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ONTOLOGY REPORT - ANNOTATIONS


Term:4-methylumbelliferone
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Accession:CHEBI:17224 term browser browse the term
Definition:A hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4.
Synonyms:exact_synonym: 7-hydroxy-4-methyl-2H-chromen-2-one
 related_synonym: 4-MU;   4-Methyl-7-hydroxycoumarin;   7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran;   7-Hydroxy-4-methyl-2-oxo-3-chromene;   7-Hydroxy-4-methyl-2H-1-benzopyran-2-one;   7-Hydroxy-4-methylcoumarin;   Formula=C10H8O3;   Hymecromone;   Imecromone;   InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3;   InChIKey=HSHNITRMYYLLCV-UHFFFAOYSA-N;   SMILES=C1=2OC(=O)C=C(C1=CC=C(C2)O)C;   beta-Methylumbelliferone;   himecromona;   hymecromonum
 alt_id: CHEBI:110550;   CHEBI:12030;   CHEBI:1903;   CHEBI:20452
 xref: Beilstein:142217 "Beilstein";   CAS:90-33-5 "ChemIDplus";   CAS:90-33-5 "KEGG COMPOUND";   CAS:90-33-5 "NIST Chemistry WebBook";   Drug_Central:1401 "DrugCentral";   Gmelin:165817 "Gmelin";   HMDB:HMDB0059622;   KEGG:C03081;   KEGG:D00170;   LINCS:LSM-3025
 xref_mesh: MESH:D006923
 xref: MetaCyc:CPD-182;   PDBeChem:4MU;   PMID:12419303 "Europe PMC";   PMID:1650428 "Europe PMC";   PMID:17470403 "Europe PMC";   PMID:20332231 "Europe PMC";   PMID:23124556 "Europe PMC";   PMID:23228386 "Europe PMC";   PMID:24080584 "Europe PMC";   PMID:26548718 "Europe PMC";   Reaxys:142217 "Reaxys";   Wikipedia:Hymecromone


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4-methylumbelliferone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:6480464
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C JBrowse link 9 95,233,957 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 JBrowse link 14 22,192,970 22,217,094 RGD:6480464
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 JBrowse link 14 22,375,428 22,486,291 RGD:6480464
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 14 22,724,399 22,736,148 RGD:6480464
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 14 22,597,103 22,619,968 RGD:6480464
4-methylumbelliferone sulfate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a25 solute carrier family 22, member 25 JBrowse link 1 224,596,886 224,698,512 RGD:6480464
4-methylumbelliferyl beta-D-galactoside term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ca12 carbonic anhydrase 12 JBrowse link 8 72,405,770 72,461,425 RGD:6480464
G Ca9 carbonic anhydrase 9 JBrowse link 5 59,008,277 59,015,535 RGD:6480464
4-methylumbelliferyl beta-D-glucoside term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gaa glucosidase, alpha, acid JBrowse link 10 108,395,873 108,412,999 RGD:6480464
coumaphos term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 14 10,343,287 10,396,565 RGD:6480464
G Lif LIF, interleukin 6 family cytokine JBrowse link 14 84,482,652 84,500,574 RGD:6480464
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        inhibitor 18059
          hyaluronic acid synthesis inhibitor 24
            4-methylumbelliferone 24
              4-methylumbelliferone beta-D-glucuronide 0
              4-methylumbelliferone sulfate 1
              4-methylumbelliferyl alpha-D-galactoside 0
              4-methylumbelliferyl alpha-L-arabinoside 0
              4-methylumbelliferyl beta-D-galactoside 2
              4-methylumbelliferyl beta-D-glucoside 1
              4-methylumbelliferyl butyate 0
              chlorferron + 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  oxacycle 16945
                                    benzopyran 9428
                                      1-benzopyran 9120
                                        chromenes 894
                                          chromenone 817
                                            coumarins 533
                                              hydroxycoumarin 289
                                                umbelliferone 79
                                                  4-methylumbelliferone 24
                                                    4-methylumbelliferone beta-D-glucuronide 0
                                                    4-methylumbelliferone sulfate 1
                                                    4-methylumbelliferyl alpha-D-galactoside 0
                                                    4-methylumbelliferyl alpha-L-arabinoside 0
                                                    4-methylumbelliferyl beta-D-galactoside 2
                                                    4-methylumbelliferyl beta-D-glucoside 1
                                                    4-methylumbelliferyl butyate 0
                                                    chlorferron + 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.