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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dihydrosanguinarine
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Accession:CHEBI:17209 term browser browse the term
Definition:A benzophenanthridine alkaloid obtained by selective hydrogenation of the 13,14-position of sanguinarine.
Synonyms:exact_synonym: 13-methyl-13,14-dihydro-2H,10H-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine
 related_synonym: 13,14-dihydro-13-methyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine;   Formula=C20H15NO4;   InChI=1S/C20H15NO4/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21/h2-7H,8-10H2,1H3;   InChIKey=CIUHLXZTZWTVFL-UHFFFAOYSA-N;   SMILES=CN1Cc2c3OCOc3ccc2-c2ccc3cc4OCOc4cc3c12;   dihydroavicine
 alt_id: CHEBI:14161;   CHEBI:23766;   CHEBI:4584
 xref: CAS:3606-45-9;   KEGG:C05191;   KNApSAcK:C00001847;   KNApSAcK:C00024647
 xref_mesh: MESH:C501843
 xref: PMID:11488455;   PMID:11488467;   PMID:12898646;   PMID:17260290;   PMID:18309269;   PMID:18420297;   PMID:18495316;   PMID:19346183;   PMID:19578993;   PMID:19629460;   PMID:19647059;   PMID:19873781;   PMID:20226485;   PMID:20385218;   PMID:20600683;   PMID:20683512;   PMID:20686258;   PMID:21500094;   Reaxys:48770


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dihydrosanguinarine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO dihydrosanguinarine results in increased activity of CASP3 protein CTD PMID:19346183 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO dihydrosanguinarine results in increased activity of CASP9 protein CTD PMID:19346183 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases chemical synthesis EXP NQO1 protein results in increased chemical synthesis of dihydrosanguinarine CTD PMID:24300172 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            dihydrosanguinarine 3
              dihydrochelirubine 0
              dihydromacarpine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic heterocyclic compound 18407
                                  organonitrogen heterocyclic compound 17460
                                    benzophenanthridine 119
                                      benzophenanthridine alkaloid 96
                                        sanguinarine 51
                                          dihydrosanguinarine 3
                                            dihydrochelirubine 0
                                            dihydromacarpine 0
paths to the root

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