 2

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC9A2 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of SLC9A2 mRNA

NCBI chr 1:40,720,872...40,808,045
Ensembl chr 1:40,719,734...40,808,433

G

solute carrier family 9 (sodium/hydrogen exchanger), member 3

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC9A3 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SLC9A3 mRNA

NCBI chr13:74,234,374...74,317,561
Ensembl chr13:74,269,576...74,317,561

G

solute carrier family 9 (sodium/hydrogen exchanger), member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC9A4 mRNA

NCBI chr 1:40,619,146...40,670,188
Ensembl chr 1:40,619,241...40,669,885

G

solute carrier family 9 (sodium/hydrogen exchanger), member 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLC9A9 mRNA

NCBI chr 9:94,551,945...95,112,505
Ensembl chr 9:94,551,962...95,112,498

G

solute carrier organic anion transporter family, member 2b1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLCO2B1 mRNA

NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547

G

solute carrier organic anion transporter family, member 6b1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLCO6B1 mRNA

NCBI chr 1:96,833,901...96,925,285
Ensembl chr 1:96,833,901...96,925,302
Ensembl chr 1:96,833,901...96,925,302

G

schlafen 9

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SLFN11 mRNA

NCBI chr11:82,865,142...82,883,041
Ensembl chr11:82,869,216...82,882,656

G

slit guidance ligand 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLIT1 mRNA

NCBI chr19:41,586,263...41,735,714
Ensembl chr19:41,588,696...41,732,104

G

slit guidance ligand 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SLIT3 mRNA

NCBI chr11:35,012,283...35,599,334
Ensembl chr11:35,012,051...35,599,334

G

SLIT and NTRK-like family, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLITRK1 mRNA

NCBI chr14:109,147,420...109,151,671
Ensembl chr14:109,146,232...109,151,590

G

SLIT and NTRK-like family, member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLITRK2 mRNA

NCBI chr X:65,692,535...65,705,008
Ensembl chr X:65,692,924...65,704,999

G

SLIT and NTRK-like family, member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLITRK4 mRNA

NCBI chr X:63,308,489...63,320,951
Ensembl chr X:63,308,491...63,320,602

G

SLIT and NTRK-like family, member 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SLITRK5 mRNA

NCBI chr14:111,912,547...111,920,576
Ensembl chr14:111,912,529...111,920,573

G

SMAD family member 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SMAD6 mRNA

NCBI chr 9:63,860,358...63,929,374
Ensembl chr 9:63,860,358...63,929,341

G

SMAD family member 7

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of SMAD7 mRNA

NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006

G

structural maintenance of chromosomes 1B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SMC1B mRNA

NCBI chr15:84,948,890...85,016,158
Ensembl chr15:84,948,890...85,016,165

G

smoothened, frizzled class receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Androgens deficiency] results in increased expression of SMO mRNA; mono-(2-ethylhexyl)phthalate inhibits the reaction [cyclopamine results in increased expression of SMO mRNA]

NCBI chr 6:29,735,480...29,761,359
Ensembl chr 6:29,735,502...29,761,364

G

synaptosomal-associated protein 23

multiple interactions

mono-(2-ethylhexyl)phthalate affects the reaction [INS1 protein affects the expression of SNAP23 protein]

NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736

G

synaptosomal-associated protein 25

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SNAP25 mRNA

NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348

G

small nuclear ribonucleoprotein 35 (U11/U12)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SNRNP35 mRNA

NCBI chr 5:124,621,099...124,631,649
Ensembl chr 5:124,621,197...124,629,187

G

syntrophin, basic 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SNTB1 mRNA

NCBI chr15:55,499,784...55,770,707
Ensembl chr15:55,499,784...55,770,345

G

sterol O-acyltransferase 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SOAT2 mRNA

PMID:22401849 PMID:36695872

NCBI chr15:102,058,853...102,071,871
Ensembl chr15:102,058,961...102,071,904

G

suppressor of cytokine signaling 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SOCS2 mRNA

NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042

G

superoxide dismutase 1, soluble

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SOD1 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of SOD1 protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of SOD1 mRNA
Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SOD1 protein]

PMID:20438828 PMID:35861251 PMID:37692514

NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217

G

superoxide dismutase 2, mitochondrial

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SOD2 protein

NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950

G

spermatogenesis and oogenesis specific basic helix-loop-helix 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SOHLH2 mRNA

NCBI chr 3:55,089,465...55,117,378
Ensembl chr 3:55,089,449...55,117,378

G

sorbin and SH3 domain containing 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SORBS2 mRNA

NCBI chr 8:45,960,470...46,280,943
Ensembl chr 8:45,960,825...46,280,943

G

sclerostin domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SOSTDC1 mRNA

NCBI chr12:36,364,168...36,368,451
Ensembl chr12:36,364,138...36,368,451

G

sosondowah ankyrin repeat domain family member B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SOWAHB mRNA

NCBI chr 5:93,188,981...93,192,910
Ensembl chr 5:93,188,982...93,192,881

G

sosondowah ankyrin repeat domain family member D

decreases expression
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SOWAHD mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of SOWAHD mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SOWAHD mRNA

PMID:36189433 PMID:36695872

NCBI chr X:36,312,498...36,314,071
Ensembl chr X:36,312,498...36,314,071

G

SOX2 overlapping transcript (non-protein coding)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SOX2OT mRNA

NCBI chr 3:34,614,530...34,732,142
Ensembl chr 3:34,158,419...34,736,768

G

SRY (sex determining region Y)-box 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SOX3 mRNA

NCBI chr X:59,934,972...59,937,045
Ensembl chr X:59,934,972...59,937,036

G

SRY (sex determining region Y)-box 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SOX6 mRNA

NCBI chr 7:115,070,107...115,639,186
Ensembl chr 7:115,070,107...115,638,031

G

SRY (sex determining region Y)-box 7

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SOX7 mRNA

NCBI chr14:64,181,155...64,188,181
Ensembl chr14:64,181,122...64,188,181

G

SRY (sex determining region Y)-box 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SOX9 mRNA

NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586

G

Sp7 transcription factor 7

decreases expression

mono-(2-ethylhexyl)phthalate analog results in decreased expression of SP7 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of SP7 mRNA

NCBI chr15:102,265,038...102,275,498
Ensembl chr15:102,265,041...102,275,617

G

sperm acrosome associated 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SPACA5 mRNA

NCBI chr X:20,934,669...20,944,197
Ensembl chr X:20,934,645...20,944,202

G

sperm associated antigen 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SPAG1 mRNA

NCBI chr15:36,175,629...36,235,767
Ensembl chr15:36,178,245...36,235,767

G

sperm adhesion molecule 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SPAM1 mRNA

NCBI chr 6:24,791,187...24,801,047
Ensembl chr 6:24,791,187...24,801,047

G

spermatogenesis associated 21

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SPATA21 mRNA

NCBI chr 4:140,815,631...140,840,071
Ensembl chr 4:140,815,644...140,840,071

G

sperm antigen with calponin homology and coiled-coil domains 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of SPECC1 mRNA

NCBI chr11:61,847,589...62,113,839
Ensembl chr11:61,847,589...62,113,839

G

sperm flagellar 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of SPEF1 mRNA

NCBI chr 2:131,012,181...131,016,730
Ensembl chr 2:131,012,181...131,029,202

G

Spi-C transcription factor (Spi-1/PU.1 related)

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SPIC mRNA

NCBI chr10:88,511,131...88,518,885
Ensembl chr10:88,510,634...88,520,877

G

spindlin family, member 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SPIN4 mRNA

NCBI chr X:94,066,113...94,070,288
Ensembl chr X:94,066,116...94,070,288

G

sperm microtubule inner protein 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TEPP mRNA

NCBI chr 8:96,038,148...96,053,239
Ensembl chr 8:96,037,194...96,052,951

G

sialophorin

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SPN mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SPN mRNA

NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995

G

SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SPNS3 mRNA

NCBI chr11:72,388,979...72,441,334
Ensembl chr11:72,385,745...72,441,332

G

SPOC domain containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SPOCD1 mRNA

NCBI chr 4:129,822,560...129,850,908
Ensembl chr 4:129,823,042...129,850,908

G

spondin 2, extracellular matrix protein

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SPON2 mRNA

NCBI chr 5:33,370,862...33,375,596
Ensembl chr 5:33,355,528...33,375,799

G

sprouty RTK signaling antagonist 4

increases expression
decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SPRY4 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SPRY4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SPRY4 mRNA

PMID:16809437 PMID:36189433 PMID:36314267 PMID:36695872

NCBI chr18:38,719,300...38,734,400
Ensembl chr18:38,719,300...38,734,468

G

splA/ryanodine receptor domain and SOCS box containing 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SPSB1 mRNA

NCBI chr 4:149,980,740...150,039,494
Ensembl chr 4:149,980,740...150,039,500

G

spectrin alpha, erythrocytic 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of SPTA1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SPTA1 mRNA

PMID:22401849 PMID:36189433

NCBI chr 1:174,000,305...174,076,015
Ensembl chr 1:174,000,342...174,076,016

G

spectrin beta, non-erythrocytic 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SPTBN2 mRNA

NCBI chr19:4,761,236...4,804,006
Ensembl chr19:4,761,195...4,802,388

G

spectrin beta, non-erythrocytic 4

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SPTBN4 mRNA

NCBI chr 7:27,055,808...27,147,128
Ensembl chr 7:27,055,808...27,147,111

G

spectrin beta, non-erythrocytic 5

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of SPTBN5 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SPTBN5 mRNA

PMID:22401849 PMID:36189433

NCBI chr 2:119,871,974...119,919,394
Ensembl chr 2:119,871,974...119,916,159

G

squalene epoxidase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SQLE mRNA

NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041

G

Rous sarcoma oncogene

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SRC protein

NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782

G

sterol regulatory element binding transcription factor 1

increases expression
multiple interactions
affects expression

mono-(2-ethylhexyl)phthalate results in increased expression of SREBF1 mRNA
[Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of SREBF1 mRNA
mono-(2-ethylhexyl)phthalate affects the expression of SREBF1 mRNA

PMID:23118965 PMID:27181934

NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407

G

sterol regulatory element binding factor 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SREBF2 mRNA

NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580

G

serine/arginine-rich protein specific kinase 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SRPK3 mRNA

NCBI chr X:72,818,011...72,822,531
Ensembl chr X:72,818,011...72,822,531

G

SCO-spondin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SSPO mRNA

NCBI chr 6:48,423,164...48,478,196
Ensembl chr 6:48,425,163...48,478,184

G

somatostatin receptor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SSTR1 mRNA

PMID:22401849 PMID:36695872

NCBI chr12:58,258,524...58,262,822
Ensembl chr12:58,258,558...58,260,673

G

somatostatin receptor 3

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SSTR3 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of SSTR3 mRNA

NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885

G

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ST6GALNAC3 mRNA

NCBI chr 3:152,903,911...153,430,804
Ensembl chr 3:152,903,903...153,430,811

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ST8SIA5 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ST8SIA5 mRNA

PMID:22401849 PMID:36189433

NCBI chr18:77,273,529...77,343,146
Ensembl chr18:77,273,535...77,346,467

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ST8SIA6 mRNA

NCBI chr 2:13,659,745...13,798,659
Ensembl chr 2:13,655,832...13,798,875

G

stabilin 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of STAB2 mRNA

NCBI chr10:86,677,058...86,843,902
Ensembl chr10:86,677,062...86,843,889

G

SH3 and cysteine rich domain 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of STAC2 mRNA

NCBI chr11:97,927,449...97,944,288
Ensembl chr11:97,927,449...97,944,288

G

steroidogenic acute regulatory protein

decreases expression
affects expression
increases activity
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of STAR mRNA
mono-(2-ethylhexyl)phthalate affects the expression of STAR
mono-(2-ethylhexyl)phthalate results in increased activity of STAR protein
mono-(2-ethylhexyl)phthalate results in increased expression of STAR mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of STAR mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of STAR protein
[monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of STAR mRNA; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of STAR protein]; Genistein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of STAR mRNA]; mono-(2-ethylhexyl)phthalate inhibits the reaction [LHB protein results in increased expression of STAR protein]
mono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in decreased expression of STAR mRNA]

PMID:16809437 PMID:19560483 PMID:22087261 PMID:22401849 PMID:22525294 More...

NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010

G

stanniocalcin 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of STC1 mRNA

NCBI chr14:69,266,738...69,278,850
Ensembl chr14:69,266,687...69,279,253

G

stanniocalcin 2

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of STC2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of STC2 mRNA

PMID:36189433 PMID:36695872

NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074

G

STEAP family member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of STEAP4 mRNA

NCBI chr 5:8,010,472...8,032,213
Ensembl chr 5:8,010,457...8,032,213

G

stromal interaction molecule 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of STIM1 mRNA

NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526

G

serine/threonine kinase 32A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of STK32A mRNA

NCBI chr18:43,340,762...43,450,546
Ensembl chr18:43,340,648...43,451,747

G

serine/threonine kinase 32C

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of STK32C mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of STK32C mRNA

NCBI chr 7:138,683,554...138,793,223
Ensembl chr 7:138,683,554...138,793,223

G

stathmin-like 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of STMN2 mRNA

NCBI chr 3:8,574,587...8,626,664
Ensembl chr 3:8,574,420...8,626,666

G

stathmin-like 4

multiple interactions
decreases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of STMN4 mRNA
mono-(2-ethylhexyl)phthalate results in decreased expression of STMN4 mRNA

PMID:36189433 PMID:36314267

NCBI chr14:66,581,806...66,599,129
Ensembl chr14:66,581,745...66,599,129

G

stimulated by retinoic acid gene 8

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Genistein] results in increased expression of STRA8 mRNA; [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of STRA8 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of STRA8 mRNA; mono-(2-ethylhexyl)phthalate results in increased expression of STRA8 protein

PMID:34942354 PMID:36189433 PMID:37364752

NCBI chr 6:34,897,098...34,916,279
Ensembl chr 6:34,897,098...34,916,279

G

stereocilin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of STRC mRNA

NCBI chr 2:121,193,729...121,211,851
Ensembl chr 2:121,194,209...121,217,649

G

striatin interacting protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of STRIP2 mRNA

NCBI chr 6:29,916,975...29,959,680
Ensembl chr 6:29,917,011...29,959,680

G

syntaxin 4A (placental)

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STX4 protein

NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191

G

syntaxin binding protein 3

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STXBP3 protein

NCBI chr 3:108,700,496...108,747,818
Ensembl chr 3:108,700,492...108,747,842

G

syntaxin binding protein 4

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of STXBP4 protein

NCBI chr11:90,367,318...90,528,962
Ensembl chr11:90,367,318...90,528,910

G

syntaxin binding protein 6 (amisyn)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of STXBP6 mRNA

NCBI chr12:44,899,267...45,121,248
Ensembl chr12:44,899,267...45,121,492

G

sulfotransferase family, cytosolic, 2B, member 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SULT2B1 mRNA

NCBI chr 7:45,379,405...45,409,096
Ensembl chr 7:45,379,407...45,434,093

G

sushi domain containing 3

decreases expression
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SUSD3 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of SUSD3 mRNA

NCBI chr13:49,378,993...49,402,197
Ensembl chr13:49,384,166...49,402,182

G

synaptic vesicle glycoprotein 2c

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SV2C mRNA

NCBI chr13:96,091,102...96,270,837
Ensembl chr13:96,091,102...96,269,085

G

synaptonemal complex central element protein 1 like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYCE1L mRNA

NCBI chr 8:114,369,845...114,382,165
Ensembl chr 8:114,369,845...114,382,165

G

syncytin a

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYNA mRNA

NCBI chr 5:134,586,108...134,605,891
Ensembl chr 5:134,587,000...134,589,025

G

spectrin repeat containing, nuclear envelope family member 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SYNE3 mRNA

NCBI chr12:104,896,192...104,976,357
Ensembl chr12:104,896,192...104,976,068

G

synaptogyrin 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SYNGR4 mRNA

NCBI chr 7:45,535,502...45,546,152
Ensembl chr 7:45,534,646...45,546,138

G

synaptoporin

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SYNPR mRNA

NCBI chr14:8,854,294...9,184,983
Ensembl chr14:8,853,423...9,184,983

G

synaptotagmin I

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYT1 mRNA

NCBI chr10:108,333,511...108,846,852
Ensembl chr10:108,333,511...108,846,843

G

synaptotagmin XII

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of SYT12 mRNA

NCBI chr19:4,495,936...4,527,171
Ensembl chr19:4,495,936...4,527,475

G

synaptotagmin XV

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYT15 mRNA

NCBI chr14:33,941,915...33,952,378
Ensembl chr14:33,941,552...33,952,377

G

synaptotagmin II

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYT2 mRNA

NCBI chr 1:134,574,319...134,680,887
Ensembl chr 1:134,574,415...134,690,331

G

synaptotagmin IV

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYT4 mRNA

NCBI chr18:31,570,861...31,580,468
Ensembl chr18:31,570,861...31,580,459

G

synaptotagmin VI

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYT6 mRNA

NCBI chr 3:103,482,561...103,552,883
Ensembl chr 3:103,482,547...103,552,885

G

synaptotagmin VII

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of SYT7 mRNA

NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544

G

synaptotagmin-like 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of SYTL3 mRNA

NCBI chr17:6,925,633...7,005,449
Ensembl chr17:6,926,492...7,005,443

G

synaptotagmin-like 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SYTL5 mRNA

NCBI chr X:9,613,851...9,871,268
Ensembl chr X:9,751,861...9,860,782

G

TATA-box binding protein associated factor 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TAF1 mRNA

NCBI chr X:100,576,335...100,644,635
Ensembl chr X:100,576,340...100,645,395

G

Taf7l2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TAF7L2 mRNA

NCBI chr10:115,947,569...115,949,822
Ensembl chr10:115,948,388...115,949,497
Ensembl chr10:115,948,388...115,949,497

G

TAFA chemokine like family member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM19A2 mRNA

NCBI chr10:123,099,813...123,577,109
Ensembl chr10:123,099,901...123,577,109

G

TAP binding protein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TAPBP mRNA

NCBI chr17:34,138,452...34,148,264
Ensembl chr17:34,134,873...34,148,266

G

TBC1 domain family, member 4

multiple interactions

[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of TBC1D4 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of TBC1D4 protein]

NCBI chr14:101,679,800...101,846,717
Ensembl chr14:101,679,796...101,846,627

G

TBC1 domain family, member 9B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TBC1D9B mRNA

NCBI chr11:50,021,891...50,063,612
Ensembl chr11:50,022,223...50,063,612

G

T-box 22

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TBX22 mRNA

NCBI chr X:106,711,570...106,732,586
Ensembl chr X:106,711,570...106,732,584

G

T-box 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TBX3 mRNA

NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789

G

T-box 3, opposite strand 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TBX3OS1 mRNA

NCBI chr 5:119,708,194...119,809,573
Ensembl chr 5:119,708,195...119,809,430
Ensembl chr 5:119,708,195...119,809,430

G

transcription elongation regulator 1-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TCERG1L mRNA

NCBI chr 7:137,810,701...137,999,459
Ensembl chr 7:137,810,703...137,999,459

G

T cell lymphoma breakpoint 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TCL1 mRNA

NCBI chr12:105,183,012...105,188,996
Ensembl chr12:105,183,009...105,189,052

G

T cell receptor alpha chain

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TCRA mRNA

NCBI chr14:52,665,424...54,461,655

G

L-threonine dehydrogenase

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TDH mRNA

NCBI chr14:63,729,796...63,746,541
Ensembl chr14:63,729,796...63,746,541

G

tudor domain containing 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TDRD5 mRNA

NCBI chr 1:156,082,866...156,131,874
Ensembl chr 1:156,082,866...156,131,234

G

tudor domain containing 9

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TDRD9 mRNA

NCBI chr12:111,937,922...112,035,288
Ensembl chr12:111,937,993...112,035,288

G

trans-2,3-enoyl-CoA reductase-like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TECRL mRNA

NCBI chr 5:83,425,969...83,503,042
Ensembl chr 5:83,425,992...83,503,042

G

thyrotroph embryonic factor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TEF mRNA

NCBI chr15:81,686,874...81,711,064
Ensembl chr15:81,686,622...81,711,064

G

tektin 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TEKT5 mRNA

NCBI chr16:10,175,816...10,213,319
Ensembl chr16:10,175,812...10,213,354

G

teneurin transmembrane protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TENM1 mRNA

NCBI chr X:41,616,743...42,518,045
Ensembl chr X:41,616,743...42,518,003

G

terminal nucleotidyltransferase 5C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM46C mRNA

NCBI chr 3:100,375,373...100,396,508
Ensembl chr 3:100,358,944...100,396,640

G

terminal nucleotidyltransferase 5D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of FAM46D mRNA

NCBI chr X:106,836,196...106,916,517
Ensembl chr X:106,836,196...106,916,515

G

telomere repeat binding bouquet formation protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TERB1 mRNA

NCBI chr 8:105,173,350...105,236,692
Ensembl chr 8:105,173,351...105,236,542

G

telomere repeat binding bouquet formation protein 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TERB2 mRNA

NCBI chr 2:122,016,753...122,036,874
Ensembl chr 2:122,016,753...122,036,878

G

telomeric repeat binding factor 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TRF1 protein

NCBI chr 1:15,875,634...15,914,283
Ensembl chr 1:15,875,870...15,914,276

G

telomerase reverse transcriptase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TERT protein

NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962

G

testis expressed metallothionein like

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TESMIN mRNA

NCBI chr19:3,438,857...3,457,823
Ensembl chr19:3,438,857...3,457,823

G

tet methylcytosine dioxygenase 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TET3 mRNA

NCBI chr 6:83,339,355...83,434,190
Ensembl chr 6:83,339,355...83,436,066

G

testis expressed gene 11

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TEX11 mRNA

NCBI chr X:99,882,254...100,103,245
Ensembl chr X:99,882,254...100,103,273

G

testis expressed 13B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TEX13B mRNA

NCBI chr X:139,709,056...139,714,182
Ensembl chr X:139,709,056...139,714,182

G

TEX13 family member D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TEX13D mRNA

NCBI chr X:41,578,222...41,580,831
Ensembl chr X:41,578,568...41,580,401

G

testis expressed gene 21

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TEX21 mRNA

NCBI chr12:76,245,460...76,293,532
Ensembl chr12:76,245,460...76,293,520

G

transcription factor A, mitochondrial

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TFAM mRNA

NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110

G

transcription factor AP-2, gamma

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TFAP2C mRNA

NCBI chr 2:172,387,599...172,400,542
Ensembl chr 2:172,391,513...172,400,542

G

transcription factor AP-2, epsilon

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TFAP2E mRNA

NCBI chr 4:126,609,796...126,630,062
Ensembl chr 4:126,609,799...126,630,033

G

transcription factor CP2-like 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TFCP2L1 mRNA

NCBI chr 1:118,555,646...118,612,898
Ensembl chr 1:118,555,675...118,612,898

G

transferrin receptor 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TFR2 mRNA

NCBI chr 5:137,568,127...137,586,344
Ensembl chr 5:137,568,102...137,585,743

G

transferrin receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TFRC mRNA

NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612

G

thyroglobulin

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of TG protein
4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of TG protein]

NCBI chr15:66,542,606...66,722,570
Ensembl chr15:66,542,602...66,722,570

G

transforming growth factor alpha

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TGFA mRNA

NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701

G

transforming growth factor, beta 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TGFB2 mRNA

NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186

G

transglutaminase 1, K polypeptide

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TGM1 mRNA

NCBI chr14:55,937,466...55,951,378
Ensembl chr14:55,937,466...55,951,383

G

transglutaminase 2, C polypeptide

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TGM2 mRNA

NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356

G

transglutaminase 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TGM5 mRNA

NCBI chr 2:120,876,591...120,916,322
Ensembl chr 2:120,876,592...120,916,322

G

tyrosine hydroxylase

decreases expression
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of TH mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of TH mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TH mRNA

PMID:21145954 PMID:22401849 PMID:36189433

NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865

G

THAP domain containing 8, pseudogene

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of THAP8 mRNA

NCBI chr 7:29,988,527...29,988,721

G

thrombospondin 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of THBS1 mRNA

NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614

G

thrombospondin, type I, domain containing 7B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of THSD7B mRNA

NCBI chr 1:129,201,010...130,147,015
Ensembl chr 1:129,201,039...130,147,015

G

tissue inhibitor of metalloproteinase 1

decreases expression
multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TIMP1 mRNA
2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]; mifobate inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]; PPARG mRNA promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 mRNA

PMID:22401849 PMID:28416457 PMID:38113427

NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974

G

tissue inhibitor of metalloproteinase 2

decreases expression
multiple interactions
affects expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TIMP2 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of TIMP2 protein
Colforsin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of TIMP2 protein]
mono-(2-ethylhexyl)phthalate affects the expression of TIMP2 mRNA; mono-(2-ethylhexyl)phthalate affects the expression of TIMP2 protein
ESR1 protein affects the reaction [mono-(2-ethylhexyl)phthalate affects the expression of TIMP2 mRNA]

PMID:21832167 PMID:33631300

NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566

G

tubulointerstitial nephritis antigen-like 1

decreases expression
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of TINAGL1 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of TINAGL1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TINAGL1 mRNA

PMID:36189433 PMID:36695872

NCBI chr 4:130,059,393...130,068,915
Ensembl chr 4:130,058,247...130,068,915

G

tight junction protein 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of TJP1 protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of TJP1 protein]; mono-(2-ethylhexyl)phthalate results in decreased expression of and results in decreased localization of TJP1 protein

PMID:18214902 PMID:29940330 PMID:37941498

NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529

G

transketolase-like 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TKTL2 mRNA

NCBI chr 8:66,964,392...66,971,851
Ensembl chr 8:66,964,408...66,970,987

G

TLC domain containing 3B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of FAM57B mRNA

NCBI chr 7:126,413,213...126,429,391
Ensembl chr 7:126,396,840...126,429,391

G

transducin-like enhancer of split 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TLE2 mRNA

NCBI chr10:81,410,573...81,435,018
Ensembl chr10:81,410,395...81,426,679

G

tolloid-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TLL1 mRNA

NCBI chr 8:64,466,132...64,659,043
Ensembl chr 8:64,467,965...64,659,305

G

tolloid-like 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TLL2 mRNA

NCBI chr19:41,069,379...41,199,287
Ensembl chr19:41,071,192...41,195,274

G

toll-like receptor 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TLR2 mRNA

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

G

T cell leukemia, homeobox 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TLX1 mRNA

NCBI chr19:45,138,531...45,145,382
Ensembl chr19:45,139,119...45,145,382

G

transmembrane 6 superfamily member 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TM6SF1 mRNA

NCBI chr 7:81,507,810...81,533,827
Ensembl chr 7:81,508,749...81,534,182

G

transmembrane 7 superfamily member 2

decreases expression
affects expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TM7SF2 mRNA
mono-(2-ethylhexyl)phthalate affects the expression of TM7SF2 mRNA

PMID:22401849 PMID:37364752

NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403

G

transmembrane p24 trafficking protein 5

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TMED5 mRNA

NCBI chr 5:108,269,422...108,280,486
Ensembl chr 5:108,254,232...108,280,486

G

transmembrane protein with EGF-like and two follistatin-like domains 2

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of TMEFF2 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEFF2 mRNA

PMID:36189433 PMID:36695872

NCBI chr 1:50,951,946...51,226,429
Ensembl chr 1:50,939,806...51,226,429

G

transmembrane protein 114

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TMEM114 mRNA

NCBI chr16:8,227,140...8,243,000
Ensembl chr16:8,227,139...8,243,000

G

transmembrane protein 117

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TMEM117 mRNA

NCBI chr15:94,527,066...94,993,978
Ensembl chr15:94,527,113...94,993,979

G

transmembrane protein 130

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TMEM130 mRNA

NCBI chr 5:144,672,725...144,698,388
Ensembl chr 5:144,672,725...144,698,628

G

transmembrane protein 132C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEM132C mRNA

NCBI chr 5:127,318,890...127,642,854
Ensembl chr 5:127,318,872...127,642,857

G

transmembrane protein 145

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TMEM145 mRNA

NCBI chr 7:25,004,981...25,015,621
Ensembl chr 7:25,005,531...25,015,620

G

transmembrane protein 150C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEM150C mRNA

NCBI chr 5:100,225,731...100,313,463
Ensembl chr 5:100,225,731...100,307,667

G

transmembrane protein 154

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TMEM154 mRNA

NCBI chr 3:84,573,499...84,611,882
Ensembl chr 3:84,573,499...84,611,882

G

transmembrane protein 178B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEM178B mRNA

NCBI chr 6:39,848,164...40,232,084
Ensembl chr 6:39,848,395...40,232,084

G

transmembrane protein 200A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TMEM200A mRNA

NCBI chr10:25,867,080...25,955,713
Ensembl chr10:25,788,229...25,954,950

G

transmembrane protein 255A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TMEM255A mRNA

NCBI chr X:37,285,450...37,341,373
Ensembl chr X:37,285,450...37,341,316

G

transmembrane protein 26

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEM26 mRNA

NCBI chr10:68,559,576...68,618,485
Ensembl chr10:68,559,476...68,618,480

G

transmembrane protein 37

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TMEM37 mRNA

NCBI chr 1:119,995,106...120,001,799
Ensembl chr 1:119,995,107...120,001,804

G

transmembrane protein 52

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEM52 mRNA

NCBI chr 4:155,553,571...155,555,315
Ensembl chr 4:155,553,571...155,555,315

G

transmembrane protein 54

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TMEM54 mRNA

NCBI chr 4:128,999,321...129,005,419
Ensembl chr 4:128,999,341...129,005,419

G

transmembrane protein 59-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TMEM59L mRNA

NCBI chr 8:70,936,505...70,939,998
Ensembl chr 8:70,936,517...70,940,008

G

transmembrane protein 62

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TMEM62 mRNA

NCBI chr 2:120,806,959...120,838,333
Ensembl chr 2:120,807,498...120,838,333

G

transmembrane protein 71

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TMEM71 mRNA

NCBI chr15:66,398,061...66,433,085
Ensembl chr15:66,398,061...66,432,952

G

transmembrane protein 72

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEM72 mRNA

NCBI chr 6:116,668,500...116,693,943
Ensembl chr 6:116,656,024...116,693,874

G

transmembrane protein 86A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TMEM86A mRNA

NCBI chr 7:46,700,388...46,704,524
Ensembl chr 7:46,700,349...46,704,525

G

tropomodulin 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMOD1 mRNA

NCBI chr 4:46,038,940...46,116,032
Ensembl chr 4:46,038,935...46,116,032

G

transmembrane protease, serine 15

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TMPRSS15 mRNA

NCBI chr16:78,749,896...78,887,988
Ensembl chr16:78,749,896...78,887,985

G

transmembrane protease, serine 5 (spinesin)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TMPRSS5 mRNA

NCBI chr 9:49,013,994...49,028,891
Ensembl chr 9:48,992,560...49,028,887

G

tumor necrosis factor

increases secretion
increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased secretion of TNF protein
mono-(2-ethylhexyl)phthalate results in increased expression of TNF mRNA
mono-(2-ethylhexyl)phthalate promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF mRNA]

PMID:22143055 PMID:27384973 PMID:29718165

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

tumor necrosis factor, alpha-induced protein 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TNFAIP3 mRNA

NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405

G

tumor necrosis factor alpha induced protein 6

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TNFAIP6 mRNA; mono-(2-ethylhexyl)phthalate results in decreased expression of TNFAIP6 protein

NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698

G

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TNFRSF11A mRNA

NCBI chr 1:105,708,443...105,777,172
Ensembl chr 1:105,708,443...105,775,709

G

tumor necrosis factor receptor superfamily, member 12a

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TNFRSF12A mRNA

NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442

G

tumor necrosis factor receptor superfamily, member 13b

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TNFRSF13B mRNA

NCBI chr11:61,017,567...61,040,435
Ensembl chr11:61,017,581...61,040,198

G

tumor necrosis factor receptor superfamily, member 21

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of TNFRSF21 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TNFRSF21 mRNA

PMID:36189433 PMID:36695872

NCBI chr17:43,327,446...43,400,079
Ensembl chr17:43,327,446...43,400,080

G

tumor necrosis factor receptor superfamily, member 8

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TNFRSF8 mRNA

NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734

G

tumor necrosis factor (ligand) superfamily, member 10

multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of and results in increased methylation of TNFSF10 mRNA

NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576

G

tumor necrosis factor (ligand) superfamily, member 13b

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TNFSF13B mRNA

NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072

G

troponin C2, fast

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TNNC2 mRNA

NCBI chr 2:164,619,081...164,621,654
Ensembl chr 2:164,619,081...164,621,887

G

troponin T1, skeletal, slow

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TNNT1 mRNA

NCBI chr 7:4,507,568...4,518,974
Ensembl chr 7:4,507,569...4,519,381

G

troponin T2, cardiac

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TNNT2 mRNA

NCBI chr 1:135,763,933...135,780,006
Ensembl chr 1:135,764,092...135,779,998

G

tensin 3

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TNS3 mRNA

NCBI chr11:8,381,652...8,614,758
Ensembl chr11:8,381,652...8,614,681

G

tenascin XB

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TNXB mRNA

NCBI chr17:34,879,427...34,938,789
Ensembl chr17:34,879,431...34,938,789

G

TOG array regulator of axonemal microtubules 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TOGARAM2 mRNA

NCBI chr17:71,980,153...72,036,666
Ensembl chr17:71,980,256...72,036,664

G

TOX high mobility group box family member 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TOX2 mRNA

NCBI chr 2:163,045,047...163,166,092
Ensembl chr 2:163,045,045...163,166,090

G

TOX high mobility group box family member 3

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of TOX3 mRNA

NCBI chr 8:90,973,665...91,075,746
Ensembl chr 8:90,973,668...91,074,971

G

trophoblast glycoprotein-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TPBGL mRNA

NCBI chr 7:99,273,274...99,276,310
Ensembl chr 7:99,273,289...99,276,310

G

tropomyosin 1, alpha

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TPM1 mRNA

NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688

G

thyroid peroxidase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TPO protein

NCBI chr12:30,104,658...30,182,983
Ensembl chr12:30,104,658...30,182,623

G

protein-tyrosine sulfotransferase 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TPST2 mRNA

NCBI chr 5:112,424,548...112,463,222
Ensembl chr 5:112,424,557...112,463,227

G

transmembrane phosphatase with tensin homology

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TPTE mRNA

NCBI chr 8:22,773,457...22,861,432
Ensembl chr 8:22,773,457...22,861,434

G

tumor rejection antigen P1A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TRAP1A mRNA

NCBI chr X:138,234,432...138,238,918
Ensembl chr X:138,234,432...138,238,918

G

thyrotropin releasing hormone

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TRH mRNA

NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631

G

tribbles pseudokinase 3

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of TRIB3 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TRIB3 mRNA

PMID:36189433 PMID:36695872

NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952

G

tripartite motif-containing 30B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRIM30B mRNA

NCBI chr 7:104,004,605...104,007,853
Ensembl chr 7:104,004,589...104,019,091

G

tripartite motif-containing 54

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TRIM54 mRNA

NCBI chr 5:31,273,956...31,294,970
Ensembl chr 5:31,274,056...31,294,974

G

tripartite motif-containing 6

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of TRIM6 mRNA

NCBI chr 7:103,868,002...103,884,359
Ensembl chr 7:103,868,000...103,884,359

G

tripartite motif-containing 61

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRIM61 mRNA

NCBI chr 8:65,465,628...65,471,340
Ensembl chr 8:65,465,639...65,471,175

G

tripartite motif-containing 72

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TRIM72 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of TRIM72 mRNA

NCBI chr 7:127,602,684...127,610,565
Ensembl chr 7:127,603,121...127,610,205

G

tripartite motif-containing 9

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRIM9 mRNA

NCBI chr12:70,291,307...70,394,404
Ensembl chr12:70,291,307...70,394,388

G

tripartite motif family-like 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of TRIML1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRIML1 mRNA

NCBI chr 8:43,582,843...43,633,531
Ensembl chr 8:43,582,844...43,594,523

G

tripartite motif family-like 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRIML2 mRNA

NCBI chr 8:43,633,500...43,646,921
Ensembl chr 8:43,633,578...43,646,918

G

tRNA isopentenyltransferase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TRIT1 mRNA

NCBI chr 4:122,910,342...122,948,742
Ensembl chr 4:122,910,390...122,948,742

G

transformation related protein 53

multiple interactions
increases expression
increases activity
decreases response to substance

Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TRP53 protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TRP53 protein]
mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein; mono-(2-ethylhexyl)phthalate results in increased expression of TRP53 protein
mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein
gingerol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TP53 protein]; mono-(2-ethylhexyl)phthalate results in increased phosphorylation of and results in increased expression of TP53 protein; Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of TP53 protein]
TP53 protein results in decreased susceptibility to mono-(2-ethylhexyl)phthalate

PMID:20659492 PMID:21515331 PMID:24706461 PMID:28988496 PMID:36174712

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

transformation related protein 53 inducible nuclear protein 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TRP53INP2 mRNA

NCBI chr 2:155,223,742...155,231,767
Ensembl chr 2:155,222,979...155,231,770

G

transformation related protein 63

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRP63 mRNA

NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852

G

transient receptor potential cation channel, subfamily C, member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRPC4 mRNA

NCBI chr 3:54,063,441...54,225,892
Ensembl chr 3:54,063,456...54,225,892

G

transient receptor potential cation channel, subfamily C, member 6

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRPC6 mRNA

NCBI chr 9:8,543,868...8,680,753
Ensembl chr 9:8,544,143...8,680,742

G

transient receptor potential cation channel, subfamily M, member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TRPM3 mRNA

NCBI chr19:22,114,789...22,972,774
Ensembl chr19:22,116,410...22,972,774

G

transient receptor potential cation channel, subfamily V, member 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TRPV1 mRNA

NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068

G

transient receptor potential cation channel, subfamily V, member 4

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TRPV4 mRNA

NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482

G

tetraspanin 15

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TSPAN15 mRNA

NCBI chr10:62,021,175...62,067,055
Ensembl chr10:62,021,175...62,067,030

G

tetraspanin 32

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TSPAN32 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of TSPAN32 mRNA

NCBI chr 7:142,558,644...142,573,223
Ensembl chr 7:142,558,783...142,573,381

G

tetraspanin 6

affects response to substance

TSPAN6 gene SNP affects the susceptibility to mono-(2-ethylhexyl)phthalate

NCBI chr X:132,791,817...132,801,957
Ensembl chr X:132,791,817...132,799,178

G

tetraspanin 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TSPAN8 mRNA

NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798

G

translocator protein

multiple interactions
increases expression

[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of TSPO mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of TSPO mRNA

NCBI chr15:83,447,774...83,458,404
Ensembl chr15:83,447,793...83,458,404

G

TSPO associated protein 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TSPOAP1 mRNA

NCBI chr11:87,649,022...87,676,754
Ensembl chr11:87,651,367...87,676,754

G

tumor-suppressing subchromosomal transferable fragment 4

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TSSC4 mRNA

NCBI chr 7:142,621,049...142,624,830
Ensembl chr 7:142,622,986...142,624,830

G

Ttc39a opposite strand RNA 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TTC39AOS1 mRNA

NCBI chr 4:109,259,476...109,263,454
Ensembl chr 4:109,259,476...109,263,430

G

tubulin tyrosine ligase-like family, member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TTLL3 mRNA

NCBI chr 6:113,366,221...113,391,553
Ensembl chr 6:113,366,221...113,391,548

G

titin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TTN mRNA

NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891

G

tocopherol (alpha) transfer protein

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of TTPA mRNA

NCBI chr 4:20,007,889...20,030,823
Ensembl chr 4:20,007,938...20,030,785

G

tweety family member 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TTYH2 mRNA

NCBI chr11:114,566,294...114,611,810
Ensembl chr11:114,566,257...114,611,803

G

tubulin, alpha 3A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TUBA3A mRNA

NCBI chr 6:125,255,233...125,263,044
Ensembl chr 6:125,255,237...125,263,005

G

tubulin, alpha 3B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of TUBA3B mRNA

NCBI chr 6:145,561,689...145,567,203
Ensembl chr 6:145,561,483...145,567,205

G

tubulin, beta 6 class V

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TUBB6 mRNA

NCBI chr18:67,523,801...67,535,819
Ensembl chr18:67,523,787...67,535,819

G

taurine upregulated gene 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of TUG1 mRNA

NCBI chr11:3,589,313...3,599,021
Ensembl chr11:3,589,785...3,599,673

G

TXK tyrosine kinase

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TXK mRNA

NCBI chr 5:72,853,321...72,910,337
Ensembl chr 5:72,853,321...72,910,120

G

thioredoxin domain containing 2 (spermatozoa)

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of TXNDC2 mRNA

NCBI chr17:65,944,498...65,955,871
Ensembl chr17:65,944,502...65,949,163

G

thioredoxin interacting protein

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of TXNIP mRNA

NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199

G

thioredoxin reductase 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of TXNRD1 mRNA

NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546

G

UDP-N-acteylglucosamine pyrophosphorylase 1-like 1

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of UAP1L1 mRNA

NCBI chr 2:25,251,501...25,255,695
Ensembl chr 2:25,249,901...25,255,694

G

ubiquitin-associated protein 1-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of UBAP1L mRNA

NCBI chr 9:65,268,311...65,287,659
Ensembl chr 9:65,268,323...65,287,659

G

ubiquitin associated and SH3 domain containing, B

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of UBASH3B mRNA

NCBI chr 9:40,922,056...41,069,358
Ensembl chr 9:40,922,394...41,072,993

G

ubiquitin-conjugating enzyme E2U (putative)

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of UBE2U mRNA

NCBI chr 4:100,336,064...100,407,342
Ensembl chr 4:100,336,046...100,407,344

G

ubiquilin-like

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of UBQLNL mRNA

NCBI chr 7:103,797,466...103,799,763
Ensembl chr 7:103,797,466...103,799,763

G

uncoupling protein 1 (mitochondrial, proton carrier)

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of UCP1 mRNA

NCBI chr 8:84,016,977...84,025,085
Ensembl chr 8:84,016,981...84,025,081

G

UDP glycosyltransferase 1 family, polypeptide A10

increases glucuronidation

UGT1A10 protein results in increased glucuronidation of mono-(2-ethylhexyl)phthalate

NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases glucuronidation

UGT1A3 protein results in increased glucuronidation of mono-(2-ethylhexyl)phthalate

NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719

G

UDP glucuronosyltransferase 1 family, polypeptide A9

increases glucuronidation

UGT1A9 protein results in increased glucuronidation of mono-(2-ethylhexyl)phthalate

NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719

G

UDP glucuronosyltransferase 2 family, polypeptide B34

increases glucuronidation

UGT2B7 protein results in increased glucuronidation of mono-(2-ethylhexyl)phthalate

NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796

G

UDP galactosyltransferase 8A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of UGT8A mRNA

NCBI chr 3:125,655,071...125,732,301
Ensembl chr 3:125,658,920...125,732,268

G

unc-51 like kinase 1

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ULK1 mRNA

NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963

G

unc-13 homolog D

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of UNC13D mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of UNC13D mRNA

PMID:22401849 PMID:36189433

NCBI chr11:115,952,921...115,969,321
Ensembl chr11:115,952,921...115,968,787

G

UPF1 RNA helicase and ATPase

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of UPF1 mRNA

NCBI chr 8:70,784,143...70,806,418
Ensembl chr 8:70,784,175...70,805,928

G

ubiquinol-cytochrome c reductase, complex III subunit XI

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of UQCR11 mRNA

NCBI chr10:80,238,831...80,242,655
Ensembl chr10:80,238,831...80,242,664

G

USH1 protein network component harmonin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of USH1C mRNA

NCBI chr 7:45,844,774...45,887,984
Ensembl chr 7:45,844,774...45,887,927

G

undifferentiated embryonic cell transcription factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of UTF1 mRNA

NCBI chr 7:139,523,769...139,525,025
Ensembl chr 7:139,523,702...139,525,025

G

vascular cell adhesion molecule 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of VCAM1 mRNA

NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337

G

vinculin

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of VCL mRNA

NCBI chr14:20,979,436...21,083,744
Ensembl chr14:20,979,466...21,083,744

G

vitamin D (1,25-dihydroxyvitamin D3) receptor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of VDR mRNA

NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511

G

vascular endothelial growth factor A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of VEGFA mRNA

PMID:36314267 PMID:36695872

NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295

G

vascular endothelial growth factor D

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of VEGFD mRNA

NCBI chr X:163,156,282...163,185,643
Ensembl chr X:163,156,374...163,185,646

G

ventricular zone expressed PH domain-containing 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of VEPH1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of VEPH1 mRNA

PMID:36189433 PMID:36695872

NCBI chr 3:65,960,979...66,204,370
Ensembl chr 3:65,960,979...66,204,258

G

VGF nerve growth factor inducible

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of VGF mRNA

PMID:36695872 PMID:38113427

NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205

G

vimentin

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of VIM mRNA

NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637

G

vasoactive intestinal peptide receptor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of VIPR1 mRNA

NCBI chr 9:121,471,782...121,502,020
Ensembl chr 9:121,471,782...121,502,020

G

very low density lipoprotein receptor

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of VLDLR mRNA

PMID:24356939 PMID:36314267

NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631

G

vomeronasal 2, receptor 12

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of VMN2R12 mRNA

NCBI chr 5:109,233,715...109,245,730
Ensembl chr 5:109,231,690...109,245,816

G

V-set and immunoglobulin domain containing 1

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of VSIG1 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of VSIG1 mRNA

NCBI chr X:139,808,357...139,840,221
Ensembl chr X:139,808,357...139,840,221

G

V-set and transmembrane domain containing 2A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of VSTM2A mRNA

NCBI chr11:16,207,742...16,234,551
Ensembl chr11:16,207,724...16,377,310

G

V-set and transmembrane domain containing 2-like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of VSTM2L mRNA

NCBI chr 2:157,756,573...157,786,639
Ensembl chr 2:157,756,573...157,786,639

G

visual system homeobox 2

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of VSX2 mRNA

NCBI chr12:84,616,602...84,642,231
Ensembl chr12:84,616,536...84,642,231

G

von Willebrand factor A domain containing 3A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of VWA3A mRNA

NCBI chr 7:120,336,554...120,404,769
Ensembl chr 7:120,338,541...120,404,965

G

Von Willebrand factor

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of VWF mRNA

NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642

G

vexin

multiple interactions
increases expression

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of VXN mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of VXN mRNA

NCBI chr 1:9,671,492...9,697,367
Ensembl chr 1:9,671,424...9,697,368

G

WW domain binding protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of WBP2 mRNA

NCBI chr11:115,969,397...115,977,821
Ensembl chr11:115,969,399...115,977,821

G

WBP2 N-terminal like

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WBP2NL mRNA

NCBI chr15:82,183,126...82,198,848
Ensembl chr15:82,183,155...82,198,824

G

WD repeat domain 17

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of WDR17 mRNA

NCBI chr 8:55,082,316...55,180,014
Ensembl chr 8:55,082,090...55,340,219

G

WD repeat domain 25

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WDR25 mRNA

NCBI chr12:108,860,155...108,994,380
Ensembl chr12:108,859,557...108,994,378

G

WD repeat domain 6

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of WDR6 mRNA

NCBI chr 9:108,449,510...108,455,862
Ensembl chr 9:108,449,510...108,455,938

G

WD repeat domain 64

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of WDR64 mRNA

NCBI chr 1:175,526,135...175,643,300
Ensembl chr 1:175,526,159...175,643,300

G

WAP four-disulfide core domain 10

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of WFDC10 mRNA

NCBI chr 2:164,497,966...164,499,288
Ensembl chr 2:164,497,966...164,499,288

G

WAP four-disulfide core domain 15A

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WFDC15A mRNA

NCBI chr 2:164,040,783...164,042,058
Ensembl chr 2:164,040,783...164,042,050

G

WAP four-disulfide core domain 18

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WFDC18 mRNA

NCBI chr11:83,599,830...83,602,186
Ensembl chr11:83,599,841...83,602,174

G

WAP four-disulfide core domain 2

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of WFDC2 mRNA

NCBI chr 2:164,404,635...164,410,430
Ensembl chr 2:164,404,333...164,410,430

G

WAP four-disulfide core domain 8

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of WFDC8 mRNA

NCBI chr 2:164,438,378...164,455,545
Ensembl chr 2:164,438,378...164,455,546

G

Wnt inhibitory factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WIF1 mRNA

NCBI chr10:120,869,909...120,936,547
Ensembl chr10:120,869,865...120,936,555

G

WNK lysine deficient protein kinase 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of WNK2 mRNA

NCBI chr13:49,189,778...49,302,110
Ensembl chr13:49,189,779...49,301,490

G

wingless-type MMTV integration site family, member 10A

decreases expression
affects expression

mono-(2-ethylhexyl)phthalate results in decreased expression of WNT10A protein
mono-(2-ethylhexyl)phthalate affects the expression of WNT10A mRNA

NCBI chr 1:74,831,178...74,843,335
Ensembl chr 1:74,830,675...74,843,338

G

wingless-type MMTV integration site family, member 3

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of WNT3 mRNA

NCBI chr11:103,665,000...103,708,854
Ensembl chr11:103,664,976...103,708,783

G

wingless-type MMTV integration site family, member 4

multiple interactions
increases expression

mono-(2-ethylhexyl)phthalate promotes the reaction [Tretinoin results in increased expression of WNT4 mRNA]
mono-(2-ethylhexyl)phthalate results in increased expression of WNT4 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WNT4 mRNA

PMID:30476341 PMID:36189433

NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037

G

wingless-type MMTV integration site family, member 8A

affects expression
multiple interactions

mono-(2-ethylhexyl)phthalate affects the expression of WNT8A mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WNT8A mRNA

PMID:21195148 PMID:36189433

NCBI chr18:34,675,380...34,681,114
Ensembl chr18:34,675,366...34,681,326

G

wingless-type MMTV integration site family, member 9A

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of WNT9A protein

NCBI chr11:59,197,675...59,224,378
Ensembl chr11:59,197,754...59,224,378

G

WT1 transcription factor, opposite strand

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of WT1OS mRNA

NCBI chr 2:104,906,883...104,956,855
Ensembl chr 2:104,906,883...104,956,855

G

WT1 associating protein

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of WTAP mRNA

NCBI chr17:13,185,686...13,211,430
Ensembl chr17:13,185,683...13,213,056

G

XIAP associated factor 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of XAF1 mRNA

NCBI chr11:72,192,229...72,204,560
Ensembl chr11:72,192,455...72,204,559

G

X-box binding protein 1

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in increased localization of XBP1 protein alternative form; Toyocamycin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]

NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893

G

X-linked Kx blood group related, X-linked

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of XKRX mRNA

NCBI chr X:133,049,786...133,086,747
Ensembl chr X:133,049,792...133,062,825

G

X-linked lymphocyte-regulated 4B

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of XLR4B mRNA

NCBI chr X:72,257,928...72,266,059
Ensembl chr X:72,257,939...72,266,059

G

X-linked lymphocyte-regulated 4C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of XLR4C mRNA

NCBI chr X:72,277,682...72,286,736
Ensembl chr X:72,277,294...72,286,736

G

yes-associated protein 1

increases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 mRNA
IRF1 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 mRNA]; IRF1 protein promotes the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of YAP1 protein]; LATS1 protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased stability of YAP1 protein]; mono-(2-ethylhexyl)phthalate results in increased expression of and results in decreased phosphorylation of and results in increased activity of and affects the localization of and results in increased stability of YAP1 protein

NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597

G

YTH domain containing 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of YTHDC1 mRNA

NCBI chr 5:86,951,349...86,984,518
Ensembl chr 5:86,952,080...86,984,518

G

YTH domain containing 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of YTHDC2 mRNA

NCBI chr18:44,961,521...45,022,782
Ensembl chr18:44,960,813...45,022,791

G

YTH N6-methyladenosine RNA binding protein 1

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of YTHDF1 mRNA

NCBI chr 2:180,546,170...180,562,729
Ensembl chr 2:180,546,170...180,562,742

G

YTH N6-methyladenosine RNA binding protein 2

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of YTHDF2 mRNA

NCBI chr 4:131,912,227...131,939,567
Ensembl chr 4:131,912,223...131,939,614

G

YTH N6-methyladenosine RNA binding protein 3

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of YTHDF3 mRNA

NCBI chr 3:16,237,309...16,271,201
Ensembl chr 3:16,237,376...16,271,201

G

zonadhesin

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ZAN mRNA

NCBI chr 5:137,376,899...137,475,326
Ensembl chr 5:137,376,899...137,475,326

G

zygote arrest 1

decreases expression
multiple interactions

mono-(2-ethylhexyl)phthalate results in decreased expression of ZAR1 mRNA
[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ZAR1 mRNA

NCBI chr 5:72,734,457...72,738,427
Ensembl chr 5:72,734,149...72,738,597

G

zinc finger and BTB domain containing 16

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ZBTB16 mRNA
mono-(2-ethylhexyl)phthalate results in increased expression of PLZF protein

PMID:16809437 PMID:37364752

NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522

G

zinc finger and BTB domain containing 7B

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ZBTB7B mRNA

NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083

G

zinc finger and BTB domain containing 7C

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZBTB7C mRNA

NCBI chr18:75,953,249...76,281,635
Ensembl chr18:75,953,249...76,281,635

G

zinc finger CCCH type containing 12A

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ZC3H12A mRNA

NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633

G

zinc finger, CCHC domain containing 18

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of ZCCHC18 mRNA

NCBI chr X:135,893,128...135,899,221
Ensembl chr X:135,893,904...135,899,221

G

zinc finger and AT hook domain containing

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ZFAT mRNA

NCBI chr15:67,955,563...68,130,771
Ensembl chr15:67,955,613...68,130,705

G

zinc finger protein 185

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of ZFP185 mRNA

NCBI chr X:72,030,860...72,075,149
Ensembl chr X:72,030,945...72,075,149

G

zinc finger protein 27

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ZFP27 mRNA

NCBI chr 7:29,592,762...29,605,976
Ensembl chr 7:29,592,758...29,605,997

G

zinc finger protein 36

increases expression

mono-(2-ethylhexyl)phthalate results in increased expression of ZFP36 mRNA

NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678

G

zinc finger protein 36, C3H type-like 1, pseudogene

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZFP36L1-PS mRNA

NCBI chr X:37,269,486...37,270,700
Ensembl chr X:37,269,605...37,270,503

G

zinc finger protein 488

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZFP488 mRNA

NCBI chr14:33,689,023...33,700,986
Ensembl chr14:33,689,027...33,700,721

G

zinc finger protein 52

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ZFP52 mRNA

NCBI chr17:21,755,801...21,783,624
Ensembl chr17:21,755,801...21,782,863

G

zinc finger protein 771

affects expression

mono-(2-ethylhexyl)phthalate affects the expression of ZFP771 mRNA

NCBI chr 7:126,842,168...126,854,044
Ensembl chr 7:126,843,446...126,853,975

G

zinc finger protein 831

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ZFP831 mRNA

NCBI chr 2:174,440,453...174,552,625
Ensembl chr 2:174,485,327...174,552,625

G

zymogen granule protein 16

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of ZG16 mRNA

NCBI chr 7:126,649,328...126,651,847
Ensembl chr 7:126,649,328...126,686,500

G

zinc finger protein of the cerebellum 5

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZIC5 mRNA

NCBI chr14:122,696,572...122,703,127
Ensembl chr14:122,694,207...122,703,089

G

zinc finger, imprinted 1

multiple interactions

[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZIM1 mRNA

NCBI chr 7:6,677,443...6,699,521
Ensembl chr 7:6,674,268...6,699,449

G

zinc finger, MYND domain containing 10

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ZMYND10 mRNA

NCBI chr 9:107,424,067...107,428,520
Ensembl chr 9:107,424,497...107,428,518

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zinc finger, MYND-type containing 15

decreases expression

mono-(2-ethylhexyl)phthalate results in decreased expression of ZMYND15 mRNA

NCBI chr11:70,350,259...70,357,028
Ensembl chr11:70,350,259...70,357,028

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	22194
role	22179
biological role	22178
biochemical role	21449
volatile oil component	7813
2-ethylhexan-1-ol	1999
mono(2-ethylhexyl) phthalate	1991
Path 2
Term	Annotations
CHEBI ontology	22194
subatomic particle	22186
composite particle	22186
hadron	22186
baryon	22186
nucleon	22186
atomic nucleus	22186
atom	22186
main group element atom	22120
p-block element atom	22120
carbon group element atom	21920
carbon atom	21846
organic molecular entity	21846
heteroorganic entity	21500
organochalcogen compound	20983
organooxygen compound	20824
carbon oxoacid	19606
carboxylic acid	19602
aromatic carboxylic acid	12760
benzoic acids	12738
benzenedicarboxylic acid	8798
phthalic acid	8561
phthalate ester	8561
phthalic acid monoester	2357
mono(2-ethylhexyl) phthalate	1991

paths to the root