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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2'-deoxyguanosine
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Accession:CHEBI:17172 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside having guanine as the nucleobase.
Synonyms:related_synonym: 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-9H-purin-6-ol;   9-(2-deoxy-beta-D-erythro-pentofuranosyl)-guanine;   Deoxyguanosine;   Formula=C10H13N5O4;   InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1;   InChIKey=YKBGVTZYEHREMT-KVQBGUIXSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1;   dG;   guanine deoxy nucleoside
 alt_id: CHEBI:14116;   CHEBI:19244;   CHEBI:23624;   CHEBI:42667;   CHEBI:42867;   CHEBI:42987;   CHEBI:4412
 xref: CAS:961-07-9;   HMDB:HMDB0000085;   KEGG:C00330
 xref_mesh: MESH:D003849
 xref: MetaCyc:DEOXYGUANOSINE;   PDBeChem:GNG;   Reaxys:39814;   Wikipedia:Deoxyguanosine


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2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO CYP3A4 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP3A4 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      atom 19771
        nonmetal atom 19654
          carbon atom 19573
            organic molecular entity 19573
              purines 2'-deoxy-D-ribonucleoside 14
                2'-deoxyguanosine 6
                  6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                  8,5'-cyclo-2'-deoxyguanosine 0
                  N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                  N(2)-carboxyethyl-2'-deoxyguanosine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            heteroorganic entity 19208
                              organochalcogen compound 18953
                                organooxygen compound 18879
                                  carbohydrates and carbohydrate derivatives 12262
                                    carbohydrate 12262
                                      carbohydrate derivative 11892
                                        glycosyl compound 10963
                                          N-glycosyl compound 5483
                                            nucleoside 5344
                                              deoxyribonucleoside 2738
                                                2'-deoxyribonucleoside 2217
                                                  purine 2'-deoxyribonucleoside 33
                                                    purines 2'-deoxy-D-ribonucleoside 14
                                                      2'-deoxyguanosine 6
                                                        6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                                                        8,5'-cyclo-2'-deoxyguanosine 0
                                                        N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                                                        N(2)-carboxyethyl-2'-deoxyguanosine + 0
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