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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phosphoramide
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Accession:CHEBI:17102 term browser browse the term
Definition:A compound in which one or more of the OH groups of phosphoric acid have been replaced with an amino or substituted amino group. The term is commonly confined to the phosphoric triamides, P(=O)(NR2)3, since replacement of one or two OH groups produces phosphoramidic acids: P(=O)(OH)(NR2)2 , P(=O)(OH)2(NR2).
Synonyms:related_synonym: phosphamide;   phosphamides;   phosphoramides
 alt_id: CHEBI:14827;   CHEBI:26076;   CHEBI:8162


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4-hydroperoxycyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO perfosfamide results in increased expression of ABL1 mRNA CTD PMID:19429390 NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G ACTB actin beta decreases expression ISO perfosfamide results in decreased expression of ACTB mRNA CTD PMID:19429390 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G AGT angiotensinogen decreases response to substance EXP AGT protein results in decreased susceptibility to perfosfamide CTD PMID:11034089 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,702,523...230,714,122
Ensembl chr 1:230,702,523...230,714,122
JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions
increases response to substance
EXP Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of AIFM1 protein]; perfosfamide results in increased expression of and results in increased localization of AIFM1 protein
AIFM1 results in increased susceptibility to perfosfamide
CTD PMID:18034189 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 affects response to substance EXP AKR1B10 protein affects the susceptibility to perfosfamide CTD PMID:18473730 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 decreases response to substance EXP ALDH1A1 protein results in decreased susceptibility to perfosfamide CTD PMID:8662658 PMID:16614850 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 decreases response to substance EXP ALDH1A2 protein results in decreased susceptibility to perfosfamide CTD PMID:22079344 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
JBrowse link
G ALDH1B1 aldehyde dehydrogenase 1 family member B1 affects response to substance EXP ALDH1B1 protein affects the susceptibility to perfosfamide CTD PMID:18473730 NCBI chr 9:38,392,702...38,398,665
Ensembl chr 9:38,392,702...38,398,661
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member decreases response to substance EXP ALDH2 protein results in decreased susceptibility to perfosfamide CTD PMID:22079344 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 decreases response to substance EXP ALDH3A1 protein results in decreased susceptibility to perfosfamide CTD PMID:16614850 NCBI chr17:19,737,984...19,748,390
Ensembl chr17:19,737,984...19,748,943
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression ISO perfosfamide results in decreased expression of APEX1 mRNA CTD PMID:11754170 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
affects folding
increases expression
EXP
ISO
Acetylcysteine inhibits the reaction [perfosfamide affects the folding of BAX protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of BAX]; perfosfamide results in increased expression of and results in increased localization of BAX
perfosfamide results in increased expression of BAX protein
CTD PMID:16488414 PMID:18034189 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 increases expression ISO perfosfamide results in increased expression of BBC3 mRNA CTD PMID:17068108 NCBI chr19:47,220,822...47,232,998
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B decreases expression ISO perfosfamide results in decreased expression of BMPR1B mRNA CTD PMID:19429390 NCBI chr 4:94,757,955...95,158,453
Ensembl chr 4:94,757,955...95,158,448
JBrowse link
G C1D C1D nuclear receptor corepressor increases expression ISO perfosfamide results in increased expression of C1D mRNA CTD PMID:19429390 NCBI chr 2:68,041,130...68,063,004
Ensembl chr 2:68,041,130...68,110,948
JBrowse link
G CASP3 caspase 3 increases activity
multiple interactions
EXP
ISO
perfosfamide results in increased activity of CASP3
perfosfamide promotes the reaction [TNF results in increased activity of CASP3 protein]
CTD PMID:16488414 PMID:17434952 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 increases activity ISO perfosfamide results in increased activity of CASP9 protein CTD PMID:16488414 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP
ISO
perfosfamide results in increased expression of CDKN1A
perfosfamide results in increased expression of CDKN1A mRNA; perfosfamide results in increased expression of CDKN1A protein
CTD PMID:17068108 PMID:18034189 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 decreases expression ISO perfosfamide results in decreased expression of CXCL9 mRNA CTD PMID:19429390 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G E2F1 E2F transcription factor 1 increases expression ISO perfosfamide results in increased expression of E2F1 mRNA CTD PMID:19429390 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G EGR1 early growth response 1 decreases expression ISO perfosfamide results in decreased expression of EGR1 mRNA CTD PMID:19429390 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ENDOG endonuclease G increases response to substance
multiple interactions
EXP ENDOG results in increased susceptibility to perfosfamide
Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of ENDOG protein]; perfosfamide results in increased expression of and results in increased localization of ENDOG protein
CTD PMID:18034189 NCBI chr 9:128,818,402...128,822,676
Ensembl chr 9:128,818,500...128,822,676
JBrowse link
G EPAS1 endothelial PAS domain protein 1 increases expression ISO perfosfamide results in increased expression of EPAS1 protein CTD PMID:23251655 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPHA6 EPH receptor A6 decreases expression ISO perfosfamide results in decreased expression of EPHA6 mRNA CTD PMID:19429390 NCBI chr 3:96,814,581...97,761,532
Ensembl chr 3:96,814,581...97,752,460
JBrowse link
G EYA1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO perfosfamide results in decreased expression of EYA1 mRNA CTD PMID:19429390 NCBI chr 8:71,197,433...71,548,104
Ensembl chr 8:71,197,433...71,592,025
JBrowse link
G FASLG Fas ligand increases expression EXP perfosfamide results in increased expression of FASLG mRNA; perfosfamide results in increased expression of FASLG protein CTD PMID:14760101 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FOXF1 forkhead box F1 affects expression ISO perfosfamide affects the expression of FOXF1 mRNA CTD PMID:19429390 NCBI chr16:86,510,527...86,515,422
Ensembl chr16:86,510,527...86,515,422
JBrowse link
G GJC1 gap junction protein gamma 1 increases expression ISO perfosfamide results in increased expression of GJC1 mRNA CTD PMID:19429390 NCBI chr17:44,794,988...44,831,364
Ensembl chr17:44,798,448...44,830,816
JBrowse link
G GLI2 GLI family zinc finger 2 decreases expression ISO perfosfamide results in decreased expression of GLI2 mRNA CTD PMID:19429390 NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653
JBrowse link
G HES1 hes family bHLH transcription factor 1 increases expression ISO perfosfamide results in increased expression of HES1 mRNA CTD PMID:19429390 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression ISO perfosfamide results in increased expression of HIF1A mRNA; perfosfamide results in increased expression of HIF1A protein CTD PMID:19429390 PMID:23251655 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HOXA11 homeobox A11 decreases expression ISO perfosfamide results in decreased expression of HOXA11 mRNA CTD PMID:19429390 NCBI chr 7:27,181,157...27,185,232
Ensembl chr 7:27,181,157...27,185,232
Ensembl chr 7:27,181,157...27,185,232
JBrowse link
G HOXA13 homeobox A13 increases expression ISO perfosfamide results in increased expression of HOXA13 mRNA CTD PMID:19429390 NCBI chr 7:27,194,364...27,200,091
Ensembl chr 7:27,193,503...27,200,091
JBrowse link
G HOXD10 homeobox D10 increases expression ISO perfosfamide results in increased expression of HOXD10 mRNA CTD PMID:19429390 NCBI chr 2:176,116,778...176,119,937
Ensembl chr 2:176,108,790...176,119,942
Ensembl chr 2:176,108,790...176,119,942
JBrowse link
G HRAS HRas proto-oncogene, GTPase decreases expression ISO perfosfamide results in decreased expression of HRAS mRNA CTD PMID:19429390 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,287
JBrowse link
G KL klotho decreases expression ISO perfosfamide results in decreased expression of KL mRNA CTD PMID:19429390 NCBI chr13:33,016,063...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G LIG3 DNA ligase 3 decreases expression ISO perfosfamide results in decreased expression of LIG3 mRNA CTD PMID:11754170 NCBI chr17:34,980,504...35,009,743
Ensembl chr17:34,980,512...35,009,743
JBrowse link
G MDM2 MDM2 proto-oncogene increases expression EXP perfosfamide results in increased expression of MDM2 CTD PMID:18034189 NCBI chr12:68,808,149...68,850,686
Ensembl chr12:68,808,177...68,850,686
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase decreases expression ISO perfosfamide results in decreased expression of MGMT mRNA CTD PMID:11754170 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MLH1 mutL homolog 1 decreases expression ISO perfosfamide results in decreased expression of MLH1 mRNA CTD PMID:11754170 NCBI chr 3:36,993,487...37,050,846
Ensembl chr 3:36,993,350...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MPG N-methylpurine DNA glycosylase decreases expression ISO perfosfamide results in decreased expression of MPG mRNA CTD PMID:11754170 NCBI chr16:77,007...85,846
Ensembl chr16:77,007...85,853
Ensembl chr16:77,007...85,853
JBrowse link
G MRE11 MRE11 homolog, double strand break repair nuclease decreases expression ISO perfosfamide results in decreased expression of MRE11A mRNA CTD PMID:11754170 NCBI chr11:94,415,570...94,512,701
Ensembl chr11:94,415,578...94,493,908
Ensembl chr11:94,415,578...94,493,908
JBrowse link
G MYO1B myosin IB increases expression ISO perfosfamide results in increased expression of MYO1B mRNA CTD PMID:19429390 NCBI chr 2:191,245,400...191,425,386
Ensembl chr 2:191,245,185...191,425,389
JBrowse link
G MYOG myogenin increases expression ISO perfosfamide results in increased expression of MYOG mRNA CTD PMID:19429390 NCBI chr 1:203,083,129...203,086,012
Ensembl chr 1:203,083,129...203,086,012
JBrowse link
G NDN necdin, MAGE family member increases expression ISO perfosfamide results in increased expression of NDN mRNA CTD PMID:19429390 NCBI chr15:23,685,400...23,687,305
Ensembl chr15:23,685,400...23,687,305
JBrowse link
G ODC1 ornithine decarboxylase 1 decreases expression ISO perfosfamide results in decreased expression of ODC1 mRNA CTD PMID:19429390 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G PEA15 proliferation and apoptosis adaptor protein 15 decreases expression ISO perfosfamide results in decreased expression of PEA15 mRNA CTD PMID:19429390 NCBI chr 1:160,205,384...160,215,376
Ensembl chr 1:160,205,337...160,215,376
Ensembl chr 1:160,205,337...160,215,376
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO perfosfamide results in increased expression of PMAIP1 mRNA CTD PMID:17068108 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,948...59,904,306
Ensembl chr18:59,899,948...59,904,306
JBrowse link
G PMS1 PMS1 homolog 1, mismatch repair system component decreases expression ISO perfosfamide results in decreased expression of PMS1 mRNA CTD PMID:11754170 NCBI chr 2:189,784,142...189,877,629
Ensembl chr 2:189,784,085...189,877,629
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component decreases expression ISO perfosfamide results in decreased expression of PMS2 mRNA CTD PMID:11754170 NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,106
JBrowse link
G POLB DNA polymerase beta decreases expression ISO perfosfamide results in decreased expression of POLB mRNA CTD PMID:11754170 NCBI chr 8:42,338,452...42,371,810
Ensembl chr 8:42,338,454...42,371,808
JBrowse link
G POLD1 DNA polymerase delta 1, catalytic subunit decreases expression ISO perfosfamide results in decreased expression of POLD1 mRNA CTD PMID:19429390 NCBI chr19:50,384,291...50,418,018
Ensembl chr19:50,384,204...50,418,018
JBrowse link
G RAD21 RAD21 cohesin complex component decreases expression ISO perfosfamide results in decreased expression of RAD21 mRNA CTD PMID:19429390 NCBI chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776
Ensembl chr 8:116,845,934...116,874,776
JBrowse link
G RAD50 RAD50 double strand break repair protein decreases expression ISO perfosfamide results in decreased expression of RAD50 mRNA CTD PMID:11754170 NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
JBrowse link
G RAD51 RAD51 recombinase decreases expression ISO perfosfamide results in decreased expression of RAD51 mRNA CTD PMID:11754170 NCBI chr15:40,694,774...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
G SDF4 stromal cell derived factor 4 decreases expression ISO perfosfamide results in decreased expression of SDF4 mRNA CTD PMID:19429390 NCBI chr 1:1,216,908...1,232,005
Ensembl chr 1:1,216,908...1,232,067
Ensembl chr 1:1,216,908...1,232,067
JBrowse link
G SFRP2 secreted frizzled related protein 2 decreases expression ISO perfosfamide results in decreased expression of SFRP2 mRNA CTD PMID:19429390 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
G SLC30A4 solute carrier family 30 member 4 decreases expression ISO perfosfamide results in decreased expression of SLC30A4 mRNA CTD PMID:19429390 NCBI chr15:45,479,606...45,523,755
Ensembl chr15:45,479,606...45,522,755
JBrowse link
G SMAD1 SMAD family member 1 decreases expression ISO perfosfamide results in decreased expression of SMAD1 mRNA CTD PMID:19429390 NCBI chr 4:145,481,306...145,559,176
Ensembl chr 4:145,481,194...145,559,176
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member affects response to substance EXP TAP1 protein affects the susceptibility to perfosfamide CTD PMID:18473730 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,978
Ensembl chr 6:32,845,209...32,853,978
JBrowse link
G TCF12 transcription factor 12 increases expression ISO perfosfamide results in increased expression of TCF12 mRNA CTD PMID:19429390 NCBI chr15:56,918,090...57,292,595
Ensembl chr15:56,918,623...57,299,281
JBrowse link
G TERC telomerase RNA component decreases expression ISO perfosfamide results in decreased expression of TERC mRNA CTD PMID:24571982 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047
JBrowse link
G TERT telomerase reverse transcriptase decreases expression ISO perfosfamide results in decreased expression of TERT mRNA CTD PMID:24571982 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO perfosfamide promotes the reaction [TNF results in increased activity of CASP3 protein] CTD PMID:16488414 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
EXP
ISO
Acetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53]
perfosfamide results in increased expression of and results in increased phosphorylation of and results in increased activity of TRP53 protein
CTD PMID:17068108 PMID:18034189 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRIM27 tripartite motif containing 27 decreases expression ISO perfosfamide results in decreased expression of TRIM27 mRNA CTD PMID:19429390 NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988
JBrowse link
G TTF1 transcription termination factor 1 decreases expression ISO perfosfamide results in decreased expression of TTF1 mRNA CTD PMID:19429390 NCBI chr 9:132,375,548...132,406,840
Ensembl chr 9:132,375,548...132,406,851
JBrowse link
G UBB ubiquitin B decreases expression ISO perfosfamide results in decreased expression of UBB mRNA CTD PMID:19429390 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G VEGFA vascular endothelial growth factor A increases expression ISO perfosfamide results in increased expression of VEGFA mRNA CTD PMID:19429390 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIM vimentin decreases expression ISO perfosfamide results in decreased expression of VIM mRNA CTD PMID:19429390 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G WNT11 Wnt family member 11 increases expression ISO perfosfamide results in increased expression of WNT11 mRNA CTD PMID:19429390 NCBI chr11:76,186,325...76,210,842
Ensembl chr11:76,186,325...76,210,736
JBrowse link
G XRCC1 X-ray repair cross complementing 1 decreases expression ISO perfosfamide results in decreased expression of XRCC1 mRNA CTD PMID:11754170 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,040...43,580,473
Ensembl chr19:43,543,040...43,580,473
JBrowse link
G XRCC5 X-ray repair cross complementing 5 decreases expression ISO perfosfamide results in decreased expression of XRCC5 mRNA CTD PMID:11754170 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta decreases expression ISO perfosfamide results in decreased expression of YWHAZ mRNA CTD PMID:19429390 NCBI chr 8:100,916,523...100,954,068
Ensembl chr 8:100,916,523...100,953,388
JBrowse link
4-hydroxycyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of ALOX5 mRNA CTD PMID:25833159 NCBI chr10:45,374,209...45,446,121
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G BDKRB2 bradykinin receptor B2 multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of BDKRB2 mRNA CTD PMID:25833159 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G CD40 CD40 molecule multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of CD40 mRNA CTD PMID:25833159 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases chemical synthesis EXP CYP2B6 protein results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:24819615 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 multiple interactions EXP [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:30500380 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 increases chemical synthesis EXP CYP2C9 protein results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:24819615 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions EXP [CYP3A4 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide CTD PMID:30500380 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G IL1R1 interleukin 1 receptor type 1 multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of IL1R1 mRNA CTD PMID:25833159 NCBI chr 2:102,069,638...102,179,874
Ensembl chr 2:102,064,544...102,179,874
JBrowse link
G IL2RG interleukin 2 receptor subunit gamma multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of IL2RG mRNA CTD PMID:25833159 NCBI chr  X:71,107,404...71,111,577
Ensembl chr  X:71,107,404...71,112,108
JBrowse link
G KLK15 kallikrein related peptidase 15 multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of KLK15 mRNA CTD PMID:25833159 NCBI chr19:50,825,289...50,834,337
Ensembl chr19:50,825,289...50,837,213
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions ISO [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of MAPK14 mRNA CTD PMID:25833159 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
acephate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions
decreases activity
ISO methamidophos inhibits the reaction [acephate results in decreased activity of ACHE protein] CTD PMID:9074804 PMID:11048668 PMID:12039681 PMID:22778074 PMID:23000449 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ALAD aminolevulinate dehydratase decreases activity EXP acephate results in decreased activity of ALAD protein CTD PMID:8687997 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALPL alkaline phosphatase, biomineralization associated multiple interactions EXP acephate inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 1:21,508,984...21,578,412
Ensembl chr 1:21,509,397...21,578,410
JBrowse link
G BCHE butyrylcholinesterase decreases expression ISO acephate results in decreased expression of BCHE protein CTD PMID:31326399 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G CAT catalase multiple interactions
decreases activity
ISO [acephate co-treated with methamidophos co-treated with Nicotine] results in increased activity of CAT protein; [Phorate co-treated with acephate co-treated with Dichlorvos co-treated with Dimethoate] results in decreased activity of CAT protein
acephate results in decreased activity of CAT protein
CTD PMID:10874619 PMID:22034174 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CRH corticotropin releasing hormone increases expression
increases secretion
multiple interactions
ISO acephate results in increased expression of CRH mRNA
acephate results in increased secretion of CRH protein
acephate promotes the reaction [FOS protein binds to CRH promoter]; Atropine inhibits the reaction [acephate results in increased expression of CRH mRNA]; Atropine inhibits the reaction [acephate results in increased secretion of CRH protein]; gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased expression of CRH mRNA]; gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased secretion of CRH protein]; Propranolol inhibits the reaction [acephate results in increased expression of CRH mRNA]; Propranolol inhibits the reaction [acephate results in increased secretion of CRH protein]
CTD PMID:12039681 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions ISO [acephate co-treated with vinclozolin] affects the expression of CYP1A1 protein; [fenarimol co-treated with acephate] affects the expression of CYP1A1 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A1 protein CTD PMID:17686559 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions ISO [fenarimol co-treated with acephate] affects the expression of CYP1A2 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A2 protein CTD PMID:17686559 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions ISO [acephate co-treated with vinclozolin] affects the expression of CYP2B1 protein; [fenarimol co-treated with acephate] affects the expression of CYP2B1 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2B1 protein CTD PMID:17686559 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO [acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein; [fenarimol co-treated with acephate] affects the expression of CYP2E1 protein; [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein CTD PMID:17686559 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO acephate promotes the reaction [FOS protein binds to CRH promoter] CTD PMID:12039681 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
increases activity
ISO diphenyldiselenide inhibits the reaction [acephate results in increased activity of G6PC1 protein] CTD PMID:22778074 NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
JBrowse link
G GPT glutamic--pyruvic transaminase decreases expression ISO acephate results in decreased expression of GPT protein CTD PMID:33217513 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 multiple interactions EXP acephate inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; acephate inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr 4:148,078,764...148,444,698
Ensembl chr 4:148,078,762...148,444,698
JBrowse link
G TAT tyrosine aminotransferase multiple interactions
increases activity
ISO diphenyldiselenide inhibits the reaction [acephate results in increased activity of TAT protein] CTD PMID:19118596 PMID:22778074 NCBI chr16:71,565,660...71,577,092
Ensembl chr16:71,565,660...71,577,092
JBrowse link
cyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions
decreases expression
increases expression
EXP
ISO
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]
Cyclophosphamide results in decreased expression of ABCB1 mRNA; Cyclophosphamide results in decreased expression of ABCB1A mRNA
CTD PMID:12576456 PMID:20041327 PMID:20623750 PMID:30563925 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 multiple interactions
decreases response to substance
EXP ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
ABCC1 protein results in decreased susceptibility to Cyclophosphamide
CTD PMID:11778547 PMID:12576456 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,577...16,143,074
Ensembl chr16:15,949,577...16,143,074
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions EXP ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ABHD3 abhydrolase domain containing 3, phospholipase increases expression EXP Cyclophosphamide results in increased expression of ABHD3 mRNA CTD PMID:21527772 NCBI chr18:21,650,901...21,704,793
Ensembl chr18:21,650,901...21,704,780
JBrowse link
G ABI2 abl interactor 2 decreases expression ISO Cyclophosphamide results in decreased expression of ABI2 mRNA CTD PMID:27466211 NCBI chr 2:203,325,013...203,432,169
Ensembl chr 2:203,328,280...203,447,728
Ensembl chr 2:203,328,280...203,447,728
JBrowse link
G ACE angiotensin I converting enzyme decreases expression ISO Cyclophosphamide results in decreased expression of ACE mRNA CTD PMID:27281708 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 decreases expression EXP Cyclophosphamide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,561,033...15,602,148
Ensembl chr  X:15,561,033...15,602,148
JBrowse link
G ACKR3 atypical chemokine receptor 3 increases expression ISO Cyclophosphamide results in increased expression of ACKR3 mRNA CTD PMID:20032115 NCBI chr 2:236,537,131...236,582,358
Ensembl chr 2:236,567,787...236,582,354
JBrowse link
G ACOD1 aconitate decarboxylase 1 increases expression ISO Cyclophosphamide results in increased expression of ACOD1 mRNA CTD PMID:15331540 NCBI chr13:76,948,511...76,958,638
Ensembl chr13:76,948,511...76,958,638
JBrowse link
G ACTB actin beta decreases expression
affects expression
EXP
ISO
Cyclophosphamide results in decreased expression of ACTB mRNA
Cyclophosphamide affects the expression of ACTB mRNA
CTD PMID:10859244 PMID:12167460 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADAM29 ADAM metallopeptidase domain 29 decreases expression ISO Cyclophosphamide results in decreased expression of ADAM24 mRNA CTD PMID:27281708 NCBI chr 4:174,918,358...174,978,180
Ensembl chr 4:174,829,668...174,978,180
JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 increases expression ISO Cyclophosphamide results in increased expression of ADAMTS9 mRNA CTD PMID:27281708 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000
JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 affects expression
increases expression
ISO Cyclophosphamide affects the expression of ADCYAP1 mRNA
Cyclophosphamide results in increased expression of ADCYAP1 protein
CTD PMID:9776515 PMID:10754506 PMID:18563302 NCBI chr18:904,384...912,172
Ensembl chr18:904,871...912,172
JBrowse link
G ADCYAP1R1 ADCYAP receptor type I affects expression ISO Cyclophosphamide affects the expression of ADCYAP1R1 mRNA CTD PMID:18563302 NCBI chr 7:31,052,308...31,111,474
Ensembl chr 7:31,052,308...31,111,479
Ensembl chr 7:31,052,308...31,111,479
JBrowse link
G ADM adrenomedullin affects response to substance EXP ADM protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G AFP alpha fetoprotein affects expression ISO Cyclophosphamide affects the expression of AFP protein CTD PMID:6177358 NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
JBrowse link
G AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase affects response to substance EXP AGL protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:99,850,077...99,924,023
Ensembl chr 1:99,850,361...99,924,023
JBrowse link
G AKAP8 A-kinase anchoring protein 8 increases expression ISO Cyclophosphamide results in increased expression of AKAP8 mRNA CTD PMID:27281708 NCBI chr19:15,353,385...15,379,787
Ensembl chr19:15,353,385...15,379,798
Ensembl chr19:15,353,385...15,379,798
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
ISO Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of AKT1 protein] CTD PMID:19996110 PMID:25446862 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions EXP [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 9:113,386,312...113,401,301
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALCAM activated leukocyte cell adhesion molecule increases expression ISO Cyclophosphamide results in increased expression of ALCAM mRNA CTD PMID:21041162 NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900
JBrowse link
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 affects response to substance
increases expression
decreases response to substance
EXP ALDH1A1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of ALDH1A1 mRNA
ALDH1A1 protein results in decreased susceptibility to Cyclophosphamide
CTD PMID:12513786 PMID:17403535 PMID:18854779 NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member increases expression EXP Cyclophosphamide results in increased expression of ALDH2 mRNA CTD PMID:17403535 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
JBrowse link
G ALDH3A1 aldehyde dehydrogenase 3 family member A1 affects response to substance EXP ALDH3A1 protein affects the susceptibility to Cyclophosphamide CTD PMID:18854779 NCBI chr17:19,737,984...19,748,390
Ensembl chr17:19,737,984...19,748,943
JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein decreases expression EXP Cyclophosphamide results in decreased expression of ALOX5AP mRNA CTD PMID:17403535 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426
JBrowse link
G ALYREF Aly/REF export factor decreases expression ISO Cyclophosphamide results in decreased expression of ALYREF mRNA CTD PMID:21041162 NCBI chr17:81,887,835...81,891,587
Ensembl chr17:81,887,835...81,891,586
JBrowse link
G AMFR autocrine motility factor receptor multiple interactions EXP AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr16:56,361,452...56,425,545
Ensembl chr16:56,361,452...56,425,545
JBrowse link
G ANGPT1 angiopoietin 1 increases expression EXP Cyclophosphamide results in increased expression of ANGPT1 mRNA CTD PMID:17403535 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055
JBrowse link
G APAF1 apoptotic peptidase activating factor 1 decreases expression EXP Cyclophosphamide results in decreased expression of APAF1 mRNA CTD PMID:29445054 NCBI chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
Ensembl chr12:98,645,141...98,735,433
JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression ISO Cyclophosphamide results in increased expression of APEX1 mRNA CTD PMID:11599041 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
JBrowse link
G APOB apolipoprotein B decreases expression ISO Cyclophosphamide results in decreased expression of APOB mRNA CTD PMID:18246545 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073
JBrowse link
G APOE apolipoprotein E decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of APOE mRNA
Cyclophosphamide results in increased expression of APOE mRNA
CTD PMID:15331540 PMID:21041162 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ARG1 arginase 1 increases expression
decreases expression
affects expression
ISO Cyclophosphamide results in increased expression of ARG1 mRNA
Cyclophosphamide results in decreased expression of ARG1 mRNA
Cyclophosphamide affects the expression of ARG1 mRNA
CTD PMID:18246545 PMID:21068404 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta increases expression EXP Cyclophosphamide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728
JBrowse link
G ARHGEF26 Rho guanine nucleotide exchange factor 26 increases expression EXP Cyclophosphamide results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 3:154,121,003...154,257,827
Ensembl chr 3:154,121,003...154,257,827
JBrowse link
G ASNS asparagine synthetase (glutamine-hydrolyzing) decreases expression EXP Cyclophosphamide metabolite results in decreased expression of ASNS mRNA CTD PMID:24356939 NCBI chr 7:97,851,677...97,928,441
Ensembl chr 7:97,851,677...97,872,542
JBrowse link
G ATF2 activating transcription factor 2 increases expression ISO Cyclophosphamide results in increased expression of ATF2 mRNA CTD PMID:11599041 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
JBrowse link
G ATF5 activating transcription factor 5 decreases expression EXP Cyclophosphamide results in decreased expression of ATF5 mRNA CTD PMID:17403535 NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935
JBrowse link
G ATG3 autophagy related 3 decreases expression EXP Cyclophosphamide results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046
JBrowse link
G ATG5 autophagy related 5 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of ATG5 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein]
CTD PMID:32151603 NCBI chr 6:106,184,476...106,325,789
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G ATG7 autophagy related 7 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein] CTD PMID:32151603 NCBI chr 3:11,272,348...11,564,652
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G AURKB aurora kinase B increases expression ISO Cyclophosphamide results in increased expression of AURKB mRNA CTD PMID:11599041 NCBI chr17:8,204,731...8,210,767
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G AXL AXL receptor tyrosine kinase increases expression EXP Cyclophosphamide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766
JBrowse link
G B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 increases expression EXP Cyclophosphamide results in increased expression of B3GALNT2 mRNA CTD PMID:21527772 NCBI chr 1:235,440,654...235,504,481
Ensembl chr 1:235,447,190...235,504,452
JBrowse link
G BAD BCL2 associated agonist of cell death increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of BAD mRNA
Cyclophosphamide results in increased expression of BAD protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAD protein]
CTD PMID:11599041 PMID:29753871 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAG1 BAG cochaperone 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BAG1 mRNA CTD PMID:16322899 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of BAX mRNA; Cyclophosphamide results in increased expression of BAX protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]
CTD PMID:25446862 PMID:29753871 PMID:30506662 PMID:32197949 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of BBC3 mRNA
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA]
CTD PMID:32197949 NCBI chr19:47,220,822...47,232,998
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BBS4 Bardet-Biedl syndrome 4 multiple interactions EXP BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr15:72,686,204...72,738,476
Ensembl chr15:72,686,179...72,738,475
JBrowse link
G BCHE butyrylcholinesterase multiple interactions
decreases activity
EXP [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein
Cyclophosphamide results in decreased activity of BCHE protein
CTD PMID:4672170 PMID:4959505 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
increases expression
EXP
ISO
[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of BCL2 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of BCL2 protein; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BCL2 mRNA; [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Cyclophosphamide results in decreased expression of BCL2 mRNA; Cyclophosphamide results in decreased expression of BCL2 protein
Cyclophosphamide results in increased expression of BCL2 mRNA
CTD PMID:11723234 PMID:14503796 PMID:15582267 PMID:16322899 PMID:21182165 PMID:25446862 PMID:29753871 PMID:30506662 PMID:32197949 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 increases expression ISO Cyclophosphamide results in increased expression of BCL2L1 mRNA CTD PMID:11599041 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL2L11 BCL2 like 11 multiple interactions
increases expression
ISO sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA] CTD PMID:32197949 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,445
JBrowse link
G BCL2L2 BCL2 like 2 increases expression ISO Cyclophosphamide results in increased expression of BCL2L2 mRNA CTD PMID:21041162 NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,759
Ensembl chr14:23,298,790...23,311,759
JBrowse link
G BCL6 BCL6 transcription repressor decreases expression ISO
EXP
Cyclophosphamide results in decreased expression of BCL6 mRNA
Cyclophosphamide metabolite results in decreased expression of BCL6 mRNA
CTD PMID:21041162 PMID:24356939 NCBI chr 3:187,721,377...187,745,472
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G BDH1 3-hydroxybutyrate dehydrogenase 1 affects response to substance EXP BDH1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323
JBrowse link
G BDKRB1 bradykinin receptor B1 increases expression ISO Cyclophosphamide results in increased expression of BDKRB1 mRNA CTD PMID:10498854 PMID:15576455 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967
JBrowse link
G BDKRB2 bradykinin receptor B2 affects expression ISO Cyclophosphamide affects the expression of BDKRB2 mRNA CTD PMID:15576455 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BDNF brain derived neurotrophic factor increases expression ISO Cyclophosphamide results in increased expression of BDNF mRNA CTD PMID:10683293 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 multiple interactions
decreases expression
EXP
ISO
BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]
CTD PMID:16896004 PMID:32151603 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BIK BCL2 interacting killer decreases expression EXP Cyclophosphamide results in decreased expression of BIK mRNA CTD PMID:17403535 NCBI chr22:43,110,750...43,129,712
Ensembl chr22:43,110,750...43,129,712
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of BIRC3 mRNA CTD PMID:24356939 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G BLVRB biliverdin reductase B decreases expression ISO Cyclophosphamide results in decreased expression of BLVRB protein CTD PMID:9006340 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
JBrowse link
G BPI bactericidal permeability increasing protein decreases expression EXP Cyclophosphamide results in decreased expression of BPI mRNA CTD PMID:17403535 NCBI chr20:38,304,156...38,337,505
Ensembl chr20:38,304,150...38,337,505
Ensembl chr20:38,304,150...38,337,505
JBrowse link
G BRPF1 bromodomain and PHD finger containing 1 increases expression ISO Cyclophosphamide results in increased expression of BRPF1 mRNA CTD PMID:27281708 NCBI chr 3:9,731,729...9,748,015
Ensembl chr 3:9,731,729...9,748,015
JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Cyclophosphamide results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,690,275...62,709,845
JBrowse link
G BSG basigin (Ok blood group) decreases expression ISO Cyclophosphamide results in decreased expression of BSG mRNA CTD PMID:15331540 NCBI chr19:571,283...583,493
Ensembl chr19:571,277...583,493
Ensembl chr19:571,277...583,493
JBrowse link
G BTG1 BTG anti-proliferation factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of BTG1 mRNA CTD PMID:21041162 NCBI chr12:92,140,278...92,145,846
Ensembl chr12:92,140,278...92,145,846
JBrowse link
G BTG2 BTG anti-proliferation factor 2 increases expression EXP Cyclophosphamide results in increased expression of BTG2 mRNA CTD PMID:29445054 NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
JBrowse link
G BTG3 BTG anti-proliferation factor 3 multiple interactions EXP BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr21:17,593,653...17,612,940
Ensembl chr21:17,593,653...17,612,947
Ensembl chr21:17,593,653...17,612,947
JBrowse link
G BUB3 BUB3 mitotic checkpoint protein multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BUB3 mRNA CTD PMID:16322899 NCBI chr10:123,154,402...123,170,467
Ensembl chr10:123,154,402...123,170,467
JBrowse link
G C1QA complement C1q A chain increases expression ISO Cyclophosphamide results in increased expression of C1QA mRNA CTD PMID:21041162 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,636,628...22,639,678
JBrowse link
G C3 complement C3 increases expression ISO Cyclophosphamide results in increased expression of C3 mRNA CTD PMID:21041162 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CA12 carbonic anhydrase 12 multiple interactions EXP CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846
JBrowse link
G CA2 carbonic anhydrase 2 decreases expression
increases expression
EXP
ISO
Cyclophosphamide results in decreased expression of CA2 mRNA
Cyclophosphamide results in increased expression of CAR2 mRNA
CTD PMID:15331540 PMID:17403535 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CA7 carbonic anhydrase 7 decreases expression ISO Cyclophosphamide results in decreased expression of CAR7 mRNA CTD PMID:27281708 NCBI chr16:66,844,414...66,854,149
Ensembl chr16:66,844,414...66,854,153
JBrowse link
G CABP1 calcium binding protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of CABP1 mRNA CTD PMID:11906922 NCBI chr12:120,640,552...120,680,869
Ensembl chr12:120,640,552...120,667,324
JBrowse link
G CABP2 calcium binding protein 2 decreases expression ISO Cyclophosphamide results in decreased expression of CABP2 mRNA CTD PMID:11906922 NCBI chr11:67,518,912...67,523,446
Ensembl chr11:67,518,912...67,524,517
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H multiple interactions
increases expression
ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein
Cyclophosphamide results in increased expression of CACNA1H protein
CTD PMID:29129814 NCBI chr16:1,153,106...1,221,769
Ensembl chr16:1,153,106...1,221,771
JBrowse link
G CALR calreticulin increases expression
decreases expression
ISO Cyclophosphamide results in increased expression of CALR mRNA
Cyclophosphamide results in decreased expression of CALR mRNA
CTD PMID:11599041 PMID:11906922 PMID:18246545 NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489
JBrowse link
G CANX calnexin decreases expression ISO Cyclophosphamide results in decreased expression of CANX mRNA CTD PMID:11906922 NCBI chr 5:179,678,646...179,731,641
Ensembl chr 5:179,678,628...179,731,641
JBrowse link
G CAPN2 calpain 2 increases expression ISO Cyclophosphamide results in increased expression of CAPN2 mRNA CTD PMID:21041162 NCBI chr 1:223,701,597...223,776,018
Ensembl chr 1:223,701,593...223,776,018
JBrowse link
G CARS1 cysteinyl-tRNA synthetase 1 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of CARS1 mRNA CTD PMID:24356939 NCBI chr11:3,000,929...3,057,423
Ensembl chr11:3,000,922...3,057,613
JBrowse link
G CASP1 caspase 1 decreases expression
increases expression
EXP
ISO
Cyclophosphamide results in decreased expression of CASP1 mRNA
Cyclophosphamide results in increased expression of CASP1 mRNA
CTD PMID:17403535 PMID:21041162 NCBI chr11:105,025,443...105,035,591
Ensembl chr11:105,025,443...105,035,250
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
increases expression
decreases response to substance
EXP
ISO
[Bortezomib co-treated with oblimersen co-treated with Cyclophosphamide] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP3 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]
Cyclophosphamide results in increased expression of CASP3 protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]
Cyclophosphamide results in increased expression of CASP3 mRNA
CASP3 protein alternative form results in decreased susceptibility to Cyclophosphamide
CTD PMID:11723234 PMID:14503796 PMID:16675587 PMID:17020986 PMID:17898787 PMID:30506662 PMID:32197949 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP4 caspase 4 multiple interactions
increases cleavage
ISO sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein] CTD PMID:32197949 NCBI chr11:104,942,866...104,968,596
Ensembl chr11:104,942,866...104,969,366
JBrowse link
G CASP8 caspase 8 multiple interactions
increases response to substance
EXP [Methotrexate results in increased expression of CASP8 protein] which results in increased susceptibility to Cyclophosphamide metabolite; Cyclophosphamide metabolite results in increased expression of and results in increased cleavage of CASP8 protein; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP8 protein
CASP8 protein results in increased susceptibility to Cyclophosphamide metabolite
CTD PMID:17898787 PMID:22010212 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 multiple interactions
increases expression
increases activity
EXP
ISO
BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP9 protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP9 protein]
CTD PMID:11723234 PMID:17898787 PMID:30506662 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase decreases expression
decreases activity
affects activity
multiple interactions
ISO Cyclophosphamide results in decreased expression of CAT protein
Cyclophosphamide results in decreased activity of CAT protein
Cyclophosphamide results in decreased expression of CAT mRNA; Cyclophosphamide results in decreased expression of CAT protein
Cyclophosphamide affects the activity of CAT protein
Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]; cinnamic acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Eicosapentaenoic Acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CAT mRNA]
mangiferin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; pimagedine inhibits the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]
CTD PMID:16076520 PMID:19107871 PMID:20052769 PMID:20957680 PMID:21772021 PMID:22285266 PMID:23542512 PMID:23695977 PMID:25753322 PMID:27633142 PMID:29753871 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCIN calicin increases expression EXP Cyclophosphamide results in increased expression of CCIN protein CTD PMID:17475930 NCBI chr 9:36,169,388...36,171,334
Ensembl chr 9:36,169,388...36,171,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of CCL2 protein
Cyclophosphamide results in increased expression of CCL2 mRNA
CTD PMID:18848347 PMID:21068404 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL25 C-C motif chemokine ligand 25 decreases expression ISO Cyclophosphamide results in decreased expression of CCL25 mRNA CTD PMID:21041162 NCBI chr19:8,052,318...8,062,663
Ensembl chr19:8,052,767...8,062,650
Ensembl chr19:8,052,767...8,062,650
JBrowse link
G CCL3 C-C motif chemokine ligand 3 decreases expression ISO Cyclophosphamide results in decreased expression of CCL3 protein CTD PMID:21880982 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL7 C-C motif chemokine ligand 7 increases expression ISO Cyclophosphamide results in increased expression of CCL7 mRNA CTD PMID:15331540 PMID:21041162 NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
JBrowse link
G CCNA2 cyclin A2 decreases expression ISO Cyclophosphamide results in decreased expression of CCNA2 mRNA CTD PMID:21041162 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCND2 cyclin D2 increases expression ISO Cyclophosphamide results in increased expression of CCND2 mRNA CTD PMID:21041162 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353
Ensembl chr12:4,269,771...4,305,353
JBrowse link
G CCND3 cyclin D3 decreases expression ISO Cyclophosphamide results in decreased expression of CCND3 mRNA CTD PMID:21041162 NCBI chr 6:41,934,933...42,048,894
Ensembl chr 6:41,934,933...42,050,357
Ensembl chr 6:41,934,933...42,050,357
JBrowse link
G CCR5 C-C motif chemokine receptor 5 increases expression ISO Cyclophosphamide results in increased expression of CCR5 mRNA CTD PMID:15331540 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CCR8 C-C motif chemokine receptor 8 decreases expression EXP Cyclophosphamide results in decreased expression of CCR8 mRNA CTD PMID:17403535 NCBI chr 3:39,329,709...39,333,680
Ensembl chr 3:39,329,709...39,333,680
JBrowse link
G CCR9 C-C motif chemokine receptor 9 decreases expression ISO Cyclophosphamide results in decreased expression of CCR9 mRNA CTD PMID:21041162 NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,886,504...45,903,175
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 decreases expression ISO Cyclophosphamide results in decreased expression of CCT3 mRNA CTD PMID:11906922 NCBI chr 1:156,308,968...156,338,292
Ensembl chr 1:156,308,968...156,367,873
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 decreases expression ISO Cyclophosphamide results in decreased expression of CCT5 mRNA CTD PMID:11906922 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 decreases expression ISO Cyclophosphamide results in decreased expression of CCT7 mRNA CTD PMID:11906922 NCBI chr 2:73,233,425...73,253,008
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CD14 CD14 molecule increases expression ISO Cyclophosphamide results in increased expression of CD14 mRNA CTD PMID:15331540 PMID:21041162 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,701
JBrowse link
G CD151 CD151 molecule (Raph blood group) increases expression ISO Cyclophosphamide results in increased expression of CD151 mRNA CTD PMID:21041162 NCBI chr11:832,952...838,835
Ensembl chr11:832,887...839,831
JBrowse link
G CD2 CD2 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD2 mRNA CTD PMID:21041162 NCBI chr 1:116,754,430...116,769,229
Ensembl chr 1:116,754,430...116,769,229
JBrowse link
G CD27 CD27 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD27 mRNA CTD PMID:21041162 NCBI chr12:6,444,867...6,451,718
Ensembl chr12:6,444,867...6,451,718
Ensembl chr12:6,444,867...6,451,718
JBrowse link
G CD28 CD28 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD28 mRNA CTD PMID:21041162 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD38 CD38 molecule increases expression ISO Cyclophosphamide results in increased expression of CD38 mRNA CTD PMID:21041162 NCBI chr 4:15,778,328...15,853,232
Ensembl chr 4:15,778,275...15,853,232
JBrowse link
G CD3D CD3d molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD3D mRNA CTD PMID:21041162 NCBI chr11:118,338,954...118,342,705
Ensembl chr11:118,339,075...118,342,705
Ensembl chr11:118,339,075...118,342,705
JBrowse link
G CD3E CD3e molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD3E mRNA CTD PMID:21041162 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175
Ensembl chr11:118,304,730...118,316,175
JBrowse link
G CD3G CD3g molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD3G mRNA CTD PMID:21041162 NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161
JBrowse link
G CD4 CD4 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD4 mRNA CTD PMID:21041162 NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799
JBrowse link
G CD40 CD40 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD40 mRNA CTD PMID:21041162 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CD5 CD5 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD5 mRNA CTD PMID:21041162 NCBI chr11:61,093,963...61,127,852
Ensembl chr11:61,102,489...61,127,852
JBrowse link
G CD6 CD6 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD6 mRNA CTD PMID:21041162 NCBI chr11:60,971,678...61,020,377
Ensembl chr11:60,971,680...61,020,377
JBrowse link
G CD69 CD69 molecule decreases expression ISO
EXP
Cyclophosphamide results in decreased expression of CD69 mRNA
Cyclophosphamide metabolite results in decreased expression of CD69 mRNA
CTD PMID:21041162 PMID:24356939 NCBI chr12:9,752,486...9,760,901
Ensembl chr12:9,752,486...9,760,901
JBrowse link
G CD74 CD74 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD74 mRNA CTD PMID:15331540 NCBI chr 5:150,400,041...150,412,936
Ensembl chr 5:150,400,041...150,412,929
Ensembl chr 5:150,400,041...150,412,929
JBrowse link
G CD79B CD79b molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD79B mRNA CTD PMID:15331540 NCBI chr17:63,928,740...63,932,331
Ensembl chr17:63,928,740...63,932,354
Ensembl chr17:63,928,740...63,932,354
JBrowse link
G CD83 CD83 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD83 mRNA CTD PMID:15331540 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918
JBrowse link
G CD84 CD84 molecule increases expression EXP Cyclophosphamide metabolite results in increased expression of CD84 mRNA CTD PMID:24356939 NCBI chr 1:160,541,098...160,579,515
Ensembl chr 1:160,541,095...160,579,516
JBrowse link
G CD8A CD8a molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD8A mRNA CTD PMID:21041162 NCBI chr 2:86,784,605...86,808,396
Ensembl chr 2:86,784,610...86,808,396
JBrowse link
G CD8B CD8b molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD8B1 mRNA CTD PMID:21041162 NCBI chr 2:86,815,369...86,861,886
Ensembl chr 2:86,815,339...86,861,924
JBrowse link
G CDC20 cell division cycle 20 increases expression ISO Cyclophosphamide results in increased expression of CDC20 mRNA CTD PMID:11599041 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
JBrowse link
G CDH1 cadherin 1 affects expression ISO Cyclophosphamide affects the expression of CDH1 mRNA CTD PMID:10859244 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,541
Ensembl chr16:68,737,292...68,835,541
JBrowse link
G CDH2 cadherin 2 affects expression ISO Cyclophosphamide affects the expression of CDH2 mRNA CTD PMID:10859244 NCBI chr18:27,932,878...28,177,130
Ensembl chr18:27,932,879...28,177,946
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDH3 cadherin 3 affects expression ISO Cyclophosphamide affects the expression of CDH3 mRNA CTD PMID:10859244 NCBI chr16:68,644,914...68,727,573
Ensembl chr16:68,636,189...68,722,616
Ensembl chr16:68,636,189...68,722,616
JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression ISO Cyclophosphamide results in decreased expression of CDK2 mRNA CTD PMID:21041162 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP
ISO
Cyclophosphamide results in increased expression of CDKN1A mRNA CTD PMID:15331540 PMID:21527772 PMID:29445054 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CDKN1B mRNA CTD PMID:16322899 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,715,058...12,722,369
JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C increases expression ISO Cyclophosphamide results in increased expression of CDKN1C mRNA CTD PMID:21041162 NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775
Ensembl chr11:2,883,213...2,885,775
JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D decreases expression ISO Cyclophosphamide results in decreased expression of CDKN2D mRNA CTD PMID:21041162 NCBI chr19:10,566,460...10,568,979
Ensembl chr19:10,566,460...10,569,059
JBrowse link
G CEBPB CCAAT enhancer binding protein beta decreases expression EXP Cyclophosphamide metabolite results in decreased expression of CEBPB mRNA CTD PMID:24356939 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CEL carboxyl ester lipase increases expression EXP Cyclophosphamide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,978...133,071,863
Ensembl chr 9:133,061,978...133,071,863
Ensembl chr 9:133,061,978...133,071,863
JBrowse link
G CFB complement factor B increases expression ISO Cyclophosphamide results in increased expression of CFB mRNA CTD PMID:21041162 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G CFI complement factor I affects response to substance EXP CFI protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:109,730,982...109,802,040
Ensembl chr 4:109,740,694...109,802,179
Ensembl chr 4:109,740,694...109,802,179
JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of CHAC1 mRNA; Cyclophosphamide results in decreased expression of CHAC1 mRNA CTD PMID:23824090 PMID:24356939 NCBI chr15:40,942,137...40,956,518
Ensembl chr15:40,952,962...40,956,512
JBrowse link
G CHAMP1 chromosome alignment maintaining phosphoprotein 1 increases expression ISO Cyclophosphamide results in increased expression of CHAMP1 mRNA CTD PMID:27281708 NCBI chr13:114,314,503...114,327,322
Ensembl chr13:114,314,482...114,337,626
JBrowse link
G CHD5 chromodomain helicase DNA binding protein 5 decreases expression ISO Cyclophosphamide results in decreased expression of CHD5 mRNA CTD PMID:27281708 NCBI chr 1:6,101,787...6,180,321
Ensembl chr 1:6,101,787...6,180,321
JBrowse link
G CHGA chromogranin A decreases expression ISO Cyclophosphamide results in decreased expression of CHGA mRNA CTD PMID:15331540 NCBI chr14:92,922,594...92,935,293
Ensembl chr14:92,923,150...92,935,285
JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 increases expression ISO Cyclophosphamide results in increased expression of CHRM5 protein CTD PMID:16125470 NCBI chr15:33,968,497...34,067,458
Ensembl chr15:33,968,497...34,067,458
Ensembl chr15:33,968,497...34,067,458
JBrowse link
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 affects expression
decreases expression
ISO Cyclophosphamide affects the expression of CITED2 mRNA
Cyclophosphamide results in decreased expression of CITED2 mRNA
CTD PMID:18246545 NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
JBrowse link
G CLDN1 claudin 1 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein] CTD PMID:32151603 NCBI chr 3:190,305,707...190,322,446
Ensembl chr 3:190,305,707...190,322,446
JBrowse link
G CLDN4 claudin 4 multiple interactions
decreases expression
ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,693
Ensembl chr 7:73,799,542...73,832,693
JBrowse link
G CLIC4 chloride intracellular channel 4 increases expression ISO Cyclophosphamide results in increased expression of CLIC4 mRNA CTD PMID:15331540 NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
JBrowse link
G CLIP1 CAP-Gly domain containing linker protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of CLIP1 mRNA CTD PMID:27281708 NCBI chr12:122,271,432...122,422,956
Ensembl chr12:122,271,432...122,422,632
Ensembl chr12:122,271,432...122,422,632
JBrowse link
G COCH cochlin affects response to substance EXP COCH protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr14:30,874,496...30,890,618
Ensembl chr14:30,874,514...30,895,065
JBrowse link
G COMT catechol-O-methyltransferase increases expression ISO Cyclophosphamide results in increased expression of COMT mRNA CTD PMID:21041162 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,733...19,969,975
Ensembl chr22:19,941,733...19,969,975
Ensembl chr22:19,941,733...19,969,975
JBrowse link
G COX7A2 cytochrome c oxidase subunit 7A2 decreases expression EXP Cyclophosphamide results in decreased expression of COX7A2 mRNA CTD PMID:17403535 NCBI chr 6:75,237,675...75,250,298
Ensembl chr 6:75,237,675...75,250,323
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 increases expression EXP Cyclophosphamide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CREB1 cAMP responsive element binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of CREB1 protein modified form CTD PMID:18299998 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CREM cAMP responsive element modulator decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of CREM mRNA; Cyclophosphamide results in decreased expression of CREM protein
Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM mRNA]; Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM protein]
CTD PMID:17624719 NCBI chr10:35,126,830...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CRH corticotropin releasing hormone increases expression ISO Cyclophosphamide results in increased expression of CRH mRNA; Cyclophosphamide results in increased expression of CRH protein CTD PMID:15276878 PMID:16614059 PMID:17335920 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 increases expression ISO Cyclophosphamide results in increased expression of CRHR2 protein CTD PMID:16614059 NCBI chr 7:30,649,406...30,700,103
Ensembl chr 7:30,651,942...30,700,129
JBrowse link
G CSF1 colony stimulating factor 1 multiple interactions ISO [Cyclophosphamide co-treated with Sizofiran] results in increased expression of CSF1 mRNA CTD PMID:10052129 NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
JBrowse link
G CSF2 colony stimulating factor 2 affects activity
increases expression
EXP
ISO
CSF2 protein affects the activity of Cyclophosphamide
Cyclophosphamide results in increased expression of CSF2 protein
CTD PMID:8349185 PMID:18848347 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CSK C-terminal Src kinase decreases expression ISO Cyclophosphamide results in decreased expression of CSK mRNA CTD PMID:21041162 NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,057...74,803,198
JBrowse link
G CST7 cystatin F decreases expression EXP Cyclophosphamide results in decreased expression of CST7 mRNA CTD PMID:17403535 NCBI chr20:24,949,269...24,959,928
Ensembl chr20:24,949,269...24,959,928
JBrowse link
G CSTA cystatin A decreases expression EXP Cyclophosphamide metabolite results in decreased expression of CSTA mRNA CTD PMID:24356939 NCBI chr 3:122,325,248...122,341,969
Ensembl chr 3:122,325,248...122,341,969
JBrowse link
G CTH cystathionine gamma-lyase increases expression ISO Cyclophosphamide results in increased expression of CTH protein CTD PMID:29129814 NCBI chr 1:70,411,268...70,441,949
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G CTNNBIP1 catenin beta interacting protein 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CTNNBIP1 mRNA CTD PMID:16322899 NCBI chr 1:9,848,276...9,910,322
Ensembl chr 1:9,848,276...9,910,336
JBrowse link
G CTNND2 catenin delta 2 multiple interactions EXP CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:10,971,836...11,904,446
Ensembl chr 5:10,971,836...11,904,446
JBrowse link
G CTSD cathepsin D multiple interactions
increases activity
ISO [Cyclophosphamide co-treated with Mecamylamine] results in increased expression of CTSD mRNA
Cyclophosphamide results in increased activity of CTSD protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]
CTD PMID:18433785 PMID:25451569 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CTSH cathepsin H increases expression EXP Cyclophosphamide results in increased expression of CTSH mRNA CTD PMID:17403535 NCBI chr15:78,921,058...78,945,089
Ensembl chr15:78,921,058...78,949,574
JBrowse link
G CTSL cathepsin L increases expression
decreases expression
multiple interactions
EXP
ISO
Cyclophosphamide results in increased expression of CTSL mRNA
Cyclophosphamide results in decreased expression of CTSL mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of CTSL mRNA]
CTD PMID:17403535 PMID:30760223 NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,726,109...87,731,469
Ensembl chr 9:87,726,109...87,731,469
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 increases expression ISO Cyclophosphamide results in increased expression of CX3CL1 protein CTD PMID:16651033 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 increases expression ISO Cyclophosphamide results in increased expression of CX3CR1 protein CTD PMID:16651033 NCBI chr 3:39,263,494...39,281,735
Ensembl chr 3:39,263,494...39,281,735
Ensembl chr 3:39,263,494...39,281,735
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 increases expression
affects expression
multiple interactions
ISO Cyclophosphamide results in increased expression of CXCL1 protein
Cyclophosphamide affects the expression of CXCL3 mRNA
VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of CXCL1 protein]
Cyclophosphamide results in increased expression of CXCL1 mRNA; Cyclophosphamide results in increased expression of CXCL1 protein
CTD PMID:15331540 PMID:18483878 PMID:18848347 PMID:18957084 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 affects expression
increases expression
increases response to substance
ISO Cyclophosphamide affects the expression of CXCL10 mRNA
Cyclophosphamide results in increased expression of CXCL10 protein
CXCL10 protein results in increased susceptibility to Cyclophosphamide
CTD PMID:18957084 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 increases expression ISO Cyclophosphamide results in increased expression of CXCL11 protein CTD PMID:18957084 NCBI chr 4:76,033,682...76,036,070
Ensembl chr 4:76,033,682...76,041,415
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 affects expression
increases expression
ISO Cyclophosphamide affects the expression of CXCL12 mRNA
Cyclophosphamide results in increased expression of CXCL12 mRNA; Cyclophosphamide results in increased expression of CXCL12 protein
CTD PMID:12624490 PMID:16337237 PMID:19066630 PMID:20032115 NCBI chr10:44,292,088...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP
ISO
Cyclophosphamide results in increased expression of CXCL8 mRNA
Cyclophosphamide results in increased expression of CXCL5 mRNA
CTD PMID:15331540 PMID:29594315 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 affects expression
decreases expression
increases expression
ISO Cyclophosphamide affects the expression of CXCL9 mRNA
Cyclophosphamide results in decreased expression of CXCL9 protein
Cyclophosphamide results in increased expression of CXCL9 mRNA; Cyclophosphamide results in increased expression of CXCL9 protein
CTD PMID:15331540 PMID:18957084 PMID:21041162 PMID:21880982 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 multiple interactions
increases expression
decreases expression
affects localization
ISO Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein]
Cyclophosphamide results in increased expression of CXCR4 mRNA; Cyclophosphamide results in increased expression of CXCR4 protein
Cyclophosphamide results in decreased expression of CXCR4 mRNA
Cyclophosphamide affects the localization of CXCR4 protein
CTD PMID:19066630 PMID:20032115 PMID:21041162 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G CXCR6 C-X-C motif chemokine receptor 6 increases expression ISO Cyclophosphamide results in increased expression of CXCR6 mRNA CTD PMID:21041162 NCBI chr 3:45,940,915...45,948,351
Ensembl chr 3:45,940,933...45,948,351
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity ISO Cyclophosphamide results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity ISO Cyclophosphamide results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 decreases expression EXP Cyclophosphamide results in decreased expression of CYP1B1 mRNA CTD PMID:12167460 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP2A7 cytochrome P450 family 2 subfamily A member 7 decreases activity ISO Cyclophosphamide results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr19:40,875,439...40,885,951
Ensembl chr19:40,875,439...40,882,752
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions
increases metabolic processing
increases expression
increases activity
increases hydroxylation
increases response to substance
affects hydroxylation
EXP
ISO
[Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CYP2B6 mRNA; Cyclophosphamide results in decreased expression of and results in decreased activity of CYP2B6 protein; CYP2B6 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide; CYP2B6 protein results in increased metabolism of and results in increased susceptibility to Cyclophosphamide; POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
CYP2B6 protein results in increased metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2B10 mRNA
CYP2B6 protein results in increased activity of Cyclophosphamide
CYP2B6 protein results in increased hydroxylation of Cyclophosphamide
CYP2B6 protein results in increased susceptibility to Cyclophosphamide; CYP2B6 results in increased susceptibility to Cyclophosphamide
CYP2B6 intron polymorphism affects the hydroxylation of Cyclophosphamide; CYP2B6 promoter polymorphism affects the hydroxylation of Cyclophosphamide
CTD PMID:9766669 PMID:10919648 PMID:11389073 PMID:11723234 PMID:12498089 PMID:12872138 PMID:15248218 PMID:15769884 PMID:16183265 PMID:16322899 PMID:17041008 PMID:17502835 PMID:18212249 PMID:18633247 PMID:24819615 PMID:25860621 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 increases activity
increases response to substance
multiple interactions
EXP CYP2C18 results in increased activity of Cyclophosphamide
CYP2C18 results in increased susceptibility to Cyclophosphamide
POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]
CTD PMID:9241661 PMID:9766669 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases metabolic processing
increases hydroxylation
increases response to substance
increases metabolic processing
multiple interactions
increases activity
EXP
ISO
CYP2C19 gene polymorphism results in decreased metabolism of Cyclophosphamide
CYP2C19 protein results in increased hydroxylation of Cyclophosphamide
CYP2C19 protein results in increased susceptibility to Cyclophosphamide
CYP2C6V1 results in increased metabolism of Cyclophosphamide
[CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide; [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein; CYP2C19 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide
CYP2C19 results in increased activity of Cyclophosphamide
CYP2C19 protein results in increased metabolism of Cyclophosphamide
CTD PMID:9241661 PMID:15248218 PMID:16116487 PMID:20566340 PMID:30500380 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 increases activity
increases expression
EXP
ISO
CYP2C8 results in increased activity of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2C29 mRNA
CTD PMID:9241661 PMID:24819615 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 increases response to substance
decreases activity
increases metabolic processing
multiple interactions
increases activity
EXP
ISO
CYP2C9 protein results in increased susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased activity of CYP2C9 protein
CYP2C9 protein results in increased metabolism of Cyclophosphamide
[GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]; Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased susceptibility to Cyclophosphamide]
CYP2C9 results in increased activity of Cyclophosphamide
CTD PMID:9241661 PMID:10991840 PMID:11377097 PMID:18420780 PMID:24819615 PMID:28744217 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 increases metabolic processing EXP CYP2D6 protein results in increased metabolism of Cyclophosphamide CTD PMID:11377097 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,881
Ensembl chr22:42,126,499...42,130,881
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 increases metabolic processing ISO CYP2E1 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 increases expression
increases hydroxylation
increases response to substance
increases metabolic processing
affects metabolic processing
affects response to substance
multiple interactions
EXP Cyclophosphamide results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased hydroxylation of Cyclophosphamide
CYP3A4 protein results in increased susceptibility to Cyclophosphamide
CYP3A4 protein results in increased metabolism of Cyclophosphamide
CYP3A4 protein affects the metabolism of Cyclophosphamide
CYP3A4 gene polymorphism affects the susceptibility to Cyclophosphamide
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [CYP3A4 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide; [CYP3A4 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein; CYP3A4 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]; CYP3A4 protein results in increased metabolism of and results in increased susceptibility to Cyclophosphamide
CTD PMID:11377097 PMID:16087946 PMID:17041008 PMID:18839173 PMID:25860621 PMID:26718876 PMID:30500380 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 affects metabolic processing
increases expression
multiple interactions
affects response to substance
EXP
ISO
CYP3A5 protein affects the metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP3A13 mRNA
CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
CYP3A5 gene polymorphism affects the susceptibility to Cyclophosphamide
CTD PMID:16087946 PMID:24819615 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,998
JBrowse link
G DCN decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G DDB1 damage specific DNA binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of DDB1 mRNA CTD PMID:11056294 NCBI chr11:61,299,451...61,333,105
Ensembl chr11:61,299,451...61,342,596
JBrowse link
G DDIT3 DNA damage inducible transcript 3 affects expression
increases expression
multiple interactions
decreases expression
ISO
EXP
Cyclophosphamide affects the expression of DDIT3 mRNA
Cyclophosphamide results in increased expression of DDIT3 mRNA; Cyclophosphamide results in increased expression of DDIT3 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]
Cyclophosphamide metabolite results in decreased expression of DDIT3 mRNA
CTD PMID:18246545 PMID:24356939 PMID:32197949 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DDIT4 DNA damage inducible transcript 4 affects response to substance EXP DDIT4 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,924...72,276,036
Ensembl chr10:72,273,924...72,276,036
JBrowse link
G DEAF1 DEAF1 transcription factor decreases expression ISO Cyclophosphamide results in decreased expression of DEAF1 mRNA CTD PMID:27281708 NCBI chr11:644,220...707,083
Ensembl chr11:644,233...706,715
JBrowse link
G DLC1 DLC1 Rho GTPase activating protein increases expression EXP Cyclophosphamide results in increased expression of DLC1 mRNA CTD PMID:17403535 NCBI chr 8:13,083,361...13,604,620
Ensembl chr 8:13,083,361...13,604,610
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 affects expression
increases expression
ISO
EXP
Cyclophosphamide affects the expression of DNAJB1 mRNA
Cyclophosphamide metabolite results in increased expression of DNAJB1 mRNA
CTD PMID:18246545 PMID:24356939 NCBI chr19:14,514,769...14,530,597
Ensembl chr19:14,514,769...14,529,770
Ensembl chr19:14,514,769...14,529,770
JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP Cyclophosphamide metabolite results in increased expression of DNAJB4 mRNA CTD PMID:24356939 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 increases expression EXP Cyclophosphamide results in increased expression of DNAJB6 protein CTD PMID:17475930 NCBI chr 7:157,337,004...157,417,439
Ensembl chr 7:157,335,381...157,417,439
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions
increases expression
decreases methylation
EXP Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in increased expression of DNMT1 protein
Cyclophosphamide results in decreased methylation of DNMT1 protein
CTD PMID:22007908 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,345...10,231,286
Ensembl chr19:10,133,345...10,231,286
JBrowse link
G DNTT DNA nucleotidylexotransferase decreases expression ISO Cyclophosphamide results in decreased expression of DNTT mRNA CTD PMID:21041162 NCBI chr10:96,304,434...96,338,564
Ensembl chr10:96,304,409...96,338,564
JBrowse link
G DPF3 double PHD fingers 3 decreases expression ISO Cyclophosphamide results in decreased expression of DPF3 mRNA CTD PMID:27281708 NCBI chr14:72,609,034...72,894,101
Ensembl chr14:72,619,296...72,894,116
JBrowse link
G DPYSL4 dihydropyrimidinase like 4 increases expression EXP Cyclophosphamide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr10:132,184,983...132,205,759
Ensembl chr10:132,186,948...132,205,759
JBrowse link
G DRD1 dopamine receptor D1 affects binding ISO Cyclophosphamide binds to DRD1 protein CTD PMID:11180191 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
JBrowse link
G DRD2 dopamine receptor D2 affects binding ISO Cyclophosphamide binds to DRD2 protein CTD PMID:11180191 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G DUSP10 dual specificity phosphatase 10 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of DUSP10 mRNA CTD PMID:24356939 NCBI chr 1:221,701,424...221,742,091
Ensembl chr 1:221,701,424...221,742,089
JBrowse link
G DUSP2 dual specificity phosphatase 2 decreases expression ISO Cyclophosphamide results in decreased expression of DUSP2 mRNA CTD PMID:21041162 NCBI chr 2:96,143,166...96,145,468
Ensembl chr 2:96,143,169...96,145,440
JBrowse link
G DZIP1 DAZ interacting zinc finger protein 1 increases expression EXP Cyclophosphamide results in increased expression of DZIP1 mRNA CTD PMID:17403535 NCBI chr13:95,578,202...95,644,706
Ensembl chr13:95,578,202...95,644,706
Ensembl chr13:95,578,202...95,644,706
JBrowse link
G E2F3 E2F transcription factor 3 multiple interactions EXP E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714
JBrowse link
G EDA2R ectodysplasin A2 receptor increases expression EXP Cyclophosphamide results in increased expression of EDA2R mRNA CTD PMID:21527772 NCBI chr  X:66,594,384...66,639,303
Ensembl chr  X:66,595,637...66,639,298
JBrowse link
G EDN1 endothelin 1 increases expression EXP Cyclophosphamide results in increased expression of EDN1 protein CTD PMID:17562616 PMID:18548196 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDNRB endothelin receptor type B increases expression EXP Cyclophosphamide results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr13:77,895,481...77,975,527
Ensembl chr13:77,895,481...77,975,529
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 decreases expression ISO Cyclophosphamide results in decreased expression of EEF2 mRNA CTD PMID:18246545 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGR1 early growth response 1 increases expression
multiple interactions
decreases expression
EXP
ISO
Cyclophosphamide results in increased expression of EGR1 mRNA
Cyclophosphamide results in increased expression of EGR1 protein
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein
Cyclophosphamide results in decreased expression of EGR1 mRNA
CTD PMID:7498375 PMID:9776515 PMID:21041162 PMID:21527772 PMID:29129814 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EGR2 early growth response 2 decreases expression ISO Cyclophosphamide results in decreased expression of EGR2 mRNA CTD PMID:21041162 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,919,900
JBrowse link
G EGR4 early growth response 4 decreases expression ISO Cyclophosphamide results in decreased expression of EGR4 mRNA CTD PMID:27281708 NCBI chr 2:73,290,929...73,293,548
Ensembl chr 2:73,290,929...73,293,701
JBrowse link
G EIF1AX eukaryotic translation initiation factor 1A X-linked multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF1AX mRNA CTD PMID:16322899 NCBI chr  X:20,124,525...20,141,838
Ensembl chr  X:20,124,525...20,141,838
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
ISO sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein] CTD PMID:32197949 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF4EBP1 mRNA CTD PMID:16322899 NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
JBrowse link
G ELOVL2 ELOVL fatty acid elongase 2 affects response to substance EXP ELOVL2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:10,980,759...11,044,305
Ensembl chr 6:10,980,759...11,044,305
JBrowse link
G EMP1 epithelial membrane protein 1 increases expression EXP Cyclophosphamide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr12:13,196,726...13,219,941
Ensembl chr12:13,196,723...13,219,941
JBrowse link
G EMP3 epithelial membrane protein 3 increases expression EXP Cyclophosphamide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr19:48,325,504...48,330,554
Ensembl chr19:48,321,509...48,330,553
JBrowse link
G EPB41L2 erythrocyte membrane protein band 4.1 like 2 decreases expression EXP Cyclophosphamide results in decreased expression of EPB41L2 mRNA CTD PMID:17403535 NCBI chr 6:130,827,955...131,063,251
Ensembl chr 6:130,839,347...131,063,322
JBrowse link
G EPHX1 epoxide hydrolase 1 affects expression
increases expression
ISO Cyclophosphamide affects the expression of EPHX1 mRNA
Cyclophosphamide results in increased expression of EPHX1 mRNA
CTD PMID:18246545 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,092...225,845,563
Ensembl chr 1:225,810,092...225,845,563
JBrowse link
G EPO erythropoietin multiple interactions
increases response to substance
decreases expression
ISO angelicae sinensis extract inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]; Astragali compound inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]
EPO protein results in increased susceptibility to Cyclophosphamide
CTD PMID:11245434 PMID:19627214 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 increases expression ISO Cyclophosphamide results in increased expression of ERAP1 mRNA CTD PMID:27281708 NCBI chr 5:96,760,273...96,935,983
Ensembl chr 5:96,760,810...96,808,100
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP ERBB2 affects the susceptibility to [Doxorubicin co-treated with Cyclophosphamide co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; ERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin] CTD PMID:9816327 PMID:15834928 PMID:15940066 PMID:16446318 PMID:16682728 PMID:17010609 NCBI chr17:39,688,094...39,728,660
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit affects expression ISO Cyclophosphamide affects the expression of ERCC1 mRNA CTD PMID:11906922 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,333...45,478,828
Ensembl chr19:45,407,333...45,478,828
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit affects expression
increases expression
multiple interactions
ISO Cyclophosphamide affects the expression of ERCC2 mRNA
Cyclophosphamide results in increased expression of ERCC2 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of ERCC2 mRNA]
CTD PMID:11906922 PMID:30760223 NCBI chr19:45,349,837...45,370,647
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ERG ETS transcription factor ERG increases expression EXP Cyclophosphamide results in increased expression of ERG mRNA CTD PMID:17403535 NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases phosphorylation
ISO sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein] CTD PMID:32197949 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,142...64,130,819
Ensembl chr17:64,039,142...64,130,819
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR1 mRNA CTD PMID:16322899 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR2 mRNA CTD PMID:16322899 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G ESRRA estrogen related receptor alpha decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of ESRRA mRNA
Cyclophosphamide results in increased expression of ESRRA mRNA
CTD PMID:27281708 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743
Ensembl chr11:64,305,497...64,316,743
JBrowse link
G EVI2A ecotropic viral integration site 2A decreases expression EXP Cyclophosphamide metabolite results in decreased expression of EVI2A mRNA CTD PMID:24356939 NCBI chr17:31,316,410...31,321,622
Ensembl chr17:31,316,410...31,321,749
Ensembl chr17:31,316,410...31,321,749
JBrowse link
G F2RL1 F2R like trypsin receptor 1 increases expression ISO Cyclophosphamide results in increased expression of F2RL1 protein CTD PMID:15643279 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315
JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 increases expression ISO Cyclophosphamide results in increased expression of F2RL2 protein CTD PMID:15643279 NCBI chr 5:76,615,482...76,623,403
Ensembl chr 5:76,615,482...76,623,413
JBrowse link
G F2RL3 F2R like thrombin or trypsin receptor 3 increases expression ISO Cyclophosphamide results in increased expression of F2RL3 protein CTD PMID:15643279 NCBI chr19:16,888,999...16,892,606
Ensembl chr19:16,888,999...16,892,606
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression EXP Cyclophosphamide results in decreased expression of F3 mRNA CTD PMID:17403535 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
JBrowse link
G FAM107B family with sequence similarity 107 member B decreases expression EXP Cyclophosphamide metabolite results in decreased expression of FAM107B mRNA CTD PMID:24356939 NCBI chr10:14,518,557...14,774,897
Ensembl chr10:14,518,557...14,774,897
JBrowse link
G FAM234B family with sequence similarity 234 member B multiple interactions EXP FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:13,044,381...13,083,449
Ensembl chr12:13,044,381...13,142,521
JBrowse link
G FAS Fas cell surface death receptor multiple interactions
decreases expression
increases expression
EXP
ISO
[Cyclophosphamide co-treated with cacalol] results in decreased expression of FAS protein; [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FAS
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of FAS mRNA]
Cyclophosphamide metabolite results in decreased expression of FAS mRNA
Cyclophosphamide results in increased expression of FAS mRNA; Cyclophosphamide results in increased expression of FAS protein
CTD PMID:10393266 PMID:16166447 PMID:20665104 PMID:24356939 PMID:25446862 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand multiple interactions EXP [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FASLG CTD PMID:16166447 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FAU FAU ubiquitin like and ribosomal protein S30 fusion increases expression ISO Cyclophosphamide results in increased expression of FAU mRNA CTD PMID:11599041 NCBI chr11:65,120,630...65,122,134
Ensembl chr11:65,120,630...65,122,177
JBrowse link
G FBXO40 F-box protein 40 increases expression ISO Cyclophosphamide results in increased expression of FBXO40 mRNA CTD PMID:27281708 NCBI chr 3:121,593,379...121,630,295
Ensembl chr 3:121,593,379...121,630,295
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 increases expression EXP Cyclophosphamide results in increased expression of FBXW7 mRNA CTD PMID:29445054 NCBI chr 4:152,320,544...152,536,873
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig increases expression ISO Cyclophosphamide results in increased expression of FCER1G mRNA CTD PMID:21041162 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa increases expression ISO Cyclophosphamide results in increased expression of FCGR3 mRNA CTD PMID:21041162 NCBI chr 1:161,505,430...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FCGRT Fc fragment of IgG receptor and transporter increases expression ISO Cyclophosphamide results in increased expression of FCGRT mRNA CTD PMID:21041162 NCBI chr19:49,512,661...49,526,428
Ensembl chr19:49,506,816...49,526,428
JBrowse link
G FHL1 four and a half LIM domains 1 increases expression ISO Cyclophosphamide results in increased expression of FHL1 mRNA CTD PMID:23558518 NCBI chr  X:136,146,702...136,211,359
Ensembl chr  X:136,146,702...136,211,359
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B affects response to substance EXP FKBP1B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:24,033,205...24,067,743
Ensembl chr 2:24,049,701...24,063,681
JBrowse link
G FKBPL FKBP prolyl isomerase like increases expression EXP Cyclophosphamide results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr 6:32,128,707...32,130,288
Ensembl chr 6:32,128,707...32,130,288
JBrowse link
G FLNC filamin C increases expression EXP Cyclophosphamide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,377...128,859,274
Ensembl chr 7:128,830,377...128,859,274
JBrowse link
G FLT3LG fms related receptor tyrosine kinase 3 ligand affects expression ISO Cyclophosphamide affects the expression of FLT3L mRNA CTD PMID:12624490 NCBI chr19:49,474,172...49,487,037
Ensembl chr19:49,474,207...49,486,231
JBrowse link
G FNDC3B fibronectin type III domain containing 3B affects response to substance EXP FNDC3B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 3:172,039,578...172,401,669
Ensembl chr 3:172,039,578...172,401,669
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]
Cyclophosphamide results in increased expression of FOS protein
alfuzosin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]
CTD PMID:7498375 PMID:8801120 PMID:8808730 PMID:9776515 PMID:10749792 PMID:15099680 PMID:15217452 PMID:17240043 PMID:18093676 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOXP3 forkhead box P3 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of FOXP3 mRNA; Cyclophosphamide results in decreased expression of FOXP3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]
CTD PMID:15591121 PMID:32151603 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G FOXP4 forkhead box P4 decreases expression ISO Cyclophosphamide results in decreased expression of FOXP4 mRNA CTD PMID:27281708 NCBI chr 6:41,546,381...41,602,384
Ensembl chr 6:41,546,426...41,602,384
Ensembl chr 6:41,546,426...41,602,384
JBrowse link
G FPR2 formyl peptide receptor 2 increases expression ISO Cyclophosphamide results in increased expression of FPR2 mRNA CTD PMID:15331540 NCBI chr19:51,752,026...51,770,531
Ensembl chr19:51,752,026...51,770,531
JBrowse link
G FSCN1 fascin actin-bundling protein 1 increases expression EXP Cyclophosphamide results in increased expression of FSCN1 mRNA CTD PMID:17403535 NCBI chr 7:5,592,816...5,606,655
Ensembl chr 7:5,592,816...5,606,655
JBrowse link
G FSHB follicle stimulating hormone subunit beta increases expression
multiple interactions
decreases secretion
EXP
ISO
Cyclophosphamide results in increased expression of FSHB protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]
CTD PMID:6788612 PMID:25446862 PMID:32197949 NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,016...30,235,261
Ensembl chr11:30,231,016...30,235,261
JBrowse link
G FSHR follicle stimulating hormone receptor decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of FSHR mRNA
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of FSHR mRNA]
CTD PMID:31557371 NCBI chr 2:48,953,161...49,154,527
Ensembl chr 2:48,962,157...49,154,527
Ensembl chr 2:48,962,157...49,154,527
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase increases expression EXP Cyclophosphamide results in increased expression of FYN mRNA CTD PMID:17403535 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G G3BP1 G3BP stress granule assembly factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of G3BP1 mRNA CTD PMID:21041162 NCBI chr 5:151,771,954...151,812,785
Ensembl chr 5:151,771,045...151,812,785
Ensembl chr 5:151,771,045...151,812,785
JBrowse link
G G6PC2 glucose-6-phosphatase catalytic subunit 2 decreases expression ISO Cyclophosphamide results in decreased expression of G6PC2 mRNA CTD PMID:15331540 NCBI chr 2:168,901,223...168,910,000
Ensembl chr 2:168,901,291...168,910,000
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression
affects expression
ISO
EXP
Cyclophosphamide results in increased expression of GADD45A mRNA
Cyclophosphamide affects the expression of GADD45A mRNA
CTD PMID:18246545 PMID:29445054 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GAL galanin and GMAP prepropeptide affects expression
increases expression
ISO Cyclophosphamide affects the expression of GAL mRNA; Cyclophosphamide affects the expression of GAL protein
Cyclophosphamide results in increased expression of GAL mRNA
CTD PMID:16491427 PMID:17335920 PMID:18563302 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
JBrowse link
G GALC galactosylceramidase affects response to substance EXP GALC protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr14:87,933,014...87,993,665
Ensembl chr14:87,837,820...87,993,665
JBrowse link
G GAMT guanidinoacetate N-methyltransferase multiple interactions EXP GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570
JBrowse link
G GAP43 growth associated protein 43 increases expression ISO Cyclophosphamide results in increased expression of GAP43 protein CTD PMID:9486479 PMID:10536274 NCBI chr 3:115,623,510...115,721,485
Ensembl chr 3:115,623,324...115,721,490
Ensembl chr 3:115,623,324...115,721,490
JBrowse link
G GAS2 growth arrest specific 2 increases expression EXP Cyclophosphamide results in increased expression of GAS2 protein CTD PMID:17475930 NCBI chr11:22,627,758...22,885,930
Ensembl chr11:22,625,509...22,813,055
JBrowse link
G GATA3 GATA binding protein 3 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of GATA3 mRNA; Cyclophosphamide results in decreased expression of GATA3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]
CTD PMID:21041162 PMID:32151603 NCBI chr10:8,045,420...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GBP1 guanylate binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of GBP1 mRNA CTD PMID:21621594 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,052,319...89,065,230
Ensembl chr 1:89,052,319...89,065,230
JBrowse link
G GBP4 guanylate binding protein 4 increases expression ISO Cyclophosphamide results in increased expression of GBP3 mRNA CTD PMID:15331540 NCBI chr 1:89,181,144...89,198,942
Ensembl chr 1:89,181,144...89,198,942
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
decreases expression
ISO Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]
Cyclophosphamide results in decreased expression of GCLC mRNA; Cyclophosphamide results in decreased expression of GCLC protein
CTD PMID:27633142 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GDNF glial cell derived neurotrophic factor increases expression ISO Cyclophosphamide results in increased expression of GDNF mRNA CTD PMID:10683293 NCBI chr 5:37,812,677...37,840,044
Ensembl chr 5:37,812,677...37,840,041
JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle increases expression ISO Cyclophosphamide results in increased expression of GEM mRNA CTD PMID:21041162 NCBI chr 8:94,249,249...94,262,345
Ensembl chr 8:94,249,253...94,262,350
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor decreases expression ISO Cyclophosphamide results in decreased expression of GFI1 mRNA CTD PMID:21041162 NCBI chr 1:92,473,043...92,486,925
Ensembl chr 1:92,473,043...92,486,925
JBrowse link
G GFRA1 GDNF family receptor alpha 1 multiple interactions EXP GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:116,056,925...116,274,705
Ensembl chr10:116,056,925...116,273,467
Ensembl chr10:116,056,925...116,273,467
JBrowse link
G GIMAP4 GTPase, IMAP family member 4 decreases expression ISO Cyclophosphamide results in decreased expression of GIMAP4 mRNA CTD PMID:27466211 NCBI chr 7:150,567,390...150,573,953
Ensembl chr 7:150,567,369...150,573,953
JBrowse link
G GJA1 gap junction protein alpha 1 affects expression ISO Cyclophosphamide affects the expression of GJA1 mRNA CTD PMID:10859244 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJB1 gap junction protein beta 1 decreases expression ISO Cyclophosphamide results in decreased expression of GJB1 mRNA CTD PMID:21621594 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G GLIS1 GLIS family zinc finger 1 decreases expression ISO Cyclophosphamide results in decreased expression of GLIS1 mRNA CTD PMID:27281708 NCBI chr 1:53,506,237...53,739,171
Ensembl chr 1:53,506,237...53,738,106
JBrowse link
G GLOD4 glyoxalase domain containing 4 decreases expression EXP Cyclophosphamide results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr17:759,321...789,830
Ensembl chr17:757,097...783,390
JBrowse link
G GLRB glycine receptor beta increases expression EXP Cyclophosphamide results in increased expression of GLRB mRNA CTD PMID:17403535 NCBI chr 4:157,076,146...157,172,090
Ensembl chr 4:157,076,125...157,172,090
JBrowse link
G GLS glutaminase increases expression
affects response to substance
EXP Cyclophosphamide results in increased expression of GLS mRNA
GLS protein affects the susceptibility to Cyclophosphamide
CTD PMID:16217747 PMID:21527772 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
JBrowse link
G GNG12 G protein subunit gamma 12 increases expression EXP Cyclophosphamide results in increased expression of GNG12 mRNA CTD PMID:17403535 NCBI chr 1:67,701,475...67,833,467
Ensembl chr 1:67,701,475...67,833,467
JBrowse link
G GPATCH8 G-patch domain containing 8 increases expression ISO Cyclophosphamide results in increased expression of GPATCH8 mRNA CTD PMID:27281708 NCBI chr17:44,395,277...44,503,589
Ensembl chr17:44,395,281...44,503,430
JBrowse link
G GPR137B G protein-coupled receptor 137B increases expression EXP Cyclophosphamide results in increased expression of GPR137B mRNA CTD PMID:21527772 NCBI chr 1:236,142,529...236,213,535
Ensembl chr 1:236,142,505...236,221,865
JBrowse link
G GPR18 G protein-coupled receptor 18 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of GPR18 mRNA CTD PMID:24356939 NCBI chr13:99,254,713...99,262,498
Ensembl chr13:99,254,714...99,261,744
Ensembl chr13:99,254,714...99,261,744
JBrowse link
G GPR20 G protein-coupled receptor 20 increases expression EXP Cyclophosphamide results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr 8:141,356,470...141,367,286
Ensembl chr 8:141,356,470...141,367,286
JBrowse link
G GPT glutamic--pyruvic transaminase increases expression
increases activity
multiple interactions
ISO Cyclophosphamide results in increased expression of GPT protein
Cyclophosphamide results in increased activity of GPT protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]
Rutin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Cyclophosphamide results in increased expression of GPT protein]
CTD PMID:25753322 PMID:25779342 PMID:29753871 PMID:30506662 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of GPT2 mRNA CTD PMID:24356939 NCBI chr16:46,884,362...46,931,289
Ensembl chr16:46,884,362...46,931,289
JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of GPX1 mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of GPX1 mRNA]
CTD PMID:23542512 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,358
Ensembl chr 3:49,357,176...49,358,358
JBrowse link
G GPX3 glutathione peroxidase 3 increases expression ISO Cyclophosphamide results in increased expression of GPX3 mRNA CTD PMID:21041162 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,438...151,028,992
JBrowse link
G GPX4 glutathione peroxidase 4 increases expression EXP Cyclophosphamide results in increased expression of GPX4 protein CTD PMID:17475930 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,926...1,106,791
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases activity
ISO [[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein; Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
CTD PMID:12114195 PMID:21772021 PMID:23542512 PMID:25446862 PMID:25753322 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTA1 glutathione S-transferase alpha 1 multiple interactions EXP GSTA1 protein affects the metabolism of [Cyclophosphamide metabolite co-treated with Glutathione] CTD PMID:12516103 NCBI chr 6:52,791,371...52,803,827
Ensembl chr 6:52,791,371...52,803,860
JBrowse link
G GSTM1 glutathione S-transferase mu 1 multiple interactions EXP [GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]; GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946 PMID:28744217 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTM2 glutathione S-transferase mu 2 decreases expression ISO Cyclophosphamide results in decreased expression of GSTM2 mRNA CTD PMID:11906922 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTP1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
affects response to substance
increases expression
EXP
ISO
GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]
GSTP1 protein results in decreased susceptibility to Cyclophosphamide
GSTP1 protein affects the susceptibility to Cyclophosphamide
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
Cyclophosphamide results in increased expression of GSTP1 mRNA; Cyclophosphamide results in increased expression of GSTP1 protein
CTD PMID:10954901 PMID:12791655 PMID:16141653 PMID:16242832 PMID:19696094 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GTF2B general transcription factor IIB increases expression ISO Cyclophosphamide results in increased expression of GTF2B mRNA CTD PMID:27281708 NCBI chr 1:88,852,633...88,891,944
Ensembl chr 1:88,852,633...88,891,944
JBrowse link
G GTF3C1 general transcription factor IIIC subunit 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of GTF3C1 mRNA CTD PMID:16322899 NCBI chr16:27,460,613...27,549,922
Ensembl chr16:27,459,555...27,549,913
JBrowse link
G GUSB glucuronidase beta decreases expression
increases activity
multiple interactions
ISO Cyclophosphamide results in decreased expression of GUSB protein
Cyclophosphamide results in increased activity of GUSB protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]
CTD PMID:17686619 PMID:25451569 NCBI chr 7:65,960,684...65,982,230
Ensembl chr 7:65,960,684...65,982,215
JBrowse link
G GZMA granzyme A decreases expression ISO Cyclophosphamide results in decreased expression of GZMA mRNA CTD PMID:21041162 NCBI chr 5:55,102,646...55,110,252
Ensembl chr 5:55,102,646...55,110,252
JBrowse link
G GZMB granzyme B increases expression ISO Cyclophosphamide results in increased expression of GZMB mRNA CTD PMID:15331540 NCBI chr14:24,630,954...24,634,190
Ensembl chr14:24,630,954...24,634,267
JBrowse link
G H2AX H2A.X variant histone increases phosphorylation EXP Cyclophosphamide results in increased phosphorylation of H2AX protein CTD PMID:32482060 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,854...119,095,467
JBrowse link
G HCRT hypocretin neuropeptide precursor affects localization
decreases expression
ISO Cyclophosphamide affects the localization of HCRT protein
Cyclophosphamide results in decreased expression of HCRT mRNA
CTD PMID:17881193 PMID:19666069 NCBI chr17:42,184,060...42,185,452
Ensembl chr17:42,184,060...42,185,452
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha increases expression ISO Cyclophosphamide results in increased expression of HIF1A mRNA CTD PMID:15331540 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HINFP histone H4 transcription factor decreases expression ISO Cyclophosphamide results in decreased expression of HINFP mRNA CTD PMID:27281708 NCBI chr11:119,121,577...119,136,059
Ensembl chr11:119,121,580...119,136,059
JBrowse link
G HLA-F major histocompatibility complex, class I, F increases expression EXP Cyclophosphamide results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr 6:29,723,434...29,740,355
Ensembl chr 6:29,722,775...29,738,528
JBrowse link
G HM13 histocompatibility minor 13 decreases expression ISO Cyclophosphamide results in decreased expression of H13 mRNA CTD PMID:15331540 NCBI chr20:31,514,442...31,569,543
Ensembl chr20:31,514,410...31,577,923
JBrowse link
G HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Cyclophosphamide metabolite results in increased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr 5:43,287,470...43,313,477
Ensembl chr 5:43,287,470...43,313,512
JBrowse link
G HMOX1 heme oxygenase 1 affects expression
decreases expression
multiple interactions
increases expression
ISO
EXP
Cyclophosphamide affects the expression of HMOX1 mRNA
Cyclophosphamide results in decreased expression of HMOX1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; Hemin inhibits the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]
Cyclophosphamide results in increased expression of HMOX1 mRNA; Cyclophosphamide results in increased expression of HMOX1 protein
CTD PMID:11906922 PMID:17979934 PMID:18206168 PMID:18246545 PMID:19952508 PMID:20038455 PMID:20433640 PMID:32197949 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HMOX2 heme oxygenase 2 decreases expression ISO Cyclophosphamide results in decreased expression of HMOX2 mRNA CTD PMID:11906922 NCBI chr16:4,474,697...4,510,347
Ensembl chr16:4,474,690...4,510,347
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K increases expression EXP
ISO
Cyclophosphamide results in increased expression of HNRNPK protein
Cyclophosphamide results in increased expression of HNRNPK mRNA
CTD PMID:11599041 PMID:17475930 NCBI chr 9:83,968,083...83,980,630
Ensembl chr 9:83,968,083...83,980,616
JBrowse link
G HOXA1 homeobox A1 affects response to substance EXP HOXA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 7:27,092,993...27,096,000
Ensembl chr 7:27,093,313...27,095,996
Ensembl chr 7:27,093,313...27,095,996
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO Cyclophosphamide results in increased mutagenesis of HPRT1 gene CTD PMID:17116724 PMID:23677247 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Cyclophosphamide results in decreased expression of HSP90AA1 mRNA CTD PMID:11906922 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Cyclophosphamide results in decreased expression of HSP90AB1 mRNA CTD PMID:11906922 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888
JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of HSP90B1 mRNA
Cyclophosphamide results in increased expression of HSP90B1 mRNA
CTD PMID:11599041 PMID:11906922 NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,645
Ensembl chr12:103,930,107...103,953,645
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A affects expression
increases expression
ISO
EXP
Cyclophosphamide affects the expression of HSPA1A mRNA
Cyclophosphamide results in increased expression of HSPA1A mRNA; Cyclophosphamide results in increased expression of HSPA1A protein
CTD PMID:8917683 PMID:18246545 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B affects expression
increases expression
decreases expression
ISO
EXP
Cyclophosphamide affects the expression of HSPA1B mRNA
Cyclophosphamide metabolite results in increased expression of HSPA1B mRNA
Cyclophosphamide results in decreased expression of HSPA1B mRNA
CTD PMID:16141653 PMID:18246545 PMID:24356939 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA2 heat shock protein family A (Hsp70) member 2 affects response to substance
increases expression
EXP
ISO
HSPA2 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of HSPA2 mRNA
CTD PMID:11599041 PMID:16217747 NCBI chr14:64,535,905...64,543,237
Ensembl chr14:64,535,905...64,546,173
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 decreases expression
increases expression
ISO
EXP
Cyclophosphamide results in decreased expression of HSPA5 mRNA
Cyclophosphamide metabolite results in increased expression of HSPA5 mRNA
CTD PMID:11906922 PMID:24356939 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 affects response to substance EXP HSPA8 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr11:123,057,489...123,062,366
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Cyclophosphamide results in decreased expression of HSPA9 mRNA CTD PMID:11906922 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of HSPB1 mRNA
Cyclophosphamide results in increased expression of HSPB1 mRNA
CTD PMID:11599041 PMID:11906922 PMID:18246545 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Cyclophosphamide results in decreased expression of HSPD1 mRNA CTD PMID:11906922 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 decreases expression ISO Cyclophosphamide results in decreased expression of HSPE1 mRNA CTD PMID:11906922 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression EXP Cyclophosphamide metabolite results in increased expression of HSPH1 mRNA CTD PMID:24356939 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
JBrowse link
G HYLS1 HYLS1 centriolar and ciliogenesis associated decreases expression EXP Cyclophosphamide metabolite results in decreased expression of HYLS1 mRNA CTD PMID:24356939 NCBI chr11:125,883,614...125,900,646
Ensembl chr11:125,883,614...125,900,646
Ensembl chr11:125,883,614...125,900,646
JBrowse link
G HYOU1 hypoxia up-regulated 1 decreases expression ISO Cyclophosphamide results in decreased expression of HYOU1 mRNA CTD PMID:11906922 NCBI chr11:119,044,187...119,057,205
Ensembl chr11:119,044,188...119,057,227
JBrowse link
G ICA1 islet cell autoantigen 1 affects response to substance ISO ICA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:11751995 NCBI chr 7:8,113,184...8,262,687
Ensembl chr 7:8,113,184...8,262,687
JBrowse link
G ICAM1 intercellular adhesion molecule 1 affects response to substance ISO ICAM1 protein affects the susceptibility to Cyclophosphamide CTD PMID:11591119 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G ICAM3 intercellular adhesion molecule 3 decreases expression EXP Cyclophosphamide results in decreased expression of ICAM3 mRNA CTD PMID:17403535 NCBI chr19:10,333,776...10,339,624
Ensembl chr19:10,333,776...10,339,661
JBrowse link
G ID2 inhibitor of DNA binding 2 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of ID2 mRNA CTD PMID:24356939 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP Cyclophosphamide metabolite results in increased expression of IDI1 mRNA CTD PMID:24356939 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,170
Ensembl chr10:1,039,152...1,049,170
JBrowse link
G IER3 immediate early response 3 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of IER3 mRNA CTD PMID:24356939 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548
JBrowse link
G IER5 immediate early response 5 increases expression EXP Cyclophosphamide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr 1:181,088,700...181,092,900
Ensembl chr 1:181,088,700...181,092,900
JBrowse link
G IFI16 interferon gamma inducible protein 16 increases expression ISO Cyclophosphamide results in increased expression of IFI204 mRNA CTD PMID:21041162 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155
JBrowse link
G IFIT2 interferon induced protein with tetratricopeptide repeats 2 increases expression ISO Cyclophosphamide results in increased expression of IFIT2 mRNA CTD PMID:15331540 NCBI chr10:89,302,046...89,309,271
Ensembl chr10:89,283,694...89,309,271
JBrowse link
G IFNG interferon gamma affects expression
multiple interactions
decreases secretion
increases expression
decreases expression
ISO
EXP
Cyclophosphamide affects the expression of IFNG mRNA
[Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA
Cyclophosphamide results in decreased secretion of IFNG protein
Cyclophosphamide results in increased expression of IFNG mRNA
Cyclophosphamide results in decreased expression of IFNG mRNA
Cyclophosphamide results in increased expression of IFNG protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; IFNG protein inhibits the reaction [Cyclophosphamide results in increased abundance of Nitric Oxide]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]
CTD PMID:10607705 PMID:11006010 PMID:11014644 PMID:15331540 PMID:18848347 PMID:18957084 PMID:21068404 PMID:22842586 PMID:23395935 PMID:29594315 PMID:32151603 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IFNGR1 interferon gamma receptor 1 decreases expression ISO Cyclophosphamide results in decreased expression of IFNGR1 mRNA CTD PMID:21041162 NCBI chr 6:137,197,484...137,220,351
Ensembl chr 6:137,197,484...137,219,449
Ensembl chr 6:137,197,484...137,219,449
JBrowse link
G IFRD1 interferon related developmental regulator 1 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of IFRD1 mRNA CTD PMID:24356939 NCBI chr 7:112,423,174...112,477,203
Ensembl chr 7:112,422,887...112,481,017
Ensembl chr 7:112,422,887...112,481,017
JBrowse link
G IGF2BP3 insulin like growth factor 2 mRNA binding protein 3 affects response to substance EXP IGF2BP3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 7:23,310,209...23,470,674
Ensembl chr 7:23,310,209...23,470,491
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 affects response to substance
decreases expression
EXP
ISO
IGFBP3 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of IGFBP3 mRNA
CTD PMID:16141653 PMID:16217747 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 multiple interactions EXP IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725
JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 decreases expression ISO
EXP
Cyclophosphamide results in decreased expression of IGFBP5 mRNA CTD PMID:15331540 PMID:20849824 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
JBrowse link
G IGKC immunoglobulin kappa constant decreases expression ISO Cyclophosphamide results in decreased expression of IGKC mRNA CTD PMID:15331540 NCBI chr 2:88,857,361...88,857,683
Ensembl chr 2:88,857,161...88,857,683
JBrowse link
G IL10 interleukin 10 decreases expression
multiple interactions
increases expression
ISO Cyclophosphamide results in decreased expression of IL10 mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL10 protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]
Cyclophosphamide results in increased expression of IL10 mRNA
Cyclophosphamide results in increased expression of IL10 protein
CTD PMID:11014644 PMID:11948286 PMID:18848347 PMID:21068404 PMID:25451569 PMID:31651976 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL12A interleukin 12A multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:29228376 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
JBrowse link
G IL12B interleukin 12B affects expression
multiple interactions
increases expression
ISO Cyclophosphamide affects the expression of IL12B mRNA
[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]
Cyclophosphamide results in increased expression of IL12B mRNA
CTD PMID:15331540 PMID:18957084 PMID:22842586 PMID:29228376 NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,487
JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 increases expression ISO Cyclophosphamide results in increased expression of IL13RA1 mRNA CTD PMID:21041162 NCBI chr  X:118,726,954...118,794,533
Ensembl chr  X:118,727,133...118,794,535
JBrowse link
G IL15 interleukin 15 multiple interactions
decreases secretion
ISO (4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein] CTD PMID:23395935 NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
JBrowse link
G IL15RA interleukin 15 receptor subunit alpha increases expression ISO Cyclophosphamide results in increased expression of IL15RA mRNA CTD PMID:21041162 NCBI chr10:5,948,897...5,978,741
Ensembl chr10:5,943,639...5,978,187
JBrowse link
G IL16 interleukin 16 decreases expression ISO Cyclophosphamide results in decreased expression of IL16 mRNA CTD PMID:21041162 NCBI chr15:81,196,879...81,314,058
Ensembl chr15:81,159,575...81,314,058
JBrowse link
G IL17A interleukin 17A decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of IL17A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]
CTD PMID:21880982 PMID:32151603 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 increases expression ISO Cyclophosphamide results in increased expression of IL18 protein CTD PMID:18848347 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha increases expression
multiple interactions
affects response to substance
ISO
EXP
Cyclophosphamide results in increased expression of IL1A mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein
Cyclophosphamide results in increased expression of IL1A protein
IL1A promoter polymorphism affects the susceptibility to Cyclophosphamide
CTD PMID:15331540 PMID:16636934 PMID:18848347 PMID:31651976 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta increases expression
decreases expression
increases response to substance
multiple interactions
ISO Cyclophosphamide results in increased expression of IL1B mRNA; Cyclophosphamide results in increased expression of IL1B protein
Cyclophosphamide results in decreased expression of IL1B protein
IL1B protein results in increased susceptibility to Cyclophosphamide
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1B protein; [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL1B protein; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
CTD PMID:8634684 PMID:11948286 PMID:15331540 PMID:18206168 PMID:18483878 PMID:18710439 PMID:18848347 PMID:20126887 PMID:23695977 PMID:25451569 PMID:29228376 PMID:29753871 PMID:30506662 PMID:31651976 PMID:32151603 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist increases expression ISO Cyclophosphamide results in increased expression of IL1RN mRNA CTD PMID:15331540 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL2 interleukin 2 increases expression
decreases expression
decreases secretion
multiple interactions
ISO Cyclophosphamide results in increased expression of IL2 mRNA
Cyclophosphamide results in decreased expression of IL2 mRNA
Cyclophosphamide results in decreased secretion of IL2 protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]
Cyclophosphamide results in decreased expression of IL2 protein
CTD PMID:11006010 PMID:11948286 PMID:18848347 PMID:23395935 PMID:32151603 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL21 interleukin 21 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of IL21 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein]
CTD PMID:32151603 NCBI chr 4:122,610,108...122,621,066
Ensembl chr 4:122,610,108...122,621,066
JBrowse link
G IL23A interleukin 23 subunit alpha decreases secretion
decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased secretion of IL23A protein
Cyclophosphamide results in decreased expression of IL23A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL23A protein]
CTD PMID:23395935 PMID:32151603 NCBI chr12:56,334,159...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL3 interleukin 3 multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL3 protein CTD PMID:31651976 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
G IL32 interleukin 32 decreases expression EXP Cyclophosphamide results in decreased expression of NK4 mRNA CTD PMID:17403535 NCBI chr16:3,065,403...3,069,530
Ensembl chr16:3,065,297...3,082,192
JBrowse link
G IL4 interleukin 4 decreases expression
multiple interactions
increases expression
ISO Cyclophosphamide results in decreased expression of IL4 mRNA; Cyclophosphamide results in decreased expression of IL4 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]
Cyclophosphamide results in increased expression of IL4 mRNA; Cyclophosphamide results in increased expression of IL4 protein
CTD PMID:11006010 PMID:11014644 PMID:11948286 PMID:18848347 PMID:22842586 PMID:32151603 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL5 interleukin 5 increases expression ISO Cyclophosphamide results in increased expression of IL5 mRNA; Cyclophosphamide results in increased expression of IL5 protein CTD PMID:11006010 PMID:18848347 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IL6 interleukin 6 multiple interactions
increases expression
decreases secretion
ISO [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL6 protein; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL6 protein]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 mRNA]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 protein]
Cyclophosphamide results in increased expression of IL6 mRNA; Cyclophosphamide results in increased expression of IL6 protein
Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]
CTD PMID:10052129 PMID:11948286 PMID:17010015 PMID:18848347 PMID:20126887 PMID:21068404 PMID:22842586 PMID:23395935 PMID:23695977 PMID:25753322 PMID:29228376 PMID:30506662 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ILF3 interleukin enhancer binding factor 3 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ILF3 mRNA CTD PMID:16322899 NCBI chr19:10,654,295...10,692,400
Ensembl chr19:10,654,261...10,692,417
JBrowse link
G IRAG2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression ISO Cyclophosphamide results in decreased expression of LRMP mRNA CTD PMID:21041162 NCBI chr12:25,052,228...25,108,335
Ensembl chr12:25,004,342...25,108,334
JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of IRS1 mRNA CTD PMID:16322899 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,317...226,799,759
Ensembl chr 2:226,731,317...226,799,759
JBrowse link
G ISG15 ISG15 ubiquitin like modifier increases expression EXP Cyclophosphamide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540
JBrowse link
G ISL2 ISL LIM homeobox 2 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of ISL2 mRNA CTD PMID:24356939 NCBI chr15:76,336,773...76,342,475
Ensembl chr15:76,336,773...76,342,475
JBrowse link
G ITK IL2 inducible T cell kinase decreases expression ISO Cyclophosphamide results in decreased expression of ITK mRNA CTD PMID:21041162 NCBI chr 5:157,180,840...157,255,185
Ensembl chr 5:157,142,933...157,255,191
Ensembl chr 5:157,142,933...157,255,191
JBrowse link
G JCHAIN joining chain of multimeric IgA and IgM decreases expression ISO Cyclophosphamide results in decreased expression of JCHAIN mRNA CTD PMID:15331540 NCBI chr 4:70,655,541...70,666,508
Ensembl chr 4:70,655,541...70,681,817
JBrowse link
G KBTBD11 kelch repeat and BTB domain containing 11 decreases expression EXP Cyclophosphamide results in decreased expression of KBTBD11 mRNA CTD PMID:17403535 NCBI chr 8:1,970,718...2,006,943
Ensembl chr 8:1,973,677...2,006,936
JBrowse link
G KCNQ4 potassium voltage-gated channel subfamily Q member 4 decreases expression EXP Cyclophosphamide results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 1:40,783,787...40,840,457
Ensembl chr 1:40,783,787...40,840,452
JBrowse link
G KDM1A lysine demethylase 1A multiple interactions
increases expression
EXP Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in increased expression of KDM1A protein
CTD PMID:22007908 NCBI chr 1:23,019,443...23,083,691
Ensembl chr 1:23,019,443...23,083,689
JBrowse link
G KDM2A lysine demethylase 2A increases expression ISO Cyclophosphamide results in increased expression of KDM2A mRNA CTD PMID:27281708 NCBI chr11:67,119,263...67,258,082
Ensembl chr11:67,119,263...67,258,082
JBrowse link
G KDM4B lysine demethylase 4B multiple interactions EXP KDM4B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:4,969,087...5,153,603
Ensembl chr19:4,969,113...5,153,598
JBrowse link
G KDR kinase insert domain receptor decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of KDR mRNA; Cyclophosphamide results in decreased expression of KDR protein
Cyclophosphamide results in increased expression of KDR mRNA
CTD PMID:18632792 PMID:19701751 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KIF21B kinesin family member 21B decreases expression EXP Cyclophosphamide metabolite results in decreased expression of KIF21B mRNA CTD PMID:24356939 NCBI chr 1:200,969,390...201,023,714
Ensembl chr 1:200,969,390...201,023,700
Ensembl chr 1:200,969,390...201,023,700
JBrowse link
G KIF3A kinesin family member 3A multiple interactions EXP KIF3A mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:132,688,808...132,737,563
Ensembl chr 5:132,692,628...132,737,638
JBrowse link
G KITLG KIT ligand affects expression
increases expression
multiple interactions
ISO Cyclophosphamide affects the expression of KITL mRNA
Cyclophosphamide results in increased expression of KITL mRNA
[Cyclophosphamide co-treated with Sizofiran] results in increased expression of KITL mRNA
CTD PMID:10052129 PMID:12624490 PMID:12662436 NCBI chr12:88,492,793...88,580,471
Ensembl chr12:88,492,793...88,580,851
JBrowse link
G KLF13 Kruppel like factor 13 decreases expression ISO Cyclophosphamide results in decreased expression of KLF13 mRNA CTD PMID:21041162 NCBI chr15:31,326,835...31,435,665
Ensembl chr15:31,326,835...31,435,665
JBrowse link
G KLF2 Kruppel like factor 2 increases expression ISO Cyclophosphamide results in increased expression of KLF2 mRNA CTD PMID:21041162 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,817...16,327,874
Ensembl chr19:16,324,817...16,327,874
JBrowse link
G KLF4 Kruppel like factor 4 decreases response to substance EXP KLF4 results in decreased susceptibility to Cyclophosphamide CTD PMID:21833590 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G KLF5 Kruppel like factor 5 affects response to substance EXP KLF5 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541
JBrowse link
G KLRF2 killer cell lectin like receptor F2 multiple interactions ISO [Cyclophosphamide co-treated with Sizofiran] results in increased expression of KLRB1C mRNA CTD PMID:10052129 NCBI chr12:9,881,489...9,895,833
Ensembl chr12:9,881,489...9,895,833
JBrowse link
G KRCC1 lysine rich coiled-coil 1 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of KRCC1 mRNA CTD PMID:24356939 NCBI chr 2:88,027,205...88,055,783
Ensembl chr 2:88,027,205...88,064,252
JBrowse link
G KRT8 keratin 8 decreases expression ISO Cyclophosphamide results in decreased expression of KRT8 mRNA CTD PMID:21621594 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G KRT80 keratin 80 increases expression EXP Cyclophosphamide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr12:52,168,996...52,192,014
Ensembl chr12:52,168,996...52,192,014
JBrowse link
G KRTAP21-3 keratin associated protein 21-3 increases expression ISO Cyclophosphamide results in increased expression of LY6C1 mRNA CTD PMID:21041162 NCBI chr21:30,718,525...30,718,777
Ensembl chr21:30,718,525...30,718,777
JBrowse link
G LAMA5 laminin subunit alpha 5 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of LAMA5 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of LAMA5 mRNA]
CTD PMID:30760223 NCBI chr20:62,309,060...62,367,318
Ensembl chr20:62,307,955...62,367,312
JBrowse link
G LAMC2 laminin subunit gamma 2 increases expression EXP Cyclophosphamide results in increased expression of LAMC2 mRNA CTD PMID:21527772 NCBI chr 1:183,186,264...183,245,127
Ensembl chr 1:183,186,238...183,245,127
JBrowse link
G LASP1 LIM and SH3 protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of LASP1 mRNA CTD PMID:27281708 NCBI chr17:38,870,058...38,921,770
Ensembl chr17:38,869,859...38,921,770
JBrowse link
G LAT linker for activation of T cells decreases expression ISO Cyclophosphamide results in decreased expression of LAT mRNA CTD PMID:21041162 NCBI chr16:28,984,803...28,990,784
Ensembl chr16:28,984,826...28,990,783
Ensembl chr16:28,984,826...28,990,783
JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO Cyclophosphamide results in decreased expression of LCK mRNA CTD PMID:21041162 NCBI chr 1:32,251,265...32,286,165
Ensembl chr 1:32,251,239...32,286,165
JBrowse link
G LCN2 lipocalin 2 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of LCN2 mRNA
[Cyclophosphamide co-treated with Mecamylamine] results in increased expression of LCN2 mRNA
CTD PMID:15331540 PMID:18433785 PMID:20623750 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453
JBrowse link
G LDHB lactate dehydrogenase B affects response to substance EXP LDHB protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr12:21,635,342...21,657,971
Ensembl chr12:21,635,342...21,757,857
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of LEF1 mRNA CTD PMID:21041162 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
JBrowse link
G LGALS1 galectin 1 increases expression EXP Cyclophosphamide results in increased expression of LGALS1 mRNA CTD PMID:17403535 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
JBrowse link
G LGALS7 galectin 7 increases expression EXP Cyclophosphamide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr19:38,770,968...38,773,517
Ensembl chr19:38,770,971...38,773,492
Ensembl chr19:38,770,971...38,773,492
JBrowse link
G LHB luteinizing hormone subunit beta decreases secretion
multiple interactions
ISO Cyclophosphamide results in decreased secretion of LHB protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]
CTD PMID:25446862 PMID:32197949 NCBI chr19:49,015,980...49,017,091
Ensembl chr19:49,015,980...49,017,090
Ensembl chr19:49,015,980...49,017,090
JBrowse link
G LHX2 LIM homeobox 2 decreases expression ISO Cyclophosphamide results in decreased expression of LHX2 mRNA CTD PMID:27281708 NCBI chr 9:124,011,759...124,033,301
Ensembl chr 9:124,001,670...124,033,301
JBrowse link
G LIMD1 LIM domain containing 1 increases expression ISO Cyclophosphamide results in increased expression of LIMD1 mRNA CTD PMID:27281708 NCBI chr 3:45,594,105...45,686,341
Ensembl chr 3:45,555,394...45,686,341
JBrowse link
G LMCD1 LIM and cysteine rich domains 1 increases expression ISO Cyclophosphamide results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 3:8,501,823...8,574,668
Ensembl chr 3:8,501,807...8,574,668
JBrowse link
G LMNB1 lamin B1 multiple interactions EXP [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of LMNB1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of LMNB1 protein CTD PMID:15582267 NCBI chr 5:126,776,623...126,837,020
Ensembl chr 5:126,776,623...126,837,020
JBrowse link
G LONRF2 LON peptidase N-terminal domain and ring finger 2 increases expression ISO Cyclophosphamide results in increased expression of LONRF2 mRNA CTD PMID:27281708 NCBI chr 2:100,271,875...100,322,501
Ensembl chr 2:100,271,875...100,322,501
Ensembl chr 2:100,271,875...100,322,501
JBrowse link
G LSG1 large 60S subunit nuclear export GTPase 1 decreases expression EXP Cyclophosphamide results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr 3:194,640,788...194,672,191
Ensembl chr 3:194,640,791...194,672,463
JBrowse link
G LTBR lymphotoxin beta receptor increases expression ISO Cyclophosphamide results in increased expression of LTBR mRNA CTD PMID:21041162 NCBI chr12:6,375,160...6,391,571
Ensembl chr12:6,375,045...6,391,571
JBrowse link
G LTF lactotransferrin decreases expression ISO Cyclophosphamide results in decreased expression of LTF mRNA CTD PMID:21621594 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234
JBrowse link
G MAGED1 MAGE family member D1 affects response to substance EXP MAGED1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr  X:51,802,998...51,902,354
Ensembl chr  X:51,803,007...51,902,357
Ensembl chr  X:51,803,007...51,902,357
JBrowse link
G MAGED4B MAGE family member D4B affects response to substance EXP MAGED4B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr  X:52,061,827...52,069,272
Ensembl chr  X:52,061,827...52,069,248
JBrowse link
G MAN2B2 mannosidase alpha class 2B member 2 decreases expression ISO Cyclophosphamide results in decreased expression of MAN2B2 mRNA CTD PMID:27281708 NCBI chr 4:6,575,189...6,623,362
Ensembl chr 4:6,575,189...6,623,362
JBrowse link
G MAOA monoamine oxidase A increases expression EXP Cyclophosphamide results in increased expression of MAOA mRNA CTD PMID:17403535 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,824
JBrowse link
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 affects expression ISO Cyclophosphamide affects the expression of MAP3K12 mRNA CTD PMID:18246545 NCBI chr12:53,479,669...53,501,205
Ensembl chr12:53,479,669...53,500,063
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
increases expression
ISO Cyclophosphamide results in increased phosphorylation of MAPK1 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Cyclophosphamide results in increased expression of MAPK1 mRNA; Cyclophosphamide results in increased expression of MAPK1 protein modified form
CTD PMID:11599041 PMID:15733095 PMID:17110531 PMID:17409261 PMID:19638304 PMID:19696094 PMID:19996110 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions
decreases expression
affects expression
EXP
ISO
[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA
Cyclophosphamide results in decreased expression of MAPK14 mRNA
Cyclophosphamide affects the expression of MAPK14 mRNA
CTD PMID:16322899 PMID:18246545 NCBI chr 6:36,027,711...36,122,964
Ensembl chr 6:36,027,677...36,111,236
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases expression
multiple interactions
increases phosphorylation
ISO Cyclophosphamide results in increased expression of MAPK3 protein modified form
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Cyclophosphamide results in increased phosphorylation of MAPK3 protein
CTD PMID:15733095 PMID:17110531 PMID:17409261 PMID:19638304 PMID:19696094 PMID:19996110 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK7 protein CTD PMID:17110531 NCBI chr17:19,377,721...19,383,544
Ensembl chr17:19,377,721...19,383,544
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO Cyclophosphamide results in increased phosphorylation of MAPK8 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]; Mesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
CTD PMID:19696094 PMID:19996110 NCBI chr10:48,306,673...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:19996110 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MAPT microtubule associated protein tau multiple interactions EXP MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 decreases expression ISO Cyclophosphamide results in decreased expression of MARCHF7 mRNA CTD PMID:27281708 NCBI chr 2:159,712,494...159,771,027
Ensembl chr 2:159,712,457...159,771,027
JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate increases expression EXP Cyclophosphamide results in increased expression of MARCKS mRNA CTD PMID:17403535 NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475
JBrowse link
G MCM5 minichromosome maintenance complex component 5 decreases expression ISO Cyclophosphamide results in decreased expression of MCM5 mRNA CTD PMID:21041162 NCBI chr22:35,400,133...35,454,942
Ensembl chr22:35,400,134...35,425,431
JBrowse link
G MDFIC MyoD family inhibitor domain containing decreases expression EXP Cyclophosphamide results in decreased expression of MDFIC mRNA CTD PMID:17403535 NCBI chr 7:114,922,154...115,019,917
Ensembl chr 7:114,922,359...115,019,202
Ensembl chr 7:114,922,359...115,019,202
JBrowse link
G MED13L mediator complex subunit 13L multiple interactions EXP MED13L mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:115,958,576...116,277,693
Ensembl chr12:115,957,905...116,277,693
Ensembl chr12:115,957,905...116,277,693
JBrowse link
G MELK maternal embryonic leucine zipper kinase multiple interactions EXP MELK mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:36,572,870...36,677,682
Ensembl chr 9:36,572,862...36,677,683
JBrowse link
G METRN meteorin, glial cell differentiation regulator multiple interactions EXP METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr16:715,118...719,655
Ensembl chr16:715,118...719,655
JBrowse link
G MFGE8 milk fat globule EGF and factor V/VIII domain containing decreases expression ISO Cyclophosphamide results in decreased expression of MFGE8 mRNA CTD PMID:15331540 NCBI chr15:88,898,683...88,913,405
Ensembl chr15:88,898,683...88,913,381
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase decreases expression
decreases response to substance
EXP Cyclophosphamide results in decreased expression of MGMT mRNA
MGMT protein results in decreased susceptibility to Cyclophosphamide
CTD PMID:15741301 PMID:17403535 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 decreases expression ISO Cyclophosphamide results in decreased expression of MGST1 mRNA CTD PMID:11906922 NCBI chr12:16,347,115...16,377,192
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MIF macrophage migration inhibitory factor multiple interactions ISO Cyclophosphamide affects the localization of and affects the expression of MIF protein; Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein] CTD PMID:19066630 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MLH1 mutL homolog 1 decreases expression ISO Cyclophosphamide results in decreased expression of MLH1 mRNA CTD PMID:11906922 NCBI chr 3:36,993,487...37,050,846
Ensembl chr 3:36,993,350...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 increases expression ISO Cyclophosphamide results in increased expression of MMEL1 mRNA CTD PMID:27281708 NCBI chr 1:2,590,639...2,633,042
Ensembl chr 1:2,590,639...2,633,016
JBrowse link
G MMP11 matrix metallopeptidase 11 decreases expression ISO Cyclophosphamide results in decreased expression of MMP11 mRNA CTD PMID:27281708 NCBI chr22:23,772,849...23,784,316
Ensembl chr22:23,768,226...23,784,316
JBrowse link
G MMP3 matrix metallopeptidase 3 increases expression ISO Cyclophosphamide results in increased expression of MMP3 mRNA CTD PMID:15331540 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP8 matrix metallopeptidase 8 increases expression ISO Cyclophosphamide results in increased expression of MMP8 mRNA CTD PMID:27281708 NCBI chr11:102,711,796...102,724,967
Ensembl chr11:102,711,796...102,727,050
JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 affects response to substance EXP MPC2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:167,916,675...167,937,072
Ensembl chr 1:167,916,675...167,937,072
JBrowse link
G MPG N-methylpurine DNA glycosylase affects expression ISO Cyclophosphamide affects the expression of MPG mRNA CTD PMID:11906922 NCBI chr16:77,007...85,846
Ensembl chr16:77,007...85,853
Ensembl chr16:77,007...85,853
JBrowse link
G MPO myeloperoxidase multiple interactions
increases activity
ISO Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Hemin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:10749792 PMID:17979934 PMID:18710439 PMID:25451569 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MR1 major histocompatibility complex, class I-related increases expression EXP Cyclophosphamide results in increased expression of MR1 mRNA CTD PMID:21527772 NCBI chr 1:181,033,387...181,061,938
Ensembl chr 1:181,033,425...181,061,938
JBrowse link
G MS4A3 membrane spanning 4-domains A3 decreases expression EXP Cyclophosphamide results in decreased expression of MS4A3 mRNA CTD PMID:17403535 NCBI chr11:60,056,665...60,071,116
Ensembl chr11:60,056,587...60,071,115
JBrowse link
G MSH2 mutS homolog 2 decreases expression ISO Cyclophosphamide results in decreased expression of MSH2 mRNA CTD PMID:11056294 PMID:11906922 NCBI chr 2:47,403,067...47,634,501
Ensembl chr 2:47,403,067...47,663,146
Ensembl chr 2:47,403,067...47,663,146
JBrowse link
G MSH3 mutS homolog 3 decreases expression ISO Cyclophosphamide results in decreased expression of MSH3 mRNA CTD PMID:11906922 NCBI chr 5:80,654,652...80,876,815
Ensembl chr 5:80,654,652...80,876,815
JBrowse link
G MSS51 MSS51 mitochondrial translational activator increases expression ISO Cyclophosphamide results in increased expression of MSS51 mRNA CTD PMID:27281708 NCBI chr10:73,423,579...73,433,561
Ensembl chr10:73,423,579...73,433,561
JBrowse link
G MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression EXP Cyclophosphamide metabolite results in decreased expression of MTHFD2 mRNA CTD PMID:24356939 NCBI chr 2:74,198,591...74,217,565
Ensembl chr 2:74,198,610...74,217,565
Ensembl chr 2:74,198,610...74,217,565
JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase decreases expression ISO Cyclophosphamide results in decreased expression of MTR mRNA CTD PMID:27281708 NCBI chr 1:236,794,304...236,903,981
Ensembl chr 1:236,795,292...236,921,278
Ensembl chr 1:236,795,292...236,921,278
JBrowse link
G MUC13 mucin 13, cell surface associated increases expression ISO Cyclophosphamide results in increased expression of MUC13 mRNA CTD PMID:15331540 NCBI chr 3:124,905,442...124,934,751
Ensembl chr 3:124,905,442...124,953,819
JBrowse link
G MX2 MX dynamin like GTPase 2 decreases expression EXP Cyclophosphamide results in decreased expression of MX2 mRNA CTD PMID:17403535 NCBI chr21:41,361,944...41,409,393
Ensembl chr21:41,361,999...41,409,393
JBrowse link
G MXI1 MAX interactor 1, dimerization protein affects response to substance EXP MXI1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr10:110,207,605...110,287,365
Ensembl chr10:110,207,605...110,287,365
JBrowse link
G MYH10 myosin heavy chain 10 affects response to substance EXP MYH10 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr17:8,474,212...8,631,369
Ensembl chr17:8,474,205...8,630,761
Ensembl chr17:8,474,205...8,630,761
JBrowse link
G NAIP NLR family apoptosis inhibitory protein multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of NAIP mRNA CTD PMID:16322899 NCBI chr 5:70,968,166...71,025,339
Ensembl chr 5:70,968,483...71,025,114
Ensembl chr 5:70,968,483...71,025,114
JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase increases expression ISO Cyclophosphamide results in increased expression of NAMPT mRNA CTD PMID:21041162 NCBI chr 7:106,248,298...106,284,983
Ensembl chr 7:106,248,298...106,286,326
Ensembl chr 7:106,248,298...106,286,326
JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 increases expression EXP Cyclophosphamide metabolite results in increased expression of NANOS1 mRNA CTD PMID:24356939 NCBI chr10:119,029,714...119,033,730
Ensembl chr10:119,029,714...119,033,730
JBrowse link
G NASP nuclear autoantigenic sperm protein increases expression ISO Cyclophosphamide results in increased expression of NASP mRNA CTD PMID:16141653 NCBI chr 1:45,584,041...45,618,893
Ensembl chr 1:45,583,846...45,618,904
JBrowse link
G NCOA7 nuclear receptor coactivator 7 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of NCOA7 mRNA CTD PMID:24356939 NCBI chr 6:125,780,943...125,932,034
Ensembl chr 6:125,781,161...125,932,034
JBrowse link
G NDUFS2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Cyclophosphamide results in decreased expression of NDUFS2 mRNA CTD PMID:15331540 NCBI chr 1:161,197,417...161,214,395
Ensembl chr 1:161,197,104...161,214,395
Ensembl chr 1:161,197,104...161,214,395
JBrowse link
G NETO2 neuropilin and tolloid like 2 increases expression EXP Cyclophosphamide results in increased expression of NETO2 mRNA CTD PMID:21527772 NCBI chr16:47,077,703...47,144,025
Ensembl chr16:47,077,703...47,143,945
JBrowse link
G NFATC3 nuclear factor of activated T cells 3 decreases expression ISO Cyclophosphamide results in decreased expression of NFATC3 mRNA CTD PMID:21041162 NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 multiple interactions
increases response to substance
increases expression
decreases expression
ISO [astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 protein]
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
NFE2L2 gene mutant form results in increased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of NFE2L2 protein
CTD PMID:20038455 PMID:20433640 PMID:27633142 NCBI chr 2:177,230,303...177,265,131
Ensembl chr 2:177,227,595...177,392,697
JBrowse link
G NFE2L3 nuclear factor, erythroid 2 like 3 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of NFE2L3 mRNA CTD PMID:24356939 NCBI chr 7:26,152,198...26,187,137
Ensembl chr 7:26,152,198...26,187,137
JBrowse link
G NFKBIA NFKB inhibitor alpha increases phosphorylation
multiple interactions
ISO Cyclophosphamide results in increased phosphorylation of NFKBIA protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of NFKBIA protein]
CTD PMID:30506662 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G NFKBIZ NFKB inhibitor zeta increases expression ISO Cyclophosphamide results in increased expression of NFKBIZ mRNA CTD PMID:15331540 NCBI chr 3:101,827,990...101,861,022
Ensembl chr 3:101,827,991...101,861,022
JBrowse link
G NGF nerve growth factor multiple interactions
increases expression
decreases expression
ISO 3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]; VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]
NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]
Cyclophosphamide results in increased expression of NGF mRNA; Cyclophosphamide results in increased expression of NGF protein
Cyclophosphamide results in decreased expression of NGF protein
CTD PMID:10683293 PMID:16879691 PMID:18299998 PMID:18632792 PMID:19996110 PMID:20127836 NCBI chr 1:115,285,915...115,338,253
Ensembl chr 1:115,285,917...115,338,256
Ensembl chr 1:115,285,917...115,338,256
Ensembl chr 1:115,285,917...115,338,256
Ensembl chr 1:115,285,917...115,338,256
JBrowse link
G NGFR nerve growth factor receptor increases expression ISO Cyclophosphamide results in increased expression of NGFR mRNA; Cyclophosphamide results in increased expression of NGFR protein CTD PMID:8817519 PMID:18189308 PMID:18842820 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008
JBrowse link
G NID1 nidogen 1 affects response to substance EXP NID1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:235,975,830...236,065,092
Ensembl chr 1:235,975,830...236,065,109
JBrowse link
G NKAIN1 sodium/potassium transporting ATPase interacting 1 multiple interactions EXP NKAIN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:31,179,270...31,239,887
Ensembl chr 1:31,179,745...31,239,887
JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO Cyclophosphamide results in increased expression of NME1 mRNA CTD PMID:11599041 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428
Ensembl chr17:51,153,559...51,162,428
JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions
increases activity
ISO Cyclophosphamide results in increased expression of NOS2 mRNA; Cyclophosphamide results in increased expression of NOS2 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Cyclophosphamide results in increased activity of NOS2 protein
Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; ginkgolide B inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; pimagedine inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
CTD PMID:9006340 PMID:10607705 PMID:11046124 PMID:15821589 PMID:16879691 PMID:18206168 PMID:18296739 PMID:18710439 PMID:19691848 PMID:21068404 PMID:25753322 PMID:29753871 PMID:32197949 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 decreases activity
increases expression
ISO Cyclophosphamide results in decreased activity of NOS3 protein
Cyclophosphamide results in increased expression of NOS3 protein
CTD PMID:9006340 PMID:16125470 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NPPB natriuretic peptide B increases expression EXP Cyclophosphamide results in increased expression of NPPB protein CTD PMID:17562616 PMID:18548196 PMID:18999883 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
JBrowse link
G NPRL2 NPR2 like, GATOR1 complex subunit decreases expression EXP Cyclophosphamide results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 3:50,347,330...50,350,821
Ensembl chr 3:50,347,330...50,350,826
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
increases expression
ISO Cyclophosphamide results in decreased expression of NQO1 mRNA; Cyclophosphamide results in decreased expression of NQO1 protein
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
Cyclophosphamide results in increased expression of NQO1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
CTD PMID:11906922 PMID:20038455 PMID:20433640 PMID:21041162 PMID:27633142 PMID:32197949 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 decreases expression ISO Cyclophosphamide results in decreased expression of NR1H4 mRNA CTD PMID:28391356 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases activity
multiple interactions
EXP Cyclophosphamide results in increased activity of NR1I2 protein
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Cyclophosphamide binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]
CTD PMID:17041008 PMID:18839173 PMID:20041327 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,485
Ensembl chr 3:119,780,484...119,818,485
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions EXP [Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:161,229,666...161,238,623
Ensembl chr 1:161,229,666...161,238,302
Ensembl chr 1:161,229,666...161,238,302
JBrowse link
G NR2C2 nuclear receptor subfamily 2 group C member 2 increases expression ISO Cyclophosphamide results in increased expression of NR2C2 mRNA CTD PMID:27281708 NCBI chr 3:14,947,583...15,049,273
Ensembl chr 3:14,947,584...15,053,600
JBrowse link
G NRAP nebulin related anchoring protein increases expression ISO Cyclophosphamide results in increased expression of NRAP mRNA CTD PMID:27281708 NCBI chr10:113,588,714...113,664,046
Ensembl chr10:113,588,716...113,664,127
Ensembl chr10:113,588,716...113,664,127
JBrowse link
G NRDC nardilysin convertase decreases expression ISO Cyclophosphamide results in decreased expression of NRD1 mRNA CTD PMID:27281708 NCBI chr 1:51,789,210...51,878,727
Ensembl chr 1:51,789,191...51,878,937
JBrowse link
G NRG1 neuregulin 1 increases expression EXP Cyclophosphamide results in increased expression of NRG1 mRNA CTD PMID:21527772 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G NRP1 neuropilin 1 decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of NRP1 mRNA
Cyclophosphamide results in increased expression of NRP1 mRNA
CTD PMID:15331540 PMID:18632792 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262
JBrowse link
G NRP2 neuropilin 2 increases expression ISO Cyclophosphamide results in increased expression of NRP2 mRNA CTD PMID:18632792 NCBI chr 2:205,682,501...205,798,131
Ensembl chr 2:205,681,990...205,798,133
JBrowse link
G NT5C2 5'-nucleotidase, cytosolic II increases expression EXP Cyclophosphamide results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr10:103,088,017...103,193,301
Ensembl chr10:103,087,185...103,277,605
Ensembl chr10:103,087,185...103,277,605
JBrowse link
G NTF3 neurotrophin 3 increases expression ISO Cyclophosphamide results in increased expression of NTF3 mRNA CTD PMID:10683293 NCBI chr12:5,432,108...5,495,299
Ensembl chr12:5,432,108...5,521,536
JBrowse link
G NTF4 neurotrophin 4 increases expression ISO Cyclophosphamide results in increased expression of NTF4 mRNA CTD PMID:10683293 NCBI chr19:49,058,284...49,065,076
Ensembl chr19:49,061,066...49,065,054
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK1 protein CTD PMID:12412144 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,640...156,881,850
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK2 protein CTD PMID:12412144 NCBI chr 9:84,668,458...85,027,070
Ensembl chr 9:84,668,551...85,027,070
Ensembl chr 9:84,668,551...85,027,070
JBrowse link
G NUP42 nucleoporin 42 increases expression ISO Cyclophosphamide results in increased expression of NUPL2 mRNA CTD PMID:27281708 NCBI chr 7:23,181,298...23,201,011
Ensembl chr 7:23,181,841...23,201,011
JBrowse link
G OCLN occludin multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of OCLN protein] CTD PMID:32151603 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G ODC1 ornithine decarboxylase 1 increases expression ISO Cyclophosphamide results in increased expression of ODC1 mRNA CTD PMID:11599041 NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase decreases expression ISO Cyclophosphamide results in decreased expression of OGG1 protein CTD PMID:27032448 NCBI chr 3:9,749,952...9,788,246
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G OPN3 opsin 3 affects response to substance EXP OPN3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:241,593,124...241,640,369
Ensembl chr 1:241,590,102...241,677,376
Ensembl chr 1:241,590,102...241,677,376
JBrowse link
G OSM oncostatin M affects expression ISO Cyclophosphamide affects the expression of OSM mRNA CTD PMID:12624490 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851
JBrowse link
G P2RX3 purinergic receptor P2X 3 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of P2RX3 protein
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]
CTD PMID:23666265 NCBI chr11:57,335,943...57,372,399
Ensembl chr11:57,338,352...57,372,396
JBrowse link
G P2RY2 purinergic receptor P2Y2 decreases expression EXP Cyclophosphamide results in decreased expression of P2RY2 mRNA CTD PMID:17403535 NCBI chr11:73,200,416...73,246,743
Ensembl chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427
JBrowse link
G PAIP1 poly(A) binding protein interacting protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758
JBrowse link
G PALM2AKAP2 PALM2 and AKAP2 fusion increases expression EXP Cyclophosphamide results in increased expression of PALM2AKAP2 mRNA CTD PMID:17403535 NCBI chr 9:109,640,787...110,172,512
Ensembl chr 9:109,498,325...110,172,512
Ensembl chr 9:109,498,325...110,172,512
JBrowse link
G PARD3 par-3 family cell polarity regulator decreases expression EXP Cyclophosphamide results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases expression
increases cleavage
decreases expression
EXP
ISO
[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein
Cyclophosphamide results in increased expression of PARP1 mRNA
Cyclophosphamide results in increased cleavage of PARP1 protein
Cyclophosphamide results in decreased expression of PARP1 mRNA
CTD PMID:11599041 PMID:11723234 PMID:11906922 PMID:15582267 PMID:17898787 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,691...226,408,093
JBrowse link
G PCNA proliferating cell nuclear antigen affects expression
multiple interactions
decreases expression
increases expression
ISO Cyclophosphamide affects the expression of PCNA mRNA
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of PCNA mRNA]
Cyclophosphamide results in decreased expression of PCNA protein
Cyclophosphamide results in increased expression of PCNA mRNA
CTD PMID:11056294 PMID:18246545 PMID:19701751 PMID:21041162 PMID:31557371 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 decreases expression ISO Cyclophosphamide results in decreased expression of PCSK2 mRNA CTD PMID:15331540 NCBI chr20:17,226,107...17,484,578
Ensembl chr20:17,226,107...17,484,578
JBrowse link
G PDCD4 programmed cell death 4 decreases expression EXP Cyclophosphamide results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 decreases expression ISO Cyclophosphamide results in decreased expression of PDIA3 mRNA CTD PMID:11906922 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,410...43,773,278
JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 increases expression ISO Cyclophosphamide results in increased expression of PDIA4 mRNA CTD PMID:11599041 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662
JBrowse link
G PELI1 pellino E3 ubiquitin protein ligase 1 decreases expression EXP Cyclophosphamide metabolite results in decreased expression of PELI1 mRNA CTD PMID:24356939 NCBI chr 2:64,092,652...64,144,421
Ensembl chr 2:64,092,652...64,144,420
JBrowse link
G PER1 period circadian regulator 1 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of PER1 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of PER1 mRNA]
CTD PMID:30760223 NCBI chr17:8,140,470...8,156,360
Ensembl chr17:8,140,472...8,156,506
JBrowse link
G PHLDA2 pleckstrin homology like domain family A member 2 increases expression EXP Cyclophosphamide results in increased expression of PHLDA2 mRNA CTD PMID:17403535 NCBI chr11:2,928,273...2,929,420
Ensembl chr11:2,928,273...2,929,420
JBrowse link
G PIGA phosphatidylinositol glycan anchor biosynthesis class A increases mutagenesis ISO Cyclophosphamide results in increased mutagenesis of PIGA CTD PMID:22923490 NCBI chr  X:15,319,451...15,335,554
Ensembl chr  X:15,319,452...15,335,554
Ensembl chr  X:15,319,452...15,335,554
JBrowse link
G PIGR polymeric immunoglobulin receptor increases expression ISO Cyclophosphamide results in increased expression of PIGR mRNA CTD PMID:15331540 NCBI chr 1:206,928,522...206,946,466
Ensembl chr 1:206,928,522...206,946,466
JBrowse link
G PLA2G4A phospholipase A2 group IVA increases expression ISO Cyclophosphamide results in increased expression of PLA2G4A mRNA CTD PMID:21041162 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981
JBrowse link
G PLAU plasminogen activator, urokinase increases expression EXP Cyclophosphamide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr10:73,909,182...73,917,497
Ensembl chr10:73,909,177...73,917,496
JBrowse link
G PLOD1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD1 mRNA CTD PMID:16322899 NCBI chr 1:11,934,717...11,975,537
Ensembl chr 1:11,934,205...11,975,538
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 multiple interactions EXP [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD3 mRNA CTD PMID:16322899 NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
JBrowse link
G PMS1 PMS1 homolog 1, mismatch repair system component increases expression ISO Cyclophosphamide results in increased expression of PMS1 mRNA CTD PMID:11056294 NCBI chr 2:189,784,142...189,877,629
Ensembl chr 2:189,784,085...189,877,629
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component decreases expression ISO Cyclophosphamide results in decreased expression of PMS2 mRNA CTD PMID:11056294 NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,106
JBrowse link
G POLM DNA polymerase mu increases expression EXP Cyclophosphamide results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr 7:44,072,062...44,082,530
Ensembl chr 7:44,072,062...44,082,530
JBrowse link
G POMC proopiomelanocortin increases expression ISO Cyclophosphamide results in increased expression of POMC protein CTD PMID:15276878 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G PON1 paraoxonase 1 increases activity ISO Cyclophosphamide results in increased activity of PON1 protein CTD PMID:17874068 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G POR cytochrome p450 oxidoreductase multiple interactions
increases expression
EXP
ISO
POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
Cyclophosphamide results in increased expression of POR mRNA
CTD PMID:9766669 PMID:10919648 PMID:11599041 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
JBrowse link
G POSTN periostin decreases expression ISO Cyclophosphamide results in decreased expression of POSTN mRNA CTD PMID:15331540 NCBI chr13:37,562,585...37,598,839
Ensembl chr13:37,562,583...37,598,844
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of PPARA protein] CTD PMID:29753871 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,756
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression
increases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of PPARG mRNA
Cyclophosphamide results in increased expression of PPARG mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of PPARG mRNA]
CTD PMID:25446862 PMID:27281708 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PRDM13 PR/SET domain 13 affects expression ISO Cyclophosphamide affects the expression of PRDM13 mRNA CTD PMID:27281708 NCBI chr 6:99,606,833...99,615,562
Ensembl chr 6:99,606,730...99,615,578
Ensembl chr 6:99,606,730...99,615,578
JBrowse link
G PRKCG protein kinase C gamma decreases expression ISO Cyclophosphamide results in decreased expression of PRKCG mRNA CTD PMID:27281708 NCBI chr19:53,882,197...53,907,652
Ensembl chr19:53,879,190...53,907,652
JBrowse link
G PRLR prolactin receptor decreases expression ISO Cyclophosphamide results in decreased expression of PRLR mRNA CTD PMID:15331540 NCBI chr 5:35,048,756...35,230,724
Ensembl chr 5:35,048,756...35,230,487
JBrowse link
G PROCR protein C receptor increases expression EXP Cyclophosphamide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr20:35,172,072...35,215,989
Ensembl chr20:35,172,072...35,216,240
JBrowse link
G PRSS3 serine protease 3 affects response to substance EXP PRSS3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 9:33,750,522...33,799,231
Ensembl chr 9:33,750,466...33,799,231
Ensembl chr 9:33,750,466...33,799,231
JBrowse link
G PRTN3 proteinase 3 decreases expression EXP Cyclophosphamide results in decreased expression of PRTN3 mRNA CTD PMID:17403535 NCBI chr19:840,965...848,175
Ensembl chr19:840,999...848,175
JBrowse link
G PSMA5 proteasome 20S subunit alpha 5 increases expression EXP Cyclophosphamide results in increased expression of PSMA5 protein CTD PMID:17475930 NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448
JBrowse link
G PTCRA pre T cell antigen receptor alpha decreases expression ISO Cyclophosphamide results in decreased expression of PTCRA mRNA CTD PMID:21041162 NCBI chr 6:42,915,597...42,925,838
Ensembl chr 6:42,915,989...42,925,835
Ensembl chr 6:42,915,989...42,925,835
JBrowse link
G PTGER1 prostaglandin E receptor 1 decreases expression ISO Cyclophosphamide results in decreased expression of PTGER1 protein CTD PMID:20346049 NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
JBrowse link
G PTGER4 prostaglandin E receptor 4 multiple interactions
increases expression
ISO Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGER4 protein] CTD PMID:18514386 PMID:20346049 NCBI chr 5:40,679,915...40,740,936
Ensembl chr 5:40,679,915...40,693,735
JBrowse link
G PTGES3 prostaglandin E synthase 3 increases expression ISO Cyclophosphamide results in increased expression of PTGES3 mRNA CTD PMID:11599041 NCBI chr12:56,663,349...56,689,575
Ensembl chr12:56,663,341...56,688,408
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 increases expression ISO Cyclophosphamide results in increased expression of PTGS1 mRNA CTD PMID:21041162 NCBI chr 9:122,369,906...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 affects response to substance
multiple interactions
increases expression
EXP
ISO
PTGS2 protein affects the susceptibility to Cyclophosphamide
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
Cyclophosphamide results in increased expression of PTGS2 mRNA; Cyclophosphamide results in increased expression of PTGS2 protein
Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
CTD PMID:12388444 PMID:15331540 PMID:16217747 PMID:17537839 PMID:18514386 PMID:19303104 PMID:25753322 PMID:29753871 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G PTP4A1 protein tyrosine phosphatase 4A1 increases expression ISO Cyclophosphamide results in increased expression of PTP4A1 mRNA CTD PMID:15331540 NCBI chr 6:63,516,440...63,583,588
Ensembl chr 6:63,521,746...63,583,436
JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C decreases expression ISO Cyclophosphamide results in decreased expression of PTPRC mRNA CTD PMID:21041162 NCBI chr 1:198,639,025...198,757,476
Ensembl chr 1:198,638,457...198,757,476
JBrowse link
G PURA purine rich element binding protein A increases expression ISO Cyclophosphamide results in increased expression of PURA mRNA CTD PMID:11599041 NCBI chr 5:140,114,109...140,125,619
Ensembl chr 5:140,107,777...140,125,619
JBrowse link
G RAD50 RAD50 double strand break repair protein increases expression ISO Cyclophosphamide results in increased expression of RAD50 mRNA CTD PMID:11056294 NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349
JBrowse link
G RAD51 RAD51 recombinase decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of RAD51 mRNA
Cyclophosphamide results in increased expression of RAD51 mRNA
CTD PMID:11599041 PMID:21041162 NCBI chr15:40,694,774...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
G RAD54L RAD54 like decreases expression ISO Cyclophosphamide results in decreased expression of RAD54L mRNA CTD PMID:11056294 NCBI chr 1:46,247,688...46,278,477
Ensembl chr 1:46,246,461...46,278,480
JBrowse link
G RAG1 recombination activating 1 decreases expression ISO Cyclophosphamide results in decreased expression of RAG1 mRNA CTD PMID:21041162 NCBI chr11:36,510,353...36,579,762
Ensembl chr11:36,510,709...36,593,156
JBrowse link
G RAMP1 receptor activity modifying protein 1 increases expression
multiple interactions
EXP Cyclophosphamide results in increased expression of RAMP1 mRNA
RAMP1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
CTD PMID:16896004 PMID:17403535 NCBI chr 2:237,858,555...237,912,114
Ensembl chr 2:237,858,893...237,912,106
JBrowse link
G RAPSN receptor associated protein of the synapse increases expression ISO Cyclophosphamide results in increased expression of RAPSN mRNA CTD PMID:27281708 NCBI chr11:47,437,764...47,449,136
Ensembl chr11:47,437,764...47,449,143
JBrowse link
G RARA retinoic acid receptor alpha increases expression ISO Cyclophosphamide results in increased expression of RARA mRNA CTD PMID:16141653 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G RARG retinoic acid receptor gamma decreases expression ISO Cyclophosphamide results in decreased expression of RARG mRNA CTD PMID:27281708 NCBI chr12:53,210,569...53,232,231
Ensembl chr12:53,210,567...53,232,980
JBrowse link
G RBPMS RNA binding protein, mRNA processing factor increases expression EXP Cyclophosphamide results in increased expression of RBPMS mRNA CTD PMID:17403535 NCBI chr 8:30,384,541...30,572,261
Ensembl chr 8:30,384,511...30,572,256
JBrowse link
G RC3H1 ring finger and CCCH-type domains 1 decreases expression ISO Cyclophosphamide results in decreased expression of RC3H1 mRNA CTD PMID:27281708 NCBI chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357
Ensembl chr 1:173,931,084...174,022,357
JBrowse link
G RC3H2 ring finger and CCCH-type domains 2 decreases expression ISO Cyclophosphamide results in decreased expression of RC3H2 mRNA CTD PMID:27281708 NCBI chr 9:122,844,556...122,905,359
Ensembl chr 9:122,844,556...122,905,359
JBrowse link
G REG3A regenerating family member 3 alpha increases expression ISO Cyclophosphamide results in increased expression of REG3A mRNA; Cyclophosphamide results in increased expression of REG3B mRNA
Cyclophosphamide results in increased expression of REG3B protein
CTD PMID:15331540 PMID:18295254 NCBI chr 2:79,157,006...79,159,753