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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chitin
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Accession:CHEBI:17029 term browser browse the term
Definition:An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
Synonyms:exact_synonym: (1->4)-2-acetamido-2-deoxy-beta-D-glucan
 related_synonym: Formula=H2O(C8H13NO5)n;   [1,4-(N-Acetyl-beta-D-glucosaminyl)]n;   [4)-beta-D-GlcpNAc(1->]n;   beta-1,4-Poly-N-acetyl-D-glucosamine
 alt_id: CHEBI:13962;   CHEBI:23099;   CHEBI:3596
 xref: CAS:1398-61-4;   KEGG:C00461;   KEGG:G10483
 xref_mesh: MESH:D002686



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chitin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chit1 chitinase 1 affects binding ISO CHIT1 protein binds to Chitin CTD PMID:16005164 NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of IGF1R mRNA CTD PMID:30041514 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA CTD PMID:30041514 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Muc1 mucin 1, cell surface associated affects binding
multiple interactions
ISO [Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein
[[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] which results in increased uptake of Docetaxel; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] which results in increased uptake of Protein Synthesis Inhibitors
CTD PMID:30041514 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of STAT3 mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA CTD PMID:30041514 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA CTD PMID:30041514 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        pharmaceutical 19565
          drug 19565
            vulnerary 1005
              chitin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            heteroorganic entity 19548
                              organochalcogen compound 19303
                                organooxygen compound 19217
                                  carbohydrates and carbohydrate derivatives 15307
                                    carbohydrate 15307
                                      carbohydrate derivative 14311
                                        amino sugar 1365
                                          amino monosaccharide 1360
                                            hexosamine 1360
                                              N-acyl-hexosamine 1144
                                                N-acylglucosamine 1144
                                                  chitin 6
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