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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:L-isoleucine
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Accession:CHEBI:17191 term browser browse the term
Definition:The L-enantiomer of isoleucine.
Synonyms:related_synonym: (2S,3S)-2-amino-3-methylpentanoic acid;   2-Amino-3-methylvaleric acid;   Formula=C6H13NO2;   I;   ISOLEUCINE;   Ile;   InChI=1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1;   InChIKey=AGPKZVBTJJNPAG-WHFBIAKZSA-N;   SMILES=OC([C@H]([C@H](CC)C)N)=O;   alpha-amino-beta-methylvaleric acid
 alt_id: CHEBI:13127;   CHEBI:21344;   CHEBI:43290;   CHEBI:43342;   CHEBI:43366;   CHEBI:6255
 xref: Beilstein:1721792;   CAS:73-32-5;   DrugBank:DB00167;   Drug_Central:4129;   ECMDB:ECMDB00172;   Gmelin:486381;   HMDB:HMDB0000172;   KEGG:C00407;   KEGG:D00065;   KNApSAcK:C00001374
 xref_mesh: MESH:D007532
 xref: MetaCyc:ILE;   PDBeChem:ILE;   PMID:14651987;   PMID:16140883;   PMID:17299083;   PMID:17409434;   PMID:22298573;   PMID:24284437;   PMID:24406630;   PMID:24738868;   PMID:24831709;   Reaxys:1721792;   Wikipedia:Isoleucine;   YMDB:YMDB00038
 cyclic_relationship: is_conjugate_acid_of CHEBI:32604;   is_conjugate_base_of CHEBI:32605;   is_enantiomer_of CHEBI:27730;   is_tautomer_of CHEBI:58045


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L-isoleucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine] CTD PMID:22689575 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19908
    role 19883
      application 19717
        refrigerant 18272
          butane 92
            sec-butyl group 1
              isoleucine 1
                L-isoleucine 1
                  (4S)-3(1),4-dihydroxy-L-isoleucine zwitterion 0
                  Asn-Ile 0
                  Asp-Lys-Ile 0
                  DON-10-isoleucine 0
                  Glu-Asp-Ile 0
                  Glu-Glu-Ile 0
                  Glu-Ile 0
                  Glu-Ile-Phe 0
                  Glu-Ile-Ser 0
                  Glu-Ile-Val 0
                  His-Ile 0
                  Ile-Asp 0
                  Ile-His 0
                  Ile-Ile 0
                  Ile-Leu-Trp-Trp 0
                  Ile-Leu-Val-Tyr 0
                  Ile-Lys 0
                  Ile-Thr 0
                  L-isoleucine derivative + 0
                  L-isoleucine residue + 0
                  L-isoleucino group 0
                  L-isoleucyl group 0
                  Pro-Glu-Ile 0
                  Thr-Ile 0
                  Trp-Ile 0
                  Tyr-Ile-Leu 0
                  alpha-Asp-Ile 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19908
    subatomic particle 19906
      composite particle 19906
        hadron 19906
          baryon 19906
            nucleon 19906
              atomic nucleus 19906
                atom 19906
                  main group element atom 19853
                    p-block element atom 19853
                      carbon group element atom 19799
                        carbon atom 19794
                          organic molecular entity 19794
                            organic group 18960
                              organic divalent group 18941
                                organodiyl group 18941
                                  carbonyl group 18893
                                    carbonyl compound 18893
                                      carboxylic acid 18614
                                        amino acid 15625
                                          alpha-amino acid 13838
                                            L-alpha-amino acid 12820
                                              aspartate family amino acid 3675
                                                L-isoleucine 1
                                                  (4S)-3(1),4-dihydroxy-L-isoleucine zwitterion 0
                                                  Asn-Ile 0
                                                  Asp-Lys-Ile 0
                                                  DON-10-isoleucine 0
                                                  Glu-Asp-Ile 0
                                                  Glu-Glu-Ile 0
                                                  Glu-Ile 0
                                                  Glu-Ile-Phe 0
                                                  Glu-Ile-Ser 0
                                                  Glu-Ile-Val 0
                                                  His-Ile 0
                                                  Ile-Asp 0
                                                  Ile-His 0
                                                  Ile-Ile 0
                                                  Ile-Leu-Trp-Trp 0
                                                  Ile-Leu-Val-Tyr 0
                                                  Ile-Lys 0
                                                  Ile-Thr 0
                                                  L-isoleucine derivative + 0
                                                  L-isoleucine residue + 0
                                                  L-isoleucino group 0
                                                  L-isoleucyl group 0
                                                  Pro-Glu-Ile 0
                                                  Thr-Ile 0
                                                  Trp-Ile 0
                                                  Tyr-Ile-Leu 0
                                                  alpha-Asp-Ile 0
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