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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2'-deoxyguanosine
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Accession:CHEBI:17172 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside having guanine as the nucleobase.
Synonyms:related_synonym: 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-9H-purin-6-ol;   9-(2-deoxy-beta-D-erythro-pentofuranosyl)-guanine;   Deoxyguanosine;   Formula=C10H13N5O4;   InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1;   InChIKey=YKBGVTZYEHREMT-KVQBGUIXSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1;   dG;   guanine deoxy nucleoside
 alt_id: CHEBI:14116;   CHEBI:19244;   CHEBI:23624;   CHEBI:42667;   CHEBI:42867;   CHEBI:42987;   CHEBI:4412
 xref: CAS:961-07-9;   HMDB:HMDB0000085;   KEGG:C00330
 xref_mesh: MESH:D003849
 xref: MetaCyc:DEOXYGUANOSINE;   PDBeChem:GNG;   Reaxys:39814;   Wikipedia:Deoxyguanosine



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2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP3A4 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          carbon atom 19609
            organic molecular entity 19609
              purines 2'-deoxy-D-ribonucleoside 14
                2'-deoxyguanosine 6
                  6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                  8,5'-cyclo-2'-deoxyguanosine 0
                  N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                  N(2)-carboxyethyl-2'-deoxyguanosine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  carbohydrates and carbohydrate derivatives 12342
                                    carbohydrate 12342
                                      carbohydrate derivative 11946
                                        glycosyl compound 10983
                                          N-glycosyl compound 5520
                                            nucleoside 5381
                                              deoxyribonucleoside 2739
                                                2'-deoxyribonucleoside 2221
                                                  purine 2'-deoxyribonucleoside 33
                                                    purines 2'-deoxy-D-ribonucleoside 14
                                                      2'-deoxyguanosine 6
                                                        6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                                                        8,5'-cyclo-2'-deoxyguanosine 0
                                                        N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                                                        N(2)-carboxyethyl-2'-deoxyguanosine + 0
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