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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dinitrogen oxide
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Accession:CHEBI:17045 term browser browse the term
Definition:A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream.
Synonyms:exact_synonym: oxidodinitrogen(N--N)
 related_synonym: Dinitrogen monoxide;   Distickstoffmonoxid;   E942;   Formula=N2O;   InChI=1S/N2O/c1-2-3;   InChIKey=GQPLMRYTRLFLPF-UHFFFAOYSA-N;   Lachgas;   N2O;   NITROUS OXIDE;   NNO;   R-744A;   SMILES=[O-][N+]#N;   Stickstoff(I)-oxid;   diazyne 1-oxide;   factitious air;   gaz hilarant;   laughing gas;   nitrogen protoxide;   nitrogenium oxydulatum;   oxyde nitreux;   protoxyde d'azote
 alt_id: CHEBI:14661;   CHEBI:25568;   CHEBI:44250;   CHEBI:7598
 xref: Beilstein:8137358;   CAS:10024-97-2;   Drug_Central:4238;   Gmelin:2153410;   KEGG:C00887;   KEGG:D00102
 xref_mesh: MESH:D009609
 xref: PDBeChem:N2O;   PMID:11159233;   PMID:11811748;   PMID:15316643;   PMID:15644008;   PMID:16179535;   PMID:17093360;   PMID:18992971;   PMID:19910265;   PMID:21622873;   PMID:23643142;   PMID:7880215;   Reaxys:8137358;   UM-BBD_compID:c0650;   Wikipedia:Nitrous_oxide


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dinitrogen oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntf ciliary neurotrophic factor multiple interactions
decreases activity
ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]; Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
Nitrous Oxide results in decreased activity of CNTF protein
Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]
CTD PMID:15748169 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO [Isoflurane co-treated with Nitrous Oxide] affects the expression of GABRA4 mRNA CTD PMID:16733821 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO GRIN2A protein affects the susceptibility to [Nitrous Oxide co-treated with sevoflurane] CTD PMID:15731593 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases activity ISO Nitrous Oxide results in decreased activity of MTR protein CTD PMID:18472229 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Pla2g7 phospholipase A2 group VII affects expression ISO Nitrous Oxide affects the expression of PLA2G7 CTD PMID:21356620 NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
JBrowse link
G Pomc proopiomelanocortin increases secretion EXP Nitrous Oxide results in increased secretion of POMC protein CTD PMID:2846107 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:15748169 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Nitrous Oxide inhibits the reaction [CNTF protein results in increased activity of STAT3 protein]
Nitrous Oxide inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
CTD PMID:15748169 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        refrigerant 17418
          dinitrogen oxide 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            oxide 11578
                              inorganic oxide 7408
                                nitrogen oxide 400
                                  dinitrogen oxide 8
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