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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:CDP
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Accession:CHEBI:17239 term browser browse the term
Definition:A pyrimidine ribonucleoside 5'-diphosphate having cytosine as the nucleobase.
Synonyms:related_synonym: 5'-CDP;   Cytidine 5'-diphosphate;   Cytidine 5'-diphosphoric acid;   Cytidine 5'-pyrophosphate;   Cytidine diphosphate;   Cytidine, 5'-(trihydrogen pyrophosphate);   Formula=C9H15N3O11P2;   InChI=1S/C9H15N3O11P2/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1;   InChIKey=ZWIADYZPOWUWEW-XVFCMESISA-N;   SMILES=Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1;   cytidine 5'-(trihydrogen diphosphate)
 alt_id: CHEBI:13254;   CHEBI:23519;   CHEBI:3260;   CHEBI:41451
 xref: CAS:63-38-7;   DrugBank:DB04555;   KEGG:C00112;   PDBeChem:CDF;   PDBeChem:CDP
 cyclic_relationship: is_conjugate_acid_of CHEBI:58069



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CDP-choline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of CASP3 protein CTD PMID:12443983 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Cytidine Diphosphate Choline results in decreased expression of ICAM1 mRNA CTD PMID:16193989 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO NCEH1 protein inhibits the reaction [[Chlorpyrifos metabolite co-treated with Cytidine Diphosphate Choline] results in increased abundance of Platelet Activating Factor] CTD PMID:18164358 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form CTD PMID:12443983 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions
EXP Cytidine Diphosphate Choline results in increased expression of SIRT1 protein
Cytidine Diphosphate Choline results in increased expression of and results in increased activity of SIRT1 protein
CTD PMID:23600725 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        biochemical role 19671
          metabolite 19631
            prokaryotic metabolite 18629
              bacterial metabolite 18654
                Escherichia coli metabolite 18549
                  CDP 5
                    2'-deoxy-5-hydroxymethyl-CDP 0
                    CDP-1L-myo-inositol 0
                    CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol 0
                    CDP-choline 5
                    CDP-sugar + 0
                    dCDP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      chalcogen 19732
                        oxygen atom 19674
                          oxygen molecular entity 19674
                            hydroxides 19454
                              oxoacid 18744
                                pnictogen oxoacid 11007
                                  phosphorus oxoacid 9818
                                    phosphoric acids 8644
                                      phosphoric acid 8639
                                        phosphoric acid derivative 8348
                                          phosphate 8348
                                            organic phosphate 8342
                                              carbohydrate phosphate 1832
                                                phospho sugar 1680
                                                  aldose phosphate 1678
                                                    aldopentose phosphate 1670
                                                      ribose phosphate 1664
                                                        ribonucleotide 1623
                                                          ribonucleoside 5'-phosphate 626
                                                            ribonucleoside 5'-diphosphate 111
                                                              pyrimidine ribonucleoside 5'-diphosphate 21
                                                                CDP 5
                                                                  2'-deoxy-5-hydroxymethyl-CDP 0
                                                                  CDP-1L-myo-inositol 0
                                                                  CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol 0
                                                                  CDP-choline 5
                                                                  CDP-sugar + 0
                                                                  dCDP 0
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