Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dTMP
go back to main search page
Accession:CHEBI:17013 term browser browse the term
Definition:The neutral species of thymidine 5'-monophosphate (2'-deoxythymidine 5'-monophosphate).
Synonyms:exact_synonym: 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate)
 related_synonym: (dT)1;   5'-TMP;   5'-Thymidylic acid;   5-methyl-dUMP;   Formula=C10H15N2O8P;   InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1;   InChIKey=GYOZYWVXFNDGLU-XLPZGREQSA-N;   SMILES=Cc1cn([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)c(=O)[nH]c1=O;   THYMIDINE-5'-PHOSPHATE;   TMP;   Thymidine monophosphate;   Thymidylate;   Thymidylic acid;   deoxyribosylthymine monophosphate;   ribothymidine 5'-monophosphate;   thymidine 5'-(dihydrogen phosphate);   thymidine 5'-phosphoric acid;   thymidine-5'-monophosphoric acid
 alt_id: CHEBI:10529;   CHEBI:14092;   CHEBI:15246;   CHEBI:45759;   CHEBI:45772;   CHEBI:45926;   CHEBI:46013;   CHEBI:46036;   CHEBI:47711;   CHEBI:63549
 xref: Beilstein:47541;   CAS:365-07-1;   DrugBank:DB01643;   HMDB:HMDB0001227;   KEGG:C00364;   KNApSAcK:C00019637
 xref_mesh: MESH:D013938
 xref: PDBeChem:TMPdF10;   PDBeChem:TdF10;   PMID:22512654;   PMID:22761426;   PMID:23149755;   PMID:23288848;   PMID:23362972;   PMID:23501933;   PMID:23518161;   PMID:2559771;   PMID:7110140;   PMID:8647821;   Reaxys:47541;   Wikipedia:Thymidine_monophosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:46960;   is_enantiomer_of CHEBI:42112


show annotations for term's descendants           Sort by:
 
dTMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Thymidine Monophosphate] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate CTD PMID:29258758 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        biochemical role 19311
          metabolite 19293
            fundamental metabolite 12653
              dTMP 2
                5,6-dihydrothymidine 5'-monophosphate 0
                dTMP 3'-end residue + 0
                dTMP 5'-end residue + 0
                p-nitrophenyl thymidine 5'-monophosphate 0
                thymidine 5'-monophosphate residue + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      chalcogen 19394
                        oxygen atom 19357
                          oxygen molecular entity 19357
                            hydroxides 19080
                              oxoacid 18279
                                pnictogen oxoacid 10309
                                  phosphorus oxoacid 9231
                                    phosphoric acids 7952
                                      phosphoric acid 7952
                                        phosphoric acid derivative 7632
                                          phosphate 7632
                                            organic phosphate 7631
                                              carbohydrate phosphate 1714
                                                phospho sugar 1639
                                                  aldose phosphate 1637
                                                    aldopentose phosphate 1631
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-monophosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-monophosphate 3
                                                                  thymidine 5'-monophosphate 2
                                                                    dTMP 2
                                                                      5,6-dihydrothymidine 5'-monophosphate 0
                                                                      dTMP 3'-end residue + 0
                                                                      dTMP 5'-end residue + 0
                                                                      p-nitrophenyl thymidine 5'-monophosphate 0
                                                                      thymidine 5'-monophosphate residue + 0
paths to the root