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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dinitrogen oxide
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Accession:CHEBI:17045 term browser browse the term
Definition:A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Synonyms:exact_synonym: oxidodinitrogen(N--N)
 related_synonym: Dinitrogen monoxide;   Distickstoffmonoxid;   E942;   Formula=N2O;   InChI=1S/N2O/c1-2-3;   InChIKey=GQPLMRYTRLFLPF-UHFFFAOYSA-N;   Lachgas;   N2O;   NITROUS OXIDE;   NNO;   R-744A;   SMILES=[O-][N+]#N;   Stickstoff(I)-oxid;   diazyne 1-oxide;   factitious air;   gaz hilarant;   laughing gas;   nitrogen protoxide;   nitrogenium oxydulatum;   oxyde nitreux;   protoxyde d'azote
 alt_id: CHEBI:14661;   CHEBI:25568;   CHEBI:44250;   CHEBI:7598
 xref: Beilstein:8137358;   CAS:10024-97-2;   Drug_Central:4238;   Gmelin:2153410;   KEGG:C00887;   KEGG:D00102
 xref_mesh: MESH:D009609
 xref: PDBeChem:N2O;   PMID:11159233;   PMID:11811748;   PMID:15316643;   PMID:15644008;   PMID:16179535;   PMID:17093360;   PMID:18992971;   PMID:19910265;   PMID:21622873;   PMID:23643142;   PMID:7880215;   Reaxys:8137358;   UM-BBD_compID:c0650;   Wikipedia:Nitrous_oxide


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dinitrogen oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntf ciliary neurotrophic factor multiple interactions
decreases activity
ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]; Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
Nitrous Oxide results in decreased activity of CNTF protein
Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]
CTD PMID:15748169 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [Isoflurane co-treated with Nitrous Oxide] affects the expression of GABRA4 mRNA CTD PMID:16733821 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO GRIN2A protein affects the susceptibility to [Nitrous Oxide co-treated with sevoflurane] CTD PMID:15731593 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases activity ISO Nitrous Oxide results in decreased activity of MTR protein CTD PMID:18472229 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Pla2g7 phospholipase A2 group VII affects expression ISO Nitrous Oxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Pomc proopiomelanocortin increases secretion EXP Nitrous Oxide results in increased secretion of POMC protein CTD PMID:2846107 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:15748169 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]
Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
CTD PMID:15748169 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      application 19481
        refrigerant 17694
          dinitrogen oxide 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      chalcogen 19469
                        oxygen atom 19445
                          oxygen molecular entity 19445
                            oxide 11762
                              inorganic oxide 7531
                                nitrogen oxide 404
                                  dinitrogen oxide 8
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