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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2'-deoxyguanosine
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Accession:CHEBI:17172 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside having guanine as the nucleobase.
Synonyms:related_synonym: 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-9H-purin-6-ol;   9-(2-deoxy-beta-D-erythro-pentofuranosyl)-guanine;   Deoxyguanosine;   Formula=C10H13N5O4;   InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1;   InChIKey=YKBGVTZYEHREMT-KVQBGUIXSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1;   dG;   guanine deoxy nucleoside
 alt_id: CHEBI:14116;   CHEBI:19244;   CHEBI:23624;   CHEBI:42667;   CHEBI:42867;   CHEBI:42987;   CHEBI:4412
 xref: CAS:961-07-9;   HMDB:HMDB0000085;   KEGG:C00330
 xref_mesh: MESH:D003849
 xref: MetaCyc:DEOXYGUANOSINE;   PDBeChem:GNG;   Reaxys:39814;   Wikipedia:Deoxyguanosine


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2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP3A4 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    chemical entity 20843
      atom 20843
        nonmetal atom 20751
          carbon atom 20693
            organic molecular entity 20693
              purines 2'-deoxy-D-ribonucleoside 14
                2'-deoxyguanosine 6
                  6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                  8,5'-cyclo-2'-deoxyguanosine 0
                  N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                  N(2)-carboxyethyl-2'-deoxyguanosine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      carbon group element atom 20699
                        carbon atom 20693
                          organic molecular entity 20693
                            heteroorganic entity 20202
                              organochalcogen compound 19890
                                organooxygen compound 19792
                                  carbohydrates and carbohydrate derivatives 15420
                                    carbohydrate 15420
                                      carbohydrate derivative 14439
                                        glycosyl compound 13146
                                          N-glycosyl compound 5895
                                            nucleoside 5749
                                              deoxyribonucleoside 2896
                                                2'-deoxyribonucleoside 2251
                                                  purine 2'-deoxyribonucleoside 34
                                                    purines 2'-deoxy-D-ribonucleoside 14
                                                      2'-deoxyguanosine 6
                                                        6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                                                        8,5'-cyclo-2'-deoxyguanosine 0
                                                        N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                                                        N(2)-carboxyethyl-2'-deoxyguanosine + 0
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