Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:geranyl diphosphate
go back to main search page
Accession:CHEBI:17211 term browser browse the term
Definition:The diphosphate of the polyprenol compound geraniol.
Synonyms:related_synonym: (2E)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate;   Formula=C10H20O7P2;   InChI=1S/C10H20O7P2/c1-9(2)5-4-6-10(3)7-8-16-19(14,15)17-18(11,12)13/h5,7H,4,6,8H2,1-3H3,(H,14,15)(H2,11,12,13)/b10-7+;   InChIKey=GVVPGTZRZFNKDS-JXMROGBWSA-N;   SMILES=CC(C)=CCC\\C(C)=C\\COP(O)(=O)OP(O)(O)=O;   geranyl pyrophosphate
 alt_id: CHEBI:14299;   CHEBI:24223;   CHEBI:42877;   CHEBI:5332
 xref: Beilstein:1915690;   CAS:763-10-0;   DrugBank:DB02552;   KEGG:C00341;   KNApSAcK:C00000846;   LIPID_MAPS_instance:LMPR0102010001
 xref_mesh: MESH:C015234
 xref: PDBeChem:GPP;   PMID:19049370;   PMID:19856009;   PMID:23607888;   PMID:7753173;   Reaxys:1915690
 cyclic_relationship: is_conjugate_acid_of CHEBI:58057


show annotations for term's descendants           Sort by:
 
geranyl diphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases abundance
ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of HMGCR protein; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate] CTD PMID:19819230 PMID:19856009 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Mvk mevalonate kinase decreases activity
multiple interactions
ISO geranyl diphosphate results in decreased activity of MVK protein
geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased phosphorylation of Mevalonic Acid]
CTD PMID:9392419 NCBI chr12:47,904,266...47,920,457
Ensembl chr12:47,904,719...47,919,400
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO [geranylgeraniol co-treated with geranyl pyrophosphate] results in decreased expression of RAP1A protein modified form CTD PMID:19819230 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        fragrance 854
          geraniol 386
            geranyl diphosphate 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      chalcogen 19391
                        oxygen atom 19353
                          oxygen molecular entity 19353
                            hydroxides 19103
                              oxoacid 18235
                                pnictogen oxoacid 10181
                                  phosphorus oxoacid 9072
                                    phosphoric acids 7831
                                      phosphoric acid 7831
                                        phosphoric acid derivative 7511
                                          phosphate 7511
                                            organic phosphate 7510
                                              phospholipid 290
                                                isoprenoid phosphate 72
                                                  prenol phosphate 72
                                                    polyprenol phosphate 63
                                                      polyprenyl diphosphate 63
                                                        geranyl diphosphate 3
paths to the root