Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dTMP
go back to main search page
Accession:CHEBI:17013 term browser browse the term
Definition:The neutral species of thymidine 5'-monophosphate (2'-deoxythymidine 5'-monophosphate).
Synonyms:exact_synonym: 2'-deoxy-5-methyluridine 5'-(dihydrogen phosphate)
 related_synonym: (dT)1;   5'-TMP;   5'-Thymidylic acid;   5-methyl-dUMP;   Formula=C10H15N2O8P;   InChI=1S/C10H15N2O8P/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1;   InChIKey=GYOZYWVXFNDGLU-XLPZGREQSA-N;   SMILES=Cc1cn([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)c(=O)[nH]c1=O;   THYMIDINE-5'-PHOSPHATE;   TMP;   Thymidine monophosphate;   Thymidylate;   Thymidylic acid;   deoxyribosylthymine monophosphate;   ribothymidine 5'-monophosphate;   thymidine 5'-(dihydrogen phosphate);   thymidine 5'-phosphoric acid;   thymidine-5'-monophosphoric acid
 alt_id: CHEBI:10529;   CHEBI:14092;   CHEBI:15246;   CHEBI:45759;   CHEBI:45772;   CHEBI:45926;   CHEBI:46013;   CHEBI:46036;   CHEBI:47711;   CHEBI:63549
 xref: Beilstein:47541;   CAS:365-07-1;   DrugBank:DB01643;   HMDB:HMDB0001227;   KEGG:C00364;   KNApSAcK:C00019637
 xref_mesh: MESH:D013938
 xref: PDBeChem:TMPdF10;   PDBeChem:TdF10;   PMID:22512654;   PMID:22761426;   PMID:23149755;   PMID:23288848;   PMID:23362972;   PMID:23501933;   PMID:23518161;   PMID:2559771;   PMID:7110140;   PMID:8647821;   Reaxys:47541;   Wikipedia:Thymidine_monophosphate
 cyclic_relationship: is_conjugate_acid_of CHEBI:46960;   is_enantiomer_of CHEBI:42112



show annotations for term's descendants           Sort by:
 
dTMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Thymidine Monophosphate] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Fluorouracil results in decreased activity of TYMS protein] which results in decreased abundance of Thymidine Monophosphate CTD PMID:29258758 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20039
    role 19990
      biological role 19989
        biochemical role 19612
          metabolite 19594
            fundamental metabolite 12799
              dTMP 2
                5,6-dihydrothymidine 5'-monophosphate 0
                dTMP 3'-end residue + 0
                dTMP 5'-end residue + 0
                p-nitrophenyl thymidine 5'-monophosphate 0
                thymidine 5'-monophosphate residue + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20039
    subatomic particle 20037
      composite particle 20037
        hadron 20037
          baryon 20037
            nucleon 20037
              atomic nucleus 20037
                atom 20037
                  main group element atom 19938
                    p-block element atom 19938
                      chalcogen 19666
                        oxygen atom 19638
                          oxygen molecular entity 19638
                            hydroxides 19369
                              oxoacid 18670
                                pnictogen oxoacid 10746
                                  phosphorus oxoacid 9742
                                    phosphoric acids 8547
                                      phosphoric acid 8547
                                        phosphoric acid derivative 8249
                                          phosphate 8249
                                            organic phosphate 8248
                                              carbohydrate phosphate 1741
                                                phospho sugar 1666
                                                  aldose phosphate 1664
                                                    aldopentose phosphate 1656
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-monophosphate 3
                                                                pyrimidine 2'-deoxyribonucleoside 5'-monophosphate 3
                                                                  thymidine 5'-monophosphate 2
                                                                    dTMP 2
                                                                      5,6-dihydrothymidine 5'-monophosphate 0
                                                                      dTMP 3'-end residue + 0
                                                                      dTMP 5'-end residue + 0
                                                                      p-nitrophenyl thymidine 5'-monophosphate 0
                                                                      thymidine 5'-monophosphate residue + 0
paths to the root