Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxalic acid
go back to main search page
Accession:CHEBI:16995 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.
Synonyms:related_synonym: Ethandisaeure;   Ethanedioic acid;   Formula=C2H2O4;   H2ox;   HOOCCOOH;   InChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6);   InChIKey=MUBZPKHOEPUJKR-UHFFFAOYSA-N;   Oxalsaeure;   SMILES=OC(=O)C(O)=O;   ethane-1,2-dioic acid
 alt_id: CHEBI:25730;   CHEBI:44583;   CHEBI:7811
 xref: Beilstein:385686;   CAS:144-62-7;   DrugBank:DB03902;   Gmelin:2208;   HMDB:HMDB0002329;   KEGG:C00209;   KNApSAcK:C00001198;   LIPID_MAPS_instance:LMFA01170031
 xref_mesh: MESH:D019815
 xref: MetaCyc:OXALATE;   PDBeChem:OXD;   PMID:15587083;   PMID:22735334;   Reaxys:385686;   Wikipedia:Oxalic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:132952;   is_conjugate_acid_of CHEBI:46904


show annotations for term's descendants           Sort by:
 
oxalic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor decreases activity
multiple interactions
EXP Oxalic Acid results in decreased activity of AHR protein
Zinc inhibits the reaction [Oxalic Acid results in decreased activity of AHR protein]
CTD PMID:2160969 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cat catalase decreases activity ISO Oxalic Acid results in decreased activity of CAT protein CTD PMID:24145091 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
ISO Oxalic Acid results in increased expression of CCL2 mRNA
resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CCL2 mRNA]
CTD PMID:24145091 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression
ISO resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CYBA mRNA] CTD PMID:24145091 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases expression
ISO resveratrol inhibits the reaction [Oxalic Acid results in increased expression of NCF1 mRNA] CTD PMID:24145091 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression
ISO resveratrol inhibits the reaction [Oxalic Acid results in increased expression of SPP1 mRNA] CTD PMID:24145091 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO Oxalic Acid results in increased expression of TGFB1 protein
resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFB1 protein]
CTD PMID:24145091 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression
multiple interactions
ISO Oxalic Acid results in increased expression of TGFBR1 protein
resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFBR1 protein]
CTD PMID:24145091 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFBR2 protein] CTD PMID:24145091 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              algal metabolite 13582
                oxalic acid 9
                  11beta,13-dihydro-8-deoxylactucin 15-oxalate 0
                  11beta,13-dihydrolactucin 15-oxalate 0
                  11beta,13-dihydrolactucopicrin 15-oxalate 0
                  5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylic acid 0
                  8-deoxylactucin 15-oxalate 0
                  L-alpha-amino-gamma-oxalylaminobutyric acid 0
                  Methyl oxalate 0
                  allyl octadecyl oxalate 0
                  lactucin 15-oxalate 0
                  lactucopicrin 15-oxalate 0
                  oxalo group 0
                  oxalooxy group 0
                  oxalyl group 0
                  oxalyl-CoA 0
                  oxamide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      dicarboxylic acids and O-substituted derivatives 10272
                                        dicarboxylic acid 10265
                                          alpha,omega-dicarboxylic acid 2774
                                            oxalic acid 9
                                              11beta,13-dihydro-8-deoxylactucin 15-oxalate 0
                                              11beta,13-dihydrolactucin 15-oxalate 0
                                              11beta,13-dihydrolactucopicrin 15-oxalate 0
                                              5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylic acid 0
                                              8-deoxylactucin 15-oxalate 0
                                              L-alpha-amino-gamma-oxalylaminobutyric acid 0
                                              Methyl oxalate 0
                                              allyl octadecyl oxalate 0
                                              lactucin 15-oxalate 0
                                              lactucopicrin 15-oxalate 0
                                              oxalo group 0
                                              oxalooxy group 0
                                              oxalyl group 0
                                              oxalyl-CoA 0
                                              oxamide + 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.