Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Community Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hexanoate
go back to main search page
Accession:CHEBI:17120 term browser browse the term
Definition:A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid).
Synonyms:related_synonym: 1-hexanoate;   1-pentacarboxylate;   1-pentanecarboxylate;   CH3-[CH2]4-COO(-);   Formula=C6H11O2;   InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)/p-1;   InChIKey=FUZZWVXGSFPDMH-UHFFFAOYSA-M;   SMILES=CCCCCC([O-])=O;   butylacetate;   caproate;   capronate;   hexoate;   hexylate;   n-caproate;   n-hexanoate;   n-hexoate;   n-hexylate;   nPnCO2 anion;   pentanecarboxylate;   pentylformate
 alt_id: CHEBI:14398;   CHEBI:24569
 xref: Beilstein:3601453;   CAS:151-33-7;   ECMDB:ECMDB21229;   Gmelin:326340;   KEGG:C01585;   MetaCyc:HEXANOATE
 cyclic_relationship: is_conjugate_base_of CHEBI:30776


show annotations for term's descendants           Sort by:
6-aminohexanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Aminocaproic Acid results in decreased expression of A2M protein CTD PMID:11304663 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Folh1 folate hydrolase 1 multiple interactions ISO [2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein] CTD PMID:24508213 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
G Grpr gastrin releasing peptide receptor multiple interactions ISO [2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [bombesin, Tyr(4)- binds to GRPR protein] CTD PMID:24508213 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein] CTD PMID:17482686 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] CTD PMID:17482686 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Plg plasminogen multiple interactions ISO Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK1 protein]; Aminocaproic Acid inhibits the reaction [PLG protein results in increased phosphorylation of MAPK3 protein] CTD PMID:17482686 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Serpinc1 serpin family C member 1 increases expression ISO Aminocaproic Acid results in increased expression of SERPINC1 protein CTD PMID:11304663 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    role 19851
      biological role 19849
        biochemical role 19543
          metabolite 19529
            eukaryotic metabolite 19342
              plant metabolite 17926
                hexanoate 7
                  (3S,5S)-3,5-diaminohexanoate 0
                  1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine zwitterion 0
                  1-caproyl-sn-glycero-3-phosphate(2-) 0
                  1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion 0
                  2-amino-5-oxohexanoate 0
                  2-oxohexanoate 0
                  3-hydroxy-3-methylhexanoate 0
                  3-hydroxy-5-oxohexanoate 0
                  3-hydroxyhexanoate 0
                  3-oxohexanoate 0
                  4-hydroxy-2-oxohexanoate + 0
                  5-oxohexanoate 0
                  6-acetamido-3-aminohexanoate 0
                  6-acetamido-3-oxohexanoate 0
                  6-aminohexanoate 7
                  6-hydroxyhexanoate 0
                  6-oxohexanoate 0
                  L-2-aminohexanoate 0
                  N(6)-hexanoyl-L-lysine residue 0
                  N-(6-aminohexanoyl)-6-aminohexanoate 0
                  O-hexanoyl-L-serine residue 0
                  hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion 0
                  sodium hexanoate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic ion 9845
                              organic anion 3605
                                carboxylic acid anion 2474
                                  monocarboxylic acid anion 1587
                                    fatty acid anion 127
                                      saturated fatty acid anion 126
                                        straight-chain saturated fatty acid anion 8
                                          hexanoate 7
                                            (3S,5S)-3,5-diaminohexanoate 0
                                            1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine zwitterion 0
                                            1-caproyl-sn-glycero-3-phosphate(2-) 0
                                            1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion 0
                                            2-amino-5-oxohexanoate 0
                                            2-oxohexanoate 0
                                            3-hydroxy-3-methylhexanoate 0
                                            3-hydroxy-5-oxohexanoate 0
                                            3-hydroxyhexanoate 0
                                            3-oxohexanoate 0
                                            4-hydroxy-2-oxohexanoate + 0
                                            5-oxohexanoate 0
                                            6-acetamido-3-aminohexanoate 0
                                            6-acetamido-3-oxohexanoate 0
                                            6-aminohexanoate 7
                                            6-hydroxyhexanoate 0
                                            6-oxohexanoate 0
                                            L-2-aminohexanoate 0
                                            N(6)-hexanoyl-L-lysine residue 0
                                            N-(6-aminohexanoyl)-6-aminohexanoate 0
                                            O-hexanoyl-L-serine residue 0
                                            hexanoyl-sn-glycero-3-phosphoethanolamine zwitterion 0
                                            sodium hexanoate 0
paths to the root