Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:geranyl diphosphate
go back to main search page
Accession:CHEBI:17211 term browser browse the term
Definition:The diphosphate of the polyprenol compound geraniol.
Synonyms:related_synonym: (2E)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate;   Formula=C10H20O7P2;   InChI=1S/C10H20O7P2/c1-9(2)5-4-6-10(3)7-8-16-19(14,15)17-18(11,12)13/h5,7H,4,6,8H2,1-3H3,(H,14,15)(H2,11,12,13)/b10-7+;   InChIKey=GVVPGTZRZFNKDS-JXMROGBWSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\COP(O)(=O)OP(O)(O)=O;   geranyl pyrophosphate
 alt_id: CHEBI:14299;   CHEBI:24223;   CHEBI:42877;   CHEBI:5332
 xref: Beilstein:1915690;   CAS:763-10-0;   DrugBank:DB02552;   KEGG:C00341;   KNApSAcK:C00000846;   LIPID_MAPS_instance:LMPR0102010001
 xref_mesh: MESH:C015234
 xref: PDBeChem:GPP;   PMID:19049370;   PMID:19856009;   PMID:23607888;   PMID:7753173;   Reaxys:1915690
 cyclic_relationship: is_conjugate_acid_of CHEBI:58057


show annotations for term's descendants           Sort by:
 
geranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases abundance
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate] CTD PMID:19819230 PMID:19856009 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO geranyl diphosphate results in decreased activity of MVK protein
geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form CTD PMID:19819230 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        fragrance 899
          geraniol 387
            geranyl diphosphate 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      chalcogen 19469
                        oxygen atom 19445
                          oxygen molecular entity 19445
                            hydroxides 19180
                              oxoacid 18498
                                pnictogen oxoacid 10685
                                  phosphorus oxoacid 9666
                                    phosphoric acids 8466
                                      phosphoric acid 8466
                                        phosphoric acid derivative 8172
                                          phosphate 8172
                                            organic phosphate 8171
                                              phospholipid 302
                                                isoprenoid phosphate 75
                                                  prenol phosphate 75
                                                    polyprenol phosphate 66
                                                      polyprenyl diphosphate 66
                                                        geranyl diphosphate 3
paths to the root