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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tetrachlorohydroquinone
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Accession:CHEBI:17042 term browser browse the term
Definition:A tetrachlorobenzene that is 1,2,4,5-tetrachlorobenzene in which the hydrogens at positions 3 and 6 are replaced by hydroxy groups.
Synonyms:exact_synonym: 2,3,5,6-tetrachlorobenzene-1,4-diol
 related_synonym: 2,3,5,6-Tetrachlorohydroquinone;   2,3,5,6-tetrachloro-1,4-benzenediol;   Formula=C6H2Cl4O2;   InChI=1S/C6H2Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11/h11-12H;   InChIKey=STOSPPMGXZPHKP-UHFFFAOYSA-N;   SMILES=Oc1c(Cl)c(Cl)c(O)c(Cl)c1Cl;   TeCH;   dihydro-p-chloranil;   tetrachloro-p-benzohydroquinone
 alt_id: CHEBI:15217;   CHEBI:26891;   CHEBI:9472
 xref: Beilstein:1876374;   CAS:87-87-6;   Gmelin:279912;   KEGG:C03434;   KNApSAcK:C00007485
 xref_mesh: MESH:C044578
 xref: UM-BBD_compID:c0327
 cyclic_relationship: is_conjugate_acid_of CHEBI:57994


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tetrachlorohydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO 2,3,5,6-tetrachlorohydroquinone results in decreased activity of ACHE protein CTD PMID:30905860 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ar androgen receptor multiple interactions ISO 2,3,5,6-tetrachlorohydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2,3,5,6-tetrachlorohydroquinone results in decreased expression of BCL2 protein CTD PMID:11064002 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity ISO 2,3,5,6-tetrachlorohydroquinone results in increased activity of CASP3 protein CTD PMID:30905860 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cse1l chromosome segregation 1 like decreases expression ISO 2,3,5,6-tetrachlorohydroquinone results in decreased expression of CSE1L protein CTD PMID:11064002 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 2,3,5,6-tetrachlorohydroquinone results in increased expression of PCNA protein CTD PMID:12669308 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 multiple interactions ISO TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,3,5,6-tetrachlorohydroquinone results in increased expression of TNF mRNA CTD PMID:12669308 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ttr transthyretin affects binding EXP 2,3,5,6-tetrachlorohydroquinone binds to TTR protein CTD PMID:2043046 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      chemical role 19422
        antioxidant 16120
          hydroquinone 1002
            chlorohydroquinones 10
              tetrachlorohydroquinone 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                organic aromatic compound 19341
                                  phenols 18609
                                    benzenediols 9132
                                      benzenediol 1169
                                        hydroquinone 1002
                                          chlorohydroquinones 10
                                            tetrachlorohydroquinone 10
paths to the root