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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glycolaldehyde
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Accession:CHEBI:17071 term browser browse the term
Definition:The glycolaldehyde derived from ethylene glycol. The parent of the class of glycolaldehydes.
Synonyms:related_synonym: Formula=C2H4O2;   GLYCOALDEHYDE;   Glycolic aldehyde;   Hydroxyacetaldehyde;   InChI=1S/C2H4O2/c3-1-2-4/h1,4H,2H2;   InChIKey=WGCNASOHLSPBMP-UHFFFAOYSA-N;   Methylol formaldehyde;   Monomethylolformaldehyde;   SMILES=[H]C(=O)CO;   glycollaldehyde
 alt_id: CHEBI:14347;   CHEBI:24386;   CHEBI:5474
 xref: Beilstein:506029;   CAS:141-46-8;   ECMDB:ECMDB02165;   HMDB:HMDB0003344;   KEGG:C00266;   KNApSAcK:C00007457
 xref_mesh: MESH:C010972
 xref: MetaCyc:GLYCOLALDEHYDE;   PMID:20960220;   PMID:21378371;   PMID:21472960;   PMID:21820089;   PMID:23543734;   Reaxys:506029;   Wikipedia:Glycolaldehyde;   YMDB:YMDB00343
 cyclic_relationship: is_tautomer_of CHEBI:131198



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glycolaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases degradation
ISO glycolaldehyde inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]
glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein]
glycolaldehyde results in increased degradation of ABCA1 protein
CTD PMID:15983222 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of glycolaldehyde CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde CTD PMID:21376711 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO glycolaldehyde inhibits the reaction [ABCA1 protein binds to APOA1 protein] CTD PMID:15983222 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Cat catalase decreases response to substance
decreases activity
EXP CAT protein results in decreased susceptibility to glycolaldehyde
glycolaldehyde results in decreased activity of CAT protein
CTD PMID:21376711 PMID:21378371 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ctss cathepsin S decreases activity ISO glycolaldehyde results in decreased activity of CTSS protein CTD PMID:16671891 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Glo1 glyoxalase 1 decreases activity EXP glycolaldehyde results in decreased activity of GLO1 protein CTD PMID:21378371 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    role 20009
      biological role 20008
        biochemical role 19630
          metabolite 19611
            fundamental metabolite 12804
              glycolaldehyde 7
                glycolaldehyde phosphate 0
                glycolaldehyde triphosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic group 18943
                              organic divalent group 18928
                                organodiyl group 18928
                                  carbonyl group 18877
                                    carbonyl compound 18877
                                      carboxylic acid 18565
                                        carboacyl group 17658
                                          univalent carboacyl group 17658
                                            formyl group 8805
                                              aldehyde 8805
                                                glycolaldehydes 7
                                                  glycolaldehyde 7
                                                    glycolaldehyde phosphate 0
                                                    glycolaldehyde triphosphate 0
paths to the root