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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nucleoside 5'-monophosphate
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Accession:CHEBI:17188 term browser browse the term
Synonyms:related_synonym: Formula=C5H10O7PR;   NMP;   Nucleoside phosphate;   SMILES=O[C@H]1[C@H]([*])O[C@H](COP(O)(O)=O)[C@H]1O;   nucleoside monophosphate;   nucleoside monophosphates
 alt_id: CHEBI:14676;   CHEBI:25607;   CHEBI:7439;   CHEBI:7653;   CHEBI:7654
 xref: KEGG:C01329;   KEGG:C02520
 cyclic_relationship: is_conjugate_acid_of CHEBI:58043


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2'-deoxycytosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Deoxycytidine Monophosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
2'-deoxyguanosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial increases abundance
multiple interactions
EXP IDH2 protein mutant form results in increased abundance of 2'-deoxyguanosine 5'-phosphate
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 2'-deoxyguanosine 5'-phosphate]
CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
3'-CMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) multiple interactions EXP [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate CTD PMID:2579070 NCBI chr 7:126,976,458...126,980,499
Ensembl chr 7:126,975,914...126,980,501
JBrowse link
adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 multiple interactions EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 6:142,587,862...142,702,766
Ensembl chr 6:142,587,862...142,702,315
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions ISO [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr19:20,492,583...20,643,463
Ensembl chr19:20,492,715...20,643,465
JBrowse link
G Ercc6 excision repair cross-complementing rodent repair deficiency, complementation group 6 increases abundance EXP ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr14:32,513,291...32,580,990
Ensembl chr14:32,513,521...32,580,990
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 9:44,334,715...44,336,077
Ensembl chr 9:44,334,694...44,336,077
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions EXP Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 7:46,097,123...46,100,952
Ensembl chr 7:46,093,953...46,100,764
JBrowse link
G Nudt10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:6,168,696...6,173,009
Ensembl chr  X:6,168,696...6,173,015
Ensembl chr  X:6,168,696...6,173,015
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 2:121,194,835...121,296,354
Ensembl chr 2:121,193,281...121,271,407
JBrowse link
G Trp73 transformation related protein 73 affects abundance EXP TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 4:154,056,249...154,139,875
Ensembl chr 4:154,056,253...154,140,208
Ensembl chr 4:154,056,253...154,140,208
JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophospho-N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 6:142,756,686...142,775,714
Ensembl chr 6:142,756,686...142,775,714
JBrowse link
cytidine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) multiple interactions EXP [delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; [Inositol promotes the reaction [CDIPT protein results in increased metabolism of Cytidine Diphosphate Diglycerides]] which results in increased abundance of Cytidine Monophosphate CTD PMID:2579070 NCBI chr 7:126,976,458...126,980,499
Ensembl chr 7:126,975,914...126,980,501
JBrowse link
dTMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Thymidine Monophosphate] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Tyms thymidylate synthase multiple interactions EXP [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate CTD PMID:29258758 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
dUMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 increases export ISO ABCC5 protein results in increased export of 2'-deoxyuridylic acid CTD PMID:15897250 NCBI chr16:20,331,303...20,426,428
Ensembl chr16:20,331,303...20,426,394
JBrowse link
G Tyms thymidylate synthase multiple interactions EXP [Fluorouracil results in decreased activity of TYMS protein] which results in increased abundance of 2'-deoxyuridylic acid CTD PMID:29258758 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
FMN term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial multiple interactions
increases abundance
EXP Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Flavin Mononucleotide] CTD PMID:27469509 NCBI chr 7:80,094,845...80,118,608
Ensembl chr 7:80,094,846...80,115,392
JBrowse link
G Rfk riboflavin kinase increases abundance ISO RFK protein results in increased abundance of Flavin Mononucleotide CTD PMID:21308351 NCBI chr19:17,394,043...17,401,349
Ensembl chr19:17,394,043...17,401,349
JBrowse link
G Slc52a3 solute carrier protein family 52, member 3 multiple interactions ISO Flavin Mononucleotide inhibits the reaction [SLC52A3 protein results in increased transport of Riboflavin] CTD PMID:19122205 NCBI chr 2:151,996,511...152,009,258
Ensembl chr 2:151,996,511...152,009,258
JBrowse link
guanosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fut8 fucosyltransferase 8 decreases activity ISO Guanosine Monophosphate results in decreased activity of FUT8 protein CTD PMID:12770769 NCBI chr12:77,237,430...77,475,998
Ensembl chr12:77,238,125...77,476,338
JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase affects binding ISO Guanosine Monophosphate binds to GMDS protein CTD PMID:25526675 NCBI chr13:31,819,583...32,338,762
Ensembl chr13:31,819,579...32,338,740
JBrowse link
IMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]] CTD PMID:20868668 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [potassium oxonate co-treated with Inosine Monophosphate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]] CTD PMID:20868668 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; SCH 442416 inhibits the reaction [Inosine Monophosphate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]] CTD PMID:20868668 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trp73 transformation related protein 73 affects abundance EXP TP73 protein affects the abundance of Inosine Monophosphate CTD PMID:25554796 NCBI chr 4:154,056,249...154,139,875
Ensembl chr 4:154,056,253...154,140,208
Ensembl chr 4:154,056,253...154,140,208
JBrowse link
poly(cytidylic acid) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) multiple interactions
increases expression
ISO Minocycline inhibits the reaction [Poly C results in increased expression of GRIA1 mRNA] CTD PMID:19660546 NCBI chr11:57,011,571...57,330,244
Ensembl chr11:57,011,387...57,330,244
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) increases expression
multiple interactions
ISO Poly C results in increased expression of GRIN2A mRNA
Minocycline inhibits the reaction [Poly C results in increased expression of GRIN2A mRNA]
CTD PMID:19660546 NCBI chr16:9,567,901...9,996,083
Ensembl chr16:9,567,898...9,995,560
JBrowse link
G Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) multiple interactions
increases expression
ISO Minocycline inhibits the reaction [Poly C results in increased expression of GRIN2C mRNA] CTD PMID:19660546 NCBI chr11:115,249,169...115,267,297
Ensembl chr11:115,249,169...115,267,243
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Poly C results in increased expression of IL1B protein CTD PMID:19660546 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
poly(guanylic acid) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin, alpha 2, smooth muscle, aorta multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of ACTA2 mRNA]; Poly G inhibits the reaction [Particulate Matter results in increased expression of ACTA2 protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein] CTD PMID:30391304 PMID:31028789 NCBI chr19:34,240,336...34,255,585
Ensembl chr19:34,241,090...34,255,590
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ATF6 protein] CTD PMID:31028789 NCBI chr 1:170,704,457...170,868,585
Ensembl chr 1:170,704,674...170,867,771
JBrowse link
G Casp12 caspase 12 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of CASP12 protein] CTD PMID:31028789 NCBI chr 9:5,345,442...5,373,034
Ensembl chr 9:5,345,430...5,373,032
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in decreased expression of CDH1 mRNA]; Poly G inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein]; Poly G inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:30391304 PMID:31028789 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of COL1A1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of COL1A1 mRNA] CTD PMID:30391304 PMID:31028789 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Col3a1 collagen, type III, alpha 1 multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of COL3A1 mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of COL3A1 mRNA] CTD PMID:30391304 PMID:31028789 NCBI chr 1:45,311,538...45,349,706
Ensembl chr 1:45,311,538...45,349,706
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of DDIT3 protein] CTD PMID:31028789 NCBI chr10:127,290,793...127,296,291
Ensembl chr10:127,290,774...127,296,288
Ensembl chr10:127,290,774...127,296,288
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of ERN1 protein] CTD PMID:31028789 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO Poly G inhibits the reaction [Silicon Dioxide results in increased expression of HSPA5 protein] CTD PMID:31028789 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Marco macrophage receptor with collagenous structure multiple interactions EXP
ISO
Poly G inhibits the reaction [MARCO protein binds to and results in increased uptake of Polystyrenes]
Poly G inhibits the reaction [Particulate Matter results in increased expression of MARCO protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of MARCO protein]
CTD PMID:17361018 PMID:30391304 PMID:31028789 NCBI chr 1:120,474,538...120,505,024
Ensembl chr 1:120,474,538...120,505,024
JBrowse link
G Vim vimentin multiple interactions ISO Poly G inhibits the reaction [Particulate Matter results in increased expression of VIM mRNA]; Poly G inhibits the reaction [Particulate Matter results in increased expression of VIM protein]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of VIM mRNA]; Poly G inhibits the reaction [Silicon Dioxide results in increased expression of VIM protein] CTD PMID:30391304 PMID:31028789 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826
JBrowse link
poly(I:C) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700037C18Rik RIKEN cDNA 1700037C18 gene multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RGD1561796 mRNA CTD PMID:26923065 NCBI chr16:3,905,798...3,908,689
Ensembl chr16:3,895,179...3,908,689
JBrowse link
G 4932438A13Rik RIKEN cDNA 4932438A13 gene multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RGD1307100 mRNA CTD PMID:26923065 NCBI chr 3:36,863,063...37,053,033
Ensembl chr 3:36,863,104...37,053,033
JBrowse link
G Abhd2 abhydrolase domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ABHD2 mRNA CTD PMID:26923065 NCBI chr 7:79,273,266...79,361,601
Ensembl chr 7:79,273,199...79,365,508
JBrowse link
G Ablim1 actin-binding LIM protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ABLIM1 mRNA CTD PMID:26923065 NCBI chr19:57,032,733...57,315,344
Ensembl chr19:57,032,733...57,314,919
JBrowse link
G Acads acyl-Coenzyme A dehydrogenase, short chain multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ACADS mRNA CTD PMID:26923065 NCBI chr 5:115,110,299...115,119,346
Ensembl chr 5:115,110,299...115,119,346
JBrowse link
G Adam10 a disintegrin and metallopeptidase domain 10 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ADAM10 mRNA CTD PMID:26923065 NCBI chr 9:70,678,944...70,780,229
Ensembl chr 9:70,678,997...70,780,229
JBrowse link
G Ahcyl1 S-adenosylhomocysteine hydrolase-like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of AHCYL1 mRNA CTD PMID:26923065 NCBI chr 3:107,663,120...107,696,560
Ensembl chr 3:107,663,118...107,696,560
JBrowse link
G Ahr aryl-hydrocarbon receptor increases expression ISO Poly I-C results in increased expression of AHR mRNA; Poly I-C results in increased expression of AHR protein CTD PMID:27783115 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Akap5 A kinase (PRKA) anchor protein 5 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of AKAP5 mRNA CTD PMID:26923065 NCBI chr12:76,324,617...76,334,517
Ensembl chr12:76,324,891...76,334,153
JBrowse link
G App amyloid beta (A4) precursor protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of APP mRNA CTD PMID:26923065 NCBI chr16:84,952,666...85,175,255
Ensembl chr16:84,949,685...85,173,766
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 increases degradation
multiple interactions
EXP Poly I-C results in increased degradation of APPL1 protein
APPL1 protein inhibits the reaction [Poly I-C results in increased expression of IL1B protein]; APPL1 protein inhibits the reaction [Poly I-C results in increased expression of TNF protein]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; APPL1 protein promotes the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IKBKE protein]; APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; trametinib inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; U 0126 inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]
CTD PMID:25780039 NCBI chr14:26,918,986...26,970,611
Ensembl chr14:26,918,988...26,971,232
JBrowse link
G Arc activity regulated cytoskeletal-associated protein affects methylation ISO Poly I-C affects the methylation of ARC promoter CTD PMID:32843831 NCBI chr15:74,669,081...74,672,570
Ensembl chr15:74,669,083...74,672,570
JBrowse link
G Arfgef3 ARFGEF family member 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARFGEF3 mRNA CTD PMID:26923065 NCBI chr10:18,588,011...18,743,758
Ensembl chr10:18,581,839...18,743,949
JBrowse link
G Arg2 arginase type II multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ARG2 mRNA CTD PMID:26923065 NCBI chr12:79,130,788...79,156,301
Ensembl chr12:79,130,777...79,156,301
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ARHGAP11A mRNA CTD PMID:26923065 NCBI chr 2:113,831,492...113,848,661
Ensembl chr 2:113,831,492...113,848,661
JBrowse link
G Arhgap44 Rho GTPase activating protein 44 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARHGAP44 mRNA CTD PMID:26923065 NCBI chr11:65,002,039...65,162,972
Ensembl chr11:65,002,039...65,162,961
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ARHGAP9 mRNA CTD PMID:26923065 NCBI chr10:127,321,913...127,329,947
Ensembl chr10:127,321,964...127,329,943
JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARHGEF12 mRNA CTD PMID:26923065 NCBI chr 9:42,963,842...43,105,718
Ensembl chr 9:42,963,842...43,107,239
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor (GEF7) multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARHGEF7 mRNA CTD PMID:26923065 NCBI chr 8:11,728,001...11,835,219
Ensembl chr 8:11,727,721...11,835,219
JBrowse link
G Arsb arylsulfatase B multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ARSB mRNA CTD PMID:26923065 NCBI chr13:93,771,679...93,943,016
Ensembl chr13:93,771,630...93,943,016
JBrowse link
G Art3 ADP-ribosyltransferase 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of ART3 mRNA CTD PMID:26923065 NCBI chr 5:92,331,799...92,414,628
Ensembl chr 5:92,331,827...92,414,628
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Poly I-C results in increased expression of ATF3 mRNA CTD PMID:27783115 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ATP2B2 mRNA CTD PMID:26923065 NCBI chr 6:113,743,831...114,042,613
Ensembl chr 6:113,743,831...114,042,613
JBrowse link
G Atxn3 ataxin 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ATXN3 mRNA CTD PMID:26923065 NCBI chr12:101,918,901...101,959,121
Ensembl chr12:101,918,901...101,958,246
JBrowse link
G AW549877 expressed sequence AW549877 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RGD1305938 mRNA CTD PMID:26923065 NCBI chr15:3,982,035...3,995,746
Ensembl chr15:3,982,035...3,995,744
JBrowse link
G Bax BCL2-associated X protein increases expression ISO Poly I-C results in increased expression of BAX protein CTD PMID:21418039 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO Poly I-C results in decreased expression of BCL2 protein CTD PMID:21418039 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of BCL2A1 mRNA CTD PMID:26923065 NCBI chr 9:89,199,273...89,207,838
Ensembl chr 9:89,199,209...89,207,827
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
affects methylation
EXP
ISO
[Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of BDNF mRNA; Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of BDNF mRNA]
Poly I-C affects the methylation of BDNF promoter
CTD PMID:24889602 PMID:32843831 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO Poly I-C results in decreased expression of BID protein CTD PMID:21418039 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO Poly I-C promotes the reaction [arsenic trioxide results in decreased expression of BIRC5 protein] CTD PMID:21418039 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of BIRC6 mRNA CTD PMID:26923065 NCBI chr17:74,528,254...74,703,356
Ensembl chr17:74,528,295...74,703,356
JBrowse link
G Blmh bleomycin hydrolase multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of BLMH mRNA CTD PMID:26923065 NCBI chr11:76,945,656...76,987,389
Ensembl chr11:76,924,809...76,987,379
JBrowse link
G Brox BRO1 domain and CAAX motif containing multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of BROX mRNA CTD PMID:26923065 NCBI chr 1:183,276,352...183,297,298
Ensembl chr 1:183,276,352...183,297,269
JBrowse link
G C1qtnf7 C1q and tumor necrosis factor related protein 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of C1QTNF7 mRNA CTD PMID:26923065 NCBI chr 5:43,515,425...43,619,126
Ensembl chr 5:43,515,538...43,618,803
JBrowse link
G Cage1 cancer antigen 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CAGE1 mRNA CTD PMID:26923065 NCBI chr13:38,006,052...38,037,131
Ensembl chr13:38,006,052...38,037,069
JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CA3 mRNA CTD PMID:26923065 NCBI chr 3:14,863,538...14,872,381
Ensembl chr 3:14,863,512...14,872,523
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein]]; arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]; Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein] CTD PMID:21418039 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP8 protein]; Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP8 protein] CTD PMID:21418039 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein]]; arsenic trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]; Poly I-C promotes the reaction [arsenic trioxide results in increased activity of CASP9 protein] CTD PMID:21418039 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cat catalase decreases expression ISO Poly I-C results in decreased expression of CAT mRNA CTD PMID:23939143 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cav1 caveolin 1, caveolae protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CAV1 mRNA CTD PMID:26923065 NCBI chr 6:17,306,335...17,341,328
Ensembl chr 6:17,306,335...17,341,452
JBrowse link
G Cbx1 chromobox 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CBX1 mRNA CTD PMID:26923065 NCBI chr11:96,788,680...96,808,982
Ensembl chr11:96,789,127...96,808,640
JBrowse link
G Cbx6 chromobox 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CBX6 mRNA CTD PMID:26923065 NCBI chr15:79,823,898...79,834,333
Ensembl chr15:79,823,896...79,834,688
JBrowse link
G Ccdc113 coiled-coil domain containing 113 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CCDC113 mRNA CTD PMID:26923065 NCBI chr 8:95,534,060...95,558,888
Ensembl chr 8:95,534,085...95,558,890
JBrowse link
G Ccl1 chemokine (C-C motif) ligand 1 increases expression ISO Poly I-C results in increased expression of CCL1 mRNA CTD PMID:27783115 NCBI chr11:82,176,666...82,179,812
Ensembl chr11:82,176,657...82,305,690
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 multiple interactions
increases secretion
EXP methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL11 protein] CTD PMID:24056979 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions
increases expression
increases secretion
EXP
ISO
methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL2 protein]
Poly I-C results in increased expression of CCL2 mRNA
CTD PMID:23939143 PMID:24056979 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 multiple interactions
increases expression
EXP Ethanol inhibits the reaction [Poly I-C results in increased expression of CCL3 protein] CTD PMID:19500611 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 multiple interactions
increases expression
increases secretion
EXP
ISO
Ethanol inhibits the reaction [Poly I-C results in increased expression of CCL4 protein]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL4 protein]
6-formylindolo(3,2-b)carbazole inhibits the reaction [Poly I-C results in increased expression of CCL4 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Poly I-C results in increased expression of CCL4 mRNA]
CTD PMID:19500611 PMID:24056979 PMID:27783115 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions
increases expression
increases secretion
EXP
ISO
APPL1 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CCL5 protein]; trametinib promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]
Poly I-C results in increased expression of CCL5; Poly I-C results in increased expression of CCL5 mRNA
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; [Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Particulate Matter inhibits the reaction [Poly I-C results in increased expression of CCL5]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of CCL5]
CTD PMID:23688403 PMID:24056979 PMID:24709138 PMID:25780039 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cd40 CD40 antigen increases expression
multiple interactions
ISO Poly I-C results in increased expression of CD40 protein
[Poly I-C co-treated with IFNG protein] results in increased secretion of CD40 protein
CTD PMID:15246609 PMID:16224278 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Cd80 CD80 antigen increases expression ISO Poly I-C results in increased expression of CD80 protein CTD PMID:15246609 NCBI chr16:38,457,430...38,495,958
Ensembl chr16:38,455,561...38,496,335
JBrowse link
G Cd83 CD83 antigen increases expression
multiple interactions
ISO Poly I-C results in increased expression of CD83 protein
CEP-11004 inhibits the reaction [Poly I-C results in increased expression of CD83 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased expression of CD83 protein]
CTD PMID:17698565 NCBI chr13:43,785,112...43,803,133
Ensembl chr13:43,784,775...43,803,132
JBrowse link
G Cd86 CD86 antigen multiple interactions
increases expression
ISO [Poly I-C co-treated with IFNG protein] results in increased secretion of CD86 protein; CEP-11004 inhibits the reaction [Poly I-C results in increased expression of CD86 protein]; Particulate Matter analog inhibits the reaction [Poly I-C results in increased expression of CD86 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased expression of CD86 protein]; Vehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of CD86 protein] CTD PMID:15246609 PMID:16224278 PMID:16890772 PMID:17698565 NCBI chr16:36,568,956...36,666,158
Ensembl chr16:36,603,869...36,666,081
JBrowse link
G Cdx2 caudal type homeobox 2 multiple interactions ISO [Poly I-C co-treated with 6-formylindolo(3,2-b)carbazole] results in increased expression of CDX2 mRNA; [Poly I-C co-treated with Tetrachlorodibenzodioxin] results in increased expression of CDX2 mRNA CTD PMID:27783115 NCBI chr 5:147,300,900...147,307,249
Ensembl chr 5:147,300,805...147,307,270
JBrowse link
G Celf1 CUGBP, Elav-like family member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CELF1 mRNA CTD PMID:26923065 NCBI chr 2:90,940,259...91,019,497
Ensembl chr 2:90,940,382...91,019,497
JBrowse link
G Cfp complement factor properdin multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CFP mRNA CTD PMID:26923065 NCBI chr  X:20,925,454...20,931,555
Ensembl chr  X:20,925,454...20,931,555
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CHSY1 mRNA CTD PMID:26923065 NCBI chr 7:66,109,492...66,173,798
Ensembl chr 7:66,109,515...66,173,798
JBrowse link
G Cibar2 CBY1 interacting BAR domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CIBAR2 mRNA CTD PMID:26923065 NCBI chr 8:120,166,397...120,177,486
Ensembl chr 8:120,166,397...120,177,466
JBrowse link
G Clcc1 chloride channel CLIC-like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CLCC1 mRNA CTD PMID:26923065 NCBI chr 3:108,653,878...108,678,840
Ensembl chr 3:108,653,913...108,678,840
JBrowse link
G Clec14a C-type lectin domain family 14, member a multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CLEC14A mRNA CTD PMID:26923065 NCBI chr12:58,264,720...58,269,258
Ensembl chr12:58,264,720...58,269,290
JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CLIP3 mRNA CTD PMID:26923065 NCBI chr 7:30,291,695...30,308,367
Ensembl chr 7:30,291,728...30,308,367
JBrowse link
G Cnnm1 cyclin M1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CNNM1 mRNA CTD PMID:26923065 NCBI chr19:43,439,069...43,497,210
Ensembl chr19:43,440,436...43,497,210
JBrowse link
G Cnr1 cannabinoid receptor 1 (brain) multiple interactions ISO Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein] CTD PMID:31202911 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 (macrophage) increases expression ISO Poly I-C results in increased expression of CNR2 mRNA CTD PMID:27317300 NCBI chr 4:135,895,189...135,920,219
Ensembl chr 4:135,895,394...135,920,207
JBrowse link
G Cntn1 contactin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CNTN1 mRNA CTD PMID:26923065 NCBI chr15:92,051,152...92,341,967
Ensembl chr15:92,051,165...92,341,967
JBrowse link
G Crabp1 cellular retinoic acid binding protein I multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CRABP1 mRNA CTD PMID:26923065 NCBI chr 9:54,764,748...54,773,110
Ensembl chr 9:54,764,748...54,773,110
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions
increases expression
EXP Ethanol inhibits the reaction [Poly I-C results in increased expression of CSF2 protein] CTD PMID:19500611 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Cttnbp2 cortactin binding protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CTTNBP2 mRNA CTD PMID:26923065 NCBI chr 6:18,366,471...18,515,217
Ensembl chr 6:18,366,478...18,514,843
JBrowse link
G Cxcl1 chemokine (C-X-C motif) ligand 1 increases expression ISO Poly I-C results in increased expression of CXCL1 mRNA CTD PMID:23939143 NCBI chr 5:90,891,245...90,893,121
Ensembl chr 5:90,891,241...90,893,115
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 multiple interactions
increases expression
EXP
ISO
APPL1 protein promotes the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; chrysin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; eriodictyol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Luteolin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Quercetin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; trametinib promotes the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; [Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein; bafilomycin A1 inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Dronabinol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Dronabinol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Particulate Matter inhibits the reaction [[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein]; Phosphorothioate Oligonucleotides inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Smoke inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Vehicle Emissions inhibits the reaction [[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with Imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein]
Poly I-C results in increased expression of CXCL10 mRNA; Poly I-C results in increased expression of CXCL10 protein
CTD PMID:19426678 PMID:25780039 PMID:26682054 PMID:28003376 PMID:28572013 PMID:28655636 PMID:28726298 PMID:32244040 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions
increases expression
increases secretion
ISO 1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Estradiol promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]; [Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; CpG ODN 2006 inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of CXCL8 protein]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Particulate Matter promotes the reaction [Poly I-C results in increased expression of CXCL8]; Poly I-C affects the reaction [Gold Sodium Thiosulfate results in increased secretion of CXCL8 protein]; pyrazolanthrone inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; RTKI cpd inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of CXCL8 protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; Vehicle Emissions promotes the reaction [Poly I-C results in increased expression of CXCL8]; Vehicle Emissions promotes the reaction [Poly I-C results in increased secretion of CXCL8 protein]
Poly I-C results in increased expression of CXCL8; Poly I-C results in increased expression of CXCL8 mRNA; Poly I-C results in increased expression of CXCL8 protein
CTD PMID:17669408 PMID:18779317 PMID:20932985 PMID:23618096 PMID:23688403 PMID:24709138 PMID:25458486 PMID:26160521 PMID:26456670 PMID:30017638 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 increases expression ISO Poly I-C results in increased expression of CXCL2 mRNA CTD PMID:23939143 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Cxcl3 chemokine (C-X-C motif) ligand 3 multiple interactions
increases expression
EXP Ethanol inhibits the reaction [Poly I-C results in increased expression of CXCL1 protein] CTD PMID:19500611 NCBI chr 5:90,786,101...90,788,093
Ensembl chr 5:90,786,103...90,789,600
JBrowse link
G Cxcl9 chemokine (C-X-C motif) ligand 9 multiple interactions
increases secretion
increases expression
EXP Luteolin inhibits the reaction [Poly I-C results in increased expression of CXCL9 mRNA]; methyldithiocarbamate inhibits the reaction [Poly I-C results in increased secretion of CXCL9 protein] CTD PMID:19426678 PMID:24056979 NCBI chr 5:92,321,331...92,328,079
Ensembl chr 5:92,321,347...92,328,079
JBrowse link
G Cyfip2 cytoplasmic FMR1 interacting protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CYFIP2 mRNA CTD PMID:26923065 NCBI chr11:46,193,849...46,312,859
Ensembl chr11:46,193,850...46,312,859
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Poly I-C promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA] CTD PMID:27783115 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases expression ISO Poly I-C results in decreased expression of CYP2C6V1 mRNA CTD PMID:23939143 NCBI chr19:39,389,556...39,463,103
Ensembl chr19:39,389,556...39,463,075
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene decreases expression ISO Poly I-C results in decreased expression of CYP2C11 mRNA CTD PMID:23939143 NCBI chr19:38,976,662...39,003,627
Ensembl chr19:38,976,647...39,003,289
JBrowse link
G Cyria CYFIP related Rac1 interactor A multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of CYRIA mRNA CTD PMID:26923065 NCBI chr12:12,262,134...12,380,965
Ensembl chr12:12,262,139...12,380,965
JBrowse link
G Cysrt1 cysteine rich tail 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of CYSRT1 mRNA CTD PMID:26923065 NCBI chr 2:25,238,819...25,239,897
Ensembl chr 2:25,238,818...25,242,452
JBrowse link
G Dab1 disabled 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DAB1 mRNA CTD PMID:26923065 NCBI chr 4:103,619,500...104,744,844
Ensembl chr 4:103,619,359...104,744,844
JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DCK mRNA CTD PMID:26923065 NCBI chr 5:88,765,013...88,783,277
Ensembl chr 5:88,764,996...88,783,281
JBrowse link
G Dcun1d3 DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DCUN1D3 mRNA CTD PMID:26923065 NCBI chr 7:119,853,158...119,896,330
Ensembl chr 7:119,852,796...119,896,298
JBrowse link
G Dcun1d4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae) multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DCUN1D4 mRNA CTD PMID:26923065 NCBI chr 5:73,481,010...73,560,794
Ensembl chr 5:73,481,000...73,560,794
JBrowse link
G Ddx3x DEAD box helicase 3, X-linked multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DDX3X mRNA CTD PMID:26923065 NCBI chr  X:13,280,496...13,293,988
Ensembl chr  X:13,280,970...13,294,052
JBrowse link
G Ddx58 DEAD/H box helicase 58 increases expression
multiple interactions
ISO Poly I-C results in increased expression of DDX58 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of DDX58 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of DDX58 mRNA]
CTD PMID:27183587 PMID:30341573 PMID:31154625 NCBI chr 4:40,203,777...40,239,825
Ensembl chr 4:40,203,773...40,239,828
JBrowse link
G Defb4 defensin beta 4 increases secretion ISO Poly I-C results in increased secretion of DEFB4 protein CTD PMID:17669408 NCBI chr 8:19,198,704...19,201,547
Ensembl chr 8:19,198,706...19,201,545
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of DLG1 mRNA CTD PMID:26923065 NCBI chr16:31,663,443...31,873,356
Ensembl chr16:31,663,443...31,875,129
JBrowse link
G Dnm2 dynamin 2 multiple interactions EXP DNM2 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein] CTD PMID:25780039 NCBI chr 9:21,424,908...21,507,759
Ensembl chr 9:21,424,908...21,507,759
JBrowse link
G Eea1 early endosome antigen 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of EEA1 mRNA CTD PMID:26923065 NCBI chr10:95,940,663...96,045,518
Ensembl chr10:95,940,650...96,045,518
JBrowse link
G Egr1 early growth response 1 multiple interactions
affects methylation
EXP
ISO
[Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of EGR1 mRNA; Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of EGR1 mRNA]
Poly I-C affects the methylation of EGR1 promoter
CTD PMID:24889602 PMID:32843831 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 increases expression
increases response to substance
ISO
EXP
Poly I-C results in increased expression of EIF2AK2 mRNA
EIF2AK2 results in increased susceptibility to Poly I-C
CTD PMID:10944112 PMID:17669408 PMID:22558189 NCBI chr17:78,850,504...78,882,572
Ensembl chr17:78,852,564...78,882,573
JBrowse link
G F11r F11 receptor multiple interactions
decreases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; CpG ODN 2006 inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; RTKI cpd inhibits the reaction [Poly I-C results in decreased expression of F11R protein]; SB 203580 inhibits the reaction [Poly I-C results in decreased expression of F11R protein] CTD PMID:20932985 NCBI chr 1:171,437,561...171,464,593
Ensembl chr 1:171,437,535...171,464,603
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte increases expression EXP Poly I-C results in increased expression of FABP4 mRNA CTD PMID:15705927 NCBI chr 3:10,204,342...10,208,616
Ensembl chr 3:10,204,088...10,208,576
JBrowse link
G Fam107a family with sequence similarity 107, member A multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of FAM107A mRNA CTD PMID:26923065 NCBI chr14:8,296,270...8,317,607
Ensembl chr14:8,296,274...8,318,023
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions
decreases expression
EXP Suramin inhibits the reaction [Poly I-C results in decreased expression of FMR1 protein] CTD PMID:23516405 NCBI chr  X:68,678,536...68,717,963
Ensembl chr  X:68,678,541...68,717,963
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of FXYD3 mRNA CTD PMID:26923065 NCBI chr 7:31,070,535...31,076,697
Ensembl chr 7:31,068,172...31,076,704
JBrowse link
G Fyttd1 forty-two-three domain containing 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of FYTTD1 mRNA CTD PMID:26923065 NCBI chr16:32,877,581...32,908,963
Ensembl chr16:32,877,500...32,908,875
JBrowse link
G G3bp2 GTPase activating protein (SH3 domain) binding protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of G3BP2 mRNA CTD PMID:26923065 NCBI chr 5:92,052,145...92,137,725
Ensembl chr 5:92,052,146...92,083,719
JBrowse link
G Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GABRA1 mRNA CTD PMID:26923065 NCBI chr11:42,130,939...42,183,066
Ensembl chr11:42,130,939...42,182,930
JBrowse link
G Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GABRB2 mRNA CTD PMID:26923065 NCBI chr11:42,419,515...42,632,591
Ensembl chr11:42,419,757...42,629,028
JBrowse link
G Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GABRG2 mRNA CTD PMID:26923065 NCBI chr11:41,910,190...42,000,857
Ensembl chr11:41,910,203...42,000,857
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
decreases expression
ISO Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 NCBI chr 2:70,561,303...70,602,014
Ensembl chr 2:70,553,072...70,602,014
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GDAP1 mRNA CTD PMID:26923065 NCBI chr 1:17,145,373...17,164,271
Ensembl chr 1:17,145,362...17,164,271
JBrowse link
G Gdi1 guanosine diphosphate (GDP) dissociation inhibitor 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GDI1 mRNA CTD PMID:26923065 NCBI chr  X:74,305,012...74,311,867
Ensembl chr  X:74,304,998...74,311,862
JBrowse link
G Get3 guided entry of tail-anchored proteins factor 3, ATPase multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of GET3 mRNA CTD PMID:26923065 NCBI chr 8:85,017,929...85,025,287
Ensembl chr 8:85,017,931...85,025,281
JBrowse link
G Gfap glial fibrillary acidic protein increases expression ISO Poly I-C results in increased expression of GFAP mRNA CTD PMID:27317300 NCBI chr11:102,887,336...102,897,200
Ensembl chr11:102,887,336...102,900,912
JBrowse link
G Gh growth hormone decreases expression EXP Poly I-C results in decreased expression of GH protein CTD PMID:21195166 NCBI chr11:106,300,261...106,303,703
Ensembl chr11:106,300,271...106,301,865
JBrowse link
G Glce glucuronyl C5-epimerase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GLCE mRNA CTD PMID:26923065 NCBI chr 9:62,057,244...62,122,609
Ensembl chr 9:62,057,248...62,122,655
JBrowse link
G Glrb glycine receptor, beta subunit multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GLRB mRNA CTD PMID:26923065 NCBI chr 3:80,843,598...80,913,660
Ensembl chr 3:80,843,599...80,913,660
JBrowse link
G Glyr1 glyoxylate reductase 1 homolog (Arabidopsis) multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GLYR1 mRNA CTD PMID:26923065 NCBI chr16:5,013,902...5,049,938
Ensembl chr16:5,013,909...5,049,863
JBrowse link
G Gmfb glia maturation factor, beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GMFB mRNA CTD PMID:26923065 NCBI chr14:46,808,149...46,822,259
Ensembl chr14:46,808,149...46,822,242
JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of GMPPB mRNA CTD PMID:26923065 NCBI chr 9:108,049,239...108,051,923
Ensembl chr 9:108,049,242...108,052,801
JBrowse link
G Gpatch2l G patch domain containing 2 like multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GPATCH2L mRNA CTD PMID:26923065 NCBI chr12:86,241,795...86,294,657
Ensembl chr12:86,241,858...86,291,784
JBrowse link
G Gpbp1 GC-rich promoter binding protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of GPBP1 mRNA CTD PMID:26923065 NCBI chr13:111,425,680...111,490,128
Ensembl chr13:111,425,680...111,490,111
JBrowse link
G Gsr glutathione reductase decreases expression ISO Poly I-C results in decreased expression of GSR mRNA CTD PMID:23939143 NCBI chr 8:33,653,238...33,698,162
Ensembl chr 8:33,652,523...33,698,163
JBrowse link
G Gzmb granzyme B multiple interactions
increases expression
ISO Particulate Matter inhibits the reaction [Poly I-C results in increased expression of GZMB mRNA]; Particulate Matter inhibits the reaction [Poly I-C results in increased expression of GZMB protein]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of GZMB mRNA]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of GZMB protein]
Poly I-C results in increased expression of GZMB mRNA; Poly I-C results in increased expression of GZMB protein
CTD PMID:23618096 NCBI chr14:56,258,836...56,262,334
Ensembl chr14:56,258,838...56,262,260
JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of HEY2 mRNA CTD PMID:26923065 NCBI chr10:30,832,359...30,842,783
Ensembl chr10:30,832,359...30,842,801
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO Diclofenac promotes the reaction [Poly I-C results in increased expression of HMOX1 mRNA] CTD PMID:23939143 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 increases expression ISO Poly I-C results in increased expression of HSP90AA1 mRNA CTD PMID:23939143 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO Poly I-C results in increased expression of HSPA1A mRNA CTD PMID:23939143 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa8 heat shock protein 8 increases expression ISO Poly I-C results in increased expression of HSPA8 mRNA CTD PMID:23939143 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A increases expression EXP Poly I-C results in increased expression of HTR2A mRNA CTD PMID:24889602 NCBI chr14:74,640,874...74,706,859
Ensembl chr14:74,640,840...74,709,494
JBrowse link
G Ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of IBTK mRNA CTD PMID:26923065 NCBI chr 9:85,687,359...85,750,703
Ensembl chr 9:85,687,360...85,749,334
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression
multiple interactions
ISO Poly I-C results in increased expression of IDO1 mRNA
poly(I:C) co-treated with tryptophan or alone increases activity and expression of IDO1 protein in Langerhans cell-like dendritic cells
CTD PMID:27783115, PMID:26198597 RGD:11528429 NCBI chr 8:24,584,133...24,596,952
Ensembl chr 8:24,584,136...24,597,009
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 increases expression ISO Poly I-C results in increased expression of IDO2 mRNA CTD PMID:27783115 NCBI chr 8:24,531,892...24,576,414
Ensembl chr 8:24,531,892...24,576,333
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 multiple interactions
increases expression
ISO IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIH1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IFIH1 mRNA] CTD PMID:30341573 PMID:31154625 NCBI chr 2:62,595,618...62,646,255
Ensembl chr 2:62,595,798...62,646,255
JBrowse link
G Ifnb1 interferon beta 1, fibroblast increases expression
increases secretion
multiple interactions
ISO
EXP
Poly I-C results in increased expression of IFNB1 mRNA; Poly I-C results in increased expression of IFNB1 protein
Poly I-C results in increased secretion of IFNB1 protein
MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
APPL1 protein promotes the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; BX795 inhibits the reaction [Poly I-C results in increased expression of IFNB1 protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Progesterone inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Resveratrol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; trametinib promotes the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; [Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of IFNB1 mRNA; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Dronabinol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; IRF7 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; IRF7 protein mutant form affects the reaction [Nicotine inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]]; IRF7 protein mutant form inhibits the reaction [Nicotine inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Smoke inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Wortmannin inhibits the reaction [[Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of IFNB1 mRNA]
CTD PMID:16116226 PMID:16399790 PMID:17669408 PMID:18279804 PMID:18323514 PMID:18779317 PMID:19426678 PMID:21418039 PMID:22546503 PMID:22558189 PMID:24423102 PMID:25780039 PMID:28572013 PMID:28726298 PMID:30726814 PMID:31154625 PMID:32244040 NCBI chr 4:88,522,025...88,522,794
Ensembl chr 4:88,522,025...88,522,774
JBrowse link
G Ifng interferon gamma multiple interactions
increases secretion
increases expression
ISO
EXP
[Poly I-C co-treated with IFNG protein] results in increased secretion of CD40 protein; [Poly I-C co-treated with IFNG protein] results in increased secretion of CD86 protein; Smoke inhibits the reaction [Poly I-C results in increased expression of IFNG mRNA]
Poly I-C results in increased secretion of IFNG protein
Poly I-C results in increased expression of IFNG mRNA; Poly I-C results in increased expression of IFNG protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of IFNG protein]
CTD PMID:9328138 PMID:16224278 PMID:17321468 PMID:19500611 PMID:23618096 PMID:23939143 PMID:28572013 PMID:30836164 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
EXP IL6 protein affects the reaction [Poly I-C results in decreased expression of IGF1 protein]
Poly I-C results in decreased expression of IGF1 mRNA; Poly I-C results in decreased expression of IGF1 protein
CTD PMID:1705203 PMID:21195166 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
decreases expression
EXP IL6 protein affects the reaction [Poly I-C results in decreased expression of IGFBP3 protein] CTD PMID:21195166 NCBI chr11:7,206,086...7,215,498
Ensembl chr11:7,206,086...7,213,923
JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of IGSF6 mRNA CTD PMID:26923065 NCBI chr 7:121,064,067...121,074,581
Ensembl chr 7:121,064,067...121,074,572
JBrowse link
G Ikbke inhibitor of kappaB kinase epsilon multiple interactions
increases phosphorylation
EXP APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IKBKE protein] CTD PMID:25780039 NCBI chr 1:131,254,600...131,279,601
Ensembl chr 1:131,254,343...131,279,606
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
increases secretion
ISO
EXP
CEP-11004 inhibits the reaction [Poly I-C results in increased secretion of IL10 protein]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of IL10 protein]
Poly I-C results in increased expression of IL10 mRNA
Poly I-C results in increased expression of IL10 mRNA; Poly I-C results in increased expression of IL10 protein
Citrinin inhibits the reaction [Poly I-C results in increased expression of IL10 mRNA]; Citrinin inhibits the reaction [Poly I-C results in increased expression of IL10 protein]
CTD PMID:16224278 PMID:17698565 PMID:22771370 PMID:23618096 PMID:23939143 PMID:30836164 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il12a interleukin 12a multiple interactions
increases expression
ISO 6-formylindolo(3,2-b)carbazole inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA]; indole-3-carbinol inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Poly I-C results in increased expression of IL12A mRNA] CTD PMID:27783115 NCBI chr 3:68,690,644...68,698,550
Ensembl chr 3:68,690,644...68,698,547
JBrowse link
G Il12b interleukin 12b multiple interactions
increases expression
ISO
EXP
[[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein; Particulate Matter analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]; Vehicle Emissions analog inhibits the reaction [Poly I-C results in increased expression of IL12B protein]
Poly I-C results in increased expression of IL12B mRNA; Poly I-C results in increased expression of IL12B protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of IL12B protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IL12B mRNA]
CTD PMID:16890772 PMID:19426678 PMID:19500611 PMID:23266719 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il17a interleukin 17A increases expression EXP Poly I-C results in increased expression of IL17A protein CTD PMID:30836164 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
increases expression
EXP
ISO
APPL1 protein inhibits the reaction [Poly I-C results in increased expression of IL1B protein]; Citrinin inhibits the reaction [Poly I-C results in increased expression of IL1B mRNA]; Ethanol inhibits the reaction [Poly I-C results in increased expression of IL1B protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]
Poly I-C results in increased secretion of IL1B protein
Poly I-C results in increased expression of IL1B mRNA; Poly I-C results in increased expression of IL1B protein
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of IL1B protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of IL1B protein]; 6-formylindolo(3,2-b)carbazole promotes the reaction [Poly I-C results in increased expression of IL1B mRNA]; Estradiol promotes the reaction [Poly I-C results in increased expression of IL1B protein]; Tetrachlorodibenzodioxin promotes the reaction [Poly I-C results in increased expression of IL1B mRNA]
CTD PMID:16687389 PMID:17321468 PMID:19500611 PMID:22771370 PMID:23618096 PMID:23939143 PMID:25780039 PMID:27783115 PMID:28316773 PMID:30017638 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il2 interleukin 2 increases expression
increases secretion
EXP
ISO
Poly I-C results in increased expression of IL2 mRNA
Poly I-C results in increased secretion of IL2 protein
CTD PMID:9328138 PMID:23618096 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il27 interleukin 27 increases expression
multiple interactions
EXP Poly I-C results in increased expression of IL27 mRNA
Luteolin inhibits the reaction [Poly I-C results in increased expression of IL27 mRNA]
CTD PMID:19426678 NCBI chr 7:126,589,009...126,595,035
Ensembl chr 7:126,589,010...126,594,941
JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression
ISO
EXP
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of IL33 protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of IL33 protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of IL33 protein]
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Poly I-C results in increased expression of IL33 protein]
CTD PMID:25747661 PMID:30017638 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
G Il4 interleukin 4 multiple interactions
increases expression
increases secretion
increases response to substance
ISO
EXP
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of IL4 protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; [Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2; [Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2; [Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein; [Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein; [Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprost; [Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone; [Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; amorolfine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; butenafine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Estradiol promotes the reaction [Poly I-C results in increased expression of IL4 protein]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CCL5 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Itraconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Ketoconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; luliconazole promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Particulate Matter inhibits the reaction [Poly I-C results in increased secretion of IL4 protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of 15-deoxy-delta(12,14)-prostaglandin J2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in decreased secretion of Prostaglandin D2]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CCL5 mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of CXCL8 mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Thromboxane B2]; Terbinafine promotes the reaction [[Poly I-C co-treated with IL4 protein] results in increased secretion of Dinoprostone]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased secretion of IL4 protein]
IL4 protein results in increased susceptibility to Poly I-C
CTD PMID:23618096 PMID:23688403 PMID:30017638 PMID:30836164 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
ISO
EXP
[Vehicle Emissions analog co-treated with Poly I-C] results in increased secretion of IL6 protein; CEP-11004 inhibits the reaction [Poly I-C results in increased secretion of IL6 protein]; Particulate Matter promotes the reaction [Poly I-C results in increased expression of IL6]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of IL6 protein]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]; TRAF6 mutant form inhibits the reaction [Vehicle Emissions analog promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]]; Vehicle Emissions analog promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]; Vehicle Emissions promotes the reaction [Poly I-C results in increased expression of IL6]
Poly I-C results in increased expression of IL6 mRNA; Poly I-C results in increased expression of IL6 protein
Ethanol inhibits the reaction [Poly I-C results in increased expression of IL6 protein]; IL6 protein affects the reaction [Poly I-C results in decreased expression of IGF1 protein]; IL6 protein affects the reaction [Poly I-C results in decreased expression of IGFBP3 protein]; IL6 protein affects the reaction [Poly I-C results in increased expression of PRL2B1 mRNA]; IL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein]; Luteolin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; pitavastatin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of IL6 mRNA]
Poly I-C results in increased expression of IL6; Poly I-C results in increased expression of IL6 mRNA
CTD PMID:9328138 PMID:16399790 PMID:16687389 PMID:17698565 PMID:18323514 PMID:19426678 PMID:19500611 PMID:21195166 PMID:23939143 PMID:24709138 PMID:26160521 PMID:28316773 PMID:30341573 PMID:30726814 PMID:30836164 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Irf3 interferon regulatory factor 3 increases phosphorylation
affects localization
multiple interactions
ISO
EXP
Poly I-C results in increased phosphorylation of IRF3 protein
Poly I-C affects the localization of IRF3 protein
APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; BX795 inhibits the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; Chloroquine inhibits the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; chrysin inhibits the reaction [Poly I-C results in increased expression of IRF3 mRNA]; DNM2 protein promotes the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; eriodictyol inhibits the reaction [Poly I-C results in increased expression of IRF3 mRNA]; Quercetin inhibits the reaction [Poly I-C results in increased expression of IRF3 mRNA]; Sodium Selenite inhibits the reaction [Poly I-C results in increased activity of IRF3 protein]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; [Vehicle Emissions analog co-treated with Poly I-C] affects the localization of IRF3 protein; Cannabidiol inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; Dronabinol inhibits the reaction [Poly I-C results in increased localization of IRF3 protein]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]
CTD PMID:16399790 PMID:18279804 PMID:18779317 PMID:19426678 PMID:25780039 PMID:32244040 NCBI chr 7:44,997,648...45,002,848
Ensembl chr 7:44,997,648...45,002,848
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression
multiple interactions
ISO Poly I-C results in increased expression of IRF7 mRNA
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Poly I-C results in increased expression of IRF7 mRNA]
IRF7 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; IRF7 protein mutant form affects the reaction [Nicotine inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]]; IRF7 protein mutant form inhibits the reaction [Nicotine inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of DDX58 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIH1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IFIT1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IRF7 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IRF9 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of ISG15 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of OAS1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT1 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT2 mRNA]; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased secretion of IFNB1 protein]; Nicotine inhibits the reaction [Poly I-C results in increased expression of IRF7 mRNA]
CTD PMID:28726298 PMID:31154625 NCBI chr 7:141,263,183...141,266,499
Ensembl chr 7:141,262,706...141,266,481
JBrowse link
G Irf9 interferon regulatory factor 9 multiple interactions
increases expression
ISO IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of IRF9 mRNA] CTD PMID:31154625 NCBI chr14:55,603,985...55,610,030
Ensembl chr14:55,603,571...55,610,030
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions
increases expression
ISO IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of ISG15 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of ISG15 mRNA] CTD PMID:31154625 NCBI chr 4:156,199,424...156,200,818
Ensembl chr 4:156,199,455...156,200,796
JBrowse link
G Itgam integrin alpha M increases expression ISO Poly I-C results in increased expression of ITGAM mRNA; Poly I-C results in increased expression of ITGAM protein CTD PMID:27317300 NCBI chr 7:128,062,640...128,118,491
Ensembl chr 7:128,062,640...128,118,491
JBrowse link
G Jcad junctional cadherin 5 associated multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of JCAD mRNA CTD PMID:26923065 NCBI chr18:4,590,792...4,682,869
Ensembl chr18:4,634,878...4,682,869
JBrowse link
G Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KCNA2 mRNA CTD PMID:26923065 NCBI chr 3:107,090,883...107,115,005
Ensembl chr 3:107,101,146...107,115,005
JBrowse link
G Kcnip4 Kv channel interacting protein 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KCNIP4 mRNA CTD PMID:26923065 NCBI chr 5:48,389,503...49,525,122
Ensembl chr 5:48,389,502...49,524,907
JBrowse link
G Kcnq5 potassium voltage-gated channel, subfamily Q, member 5 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KCNQ5 mRNA CTD PMID:26923065 NCBI chr 1:21,398,399...21,962,650
Ensembl chr 1:21,398,403...21,961,942
JBrowse link
G Kif5b kinesin family member 5B multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KIF5B mRNA CTD PMID:26923065 NCBI chr18:6,201,005...6,241,524
Ensembl chr18:6,201,002...6,242,174
JBrowse link
G Kif5c kinesin family member 5C multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KIF5C mRNA CTD PMID:26923065 NCBI chr 2:49,619,286...49,774,778
Ensembl chr 2:49,619,298...49,774,778
JBrowse link
G Klf4 Kruppel-like factor 4 (gut) multiple interactions
increases expression
ISO Poly I-C promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]
Poly I-C results in increased expression of KLF4 protein
CTD PMID:29486283 NCBI chr 4:55,527,137...55,532,475
Ensembl chr 4:55,527,143...55,532,466
JBrowse link
G Klrk1 killer cell lectin-like receptor subfamily K, member 1 increases expression EXP Poly I-C results in increased expression of KLRK1 mRNA; Poly I-C results in increased expression of KLRK1 protein CTD PMID:16472598 NCBI chr 6:129,610,323...129,623,903
Ensembl chr 6:129,610,323...129,623,864
JBrowse link
G Kpna3 karyopherin (importin) alpha 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of KPNA3 mRNA CTD PMID:26923065 NCBI chr14:61,365,186...61,439,947
Ensembl chr14:61,365,211...61,439,874
JBrowse link
G Lsm14b LSM family member 14B multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of LSM14B mRNA CTD PMID:26923065 NCBI chr 2:180,024,900...180,035,466
Ensembl chr 2:180,024,987...180,035,465
JBrowse link
G Mal2 mal, T cell differentiation protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAL2 mRNA CTD PMID:26923065 NCBI chr15:54,571,366...54,602,846
Ensembl chr15:54,571,192...54,602,847
JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 increases phosphorylation ISO Poly I-C results in increased phosphorylation of MAP3K11 protein CTD PMID:17698565 NCBI chr19:5,688,411...5,702,865
Ensembl chr19:5,688,742...5,702,865
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation
increases phosphorylation
multiple interactions
EXP Poly I-C results in decreased phosphorylation of MAPK1 protein
Poly I-C results in increased phosphorylation of MAPK1 protein
Suramin inhibits the reaction [Poly I-C results in decreased phosphorylation of MAPK1 protein]; trametinib inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK1 protein]
CTD PMID:23516405 PMID:25780039 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation
increases phosphorylation
multiple interactions
EXP Poly I-C results in decreased phosphorylation of MAPK3 protein
Poly I-C results in increased phosphorylation of MAPK3 protein
Suramin inhibits the reaction [Poly I-C results in decreased phosphorylation of MAPK3 protein]; trametinib inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Poly I-C results in increased phosphorylation of MAPK3 protein]
CTD PMID:23516405 PMID:25780039 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mapk4 mitogen-activated protein kinase 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAPK4 mRNA CTD PMID:26923065 NCBI chr18:73,928,486...74,065,434
Ensembl chr18:73,928,486...74,065,359
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAPK9 mRNA CTD PMID:26923065 NCBI chr11:49,846,728...49,886,421
Ensembl chr11:49,846,751...49,886,421
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MAPRE1 mRNA CTD PMID:26923065 NCBI chr 2:153,741,287...153,773,317
Ensembl chr 2:153,741,274...153,773,310
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MARCHF7 mRNA CTD PMID:26923065 NCBI chr 2:60,209,936...60,248,385
Ensembl chr 2:60,209,887...60,250,676
JBrowse link
G Mblac2 metallo-beta-lactamase domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MBLAC2 mRNA CTD PMID:26923065 NCBI chr13:81,711,417...81,753,275
Ensembl chr13:81,711,341...81,753,275
JBrowse link
G Mbp myelin basic protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MBP mRNA CTD PMID:26923065 NCBI chr18:82,475,091...82,585,637
Ensembl chr18:82,475,146...82,585,637
JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MEF2C mRNA CTD PMID:26923065 NCBI chr13:83,504,017...83,667,079
Ensembl chr13:83,504,034...83,667,080
JBrowse link
G Micos13 mitochondrial contact site and cristae organizing system subunit 13 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of MICOS13 mRNA CTD PMID:26923065 NCBI chr17:56,607,452...56,609,771
Ensembl chr17:56,607,452...56,609,771
JBrowse link
G Micu3 mitochondrial calcium uptake family, member 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MICU3 mRNA CTD PMID:26923065 NCBI chr 8:40,307,438...40,388,782
Ensembl chr 8:40,307,458...40,386,308
JBrowse link
G Mir155 microRNA 155 multiple interactions
increases expression
EXP MIR155 mRNA inhibits the reaction [Progesterone inhibits the reaction [Poly I-C results in increased expression of MIR155 mRNA]]; Progesterone inhibits the reaction [Poly I-C results in increased expression of MIR155 mRNA] CTD PMID:22546503 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Mir26a-1 microRNA 26a-1 multiple interactions ISO MIR26A mRNA inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF protein] CTD PMID:24423102 NCBI chr 9:119,031,796...119,031,885
Ensembl chr 9:119,031,796...119,031,885
JBrowse link
G Mrps15 mitochondrial ribosomal protein S15 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of MRPS15 mRNA CTD PMID:26923065 NCBI chr 4:126,046,928...126,055,536
Ensembl chr 4:126,046,925...126,055,532
JBrowse link
G Msi1 musashi RNA-binding protein 1 multiple interactions ISO Poly I-C promotes the reaction [MSI1 protein results in increased expression of KLF4 protein]; Poly I-C promotes the reaction [MSI1 protein results in increased expression of MYC protein]; Poly I-C promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]; Poly I-C promotes the reaction [MSI1 protein results in increased expression of SOX2 protein] CTD PMID:29486283 NCBI chr 5:115,359,059...115,455,698
Ensembl chr 5:115,429,599...115,455,698
JBrowse link
G Mtpn myotrophin multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MTPN mRNA CTD PMID:26923065 NCBI chr 6:35,508,824...35,539,888
Ensembl chr 6:35,508,906...35,539,888
JBrowse link
G Mtrex Mtr4 exosome RNA helicase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of MTREX mRNA CTD PMID:26923065 NCBI chr13:112,867,780...112,927,380
Ensembl chr13:112,867,418...112,927,398
JBrowse link
G Mx1 MX dynamin-like GTPase 1 increases expression ISO Poly I-C results in increased expression of MX1 mRNA CTD PMID:17669408 PMID:22558189 NCBI chr16:97,447,035...97,462,906
Ensembl chr16:97,447,035...97,462,907
JBrowse link
G Myc myelocytomatosis oncogene increases expression
multiple interactions
ISO Poly I-C results in increased expression of MYC protein
Poly I-C promotes the reaction [MSI1 protein results in increased expression of MYC protein]
CTD PMID:29486283 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 increases expression
multiple interactions
EXP Poly I-C results in increased expression of MYD88 mRNA
cinnamic aldehyde inhibits the reaction [Poly I-C results in increased expression of MYD88 mRNA]
CTD PMID:18306459 NCBI chr 9:119,335,934...119,340,018
Ensembl chr 9:119,335,934...119,341,411
JBrowse link
G Naa60 N(alpha)-acetyltransferase 60, NatF catalytic subunit multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NAA60 mRNA CTD PMID:26923065 NCBI chr16:3,872,496...3,904,781
Ensembl chr16:3,872,375...3,904,770
JBrowse link
G Napb N-ethylmaleimide sensitive fusion protein attachment protein beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NAPB mRNA CTD PMID:26923065 NCBI chr 2:148,693,985...148,732,425
Ensembl chr 2:148,693,985...148,732,467
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NAPEPLD mRNA CTD PMID:26923065 NCBI chr 5:21,662,901...21,701,622
Ensembl chr 5:21,662,901...21,701,396
JBrowse link
G Nbea neurobeachin multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NBEA mRNA CTD PMID:26923065 NCBI chr 3:55,625,195...56,183,748
Ensembl chr 3:55,625,195...56,183,701
JBrowse link
G Ndst3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NDST3 mRNA CTD PMID:26923065 NCBI chr 3:123,526,166...123,691,174
Ensembl chr 3:123,526,166...123,690,853
JBrowse link
G Necab1 N-terminal EF-hand calcium binding protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NECAB1 mRNA CTD PMID:26923065 NCBI chr 4:14,952,245...15,149,804
Ensembl chr 4:14,952,245...15,149,794
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases phosphorylation
multiple interactions
ISO Poly I-C results in increased phosphorylation of NFKBIA protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; [Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased degradation of NFKBIA protein]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]
CTD PMID:18779317 PMID:20932985 PMID:23688403 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nlgn3 neuroligin 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NLGN3 mRNA CTD PMID:26923065 NCBI chr  X:101,299,179...101,321,350
Ensembl chr  X:101,299,168...101,325,963
JBrowse link
G Nmu neuromedin U multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of NMU mRNA CTD PMID:26923065 NCBI chr 5:76,333,495...76,363,777
Ensembl chr 5:76,333,495...76,363,788
JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression
multiple interactions
EXP
ISO
Poly I-C results in increased expression of NOS2 mRNA; Poly I-C results in increased expression of NOS2 protein
Diclofenac promotes the reaction [Poly I-C results in increased expression of NOS2 mRNA]
pitavastatin inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]; Pravastatin inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of NOS2 mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of NOS2 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of NOS2 protein]
CTD PMID:17321468 PMID:18279804 PMID:18323514 PMID:21195166 PMID:23939143 PMID:30726814 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nrsn1 neurensin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of NRSN1 mRNA CTD PMID:26923065 NCBI chr13:25,252,039...25,269,996
Ensembl chr13:25,252,040...25,270,502
JBrowse link
G Nuf2 NUF2, NDC80 kinetochore complex component multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of NUF2 mRNA CTD PMID:26923065 NCBI chr 1:169,497,934...169,531,464
Ensembl chr 1:169,497,934...169,531,464
JBrowse link
G Oas1g 2'-5' oligoadenylate synthetase 1G increases expression
multiple interactions
ISO Poly I-C results in increased expression of OAS1 mRNA
[[Poly I-C co-treated with Interferon-alpha] results in increased activity of OAS1 protein] which results in increased abundance of 2',5'-oligoadenylate; [Poly I-C co-treated with Interferon-alpha] results in increased activity of OAS1 protein; IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of OAS1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of OAS1 mRNA]
CTD PMID:17669408 PMID:26055709 PMID:31154625 NCBI chr 5:120,876,142...120,887,613
Ensembl chr 5:120,876,142...120,887,613
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Poly I-C results in increased expression of OAS2 mRNA CTD PMID:22558189 NCBI chr 5:120,730,333...120,749,886
Ensembl chr 5:120,730,333...120,749,853
JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 decreases expression
multiple interactions
EXP Poly I-C results in decreased expression of P2RX7 protein
Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RX7 protein]
CTD PMID:23516405 NCBI chr 5:122,643,927...122,692,336
Ensembl chr 5:122,643,911...122,691,432
JBrowse link
G P2ry2 purinergic receptor P2Y, G-protein coupled 2 decreases expression
multiple interactions
EXP Poly I-C results in decreased expression of P2RY2 protein
Suramin inhibits the reaction [Poly I-C results in decreased expression of P2RY2 protein]
CTD PMID:23516405 NCBI chr 7:100,996,568...101,012,053
Ensembl chr 7:100,996,568...101,012,866
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PAK2 mRNA CTD PMID:26923065 NCBI chr16:32,016,290...32,079,342
Ensembl chr16:32,016,290...32,079,342
JBrowse link
G Pard6g par-6 family cell polarity regulator gamma multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PARD6G mRNA CTD PMID:26923065 NCBI chr18:80,046,830...80,119,640
Ensembl chr18:80,046,890...80,119,639
JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PCMTD1 mRNA CTD PMID:26923065 NCBI chr 1:7,087,077...7,173,628
Ensembl chr 1:7,088,920...7,173,628
JBrowse link
G Pdap1 PDGFA associated protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PDAP1 mRNA CTD PMID:26923065 NCBI chr 5:145,128,770...145,140,025
Ensembl chr 5:145,128,769...145,140,238
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PDCD6IP mRNA CTD PMID:26923065 NCBI chr 9:113,651,744...113,708,279
Ensembl chr 9:113,651,744...113,708,259
JBrowse link
G Phactr1 phosphatase and actin regulator 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PHACTR1 mRNA CTD PMID:26923065 NCBI chr13:42,680,374...43,138,526
Ensembl chr13:42,680,623...43,138,526
JBrowse link
G Phf7 PHD finger protein 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PHF7 mRNA CTD PMID:26923065 NCBI chr14:31,237,689...31,251,344
Ensembl chr14:31,237,689...31,251,317
JBrowse link
G Pkib protein kinase inhibitor beta, cAMP dependent, testis specific multiple interactions
decreases expression
ISO [Poly I-C co-treated with HU 211] results in decreased expression of PKIB mRNA
Poly I-C results in decreased expression of PKIB mRNA
CTD PMID:26923065 NCBI chr10:57,631,981...57,741,112
Ensembl chr10:57,631,981...57,741,112
JBrowse link
G Plcb1 phospholipase C, beta 1 increases expression EXP Poly I-C results in increased expression of PLCB1 mRNA CTD PMID:24889602 NCBI chr 2:134,786,164...135,475,258
Ensembl chr 2:134,786,067...135,475,258
JBrowse link
G Plcxd2 phosphatidylinositol-specific phospholipase C, X domain containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PLCXD2 mRNA CTD PMID:26923065 NCBI chr16:45,959,261...46,010,413
Ensembl chr16:45,959,263...46,010,218
JBrowse link
G Plekha8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PLEKHA8 mRNA CTD PMID:26923065 NCBI chr 6:54,595,111...54,645,823
Ensembl chr 6:54,595,111...54,645,839
JBrowse link
G Plppr4 phospholipid phosphatase related 4 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PLPPR4 mRNA CTD PMID:26923065 NCBI chr 3:117,319,145...117,360,876
Ensembl chr 3:117,319,139...117,360,876
JBrowse link
G Pmvk phosphomevalonate kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PMVK mRNA CTD PMID:26923065 NCBI chr 3:89,454,541...89,469,014
Ensembl chr 3:89,454,541...89,469,013
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 increases expression
multiple interactions
ISO Poly I-C results in increased expression of POU5F1 protein
Poly I-C promotes the reaction [MSI1 protein results in increased expression of POU5F1 protein]
CTD PMID:29486283 NCBI chr17:35,506,032...35,510,777
Ensembl chr17:35,506,018...35,510,772
JBrowse link
G Prf1 perforin 1 (pore forming protein) multiple interactions
increases expression
ISO Particulate Matter inhibits the reaction [Poly I-C results in increased expression of PRF1 protein]; Vehicle Emissions inhibits the reaction [Poly I-C results in increased expression of PRF1 protein]
Poly I-C results in increased expression of PRF1 mRNA; Poly I-C results in increased expression of PRF1 protein
CTD PMID:23618096 NCBI chr10:61,297,751...61,304,684
Ensembl chr10:61,297,833...61,304,680
JBrowse link
G Prkci protein kinase C, iota multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of PRKCI mRNA CTD PMID:26923065 NCBI chr 3:30,995,742...31,052,740
Ensembl chr 3:30,995,747...31,052,959
JBrowse link
G Prl2b1 prolactin family 2, subfamily b, member 1 multiple interactions
increases expression
EXP IL6 protein affects the reaction [Poly I-C results in increased expression of PRL2B1 mRNA] CTD PMID:21195166 NCBI chr13:27,383,345...27,390,846
Ensembl chr13:27,383,339...27,390,846
JBrowse link
G Prodh2 proline dehydrogenase (oxidase) 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of PRODH2 mRNA CTD PMID:26923065 NCBI chr 7:30,493,586...30,513,402
Ensembl chr 7:30,493,622...30,513,402
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
EXP Poly I-C results in increased expression of PTGS2 protein
[Poly I-C results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] which results in increased expression of PTGS2 mRNA; Poly I-C promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Poly I-C results in increased expression of PTGS2 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of PTGS2 protein]
CTD PMID:16116226 PMID:18279804 PMID:24889602 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Pvalb parvalbumin multiple interactions ISO [Poly I-C co-treated with Cannabidiol] results in increased expression of PVALB protein CTD PMID:31326506 NCBI chr15:78,191,112...78,206,400
Ensembl chr15:78,191,114...78,206,400
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RAC1 mRNA CTD PMID:26923065 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rdm1 RAD52 motif 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RDM1 mRNA CTD PMID:26923065 NCBI chr11:101,627,242...101,636,089
Ensembl chr11:101,627,195...101,636,100
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) affects localization
increases phosphorylation
multiple interactions
ISO Poly I-C affects the localization of RELA protein
Poly I-C results in increased phosphorylation of RELA protein
TP53 protein affects the reaction [Poly I-C affects the localization of RELA protein]
CTD PMID:18779317 PMID:24709138 PMID:27836898 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP Poly I-C results in increased expression of RGS4 mRNA CTD PMID:24889602 NCBI chr 1:169,741,477...169,747,642
Ensembl chr 1:169,741,477...169,747,642
JBrowse link
G Rimbp2 RIMS binding protein 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RIMBP2 mRNA CTD PMID:26923065 NCBI chr 5:128,757,788...128,953,644
Ensembl chr 5:128,757,791...128,953,486
JBrowse link
G Rnf141 ring finger protein 141 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RNF141 mRNA CTD PMID:26923065 NCBI chr 7:110,799,469...110,844,452
Ensembl chr 7:110,800,432...110,844,457
JBrowse link
G Rpl31 ribosomal protein L31 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RPL31 mRNA CTD PMID:26923065 NCBI chr 1:39,367,851...39,371,911
Ensembl chr 1:39,367,842...39,371,911
JBrowse link
G Rps6kb2 ribosomal protein S6 kinase, polypeptide 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of RPS6KB2 mRNA CTD PMID:26923065 NCBI chr19:4,156,792...4,163,383
Ensembl chr19:4,153,991...4,163,354
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of RTN4RL1 mRNA CTD PMID:26923065 NCBI chr11:75,193,993...75,267,769
Ensembl chr11:75,193,783...75,267,769
JBrowse link
G S100a3 S100 calcium binding protein A3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of S100A3 mRNA CTD PMID:26923065 NCBI chr 3:90,560,356...90,602,706
Ensembl chr 3:90,584,659...90,602,702
JBrowse link
G Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SEMA6D mRNA CTD PMID:26923065 NCBI chr 2:124,089,943...124,667,789
Ensembl chr 2:124,089,969...124,667,770
JBrowse link
G Septin6 septin 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SEPTIN6 mRNA CTD PMID:26923065 NCBI chr  X:36,911,272...36,990,036
Ensembl chr  X:36,911,326...36,991,794
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions
increases expression
ISO Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein]; Hydroxychloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; Hydroxychloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]
Poly I-C results in increased expression of SERPINE1 mRNA; Poly I-C results in increased expression of SERPINE1 protein
CTD PMID:30341573 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268
JBrowse link
G Sesn2 sestrin 2 increases expression EXP Poly I-C results in increased expression of SESN2 mRNA CTD PMID:25637945 NCBI chr 4:132,492,804...132,510,456
Ensembl chr 4:132,492,032...132,510,501
JBrowse link
G Sgtb small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SGTB mRNA CTD PMID:26923065 NCBI chr13:104,109,723...104,141,861
Ensembl chr13:104,109,741...104,141,735
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SH3RF1 mRNA CTD PMID:26923065 NCBI chr 8:61,224,083...61,465,293
Ensembl chr 8:61,223,872...61,396,071
JBrowse link
G Shroom2 shroom family member 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SHROOM2 mRNA CTD PMID:26923065 NCBI chr  X:152,609,509...152,770,788
Ensembl chr  X:152,609,509...152,769,465
JBrowse link
G Sidt1 SID1 transmembrane family, member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SIDT1 mRNA CTD PMID:26923065 NCBI chr16:44,240,177...44,333,212
Ensembl chr16:44,240,180...44,333,196
JBrowse link
G Slc14a1 solute carrier family 14 (urea transporter), member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC14A1 mRNA CTD PMID:26923065 NCBI chr18:78,100,091...78,142,119
Ensembl chr18:78,100,091...78,142,119
JBrowse link
G Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC17A7 mRNA CTD PMID:26923065 NCBI chr 7:45,163,921...45,176,139
Ensembl chr 7:45,163,949...45,176,142
JBrowse link
G Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC25A12 mRNA CTD PMID:26923065 NCBI chr 2:71,274,270...71,367,781
Ensembl chr 2:71,271,063...71,367,749
JBrowse link
G Slc25a14 solute carrier family 25 (mitochondrial carrier, brain), member 14 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC25A14 mRNA CTD PMID:26923065 NCBI chr  X:48,623,418...48,662,298
Ensembl chr  X:48,623,413...48,662,294
JBrowse link
G Slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC2A13 mRNA CTD PMID:26923065 NCBI chr15:91,267,691...91,573,261
Ensembl chr15:91,267,696...91,573,261
JBrowse link
G Slc3a1 solute carrier family 3, member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC3A1 mRNA CTD PMID:26923065 NCBI chr17:85,028,347...85,064,241
Ensembl chr17:85,028,376...85,064,236
JBrowse link
G Slc4a10 solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SLC4A10 mRNA CTD PMID:26923065 NCBI chr 2:62,046,472...62,326,743
Ensembl chr 2:62,046,462...62,326,730
JBrowse link
G Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SMARCD1 mRNA CTD PMID:26923065 NCBI chr15:99,702,287...99,713,995
Ensembl chr15:99,702,129...99,713,991
JBrowse link
G Snrk SNF related kinase multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SNRK mRNA CTD PMID:26923065 NCBI chr 9:122,117,266...122,169,702
Ensembl chr 9:122,117,266...122,169,702
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression
multiple interactions
EXP Poly I-C results in increased expression of SOCS1 mRNA
Progesterone promotes the reaction [Poly I-C results in increased expression of SOCS1 mRNA]
CTD PMID:22546503 NCBI chr16:10,783,808...10,785,536
Ensembl chr16:10,782,240...10,785,536
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression EXP Poly I-C results in increased expression of SOCS3 mRNA CTD PMID:21195166 NCBI chr11:117,966,079...117,970,336
Ensembl chr11:117,966,079...117,970,047
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression ISO Poly I-C results in increased expression of SOD2 mRNA CTD PMID:23939143 NCBI chr17:13,007,839...13,018,119
Ensembl chr17:13,006,846...13,040,063
JBrowse link
G Sox2 SRY (sex determining region Y)-box 2 increases expression
multiple interactions
ISO Poly I-C results in increased expression of SOX2 protein
Poly I-C promotes the reaction [MSI1 protein results in increased expression of SOX2 protein]
CTD PMID:29486283 NCBI chr 3:34,649,995...34,652,461
Ensembl chr 3:34,650,405...34,652,461
JBrowse link
G Spag6l sperm associated antigen 6-like decreases expression ISO Poly I-C results in decreased expression of SPAG6 mRNA CTD PMID:26923065 NCBI chr16:16,753,016...16,829,363
Ensembl chr16:16,753,016...16,829,456
JBrowse link
G Srsf12 serine and arginine-rich splicing factor 12 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SRSF12 mRNA CTD PMID:26923065 NCBI chr 4:33,208,991...33,233,343
Ensembl chr 4:33,208,991...33,233,340
JBrowse link
G Srsf7 serine and arginine-rich splicing factor 7 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SRSF7 mRNA CTD PMID:26923065 NCBI chr17:80,200,080...80,207,369
Ensembl chr17:80,200,080...80,207,307
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases phosphorylation
increases expression
multiple interactions
EXP
ISO
Poly I-C results in increased phosphorylation of STAT1 protein
Poly I-C results in increased expression of STAT1 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT1 mRNA]; Nicotine inhibits the reaction [Poly I-C results in increased expression of STAT1 mRNA]
sodium arsenite inhibits the reaction [Poly I-C results in increased phosphorylation of STAT1 protein]
CTD PMID:30726814 PMID:31154625 NCBI chr 1:52,119,438...52,161,865
Ensembl chr 1:52,119,440...52,161,865
JBrowse link
G Stat2 signal transducer and activator of transcription 2 increases expression
multiple interactions
ISO Poly I-C results in increased expression of STAT2 mRNA
IRF7 protein mutant form inhibits the reaction [Poly I-C results in increased expression of STAT2 mRNA]
CTD PMID:31154625 NCBI chr10:128,270,498...128,292,853
Ensembl chr10:128,270,559...128,292,849
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP IL6 protein affects the reaction [Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein]; Poly I-C results in increased phosphorylation of and results in increased activity of STAT3 protein CTD PMID:21195166 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Stxbp6 syntaxin binding protein 6 (amisyn) multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of STXBP6 mRNA CTD PMID:26923065 NCBI chr12:44,852,484...45,075,118
Ensembl chr12:44,852,484...45,074,709
JBrowse link
G Svip small VCP/p97-interacting protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SVIP mRNA CTD PMID:26923065 NCBI chr 7:51,997,161...52,006,018
Ensembl chr 7:51,997,171...52,006,018
JBrowse link
G Syt11 synaptotagmin XI multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of SYT11 mRNA CTD PMID:26923065 NCBI chr 3:88,744,699...88,775,159
Ensembl chr 3:88,744,700...88,775,164
JBrowse link
G Tbc1d9 TBC1 domain family, member 9 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TBC1D9 mRNA CTD PMID:26923065 NCBI chr 8:83,165,352...83,272,940
Ensembl chr 8:83,165,352...83,272,934
JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions
increases phosphorylation
EXP APPL1 protein promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein]; bafilomycin A1 promotes the reaction [Poly I-C results in increased phosphorylation of TBK1 protein] CTD PMID:25780039 NCBI chr10:121,546,455...121,586,794
Ensembl chr10:121,546,455...121,586,787
JBrowse link
G Terf2ip telomeric repeat binding factor 2, interacting protein multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TERF2IP mRNA CTD PMID:26923065 NCBI chr 8:112,011,359...112,020,528
Ensembl chr 8:112,011,398...112,020,528
JBrowse link
G Tfb1m transcription factor B1, mitochondrial multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of TFB1M mRNA CTD PMID:26923065 NCBI chr17:3,519,250...3,557,796
Ensembl chr17:3,519,256...3,557,781
JBrowse link
G Thy1 thymus cell antigen 1, theta multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of THY1 mRNA CTD PMID:26923065 NCBI chr 9:44,043,384...44,048,579
Ensembl chr 9:44,043,384...44,048,579
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 increases expression ISO Poly I-C results in increased expression of TICAM1 mRNA CTD PMID:21418039 NCBI chr17:56,269,462...56,276,767
Ensembl chr17:56,269,319...56,276,786
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression EXP Poly I-C results in increased expression of TIMP1 mRNA CTD PMID:21195166 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735
JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO Poly I-C results in increased expression of TLR2 mRNA CTD PMID:17669408 NCBI chr 3:83,836,272...83,841,824
Ensembl chr 3:83,836,272...83,841,767
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions
increases activity
increases expression
ISO
EXP
[[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of IL12B protein; [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of TNF protein; [Poly I-C binds to TLR3 protein] which affects the susceptibility to 1-aminopyrene; [Poly I-C binds to TLR3 protein] which affects the susceptibility to 1-nitropyrene; [Poly I-C binds to TLR3 protein] which affects the susceptibility to pyrene; [Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of TLR3 mRNA; [Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of TLR3 protein; Chloroquine inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]; Poly I-C binds to and results in increased activity of TLR3 protein; Quinacrine inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]; TLR3 mRNA promotes the reaction [Poly I-C results in increased expression of SERPINE1 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; TLR3 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
MIR26A mRNA inhibits the reaction [Poly I-C results in increased activity of TLR3 protein]
Poly I-C results in increased expression of TLR3 mRNA
cinnamic aldehyde inhibits the reaction [Poly I-C results in increased expression of TLR3 mRNA]
CTD PMID:16399790 PMID:17669408 PMID:18306459 PMID:18779317 PMID:21398612 PMID:21418039 PMID:23266719 PMID:23458896 PMID:24423102 PMID:25780039 PMID:26682054 PMID:27385120 PMID:28003376 PMID:30341573 PMID:32244040 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Tlr7 toll-like receptor 7 increases expression ISO Poly I-C results in increased expression of TLR7 mRNA CTD PMID:17669408 NCBI chr  X:167,303,380...167,330,574
Ensembl chr  X:167,304,929...167,330,558
JBrowse link
G Tmem266 transmembrane protein 266 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of TMEM266 mRNA CTD PMID:26923065 NCBI chr 9:55,326,913...55,438,345
Ensembl chr 9:55,326,913...55,438,345
JBrowse link
G Tmem273 transmembrane protein 273 multiple interactions ISO [Poly I-C co-treated with HU 211] results in increased expression of TMEM273 mRNA CTD PMID:26923065 NCBI chr14:32,785,894...32,817,969
Ensembl chr14:32,785,963...32,817,984
JBrowse link
G Tmprss2 transmembrane protease, serine 2 decreases response to substance EXP TMPRSS2 gene mutant form results in decreased susceptibility to Poly I-C CTD PMID:30626688 NCBI chr16:97,564,682...97,659,541
Ensembl chr16:97,564,682...97,611,195
JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TMX1 mRNA CTD PMID:26923065 NCBI chr12:70,453,154...70,467,624
Ensembl chr12:70,453,095...70,468,040
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
ISO
EXP
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane promotes the reaction [Poly I-C results in increased expression of TNF protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of TNF protein]; [[Poly I-C binds to and results in increased activity of TLR3 protein] which co-treated with Nanotubes, Carbon] results in increased secretion of TNF protein; CEP-11004 inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; CpG ODN 2006 inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of TNF protein]; N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; RTKI cpd inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [Poly I-C results in increased secretion of TNF protein]
Poly I-C results in increased expression of TNF mRNA; Poly I-C results in increased expression of TNF protein
cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [Poly I-C results in increased expression of TNF protein]
APPL1 protein inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Citrinin inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Citrinin inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Ethanol inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Ethanol inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Ethanol promotes the reaction [Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]]; Hydroxamic Acids analog inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Hydroxamic Acids analog promotes the reaction [Dimethyl Sulfoxide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]]; Luteolin inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; sodium arsenite inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]
CTD PMID:16687389 PMID:17238832 PMID:17321468 PMID:17669408 PMID:17698565 PMID:17868967 PMID:18323514 PMID:19426678 PMID:19500611 PMID:20932985 PMID:22319556 PMID:22771370 PMID:23266719 PMID:23618096 PMID:23939143 PMID:24423102 PMID:25780039 PMID:27385120 PMID:28316773 PMID:28726298 PMID:30017638 PMID:30726814 PMID:30836164 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 increases expression EXP Poly I-C results in increased expression of TNFSF10 mRNA; Poly I-C results in increased expression of TNFSF10 protein CTD PMID:16472598 NCBI chr 3:27,317,077...27,339,665
Ensembl chr 3:27,317,028...27,342,427
JBrowse link
G Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TNKS2 mRNA CTD PMID:26923065 NCBI chr19:36,834,129...36,893,477
Ensembl chr19:36,834,232...36,893,477
JBrowse link
G Tpd52 tumor protein D52 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TPD52 mRNA CTD PMID:26923065 NCBI chr 3:8,926,530...9,005,393
Ensembl chr 3:8,925,593...9,004,723
JBrowse link
G Traf6 TNF receptor-associated factor 6 multiple interactions ISO TRAF6 mutant form inhibits the reaction [Vehicle Emissions analog promotes the reaction [Poly I-C results in increased expression of IL6 mRNA]] CTD PMID:16399790 NCBI chr 2:101,678,420...101,701,668
Ensembl chr 2:101,678,429...101,701,669
JBrowse link
G Trim2 tripartite motif-containing 2 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TRIM2 mRNA CTD PMID:26923065 NCBI chr 3:84,160,439...84,308,352
Ensembl chr 3:84,160,439...84,306,877
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO TP53 protein affects the reaction [Poly I-C affects the localization of RELA protein]; TP53 protein affects the reaction [Poly I-C results in increased expression of CXCL8 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of IRF3 protein]; TP53 protein affects the reaction [Poly I-C results in increased phosphorylation of NFKBIA protein]; TP53 results in increased susceptibility to [Poly I-C co-treated with Fluorouracil] CTD PMID:18779317 PMID:20367642 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions
increases expression
ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol promotes the reaction [Poly I-C results in increased expression of TSLP protein]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]]; 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-(4-(2H-tetrazol-5-yl)butyl)piperidine inhibits the reaction [Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]]; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA; [Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; amorolfine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; butenafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Estradiol promotes the reaction [Poly I-C results in increased expression of TSLP protein]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; helenalin inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP mRNA]; IL4 protein promotes the reaction [Poly I-C results in increased expression of TSLP protein]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Itraconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Ketoconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; luliconazole inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP mRNA]; Terbinafine inhibits the reaction [[Poly I-C co-treated with IL4 protein] results in increased expression of TSLP protein]
Poly I-C results in increased expression of TSLP mRNA; Poly I-C results in increased expression of TSLP protein
CTD PMID:23688403 PMID:30017638 NCBI chr18:32,815,383...32,819,799
Ensembl chr18:32,815,383...32,819,797
JBrowse link
G Tspyl5 testis-specific protein, Y-encoded-like 5 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TSPYL5 mRNA CTD PMID:26923065 NCBI chr15:33,683,875...33,687,883
Ensembl chr15:33,683,875...33,687,884
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TTC3 mRNA CTD PMID:26923065 NCBI chr16:94,370,625...94,469,222
Ensembl chr16:94,370,618...94,469,343
JBrowse link
G Twist1 twist basic helix-loop-helix transcription factor 1 decreases expression ISO Poly I-C results in decreased expression of TWIST1 mRNA CTD PMID:26923065 NCBI chr12:33,957,671...33,959,831
Ensembl chr12:33,957,671...33,959,829
JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of TWSG1 mRNA CTD PMID:26923065 NCBI chr17:65,923,065...65,951,187
Ensembl chr17:65,921,972...65,951,226
JBrowse link
G Txn1 thioredoxin 1 multiple interactions
increases expression
ISO Diclofenac inhibits the reaction [Poly I-C results in increased expression of TXN1 mRNA] CTD PMID:23939143 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Ubl4a ubiquitin-like 4A multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of UBL4A mRNA CTD PMID:26923065 NCBI chr  X:74,365,718...74,368,548
Ensembl chr  X:74,365,718...74,373,218
JBrowse link
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of UBR1 mRNA CTD PMID:26923065 NCBI chr 2:120,860,272...120,970,760
Ensembl chr 2:120,860,269...120,970,715
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases expression ISO Poly I-C results in decreased expression of UGT2B1 mRNA CTD PMID:23939143 NCBI chr 5:86,916,639...86,926,503
Ensembl chr 5:86,916,638...86,926,530
JBrowse link
G Usp32 ubiquitin specific peptidase 32 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of USP32 mRNA CTD PMID:26923065 NCBI chr11:84,984,437...85,140,281
Ensembl chr11:84,984,442...85,140,161
JBrowse link
G Vsnl1 visinin-like 1 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of VSNL1 mRNA CTD PMID:26923065 NCBI chr12:11,325,257...11,436,578
Ensembl chr12:11,325,242...11,436,613
JBrowse link
G Wac WW domain containing adaptor with coiled-coil multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of WAC mRNA CTD PMID:26923065 NCBI chr18:7,868,825...7,929,028
Ensembl chr18:7,868,832...7,929,028
JBrowse link
G Wdr47 WD repeat domain 47 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of WDR47 mRNA CTD PMID:26923065 NCBI chr 3:108,591,223...108,645,719
Ensembl chr 3:108,591,279...108,645,719
JBrowse link
G Zbtb6 zinc finger and BTB domain containing 6 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZBTB6 mRNA CTD PMID:26923065 NCBI chr 2:37,425,500...37,430,919
Ensembl chr 2:37,425,500...37,443,171
JBrowse link
G Zdhhc21 zinc finger, DHHC domain containing 21 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZDHHC21 mRNA CTD PMID:26923065 NCBI chr 4:82,798,738...82,859,897
Ensembl chr 4:82,798,738...82,859,958
JBrowse link
G Zfp354c zinc finger protein 354C multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZFP354C mRNA CTD PMID:26923065 NCBI chr11:50,811,085...50,827,731
Ensembl chr11:50,811,086...50,827,724
JBrowse link
G Zfp664 zinc finger protein 664 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZFOC1 mRNA CTD PMID:26923065 NCBI chr 5:124,862,705...124,888,630
Ensembl chr 5:124,862,691...124,902,693
JBrowse link
G Zfp763 zinc finger protein 763 multiple interactions ISO [Poly I-C co-treated with HU 211] results in decreased expression of ZFP763 mRNA CTD PMID:26923065 NCBI chr17:33,016,864...33,033,381
Ensembl chr17:33,016,863...33,033,402
JBrowse link
sofosbuvir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klrc1 killer cell lectin-like receptor subfamily C, member 1 decreases expression ISO sofosbuvir co-treated with ledipasvir decreased expression of NCR1 protein in natural killer cells RGD PMID:31218578 RGD:40400920 NCBI chr 6:129,666,015...129,682,852
Ensembl chr 6:129,666,015...129,678,973
JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 affects expression ISO sofosbuvir co-treated with ledipasvir affects expression of NCR1 protein in natural killer cells RGD PMID:31218578 RGD:40400920 NCBI chr 7:4,337,715...4,345,184
Ensembl chr 7:4,337,724...4,345,164
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21727
    role 21705
      application 21214
        solvent 17569
          phosphoric acid 8015
            phosphoric acid derivative 7679
              organic phosphate 7678
                nucleoside phosphate 1699
                  nucleoside 5'-monophosphate 332
                    2'-deoxyribonucleoside monophosphate + 3
                    Ni(II)-pyridinium-3,5-bisthiocarboxylic acid mononucleotide 0
                    purine nucleoside monophosphate + 321
                    pyridinium-3,5-biscarboxylic acid mononucleotide + 0
                    pyridinium-3,5-bisthiocarboxylic acid mononucleotide 0
                    pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide 0
                    pyrimidine nucleoside monophosphate + 307
                    ribonucleoside monophosphate + 330
Path 2
Term Annotations click to browse term
  CHEBI ontology 21727
    subatomic particle 21713
      composite particle 21713
        hadron 21713
          baryon 21713
            nucleon 21713
              atomic nucleus 21713
                atom 21713
                  main group element atom 21629
                    p-block element atom 21629
                      chalcogen 20758
                        oxygen atom 20736
                          oxygen molecular entity 20736
                            hydroxides 20161
                              oxoacid 19444
                                pnictogen oxoacid 10419
                                  phosphorus oxoacid 9282
                                    phosphoric acids 8015
                                      phosphoric acid 8015
                                        phosphoric acid derivative 7679
                                          phosphate 7679
                                            organic phosphate 7678
                                              nucleoside phosphate 1699
                                                nucleoside 5'-monophosphate 332
                                                  2'-deoxyribonucleoside monophosphate + 3
                                                  Ni(II)-pyridinium-3,5-bisthiocarboxylic acid mononucleotide 0
                                                  purine nucleoside monophosphate + 321
                                                  pyridinium-3,5-biscarboxylic acid mononucleotide + 0
                                                  pyridinium-3,5-bisthiocarboxylic acid mononucleotide 0
                                                  pyridinium-3-carboxy-5-thiocarboxylic acid mononucleotide 0
                                                  pyrimidine nucleoside monophosphate + 307
                                                  ribonucleoside monophosphate + 330
paths to the root