Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propane-1,2-diol
go back to main search page
Accession:CHEBI:16997 term browser browse the term
Definition:The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.
Synonyms:related_synonym: 1,2-Propanediol;   1,2-Propylenglykol;   1,2-dihydroxypropane;   2-hydroxypropanol;   CH3CH(OH)CH2OH;   Formula=C3H8O2;   HOCH2CH(OH)CH3;   HOCH2CH(OH)Me;   InChI=1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3;   InChIKey=DNIAPMSPPWPWGF-UHFFFAOYSA-N;   MeCH(OH)CH2OH;   PPD;   Propylene glycol;   SMILES=CC(O)CO;   alpha-propyleneglycol;   isopropylene glycol;   methyl glycol;   methylethyl glycol;   methylethylene glycol;   monopropylene glycol
 alt_id: CHEBI:14899;   CHEBI:8469
 xref: CAS:57-55-6;   DrugBank:DB01839;   Drug_Central:4024;   HMDB:HMDB0001881;   KEGG:C00583;   KEGG:D00078;   KNApSAcK:C00007410;   LINCS:LSM-36856
 xref_mesh: MESH:D019946
 xref: PMID:15665701;   PMID:16078503;   PMID:18346395;   PMID:18845115;   PMID:21616561;   PPDB:1304;   Reaxys:1340498;   VSDB:1304;   Wikipedia:Propylene_glycol


show annotations for term's descendants           Sort by:
 
propane-1,2-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC2 mRNA CTD PMID:17934960 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC3 mRNA CTD PMID:17934960 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO [Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC4 mRNA CTD PMID:17934960 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of ARHGEF26 mRNA CTD PMID:28065790 NCBI chr 2:27,107,263...27,236,336
Ensembl chr 2:27,107,318...27,236,672
JBrowse link
G Arl15 ADP-ribosylation factor like GTPase 15 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of ARL15 mRNA CTD PMID:28065790 NCBI chr 2:45,668,852...46,053,167
Ensembl chr 2:45,668,969...46,050,564
JBrowse link
G Cers6 ceramide synthase 6 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of CERS6 mRNA CTD PMID:28065790 NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
JBrowse link
G Ddhd2 DDHD domain containing 2 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of DDHD2 mRNA CTD PMID:28065790 NCBI chr16:71,090,096...71,120,713
Ensembl chr16:71,090,045...71,118,552
JBrowse link
G Gh1 growth hormone 1 affects folding ISO Propylene Glycol affects the folding of GH1 protein CTD PMID:11064379 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of GOSR2 mRNA CTD PMID:28065790 NCBI chr10:91,735,772...91,756,123
Ensembl chr10:91,736,780...91,756,081
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased secretion of IL6 protein; [Nicotine co-treated with Propylene Glycol co-treated with Glycerol] results in increased secretion of IL6 protein CTD PMID:28065790 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of LTN1 mRNA CTD PMID:28065790 NCBI chr11:27,023,328...27,080,575
Ensembl chr11:27,022,986...27,080,701
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK1 protein; Quercetin promotes the reaction [[Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK1 protein] CTD PMID:21216973 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK3 protein; Quercetin promotes the reaction [[Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:21216973 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Olr325 olfactory receptor 325 multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of OR4D6 mRNA CTD PMID:28065790 NCBI chr 1:228,545,913...228,546,857
Ensembl chr 1:228,545,913...228,546,857
JBrowse link
G Pklr pyruvate kinase L/R multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol co-treated with Flavoring Agents] results in increased expression of PKLR mRNA CTD PMID:28065790 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Tfrc transferrin receptor multiple interactions ISO [Nicotine co-treated with Propylene Glycol co-treated with Glycerol] results in increased expression of TFRC mRNA CTD PMID:28065790 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK1 protein; [Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK3 protein; Quercetin promotes the reaction [[Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK1 protein]; Quercetin promotes the reaction [[Propylene Glycol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:21216973 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        aetiopathogenetic role 18951
          allergen 16937
            propane-1,2-diol 17
              (R)-propane-1,2-diol 0
              (S)-propane-1,2-diol + 0
              2-hydroxypropyl dihydrogen phosphate 0
              2-hydroxypropyl methacrylate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      chalcogen 19391
                        oxygen atom 19353
                          oxygen molecular entity 19353
                            hydroxides 19103
                              organic hydroxy compound 18658
                                polyol 7814
                                  diol 2729
                                    glycol 2459
                                      propanediol 1115
                                        propane-1,2-diols 1115
                                          propane-1,2-diol 17
                                            (R)-propane-1,2-diol 0
                                            (S)-propane-1,2-diol + 0
                                            2-hydroxypropyl dihydrogen phosphate 0
                                            2-hydroxypropyl methacrylate 0
paths to the root