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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycolaldehyde
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Accession:CHEBI:17071 term browser browse the term
Definition:The glycolaldehyde derived from ethylene glycol. The parent of the class of glycolaldehydes.
Synonyms:related_synonym: Formula=C2H4O2;   GLYCOALDEHYDE;   Glycolic aldehyde;   Hydroxyacetaldehyde;   InChI=1S/C2H4O2/c3-1-2-4/h1,4H,2H2;   InChIKey=WGCNASOHLSPBMP-UHFFFAOYSA-N;   Methylol formaldehyde;   Monomethylolformaldehyde;   SMILES=[H]C(=O)CO;   glycollaldehyde
 alt_id: CHEBI:14347;   CHEBI:24386;   CHEBI:5474
 xref: Beilstein:506029;   CAS:141-46-8;   ECMDB:ECMDB02165;   HMDB:HMDB0003344;   KEGG:C00266;   KNApSAcK:C00007457
 xref_mesh: MESH:C010972
 xref: MetaCyc:GLYCOLALDEHYDE;   PMID:20960220;   PMID:21378371;   PMID:21472960;   PMID:21820089;   PMID:23543734;   Reaxys:506029;   Wikipedia:Glycolaldehyde;   YMDB:YMDB00343
 cyclic_relationship: is_tautomer_of CHEBI:131198


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glycolaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases degradation
ISO glycolaldehyde inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]
glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein]
glycolaldehyde results in increased degradation of ABCA1 protein
CTD PMID:15983222 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of glycolaldehyde CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde CTD PMID:21376711 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein] CTD PMID:15983222 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Cat catalase decreases response to substance
decreases activity
EXP CAT protein results in decreased susceptibility to glycolaldehyde
glycolaldehyde results in decreased activity of CAT protein
CTD PMID:21376711 PMID:21378371 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ctss cathepsin S decreases activity ISO glycolaldehyde results in decreased activity of CTSS protein CTD PMID:16671891 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Glo1 glyoxalase 1 decreases activity EXP glycolaldehyde results in decreased activity of GLO1 protein CTD PMID:21378371 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19761
    role 19711
      biological role 19711
        biochemical role 19301
          metabolite 19282
            fundamental metabolite 12653
              glycolaldehyde 7
                glycolaldehyde phosphate 0
                glycolaldehyde triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19569
                        carbon atom 19559
                          organic molecular entity 19559
                            organic group 18593
                              organic divalent group 18584
                                organodiyl group 18584
                                  carbonyl group 18499
                                    carbonyl compound 18499
                                      carboxylic acid 18151
                                        carboacyl group 17410
                                          univalent carboacyl group 17410
                                            formyl group 8787
                                              aldehyde 8787
                                                glycolaldehydes 7
                                                  glycolaldehyde 7
                                                    glycolaldehyde phosphate 0
                                                    glycolaldehyde triphosphate 0
paths to the root