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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycolaldehyde
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Accession:CHEBI:17071 term browser browse the term
Definition:The glycolaldehyde derived from ethylene glycol. The parent of the class of glycolaldehydes.
Synonyms:related_synonym: Formula=C2H4O2;   GLYCOALDEHYDE;   Glycolic aldehyde;   Hydroxyacetaldehyde;   InChI=1S/C2H4O2/c3-1-2-4/h1,4H,2H2;   InChIKey=WGCNASOHLSPBMP-UHFFFAOYSA-N;   Methylol formaldehyde;   Monomethylolformaldehyde;   SMILES=[H]C(=O)CO;   glycollaldehyde
 alt_id: CHEBI:14347;   CHEBI:24386;   CHEBI:5474
 xref: Beilstein:506029;   CAS:141-46-8;   ECMDB:ECMDB02165;   FooDB:FDB030893;   HMDB:HMDB0003344;   KEGG:C00266;   KNApSAcK:C00007457
 xref_mesh: MESH:C010972
 xref: MetaCyc:GLYCOLALDEHYDE;   PDBeChem:DW3;   PMID:20960220;   PMID:21378371;   PMID:21472960;   PMID:21820089;   PMID:23543734;   PMID:29400466;   PMID:35348319;   PMID:35624799;   Reaxys:506029;   Wikipedia:Glycolaldehyde;   YMDB:YMDB00343
 cyclic_relationship: is_tautomer_of CHEBI:131198


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glycolaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions
increases degradation		 ISO
EXP		 glycolaldehyde inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]
glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein]
glycolaldehyde results in increased degradation of ABCA1 protein		 CTD PMID:15983222 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2, mitochondrial multiple interactions ISO [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde CTD PMID:21376711 NCBI chr 5:121,704,090...121,731,887
Ensembl chr 5:121,704,090...121,731,887 		JBrowse link
G Apoa1 apolipoprotein A-I multiple interactions EXP glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein] CTD PMID:15983222 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764 		JBrowse link
G Cat catalase decreases response to substance
decreases activity		 ISO CAT protein results in decreased susceptibility to glycolaldehyde
glycolaldehyde results in decreased activity of CAT protein		 CTD PMID:21376711 PMID:21378371 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ctss cathepsin S decreases activity ISO glycolaldehyde results in decreased activity of CTSS protein CTD PMID:16671891 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714 		JBrowse link
G Glo1 glyoxalase 1 decreases activity ISO glycolaldehyde results in decreased activity of GLO1 protein CTD PMID:21378371 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biochemical role 21431
          metabolite 21379
            fundamental metabolite 14986
              glycolaldehyde 6
                glycolaldehyde phosphate 0
                glycolaldehyde triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            heteroorganic entity 21482
                              organochalcogen compound 20966
                                organooxygen compound 20806
                                  carbon oxoacid 19593
                                    carboxylic acid 19589
                                      carboacyl group 18277
                                        univalent carboacyl group 18277
                                          formyl group 9120
                                            aldehyde 9120
                                              hydroxyaldehyde 820
                                                glycolaldehydes 6
                                                  glycolaldehyde 6
                                                    glycolaldehyde phosphate 0
                                                    glycolaldehyde triphosphate 0
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