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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydrogensulfite
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Accession:CHEBI:17137 term browser browse the term
Definition:A sulfur oxoanion that has formula HO3S.
Synonyms:exact_synonym: hydrogen(trioxidosulfate)(1-);   hydrogensulfite(1-);   hydrogentrioxosulfate(1-);   hydrogentrioxosulfate(IV);   hydroxidodioxidosulfate(1-);   monohydrogentrioxosulfate
 related_synonym: Formula=HO3S;   HSO3-;   Hydrogen sulfite;   InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1;   InChIKey=LSNNMFCWUKXFEE-UHFFFAOYSA-M;   SMILES=OS([O-])=O;   [SO2(OH)](-);   bisulfite;   bisulphite;   hydrogen sulfite(1-);   hydrosulfite anion
 alt_id: CHEBI:13367;   CHEBI:5598
 xref: CAS:15181-46-1;   Gmelin:1455;   KEGG:C11481;   PDBeChem:SO3
 cyclic_relationship: is_conjugate_acid_of CHEBI:17359;   is_conjugate_base_of CHEBI:48854


show annotations for term's descendants           Sort by:
sodium hydrogensulfite term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP 6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; [sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; KT 5720 inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein] CTD PMID:21873648 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 decreases expression EXP sodium bisulfite results in decreased expression of COX4 mRNA CTD PMID:26980303 NCBI chr19:65,630,383...65,636,623
Ensembl chr19:48,721,199...48,727,921 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 decreases expression EXP sodium bisulfite results in decreased expression of ATP6 mRNA CTD PMID:26980303 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of ATP8 mRNA] CTD PMID:26980303 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of COX1 mRNA] CTD PMID:26980303 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression EXP sodium bisulfite results in decreased expression of COX2 mRNA CTD PMID:26980303 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions
decreases expression		 EXP TFAM protein inhibits the reaction [sodium bisulfite results in decreased expression of COX3 mRNA] CTD PMID:26980303 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO sodium bisulfite inhibits the reaction [Rotenone results in increased expression of NOS2 mRNA] CTD PMID:25086357 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA]
sodium bisulfite results in decreased expression of NRF1 mRNA; sodium bisulfite results in decreased expression of NRF1 protein		 CTD PMID:26980303 NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:58,664,957...58,825,328 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of PPARGC1A mRNA]
sodium bisulfite results in decreased expression of PPARGC1A mRNA; sodium bisulfite results in decreased expression of PPARGC1A protein		 CTD PMID:26980303 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptger2 prostaglandin E receptor 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER2 protein CTD PMID:21873648 NCBI chr15:20,694,765...20,708,475
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGER4 protein CTD PMID:21873648 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES mRNA CTD PMID:21873648 NCBI chr 3:34,575,643...34,586,987 JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions EXP [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGES2 mRNA CTD PMID:21873648 NCBI chr 3:36,088,246...36,095,430
Ensembl chr 3:15,690,501...15,697,688 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]] CTD PMID:21873648 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Cyclic AMP]; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]; [SC 560 results in decreased activity of PTGS1 protein] promotes the reaction [[N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased abundance of Dinoprostone]]; [sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; PTGS2 protein affects the susceptibility to [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Vitamin E inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]
sodium bisulfite inhibits the reaction [Rotenone results in increased expression of PTGS2 mRNA]; sodium bisulfite inhibits the reaction [Rotenone results in increased expression of PTGS2 protein]		 CTD PMID:21873648 PMID:25086357 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions
decreases expression		 EXP Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of TFAM mRNA]; TFAM protein inhibits the reaction [sodium bisulfite results in decreased expression of COX3 mRNA]
sodium bisulfite results in decreased expression of TFAM mRNA; sodium bisulfite results in decreased expression of TFAM protein		 CTD PMID:26980303 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO sodium bisulfite inhibits the reaction [Rotenone results in increased expression of TNF mRNA] CTD PMID:25086357 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      atom 19885
        nonmetal atom 19809
          sulfur atom 17774
            sulfur molecular entity 17774
              sulfur oxoanion 693
                hydrogensulfite 18
                  sodium hydrogensulfite 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      chalcogen 19580
                        oxygen atom 19551
                          oxygen molecular entity 19551
                            oxide 12885
                              oxoanion 10472
                                chalcogen oxoanion 695
                                  sulfur oxoanion 693
                                    hydrogensulfite 18
                                      sodium hydrogensulfite 18
paths to the root