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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:antiamoebic agent
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Accession:CHEBI:171664 term browser browse the term
Definition:An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
Synonyms:related_synonym: amebicide;   amebicides;   amoebicide;   amoebicides;   anti-amoebic agent;   anti-amoebic agents;   anti-amoebic drug;   anti-amoebic drugs;   antiamoebic;   antiamoebic agents;   antiamoebic drug;   antiamoebic drugs;   antiamoebics


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amphotericin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Amphotericin B results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer] CTD PMID:16189267 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Atg3 autophagy related 3 decreases expression ISO Amphotericin B results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224 		JBrowse link
G Casp3 caspase 3 increases expression ISO Amphotericin B results in increased expression of CASP3 protein CTD PMID:23988732 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases expression EXP Amphotericin B results in decreased expression of CAT mRNA CTD PMID:20623750 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression EXP Amphotericin B results in decreased expression of CCR2 mRNA CTD PMID:20623750 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Clu clusterin affects expression EXP Amphotericin B affects the expression of CLU mRNA CTD PMID:20623750 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Amphotericin B results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Eno1 enolase 1 multiple interactions ISO Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of ENO1 mRNA]; Amphotericin B results in increased expression of and results in increased secretion of ENO1 protein CTD PMID:16189267 PMID:26259607 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:16189267 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epo erythropoietin multiple interactions
decreases expression		 ISO
EXP		 Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]
Amphotericin B results in decreased expression of EPO protein		 CTD PMID:697352 PMID:2299214 PMID:16189267 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression ISO Amphotericin B results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898 		JBrowse link
G Gpr20 G protein-coupled receptor 20 increases expression ISO Amphotericin B results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:105,602,368...105,603,430 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
multiple interactions		 EXP
ISO		 Amphotericin B results in decreased expression of GSTP1 mRNA
Amphotericin B inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]		 CTD PMID:20623750 PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression EXP Amphotericin B results in decreased expression of GSTT1 mRNA CTD PMID:20623750 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases activity		 ISO Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]; Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]
Amphotericin B results in decreased activity of HIF1A protein		 CTD PMID:16189267 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor multiple interactions ISO Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein] CTD PMID:16189267 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO Amphotericin B results in increased expression of and results in increased secretion of HSPA8 protein CTD PMID:26259607 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein CTD PMID:17911647 PMID:29594315 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Amphotericin B results in increased expression of IFNGR1 CTD PMID:12803856 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Amphotericin B results in decreased expression of IGFBP5 mRNA CTD PMID:20849824 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein CTD PMID:17911647 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Amphotericin B results in increased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 decreases expression ISO Amphotericin B results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932 		JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 decreases expression ISO Amphotericin B results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr11:70,132,919...70,168,526
Ensembl chr11:70,143,847...70,168,518 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Amphotericin B results in increased expression of MAP1LC3B protein CTD PMID:23988732 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit decreases expression ISO Amphotericin B results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996 		JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO Amphotericin B results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO Amphotericin B results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr 2:51,523,142...51,550,241
Ensembl chr 2:51,522,921...51,550,241 		JBrowse link
G Pard3 par-3 family cell polarity regulator decreases expression ISO Amphotericin B results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA] CTD PMID:16189267 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Polm DNA polymerase mu increases expression ISO Amphotericin B results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Amphotericin B results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Runx3 RUNX family transcription factor 3 decreases expression ISO Amphotericin B results in decreased expression of RUNX3 mRNA CTD PMID:20849824 NCBI chr 5:147,393,926...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Slit1 slit guidance ligand 1 decreases expression ISO Amphotericin B results in decreased expression of SLIT1 mRNA CTD PMID:20849824 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression EXP Amphotericin B affects the expression of SPP1 mRNA CTD PMID:20623750 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein CTD PMID:17911647 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression ISO Amphotericin B results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715 		JBrowse link
G Tnf tumor necrosis factor increases expression EXP Amphotericin B results in increased expression of TNF mRNA CTD PMID:20623750 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects expression EXP Amphotericin B affects the expression of UGT1A9 mRNA CTD PMID:20623750 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Amphotericin B results in increased expression of USP36 mRNA CTD PMID:20849824 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877 		JBrowse link
amphotericin B methyl ester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO methylamphotericin B results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO methylamphotericin B results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO methylamphotericin B results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO methylamphotericin B results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
emetine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago3 argonaute RISC catalytic component 3 multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] CTD PMID:29576526 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230 		JBrowse link
G Akap9 A-kinase anchoring protein 9 multiple interactions ISO Emetine inhibits the reaction [sodium arsenite affects the localization of AKAP9 protein] CTD PMID:19073175 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606 		JBrowse link
G Ar androgen receptor multiple interactions ISO Emetine binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA] CTD PMID:29576526 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO Emetine inhibits the reaction [sodium arsenite affects the localization of CAPRIN1 protein] CTD PMID:19073175 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502 		JBrowse link
G Casp3 caspase 3 increases activity ISO Emetine results in increased activity of CASP3 protein CTD PMID:14502240 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO Emetine results in increased activity of CASP9 protein CTD PMID:14502240 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions ISO Emetine inhibits the reaction [sodium arsenite affects the localization of CCAR1 protein] CTD PMID:19073175 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Emetine results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Emetine results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Emetine results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Emetine results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA] CTD PMID:29576526 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Emetine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Emetine binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Emetine results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation		 ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK1 protein]
MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK1 protein]		 CTD PMID:15772366 PMID:26332055 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Emetine results in increased phosphorylation of and results in increased activity of MAPK14 protein; MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP2 protein]; MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP9 protein]; MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK1 protein]; MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK3 protein] CTD PMID:16364386 PMID:26332055 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases phosphorylation
multiple interactions		 ISO Emetine results in increased phosphorylation of MAPK3 protein
Emetine results in decreased phosphorylation of MAPK3 protein
MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK3 protein]
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK3 protein]		 CTD PMID:15772366 PMID:26332055 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 ISO 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK9 protein] CTD PMID:15772366 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Emetine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
multiple interactions
decreases expression		 ISO Emetine results in decreased activity of MMP2 protein
MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP2 protein]
Emetine results in decreased expression of MMP2 mRNA		 CTD PMID:26332055 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
multiple interactions
decreases expression		 ISO Emetine results in decreased activity of MMP9 protein
MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP9 protein]
Emetine results in decreased expression of MMP9 mRNA		 CTD PMID:26332055 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Emetine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Emetine results in increased cleavage of PARP1 protein CTD PMID:21256112 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Emetine binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs decreases expression ISO Emetine results in decreased expression of RECK mRNA CTD PMID:26332055 NCBI chr 5:58,102,915...58,169,513
Ensembl chr 5:58,102,981...58,169,502 		JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of RICTOR mRNA] CTD PMID:29576526 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426 		JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO Emetine affects the reaction [TARDBP protein binds to TIA1 protein]; Emetine affects the reaction [TARDBP protein binds to TIAR protein] CTD PMID:19765185 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO Emetine results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Emetine binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Emetine binds to and results in decreased activity of THRB protein CTD PMID:25752796 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein multiple interactions ISO Emetine affects the reaction [TARDBP protein binds to TIA1 protein] CTD PMID:19765185 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586 		JBrowse link
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 multiple interactions ISO Emetine affects the reaction [TARDBP protein binds to TIAR protein] CTD PMID:19765185 NCBI chr 1:183,008,358...183,045,092
Ensembl chr 1:183,009,253...183,031,637 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Emetine results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO Emetine inhibits the reaction [Thapsigargin affects the localization of XIAP mRNA] CTD PMID:29576526 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
iodoquinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Iodoquinol inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
metronidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Metronidazole results in decreased expression of ABCC2 mRNA CTD PMID:24657338 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO Metronidazole results in increased expression of ABCC3 mRNA CTD PMID:24657338 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Metronidazole results in increased expression of ABCG8 mRNA CTD PMID:24657338 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2 protein CTD PMID:30545405 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acat2l1 acetyl-CoA acetyltransferase 2-like 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2L1 protein CTD PMID:30545405 NCBI chr 1:47,803,822...47,829,012
Ensembl chr 1:47,803,813...47,829,151 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACE2 protein CTD PMID:30545405 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of AHSG protein CTD PMID:30545405 NCBI chr11:78,117,903...78,145,956 JBrowse link
G Aldoa aldolase, fructose-bisphosphate A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOA protein CTD PMID:30545405 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOB protein CTD PMID:30545405 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Arg2 arginase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ARPC3 protein CTD PMID:30545405 NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ASAH1 protein CTD PMID:30545405 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP1A1 protein CTD PMID:30545405 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein CTD PMID:30545405 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5J2 protein CTD PMID:30545405 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5H protein CTD PMID:30545405 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5J protein CTD PMID:30545405 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of B3GALT5 protein CTD PMID:30545405 NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917 		JBrowse link
G Clca4 chloride channel accessory 4 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLCA4 protein CTD PMID:30545405 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089 		JBrowse link
G Cldn7 claudin 7 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLDN7 protein CTD PMID:30545405 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CMBL protein CTD PMID:30545405 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009 		JBrowse link
G Cndp2 carnosine dipeptidase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CNDP2 protein CTD PMID:30545405 NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX5A protein CTD PMID:30545405 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX6B1 protein CTD PMID:30545405 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX7A2 protein CTD PMID:30545405 NCBI chr 8:80,716,824...80,720,922 JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of CSF2 protein CTD PMID:31442584 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctsa cathepsin A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CTSA protein CTD PMID:30545405 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2D2 mRNA CTD PMID:30545405 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO		 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP3A2 mRNA
Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Amiodarone]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Tacrolimus]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]		 CTD PMID:15855244 PMID:15869686 PMID:19299527 PMID:30545405 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EPCAM protein CTD PMID:30545405 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ereg epiregulin increases expression ISO Metronidazole results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ETFA protein CTD PMID:30545405 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969 		JBrowse link
G Ezr ezrin multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EZR protein CTD PMID:30545405 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GFPT2 protein CTD PMID:30545405 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329 		JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GIPC2 protein CTD PMID:30545405 NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236 		JBrowse link
G Gng12 G protein subunit gamma 12 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GNG12 protein CTD PMID:30545405 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GPX1 protein CTD PMID:30545405 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTA3 mRNA CTD PMID:30545405 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTM2 mRNA CTD PMID:30545405 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of HEXB protein CTD PMID:30545405 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HNRNPH2 protein CTD PMID:30545405 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041 		JBrowse link
G Hp haptoglobin multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HP protein CTD PMID:30545405 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Il24 interleukin 24 increases expression ISO Metronidazole results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein] CTD PMID:31442584 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kng2 kininogen 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAP1 protein CTD PMID:30545405 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Krt16 keratin 16 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of KRT16 protein CTD PMID:30545405 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Lyz2 lysozyme 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of LYZ2 protein CTD PMID:30545405 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAPK3 protein CTD PMID:30545405 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Myh14 myosin heavy chain 14 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MYH14 protein CTD PMID:30545405 NCBI chr 1:95,096,266...95,158,861
Ensembl chr 1:95,096,266...95,158,836 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFA13 protein CTD PMID:30545405 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFAB1 protein CTD PMID:30545405 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Metronidazole inhibits the reaction [Indomethacin results in increased activity of NOS2 protein] CTD PMID:12568917 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of NPC2 protein CTD PMID:30545405 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155 		JBrowse link
G Pfn1 profilin 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PFN1 protein CTD PMID:30545405 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein CTD PMID:30545405 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Pmm2 phosphomannomutase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PMM2 protein CTD PMID:30545405 NCBI chr10:6,961,521...6,982,913
Ensembl chr10:6,961,709...6,983,098 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CA protein CTD PMID:30545405 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CB protein CTD PMID:30545405 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CC protein CTD PMID:30545405 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein CTD PMID:30545405 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965 		JBrowse link
G Ralb RAS like proto-oncogene B multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RALB protein CTD PMID:30545405 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202 		JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276 		JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PDXK protein CTD PMID:30545405 NCBI chr20:10,162,934...10,192,610 JBrowse link
G Rida reactive intermediate imine deaminase A homolog multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RIDA protein CTD PMID:30545405 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716 		JBrowse link
G Rpl30 ribosomal protein L30 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPL30 protein CTD PMID:30545405 NCBI chr 7:65,648,470...65,651,363
Ensembl chr 7:65,645,991...65,651,363 		JBrowse link
G Rpn2 ribophorin II multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPN2 protein CTD PMID:30545405 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543 		JBrowse link
G Rps23 ribosomal protein S23 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS23 protein CTD PMID:30545405 NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918 		JBrowse link
G Rps27l ribosomal protein S27-like multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS27L protein CTD PMID:30545405 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Metronidazole affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 affects expression ISO Metronidazole affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G RT1-DMb RT1 class II, locus DMb multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RT1-DMB protein CTD PMID:30545405 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340 		JBrowse link
G S100a10 S100 calcium binding protein A10 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A10 protein CTD PMID:30545405 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A11 protein CTD PMID:30545405 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044 		JBrowse link
G Scarb2 scavenger receptor class B, member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of SCARB2 protein CTD PMID:30545405 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813 		JBrowse link
G Serpinb6a serpin family B member 6A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SERPINB6 protein CTD PMID:30545405 NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SHMT2 protein CTD PMID:30545405 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Slc3a1 solute carrier family 3 member 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SLC3A1 protein CTD PMID:30545405 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907 		JBrowse link
G Slc51b solute carrier family 51 subunit beta decreases expression ISO Metronidazole results in decreased expression of SLC51B mRNA CTD PMID:24657338 NCBI chr 8:65,931,891...65,934,893
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO Metronidazole results in increased expression of SLCO2B1 mRNA CTD PMID:24657338 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SMPD2 protein CTD PMID:30545405 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Tars1 threonyl-tRNA synthetase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TARS protein CTD PMID:30545405 NCBI chr 2:60,368,251...60,387,733
Ensembl chr 2:60,367,796...60,387,717 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TM9SF2 protein CTD PMID:30545405 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TMED10 protein CTD PMID:30545405 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein] CTD PMID:31442584 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tubal3 tubulin, alpha-like 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TUBAL3 protein CTD PMID:30545405 NCBI chr17:66,323,733...66,332,423
Ensembl chr17:66,323,733...66,335,355 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TWF1 protein CTD PMID:30545405 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Txndc5 thioredoxin domain containing 5 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TXNDC5 protein CTD PMID:30545405 NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRC1 protein CTD PMID:30545405 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRFS1 protein CTD PMID:30545405 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479 		JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRH protein CTD PMID:30545405 NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242 		JBrowse link
ornidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plau plasminogen activator, urokinase decreases expression EXP Ornidazole results in decreased expression of PLAU mRNA; Ornidazole results in decreased expression of PLAU protein CTD PMID:18998460 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
rifampicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase multiple interactions
increases hydrolysis
decreases acetylation		 ISO AADAC mRNA affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Isoflurophate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Phenylmethylsulfonyl Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Sodium Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]
AADAC protein results in increased hydrolysis of Rifampin		 CTD PMID:21856291 PMID:22207054 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression
increases expression		 ISO Rifampin results in decreased expression of ABCA1 mRNA; Rifampin results in decreased expression of ABCA1 protein
Rifampin results in increased expression of ABCA1 mRNA; Rifampin results in increased expression of ABCA1 protein		 CTD PMID:15883047 PMID:17088262 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca2 ATP binding cassette subfamily A member 2 increases expression ISO Rifampin results in increased expression of ABCA2 mRNA CTD PMID:27199754 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 decreases expression ISO Rifampin results in decreased expression of ABCA8 mRNA CTD PMID:27199754 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression
decreases activity
multiple interactions		 ISO
EXP		 Rifampin results in decreased expression of ABCB11 mRNA
Rifampin results in decreased activity of ABCB11 protein
Rifampin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]		 CTD PMID:12135489 PMID:16837569 PMID:20829430 PMID:24014644 PMID:28437613 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
decreases activity
affects activity		 ISO
EXP		 [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]; Rifampin promotes the reaction [NR1I2 protein binds to ABCB1 promoter]
Rifampin results in increased expression of ABCB1 mRNA; Rifampin results in increased expression of ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate
Rifampin affects the activity of ABCB1 protein		 CTD PMID:8632764 PMID:11744607 PMID:14722322 PMID:15276086 PMID:15290871 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Rifampin results in increased expression of ABCB4 mRNA CTD PMID:27199754 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Rifampin results in increased expression of ABCB6 mRNA CTD PMID:27199754 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Rifampin results in increased expression of ABCC1 mRNA CTD PMID:17191263 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 increases expression ISO Rifampin results in increased expression of ABCC10 mRNA CTD PMID:27199754 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
increases expression
multiple interactions		 ISO ABCC2 protein affects the export of Rifampin
Rifampin results in increased expression of ABCC2; Rifampin results in increased expression of ABCC2 mRNA; Rifampin results in increased expression of ABCC2 protein
[Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein		 CTD PMID:11836020 PMID:12206135 PMID:15652233 PMID:16837569 PMID:16952291 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
increases activity		 ISO [Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; Rifampin inhibits the reaction [Decitabine results in increased expression of ABCC3 mRNA]
Rifampin results in increased expression of ABCC3 mRNA
Rifampin results in increased activity of ABCC3 protein		 CTD PMID:14570758 PMID:16837569 PMID:16952291 PMID:19041851 PMID:20832446 More... NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Rifampin results in increased expression of ABCC5 mRNA CTD PMID:19041851 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 increases expression ISO Rifampin results in increased expression of ABCC6 mRNA CTD PMID:27199754 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 increases expression ISO Rifampin results in increased expression of ABCF1 mRNA CTD PMID:27199754 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Rifampin results in increased expression of ABCG1 mRNA; Rifampin results in increased expression of ABCG1 protein CTD PMID:12040753 PMID:17088262 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Rifampin results in increased expression of ABCG2 mRNA CTD PMID:16837569 PMID:27199754 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Rifampin results in increased expression of ABCG8 mRNA CTD PMID:27199754 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Abi3 ABI family, member 3 decreases expression ISO Rifampin results in decreased expression of ABI3 mRNA CTD PMID:24552687 NCBI chr10:80,769,819...80,780,816
Ensembl chr10:80,769,822...80,780,816 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO Rifampin results in increased expression of ACACA mRNA CTD PMID:27806127 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO Rifampin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Actr10 actin related protein 10 increases expression ISO Rifampin results in increased expression of ACTR10 mRNA CTD PMID:24552687 NCBI chr 6:89,446,141...89,472,350
Ensembl chr 6:89,446,093...89,473,047 		JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Rifampin results in increased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Rifampin results in decreased expression of ADORA2A mRNA CTD PMID:24552687 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 decreases expression ISO Rifampin results in decreased expression of AGAP2 mRNA CTD PMID:24552687 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression		 ISO [Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in decreased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of AHR protein; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]
Rifampin results in increased expression of AHR mRNA; Rifampin results in increased expression of AHR protein		 CTD PMID:22733800 PMID:28428138 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression
multiple interactions		 ISO Rifampin results in increased expression of AKR1B10 mRNA
pazopanib inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA]		 CTD PMID:29356861 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Rifampin results in increased expression of ALAS1 mRNA CTD PMID:24259679 PMID:24552687 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Rifampin results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA CTD PMID:21127053 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankrd65 ankyrin repeat domain 65 decreases expression ISO Rifampin results in decreased expression of ANKRD65 mRNA CTD PMID:24552687 NCBI chr 5:166,398,359...166,400,616
Ensembl chr 5:166,397,748...166,400,953 		JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Rifampin results in decreased expression of ANKS1B mRNA CTD PMID:24552687 NCBI chr 7:24,313,810...25,479,307
Ensembl chr 7:24,312,843...25,477,693 		JBrowse link
G Anxa5 annexin A5 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA CTD PMID:21224054 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apob apolipoprotein B decreases expression
multiple interactions
affects secretion		 ISO Rifampin results in decreased expression of APOB mRNA
ursodoxicoltaurine inhibits the reaction [Rifampin results in decreased expression of APOB mRNA]
Rifampin affects the secretion of APOB protein		 CTD PMID:32535746 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression
decreases secretion		 ISO Rifampin results in decreased expression of APOC3 mRNA
Rifampin results in decreased secretion of APOC3 protein		 CTD PMID:32535746 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA CTD PMID:21127053 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO Rifampin results in decreased expression of AQP4 mRNA CTD PMID:24552687 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Arsj arylsulfatase family, member J decreases expression ISO Rifampin results in decreased expression of ARSJ mRNA CTD PMID:24552687 NCBI chr 2:214,775,483...214,853,655 JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Rifampin co-treated with Cobicistat] results in increased expression of ATF3 mRNA CTD PMID:33629115 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression		 EXP
ISO		 ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
Rifampin results in increased expression of ATF4 mRNA; Rifampin results in increased expression of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 protein]		 CTD PMID:24638036 PMID:27470132 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Rifampin results in increased expression of ATF6 mRNA CTD PMID:32535746 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
decreases expression		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein
Rifampin results in decreased expression of ATM mRNA		 CTD PMID:21224054 PMID:24552687 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression
multiple interactions		 ISO Rifampin results in increased expression of ATP6V0A1 protein
[Rotenone co-treated with Rifampin] results in increased expression of ATP6V0A1 protein; Rifampin inhibits the reaction [Rotenone results in decreased expression of ATP6V0A1 mRNA]; Rotenone inhibits the reaction [Rifampin results in increased expression of ATP6V0A1 protein]		 CTD PMID:31648047 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 multiple interactions ISO ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]] CTD PMID:31648047 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Rifampin results in increased expression of ATRX mRNA CTD PMID:24552687 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression		 ISO [Isoniazid co-treated with Rifampin] results in increased expression of BAX protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of BAX mRNA; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein]
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein
Rifampin results in decreased expression of BAX protein		 CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:21419764 PMID:31629065 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions		 ISO Rifampin results in increased expression of BCL2 protein
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein
[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein]		 CTD PMID:11958592 PMID:21419764 PMID:31629065 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions		 ISO Rifampin results in increased expression of BCL2L1 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA		 CTD PMID:11958592 PMID:12645856 PMID:21224054 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA CTD PMID:21127053 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA CTD PMID:21127053 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Car1 carbonic anhydrase 1 decreases expression ISO Rifampin results in decreased expression of CA1 mRNA CTD PMID:24552687 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO Rifampin inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein] CTD PMID:26086368 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [Staurosporine results in increased cleavage of CASP3 protein]; Rifampin promotes the reaction [Galactosamine results in increased activity of CASP3 protein]
[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]		 CTD PMID:11958592 PMID:12645856 PMID:17936189 PMID:21419764 PMID:23764483 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:11958592 PMID:12645856 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cbr3 carbonyl reductase 3 multiple interactions ISO [Rifampin co-treated with Cobicistat] results in increased expression of CBR3 mRNA CTD PMID:33629115 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Rifampin results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression EXP Rifampin results in decreased expression of CCL5 protein CTD PMID:25051504 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA CTD PMID:21127053 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA CTD PMID:21224054 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA CTD PMID:21224054 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA CTD PMID:21127053 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA CTD PMID:21127053 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309 		JBrowse link
G Cd36 CD36 molecule increases expression ISO Rifampin results in increased expression of CD36 mRNA CTD PMID:27806127 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA CTD PMID:21127053 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Rifampin results in increased expression of CES1 protein CTD PMID:10640517 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions		 ISO Rifampin results in increased expression of CES2 mRNA; Rifampin results in increased expression of CES2 protein
Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]		 CTD PMID:10640517 PMID:17003103 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression		 ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]
Rifampin results in increased expression of CFLAR protein		 CTD PMID:11958592 PMID:12645856 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA CTD PMID:21224054 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 decreases expression ISO Rifampin results in decreased expression of CIZ1 mRNA CTD PMID:24552687 NCBI chr 3:15,658,479...15,675,716
Ensembl chr 3:15,658,539...15,673,762 		JBrowse link
G Cntln centlein increases expression ISO Rifampin results in increased expression of CNTLN mRNA CTD PMID:24552687 NCBI chr 5:99,295,865...99,576,402
Ensembl chr 5:99,296,000...99,576,396 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Rifampin results in increased expression of CPT1A mRNA CTD PMID:27806127 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 decreases expression ISO Rifampin results in decreased expression of CRHR1 mRNA CTD PMID:24552687 NCBI chr10:89,040,203...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crp C-reactive protein multiple interactions ISO [Floxacillin co-treated with Gentamicins co-treated with Rifampin] results in increased expression of CRP protein CTD PMID:16943303 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 decreases expression ISO Rifampin results in decreased expression of CSNK1G1 mRNA CTD PMID:24552687 NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Rifampin results in increased expression of CXCL1 protein CTD PMID:25051504 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
affects expression		 ISO
EXP		 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA
Rifampin affects the expression of CXCL10 protein		 CTD PMID:21224054 PMID:25051504 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cyb5rl cytochrome b5 reductase-like increases expression ISO Rifampin results in increased expression of CYB5RL mRNA CTD PMID:24552687 NCBI chr 5:121,846,223...121,868,287
Ensembl chr 5:121,847,952...121,868,745 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression		 EXP
ISO		 Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Rifampin results in increased activity of CYP1A1 protein
Rifampin results in increased expression of CYP1A1 mRNA; Rifampin results in increased expression of CYP1A1 protein
[Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP1A1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 protein; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A1 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]		 CTD PMID:12040753 PMID:18493746 PMID:19118567 PMID:19409404 PMID:22733800 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression		 ISO
EXP		 [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Rifampin results in increased expression of CYP1A2 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein
Rifampin results in increased expression of CYP1A2 mRNA; Rifampin results in increased expression of CYP1A2 protein		 CTD PMID:15977188 PMID:17590308 PMID:18493746 PMID:25835148 PMID:29162470 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1B1 mRNA		 CTD PMID:21224054 PMID:29162470 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity		 ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]
Rifampin results in increased activity of CYP24A1 protein		 CTD PMID:15630458 PMID:21127053 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA CTD PMID:21127053 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression		 ISO Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]
Rifampin results in increased expression of CYP27A1 mRNA		 CTD PMID:17088262 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Rifampin results in increased expression of CYP2A1 mRNA CTD PMID:19118567 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions
increases expression
increases activity		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA
Rifampin results in increased expression of CYP2A5 mRNA
Rifampin results in increased activity of CYP2A5 protein		 CTD PMID:11038160 PMID:21224054 PMID:30503582 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression		 ISO [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA
Rifampin results in increased expression of CYP2B10 mRNA		 CTD PMID:21224054 PMID:25835148 PMID:30503582 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression
increases expression
increases activity		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA
Rifampin results in decreased expression of CYP2B9 mRNA
Rifampin results in increased expression of CYP2B6 mRNA; Rifampin results in increased expression of CYP2B6 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2B6 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Dexamethasone promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; GW 3965 inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP2B6 protein
Rifampin results in increased activity of CYP2B6 protein		 CTD PMID:12040753 PMID:12571232 PMID:12695351 PMID:14709624 PMID:14977870 More... NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases expression ISO Rifampin results in decreased expression of CYP2C18 mRNA; Rifampin results in decreased expression of CYP2C18 protein CTD PMID:22258563 PMID:31629065 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases activity
increases expression
multiple interactions		 ISO Rifampin results in increased activity of CYP2C19 protein
Rifampin results in increased expression of CYP2C19 mRNA; Rifampin results in increased expression of CYP2C19 protein
Rifampin results in increased expression of and results in increased activity of CYP2C19 protein		 CTD PMID:12584154 PMID:14709624 PMID:15629111 PMID:17954527 PMID:19118567 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 affects binding
increases expression
multiple interactions
increases activity		 ISO [Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter
Rifampin results in increased expression of CYP2C29 mRNA
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein
Rifampin results in increased expression of CYP2C8 mRNA; Rifampin results in increased expression of CYP2C8 protein
Rifampin results in increased activity of CYP2C8 protein		 CTD PMID:12040753 PMID:15771232 PMID:15933212 PMID:17954527 PMID:19118567 More...
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression
decreases expression		 ISO Rifampin results in increased expression of CYP2D6 mRNA
Rifampin results in decreased expression of CYP2D22 mRNA		 CTD PMID:19041851 PMID:30503582 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
decreases expression
multiple interactions
increases expression		 ISO
EXP		 Rifampin results in increased activity of CYP2E1 protein
Rifampin results in decreased expression of CYP2E1 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein
Rifampin results in increased expression of CYP2E1 mRNA; Rifampin results in increased expression of CYP2E1 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein; [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]		 CTD PMID:15132840 PMID:18071298 PMID:22258563 PMID:22733800 PMID:25835148 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression ISO Rifampin results in decreased expression of CYP2F1 mRNA CTD PMID:22258563 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 decreases expression ISO Rifampin results in decreased expression of CYP2J2 mRNA CTD PMID:33263786 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA CTD PMID:21127053 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
affects activity
increases expression
decreases response to substance
increases activity		 EXP
ISO		 [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]; arsenite inhibits the reaction [Rifampin results in increased expression of and results in increased activity of CYP3A2 protein]; arsenite inhibits the reaction [Rifampin results in increased expression of CYP3A2 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP3A2 protein
Rifampin affects the activity of CYP3A4 protein
Rifampin results in increased expression of CYP3A4; Rifampin results in increased expression of CYP3A4 mRNA; Rifampin results in increased expression of CYP3A4 mRNA alternative form; Rifampin results in increased expression of CYP3A4 protein
[[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein] which results in increased metabolism of and results in increased activity of and results in increased susceptibility to Cobicistat; [Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA; [HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP3A4 mRNA; [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; [NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA; [PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP3A4 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP3A4 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin results in increased expression of CYP3A4 protein] which results in decreased abundance of Ethinyl Estradiol; [Rifampin results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; [Rifampin results in increased expression of CYP3A4 protein] which results in increased hydroxylation of Testosterone; [Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein; [RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; AADAC mRNA affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]; allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Arsenic Trioxide inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Calcitriol promotes the reaction [Rifampin results in increased activity of CYP3A4 protein]; Calcitriol promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased chemical synthesis of 1-hydroxymethylmidazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased chemical synthesis of 4-hydroxymidazolam]; CYP3A4 protein inhibits the reaction [Rifampin results in decreased hydroxylation of Midazolam]; Dexamethasone promotes the reaction [Rifampin results in increased activity of CYP3A4 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Econazole promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Galactosamine inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; GW 3965 inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; lorlatinib inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]; Metformin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Metformin inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR3C1 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; oxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]; periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Rifampin binds to and results in increased activity of CYP3A4 protein; Rifampin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased chemical synthesis of 4-hydroxymidazolam]; Rifampin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [Calcitriol results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [CYP3A4 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam]; Rifampin promotes the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Rifampin promotes the reaction [CYP3A4 protein results in increased metabolism of Lidocaine]; Rifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP3A4 protein; Skatole inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Skatole inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; sodium arsenite inhibits the reaction [Rifampin results in increased expression of and results in increased activity of CYP3A4 protein]; sodium arsenite inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; sulforaphane inhibits the reaction [Rifampin results in increased expression of CYP3A4]; Tetrachlorodibenzodioxin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]; Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; trichostatin A affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; trichostatin A promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
CYP3A4 protein results in decreased susceptibility to Rifampin
[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein; Rifampin results in increased activity of CYP3A4 protein
Rifampin results in increased expression of CYP3A2 mRNA; Rifampin results in increased expression of CYP3A4 mRNA		 CTD PMID:8632764 PMID:9298257 PMID:9512926 PMID:10219967 PMID:10640517 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression		 EXP [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA; arsenite inhibits the reaction [Rifampin results in increased expression of and results in increased activity of CYP3A23-3A1 protein]; arsenite inhibits the reaction [Rifampin results in increased expression of CYP3A23-3A1 mRNA]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin results in increased expression of and results in increased activity of CYP3A23-3A1 protein; sodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:12370413 PMID:19041297 PMID:22159698 PMID:22310326 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Rifampin results in increased expression of CYP3A5 mRNA CTD PMID:12040753 PMID:12673034 PMID:15629111 PMID:15681896 PMID:19118567 More... NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA
Rifampin results in decreased expression of CYP7A1 mRNA
NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]		 CTD PMID:15629111 PMID:21127053 PMID:21224054 PMID:22258563 PMID:24259679 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA CTD PMID:21127053 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 decreases expression ISO Rifampin results in decreased expression of DCAF5 mRNA CTD PMID:24552687 NCBI chr 6:99,171,506...99,260,183
Ensembl chr 6:99,171,506...99,260,110 		JBrowse link
G Dclre1b DNA cross-link repair 1B decreases expression ISO Rifampin results in decreased expression of DCLRE1B mRNA CTD PMID:24552687 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of DDIT3 mRNA
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of DDIT3 mRNA]
Rifampin results in increased expression of DDIT3 mRNA; Rifampin results in increased expression of DDIT3 protein		 CTD PMID:21224054 PMID:27470132 PMID:32535746 PMID:33629115 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA CTD PMID:22101211 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dio1 iodothyronine deiodinase 1 increases expression ISO Rifampin results in increased expression of DIO1 mRNA CTD PMID:24552687 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dlx4 distal-less homeobox 4 decreases expression ISO Rifampin results in decreased expression of DLX4 mRNA CTD PMID:24552687 NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,085,465...80,090,456 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA CTD PMID:21224054 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA CTD PMID:21127053 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA		 CTD PMID:21127053 PMID:21224054 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA CTD PMID:21127053 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr4 early growth response 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA CTD PMID:21127053 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression
multiple interactions		 EXP
ISO		 Rifampin results in increased phosphorylation of EIF2AK3 protein
Rifampin results in increased expression of EIF2AK3 mRNA; Rifampin results in increased expression of EIF2AK3 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 protein]		 CTD PMID:24638036 PMID:27470132 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Rifampin results in increased phosphorylation of EIF2S1 protein CTD PMID:24638036 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Elk1 ETS transcription factor ELK1 decreases expression ISO Rifampin results in decreased expression of ELK1 mRNA CTD PMID:24552687 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions		 ISO Rifampin results in increased expression of EPHX1 mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA]		 CTD PMID:22258563 PMID:25313206 PMID:29356861 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression		 ISO Rifampin results in increased expression of and results in increased phosphorylation of ERN1 protein
Rifampin results in increased expression of ERN1 mRNA		 CTD PMID:32535746 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase increases expression ISO Rifampin results in increased expression of ETNPPL mRNA CTD PMID:24552687 NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212 		JBrowse link
G F13b coagulation factor XIII B chain increases expression ISO Rifampin results in increased expression of F13B mRNA CTD PMID:24552687 NCBI chr13:51,130,851...51,156,383
Ensembl chr13:51,130,920...51,156,381 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein] CTD PMID:11958592 PMID:12645856 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions
decreases expression		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA
Rifampin results in decreased expression of FASLG mRNA; Rifampin results in decreased expression of FASLG protein
Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]		 CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:24552687 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions		 ISO Rifampin results in increased expression of FASN mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of FASN mRNA]		 CTD PMID:27806127 PMID:29356861 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions
increases expression		 ISO [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA
Rifampin results in increased expression of FGF19 mRNA		 CTD PMID:17696253 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA CTD PMID:21224054 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA CTD PMID:21224054 NCBI chr13:75,154,683...75,172,932
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Foxa1 forkhead box A1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA CTD PMID:21127053 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Rifampin results in increased expression of FOXP1 mRNA CTD PMID:24552687 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO Rifampin results in decreased expression of FUT1 mRNA CTD PMID:24552687 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
affects expression		 ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA] CTD PMID:24204015 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA CTD PMID:21224054 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA] CTD PMID:21127053 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gata5 GATA binding protein 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA CTD PMID:21127053 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Gck glucokinase decreases expression
multiple interactions		 ISO Rifampin results in decreased expression of GCK protein
NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]		 CTD PMID:26616219 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Rifampin results in increased expression of GLIS2 mRNA CTD PMID:24552687 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578 		JBrowse link
G Gnal G protein subunit alpha L decreases expression ISO Rifampin results in decreased expression of GNAL mRNA CTD PMID:24552687 NCBI chr18:60,622,311...60,762,599
Ensembl chr18:60,622,311...60,762,599 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression		 ISO 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of GPT protein]; [Rifampin co-treated with Acetaminophen] results in decreased activity of GPT protein
Rifampin inhibits the reaction [Acetaminophen results in increased expression of GPT protein]		 CTD PMID:24685772 PMID:27470132 PMID:31678598 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of GPX2 mRNA CTD PMID:21224054 PMID:33629115 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression ISO Rifampin results in decreased expression of GRIA1 mRNA CTD PMID:24552687 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity ISO Rifampin results in increased activity of GSR protein CTD PMID:20848779 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions
increases expression		 ISO [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of GSTA1 mRNA; Ketoconazole inhibits the reaction [Rifampin results in increased expression of GSTA1 mRNA] CTD PMID:16608920 PMID:19118567 PMID:29162470 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein CTD PMID:21224054 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA CTD PMID:21224054 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression		 ISO [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 protein
Rifampin results in increased expression of GSTP1 mRNA; Rifampin results in increased expression of GSTP1 protein		 CTD PMID:22733800 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions ISO GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin]; GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide] CTD PMID:18397238 PMID:20485159 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 increases expression ISO Rifampin results in increased expression of GTF2IRD2 mRNA CTD PMID:24552687 NCBI chr12:22,498,360...22,551,293
Ensembl chr12:22,498,091...22,536,263 		JBrowse link
G Gzmb granzyme B increases secretion ISO Rifampin results in increased secretion of GZMB protein CTD PMID:27933861 NCBI chr15:30,343,361...30,346,792 JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA CTD PMID:21127053 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA CTD PMID:21127053 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA CTD PMID:21127053 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species]; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] CTD PMID:23764483 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA CTD PMID:21127053 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 increases expression ISO Rifampin results in increased expression of HMGN5 mRNA CTD PMID:24552687 NCBI chr  X:74,085,871...74,094,488 JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 ISO
EXP		 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA
dorsomorphin inhibits the reaction [Rifampin results in increased expression of HMOX1 protein]
Rifampin results in increased expression of HMOX1 mRNA; Rifampin results in increased expression of HMOX1 protein
[arsenite co-treated with Rifampin] results in increased expression of HMOX1 mRNA		 CTD PMID:21224054 PMID:22159698 PMID:22258563 PMID:31678598 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha multiple interactions ISO [HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:21127053 PMID:21292004 PMID:21764778 PMID:25069801 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hrh1 histamine receptor H 1 increases expression ISO Rifampin results in increased expression of HRH1 mRNA CTD PMID:24552687 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA CTD PMID:21224054 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 EXP
ISO		 ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
[Rifampin co-treated with Cobicistat] results in increased expression of HSPA5 mRNA
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
Rifampin results in increased expression of HSPA5 mRNA; Rifampin results in increased expression of HSPA5 protein		 CTD PMID:24638036 PMID:27470132 PMID:32535746 PMID:33629115 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA CTD PMID:21224054 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA CTD PMID:21224054 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA CTD PMID:21224054 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Ifng interferon gamma increases secretion ISO Rifampin results in increased secretion of IFNG protein CTD PMID:27933861 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA CTD PMID:21127053 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA CTD PMID:21127053 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA CTD PMID:21127053 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Il10 interleukin 10 affects expression EXP Rifampin affects the expression of IL10 protein CTD PMID:25051504 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 decreases expression ISO Rifampin results in decreased expression of IL12RB2 mRNA CTD PMID:24552687 NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289 		JBrowse link
G Il13 interleukin 13 increases secretion ISO Rifampin results in increased secretion of IL13 protein CTD PMID:27933861 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO
EXP		 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; Rifampin inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Rifampin results in decreased expression of IL1B mRNA; Rifampin results in decreased expression of IL1B protein		 CTD PMID:21224054 PMID:25051504 PMID:26086368 PMID:31648047 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Rifampin results in decreased expression of IL6 protein
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]
Rifampin results in increased expression of IL6 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA		 CTD PMID:21224054 PMID:21357946 PMID:25051504 PMID:31648047 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ino80d INO80 complex subunit D decreases expression ISO Rifampin results in decreased expression of INO80D mRNA CTD PMID:24552687 NCBI chr 9:64,447,075...64,514,013
Ensembl chr 9:64,457,165...64,515,242 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA] CTD PMID:24204015 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO Rifampin results in decreased expression of INTS6 mRNA CTD PMID:24552687 NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527 		JBrowse link
G Iqca1 IQ motif containing with AAA domain 1 decreases expression ISO Rifampin results in decreased expression of IQCA1 mRNA CTD PMID:24552687 NCBI chr 9:90,626,735...90,742,563 JBrowse link
G Itgbl1 integrin subunit beta like 1 decreases expression ISO Rifampin results in decreased expression of ITGBL1 mRNA CTD PMID:24552687 NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA CTD PMID:21127053 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression ISO Rifampin results in decreased expression of KIRREL3 mRNA CTD PMID:24552687 NCBI chr 8:32,865,779...33,407,555
Ensembl chr 8:32,862,776...33,405,676 		JBrowse link
G Klf2 Kruppel-like factor 2 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA CTD PMID:21127053 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf5 Kruppel-like factor 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA CTD PMID:21127053 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA CTD PMID:21127053 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Rifampin results in increased expression of LDLR mRNA CTD PMID:27806127 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lefty1 left right determination factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA CTD PMID:21127053 NCBI chr13:92,649,226...92,659,722
Ensembl chr13:92,656,323...92,659,720 		JBrowse link
G Lep leptin increases expression EXP Rifampin results in increased expression of LEP protein CTD PMID:25051504 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G LOC100910107 ubiquitin carboxyl-terminal hydrolase DUB-1-like decreases expression ISO Rifampin results in decreased expression of USP17L2 mRNA CTD PMID:24552687 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G LOC100912252 uncharacterized LOC100912252 decreases expression ISO Rifampin results in decreased expression of C9ORF153 mRNA CTD PMID:24552687 NCBI chr17:4,974,540...4,982,400
Ensembl chr17:4,964,834...4,982,766 		JBrowse link
G LOC498933 LOC498933 decreases expression ISO Rifampin results in decreased expression of C4ORF51 mRNA CTD PMID:24552687 NCBI chr19:28,669,059...28,704,512
Ensembl chr19:28,669,059...28,704,508 		JBrowse link
G Ltk leukocyte receptor tyrosine kinase increases expression ISO Rifampin results in increased expression of LTK mRNA CTD PMID:24552687 NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369 		JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA CTD PMID:21127053 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases metabolic processing
multiple interactions
increases lipidation		 ISO Rifampin results in decreased metabolism of MAP1LC3B protein
ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]]; Chloroquine promotes the reaction [Rifampin results in increased lipidation of MAP1LC3B protein]; Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]		 CTD PMID:29908302 PMID:31648047 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]]; Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases phosphorylation ISO Rifampin results in increased phosphorylation of MAPKAPK2 protein CTD PMID:21127053 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 increases expression ISO Rifampin results in increased expression of MAPRE3 mRNA CTD PMID:24552687 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881 		JBrowse link
G Matn2 matrilin 2 increases expression ISO Rifampin results in increased expression of MATN2 mRNA CTD PMID:27177772 NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113 		JBrowse link
G Mbp myelin basic protein affects expression EXP Rifampin affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein CTD PMID:31629065 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA CTD PMID:21224054 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Med1 mediator complex subunit 1 multiple interactions
decreases expression		 ISO Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]
Rifampin results in decreased expression of MED1 mRNA		 CTD PMID:21292004 PMID:22214767 PMID:24552687 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Minpp1 multiple inositol-polyphosphate phosphatase 1 increases expression ISO Rifampin results in increased expression of MINPP1 mRNA CTD PMID:24552687 NCBI chr 1:230,354,483...230,379,730
Ensembl chr 1:230,354,438...230,379,730 		JBrowse link
G Mir143 microRNA 143 increases expression ISO Rifampin results in increased expression of MIR143 mRNA CTD PMID:24552687 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir145 microRNA 145 increases expression ISO Rifampin results in increased expression of MIR145 mRNA CTD PMID:24552687 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir148b microRNA 148b decreases expression ISO Rifampin results in decreased expression of MIR148B mRNA CTD PMID:24552687 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494 		JBrowse link
G Mir15b microRNA 15b increases expression ISO Rifampin results in increased expression of MIR15B mRNA CTD PMID:24552687 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir192 microRNA 192 decreases expression ISO Rifampin results in decreased expression of MIR192 mRNA CTD PMID:24552687 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
G Mir200a microRNA 200a increases expression ISO Rifampin results in increased expression of MIR200A mRNA CTD PMID:24552687 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir202 microRNA 202 increases expression ISO Rifampin results in increased expression of MIR202 mRNA CTD PMID:24552687 NCBI chr 1:194,754,730...194,754,801
Ensembl chr 1:194,754,730...194,754,801 		JBrowse link
G Mir204 microRNA 204 increases expression ISO Rifampin results in increased expression of MIR204 mRNA CTD PMID:24552687 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir20b microRNA 20b increases expression ISO Rifampin results in increased expression of MIR20B mRNA CTD PMID:24552687 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282 		JBrowse link
G Mir21 microRNA 21 increases expression ISO Rifampin results in increased expression of MIR21 mRNA CTD PMID:24552687 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir212 microRNA 212 decreases expression ISO Rifampin results in decreased expression of MIR212 mRNA CTD PMID:24552687 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir22 microRNA 22 increases expression ISO Rifampin results in increased expression of MIR22 mRNA CTD PMID:24552687 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir26b microRNA 26b increases expression ISO Rifampin results in increased expression of MIR26B mRNA CTD PMID:24552687 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680 		JBrowse link
G Mir296 microRNA 296 decreases expression ISO Rifampin results in decreased expression of MIR296 mRNA CTD PMID:24552687 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915 		JBrowse link
G Mir29a microRNA 29a decreases expression ISO Rifampin results in decreased expression of MIR29A mRNA CTD PMID:24552687 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir31 microRNA 31 increases expression ISO Rifampin results in increased expression of MIR31 mRNA CTD PMID:24552687 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir328 microRNA 328 increases expression ISO Rifampin results in increased expression of MIR328 mRNA CTD PMID:24552687 NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849 		JBrowse link
G Mir34a microRNA 34a decreases expression ISO Rifampin results in decreased expression of MIR34A mRNA CTD PMID:24552687 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir374b microRNA 374b increases expression ISO Rifampin results in increased expression of MIR374B mRNA CTD PMID:24552687 NCBI chr  X:68,591,732...68,591,799
Ensembl chr  X:68,591,732...68,591,799 		JBrowse link
G Mir532 microRNA 532 decreases expression ISO Rifampin results in decreased expression of MIR532 mRNA CTD PMID:24552687 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393 		JBrowse link
G Mir628 microRNA 628 decreases expression ISO Rifampin results in decreased expression of MIR628 mRNA CTD PMID:24552687 NCBI chr 8:73,739,846...73,739,929
Ensembl chr 8:73,739,846...73,739,929 		JBrowse link
G Mir652 microRNA 652 decreases expression ISO Rifampin results in decreased expression of MIR652 mRNA CTD PMID:24552687 NCBI chr  X:106,343,293...106,343,373
Ensembl chr  X:106,343,293...106,343,373 		JBrowse link
G Mir874 microRNA 874 decreases expression ISO Rifampin results in decreased expression of MIR874 mRNA CTD PMID:24552687 NCBI chr17:6,620,649...6,620,724
Ensembl chr17:6,620,649...6,620,724 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein CTD PMID:21224054 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases secretion ISO Rifampin results in decreased secretion of MMP3 protein CTD PMID:24890593 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:24101390 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Rifampin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO Rifampin results in decreased expression of MTTP mRNA CTD PMID:32535746 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO Rifampin results in increased expression of MYH6 mRNA CTD PMID:24552687 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein decreases expression ISO Rifampin results in decreased expression of NAF1 mRNA CTD PMID:24552687 NCBI chr16:22,837,586...22,868,293
Ensembl chr16:22,837,588...22,868,293 		JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 increases expression ISO Rifampin results in increased expression of NAP1L5 mRNA CTD PMID:24552687 NCBI chr 4:88,022,670...88,024,988
Ensembl chr 4:88,022,569...88,024,654 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Miconazole promotes the reaction [Rifampin results in increased expression of NCOA1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein] CTD PMID:11581012 PMID:12072427 PMID:16819505 PMID:17088262 PMID:17438109 More... NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 multiple interactions ISO NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein] CTD PMID:22214767 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein] CTD PMID:12072427 PMID:22214767 PMID:25313206 PMID:26883953 PMID:28289823 More... NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO Rifampin results in increased expression of NFE2L2 protein CTD PMID:31678598 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfya nuclear transcription factor Y subunit alpha decreases expression ISO Rifampin results in decreased expression of NFYA mRNA CTD PMID:24552687 NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Rifampin inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] CTD PMID:26086368 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA
Rifampin results in increased expression of NOS2 mRNA		 CTD PMID:21224054 PMID:24552687 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npas1 neuronal PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA CTD PMID:21127053 NCBI chr 1:77,167,375...77,187,887
Ensembl chr 1:77,167,381...77,186,762 		JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA CTD PMID:21127053 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Rifampin results in increased expression of NR0B2 mRNA CTD PMID:15670600 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO NR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:23732298 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
affects localization
decreases acetylation
increases response to substance
increases activity
decreases response to substance
multiple interactions
increases expression
increases localization
affects binding		 ISO
EXP		 NR1I2 protein affects the susceptibility to Rifampin
Rifampin affects the localization of NR1I2 protein
Rifampin results in decreased acetylation of NR1I2 protein
NR1I2 protein results in increased susceptibility to Rifampin
[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein; Rifampin results in increased activity of NR1I2 protein
NR1I2 protein mutant form results in decreased susceptibility to Rifampin
1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein] which results in increased metabolism of and results in increased activity of and results in increased susceptibility to Cobicistat; [fexofenadine co-treated with Rifampin] results in increased activity of NR1I2 protein; [Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein; [Loperamide co-treated with Rifampin] results in increased activity of NR1I2 protein; [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; [NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein; [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA; [Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Camptothecin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; caraway oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Clove Oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; coriander oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Doxorubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Epirubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Fluconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; hydroxyitraconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Itraconazole promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; jasmine oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; lemongrass oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Miconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Nelfinavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]; NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased abundance of Lipids]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Oils, Volatile inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Oils, Volatile promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; oxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]; oxiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pazopanib inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin binds to and results in increased activity of NR1I2 protein; Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin inhibits the reaction [oxiconazole results in increased expression of NR1I2 mRNA]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin inhibits the reaction [trichostatin A results in increased acetylation of NR1I2 protein]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to ABCB1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]; sodium arsenite inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; trichostatin A affects the reaction [Rifampin affects the localization of NR1I2 protein]
Rifampin results in increased expression of NR1I2 mRNA; Rifampin results in increased expression of NR1I2 protein
Rifampin results in increased localization of NR1I2 protein
[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; arsenite inhibits the reaction [Rifampin results in increased localization of NR1I2 protein]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]; sodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA]
Rifampin binds to NR1I2 gene mutant form
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]; Rifampin affects the localization of and results in increased activity of NR1I2 protein; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter; Rifampin binds to NR1I2 protein		 CTD PMID:11581012 PMID:12065438 PMID:12072427 PMID:12370413 PMID:12417264 More... NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions		 EXP
ISO		 Rifampin results in increased expression of NR1I3 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein
Rifampin results in increased expression of NR1I3 mRNA; Rifampin results in increased expression of NR1I3 protein
[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 protein		 CTD PMID:19118567 PMID:22733800 PMID:25835148 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression		 ISO Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; NR3C1 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
Rifampin results in increased expression of NR3C1 mRNA		 CTD PMID:10219967 PMID:12673034 PMID:12695351 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrl neural retina leucine zipper increases expression ISO Rifampin results in increased expression of NRL mRNA CTD PMID:24552687 NCBI chr15:29,008,104...29,009,832
Ensembl chr15:29,008,104...29,009,832 		JBrowse link
G Obsl1 obscurin like cytoskeletal adaptor 1 decreases expression ISO Rifampin results in decreased expression of OBSL1 mRNA CTD PMID:24552687 NCBI chr 9:76,967,802...76,993,565
Ensembl chr 9:76,974,253...76,993,560 		JBrowse link
G Ocln occludin affects localization ISO Rifampin affects the localization of OCLN protein CTD PMID:19577586 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Olr720 olfactory receptor 720 decreases expression ISO Rifampin results in decreased expression of OR4A47 mRNA CTD PMID:24552687 NCBI chr 3:75,873,971...75,874,900
Ensembl chr 3:75,871,362...75,879,648 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Rifampin results in decreased expression of P4HB mRNA CTD PMID:32535746 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein] CTD PMID:31678598 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pax7 paired box 7 decreases expression ISO Rifampin results in decreased expression of PAX7 mRNA CTD PMID:24552687 NCBI chr 5:151,996,368...152,098,023
Ensembl chr 5:151,999,092...152,097,979 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA] CTD PMID:24204015 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pclaf PCNA clamp associated factor increases expression ISO Rifampin results in increased expression of PCLAF mRNA CTD PMID:24552687 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994 		JBrowse link
G Pdap1 PDGFA associated protein 1 decreases expression ISO Rifampin results in decreased expression of PDAP1 mRNA CTD PMID:24552687 NCBI chr12:9,470,652...9,480,880
Ensembl chr12:9,470,574...9,535,374 		JBrowse link
G Pde4d phosphodiesterase 4D decreases expression ISO Rifampin results in decreased expression of PDE4D mRNA CTD PMID:24552687 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Peg3 paternally expressed 3 increases expression ISO Rifampin results in increased expression of PEG3 mRNA CTD PMID:24552687 NCBI chr 1:67,097,874...67,124,692
Ensembl chr 1:67,097,904...67,124,671 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha decreases expression ISO Rifampin results in decreased expression of PILRA mRNA CTD PMID:24552687
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA CTD PMID:21127053 NCBI chr17:81,496,669...81,668,180 JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel decreases expression ISO Rifampin results in decreased expression of PKD2L1 mRNA CTD PMID:24552687 NCBI chr 1:243,032,853...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Pklr pyruvate kinase L/R increases expression ISO Rifampin results in increased expression of PKLR mRNA CTD PMID:24552687 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Plat plasminogen activator, tissue type decreases expression ISO Rifampin results in decreased expression of PLAT mRNA CTD PMID:24552687 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Pon1 paraoxonase 1 increases expression ISO Rifampin results in increased expression of PON1 mRNA CTD PMID:26434531 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Por cytochrome p450 oxidoreductase increases activity ISO Rifampin results in increased activity of POR protein CTD PMID:12051692 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 decreases expression ISO Rifampin results in decreased expression of POU2F1 mRNA CTD PMID:16837569 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA CTD PMID:16292757 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression		 ISO Rifampin results in increased expression of and affects the localization of PPARG protein
Rifampin results in increased expression of PPARG mRNA		 CTD PMID:27806127 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [PPARGC1A protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:16857725 PMID:21292004 PMID:25069801 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A14 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA; PRKDC gene mutant form results in increased susceptibility to [Rifampin co-treated with Phenytoin co-treated with Monocrotaline] CTD PMID:21224054 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:31877331 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Prune1 prune exopolyphosphatase 1 decreases expression ISO Rifampin results in decreased expression of PRUNE1 mRNA CTD PMID:24552687 NCBI chr 2:182,830,575...182,859,972
Ensembl chr 2:182,830,578...182,859,336 		JBrowse link
G Psip1 PC4 and SFRS1 interacting protein 1 increases expression ISO Rifampin results in increased expression of PSIP1 mRNA CTD PMID:24552687 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257 		JBrowse link
G Psmc3ip PSMC3 interacting protein increases expression ISO Rifampin results in increased expression of PSMC3IP mRNA CTD PMID:24552687 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423 		JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA CTD PMID:21224054 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B decreases expression ISO Rifampin results in decreased expression of RIC8B mRNA CTD PMID:24552687 NCBI chr 7:18,746,716...18,843,264
Ensembl chr 7:18,748,641...18,842,372 		JBrowse link
G Rnf6 ring finger protein 6 decreases expression ISO Rifampin results in decreased expression of RNF6 mRNA CTD PMID:24552687 NCBI chr12:8,816,777...8,826,870
Ensembl chr12:8,816,833...8,826,847 		JBrowse link
G RragB Ras-related GTP binding B decreases expression ISO Rifampin results in decreased expression of RRAGB mRNA CTD PMID:24552687 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639 		JBrowse link
G Rspo3 R-spondin 3 decreases expression ISO Rifampin results in decreased expression of RSPO3 mRNA CTD PMID:24552687 NCBI chr 1:28,283,914...28,368,661
Ensembl chr 1:28,283,914...28,367,061 		JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Rifampin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression ISO Rifampin results in increased expression of HLA-DMA mRNA CTD PMID:24552687 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO
EXP		 1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]		 CTD PMID:12370413 PMID:16292757 PMID:16632523 PMID:21315811 PMID:25069801 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO Rifampin results in decreased expression of SCARB1 mRNA; Rifampin results in decreased expression of SCARB1 protein CTD PMID:15883047 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Rifampin results in increased expression of SCD1 mRNA CTD PMID:27806127 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Septin8 septin 8 increases expression ISO Rifampin results in increased expression of SEPTIN8 mRNA CTD PMID:24552687 NCBI chr10:37,684,639...37,713,704
Ensembl chr10:37,684,639...37,713,174 		JBrowse link
G Serpina4 serpin family A member 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA CTD PMID:21127053 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082 		JBrowse link
G Serpinb1a serpin family B member 1A multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA CTD PMID:21127053 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102 		JBrowse link
G Serpinb8 serpin family B member 8 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA CTD PMID:21127053 NCBI chr13:23,626,945...23,650,270
Ensembl chr13:23,626,945...23,650,835 		JBrowse link
G Serpinb9 serpin family B member 9 multiple interactions
increases expression		 ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA
Rifampin results in increased expression of SERPINB9 mRNA		 CTD PMID:21127053 PMID:24552687 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA		 CTD PMID:21127053 PMID:21224054 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfxn1 sideroflexin 1 decreases expression ISO Rifampin results in decreased expression of SFXN1 mRNA CTD PMID:24552687 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions
increases expression		 ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]
Rifampin results in increased expression of SGK2 mRNA		 CTD PMID:21127053 PMID:24204015 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480 		JBrowse link
G Sik2 salt-inducible kinase 2 decreases expression ISO Rifampin results in decreased expression of SIK2 mRNA CTD PMID:24552687 NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO Rifampin results in decreased expression of SLC10A1 mRNA CTD PMID:16837569 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc13a5 solute carrier family 13 member 5 increases expression ISO Rifampin results in increased expression of SLC13A5 mRNA; Rifampin results in increased expression of SLC13A5 protein CTD PMID:25628225 PMID:27199754 NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945 		JBrowse link
G Slc15a1 solute carrier family 15 member 1 decreases expression ISO Rifampin results in decreased expression of SLC15A1 mRNA CTD PMID:27199754 NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545 		JBrowse link
G Slc16a12 solute carrier family 16, member 12 increases expression
decreases expression		 ISO Rifampin results in increased expression of SLC16A12 mRNA
Rifampin results in decreased expression of SLC16A12 mRNA		 CTD PMID:24552687 PMID:27199754 NCBI chr 1:232,184,004...232,262,170
Ensembl chr 1:232,185,907...232,262,141 		JBrowse link
G Slc17a1 solute carrier family 17 member 1 decreases expression ISO Rifampin results in decreased expression of SLC17A1 mRNA CTD PMID:27199754 NCBI chr17:41,219,461...41,255,199 JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression ISO Rifampin results in decreased expression of SLC1A2 mRNA CTD PMID:27199754 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 decreases expression ISO Rifampin results in decreased expression of SLC20A2 mRNA CTD PMID:27199754 NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression
multiple interactions		 ISO Rifampin results in decreased expression of SLC22A1 mRNA; Rifampin results in decreased expression of SLC22A1 protein
[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]		 CTD PMID:26920453 PMID:27199754 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases expression ISO Rifampin results in decreased expression of SLC22A9 mRNA CTD PMID:27199754 NCBI chr 1:205,338,698...205,498,486
Ensembl chr 1:205,338,699...205,433,085 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO Rifampin results in decreased expression of SLC22A7 mRNA CTD PMID:16837569 PMID:27199754 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921 		JBrowse link
G Slc23a2 solute carrier family 23 member 2 increases expression ISO Rifampin results in increased expression of SLC23A2 mRNA CTD PMID:27199754 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343 		JBrowse link
G Slc23a3 solute carrier family 23, member 3 decreases expression ISO Rifampin results in decreased expression of SLC23A3 mRNA CTD PMID:27199754 NCBI chr 9:76,622,621...76,633,188
Ensembl chr 9:76,622,800...76,631,366 		JBrowse link
G Slc25a22 solute carrier family 25 member 22 increases expression ISO Rifampin results in increased expression of SLC25A22 mRNA CTD PMID:27199754 NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331 		JBrowse link
G Slc25a34 solute carrier family 25, member 34 decreases expression ISO Rifampin results in decreased expression of SLC25A34 mRNA CTD PMID:27199754 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Slc25a40 solute carrier family 25, member 40 decreases expression ISO Rifampin results in decreased expression of SLC25A40 mRNA CTD PMID:24552687 NCBI chr 4:25,620,007...25,676,422
Ensembl chr 4:25,589,360...25,676,472 		JBrowse link
G Slc26a2 solute carrier family 26 member 2 decreases expression ISO Rifampin results in decreased expression of SLC26A2 mRNA CTD PMID:27199754 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 decreases expression ISO Rifampin results in decreased expression of SLC26A4 mRNA CTD PMID:27199754 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO Rifampin results in increased expression of SLC27A1 mRNA CTD PMID:27806127 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression ISO Rifampin results in increased expression of SLC27A2 mRNA CTD PMID:27199754 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Slc27a3 solute carrier family 27 member 3 decreases expression ISO Rifampin results in decreased expression of SLC27A3 mRNA CTD PMID:27199754 NCBI chr 2:175,853,241...175,857,909
Ensembl chr 2:175,853,241...175,857,909 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression ISO Rifampin results in increased expression of SLC27A5 mRNA CTD PMID:27199754 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO Rifampin results in increased expression of SLC29A1 mRNA CTD PMID:27199754 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 increases expression ISO Rifampin results in increased expression of SLC29A4 mRNA CTD PMID:27199754 NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834 		JBrowse link
G Slc2a12 solute carrier family 2 member 12 increases expression ISO Rifampin results in increased expression of SLC2A12 mRNA CTD PMID:27199754 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions
decreases expression		 ISO NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]
Rifampin results in decreased expression of SLC2A2 mRNA; Rifampin results in decreased expression of SLC2A2 protein		 CTD PMID:26616219 PMID:27199754 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO Rifampin results in decreased expression of SLC30A10 mRNA CTD PMID:27199754 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO Rifampin results in decreased expression of SLC38A2 mRNA CTD PMID:27199754 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc3a1 solute carrier family 3 member 1 decreases expression ISO Rifampin results in decreased expression of SLC3A1 mRNA CTD PMID:27199754 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907 		JBrowse link
G Slc46a3 solute carrier family 46, member 3 increases expression ISO Rifampin results in increased expression of SLC46A3 mRNA CTD PMID:27199754 NCBI chr12:7,140,610...7,157,093
Ensembl chr12:7,140,668...7,157,092 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 increases expression ISO Rifampin results in increased expression of SLC47A1 mRNA CTD PMID:27199754 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc51a solute carrier family 51 subunit alpha increases expression ISO Rifampin results in increased expression of SLC51A mRNA CTD PMID:27199754 NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485 		JBrowse link
G Slc51b solute carrier family 51 subunit beta increases expression ISO Rifampin results in increased expression of SLC51B mRNA CTD PMID:27199754 NCBI chr 8:65,931,891...65,934,893
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slc5a11 solute carrier family 5 member 11 increases expression ISO Rifampin results in increased expression of SLC5A11 mRNA CTD PMID:27199754 NCBI chr 1:177,735,511...177,795,193
Ensembl chr 1:177,756,561...177,795,193 		JBrowse link
G Slc5a12 solute carrier family 5 member 12 increases expression ISO Rifampin results in increased expression of SLC5A12 mRNA CTD PMID:27199754 NCBI chr 3:97,179,326...97,228,405
Ensembl chr 3:97,179,326...97,228,405 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 increases expression ISO Rifampin results in increased expression of SLC6A12 mRNA CTD PMID:27199754 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a20 solute carrier family 6 member 20 increases expression ISO Rifampin results in increased expression of SLC6A20 mRNA CTD PMID:27199754 NCBI chr 8:123,282,325...123,322,609
Ensembl chr 8:123,281,472...123,322,573 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression ISO Rifampin results in increased expression of SLC6A9 mRNA CTD PMID:27199754 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Slc9a8 solute carrier family 9 member A8 increases expression ISO Rifampin results in increased expression of SLC9A8 mRNA CTD PMID:27199754 NCBI chr 3:156,147,855...156,198,497
Ensembl chr 3:156,148,104...156,198,471 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases activity
multiple interactions		 EXP Rifampin results in decreased activity of SLCO1B1 protein
[Rifampin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate		 CTD PMID:32259555 NCBI chr 4:174,877,045...174,950,857
Ensembl chr 4:174,876,593...174,950,873 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions
decreases activity		 EXP Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of Digoxin]
Rifampin results in decreased activity of SLCO1A4 protein		 CTD PMID:11883641 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions
decreases activity
decreases expression		 ISO Rifampin inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of fexofenadine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Hydroxyurea]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Ursodeoxycholic Acid metabolite]
Rifampin results in decreased activity of SLCO1B3 protein
Rifampin results in decreased expression of SLCO1B3 mRNA		 CTD PMID:17369605 PMID:18180276 PMID:21256917 PMID:21430235 PMID:27199754 More... NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 multiple interactions ISO Rifampin inhibits the reaction [decitabine results in increased expression of SLCO2A1 mRNA] CTD PMID:23137910 NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions
increases expression		 ISO Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]
Rifampin results in increased expression of SLCO2B1 mRNA		 CTD PMID:21430235 PMID:27199754 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases expression ISO Rifampin results in increased expression of SLCO4C1 mRNA CTD PMID:27199754 NCBI chr 9:97,180,162...97,229,135
Ensembl chr 9:97,178,861...97,229,715 		JBrowse link
G Smad9 SMAD family member 9 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA CTD PMID:21127053 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Snca synuclein alpha multiple interactions
increases sumoylation		 EXP Rifampin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein modified form]; UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:17280646 PMID:28132806 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA CTD PMID:21127053 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Rifampin results in decreased expression of SORBS1 mRNA CTD PMID:24552687 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sptb spectrin, beta, erythrocytic increases expression ISO Rifampin results in increased expression of SPTB mRNA CTD PMID:24552687 NCBI chr 6:95,310,342...95,437,221
Ensembl chr 6:95,310,326...95,437,118 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Rifampin results in increased expression of SQSTM1 protein CTD PMID:29908302 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO [SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA] CTD PMID:25069801 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA CTD PMID:21127053 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stk39 serine threonine kinase 39 increases expression ISO Rifampin results in increased expression of STK39 mRNA CTD PMID:24552687 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions ISO [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer] CTD PMID:21764778 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO
EXP		 [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter] CTD PMID:12370413 NCBI chr 1:75,451,178...75,508,142 JBrowse link
G Sumo1 small ubiquitin-like modifier 1 increases expression EXP Rifampin results in increased expression of SUMO1 protein CTD PMID:28132806 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Sumo3 small ubiquitin-like modifier 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr20:11,010,140...11,020,850
Ensembl chr20:11,010,166...11,020,696 		JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO Rifampin results in decreased expression of SUN1 mRNA CTD PMID:24552687 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571 		JBrowse link
G Tbata thymus, brain and testes associated decreases expression ISO Rifampin results in decreased expression of TBATA mRNA CTD PMID:24552687 NCBI chr20:29,118,055...29,135,124
Ensembl chr20:29,118,070...29,135,109 		JBrowse link
G Tfec transcription factor EC increases expression ISO Rifampin results in increased expression of TFEC mRNA CTD PMID:24552687 NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236 		JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 increases expression ISO Rifampin results in increased expression of THSD4 mRNA CTD PMID:24552687 NCBI chr 8:60,384,636...60,984,419 JBrowse link
G Tjp1 tight junction protein 1 affects localization
decreases expression		 ISO Rifampin affects the localization of TJP1 protein
Rifampin results in decreased expression of TJP1 mRNA		 CTD PMID:19577586 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tjp2 tight junction protein 2 decreases expression ISO Rifampin results in decreased expression of TJP2 mRNA CTD PMID:19577586 NCBI chr 1:221,709,745...221,838,383
Ensembl chr 1:221,709,745...221,838,295 		JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Rifampin results in increased expression of TLR1 mRNA CTD PMID:24552687 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
G Tmem120b transmembrane protein 120B decreases expression ISO Rifampin results in decreased expression of TMEM120B mRNA CTD PMID:24552687 NCBI chr12:33,447,441...33,487,257
Ensembl chr12:33,446,660...33,487,200 		JBrowse link
G Tmem145 transmembrane protein 145 increases expression ISO Rifampin results in increased expression of TMEM145 mRNA CTD PMID:24552687 NCBI chr 1:80,891,888...80,901,615
Ensembl chr 1:80,891,927...80,901,611 		JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Rifampin results in increased expression of TMEM88 mRNA CTD PMID:24552687 NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447 		JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression EXP
ISO		 Rifampin results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Rifampin results in decreased expression of TNF protein CTD PMID:21357946 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [Rifampin co-treated with Cobicistat] results in increased expression of TNFRSF10B mRNA CTD PMID:33629115 NCBI chr15:44,839,818...44,867,582 JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA CTD PMID:21224054 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA CTD PMID:21224054 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression ISO Rifampin results in increased expression of TSKU mRNA CTD PMID:24552687 PMID:27177772 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions EXP UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:28132806 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase multiple interactions
increases expression		 ISO [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA
Rifampin results in increased expression of UGDH mRNA		 CTD PMID:16292757 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression
increases expression
multiple interactions		 ISO Rifampin affects the expression of UGT1A1 mRNA
Rifampin results in increased expression of UGT1A1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of UGT1A1 mRNA		 CTD PMID:15104253 PMID:15771232 PMID:15849716 PMID:18098064 PMID:22126990 More... NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases expression
multiple interactions		 ISO Rifampin results in increased expression of UGT1A3 mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of UGT1A3 mRNA]		 CTD PMID:25313206 PMID:29356861 NCBI chr 9:88,791,216...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Rifampin results in increased expression of UGT1A6 mRNA CTD PMID:18094037 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases expression ISO Rifampin results in increased expression of UGT1A9 mRNA; Rifampin results in increased expression of UGT1A9 protein CTD PMID:25070100 NCBI chr 9:88,696,981...88,808,465 JBrowse link
G Uhrf2 ubiquitin like with PHD and ring finger domains 2 decreases expression ISO Rifampin results in decreased expression of UHRF2 mRNA CTD PMID:24552687 NCBI chr 1:227,814,639...227,877,907
Ensembl chr 1:227,814,963...227,877,904 		JBrowse link
G Ung uracil-DNA glycosylase multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA CTD PMID:21224054 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Rifampin results in increased expression of VEGFA protein CTD PMID:25051504 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfd vascular endothelial growth factor D multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA CTD PMID:21127053 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295 		JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 decreases expression ISO Rifampin results in decreased expression of VWA1 mRNA CTD PMID:24552687 NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO Rifampin results in increased expression of XIAP protein CTD PMID:12645856 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
G Zcchc13 zinc finger CCHC-type containing 13 decreases expression ISO Rifampin results in decreased expression of ZCCHC13 mRNA CTD PMID:24552687 NCBI chr  X:68,643,554...68,644,646
Ensembl chr  X:68,643,549...68,665,131 		JBrowse link
G Zfp11 zinc finger protein 11 decreases expression ISO Rifampin results in decreased expression of ZNF546 mRNA CTD PMID:24552687 NCBI chr12:27,028,067...27,040,846
Ensembl chr12:27,028,115...27,041,365 		JBrowse link
G Zfp451 zinc finger protein 451 decreases expression ISO Rifampin results in decreased expression of ZNF451 mRNA CTD PMID:24552687 NCBI chr 9:35,985,441...36,040,991
Ensembl chr 9:35,985,443...36,040,652 		JBrowse link
G Zfp46 zinc finger protein 46 decreases expression ISO Rifampin results in decreased expression of ZNF436 mRNA CTD PMID:24552687 NCBI chr 5:148,519,403...148,529,903
Ensembl chr 5:148,520,855...148,529,459 		JBrowse link
G Zfp462 zinc finger protein 462 decreases expression ISO Rifampin results in decreased expression of ZNF462 mRNA CTD PMID:24552687 NCBI chr 5:69,670,085...69,810,729
Ensembl chr 5:69,670,328...69,810,327 		JBrowse link
tinidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions		 ISO Tinidazole results in decreased activity of ABCB11 protein
Tinidazole inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]		 CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of Tinidazole CTD PMID:12920490 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19759
      application 19468
        pharmaceutical 19316
          drug 19316
            antiinfective agent 14118
              antiparasitic agent 9273
                antiamoebic agent 529
                  amphotericin B + 45
                  diloxanide furoate 0
                  emetine + 37
                  inuloxin A 0
                  iodoquinol 1
                  metronidazole + 93
                  metronidazole hydrochloride 0
                  ornidazole 1
                  rifampicin + 388
                  tinidazole 2
paths to the root