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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tetrachlorohydroquinone
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Accession:CHEBI:17042 term browser browse the term
Definition:A tetrachlorobenzene that is 1,2,4,5-tetrachlorobenzene in which the hydrogens at positions 3 and 6 are replaced by hydroxy groups.
Synonyms:exact_synonym: 2,3,5,6-tetrachlorobenzene-1,4-diol
 related_synonym: 2,3,5,6-Tetrachlorohydroquinone;   2,3,5,6-tetrachloro-1,4-benzenediol;   Formula=C6H2Cl4O2;   InChI=1S/C6H2Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11/h11-12H;   InChIKey=STOSPPMGXZPHKP-UHFFFAOYSA-N;   SMILES=Oc1c(Cl)c(Cl)c(O)c(Cl)c1Cl;   TeCH;   dihydro-p-chloranil;   tetrachloro-p-benzohydroquinone
 alt_id: CHEBI:15217;   CHEBI:26891;   CHEBI:9472
 xref: Beilstein:1876374;   CAS:87-87-6;   Gmelin:279912;   KEGG:C03434;   KNApSAcK:C00007485
 xref_mesh: MESH:C044578
 xref: UM-BBD_compID:c0327
 cyclic_relationship: is_conjugate_acid_of CHEBI:57994


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tetrachlorohydroquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO 2,3,5,6-tetrachlorohydroquinone results in decreased activity of ACHE protein CTD PMID:30905860 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Ar androgen receptor multiple interactions ISO 2,3,5,6-tetrachlorohydroquinone inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2,3,5,6-tetrachlorohydroquinone results in decreased expression of BCL2 protein CTD PMID:11064002 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases activity ISO 2,3,5,6-tetrachlorohydroquinone results in increased activity of CASP3 protein CTD PMID:30905860 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cse1l chromosome segregation 1 like decreases expression ISO 2,3,5,6-tetrachlorohydroquinone results in decreased expression of CSE1L protein CTD PMID:11064002 NCBI chr 3:163,664,074...163,702,074
Ensembl chr 3:163,664,136...163,702,060
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO 2,3,5,6-tetrachlorohydroquinone results in increased expression of PCNA protein CTD PMID:12669308 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 multiple interactions ISO TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET1 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr20:27,359,122...27,438,039
Ensembl chr20:27,366,213...27,437,427
JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 multiple interactions ISO TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased chemical synthesis of 5-hydroxymethylcytosine]; TET2 protein affects the reaction [2,3,5,6-tetrachlorohydroquinone results in increased oxidation of 5-Methylcytosine] CTD PMID:24214992 NCBI chr 2:238,719,389...238,802,975
Ensembl chr 2:238,720,835...238,803,024
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2,3,5,6-tetrachlorohydroquinone results in increased expression of TNF mRNA CTD PMID:12669308 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ttr transthyretin affects binding EXP 2,3,5,6-tetrachlorohydroquinone binds to TTR protein CTD PMID:2043046 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      chemical role 19351
        antioxidant 14255
          hydroquinone 878
            chlorohydroquinones 10
              tetrachlorohydroquinone 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      carbon group element atom 19679
                        carbon atom 19668
                          organic molecular entity 19668
                            organic molecule 19596
                              organic cyclic compound 19407
                                organic aromatic compound 19233
                                  phenols 18178
                                    benzenediols 6086
                                      benzenediol 1045
                                        hydroquinone 878
                                          chlorohydroquinones 10
                                            tetrachlorohydroquinone 10
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