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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:CDP
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Accession:CHEBI:17239 term browser browse the term
Definition:A pyrimidine ribonucleoside 5'-diphosphate having cytosine as the nucleobase.
Synonyms:related_synonym: 5'-CDP;   Cytidine 5'-diphosphate;   Cytidine 5'-diphosphoric acid;   Cytidine 5'-pyrophosphate;   Cytidine diphosphate;   Cytidine, 5'-(trihydrogen pyrophosphate);   Formula=C9H15N3O11P2;   InChI=1S/C9H15N3O11P2/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1;   InChIKey=ZWIADYZPOWUWEW-XVFCMESISA-N;   SMILES=Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1;   cytidine 5'-(trihydrogen diphosphate)
 alt_id: CHEBI:13254;   CHEBI:23519;   CHEBI:3260;   CHEBI:41451
 xref: CAS:63-38-7;   DrugBank:DB04555;   KEGG:C00112;   PDBeChem:CDF;   PDBeChem:CDP
 cyclic_relationship: is_conjugate_acid_of CHEBI:58069


show annotations for term's descendants           Sort by:
CDP-choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of CASP3 protein CTD PMID:12443983 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA CTD PMID:16193989 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions EXP NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor] CTD PMID:18164358 NCBI chr 3:27,237,153...27,299,112
Ensembl chr 3:27,237,114...27,338,757 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form CTD PMID:12443983 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions		 ISO Cytidine Diphosphate Choline results in increased expression of SIRT1 protein
Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein		 CTD PMID:23600725 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biochemical role 21431
          metabolite 21379
            prokaryotic metabolite 19224
              bacterial metabolite 19198
                Escherichia coli metabolite 19094
                  CDP 5
                    2'-deoxy-5-hydroxymethyl-CDP 0
                    CDP-1L-myo-inositol 0
                    CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol 0
                    CDP-choline 5
                    CDP-sugar + 0
                    dCDP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      chalcogen 21431
                        oxygen atom 21437
                          oxygen molecular entity 21409
                            hydroxides 20789
                              oxoacid 20101
                                pnictogen oxoacid 13699
                                  phosphorus oxoacid 12721
                                    phosphoric acids 11722
                                      phosphoric acid 11710
                                        phosphoric acid derivative 11512
                                          phosphate 11511
                                            organic phosphate 11511
                                              carbohydrate phosphate 1855
                                                phospho sugar 1703
                                                  aldose phosphate 1701
                                                    aldopentose phosphate 1693
                                                      ribose phosphate 1685
                                                        ribonucleotide 1645
                                                          ribonucleoside 5'-phosphate 641
                                                            ribonucleoside 5'-diphosphate 115
                                                              pyrimidine ribonucleoside 5'-diphosphate 24
                                                                CDP 5
                                                                  2'-deoxy-5-hydroxymethyl-CDP 0
                                                                  CDP-1L-myo-inositol 0
                                                                  CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol 0
                                                                  CDP-choline 5
                                                                  CDP-sugar + 0
                                                                  dCDP 0
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