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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dihydrosanguinarine
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Accession:CHEBI:17209 term browser browse the term
Definition:A benzophenanthridine alkaloid obtained by selective hydrogenation of the 13,14-position of sanguinarine.
Synonyms:exact_synonym: 13-methyl-13,14-dihydro-2H,10H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine
 related_synonym: 13,14-dihydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine;   Formula=C20H15NO4;   InChI=1S/C20H15NO4/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21/h2-7H,8-10H2,1H3;   InChIKey=CIUHLXZTZWTVFL-UHFFFAOYSA-N;   SMILES=CN1Cc2c3OCOc3ccc2-c2ccc3cc4OCOc4cc3c12;   dihydroavicine
 alt_id: CHEBI:14161;   CHEBI:23766;   CHEBI:4584
 xref: CAS:3606-45-9;   KEGG:C05191;   KNApSAcK:C00001847;   KNApSAcK:C00024647
 xref_mesh: MESH:C501843
 xref: PMID:11488455;   PMID:11488467;   PMID:12898646;   PMID:17260290;   PMID:18309269;   PMID:18420297;   PMID:18495316;   PMID:19346183;   PMID:19578993;   PMID:19629460;   PMID:19647059;   PMID:19873781;   PMID:20226485;   PMID:20385218;   PMID:20600683;   PMID:20683512;   PMID:20686258;   PMID:21500094;   Reaxys:48770



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dihydrosanguinarine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO dihydrosanguinarine results in increased activity of CASP3 protein CTD PMID:19346183 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO dihydrosanguinarine results in increased activity of CASP9 protein CTD PMID:19346183 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases chemical synthesis EXP NQO1 protein results in increased chemical synthesis of dihydrosanguinarine CTD PMID:24300172 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19763
      biological role 19763
        biochemical role 19380
          metabolite 19358
            dihydrosanguinarine 3
              dihydrochelirubine 0
              dihydromacarpine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19710
                    p-block element atom 19710
                      carbon group element atom 19631
                        carbon atom 19621
                          organic molecular entity 19621
                            organic molecule 19562
                              organic cyclic compound 19356
                                organic heterocyclic compound 18596
                                  organonitrogen heterocyclic compound 17669
                                    benzophenanthridine 122
                                      benzophenanthridine alkaloid 99
                                        sanguinarine 51
                                          dihydrosanguinarine 3
                                            dihydrochelirubine 0
                                            dihydromacarpine 0
paths to the root