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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2'-deoxyguanosine
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Accession:CHEBI:17172 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside having guanine as the nucleobase.
Synonyms:related_synonym: 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-9H-purin-6-ol;   9-(2-deoxy-beta-D-erythro-pentofuranosyl)-guanine;   Deoxyguanosine;   Formula=C10H13N5O4;   InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6+/m0/s1;   InChIKey=YKBGVTZYEHREMT-KVQBGUIXSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](CO)O1;   dG;   guanine deoxy nucleoside
 alt_id: CHEBI:14116;   CHEBI:19244;   CHEBI:23624;   CHEBI:42667;   CHEBI:42867;   CHEBI:42987;   CHEBI:4412
 xref: CAS:961-07-9;   HMDB:HMDB0000085;   KEGG:C00330
 xref_mesh: MESH:D003849
 xref: MetaCyc:DEOXYGUANOSINE;   PDBeChem:GNG;   Reaxys:39814;   Wikipedia:Deoxyguanosine


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2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556, PMID:9403342 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          carbon atom 19597
            organic molecular entity 19597
              purines 2'-deoxy-D-ribonucleoside 13
                2'-deoxyguanosine 5
                  6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                  8,5'-cyclo-2'-deoxyguanosine 0
                  N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                  N(2)-carboxyethyl-2'-deoxyguanosine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            heteroorganic entity 19184
                              organochalcogen compound 18894
                                organooxygen compound 18816
                                  carbohydrates and carbohydrate derivatives 12191
                                    carbohydrate 12191
                                      carbohydrate derivative 11814
                                        glycosyl compound 10856
                                          N-glycosyl compound 5340
                                            nucleoside 5200
                                              deoxyribonucleoside 2728
                                                2'-deoxyribonucleoside 2210
                                                  purine 2'-deoxyribonucleoside 32
                                                    purines 2'-deoxy-D-ribonucleoside 13
                                                      2'-deoxyguanosine 5
                                                        6-O-benzyl-2'-deoxyguanosine 5'-monophosphate 0
                                                        8,5'-cyclo-2'-deoxyguanosine 0
                                                        N(2)-(ADP-D-ribosyl)-2'-deoxyguanosine(2-) 0
                                                        N(2)-carboxyethyl-2'-deoxyguanosine + 0
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