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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:D-ribose
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Accession:CHEBI:16988 term browser browse the term
Definition:A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde.
Synonyms:exact_synonym: D-ribo-pentose
 related_synonym: D-Rib;   Formula=C5H10O5
 alt_id: CHEBI:13011;   CHEBI:21078
 xref: DrugBank:DB01936;   PMID:24404872;   PMID:24752650
 cyclic_relationship: is_enantiomer_of CHEBI:46997



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2'-deoxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein; Deoxycytidine inhibits the reaction [[9-deaza-9-(3-thienylmethyl)guanine co-treated with Deoxyguanosine] results in increased activity of CASP3 protein] CTD PMID:9297556 PMID:9403342 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO CYP1A1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]; CYP3A4 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity ISO Deoxyguanosine analog results in decreased activity of MGMT protein CTD PMID:17880193 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
JBrowse link
2-deoxy-alpha-D-ribose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase increases abundance ISO TYMP protein results in increased abundance of 2-deoxyribose 1-phosphate CTD PMID:11103787 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003
JBrowse link
2-deoxy-D-ribofuranose 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tymp thymidine phosphorylase increases abundance ISO TYMP protein results in increased abundance of 2-deoxyribose 1-phosphate CTD PMID:11103787 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003
JBrowse link
3'-phospho-5'-adenylyl sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of diosbulbin B] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A analog] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]]; [NADP co-treated with Uridine Diphosphate Glucuronic Acid co-treated with Phosphoadenosine Phosphosulfate] promotes the reaction [[Enzymes and Coenzymes results in increased metabolism of saikogenin A] inhibits the reaction [ABCB11 protein results in increased transport of Taurodeoxycholic Acid]] CTD PMID:35101544 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G P2ry1 purinergic receptor P2Y1 decreases activity ISO Phosphoadenosine Phosphosulfate results in decreased activity of P2RY1 protein CTD PMID:22273509 NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases sulfation
ISO 2,2',3,4,4',5',6-heptabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; [NQO1 protein co-treated with NADP co-treated with Phosphoadenosine Phosphosulfate co-treated with SULT1A1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Halogenated Diphenyl Ethers analog inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; pentabrominated diphenyl ether 100 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; Pentachlorophenol inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]; tribromodiphenyl ether 28 inhibits the reaction [[Estradiol co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of SULT1A1 protein]
SULT1A1 protein results in increased sulfation of Phosphoadenosine Phosphosulfate
CTD PMID:11425650 PMID:16601080 PMID:20545351 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO [Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol; Celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol]; SULT2A1 protein affects the metabolism of [Phosphoadenosine Phosphosulfate co-treated with Ethinyl Estradiol] CTD PMID:15483193 NCBI chr 1:84,582,011...84,639,001 JBrowse link
3-iodobenzyl-5'-N-methylcarboxamidoadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora3 adenosine A3 receptor multiple interactions EXP
ISO
2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]]; 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]
[N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Dizocilpine Maleate; [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Scopolamine; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein
CTD PMID:12672554 PMID:15452191 PMID:19966059 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein] CTD PMID:16116186 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression
decreases response to substance
ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of BIRC3 mRNA
BIRC3 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
CTD PMID:16088125 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance ISO BIRC5 protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine CTD PMID:16088125 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA] CTD PMID:15452191 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Il12a interleukin 12A multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] CTD PMID:16116186 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
JBrowse link
G Il12b interleukin 12B multiple interactions ISO N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]; Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]]; Wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] CTD PMID:16116186 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 decreases response to substance
decreases expression
ISO NAIP protein results in decreased susceptibility to N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine
N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of NAIP mRNA
CTD PMID:16088125 NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:33,241,521...33,276,859
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:15452191 PMID:19966059 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions EXP N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA] CTD PMID:15452191 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of SLC9A1 protein] CTD PMID:15452191 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:150,860,228...150,913,517
JBrowse link
5'-S-methyl-5'-thioadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of Acta2 mRNA in Mdr2-/- mouse liver and liver myofibroblasts RGD PMID:21209952 RGD:153297773 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Adora2b adenosine A2B receptor multiple interactions ISO 5'-S-methyl-5'-thioadenosine enhances the reaction [lipopolysaccharide increases expression of Adora2b mRNA in mouse liver myofibroblasts] RGD PMID:21209952 RGD:153297773 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions
ISO 5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein
IL7 protein inhibits the reaction [5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein]
CTD PMID:31712395 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of Ccl2 mRNA in Mdr2-/- mouse liver and myofibroblasts RGD PMID:21209952 RGD:153297773 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of cyclin-D1 mRNA in Mdr2-/- mouse liver myofibroblasts RGD PMID:21209952 RGD:153297773 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO 5'-methylthioadenosine results in decreased expression of COL1A1 mRNA
5'-S-methyl-5'-thioadenosine decreases expression of Col1a1 mRNA in Mdr2-/- mouse liver and liver myofibroblasts
CTD
RGD
PMID:15983038 PMID:21209952 RGD:153297773 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO 5'-methylthioadenosine results in decreased expression of COL1A2 mRNA CTD PMID:15983038 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of 5'-methylthioadenosine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 5'-methylthioadenosine]
CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248
JBrowse link
G Ifng interferon gamma multiple interactions
decreases secretion
ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IFNG mRNA]
5'-methylthioadenosine results in decreased secretion of IFNG protein
CTD PMID:17080400 PMID:31712395 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Ifnl1 interferon, lambda 1 multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IFNL1 mRNA] CTD PMID:37611859 NCBI chr 1:92,926,184...92,927,830 JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL1B mRNA] CTD PMID:17080400 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases secretion
ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL2 mRNA]
5'-methylthioadenosine results in decreased secretion of IL2 protein
CTD PMID:17080400 PMID:31712395 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
JBrowse link
G Il33 interleukin 33 multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL33 mRNA] CTD PMID:37545493 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of IL6 mRNA]
5'-S-methyl-5'-thioadenosine decreases expression of Il6 mRNA in Mdr2-/- mouse liver
CTD
RGD
PMID:17080400 PMID:21209952 RGD:153297773 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Il7 interleukin 7 multiple interactions ISO IL7 protein inhibits the reaction [5'-methylthioadenosine results in decreased phosphorylation of AKT1 protein] CTD PMID:31712395 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of JunD protein in Mdr2-/- mouse liver myofibroblasts RGD PMID:21209952 RGD:153297773 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148
JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO 5'-methylthioadenosine inhibits the reaction [fumonisin B1 results in increased expression of LTB mRNA] CTD PMID:17080400 NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
JBrowse link
G Mdm4 MDM4 regulator of p53 multiple interactions ISO 5'-methylthioadenosine affects the splicing of and affects the expression of MDM4 mRNA alternative form CTD PMID:31712395 NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of Ki-67 protein in Mdr2-/- mouse liver RGD PMID:21209952 RGD:153297773 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of MMP13 mRNA in Mdr2-/- mouse liver RGD PMID:21209952 RGD:153297773 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO 5'-methylthioadenosine results in decreased phosphorylation of MTOR protein CTD PMID:31712395 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of iNOS mRNA in Mdr2-/- mouse liver RGD PMID:21209952 RGD:153297773 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO 5'-methylthioadenosine results in decreased phosphorylation of RPS6 protein CTD PMID:31712395 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of Tgfb1 mRNA in Mdr2-/- mouse liver myofibroblasts RGD PMID:21209952 RGD:153297773 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of Tgfb2 mRNA in Mdr2-/- mouse liver and myofibroblasts RGD PMID:21209952 RGD:153297773 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856
JBrowse link
G Tnc tenascin C decreases expression ISO 5'-S-methyl-5'-thioadenosine decreases expression of tenascin-C mRNA in Mdr2-/- mouse liver RGD PMID:21209952 RGD:153297773 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 5'-S-methyl-5'-thioadenosine inhibits the reaction [lipopolysaccharide increases expression of Tnf-alpha mRNA and protein in mouse liver myofibroblasts] RGD PMID:21209952 RGD:153297773 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 increases expression ISO 5'-methylthioadenosine results in increased expression of TP53 protein CTD PMID:31712395 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
5-azacytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan decreases expression ISO Azacitidine results in decreased expression of ACAN mRNA CTD PMID:39531065 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] CTD PMID:22841775 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO Azacitidine results in decreased expression of ADAMTS1 mRNA CTD PMID:20823114 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
JBrowse link
G Adrb1 adrenoceptor beta 1 affects expression ISO Azacitidine affects the expression of ADRB1 mRNA CTD PMID:19002953 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237
JBrowse link
G Adrb2 adrenoceptor beta 2 affects expression
multiple interactions
ISO Azacitidine affects the expression of ADRB2 mRNA
Azacitidine inhibits the reaction [Particulate Matter results in decreased expression of ADRB2 mRNA]
CTD PMID:19002953 PMID:30986742 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Azacitidine results in increased expression of AFP mRNA CTD PMID:27590069 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 increases expression ISO Azacitidine results in increased expression of AGGF1 mRNA CTD PMID:19194470 NCBI chr 2:28,354,073...28,380,794
Ensembl chr 2:28,354,073...28,380,759
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
multiple interactions
ISO Azacitidine results in increased expression of AHR mRNA
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]
CTD PMID:12927368 PMID:17682057 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Ak5 adenylate kinase 5 increases expression ISO Azacitidine results in increased expression of AK5 mRNA CTD PMID:20823114 NCBI chr 2:244,057,240...244,241,372
Ensembl chr 2:244,057,240...244,241,366
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22841775 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alad aminolevulinate dehydratase decreases expression ISO Azacitidine results in decreased expression of ALAD mRNA CTD PMID:19194470 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
JBrowse link
G Alb albumin decreases expression
increases expression
ISO Azacitidine results in decreased expression of ALB protein
Azacitidine results in increased expression of ALB mRNA
CTD PMID:27590069 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of ALDH3A1 mRNA]] CTD PMID:17682057 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
JBrowse link
G Andpro androgen regulated protein increases expression ISO Azacitidine results in increased expression of CST4 mRNA CTD PMID:20823114 NCBI chr 3:157,171,739...157,178,262
Ensembl chr 3:157,171,740...157,178,104
JBrowse link
G Anxa1 annexin A1 decreases expression EXP Azacitidine results in decreased expression of ANXA1 protein CTD PMID:17105402 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
JBrowse link
G App amyloid beta precursor protein decreases methylation
multiple interactions
ISO Azacitidine results in decreased methylation of APP promoter
Azacitidine results in increased expression of and results in increased cleavage of APP protein; Betaine inhibits the reaction [Azacitidine results in decreased methylation of APP promoter]; Betaine inhibits the reaction [Azacitidine results in increased expression of and results in increased cleavage of APP protein]
CTD PMID:19635394 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Aqp5 aquaporin 5 decreases methylation
increases expression
multiple interactions
ISO Azacitidine results in decreased methylation of AQP5 promoter
Azacitidine results in increased expression of AQP5 protein
[Azacitidine results in decreased methylation of AQP5 promoter] which results in increased expression of AQP5 mRNA; Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]
CTD PMID:17198683 NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:132,601,059...132,605,062
JBrowse link
G Aqp9 aquaporin 9 multiple interactions
increases expression
ISO [Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of arsenic trioxide; HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA] CTD PMID:25953102 NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240
JBrowse link
G Ar androgen receptor multiple interactions
increases expression
ISO [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to bicalutamide; [Azacitidine analog results in increased expression of AR protein] which results in increased susceptibility to Dihydrotestosterone CTD PMID:18324645 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 increases expression ISO Azacitidine results in increased expression of ARHGAP35 mRNA CTD PMID:20823114 NCBI chr 1:86,330,566...86,447,414
Ensembl chr 1:86,330,566...86,447,414
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO Azacitidine results in decreased expression of ARHGEF2 mRNA CTD PMID:20823114 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
JBrowse link
G Art1 ADP-ribosyltransferase 1 increases expression ISO Azacitidine results in increased expression of ART1 mRNA CTD PMID:20823114 NCBI chr 1:165,890,032...165,899,154
Ensembl chr 1:165,890,086...165,899,146
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Azacitidine results in increased expression of ASB2 mRNA CTD PMID:20823114 NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:128,239,552...128,266,321
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Azacitidine results in decreased expression of ATP2B1 mRNA CTD PMID:20823114 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression ISO Azacitidine results in increased expression of ATP6V0C mRNA CTD PMID:20823114 NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions
EXP Azacitidine results in increased expression of BAD mRNA
[Azacitidine co-treated with entinostat] results in increased expression of BAD mRNA
CTD PMID:21224363 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP [Azacitidine co-treated with entinostat] results in increased expression of BAK1 mRNA
Azacitidine results in increased expression of BAK1 mRNA
CTD PMID:21224363 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA] CTD PMID:32278510 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 decreases expression ISO Azacitidine results in decreased expression of BCAT1 mRNA CTD PMID:20823114 NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
Azacitidine results in decreased expression of BCL2 mRNA; Azacitidine results in decreased expression of BCL2 protein
CTD PMID:32278510 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects expression
ISO [metacept-1 co-treated with Azacitidine] results in decreased expression of BCL2L1
[Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein
CTD PMID:18443271 PMID:19148494 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Bcl2l13 Bcl2-like 13 increases expression ISO Azacitidine results in increased expression of BCL2L13 mRNA CTD PMID:20823114 NCBI chr 4:155,728,284...155,785,058
Ensembl chr 4:155,728,284...155,781,158
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
decreases methylation
multiple interactions
ISO Azacitidine results in increased expression of BDNF mRNA
Azacitidine results in decreased methylation of BDNF promoter
Tetrodotoxin inhibits the reaction [Azacitidine results in decreased methylation of BDNF promoter]; Tetrodotoxin inhibits the reaction [Azacitidine results in increased expression of BDNF mRNA]
CTD PMID:18184782 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression
increases expression
EXP
ISO
Azacitidine results in decreased expression of BGLAP protein
Azacitidine results in increased expression of OCN mRNA
CTD PMID:18037191 PMID:39531065 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
JBrowse link
G Bicd1 BICD cargo adaptor 1 decreases expression ISO Azacitidine results in decreased expression of BICD1 mRNA CTD PMID:20823114 NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:184,210,363...184,357,391
JBrowse link
G Bik BCL2-interacting killer multiple interactions
increases expression
EXP [Azacitidine co-treated with entinostat] results in increased expression of BIK mRNA
Azacitidine results in increased expression of BIK mRNA
CTD PMID:21224363 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317
JBrowse link
G Bmp15 bone morphogenetic protein 15 increases expression ISO Azacitidine results in increased expression of BMP15 mRNA CTD PMID:23395740 NCBI chr  X:18,840,943...18,846,006
Ensembl chr  X:18,840,829...18,847,438
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Azacitidine results in increased expression of BNIP3 mRNA CTD PMID:25446377 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962
JBrowse link
G Bok BCL2 family apoptosis regulator BOK multiple interactions
increases expression
EXP [Azacitidine co-treated with entinostat] results in increased expression of BOK mRNA
Azacitidine results in increased expression of BOK mRNA
CTD PMID:21224363 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA CTD PMID:18720364 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
JBrowse link
G C17h6orf62 similar to human chromosome 6 open reading frame 62 increases expression ISO Azacitidine results in increased expression of C6ORF62 mRNA CTD PMID:19194470 NCBI chr17:40,684,236...40,695,874
Ensembl chr17:40,684,236...40,704,043
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression ISO Azacitidine results in increased expression of C3AR1 mRNA CTD PMID:19194470 NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323
JBrowse link
G Calca calcitonin-related polypeptide alpha decreases methylation ISO Azacitidine results in decreased methylation of CALCA promoter CTD PMID:19299654 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529
JBrowse link
G Cald1 caldesmon 1 increases expression ISO Azacitidine results in increased expression of CALD1 mRNA CTD PMID:20823114 NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085
JBrowse link
G Calhm2 calcium homeostasis modulator family member 2 increases expression
multiple interactions
ISO Azacitidine results in increased expression of CALHM2 mRNA
Cisplatin affects the reaction [Azacitidine results in increased expression of CALHM2 mRNA]
CTD PMID:36336710 NCBI chr 1:255,963,661...255,969,387
Ensembl chr 1:255,963,663...255,969,387
JBrowse link
G Casp3 caspase 3 affects expression
increases activity
increases expression
multiple interactions
ISO Azacitidine affects the expression of CASP3 protein
5-azacytidine co-treated with doxorubicin increases activity of CASP3 protein in lung cancer cells
Azacitidine results in increased expression of CASP3 mRNA
[metacept-1 co-treated with Azacitidine] results in increased expression of CASP3
CTD
RGD
PMID:18443271 PMID:19148494 PMID:23395740 PMID:24356455 RGD:153344603 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases expression ISO Azacitidine results in increased expression of CASP8 mRNA CTD PMID:18082045 PMID:23395740 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases expression ISO Azacitidine results in increased expression of CASP9 mRNA CTD PMID:23395740 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccna1 cyclin A1 multiple interactions
decreases expression
ISO Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter]; Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter]; Azacitidine promotes the reaction [H4C16 protein modified form binds to CCNA1 promoter]
Azacitidine results in decreased expression of CCNA1 mRNA
CTD PMID:17698632 NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA
Azacitidine results in decreased expression of CCNA2 mRNA
CTD PMID:18720364 PMID:20823114 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA
Azacitidine results in increased expression of CCNB1 protein
CTD PMID:18720364 PMID:20607034 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Azacitidine results in increased expression of CCND1 mRNA CTD PMID:20823114 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccnd2 cyclin D2 affects methylation
multiple interactions
ISO Azacitidine affects the methylation of CCND2 promoter
[Azacitidine affects the methylation of CCND2 promoter] which affects the expression of CCND2 mRNA
CTD PMID:17016690 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301
JBrowse link
G Ccng2 cyclin G2 decreases expression ISO Azacitidine results in decreased expression of CCNG2 mRNA CTD PMID:21245298 NCBI chr14:15,088,694...15,097,190
Ensembl chr14:15,088,695...15,096,206
JBrowse link
G Cd274 CD274 molecule multiple interactions ISO Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]] CTD PMID:32894642 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA CTD PMID:18720364 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
JBrowse link
G Cdc42bpa CDC42 binding protein kinase alpha decreases expression ISO Azacitidine results in decreased expression of CDC42BPA mRNA CTD PMID:20823114 NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681
JBrowse link
G Cdh1 cadherin 1 decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of CDH1 promoter
Azacitidine results in increased expression of CDH1 mRNA
CTD PMID:17520682 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Cdh2 cadherin 2 increases expression EXP Azacitidine results in increased expression of CDH2 mRNA CTD PMID:18037191 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
increases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA
Azacitidine analog results in increased expression of CDK1 protein
CTD PMID:18324645 PMID:18720364 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Azacitidine analog results in decreased expression of CDK2 protein CTD PMID:18324645 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Azacitidine analog results in decreased expression of CDK4 protein CTD PMID:18324645 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO
EXP
Azacitidine analog results in increased expression of CDKN1A protein; Azacitidine results in increased expression of CDKN1A mRNA
[Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A
CTD PMID:18324645 PMID:19148494 PMID:20823114 PMID:21224363 PMID:25015661 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Azacitidine results in increased expression of CDKN1C mRNA CTD PMID:19194470 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
decreases methylation
affects methylation
increases expression
EXP
ISO
[Azacitidine co-treated with entinostat] results in decreased methylation of CDKN2A gene; [Azacitidine co-treated with entinostat] results in increased expression of CDKN2A mRNA
Azacitidine inhibits the reaction [Particulate Matter results in increased methylation of CDKN2A promoter]
Hydroxyurea inhibits the reaction [Azacitidine results in decreased methylation of CDKN2A gene]
Azacitidine affects the methylation of CDKN2A gene
Azacitidine results in increased expression of CDKN2A mRNA
CTD PMID:17686055 PMID:18443271 PMID:21224363 PMID:22355787 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B decreases methylation
multiple interactions
affects response to substance
ISO Azacitidine results in decreased methylation of CDKN2B promoter
[metacept-1 co-treated with Azacitidine] results in increased expression of CDKN2B
CDKN2B promoter modified form affects the susceptibility to Azacitidine
CTD PMID:17611569 PMID:19148494 PMID:19194470 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of CEBPA promoter
Azacitidine results in increased expression of CEBPA mRNA
CTD PMID:19194470 PMID:27590069 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
JBrowse link
G Cenpa centromere protein A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA CTD PMID:18720364 NCBI chr 6:31,420,062...31,431,703 JBrowse link
G Cenpf centromere protein F multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA CTD PMID:18720364 NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
JBrowse link
G Cenpo centromere protein O increases expression ISO Azacitidine results in increased expression of CENPO mRNA CTD PMID:19194470 NCBI chr 6:32,923,127...32,937,879
Ensembl chr 6:32,908,025...32,937,853
JBrowse link
G Chat choline O-acetyltransferase increases expression ISO Azacitidine results in increased expression of CHAT mRNA; Azacitidine results in increased expression of CHAT protein CTD PMID:19151599 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416
JBrowse link
G Chga chromogranin A decreases expression ISO Azacitidine results in decreased expression of CHGA protein CTD PMID:20607034 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237
JBrowse link
G Chit1 chitinase 1 increases expression ISO Azacitidine results in increased expression of CHIT1 mRNA CTD PMID:20823114 NCBI chr13:48,117,886...48,165,645
Ensembl chr13:48,145,893...48,165,639
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 affects expression ISO Azacitidine affects the expression of CHRM1 mRNA CTD PMID:19002953 NCBI chr 1:214,996,180...215,012,136
Ensembl chr 1:214,995,872...215,020,602
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects expression ISO Azacitidine affects the expression of CHRM2 mRNA CTD PMID:19002953 NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464
JBrowse link
G Chst14 carbohydrate sulfotransferase 14 increases expression EXP Azacitidine results in increased expression of CHST14 mRNA CTD PMID:27415467 NCBI chr 3:126,370,348...126,372,405
Ensembl chr 3:126,370,348...126,372,777
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions
increases expression
ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]
Azacitidine results in increased expression of CIITA mRNA
CTD PMID:18829986 PMID:20823114 NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342
JBrowse link
G Cldn10 claudin 10 decreases expression ISO Azacitidine results in decreased expression of CLDN10 mRNA CTD PMID:19194470 NCBI chr15:102,269,858...102,361,589
Ensembl chr15:102,269,858...102,361,589
JBrowse link
G Cldn6 claudin 6 increases expression
decreases methylation
multiple interactions
ISO Azacitidine results in increased expression of CLDN6 mRNA
Azacitidine results in decreased methylation of CLDN6 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN6 promoter
CTD PMID:18661270 NCBI chr10:13,213,837...13,218,578
Ensembl chr10:13,213,956...13,218,581
JBrowse link
G Cldn7 claudin 7 multiple interactions
decreases expression
ISO Cisplatin affects the reaction [Azacitidine results in decreased expression of CLDN7 mRNA] CTD PMID:36336710 NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905
JBrowse link
G Cldn8 claudin 8 increases expression ISO Azacitidine results in increased expression of CLDN8 mRNA CTD PMID:18661270 NCBI chr11:41,362,081...41,364,330 JBrowse link
G Cldn9 claudin 9 decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of CLDN9 promoter
[trichostatin A co-treated with Azacitidine] results in decreased methylation of CLDN9 promoter
Azacitidine results in increased expression of CLDN9 mRNA
CTD PMID:18661270 NCBI chr10:13,218,728...13,220,159
Ensembl chr10:13,218,729...13,220,178
JBrowse link
G Cnnm2 cyclin and CBS domain divalent metal cation transport mediator 2 decreases expression ISO Azacitidine results in decreased expression of CNNM2 mRNA CTD PMID:19194470 NCBI chr 1:255,585,063...255,709,455
Ensembl chr 1:255,585,095...255,704,849
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Azacitidine results in increased expression of COL14A1 mRNA CTD PMID:19194470 NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein] CTD PMID:22841775 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Col6a3 collagen type VI alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL6A3 mRNA CTD PMID:20823114 NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990
JBrowse link
G Col9a3 collagen type IX alpha 3 chain decreases expression ISO Azacitidine results in decreased expression of COL9A3 mRNA CTD PMID:18033690 NCBI chr 3:188,089,337...188,112,034
Ensembl chr 3:188,089,403...188,112,270
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Azacitidine results in increased expression of COX6A2 mRNA CTD PMID:20823114 NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
JBrowse link
G Cpe carboxypeptidase E increases expression ISO Azacitidine results in increased expression of CPE mRNA CTD PMID:20823114 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524
JBrowse link
G Cplx1 complexin 1 increases expression ISO Azacitidine results in increased expression of CPLX1 mRNA CTD PMID:20823114 NCBI chr14:1,329,073...1,360,781
Ensembl chr14:1,329,032...1,360,769
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter] CTD PMID:19155497 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 increases expression EXP Azacitidine results in increased expression of CREB3L4 mRNA CTD PMID:27415467 NCBI chr 2:177,987,981...177,994,568
Ensembl chr 2:177,987,981...177,993,485
JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO Azacitidine results in decreased expression of CREM mRNA CTD PMID:20823114 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
JBrowse link
G Cryaa crystallin, alpha A increases expression EXP Azacitidine results in increased expression of CRYAA protein CTD PMID:17105402 NCBI chr20:9,784,872...9,788,656
Ensembl chr20:9,784,857...9,788,654
JBrowse link
G Cryab crystallin, alpha B increases expression EXP Azacitidine results in increased expression of CRYAB protein CTD PMID:17105402 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
JBrowse link
G Csf1 colony stimulating factor 1 increases expression EXP Azacitidine results in increased expression of CSF1 mRNA CTD PMID:17156202 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468
JBrowse link
G Csn1s1 casein alpha s1 increases expression ISO Azacitidine results in increased expression of CSN1S1 mRNA CTD PMID:20823114 NCBI chr14:20,622,858...20,638,849 JBrowse link
G Cst3 cystatin C increases expression ISO Azacitidine results in increased expression of CST3 mRNA CTD PMID:20823114 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of CXCL12 promoter
Azacitidine results in increased expression of CXCL12 mRNA; Azacitidine results in increased expression of CXCL12 protein
CTD PMID:19748759 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
[Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]
Azacitidine results in increased expression of CYP1A1 mRNA
CTD PMID:11281733 PMID:12927368 PMID:17682057 PMID:27590069 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
Azacitidine results in increased expression of CYP1A2 mRNA
CTD PMID:12927368 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Azacitidine results in increased expression of CYP1B1 mRNA
CTD PMID:12927368 PMID:27590069 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Azacitidine results in increased expression of CYP3A4 mRNA CTD PMID:27590069 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Cyth1 cytohesin 1 increases expression ISO Azacitidine results in increased expression of CYTH1 mRNA CTD PMID:19194470 NCBI chr10:103,901,376...103,984,496
Ensembl chr10:103,864,804...103,984,383
JBrowse link
G Dapk1 death associated protein kinase 1 affects methylation ISO Azacitidine affects the methylation of DAPK1 promoter CTD PMID:17557868 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581
JBrowse link
G Dcn decorin multiple interactions
decreases expression
ISO Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein]
Azacitidine results in decreased expression of DCN mRNA
CTD PMID:20823114 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
JBrowse link
G Des desmin increases expression
multiple interactions
EXP
ISO
Azacitidine results in increased expression of DES mRNA; Azacitidine results in increased expression of DES protein
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA
CTD PMID:18037191 PMID:20823114 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347
JBrowse link
G Dhx9 DExH-box helicase 9 decreases expression ISO Azacitidine results in decreased expression of DHX9 mRNA CTD PMID:20823114 NCBI chr13:68,152,813...68,189,580
Ensembl chr13:68,152,813...68,189,546
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression ISO Azacitidine results in decreased expression of DIO2 mRNA CTD PMID:20823114 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases methylation ISO Azacitidine results in decreased methylation of DLK1 promoter CTD PMID:19194470 NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529
JBrowse link
G Dlx5 distal-less homeobox 5 increases expression ISO Azacitidine results in increased expression of DLX5 mRNA CTD PMID:17085970 NCBI chr 4:35,965,579...35,969,973
Ensembl chr 4:35,965,579...35,969,845
JBrowse link
G Dlx6 distal-less homeobox 6 increases expression ISO Azacitidine results in increased expression of DLX6 mRNA CTD PMID:20823114 NCBI chr 4:35,951,005...35,956,354
Ensembl chr 4:35,951,005...35,956,354
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression
ISO
EXP
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Arsenic Trioxide promotes the reaction [Azacitidine results in decreased expression of DNMT1 protein]; Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]
Azacitidine results in decreased expression of DNMT1 mRNA
[Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein; [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein
CTD PMID:19139132 PMID:19723570 PMID:21224363 PMID:28901456 PMID:35066776 More... NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions
decreases expression
ISO Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter]
Azacitidine results in decreased expression of DNMT3A mRNA
CTD PMID:35066776 PMID:39331569 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions
decreases expression
ISO Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter]
Azacitidine results in decreased expression of DNMT3B mRNA
CTD PMID:35066776 PMID:39331569 NCBI chr 3:162,590,777...162,629,313
Ensembl chr 3:162,604,037...162,629,313
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases methylation
multiple interactions
decreases response to substance
ISO Azacitidine results in decreased methylation of DPYD promoter
[Azacitidine results in decreased methylation of DPYD promoter] which results in increased expression of DPYD mRNA
DPYD protein results in decreased susceptibility to Azacitidine
CTD PMID:15501990 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Azacitidine results in increased expression of DUSP1 mRNA CTD PMID:20823114 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Azacitidine results in increased expression of DUSP6 mRNA CTD PMID:21245298 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA] CTD PMID:19451745 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 decreases expression ISO Azacitidine results in decreased expression of EEF1A1 mRNA CTD PMID:20823114 NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072
JBrowse link
G Efna3 ephrin A3 increases expression ISO Azacitidine results in increased expression of EFNA3 mRNA CTD PMID:20823114 NCBI chr 2:177,026,928...177,035,838
Ensembl chr 2:177,026,933...177,044,843
JBrowse link
G Egr2 early growth response 2 increases expression ISO Azacitidine results in increased expression of EGR2 mRNA CTD PMID:20823114 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748
JBrowse link
G Eno2 enolase 2 decreases expression ISO Azacitidine results in decreased expression of ENO2 protein CTD PMID:20607034 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 increases expression ISO Azacitidine results in increased expression of ENTPD1 mRNA CTD PMID:20823114 NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:249,374,836...249,502,317
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Azacitidine results in increased expression of ESR1 protein CTD PMID:22558281 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [ETS1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Azacitidine results in decreased expression of EYA1 mRNA CTD PMID:20823114 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Azacitidine results in decreased expression of FADS2 mRNA CTD PMID:20823114 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
JBrowse link
G Fam8a1 family with sequence similarity 8, member A1 increases expression ISO Azacitidine results in increased expression of FAM8A1 mRNA CTD PMID:19194470 NCBI chr17:18,232,834...18,241,736
Ensembl chr17:18,232,834...18,241,703
JBrowse link
G Faslg Fas ligand increases response to substance ISO Azacitidine results in increased susceptibility to FASLG protein CTD PMID:18829727 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Azacitidine results in increased expression of FBLN1 mRNA CTD PMID:21245298 NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
JBrowse link
G Fen1 flap structure-specific endonuclease 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNA CTD PMID:18720364 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
JBrowse link
G Fgf7 fibroblast growth factor 7 decreases expression ISO Azacitidine results in decreased expression of FGF7 mRNA CTD PMID:20823114 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
JBrowse link
G Filip1l filamin A interacting protein 1-like decreases expression ISO Azacitidine results in decreased expression of FILIP1L mRNA CTD PMID:20823114 NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA CTD PMID:20823114 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
JBrowse link
G Foxp3 forkhead box P3 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein; [Azacitidine results in decreased methylation of FOXP3 gene] which results in increased expression of FOXP3 protein CTD PMID:18493985 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894
JBrowse link
G Ftl1 ferritin light chain 1 decreases expression EXP Azacitidine results in decreased expression of FTL1 protein CTD PMID:17105402 NCBI chr 1:105,072,858...105,074,705
Ensembl chr  X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Azacitidine results in increased expression of FYN mRNA CTD PMID:21245298 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Azacitidine results in increased expression of GABRB1 mRNA CTD PMID:19194470 NCBI chr14:36,434,339...36,917,920
Ensembl chr14:36,434,352...36,902,893
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of GADD45A promoter
[Azacitidine results in increased expression of GADD45A protein] which results in increased susceptibility to docetaxel
Azacitidine results in increased expression of GADD45A mRNA; Azacitidine results in increased expression of GADD45A protein
CTD PMID:19190346 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO Azacitidine promotes the reaction [Depsipeptides results in increased expression of GADD45B] CTD PMID:18225533 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718
JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP Azacitidine results in increased expression of GATA4 mRNA; Azacitidine results in increased expression of GATA4 protein CTD PMID:18037191 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609
JBrowse link
G Gbp2 guanylate binding protein 2 decreases expression ISO Azacitidine results in decreased expression of GBP2 mRNA CTD PMID:20823114 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 decreases expression ISO Azacitidine results in decreased expression of GCNT2 mRNA CTD PMID:20823114 NCBI chr17:24,002,592...24,107,339
Ensembl chr17:24,002,597...24,106,989
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO Azacitidine results in increased expression of GDF9 mRNA CTD PMID:23395740 NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
decreases expression
EXP
ISO
Azacitidine results in increased expression of GJA1 protein
Azacitidine results in decreased expression of GJA1 mRNA
CTD PMID:18037191 PMID:20823114 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Glb1 galactosidase, beta 1 increases expression ISO Azacitidine results in increased expression of GLB1 protein CTD PMID:39531065 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326
JBrowse link
G Gng7 G protein subunit gamma 7 affects methylation ISO Azacitidine affects the methylation of GNG7 promoter CTD PMID:18219292 NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:9,348,218...9,411,923
JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO Azacitidine results in increased expression of GPKOW mRNA CTD PMID:20823114 NCBI chr  X:17,463,521...17,478,298
Ensembl chr  X:17,463,525...17,478,298
JBrowse link
G Gpnmb glycoprotein nmb decreases expression ISO Azacitidine results in decreased expression of GPNMB mRNA CTD PMID:20823114 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO 5-azacytidine increases expression of GPX3 mRNA in epithelial cells of stomach RGD PMID:16229808 RGD:151665354 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases methylation ISO Azacitidine results in decreased methylation of GRIN2B gene CTD PMID:18618247 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570
JBrowse link
G Guk1 guanylate kinase 1 increases expression ISO Azacitidine results in increased expression of GUK1 mRNA CTD PMID:20823114 NCBI chr10:44,471,075...44,488,332
Ensembl chr10:44,471,085...44,479,355
JBrowse link
G Gzmb granzyme B multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein] CTD PMID:19394699 NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469
JBrowse link
G H1f0 H1.0 linker histone increases expression ISO Azacitidine results in increased expression of H1-0 protein CTD PMID:16006241 NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006
JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions
ISO
EXP
Azacitidine results in increased expression of H2AX protein
Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]
CTD PMID:17991895 PMID:25015661 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G H3f4 H3.4 histone, cluster member multiple interactions ISO Azacitidine promotes the reaction [H3-4 protein modified form binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr10:44,240,282...44,240,842 JBrowse link
G Hgd homogentisate 1, 2-dioxygenase increases expression ISO Azacitidine results in increased expression of HGD mRNA CTD PMID:20823114 NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Azacitidine results in increased expression of HGF mRNA CTD PMID:19194470 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
JBrowse link
G Hhex hematopoietically expressed homeobox increases expression ISO Azacitidine results in increased expression of HHEX mRNA CTD PMID:27590069 NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Azacitidine results in increased expression of HMGA1 mRNA CTD PMID:20823114 NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,613,471...5,620,593
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression
multiple interactions
ISO Azacitidine results in increased expression of HMGA2 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]
CTD PMID:21245298 NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:57,765,675...57,880,341
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression
multiple interactions
ISO Azacitidine results in decreased expression of HMGB1 mRNA
Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]
CTD PMID:32278510 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Hnf1a HNF1 homeobox A decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of HNF1A promoter
HNF1A mutant form inhibits the reaction [Azacitidine results in increased expression of AQP9 mRNA]
Azacitidine results in increased expression of HNF1A mRNA; Azacitidine results in increased expression of HNF1A protein
CTD PMID:25953102 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO Azacitidine results in increased expression of HNF4A mRNA CTD PMID:27590069 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758
JBrowse link
G Hoxa1 homeobox A1 multiple interactions
increases expression
ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA]
Azacitidine results in increased expression of HOXA1 mRNA
CTD PMID:20823114 NCBI chr 4:82,586,505...82,589,209
Ensembl chr 4:82,586,505...82,589,209
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of HPGD gene
trichostatin A promotes the reaction [Azacitidine results in increased expression of HPGD mRNA]
CTD PMID:19584167 NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects expression ISO Azacitidine affects the expression of HSD3B1 mRNA CTD PMID:18033690 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsf1 heat shock transcription factor 1 decreases activity ISO Azacitidine results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Azacitidine results in increased expression of HSPA6 mRNA CTD PMID:19194470 NCBI chr13:85,805,911...85,807,052 JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO Azacitidine results in increased expression of ID1 mRNA CTD PMID:19194470 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
JBrowse link
G Id3 inhibitor of DNA binding 3 increases expression ISO Azacitidine results in increased expression of ID3 mRNA CTD PMID:19194470 NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein; [Azacitidine results in decreased methylation of CIITA promoter] promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]; [Azacitidine results in increased expression of KIR2DL4 protein] which results in increased secretion of IFNG protein CTD PMID:18829986 PMID:18945643 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions
increases expression
ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein]
Azacitidine results in increased expression of IGFBP1 mRNA
CTD PMID:20823114 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Azacitidine results in increased expression of IGFBP4 mRNA CTD PMID:20823114 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
JBrowse link
G Il12b interleukin 12B increases expression ISO Azacitidine results in increased expression of IL12B mRNA CTD PMID:20823114 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Azacitidine results in increased expression of IL1B mRNA
Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 mRNA]]; Azacitidine inhibits the reaction [Oleanolic Acid inhibits the reaction [IL1B protein results in increased expression of CD274 protein]]
CTD PMID:17156202 PMID:32894642 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of GZMB protein]; Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
JBrowse link
G Il4 interleukin 4 affects methylation ISO Azacitidine affects the methylation of IL4 promoter CTD PMID:18158872 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il6 interleukin 6 affects secretion
affects methylation
ISO Azacitidine affects the secretion of IL6 protein
Azacitidine affects the methylation of IL6 promoter
CTD PMID:18158872 PMID:18443271 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Il6r interleukin 6 receptor affects expression
multiple interactions
ISO [Azacitidine affects the expression of IL6R protein] which affects the expression of BCL2L1 protein; Azacitidine affects the expression of IL6R mRNA
[Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein
CTD PMID:18443271 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 increases expression ISO Azacitidine results in increased expression of ISCA1 mRNA CTD PMID:19194470 NCBI chr17:4,910,816...4,923,478
Ensembl chr17:4,910,795...4,923,476
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Azacitidine results in decreased expression of ITGB1 mRNA CTD PMID:20823114 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
JBrowse link
G Itgb2 integrin subunit beta 2 decreases expression ISO Azacitidine results in decreased expression of ITGB2 mRNA CTD PMID:19194470 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182
JBrowse link
G Itprid2 ITPR interacting domain containing 2 increases expression ISO Azacitidine results in increased expression of ITPRID2 mRNA CTD PMID:20823114 NCBI chr 3:84,943,572...84,980,993
Ensembl chr 3:84,939,808...84,980,899
JBrowse link
G Kdr kinase insert domain receptor increases expression EXP Azacitidine results in increased expression of KDR mRNA CTD PMID:18037191 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of KIF2C mRNA CTD PMID:18720364 NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
JBrowse link
G Kir3dl1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 increases expression
decreases methylation
ISO Azacitidine results in increased expression of KIR3DL1 mRNA; Azacitidine results in increased expression of KIR3DL1 protein
Azacitidine results in decreased methylation of KIR3DL1 promoter
CTD PMID:18945643 PMID:19394699 NCBI chr 1:78,756,035...78,796,961
Ensembl chr 1:78,757,394...78,796,715
JBrowse link
G Klf6 KLF transcription factor 6 increases expression
multiple interactions
ISO Azacitidine results in increased expression of KLF6 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]
CTD PMID:21245298 NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases expression ISO Azacitidine analog results in increased expression of KLK3 protein CTD PMID:18324645 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
JBrowse link
G Krt19 keratin 19 increases expression ISO Azacitidine results in increased expression of KRT19 mRNA CTD PMID:20823114 NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952
JBrowse link
G Krt32 keratin 32 increases expression ISO Azacitidine results in increased expression of KRT32 mRNA CTD PMID:20823114 NCBI chr10:85,513,951...85,520,978
Ensembl chr10:85,513,951...85,520,978
JBrowse link
G Krt8 keratin 8 multiple interactions
increases expression
ISO Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA]
Azacitidine results in increased expression of KRT8 mRNA
CTD PMID:20823114 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
JBrowse link
G Lama1 laminin subunit alpha 1 affects localization ISO Azacitidine affects the localization of LAMA1 protein CTD PMID:18033690 NCBI chr 9:115,139,548...115,263,620
Ensembl chr 9:115,139,548...115,264,251
JBrowse link
G Lamb2 laminin subunit beta 2 increases expression ISO Azacitidine results in increased expression of LAMB2 mRNA CTD PMID:20823114 NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090
JBrowse link
G Ldhb lactate dehydrogenase B increases expression ISO Azacitidine results in increased expression of LDHB mRNA CTD PMID:23437403 NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408
JBrowse link
G Lims1 LIM zinc finger domain containing 1 increases expression ISO Azacitidine results in increased expression of LIMS1 mRNA CTD PMID:19194470 NCBI chr20:26,851,364...26,961,607
Ensembl chr20:26,852,996...26,961,606
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression ISO Azacitidine results in decreased expression of LITAF mRNA CTD PMID:19194470 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930
JBrowse link
G Ltb4r leukotriene B4 receptor decreases expression ISO Azacitidine results in decreased expression of LTB4R mRNA CTD PMID:20823114 NCBI chr15:33,233,120...33,235,636
Ensembl chr15:33,232,820...33,235,637
JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Azacitidine results in increased expression of LYZ mRNA CTD PMID:19194470 NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 decreases expression ISO Azacitidine results in decreased expression of MAD1L1 mRNA CTD PMID:19194470 NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567
JBrowse link
G Mafb MAF bZIP transcription factor B increases expression
multiple interactions
ISO Azacitidine results in increased expression of MAFB mRNA
Cisplatin affects the reaction [Azacitidine results in increased expression of MAFB mRNA]
CTD PMID:36336710 NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975
JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Azacitidine results in decreased expression of MAP1A mRNA CTD PMID:20823114 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO Azacitidine results in decreased expression of MAP2K5 mRNA CTD PMID:20823114 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:72,520,617...72,747,373
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Azacitidine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO 5-azacytidine decreases expression of MCL1 protein in lung cancer cells RGD PMID:24356455 RGD:153344603 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MCM5 mRNA CTD PMID:18720364 NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 increases expression ISO Azacitidine results in increased expression of MDC1 mRNA CTD PMID:20823114 NCBI chr20:2,898,496...2,914,960
Ensembl chr20:2,900,308...2,914,960
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO Azacitidine results in increased expression of MDM2 mRNA CTD PMID:20823114 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
JBrowse link
G Mecp2 methyl CpG binding protein 2 multiple interactions ISO Azacitidine inhibits the reaction [MECP2 protein binds to CCNA1 promoter] CTD PMID:17698632 NCBI chr  X:156,932,481...156,995,981
Ensembl chr  X:156,941,234...156,943,560
JBrowse link
G Mef2a myocyte enhancer factor 2a increases expression
affects expression
ISO Azacitidine results in increased expression of MEF2A
Azacitidine affects the expression of MEF2A protein
CTD PMID:12094073 PMID:19002953 NCBI chr 1:130,258,083...130,392,819
Ensembl chr 1:130,260,339...130,392,162
JBrowse link
G Mef2d myocyte enhancer factor 2D affects expression
increases expression
ISO Azacitidine affects the expression of MEF2D protein
Azacitidine results in increased expression of MEF2D
CTD PMID:12094073 PMID:19002953 NCBI chr 2:175,904,332...175,933,451
Ensembl chr 2:175,903,959...175,930,760
JBrowse link
G Megf6 multiple EGF-like-domains 6 decreases expression ISO Azacitidine results in decreased expression of MEGF6 mRNA CTD PMID:19194470 NCBI chr 5:170,020,699...170,121,557
Ensembl chr 5:170,020,778...170,121,554
JBrowse link
G Mesd mesoderm development LRP chaperone decreases expression EXP Azacitidine results in decreased expression of MESD protein CTD PMID:17105402 NCBI chr 1:147,275,904...147,289,134
Ensembl chr 1:147,275,396...147,289,134
JBrowse link
G Mfap2 microfibril associated protein 2 decreases expression ISO Azacitidine results in decreased expression of MFAP2 mRNA CTD PMID:20823114 NCBI chr 5:158,595,121...158,603,283
Ensembl chr 5:158,597,512...158,610,656
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing affects expression ISO Azacitidine affects the expression of MFGE8 mRNA CTD PMID:18033690 NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
decreases methylation
ISO Azacitidine results in increased expression of MGMT mRNA
Azacitidine results in decreased methylation of MGMT protein
CTD PMID:7511991 PMID:12807730 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
JBrowse link
G Mir193a microRNA 193a increases expression ISO 5-azacytidine increases expression of MIR193A in liver cells
5-azacytidine increases expression of MIR193a RNA in lung cancer cells
RGD PMID:28036298 PMID:24356455 RGD:153344564, RGD:153344603 NCBI chr10:65,170,306...65,170,417 JBrowse link
G Mir23b microRNA 23b increases expression ISO 5-azacytidine increases expression of MIR23B miRNA in liver cells RGD PMID:28036298 RGD:153344564 NCBI chr17:1,819,386...1,819,482 JBrowse link
G Mir497 microRNA 497 increases expression
multiple interactions
decreases methylation
ISO Azacitidine results in increased expression of MIR497 mRNA
Azacitidine inhibits the reaction [DNMT1 protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3A protein binds to MIR497 promoter]; Azacitidine inhibits the reaction [DNMT3B protein binds to MIR497 promoter]
Azacitidine results in decreased methylation of MIR497 promoter
CTD PMID:35066776 NCBI chr10:55,450,171...55,450,239
Ensembl chr10:55,450,162...55,450,241
JBrowse link
G Mir9-3 microRNA 9-3 increases expression ISO 5-azacytidine increases expression of MIR9-3 in lung cancer cells RGD PMID:24356455 RGD:153344603 NCBI chr 1:142,849,400...142,849,489 JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MKI67 mRNA CTD PMID:18720364 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Azacitidine results in increased expression of MMP1 mRNA CTD PMID:20823114 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO metacept-1 inhibits the reaction [Azacitidine results in increased expression of MMP9] CTD PMID:19148494 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Morf4l2 mortality factor 4 like 2 decreases expression ISO Azacitidine results in decreased expression of MORF4L2 mRNA CTD PMID:20823114 NCBI chr  X:104,874,850...104,885,946
Ensembl chr  X:104,852,693...104,892,855
JBrowse link
G Mov10l1 Mov10 like RNA helicase 1 increases expression ISO Azacitidine results in increased expression of MOV10L1 mRNA CTD PMID:20823114 NCBI chr 7:121,949,743...122,015,042
Ensembl chr 7:121,949,822...122,015,042
JBrowse link
G Msrb2 methionine sulfoxide reductase B2 increases expression ISO Azacitidine results in increased expression of MSRB2 mRNA CTD PMID:19194470 NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Azacitidine results in decreased expression of MTHFD2 mRNA CTD PMID:20823114 NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
JBrowse link
G Mtrex Mtr4 exosome RNA helicase increases expression ISO Azacitidine results in increased expression of MTREX mRNA CTD PMID:20823114 NCBI chr 2:46,233,528...46,293,827
Ensembl chr 2:46,194,647...46,293,827
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO Azacitidine analog results in decreased expression of MYC mRNA
MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
CTD PMID:18045574 PMID:19451745 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Myf5 myogenic factor 5 increases expression ISO Azacitidine results in increased expression of MYF5 mRNA CTD PMID:18938140 NCBI chr 7:44,689,407...44,692,638
Ensembl chr 7:44,689,407...44,692,638
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Azacitidine results in increased expression of MYH7 mRNA; Azacitidine results in increased expression of MYH7 protein CTD PMID:17105402 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194
JBrowse link
G Myl2 myosin light chain 2 increases expression EXP Azacitidine results in increased expression of MYL2 mRNA CTD PMID:17105402 NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149
JBrowse link
G Myod1 myogenic differentiation 1 increases expression EXP
ISO
Azacitidine results in increased expression of MYOD1 mRNA CTD PMID:18037191 PMID:18938140 NCBI chr 1:106,021,161...106,023,871
Ensembl chr 1:106,021,161...106,023,871
JBrowse link
G Myog myogenin increases expression ISO Azacitidine results in increased expression of MYOG mRNA CTD PMID:18938140 NCBI chr13:48,297,476...48,300,065
Ensembl chr13:48,297,235...48,300,065
JBrowse link
G Ncam1 neural cell adhesion molecule 1 increases expression EXP Azacitidine results in increased expression of NCAM1 mRNA CTD PMID:18037191 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971
JBrowse link
G Nefl neurofilament light chain increases expression ISO Azacitidine results in increased expression of NEFL mRNA CTD PMID:20823114 NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 increases expression ISO Azacitidine results in increased expression of NFATC1 mRNA CTD PMID:20823114 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression
multiple interactions
ISO Azacitidine results in increased expression of NIBAN1 mRNA
TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA]
CTD PMID:21245298 NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
JBrowse link
G Nkx2-5 NK2 homeobox 5 increases expression ISO Azacitidine results in increased expression of NKX2-5 mRNA CTD PMID:18557828 NCBI chr10:16,844,888...16,851,458
Ensembl chr10:16,848,582...16,851,452
JBrowse link
G Nlgn3 neuroligin 3 increases expression ISO Azacitidine results in increased expression of NLGN3 mRNA CTD PMID:20823114 NCBI chr  X:70,469,251...70,497,380
Ensembl chr  X:70,469,457...70,497,379
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Azacitidine results in increased expression of NME2 protein CTD PMID:17105402 NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497
JBrowse link
G Nmi N-myc (and STAT) interactor increases expression ISO Azacitidine results in increased expression of NMI mRNA CTD PMID:21245298 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:56,811,314...56,848,717
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase increases expression ISO Azacitidine results in increased expression of NNT mRNA; Azacitidine results in increased expression of NNT protein CTD PMID:36336710 NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310
JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 decreases expression ISO Azacitidine results in decreased expression of NOM1 mRNA CTD PMID:20823114 NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036
JBrowse link
G Nphp1 nephrocystin 1 increases expression ISO Azacitidine results in increased expression of NPHP1 mRNA CTD PMID:20823114 NCBI chr 3:135,413,927...135,469,505
Ensembl chr 3:135,413,927...135,469,505
JBrowse link
G Nppa natriuretic peptide A increases expression ISO Azacitidine results in increased expression of NPPA CTD PMID:15005238 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
JBrowse link
G Nppb natriuretic peptide B increases expression ISO Azacitidine results in increased expression of NPPB CTD PMID:15005238 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of NQO1 mRNA]] CTD PMID:17682057 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [metacept-1 co-treated with Azacitidine] results in increased expression of NR4A1 CTD PMID:19148494 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 decreases expression ISO Azacitidine results in decreased expression of NRIP1 mRNA CTD PMID:20823114 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353
JBrowse link
G Nrn1 neuritin 1 decreases expression ISO Azacitidine results in decreased expression of NRN1 mRNA CTD PMID:19194470 NCBI chr17:28,335,426...28,344,354
Ensembl chr17:28,334,616...28,344,354
JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO Azacitidine results in increased expression of NT5E mRNA CTD PMID:20823114 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
JBrowse link
G Nts neurotensin decreases expression ISO Azacitidine results in decreased expression of NTS mRNA CTD PMID:20823114 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of NUSAP1 mRNA CTD PMID:18720364 NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 increases expression ISO Azacitidine results in increased expression of NXT2 mRNA CTD PMID:19194470 NCBI chr  X:110,652,434...110,659,738
Ensembl chr  X:110,652,434...110,659,737
JBrowse link
G Ocln occludin increases expression ISO Azacitidine results in increased expression of OCLN mRNA CTD PMID:18661270 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Ogfrl1 opioid growth factor receptor-like 1 increases expression ISO Azacitidine results in increased expression of OGFRL1 mRNA CTD PMID:20823114 NCBI chr 9:33,320,501...33,338,742
Ensembl chr 9:33,324,392...33,339,237
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression
decreases methylation
ISO Azacitidine results in decreased expression of OGG1 protein
Azacitidine results in decreased methylation of OGG1 promoter
CTD PMID:22064374 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
JBrowse link
G Or8b8 olfactory receptor family 8 subfamily B member 8 increases expression ISO Azacitidine results in increased expression of OR8B8 mRNA CTD PMID:20823114 NCBI chr 8:45,882,321...45,883,253
Ensembl chr 8:45,882,321...45,883,253
JBrowse link
G Oxr1 oxidation resistance 1 increases expression ISO Azacitidine results in increased expression of OXR1 mRNA CTD PMID:20823114 NCBI chr 7:74,413,609...74,850,487
Ensembl chr 7:74,413,590...74,850,487
JBrowse link
G Oxtr oxytocin receptor decreases expression ISO Azacitidine results in decreased expression of OXTR mRNA CTD PMID:21245298 NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP
ISO
Azacitidine results in increased expression of P4HB protein
Azacitidine results in increased expression of P4HB mRNA
CTD PMID:17105402 PMID:20823114 NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911
JBrowse link
G Paep progestagen associated endometrial protein decreases expression ISO Azacitidine results in decreased expression of PAEP mRNA CTD PMID:20823114 NCBI chr 3:28,929,252...28,932,592 JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 increases expression ISO Azacitidine results in increased expression of PAK1 mRNA CTD PMID:20823114 NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:161,491,847...161,637,612
JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Azacitidine results in decreased expression of PANK3 mRNA CTD PMID:19194470 NCBI chr10:20,733,191...20,757,017
Ensembl chr10:20,733,127...20,757,015
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO Azacitidine results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]
CTD PMID:32278510 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pax4 paired box 4 increases expression ISO Azacitidine results in increased expression of PAX4 mRNA CTD PMID:18949370 NCBI chr 4:58,023,873...58,032,265
Ensembl chr 4:58,023,914...58,028,858
JBrowse link
G Pcdh18 protocadherin 18 decreases expression ISO Azacitidine results in decreased expression of PCDH18 mRNA CTD PMID:20823114 NCBI chr 2:135,982,929...135,996,917
Ensembl chr 2:135,983,144...135,996,826
JBrowse link
G Pcdha1 protocadherin alpha 1 affects methylation ISO Azacitidine affects the methylation of PCDHA1 promoter CTD PMID:18204046 Ensembl chr18:28,855,256...29,120,227 JBrowse link
G Pcdha10 protocadherin alpha 10 affects methylation ISO Azacitidine affects the methylation of PCDHA10 promoter CTD PMID:18204046
G Pcdha11 protocadherin alpha 11 affects methylation ISO Azacitidine affects the methylation of PCDHA11 promoter CTD PMID:18204046
G Pcdha12 protocadherin alpha 12 affects methylation ISO Azacitidine affects the methylation of PCDHA12 promoter CTD PMID:18204046 Ensembl chr18:28,855,256...29,120,227 JBrowse link
G Pcdha2 protocadherin alpha 2 affects methylation ISO Azacitidine affects the methylation of PCDHA2 promoter CTD PMID:18204046
G Pcdha3 protocadherin alpha 3 affects methylation ISO Azacitidine affects the methylation of PCDHA3 promoter CTD PMID:18204046
G Pcdha4 protocadherin alpha 4 affects methylation ISO Azacitidine affects the methylation of PCDHA4 promoter CTD PMID:18204046 NCBI chr18:28,688,274...29,120,227
Ensembl chr18:28,855,256...29,120,227
JBrowse link
G Pcdha5 protocadherin alpha 5 affects methylation ISO Azacitidine affects the methylation of PCDHA5 promoter CTD PMID:18204046
G Pcdha6 protocadherin alpha 6 affects methylation ISO Azacitidine affects the methylation of PCDHA6 promoter CTD PMID:18204046 Ensembl chr18:28,855,256...29,120,227 JBrowse link
G Pcdha7 protocadherin alpha 7 affects methylation ISO Azacitidine affects the methylation of PCDHA7 promoter CTD PMID:18204046
G Pcdha9 protocadherin alpha 9 affects methylation ISO Azacitidine affects the methylation of PCDHA8 promoter; Azacitidine affects the methylation of PCDHA9 promoter CTD PMID:18204046
G Pcdhb20 protocadherin beta 20 decreases expression ISO Azacitidine results in decreased expression of PCDHB14 mRNA CTD PMID:20823114 NCBI chr18:29,485,888...29,489,282
Ensembl chr18:29,454,999...29,489,427
JBrowse link
G Pcdhb5 protocadherin beta 5 decreases expression ISO Azacitidine results in decreased expression of PCDHB4 mRNA CTD PMID:20823114 NCBI chr18:29,302,466...29,305,048 JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
EXP Azacitidine results in decreased expression of PCNA protein
[Cisplatin co-treated with Azacitidine] results in decreased expression of PCNA protein
CTD PMID:19723570 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression ISO Azacitidine results in increased expression of PDK1 mRNA CTD PMID:20823114 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression
decreases methylation
ISO Azacitidine results in increased expression of PDK4 protein
Azacitidine results in decreased methylation of PDK4 promoter
CTD PMID:28003426 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Azacitidine results in increased expression of PECAM1 mRNA CTD PMID:18037191 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839
JBrowse link
G Pfn1 profilin 1 increases expression ISO Azacitidine results in increased expression of PFN1 mRNA CTD PMID:20823114 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611
JBrowse link
G Phactr2 phosphatase and actin regulator 2 increases expression ISO Azacitidine results in increased expression of PHACTR2 mRNA CTD PMID:20823114 NCBI chr 1:9,411,412...9,680,648
Ensembl chr 1:9,418,085...9,680,583
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha decreases expression ISO Azacitidine results in decreased expression of PIP5K1A mRNA CTD PMID:19194470 NCBI chr 2:185,317,319...185,361,859
Ensembl chr 2:185,317,319...185,360,476
JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 decreases expression ISO Azacitidine results in decreased expression of PITPNC1 mRNA CTD PMID:20823114 NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344
JBrowse link
G Pitx3 paired-like homeodomain 3 increases expression EXP Azacitidine results in increased expression of PITX3 mRNA CTD PMID:27415467 NCBI chr 1:254,942,550...254,955,325
Ensembl chr 1:254,942,608...254,955,336
JBrowse link
G Pja1 praja ring finger ubiquitin ligase 1 increases expression ISO Azacitidine results in increased expression of PJA1 mRNA CTD PMID:19194470 NCBI chr  X:68,621,101...68,626,001
Ensembl chr  X:68,620,084...68,638,407
JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel increases expression ISO Azacitidine results in increased expression of PKD2L1 mRNA CTD PMID:20823114 NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:252,982,096...253,023,359
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Azacitidine results in increased expression of PKM mRNA CTD PMID:20823114 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
JBrowse link
G Plcb1 phospholipase C beta 1 decreases methylation
decreases response to substance
increases response to substance
increases expression
ISO Azacitidine results in decreased methylation of PLCB1 promoter
PLCB1 promoter modified form results in decreased susceptibility to Azacitidine
PLCB1 mRNA results in increased susceptibility to Azacitidine; PLCB1 protein results in increased susceptibility to Azacitidine
Azacitidine results in increased expression of PLCB1 mRNA; Azacitidine results in increased expression of PLCB1 protein
CTD PMID:19805378 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646
JBrowse link
G Plpp1 phospholipid phosphatase 1 increases expression ISO Azacitidine results in increased expression of PLPP1 mRNA CTD PMID:19194470 NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:46,172,197...46,234,676
JBrowse link
G Pls3 plastin 3 decreases expression ISO Azacitidine results in decreased expression of PLS3 mRNA CTD PMID:20823114 NCBI chr  X:116,401,247...116,495,898
Ensembl chr  X:116,401,293...116,495,893
JBrowse link
G Pml PML nuclear body scaffold increases expression ISO Azacitidine results in increased expression of PML mRNA CTD PMID:19194470 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases methylation
increases expression
ISO Azacitidine results in decreased methylation of PPARG promoter
Azacitidine results in increased expression of PPARG mRNA
CTD PMID:19589179 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions
increases expression
decreases methylation
ISO Azacitidine promotes the reaction [CREB1 protein modified form binds to PPP2CA promoter]
Azacitidine results in increased expression of PPP2CA mRNA
Azacitidine results in decreased methylation of PPP2CA promoter
CTD PMID:19155497 NCBI chr10:36,856,534...36,878,789 JBrowse link
G Prdx4 peroxiredoxin 4 decreases expression EXP Azacitidine results in decreased expression of PRDX4 protein CTD PMID:17105402 NCBI chr  X:43,876,374...43,893,815
Ensembl chr  X:43,876,417...43,893,812
JBrowse link
G Prf1 perforin 1 multiple interactions ISO Azacitidine inhibits the reaction [IL2 protein results in increased secretion of PRF1 protein] CTD PMID:19394699 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,788,972...29,795,124
JBrowse link
G Prl prolactin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein CTD PMID:20823114 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
G Prom1 prominin 1 increases expression EXP Azacitidine results in increased expression of PROM1 mRNA CTD PMID:18037191 NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002
JBrowse link
G Prss12 serine protease 12 decreases expression ISO Azacitidine results in decreased expression of PRSS12 mRNA CTD PMID:20823114 NCBI chr 2:214,308,695...214,368,679
Ensembl chr 2:214,308,774...214,369,941
JBrowse link
G Psen1 presenilin 1 decreases methylation
multiple interactions
ISO Azacitidine results in decreased methylation of PSEN1 promoter
Betaine inhibits the reaction [Azacitidine results in decreased methylation of PSEN1 promoter]
CTD PMID:19635394 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter] CTD PMID:22841775 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Azacitidine results in decreased expression of PTHLH mRNA CTD PMID:20823114 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454
JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator increases expression ISO Azacitidine results in increased expression of PTPA mRNA CTD PMID:20823114 NCBI chr 3:34,087,637...34,118,100
Ensembl chr 3:34,087,575...34,162,772
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression ISO Azacitidine results in increased expression of PTPRC mRNA CTD PMID:19194470 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746
JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression EXP Azacitidine results in increased expression of PTPRO mRNA CTD PMID:14508512 NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903
JBrowse link
G Rab13 RAB13, member RAS oncogene family decreases methylation ISO Azacitidine results in decreased methylation of RAB13 promoter CTD PMID:19194470 NCBI chr 2:177,972,535...177,977,679
Ensembl chr 2:177,972,372...177,977,684
JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression ISO Azacitidine results in increased expression of RAB1B mRNA CTD PMID:20823114 NCBI chr 1:211,835,133...211,843,408
Ensembl chr 1:211,835,073...211,843,337
Ensembl chr  X:211,835,073...211,843,337
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression ISO Azacitidine results in increased expression of RACGAP1 mRNA CTD PMID:20823114 NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
JBrowse link
G Ranbp2 RAN binding protein 2 increases expression ISO Azacitidine results in increased expression of RANBP2 mRNA CTD PMID:19194470 NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571
JBrowse link
G Rasa3 RAS p21 protein activator 3 increases expression ISO Azacitidine results in increased expression of RASA3 mRNA CTD PMID:20823114 NCBI chr16:82,557,556...82,671,527
Ensembl chr16:82,557,428...82,672,984
JBrowse link
G Rcn1 reticulocalbin 1 decreases expression ISO Azacitidine results in decreased expression of RCN1 mRNA CTD PMID:20823114 NCBI chr 3:112,295,838...112,310,082
Ensembl chr 3:112,295,838...112,310,082
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization
decreases expression
ISO Azacitidine affects the localization of RELA protein
5-azacytidine decreases expression of RELA protein in lung cancer cells
CTD
RGD
PMID:18443271 PMID:24356455 RGD:153344603 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Ret ret proto-oncogene decreases expression ISO Azacitidine results in decreased expression of RET mRNA CTD PMID:20823114 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556
JBrowse link
G Rfc3 replication factor C subunit 3 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RFC3 mRNA CTD PMID:18720364 NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [trichostatin A co-treated with Azacitidine] results in increased expression of RHOB protein; Azacitidine promotes the reaction [trichostatin A results in increased expression of RHOB mRNA] CTD PMID:18047684 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
JBrowse link
G Rin1 Ras and Rab interactor 1 increases expression ISO Azacitidine results in increased expression of RIN1 mRNA CTD PMID:20823114 NCBI chr 1:211,785,107...211,789,755
Ensembl chr 1:211,784,943...211,791,368
JBrowse link
G Rpl4 ribosomal protein L4 increases expression EXP Azacitidine results in increased expression of RPL4 mRNA CTD PMID:9813173 NCBI chr 8:73,566,477...73,571,600
Ensembl chr 8:73,566,466...73,571,788
JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 increases expression ISO Azacitidine results in increased expression of RPP21 mRNA CTD PMID:20823114 NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,023,186...2,025,308
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Azacitidine results in decreased phosphorylation of RPS6 protein CTD PMID:21245298 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566
JBrowse link
G Rpsa ribosomal protein SA decreases expression ISO Azacitidine results in decreased expression of RPSA mRNA CTD PMID:20823114 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Azacitidine results in increased expression of RRM2B mRNA CTD PMID:19010910 NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670
JBrowse link
G RT1-Da RT1 class II, locus Da multiple interactions ISO [Azacitidine promotes the reaction [IFNG protein results in increased expression of CIITA mRNA]] which results in increased expression of HLA-DRA protein CTD PMID:18829986 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [RUNX1 protein binds to KIR2DL4 promoter] CTD PMID:18945643 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO Azacitidine results in decreased expression of RUNX2 mRNA CTD PMID:39531065 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
JBrowse link
G Runx3 RUNX family transcription factor 3 affects methylation ISO Azacitidine affects the methylation of RUNX3 gene CTD PMID:18058463 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835
JBrowse link
G S100a14 S100 calcium binding protein A14 decreases expression ISO Azacitidine results in decreased expression of S100A14 mRNA CTD PMID:20823114 NCBI chr 2:178,305,976...178,308,004
Ensembl chr 2:178,306,025...178,307,999
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Azacitidine results in increased expression of S100A9 mRNA CTD PMID:19194470 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870
JBrowse link
G Sall4 spalt-like transcription factor 4 affects methylation ISO Azacitidine affects the methylation of SALL4 promoter CTD PMID:17546590 NCBI chr 3:177,891,705...177,909,743
Ensembl chr 3:177,891,705...177,909,743
JBrowse link
G Scamp4 secretory carrier membrane protein 4 increases expression ISO Azacitidine results in increased expression of SCAMP4 mRNA CTD PMID:20823114 NCBI chr 7:9,752,193...9,764,614
Ensembl chr 7:9,752,193...9,778,736
JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Azacitidine results in decreased expression of SDCBP mRNA CTD PMID:20823114 NCBI chr 5:24,245,279...24,314,712
Ensembl chr 5:24,245,033...24,326,197
JBrowse link
G Sema3a semaphorin 3A increases expression ISO Azacitidine results in increased expression of SEMA3A mRNA CTD PMID:20823114 NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:22,245,322...22,535,774
JBrowse link
G Sema6c semaphorin 6C increases expression ISO Azacitidine results in increased expression of SEMA6C mRNA CTD PMID:20823114 NCBI chr 2:185,422,636...185,436,237
Ensembl chr 2:185,422,639...185,448,689
JBrowse link
G Senp3 SUMO specific peptidase 3 increases expression ISO Azacitidine results in increased expression of SENP3 mRNA CTD PMID:20823114 NCBI chr10:54,889,445...54,898,359
Ensembl chr10:54,888,847...54,898,227
JBrowse link
G Six2 SIX homeobox 2 decreases expression
multiple interactions
ISO Azacitidine results in decreased expression of SIX2 mRNA
Cisplatin affects the reaction [Azacitidine results in decreased expression of SIX2 mRNA]
CTD PMID:36336710 NCBI chr 6:14,727,756...14,734,219
Ensembl chr 6:14,727,859...14,731,941
JBrowse link
G Slbp stem-loop histone mRNA binding protein multiple interactions ISO Azacitidine inhibits the reaction [sodium arsenite results in decreased expression of SLBP mRNA] CTD PMID:25266719 NCBI chr14:81,295,479...81,306,446
Ensembl chr14:81,296,223...81,306,447
JBrowse link
G Slc28a1 solute carrier family 28 member 1 increases response to substance
multiple interactions
increases uptake
ISO SLC28A1 protein results in increased susceptibility to Azacitidine
[SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein; Sodium affects the reaction [SLC28A1 protein results in increased uptake of Azacitidine]
CTD PMID:19139132 NCBI chr 1:144,490,453...144,532,025
Ensembl chr 1:144,490,623...144,531,544
JBrowse link
G Slc29a2 solute carrier family 29 member 2 decreases expression ISO Azacitidine results in decreased expression of SLC29A2 mRNA CTD PMID:19194470 NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:211,757,000...211,764,560
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases expression
ISO [Azacitidine co-treated with Butyrates] affects the expression of SLC5A5 mRNA
Azacitidine results in increased expression of SLC5A5 mRNA
CTD PMID:16954431 PMID:17164311 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691
JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 increases expression ISO Azacitidine results in increased expression of SNU13 mRNA CTD PMID:20823114 NCBI chr 7:115,445,415...115,451,008
Ensembl chr 1:269,702,002...269,703,004
Ensembl chr 7:269,702,002...269,703,004
JBrowse link
G Socs3 suppressor of cytokine signaling 3 affects expression ISO Azacitidine affects the expression of SOCS3 protein CTD PMID:18443271 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
JBrowse link
G Sox13 SRY-box transcription factor 13 decreases expression ISO Azacitidine results in decreased expression of SOX13 mRNA CTD PMID:20823114 NCBI chr13:47,383,145...47,427,572
Ensembl chr13:47,383,145...47,435,663
JBrowse link
G Sox2 SRY-box transcription factor 2 increases expression EXP Azacitidine results in increased expression of SOX2 mRNA CTD PMID:27415467 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350
JBrowse link
G Sox8 SRY-box transcription factor 8 decreases expression ISO Azacitidine results in decreased expression of SOX8 mRNA CTD PMID:18033690 NCBI chr10:15,089,357...15,094,345
Ensembl chr10:15,089,357...15,094,345
JBrowse link
G Sox9 SRY-box transcription factor 9 affects expression
increases expression
ISO Azacitidine affects the expression of SOX9 mRNA
Azacitidine results in increased expression of SOX9 mRNA
CTD PMID:18033690 PMID:39531065 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
decreases expression
ISO Azacitidine promotes the reaction [SP1 protein binds to KIR2DL2 promoter]; Azacitidine promotes the reaction [SP1 protein binds to KIR2DL4 promoter]
Azacitidine results in decreased expression of SP1 mRNA
Azacitidine promotes the reaction [SP1 protein binds to AQP5 promoter]
CTD PMID:17198683 PMID:18945643 PMID:20823114 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO Azacitidine results in increased expression of SP7 mRNA CTD PMID:17085970 NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559
JBrowse link
G Spag5 sperm associated antigen 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of SPAG5 mRNA CTD PMID:18720364 NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression ISO Azacitidine results in decreased expression of SRPX mRNA CTD PMID:19194470 NCBI chr  X:15,349,498...15,420,389
Ensembl chr  X:15,349,440...15,420,392
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 decreases expression ISO Azacitidine results in decreased expression of SRSF7 mRNA CTD PMID:20823114 NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
JBrowse link
G Ssx2ip SSX family member 2 interacting protein increases expression ISO Azacitidine results in increased expression of SSX2IP mRNA CTD PMID:20823114 NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 increases expression ISO Azacitidine results in increased expression of ST3GAL6 mRNA CTD PMID:19194470 NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 decreases expression ISO Azacitidine results in decreased expression of ST8SIA2 mRNA CTD PMID:20823114 NCBI chr 1:137,172,354...137,247,796
Ensembl chr 1:137,172,354...137,247,792
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Azacitidine affects the expression of IL6R protein] which affects the phosphorylation of STAT3 protein CTD PMID:18443271 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO Azacitidine results in decreased expression of STC2 mRNA CTD PMID:19194470 NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447
JBrowse link
G Stk38 serine/threonine kinase 38 decreases expression ISO Azacitidine results in decreased expression of STK38 mRNA CTD PMID:20823114 NCBI chr20:7,035,923...7,070,657
Ensembl chr20:7,035,933...7,069,711
JBrowse link
G Sulf1 sulfatase 1 decreases expression ISO Azacitidine results in decreased expression of SULF1 mRNA CTD PMID:20823114 NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643
JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases expression ISO Azacitidine results in increased expression of SULT1C2 mRNA CTD PMID:19194470 NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:7,066,905...7,244,132
JBrowse link
G Tat tyrosine aminotransferase increases expression ISO Azacitidine results in increased expression of TAT mRNA CTD PMID:27590069 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
JBrowse link
G Tbc1d4 TBC1 domain family, member 4 decreases expression ISO Azacitidine results in decreased expression of TBC1D4 mRNA CTD PMID:19194470 NCBI chr15:84,670,756...84,848,876
Ensembl chr15:84,670,756...84,848,693
JBrowse link
G Tcea1 transcription elongation factor A1 decreases expression ISO Azacitidine results in decreased expression of TCEA1 mRNA CTD PMID:20823114 NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156
Ensembl chr 5:12,831,339...12,834,156
JBrowse link
G Tecpr2 tectonin beta-propeller repeat containing 2 increases expression ISO Azacitidine results in increased expression of TECPR2 mRNA CTD PMID:19194470 NCBI chr 6:135,720,765...135,823,187
Ensembl chr 6:135,720,656...135,823,187
JBrowse link
G Tek TEK receptor tyrosine kinase increases expression EXP Azacitidine results in increased expression of TEK mRNA CTD PMID:18037191 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
decreases methylation
decreases activity
ISO Azacitidine analog results in decreased expression of TERT mRNA; Azacitidine results in decreased expression of TERT mRNA
E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]; MYC protein affects the reaction [Azacitidine results in decreased activity of TERT protein]; MYC protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA]
Azacitidine results in decreased methylation of TERT promoter
CTD PMID:18045574 PMID:19451745 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 increases expression ISO Azacitidine results in increased expression of TFE3 mRNA CTD PMID:19194470 NCBI chr  X:17,401,466...17,414,829
Ensembl chr  X:17,401,466...17,414,685
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Azacitidine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein
Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in decreased expression of PTEN protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]; Azacitidine inhibits the reaction [TGFB1 protein results in increased methylation of PTEN promoter]; Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]
CTD PMID:18493985 PMID:22841775 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Thumpd1 THUMP domain containing 1 increases expression ISO Azacitidine results in increased expression of THUMPD1 mRNA CTD PMID:19194470 NCBI chr 1:183,510,242...183,516,282
Ensembl chr 1:183,431,657...183,516,282
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Azacitidine results in increased expression of TIMP1 mRNA CTD PMID:20823114 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135
JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Azacitidine results in increased expression of TJP1 mRNA CTD PMID:18661270 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 increases expression ISO Azacitidine results in increased expression of TMED3 mRNA CTD PMID:20823114 NCBI chr 8:99,121,361...99,129,653
Ensembl chr 8:99,121,361...99,129,215
JBrowse link
G Tmpo thymopoietin multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TMPO mRNA CTD PMID:18720364 NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937
JBrowse link
G Tnc tenascin C decreases expression ISO Azacitidine results in decreased expression of TNC mRNA CTD PMID:20823114 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance
EXP
ISO
Azacitidine results in increased expression of TNF mRNA
Azacitidine results in increased susceptibility to TNF protein
CTD PMID:17156202 PMID:18829727 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance ISO Azacitidine results in increased susceptibility to TNFSF10 protein CTD PMID:18829727 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP Azacitidine results in increased expression of TNNI3 protein CTD PMID:17105402 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253
JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression EXP Azacitidine results in increased expression of TNNT2 protein CTD PMID:22496879 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TOP2A mRNA; [Curcumin co-treated with Azacitidine] results in decreased expression of TOP2A mRNA CTD PMID:18348204 PMID:18720364 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
JBrowse link
G Tp53 tumor protein p53 affects activity
increases expression
ISO
EXP
Azacitidine affects the activity of TP53 protein
Azacitidine results in increased expression of TP53 mRNA; Azacitidine results in increased expression of TP53 protein
CTD PMID:16427046 PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tp73 tumor protein p73 multiple interactions ISO TP73 protein promotes the reaction [Azacitidine results in increased expression of HMGA2 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of KLF6 mRNA]; TP73 protein promotes the reaction [Azacitidine results in increased expression of NIBAN1 mRNA] CTD PMID:21245298 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552
JBrowse link
G Tpd52 tumor protein D52 increases expression EXP Azacitidine results in increased expression of TPD52 mRNA CTD PMID:27415467 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241
JBrowse link
G Tpm2 tropomyosin 2 increases expression ISO Azacitidine results in increased expression of TPM2 mRNA CTD PMID:20823114 NCBI chr 5:62,566,712...62,576,066
Ensembl chr 5:62,566,652...62,575,726
JBrowse link
G Tpo thyroid peroxidase increases expression ISO Azacitidine results in increased expression of TPO mRNA CTD PMID:17679169 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793
JBrowse link
G Tpsg1 tryptase gamma 1 decreases expression ISO Azacitidine results in decreased expression of TPSG1 mRNA CTD PMID:20823114 NCBI chr10:14,889,838...14,895,605
Ensembl chr10:14,890,734...14,894,786
JBrowse link
G Trh thyrotropin releasing hormone decreases expression ISO Azacitidine results in decreased expression of TRH mRNA CTD PMID:19194470 NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:126,299,236...126,301,762
JBrowse link
G Trib1 tribbles pseudokinase 1 decreases expression ISO Azacitidine results in decreased expression of TRIB1 mRNA CTD PMID:19194470 NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:93,095,973...93,117,480
JBrowse link
G Trim8 tripartite motif-containing 8 increases expression ISO Azacitidine results in increased expression of TRIM8 mRNA CTD PMID:19194470 NCBI chr 1:255,311,039...255,325,937
Ensembl chr 1:255,310,457...255,325,937
JBrowse link
G Tsc1 TSC complex subunit 1 multiple interactions ISO [Azacitidine affects the methylation of TSC1 promoter] which affects the expression of TSC1 mRNA CTD PMID:18538015 NCBI chr 3:32,367,434...32,416,565
Ensembl chr 3:32,367,670...32,416,568
JBrowse link
G Tsc2 TSC complex subunit 2 decreases methylation
multiple interactions
increases expression
ISO Azacitidine results in decreased methylation of TSC2 promoter
[Azacitidine affects the methylation of TSC2 promoter] which affects the expression of TSC2 mRNA
Azacitidine results in increased expression of TSC2 mRNA
CTD PMID:18538015 PMID:19250671 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO Azacitidine results in increased expression of TSHR mRNA CTD PMID:17679169 NCBI chr 6:116,072,321...116,206,009
Ensembl chr 6:116,072,281...116,206,010
JBrowse link
G Tspan32 tetraspanin 32 decreases expression ISO Azacitidine results in decreased expression of TSPAN32 mRNA CTD PMID:19194470 NCBI chr 1:207,619,566...207,633,885
Ensembl chr 1:207,619,567...207,656,946
JBrowse link
G Ttk Ttk protein kinase multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TTK mRNA CTD PMID:18720364 NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of UBE2C mRNA CTD PMID:18720364 NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678
JBrowse link
G Uhmk1 U2AF homology motif kinase 1 increases expression ISO Azacitidine results in increased expression of UHMK1 mRNA CTD PMID:20823114 NCBI chr13:84,929,418...84,949,194
Ensembl chr13:84,922,829...84,949,061
JBrowse link
G Ush2a usherin increases expression ISO Azacitidine results in increased expression of USH2A mRNA CTD PMID:20823114 NCBI chr13:102,368,783...103,035,230
Ensembl chr13:102,368,783...103,035,217
JBrowse link
G Ushbp1 USH1 protein network component harmonin binding protein 1 decreases expression ISO Azacitidine results in decreased expression of USHBP1 mRNA CTD PMID:20823114 NCBI chr16:18,091,311...18,101,927
Ensembl chr16:18,091,316...18,101,867
JBrowse link
G Vim vimentin decreases expression
increases expression
multiple interactions
EXP
ISO
Azacitidine results in decreased expression of VIM protein
Azacitidine results in increased expression of VIM mRNA; Azacitidine results in increased expression of VIM protein
[Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein
CTD PMID:17105402 PMID:20823114 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
JBrowse link
G Wdr47 WD repeat domain 47 decreases expression ISO Azacitidine results in decreased expression of WDR47 mRNA CTD PMID:19194470 NCBI chr 2:198,914,977...198,975,844
Ensembl chr 2:198,914,940...198,975,841
JBrowse link
G Wnt10b Wnt family member 10B increases expression EXP Azacitidine results in increased expression of WNT10B mRNA CTD PMID:27415467 NCBI chr 7:131,801,046...131,806,850
Ensembl chr 7:131,801,046...131,806,850
JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO Azacitidine results in increased expression of WNT5A mRNA CTD PMID:20823114 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860
JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 increases expression ISO Azacitidine results in increased expression of WWTR1 mRNA CTD PMID:20823114 NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950
JBrowse link
G Xaf1 XIAP associated factor 1 decreases expression
decreases methylation
increases expression
ISO Azacitidine results in decreased expression of XAF1 mRNA alternative form
Azacitidine results in decreased methylation of XAF1 promoter
Azacitidine results in increased expression of XAF1 mRNA; Azacitidine results in increased expression of XAF1 protein
CTD PMID:19077051 PMID:19549372 NCBI chr10:57,415,935...57,428,348
Ensembl chr10:57,415,658...57,428,349
JBrowse link
G Zfp189 zinc finger protein 189 decreases expression ISO Azacitidine results in decreased expression of ZNF189 mRNA CTD PMID:20823114 NCBI chr 5:68,668,225...68,679,606
Ensembl chr 5:68,668,244...68,679,812
JBrowse link
G Zfp64 zinc finger protein 64 affects methylation ISO Azacitidine affects the methylation of ZFP64 promoter CTD PMID:17546590 NCBI chr 3:178,085,604...178,114,557
Ensembl chr 3:178,085,605...178,114,557
JBrowse link
G Zp3 zona pellucida glycoprotein 3 increases expression ISO Azacitidine results in increased expression of ZP3 mRNA CTD PMID:20823114 NCBI chr12:26,327,161...26,334,126
Ensembl chr12:26,327,161...26,334,126
JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects binding ISO acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943
JBrowse link
acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases abundance
affects abundance
ISO ACLY protein results in increased abundance of Acetyl Coenzyme A
ACLY protein affects the abundance of Acetyl Coenzyme A
CTD PMID:28077572 PMID:36933457 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
JBrowse link
G App amyloid beta precursor protein affects localization
increases secretion
multiple interactions
ISO APP protein affects the localization of Acetyl Coenzyme A
Acetyl Coenzyme A results in increased secretion of APP protein modified form
Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
CTD PMID:16122837 PMID:22906069 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Crat carnitine O-acetyltransferase decreases activity EXP Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein CTD PMID:8075222 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions
ISO ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A
3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]
CTD PMID:25440059 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Acetyl Coenzyme A CTD PMID:33179799 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] CTD PMID:16122837 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Acetyl Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] CTD PMID:30213948 NCBI chr10:107,462,148...107,476,143
Ensembl chr10:107,462,109...107,476,135
JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
affects binding
ISO [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein]
Acetyl Coenzyme A binds to NAT1 protein
CTD PMID:20545351 PMID:22835378 NCBI chr16:26,984,882...27,005,194
Ensembl chr16:26,982,625...26,986,527
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
acryloyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl-CoA hydratase, short chain 1 increases abundance ISO ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886
JBrowse link
adenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase decreases metabolic processing
increases metabolic processing
ISO ADA alternative form results in decreased metabolism of Adenosine
ADA protein results in increased metabolism of Adenosine
CTD PMID:16221767 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions
affects binding
ISO
EXP
Adenosine analog binds to and affects the activity of ADORA1 protein; Adenosine analog binds to and results in decreased activity of ADORA1 protein; PD 81723 affects the reaction [Adenosine analog binds to and affects the activity of ADORA1 protein]; VUF 5455 affects the reaction [Adenosine analog binds to and affects the activity of ADORA1 protein]
[lead acetate results in increased expression of ADORA1 protein] which results in increased abundance of Adenosine; Adenosine analog binds to and results in increased activity of ADORA1 protein
Adenosine binds to ADORA1 protein
CTD PMID:10649980 PMID:11520205 PMID:18404447 PMID:20571079 PMID:20932874 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190
JBrowse link
G Adora2a adenosine A2a receptor multiple interactions
affects binding
ISO Adenosine analog binds to and results in decreased activity of ADORA2A protein; Adenosine promotes the reaction [Lipopolysaccharides results in increased expression of ADORA2A mRNA]
Adenosine binds to ADORA2A protein
CTD PMID:18404447 PMID:20067761 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
JBrowse link
G Adora2b adenosine A2B receptor affects response to substance ISO ADORA2B protein affects the susceptibility to Adenosine CTD PMID:16920807 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091
JBrowse link
G Adora3 adenosine A3 receptor multiple interactions
increases expression
affects binding
ISO Adenosine analog binds to and affects the activity of ADORA3 protein; Adenosine analog binds to and results in decreased activity of ADORA3 protein; Adenosine analog binds to and results in increased activity of ADORA3 protein; PD 81723 affects the reaction [Adenosine analog binds to and affects the activity of ADORA3 protein]; VUF 5455 affects the reaction [Adenosine analog binds to and affects the activity of ADORA3 protein]
Adenosine results in increased expression of ADORA3 mRNA
Adenosine binds to ADORA3 protein
CTD PMID:11520205 PMID:18404447 PMID:20067761 PMID:20571079 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO Adenosine inhibits the reaction [Methotrexate results in increased activity of ALPI protein] CTD PMID:16598758 NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780
JBrowse link
G Ampd2 adenosine monophosphate deaminase 2 multiple interactions ISO [tofacitinib results in decreased expression of AMPD2 protein] which affects the abundance of Adenosine CTD PMID:25496463 NCBI chr 2:198,395,767...198,408,514
Ensembl chr 2:198,395,768...198,408,796
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases localization
multiple interactions
ISO Adenosine results in increased localization of BAX protein
Thymidine inhibits the reaction [Adenosine results in increased localization of BAX protein]
CTD PMID:11570579 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
ISO Adenosine results in decreased expression of BCL2L1 mRNA; Adenosine results in decreased expression of BCL2L1 protein
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of BCL2L1 mRNA]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of BCL2L1 protein]
CTD PMID:20063052 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Adenosine results in decreased expression of BIRC2 mRNA; Adenosine results in decreased expression of BIRC2 protein CTD PMID:20063052 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Adenosine results in decreased expression of BIRC3 mRNA CTD PMID:20063052 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO Adenosine results in increased expression of BMP2 mRNA CTD PMID:34070360 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression
multiple interactions
ISO Adenosine results in increased expression of BMP4 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Adenosine results in increased expression of BMP4 mRNA]; PSB603 inhibits the reaction [Adenosine results in increased expression of BMP4 mRNA]; ZM 241385 inhibits the reaction [Adenosine results in increased expression of BMP4 mRNA]
CTD PMID:34070360 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A increases expression ISO Adenosine results in increased expression of BMPR1A mRNA CTD PMID:34070360 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP3 protein]; Thymidine inhibits the reaction [Adenosine results in increased activity of CASP3 protein] CTD PMID:11570579 PMID:16469385 PMID:17303086 PMID:20063052 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
ISO
EXP
Adenosine results in increased activity of CASP8 protein
Dipyridamole inhibits the reaction [Adenosine results in increased activity of CASP8 protein]
CTD PMID:16469385 PMID:17303086 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
ISO
EXP
Adenosine results in increased activity of CASP9 protein
Thymidine inhibits the reaction [Adenosine results in increased activity of CASP9 protein]
CTD PMID:11570579 PMID:16469385 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccnb1 cyclin B1 affects expression EXP Adenosine affects the expression of CCNB1 protein CTD PMID:19638569 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO
EXP
Adenosine results in increased expression of CCND1 mRNA
Adenosine results in increased expression of CCND1 protein
CTD PMID:19638569 PMID:34070360 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccne1 cyclin E1 increases expression EXP Adenosine results in increased expression of CCNE1 protein CTD PMID:19638569 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
JBrowse link
G Cd14 CD14 molecule increases expression ISO Adenosine results in increased expression of CD14 mRNA CTD PMID:21538184 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression
multiple interactions
ISO Adenosine results in decreased expression of CFLAR mRNA; Adenosine results in decreased expression of CFLAR mRNA alternative form; Adenosine results in decreased expression of CFLAR protein
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR mRNA alternative form]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR mRNA]; Dipyridamole inhibits the reaction [Adenosine results in decreased expression of CFLAR protein]
CTD PMID:17303086 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity
multiple interactions
ISO Adenosine results in increased activity of CFTR protein
[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein
CTD PMID:15039139 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression
multiple interactions
ISO Adenosine results in increased expression of CREB1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Adenosine results in increased expression of CREB1 mRNA]; PSB603 inhibits the reaction [Adenosine results in increased expression of CREB1 mRNA]; ZM 241385 inhibits the reaction [Adenosine results in increased expression of CREB1 mRNA]
CTD PMID:34070360 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO Adenosine results in increased expression of CTNNB1 mRNA CTD PMID:34070360 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
multiple interactions
ISO Adenosine results in increased expression of DIABLO mRNA; Adenosine results in increased expression of DIABLO protein
Dipyridamole inhibits the reaction [Adenosine results in increased expression of DIABLO mRNA]; Dipyridamole inhibits the reaction [Adenosine results in increased expression of DIABLO protein]
CTD PMID:20063052 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Adenosine results in increased expression of DKK1 mRNA CTD PMID:34070360 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression
multiple interactions
ISO Adenosine results in decreased expression of DPP4 mRNA; Adenosine results in decreased expression of DPP4 protein
[Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 protein; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 protein
CTD PMID:16611738 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G E2f1 E2F transcription factor 1 affects expression EXP Adenosine affects the expression of E2F1 protein CTD PMID:19638569 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
JBrowse link
G E2f3 E2F transcription factor 3 affects expression EXP Adenosine affects the expression of E2F3 protein CTD PMID:19638569 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
JBrowse link
G Egf epidermal growth factor increases expression
multiple interactions
ISO Adenosine results in increased expression of EGF mRNA
Adenosine results in increased expression of and results in increased secretion of EGF protein
CTD PMID:34070360 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Adenosine results in increased expression of ESR1 protein CTD PMID:29360751 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 increases expression ISO Adenosine results in increased expression of ESR2 protein CTD PMID:29360751 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fadd Fas associated via death domain decreases expression
multiple interactions
ISO Adenosine results in decreased expression of FADD mRNA
Dipyridamole inhibits the reaction [Adenosine results in decreased expression of FADD mRNA]
CTD PMID:17303086 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976
JBrowse link
G Faslg Fas ligand increases expression
multiple interactions
ISO Adenosine results in increased expression of FASLG protein
[Adenosine co-treated with Coformycin] results in decreased expression of FASL mRNA
CTD PMID:11992407 PMID:16419169 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G Fgf6 fibroblast growth factor 6 multiple interactions ISO Adenosine results in increased expression of and results in increased secretion of FGF6 protein CTD PMID:34070360 NCBI chr 4:161,541,089...161,549,624
Ensembl chr 4:161,541,089...161,553,521
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression ISO Adenosine results in increased expression of FSHB protein CTD PMID:29360751 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
JBrowse link
G Fzd3 frizzled class receptor 3 increases expression ISO Adenosine results in increased expression of FZD3 mRNA CTD PMID:34070360 NCBI chr15:43,596,962...43,664,047
Ensembl chr15:43,596,965...43,663,960
JBrowse link
G Fzd5 frizzled class receptor 5 increases expression ISO Adenosine results in increased expression of FZD5 mRNA CTD PMID:34070360 NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases secretion ISO Adenosine results in increased secretion of GDNF protein CTD PMID:34070360 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
increases expression
ISO Adenosine results in increased phosphorylation of GSK3B protein
Adenosine results in increased expression of GSK3B mRNA
CTD PMID:34070360 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
JBrowse link
G Gzmb granzyme B multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of GZMB mRNA CTD PMID:11992407 NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hgf hepatocyte growth factor affects expression EXP Adenosine affects the expression of HGF protein CTD PMID:19638569 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Adenosine results in increased expression of HIF1A mRNA CTD PMID:20067761 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of Adenosine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine]
CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of IFNG protein CTD PMID:11992407 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
multiple interactions
ISO Adenosine affects the expression of IGF1 mRNA
Adenosine results in increased expression of and results in increased secretion of IGF1 protein
CTD PMID:34070360 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions ISO Adenosine results in increased expression of and results in increased secretion of IGF2 protein CTD PMID:34070360 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
ISO Adenosine promotes the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]
Adenosine results in increased expression of IL10 mRNA; Adenosine results in increased expression of IL10 protein
CTD PMID:11023991 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il12b interleukin 12B decreases expression
multiple interactions
ISO Adenosine results in decreased expression of IL12B protein
Adenosine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]
CTD PMID:11023991 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Adenosine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein] CTD PMID:24878381 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions EXP Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1] CTD PMID:24878381 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of IL2 protein CTD PMID:11992407 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression ISO Adenosine results in increased expression of LEF1 mRNA CTD PMID:34070360 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929
JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO Adenosine results in increased expression of LY96 mRNA CTD PMID:21538184 NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:7,365,557...7,395,816
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO Adenosine results in increased phosphorylation of MAP2K1 protein CTD PMID:34070360 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases phosphorylation ISO Adenosine results in increased phosphorylation of MAP2K2 protein CTD PMID:34070360 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of DPP4 protein CTD PMID:16611738 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO Adenosine results in decreased phosphorylation of MAPK3 protein
[Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 mRNA; [Adenosine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of DPP4 protein
CTD PMID:16611738 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression EXP Adenosine results in increased expression of MET protein CTD PMID:19638569 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
JBrowse link
G Mki67 marker of proliferation Ki-67 affects expression
increases expression
ISO
EXP
Adenosine affects the expression of MKI67 mRNA
Adenosine results in increased expression of MKI67 protein
CTD PMID:19638569 PMID:34070360 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Adenosine results in increased phosphorylation of MTOR protein CTD PMID:34070360 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression
multiple interactions
ISO
EXP
Adenosine results in decreased expression of MYC protein
Adenosine results in increased expression of MYC protein
Adenosine results in increased expression of MYC mRNA
Thymidine inhibits the reaction [Adenosine results in decreased expression of MYC protein]; Uridine inhibits the reaction [Adenosine results in decreased expression of MYC protein]
CTD PMID:9808420 PMID:19638569 PMID:34070360 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Adenosine co-treated with Homocysteine] results in decreased expression of NFKBIA mRNA CTD PMID:24224954 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nos2 nitric oxide synthase 2 decreases stability
multiple interactions
EXP Adenosine results in decreased stability of NOS2 mRNA
Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Adenosine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]
CTD PMID:24878381 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [alpha,beta-methyleneadenosine 5'-diphosphate results in decreased activity of NT5E protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine] CTD PMID:23437309 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Adenosine results in increased expression of PCNA protein CTD PMID:19638569 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pgf placental growth factor increases secretion ISO Adenosine results in increased secretion of PGF protein CTD PMID:34070360 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Adenosine results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Prf1 perforin 1 multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of PRF1 mRNA CTD PMID:11992407 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,788,972...29,795,124
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased metabolism of Adenosine; [Prostaglandin D2 results in increased activity of PTGDR protein] which results in increased secretion of Adenosine CTD PMID:11562489 NCBI chr15:19,790,499...19,797,873
Ensembl chr15:19,790,499...19,797,873
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein] CTD PMID:24224954 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Ren renin decreases secretion EXP Adenosine results in decreased secretion of REN protein CTD PMID:3044993 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [Adenosine co-treated with Homocysteine co-treated with TNF protein] results in increased cleavage of RIPK1 protein CTD PMID:24224954 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 increases phosphorylation ISO Adenosine results in increased phosphorylation of RPS6KB1 protein CTD PMID:34070360 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
JBrowse link
G Slc28a1 solute carrier family 28 member 1 affects transport
multiple interactions
ISO SLC28A1 protein affects the transport of Adenosine
Adenosine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]
CTD PMID:9124315 NCBI chr 1:144,490,453...144,532,025
Ensembl chr 1:144,490,623...144,531,544
JBrowse link
G Slc28a2 solute carrier family 28 member 2 increases transport ISO SLC28A2 protein results in increased transport of Adenosine CTD PMID:10087507 NCBI chr 3:129,778,425...129,841,292
Ensembl chr 3:129,807,537...129,841,291
JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions
increases uptake
affects abundance
ISO
EXP
4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; [4-nitrobenzylthioinosine results in decreased activity of SLC29A1 protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine]; [SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine; Dipyridamole inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole promotes the reaction [[SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine]
SLC29A1 protein alternative form results in increased uptake of Adenosine; SLC29A1 protein results in increased uptake of Adenosine
cilostazol inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; draflazine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ticagrelor inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]
Adenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine]
SLC29A1 affects the abundance of Adenosine
CTD PMID:9353301 PMID:9396714 PMID:11179696 PMID:21283641 PMID:21872611 More... NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
JBrowse link
G Slc29a2 solute carrier family 29 member 2 increases uptake ISO SLC29A2 protein results in increased uptake of Adenosine CTD PMID:9396714 NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:211,757,000...211,764,560
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Adenosine CTD PMID:19164483 NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299
JBrowse link
G Slc5a5 solute carrier family 5 member 5 increases expression EXP Adenosine results in increased expression of SLC5A5 mRNA; Adenosine results in increased expression of SLC5A5 protein CTD PMID:16954431 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691
JBrowse link
G Tgfa transforming growth factor alpha increases secretion ISO Adenosine results in increased secretion of TGFA protein CTD PMID:34070360 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Adenosine results in increased expression of TGFB1 mRNA; Adenosine results in increased expression of TGFB1 protein CTD PMID:34070360 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression
multiple interactions
ISO Adenosine results in increased expression of TGFB2 mRNA
Adenosine results in increased expression of and results in increased secretion of TGFB2 protein
CTD PMID:34070360 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856
JBrowse link
G Tlr4 toll-like receptor 4 increases expression
affects localization
multiple interactions
ISO Adenosine results in increased expression of TLR4 mRNA
Adenosine affects the localization of TLR4 protein
Adenosine promotes the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of TLR4 protein]
CTD PMID:21538184 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; [Adenosine co-treated with Homocysteine co-treated with TNF protein] results in increased cleavage of RIPK1 protein; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein affects the localization of RELA protein modified form]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; [Adenosine co-treated with Homocysteine] affects the reaction [TNF protein results in increased phosphorylation of RELA protein]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; [Adenosine co-treated with Homocysteine] results in increased susceptibility to TNF protein; Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; ZM 241385 inhibits the reaction [Adenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]
Adenosine results in decreased expression of TNF protein
CTD PMID:11023991 PMID:21538184 PMID:24224954 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 mRNA]; [Adenosine co-treated with Homocysteine] inhibits the reaction [TNF protein results in increased expression of TNFAIP3 protein]; [Adenosine co-treated with Homocysteine] results in decreased expression of TNFAIP3 mRNA; [Adenosine co-treated with Homocysteine] results in decreased expression of TNFAIP3 protein CTD PMID:24224954 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Adenosine co-treated with Coformycin] results in decreased expression of TNFSF10 mRNA CTD PMID:11992407 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
JBrowse link
G Upp1 uridine phosphorylase 1 increases metabolic processing ISO UPP1 protein results in increased metabolism of Adenosine CTD PMID:15772079 NCBI chr14:88,023,155...88,043,036
Ensembl chr14:88,023,351...88,043,034
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
increases secretion
ISO Adenosine promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein]; Adenosine results in increased expression of and results in increased secretion of VEGFA protein
Adenosine results in increased expression of VEGFA mRNA
Adenosine results in increased secretion of VEGFA protein
CTD PMID:20067761 PMID:34070360 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
adenosine 3',5'-bismonophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions EXP Glutathione Disulfide affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]; Glutathione Disulfide affects the reaction [Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein]]; Polychlorinated Biphenyls analog affects the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT1A1 protein] CTD PMID:21130751 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions ISO [2,2',4,4'-tetrabromodiphenyl ether metabolite co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; [tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein; Estradiol inhibits the reaction [[tetrabromobisphenol A co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein]; tetrabromobisphenol A inhibits the reaction [[Estradiol co-treated with adenosine 3'-phosphate-5'-phosphate] binds to SULT1E1 protein] CTD PMID:23959441 NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding
multiple interactions
ISO adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein
Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]; Dehydroepiandrosterone inhibits the reaction [Benzoquinones analog inhibits the reaction [adenosine 3'-phosphate-5'-phosphate binds to SULT2A1 protein]]
CTD PMID:24059442 NCBI chr 1:84,582,011...84,639,001 JBrowse link
adenosine 5'-(hexahydrogen pentaphosphate) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt11 nudix hydrolase 11 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate CTD PMID:12121577 NCBI chr  X:18,998,587...19,005,208
Ensembl chr  X:18,998,461...19,005,208
JBrowse link
adenosine 5'-[gamma-thio]triphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd80 Cd80 molecule increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD80 protein CTD PMID:15944274 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
JBrowse link
G Cd86 CD86 molecule increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of CD86 protein CTD PMID:15944274 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
JBrowse link
G Il10 interleukin 10 decreases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in decreased expression of IL10 protein CTD PMID:15944274 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il12b interleukin 12B increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL12B protein CTD PMID:15944274 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Il1b interleukin 1 beta increases expression ISO adenosine 5'-O-(3-thiotriphosphate) results in increased expression of IL1B protein CTD PMID:15944274 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G P2rx7 purinergic receptor P2X 7 affects response to substance ISO P2RX7 protein affects the susceptibility to adenosine 5'-O-(3-thiotriphosphate) CTD PMID:12873706 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO adenosine 5'-O-(3-thiotriphosphate) inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:19,790,499...19,797,873
Ensembl chr15:19,790,499...19,797,873
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions
EXP adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein
Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]
CTD PMID:11140687 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021
JBrowse link
adenosine 5'-monophosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [4-dimethylaminocinnamaldehyde co-treated with Adenosine Monophosphate] binds to ALDH1A1 protein CTD PMID:10609638 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases abundance ISO ERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate CTD PMID:25440059 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]] CTD PMID:11390963 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169
JBrowse link
G Nudt11 nudix hydrolase 11 multiple interactions ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:18,998,587...19,005,208
Ensembl chr  X:18,998,461...19,005,208
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Adenosine Monophosphate results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine Monophosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
JBrowse link
G Tp73 tumor protein p73 affects abundance ISO TP73 protein affects the abundance of Adenosine Monophosphate CTD PMID:25554796 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552
JBrowse link
ADP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects binding
ISO estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; Vanadates promotes the reaction [Adenosine Diphosphate binds to ABCC1 protein]
Adenosine Diphosphate binds to ABCC1 protein; Adenosine Diphosphate binds to ABCC1 protein mutant form
CTD PMID:18336795 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP Adenosine Diphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Ak1 adenylate kinase 1 increases abundance ISO AK1 protein results in increased abundance of Adenosine Diphosphate CTD PMID:11390963 NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757
JBrowse link
G Alb albumin decreases secretion
multiple interactions
ISO Adenosine Diphosphate results in decreased secretion of ALB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein]
CTD PMID:17303692 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases abundance
ISO PF-06840003 inhibits the reaction [APP protein mutant form results in increased abundance of Adenosine Diphosphate]
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate]
CTD PMID:39172838 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Axl Axl receptor tyrosine kinase decreases response to substance ISO AXL protein results in decreased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009
JBrowse link
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein] CTD PMID:16781456 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cd40lg CD40 ligand increases expression
multiple interactions
ISO Adenosine Diphosphate results in increased expression of CD40LG protein
clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein]
CTD PMID:11297035 PMID:17043144 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Adenosine Diphosphate binds to and results in decreased activity of CFTR protein; P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] CTD PMID:15684079 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Diphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein] CTD PMID:23184943 NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid] CTD PMID:16772608 PMID:18004210 PMID:18394438 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Dtymk deoxythymidylate kinase multiple interactions ISO DTYMK protein binds to [N1-(4-bis(pivaloyloxymethyl)phosphinylbuten-2-yl)thymine co-treated with Adenosine Diphosphate] CTD PMID:21128666 NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]] CTD PMID:32941855 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]] CTD PMID:32941855 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
JBrowse link
G Epha4 Eph receptor A4 increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein
Benzoic Acid analog inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein]
CTD PMID:22273509 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:86,263,982...86,406,755
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
decreases activity
ISO Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein]
Adenosine Diphosphate results in decreased activity of ERN1 protein
CTD PMID:25164867 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
JBrowse link
G F2 coagulation factor II, thrombin increases abundance
multiple interactions
ISO F2 protein results in increased abundance of Adenosine Diphosphate
Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]
CTD PMID:15342215 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
JBrowse link
G Fga fibrinogen alpha chain multiple interactions
increases secretion
ISO Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein] CTD PMID:17303692 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577
JBrowse link
G Fgb fibrinogen beta chain decreases secretion
multiple interactions
ISO Adenosine Diphosphate results in decreased secretion of FGB protein
Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein]
CTD PMID:17303692 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434
JBrowse link
G Fgg fibrinogen gamma chain increases secretion
multiple interactions
ISO Adenosine Diphosphate results in increased secretion of FGG protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein]
CTD PMID:17303692 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Gas6 growth arrest specific 6 increases response to substance ISO GAS6 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of HRAS protein CTD PMID:16388579 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate] CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Adenosine Diphosphate results in increased expression of IL6 protein
MRS 2211 inhibits the reaction [Adenosine Diphosphate results in increased expression of IL6 protein]
CTD PMID:24849676 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate] CTD PMID:16214444 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833
JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 multiple interactions ISO Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr  X:70,612,118...70,617,158
Ensembl chr  X:70,612,521...70,617,158
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of MAPK1 protein
Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]]
CTD PMID:15034929 PMID:32941855 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of MAPK3 protein
Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]]
CTD PMID:15034929 PMID:32941855 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK9 protein] CTD PMID:24466103 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
increases abundance
ISO PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Adenosine Diphosphate] CTD PMID:39172838 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase increases response to substance ISO MERTK protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate] CTD PMID:11498454 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nt5e 5' nucleotidase, ecto decreases activity ISO Adenosine Diphosphate analog results in decreased activity of NT5E protein CTD PMID:18404487 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
JBrowse link
G P2ry12 purinergic receptor P2Y12 affects response to substance
increases response to substance
multiple interactions
ISO
EXP
P2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate; P2RY12 protein affects the susceptibility to Adenosine Diphosphate
P2RY12 protein results in increased susceptibility to Adenosine Diphosphate
Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate]
P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]
CTD PMID:11196645 PMID:11413167 PMID:18404433 PMID:23849096 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:145,629,967...145,633,410
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases secretion
multiple interactions
ISO Adenosine Diphosphate results in increased secretion of PDGFB protein
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein]
CTD PMID:17303692 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
JBrowse link
G Pf4 platelet factor 4 increases secretion
multiple interactions
ISO Adenosine Diphosphate results in increased secretion of PF4 protein
silidianin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; Silybin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; silychristin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]
CTD PMID:19428933 PMID:29439388 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO Adenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248
JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Adenosine Diphosphate CTD PMID:24338473 NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408
JBrowse link
G Ppbp pro-platelet basic protein increases secretion ISO Adenosine Diphosphate results in increased secretion of PPBP protein CTD PMID:19428933 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Adenosine Diphosphate binds to and affects the folding of PPP5C protein CTD PMID:23184943 NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate] CTD PMID:39172838 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 increases glutathionylation
multiple interactions
EXP Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein
CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein]
CTD PMID:16781456 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416
JBrowse link
G Selp selectin P multiple interactions
increases expression
ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]; P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein] CTD PMID:9740346 PMID:18394438 PMID:18404433 PMID:23249183 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987
JBrowse link
G Sirt3 sirtuin 3 decreases abundance ISO SIRT3 protein results in decreased abundance of Adenosine Diphosphate CTD PMID:23166782 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Taldo1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of Adenosine Diphosphate CTD PMID:19436114 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535
JBrowse link
G Thbs1 thrombospondin 1 increases secretion ISO Adenosine Diphosphate results in increased secretion of THBS1 protein CTD PMID:17303692 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase increases response to substance ISO TYRO3 protein results in increased susceptibility to Adenosine Diphosphate CTD PMID:15733062 NCBI chr 3:127,231,468...127,254,806
Ensembl chr 3:127,231,903...127,250,943
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation
multiple interactions
ISO Adenosine Diphosphate results in increased phosphorylation of VASP protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of VASP protein]
CTD PMID:25329809 NCBI chr 1:88,038,026...88,053,783
Ensembl chr 1:88,038,037...88,058,650
JBrowse link
ADP-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adprh ADP-ribosylarginine hydrolase increases hydrolysis ISO ADPRH protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite CTD PMID:21498885 NCBI chr11:75,805,347...75,811,686
Ensembl chr11:75,805,310...75,812,452
JBrowse link
G Adprs ADP-ribosylserine hydrolase increases hydrolysis
multiple interactions
ISO ADPRS protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite
Adenosine Diphosphate Ribose inhibits the reaction [ADPRS protein results in increased hydrolysis of O-Acetyl-ADP-Ribose]
CTD PMID:21498885 NCBI chr 5:143,898,542...143,903,816
Ensembl chr 5:143,898,542...143,903,816
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions ISO NOS1 protein affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased ribosylation of Adenosine Diphosphate Ribose] CTD PMID:10318960 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions
increases activity
EXP
ISO
Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]
Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]]; Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Copper Sulfate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; ferrous chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Miconazole inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Selenium Oxides inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]
4-amylcinnamoylanthranilic acid inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; [Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein; Glutathione inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; Glutathione inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium]
CTD PMID:18204483 PMID:20878536 PMID:21900507 PMID:22750002 PMID:33309544 More... NCBI chr20:10,703,190...10,752,795
Ensembl chr20:10,704,482...10,752,802
JBrowse link
aldehydo-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
ISO [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]
Ribose results in increased expression of AGER protein
CTD PMID:30101366 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
JBrowse link
G B2m beta-2 microglobulin increases glycation ISO Ribose results in increased glycation of B2M protein CTD PMID:21864514 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Creatine co-treated with Ribose] results in decreased activity of CASP3 protein CTD PMID:21220914 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation ISO Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation ISO Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
JBrowse link
G Ins1 insulin 1 increases secretion ISO Ribose results in increased secretion of INS1 protein CTD PMID:30101366 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation
ISO [Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein
Ribose results in increased phosphorylation of NFKBIA protein
CTD PMID:30101366 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
multiple interactions
ISO Ribose results in increased phosphorylation of RELA protein
[Ribose co-treated with Glucose] affects the localization of RELA protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]; Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]
CTD PMID:30101366 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
AMP-PNP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP Adenylyl Imidodiphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Cftr CF transmembrane conductance regulator affects activity ISO Adenylyl Imidodiphosphate affects the activity of CFTR protein CTD PMID:15657297 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 affects binding ISO Adenylyl Imidodiphosphate binds to CSNK2A1 protein CTD PMID:34344863 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698
JBrowse link
G Ptgdr prostaglandin D2 receptor multiple interactions ISO Adenylyl Imidodiphosphate inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 NCBI chr15:19,790,499...19,797,873
Ensembl chr15:19,790,499...19,797,873
JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO Adenosine Triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr10:95,416,984...95,490,647
Ensembl chr10:95,416,205...95,490,452
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO
EXP
Adenosine Triphosphate promotes the reaction [ABCB11 protein results in increased uptake of fexofenadine] CTD PMID:18245269 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects binding
increases hydrolysis
ISO
EXP
[Cobalt results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Magnesium results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; [Manganese results in increased activity of ABCB1 protein] which results in increased hydrolysis of Adenosine Triphosphate; ABCB1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; aurapten promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; crizotinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; lapatinib promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate
CTD PMID:2900677 PMID:14978246 PMID:18829547 PMID:18955043 PMID:22233293 More... NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects activity
increases hydrolysis
affects binding
ISO [Adenosine Triphosphate affects the activity of ABCC1 protein] which results in increased transport of Acetaminophen metabolite; ABCC1 protein binds to and results in increased degradation of Adenosine Triphosphate; ABCC1 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; ABCC1 protein mutant form binds to and results in increased hydrolysis of Adenosine Triphosphate; Adenosine Triphosphate binds to and affects the folding of ABCC1 protein; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Bilirubin]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of estradiol-17 beta-glucuronide]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of Leukotriene C4]; daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; nobiletin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Resveratrol promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Daunorubicin promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Vanadates inhibits the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]
Adenosine Triphosphate binds to ABCC1 protein
CTD PMID:10856430 PMID:11278000 PMID:14978246 PMID:15245331 PMID:15355964 More... NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
affects activity
affects metabolic processing
EXP
ISO
Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3]; Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]
Adenosine Triphosphate affects the activity of ABCC2 protein
[Adenosine Triphosphate affects the activity of ABCC2 protein] which results in increased transport of Acetaminophen metabolite; [Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; Adenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]; verlukast inhibits the reaction [[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide]
ABCC2 protein affects the metabolism of Adenosine Triphosphate
Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]
CTD PMID:9067317 PMID:9794919 PMID:20060011 PMID:22027652 PMID:24039982 More... NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Adenosine Triphosphate promotes the reaction [ABCC3 protein affects the transport of fexofenadine] CTD PMID:18245269 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
affects activity
increases hydrolysis
ISO [Adenosine Triphosphate affects the activity of ABCC4 protein] which results in increased transport of Acetaminophen metabolite; ABCC4 protein binds to and results in increased hydrolysis of Adenosine Triphosphate; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; hesperetin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; naringenin promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin affects the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Quercetin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]]; Resveratrol promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]; Silymarin inhibits the reaction [Alprostadil promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:14978246 PMID:16156793 PMID:32472168 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects binding ISO Adenosine Triphosphate binds to ABCC6 protein CTD PMID:11880368 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions EXP Adenosine Triphosphate deficiency inhibits the reaction [Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein]] CTD PMID:19095654 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 multiple interactions EXP
ISO
Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]
Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]
CTD PMID:11390963 PMID:28842488 NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases hydrolysis
multiple interactions
ISO ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate; Lapatinib promotes the reaction [ABCG2 protein results in increased hydrolysis of Adenosine Triphosphate]; Sulfasalazine inhibits the reaction [[Adenosine Triphosphate co-treated with ABCG2 protein] results in increased uptake of estrone sulfate]
CTD PMID:18829547 PMID:32003934 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions
increases chemical synthesis
ISO [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein]
ABL1 protein mutant form results in increased chemical synthesis of Adenosine Triphosphate
CTD PMID:19366808 PMID:33070465 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 multiple interactions ISO [ACSL5 protein affects the susceptibility to Palmitic Acid] which affects the abundance of Adenosine Triphosphate CTD PMID:32347412 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ACTA2 mRNA]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ACTA2 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 mRNA]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of ACTA2 protein] CTD PMID:32721574 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases secretion EXP ADCYAP1 protein results in increased secretion of Adenosine Triphosphate CTD PMID:18563302 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
decreases expression
EXP Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein]; CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein]; Cyclosporine inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A protein] CTD PMID:21464294 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP Adenosine Triphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:1848756 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases activity
multiple interactions
ISO Adenosine Triphosphate results in decreased activity of AKT1 protein
Alcohols inhibits the reaction [Adenosine Triphosphate results in decreased activity of AKT1 protein]
CTD PMID:24300283 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases abundance ISO ALDH5A1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29031482 NCBI chr17:40,560,373...40,586,711
Ensembl chr17:40,558,347...40,586,714
JBrowse link
G Alk ALK receptor tyrosine kinase affects binding
multiple interactions
ISO ALK protein binds to Adenosine Triphosphate
[ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]] which results in decreased susceptibility to crizotinib; ALK protein mutant form promotes the reaction [ALK protein binds to Adenosine Triphosphate]
CTD PMID:22072639 NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases response to substance
multiple interactions
ISO ALPL gene mutant form results in increased susceptibility to Adenosine Triphosphate
ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
CTD PMID:27466191 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Anxa1 annexin A1 multiple interactions EXP [Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein; arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]; Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein] CTD PMID:20655937 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases secretion
ISO Adenosine Triphosphate inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]; Adenosine Triphosphate inhibits the reaction [Rotenone results in decreased secretion of APP protein modified form]; Rotenone inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Adenosine Triphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Adenosine Triphosphate]
CTD PMID:22906069 PMID:39172838 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions EXP Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; ARRB2 protein affects the reaction [Adenosine Triphosphate results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487
JBrowse link
G Asic1 acid sensing ion channel subunit 1 multiple interactions EXP [Acids binds to and affects the activity of ASIC1 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr 7:132,677,158...132,707,379
Ensembl chr 7:132,698,723...132,707,832
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions EXP [Acids binds to and affects the activity of ASIC2 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr10:66,368,308...67,438,237
Ensembl chr10:66,368,310...66,636,245
JBrowse link
G Asic3 acid sensing ion channel subunit 3 multiple interactions EXP [Acids binds to and affects the activity of ASIC3 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:11,652,946...11,657,367
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions ISO [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7A protein CTD PMID:20964302 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:75,159,782...75,267,093
JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions
increases phosphorylation
ISO [Copper co-treated with Adenosine Triphosphate] results in increased phosphorylation of ATP7B protein
Adenosine Triphosphate results in increased phosphorylation of ATP7B protein
CTD PMID:19405516 PMID:20964302 NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases hydrolysis EXP ATP8B1 protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:11584374 NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027
JBrowse link
G Avp arginine vasopressin multiple interactions
increases secretion
EXP Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein]; bisindolylmaleimide I inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Adenosine Triphosphate binds to P2RY11 protein] which results in decreased expression of BCL2 protein CTD PMID:21503959 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase multiple interactions ISO [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases abundance ISO BIRC5 protein results in increased abundance of Adenosine Triphosphate CTD PMID:32497533 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Cabin1 calcineurin binding protein 1 multiple interactions EXP CABIN1 protein inhibits the reaction [Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein] CTD PMID:21464294 NCBI chr20:12,892,750...13,014,801
Ensembl chr20:12,892,771...13,014,800
JBrowse link
G Calca calcitonin-related polypeptide alpha increases secretion
multiple interactions
EXP Adenosine Triphosphate results in increased secretion of CALCA protein
Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]; Flurbiprofen inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]; Suramin inhibits the reaction [Adenosine Triphosphate promotes the reaction [Protons results in increased secretion of CALCA protein]]
CTD PMID:12044622 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529
JBrowse link
G Casp1 caspase 1 increases activity
multiple interactions
EXP
ISO
Adenosine Triphosphate results in increased activity of CASP1 mRNA; Adenosine Triphosphate results in increased activity of CASP1 protein
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]
[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of and results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; dapansutrile inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; fraxinellone inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of and results in increased cleavage of CASP1 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of CASP1 protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form]; neoisoliquiritin affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP1 protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of CASP1 protein modified form; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased activity of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of CASP1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein; [Niclosamide co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASP1 protein; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of CASP1 protein]; dapansutrile inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of CASP1 protein modified form]; Ibuprofen inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; leojaponin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased activity of CASP1 protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein modified form]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; prim-O-glucosylcimifugin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA]; tabersonine inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]
CTD PMID:18604214 PMID:19130485 PMID:21832250 PMID:23430110 PMID:24149798 More... NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO Adenosine Triphosphate results in increased expression of CASP3
Adenosine Triphosphate inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of CASP3]
CTD PMID:19448140 PMID:24732427 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp4 caspase 4 multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of CASP4 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased secretion of and results in increased activity of CASP4 protein]
Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein]
CTD PMID:24149798 PMID:25288807 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
JBrowse link
G Cat catalase increases expression ISO Adenosine Triphosphate results in increased expression of CAT mRNA CTD PMID:22129738 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion
multiple interactions
ISO Adenosine Triphosphate results in increased secretion of CCL3 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CCL3 protein]
CTD PMID:26522449 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]; [Phosphatidylinositol 4,5-Diphosphate co-treated with Adenosine Triphosphate] results in increased activity of CFTR protein; Adenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]; Adenosine Triphosphate binds to and results in increased activity of CFTR protein; Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides] CTD PMID:14710196 PMID:15623556 PMID:17178710 PMID:20675434 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions ISO Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]
Adenosine Triphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]
CTD PMID:23184943 NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein]; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA; [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; Adenosine Triphosphate promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of COL1A1 mRNA]; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of COL1A1 protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 mRNA]; L 709049 inhibits the reaction [[[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of Biological Factors] which results in increased expression of COL1A1 protein] CTD PMID:32721574 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:14975680 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions ISO [Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate; Carnitine promotes the reaction [[Bezafibrate results in increased activity of CPT2 protein] which results in increased abundance of Adenosine Triphosphate] CTD PMID:21816645 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein multiple interactions ISO [ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; [BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein; sorafenib inhibits the reaction [[ABL1 protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein]; sorafenib inhibits the reaction [[BCR protein mutant form co-treated with Adenosine Triphosphate] results in increased phosphorylation of CRKL protein] CTD PMID:19366808 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [CSF2 protein affects the susceptibility to stearic acid] which affects the abundance of Adenosine Triphosphate CTD PMID:32347412 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 multiple interactions
affects binding
ISO silmitasertib inhibits the reaction [Adenosine Triphosphate binds to [CSNK2A1 protein binds to CSNK2A1 protein binds to CSNK2B protein binds to CSNK2B protein]] CTD PMID:21174434 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698
JBrowse link
G Csnk2b casein kinase 2 beta multiple interactions
affects binding
ISO silmitasertib inhibits the reaction [Adenosine Triphosphate binds to [CSNK2A1 protein binds to CSNK2A1 protein binds to CSNK2B protein binds to CSNK2B protein]] CTD PMID:21174434 NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
JBrowse link
G Cstb cystatin B multiple interactions ISO Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP1 protein]; Adenosine Triphosphate promotes the reaction [[CSTB gene mutant form results in increased susceptibility to lipopolysaccharide, E coli O55-B5] which results in increased cleavage of CASP4 protein] CTD PMID:25288807 NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199
JBrowse link
G Ctsb cathepsin B increases activity
multiple interactions
ISO Adenosine Triphosphate results in increased activity of CTSB protein
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of CTSB protein]
CTD PMID:26522449 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases secretion
multiple interactions
ISO Adenosine Triphosphate results in increased secretion of CXCL2 protein
azetidine inhibits the reaction [Adenosine Triphosphate results in increased secretion of CXCL2 protein]
CTD PMID:26522449 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
JBrowse link
G Dmd dystrophin increases secretion
multiple interactions
ISO DMD gene mutant form results in increased secretion of Adenosine Triphosphate
Nifedipine inhibits the reaction [DMD gene mutant form results in increased secretion of Adenosine Triphosphate]
CTD PMID:24349043 NCBI chr  X:51,070,098...53,437,845
Ensembl chr  X:51,070,273...53,437,835
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]] CTD PMID:32941855 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]] CTD PMID:32941855 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
ISO sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of EGFR protein] CTD PMID:26104857 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression
EXP Iodoacetates inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]; Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of EGR1 mRNA] CTD PMID:10723097 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO Adenosine Triphosphate promotes the reaction [Toluene 2,4-Diisocyanate results in increased expression of ENPP2 protein] CTD PMID:26072274 NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 decreases activity ISO Adenosine Triphosphate results in decreased activity of ENPP7 protein CTD PMID:12885774 NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,740,763...104,745,760
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions
ISO ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate
nicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate]
CTD PMID:25440059 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions
increases transport
increases abundance
increases secretion
ISO 2,4,3',5'-tetramethoxystilbene inhibits the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; [RWJ-56110 co-treated with 2,4,3',5'-tetramethoxystilbene] inhibits the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; calmidazolium affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; Fendiline affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]; Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]; Resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]
F2 protein results in increased transport of Adenosine Triphosphate
STXBP2 protein affects the reaction [F2 protein results in increased transport of Adenosine Triphosphate]
CTD PMID:2030746 PMID:15342215 PMID:30696774 PMID:35288162 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246
JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases abundance
ISO FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]; Protein Kinase Inhibitors inhibits the reaction [FASN protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:26670611 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
JBrowse link
G Fbp1 fructose-bisphosphatase 1 multiple interactions ISO [Enzyme Inhibitors results in decreased activity of FBP1 protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:31974165 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
JBrowse link
G Fbxo3 F-box protein 3 multiple interactions EXP FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein] CTD PMID:35962723 NCBI chr 3:110,872,185...110,904,479
Ensembl chr 3:110,872,220...110,904,479
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Adenosine Triphosphate results in increased expression of FOS mRNA
ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
[Phenylephrine co-treated with Adenosine Triphosphate] results in increased expression of FOS mRNA; Glucose affects the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Iodoacetates inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Potassium Cyanide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA]
CTD PMID:10723097 PMID:19463813 PMID:27466191 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression
multiple interactions
ISO Adenosine Triphosphate results in increased expression of FSCN1 mRNA
Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of FSCN1 mRNA]
CTD PMID:29733962 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions ISO Adenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] CTD PMID:15788719 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
JBrowse link
G Gh1 growth hormone 1 multiple interactions
increases secretion
ISO
EXP
oxophenylarsine inhibits the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; Phosphatidylinositol 4,5-Diphosphate affects the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]
NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; oxophenylarsine inhibits the reaction [NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]]
CTD PMID:12471042 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
JBrowse link
G Gja1 gap junction protein, alpha 1 increases export ISO GJA1 protein mutant form results in increased export of Adenosine Triphosphate; GJA1 protein results in increased export of Adenosine Triphosphate CTD PMID:17687502 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
JBrowse link
G Gsdmd gasdermin D multiple interactions ISO
EXP
[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of GSDMD protein; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of GSDMD protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein]
CTD PMID:33851234 PMID:34212273 PMID:34217685 PMID:35962723 PMID:36577999 More... NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO [GSTP1 protein co-treated with Glutathione] inhibits the reaction [[Adenosine Triphosphate results in increased metabolism of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-amino-1-methyl-6-phenolimidazo(4,5-b)pyridine-DNA adduct]; [GSTP1 protein co-treated with Glutathione] inhibits the reaction [Adenosine Triphosphate results in increased activity of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine] CTD PMID:11196146 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions
affects binding
ISO [Curcumin binds to 4-bis(2-chloroethyl)aminobenzaldehyde] inhibits the reaction [HCK protein binds to Adenosine Triphosphate] CTD PMID:33617879 NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO Adenosine Triphosphate inhibits the reaction [protoporphyrin IX results in decreased activity of HIF1A protein] CTD PMID:23624237 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of HK1 protein; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased activity of CASP1 protein]]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of GSDMD protein]]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of HK1 protein] CTD PMID:37001609 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of HK2 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of HK2 protein CTD PMID:36577999 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
JBrowse link
G Hmgb1 high mobility group box 1 affects chemical synthesis
multiple interactions
ISO HMGB1 protein affects the chemical synthesis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein; Adenosine Triphosphate promotes the reaction [fullerene C60 results in increased secretion of HMGB1 protein]; Adenosine Triphosphate promotes the reaction [graphene oxide results in increased secretion of HMGB1 protein]; Adenosine Triphosphate promotes the reaction [Nanotubes, Carbon results in increased secretion of HMGB1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased cleavage of CASP1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of CASP1 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein]
CTD PMID:21641551 PMID:31504961 PMID:34405489 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of HMOX1 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of HMOX1 protein; Luteolin promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of HMOX1 protein]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of HMOX1 protein]; SR18292 inhibits the reaction [malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of HMOX1 protein]] CTD PMID:34217685 PMID:38135199 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 mRNA]; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of HSPA5 protein] CTD PMID:24149798 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 affects chemical synthesis ISO HSPB1 protein affects the chemical synthesis of Adenosine Triphosphate CTD PMID:21641551 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression
EXP bisindolylmaleimide I inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; chelerythrine inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; Neomycin inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; resveratrol inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein] CTD PMID:16178011 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Fructose results in increased expression of ICAM1 protein] CTD PMID:18508964 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Ifng interferon gamma multiple interactions ISO Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] CTD PMID:14623498 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:17707769 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Il18 interleukin 18 multiple interactions
increases secretion
ISO
EXP
[Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL18 protein; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]
Adenosine Triphosphate results in increased secretion of IL18 protein
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; Ibuprofen inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein]; prim-O-glucosylcimifugin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL18 mRNA]
CTD PMID:17404311 PMID:24149798 PMID:26431797 PMID:27311643 PMID:29378952 More... NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein]; (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein]]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1A protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:26068648 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion
decreases abundance
EXP
ISO
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein; Enzyme Inhibitors inhibits the reaction [IL1B protein results in decreased abundance of Adenosine Triphosphate]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Quercetin inhibits the reaction [IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]]
Adenosine Triphosphate results in increased expression of IL1B protein
Adenosine Triphosphate results in increased secretion of IL1B protein
(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; (N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) inhibits the reaction [Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; [[Air Pollutants results in increased abundance of Particulate Matter] results in increased susceptibility to [Dietary Fats co-treated with Lipopolysaccharides co-treated with Adenosine Triphosphate]] which results in increased secretion of IL1B protein; [[Air Pollutants results in increased abundance of Particulate Matter] results in increased susceptibility to [Lipopolysaccharides co-treated with Adenosine Triphosphate]] which results in increased secretion of IL1B protein; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of and results in increased secretion of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased activity of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Arsenic Trioxide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; dapansutrile inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; ginsenoside Rg3 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Ibuprofen inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; leojaponin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of and affects the cleavage of IL1B protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; Okadaic Acid inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; prim-O-glucosylcimifugin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of IL1B mRNA]; tabersonine inhibits the reaction [Adenosine Triphosphate results in increased expression of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein]]; 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL1B protein modified form; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of IL1B protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; Adenosine Triphosphate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]; Adenosine Triphosphate promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein; Apigenin inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; dapansutrile inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; flavone analog inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; HK1 protein affects the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased cleavage of IL1B protein]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL1B protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; L 709049 inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; neoisoliquiritin affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL1B protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]; Resveratrol promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; SR18292 inhibits the reaction [malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of and results in increased secretion of IL1B protein]]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [Adenosine Triphosphate results in increased cleavage of and results in increased secretion of IL1B protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B mRNA]
CTD PMID:10365824 PMID:14623498 PMID:17404311 PMID:18604214 PMID:19130485 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL6 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of IL6 protein]; NF157 compound inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; Suramin inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]
Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]
[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of IL6 mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein]; MRS 2211 inhibits the reaction [Adenosine Triphosphate results in increased expression of IL6 protein]
CTD PMID:17707769 PMID:24793913 PMID:24849676 PMID:25348860 PMID:26104857 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 multiple interactions
increases secretion
ISO
EXP
Adenosine Triphosphate inhibits the reaction [Glucose results in increased secretion of INS1 protein]
Adenosine Triphosphate results in increased secretion of INS1 protein
[[Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate] which results in increased secretion of LEP protein; [Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate; IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]; Quercetin inhibits the reaction [IL1B protein inhibits the reaction [Adenosine Triphosphate results in increased secretion of INS1 protein]]; SIRT1 protein promotes the reaction [[Glucose results in increased abundance of Adenosine Triphosphate] which results in increased expression of INS1 protein]
CTD PMID:10535451 PMID:10780946 PMID:16366736 PMID:22221676 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [ammonium ferrous sulfate results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate; [chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate; INS protein inhibits the reaction [Acetaminophen results in decreased abundance of Adenosine Triphosphate]; Mannose inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate]; Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] CTD PMID:17965850 PMID:26739624 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
JBrowse link
G Irf2 interferon regulatory factor 2 multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IRF2 mRNA; Hirudins inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IRF2 mRNA] CTD PMID:34212273 NCBI chr16:52,171,855...52,283,620
Ensembl chr16:52,164,442...52,282,627
JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 multiple interactions ISO Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
CTD PMID:23184943 NCBI chr  X:70,612,118...70,617,158
Ensembl chr  X:70,612,521...70,617,158
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of JUN protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of JUN protein] CTD PMID:24149798 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 multiple interactions
increases abundance
ISO [[FAM66C mRNA binds to and results in decreased expression of MIR23 mRNA] which results in increased expression of KCND2 protein] which results in increased abundance of Adenosine Triphosphate; [[MIR23B mRNA binds to KCND2 3' UTR] which results in decreased expression of KCND2 protein] which results in decreased abundance of Adenosine Triphosphate
KCND2 protein results in increased abundance of Adenosine Triphosphate
CTD PMID:34418280 NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:50,742,839...51,243,522
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Adenosine Triphosphate deficiency results in decreased activity of KCNH2 protein CTD PMID:12531891 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions
decreases response to substance
ISO Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]; Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]; Creatine metabolite inhibits the reaction [Adenosine Monophosphate inhibits the reaction [Adenosine Triphosphate results in decreased activity of [KCNJ11 protein binds to ABCC9 protein]]]
KCNJ11 protein mutant form results in decreased susceptibility to Adenosine Triphosphate
CTD PMID:11390963 PMID:28842488 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 increases activity ISO Adenosine Triphosphate results in increased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr11:48,046,953...48,091,285
Ensembl chr11:48,035,655...48,092,457
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 multiple interactions
decreases response to substance
EXP Adenosine Triphosphate results in decreased activity of [KCNJ8 protein binds to ABCC9 protein]
KCNJ8 protein mutant form results in decreased susceptibility to Adenosine Triphosphate
CTD PMID:28842488 NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531
JBrowse link
G Khk ketohexokinase multiple interactions ISO KHK protein promotes the reaction [Fructose results in decreased abundance of Adenosine Triphosphate] CTD PMID:19158351 NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:31,165,248...31,175,481
JBrowse link
G Kif5a kinesin family member 5A multiple interactions
increases hydrolysis
ISO Adenosine Triphosphate inhibits the reaction [zinc chloride results in decreased activity of KIF5A protein]; Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]; Egtazic Acid inhibits the reaction [Cadmium Chloride inhibits the reaction [KIF5A protein results in increased hydrolysis of Adenosine Triphosphate]] CTD PMID:24239783 PMID:28122263 NCBI chr 7:64,937,210...64,974,339
Ensembl chr 7:64,934,740...64,978,272
JBrowse link
G Lep leptin multiple interactions EXP [[Glucose co-treated with INS1 protein] results in increased abundance of Adenosine Triphosphate] which results in increased secretion of LEP protein; [Deoxyglucose results in decreased abundance of Adenosine Triphosphate] which results in decreased secretion of LEP protein CTD PMID:10780946 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
JBrowse link
G Lipe lipase E, hormone sensitive type increases activity ISO Adenosine Triphosphate results in increased activity of LIPE protein CTD PMID:7155675 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117
JBrowse link
G Lpl lipoprotein lipase affects response to substance ISO LPL protein affects the susceptibility to Adenosine Triphosphate CTD PMID:11786490 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects binding ISO Adenosine Triphosphate binds to MAP2K1 protein CTD PMID:17693661 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]; [Alcohols co-treated with Adenosine Triphosphate] results in increased activity of MAPK1 protein; Alcohols inhibits the reaction [Adenosine Triphosphate results in increased activity of MAPK1 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK1 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK1 protein]
CTD PMID:12513686 PMID:15034929 PMID:21503959 PMID:24300283 PMID:26104857 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity
ISO
EXP
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]; [Alcohols co-treated with Adenosine Triphosphate] results in increased activity of MAPK3 protein; Alcohols inhibits the reaction [Adenosine Triphosphate results in increased activity of MAPK3 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]]; sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased phosphorylation of MAPK3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of MAPK3 protein]
CTD PMID:12513686 PMID:15034929 PMID:21503959 PMID:24300283 PMID:26104857 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions
decreases abundance
EXP
ISO
[annonacin results in decreased abundance of Adenosine Triphosphate] which affects the localization of MAPT protein
MAPT protein mutant form results in decreased abundance of Adenosine Triphosphate
PF-06840003 inhibits the reaction [MAPT protein mutant form results in decreased abundance of Adenosine Triphosphate]
CTD PMID:17634376 PMID:39172838 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Adenosine Triphosphate] CTD PMID:30213948 NCBI chr10:107,462,148...107,476,143
Ensembl chr10:107,462,109...107,476,135
JBrowse link
G Mfn2 mitofusin 2 decreases response to substance
multiple interactions
increases chemical synthesis
ISO
EXP
MFN2 results in decreased susceptibility to Adenosine Triphosphate deficiency
MFN2 protein inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate]
MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]
MFN2 protein results in increased chemical synthesis of Adenosine Triphosphate
CTD PMID:22292091 PMID:24898700 PMID:25416777 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
JBrowse link
G Mir219a1 microRNA 219a-1 multiple interactions EXP [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of MIR219A1 mRNA; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein] CTD PMID:35962723 NCBI chr20:4,831,580...4,831,689
Ensembl chr20:4,831,580...4,831,689
JBrowse link
G Mir23b microRNA 23b multiple interactions
decreases abundance
ISO [[MIR23B mRNA binds to KCND2 3' UTR] which results in decreased expression of KCND2 protein] which results in decreased abundance of Adenosine Triphosphate
MIR23B mRNA results in decreased abundance of Adenosine Triphosphate
CTD PMID:34418280 NCBI chr17:1,819,386...1,819,482 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP2 mRNA; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP2 mRNA] CTD PMID:36847822 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity
increases secretion
EXP
ISO
1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; SB 3CT compound inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]; wortmannin inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP9 mRNA; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of MMP9 mRNA]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of MMP9 protein]
Adenosine Triphosphate results in increased secretion of MMP9 protein
CTD PMID:20195827 PMID:26522449 PMID:36847822 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 affects abundance EXP ATP6 protein affects the abundance of Adenosine Triphosphate CTD PMID:18273840 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,904...8,584
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III increases abundance ISO COX3 protein results in increased abundance of Adenosine Triphosphate CTD PMID:17428446 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,584...9,367
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases hydrolysis ISO MVD protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:9392419 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366
JBrowse link
G Mvk mevalonate kinase increases hydrolysis
multiple interactions
ISO MVK protein results in increased hydrolysis of Adenosine Triphosphate
3,3-dimethylallyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; dolichol monophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; Farnesol inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; farnesyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranyl diphosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; geranylgeranyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]; isopentenyl pyrophosphate inhibits the reaction [MVK protein results in increased hydrolysis of Adenosine Triphosphate]
CTD PMID:9392419 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of MYD88 protein; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of MYD88 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of MYD88 protein] CTD PMID:34405489 PMID:37544346 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
JBrowse link
G Myh7 myosin heavy chain 7 increases abundance ISO MYH7 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:29741611 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194
JBrowse link
G Nadsyn1 NAD synthetase 1 multiple interactions ISO [Ammonium Chloride co-treated with nicotinic acid adenine dinucleotide co-treated with Adenosine Triphosphate] results in increased activity of NADSYN1 protein; [NADSYN1 protein co-treated with Ammonium Chloride co-treated with nicotinic acid adenine dinucleotide co-treated with Adenosine Triphosphate] results in increased chemical synthesis of NAD CTD PMID:12547821 NCBI chr 1:208,410,914...208,439,242
Ensembl chr 1:208,410,914...208,439,207
JBrowse link
G Ncs1 neuronal calcium sensor 1 multiple interactions
increases response to substance
EXP NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]; oxophenylarsine inhibits the reaction [NCS1 protein promotes the reaction [Adenosine Triphosphate results in increased secretion of GH1 protein]]
NCS1 protein results in increased susceptibility to Adenosine Triphosphate
CTD PMID:12471042 NCBI chr 3:34,920,949...34,966,554
Ensembl chr 3:34,920,971...34,968,711
JBrowse link
G Nek7 NIMA-related kinase 7 multiple interactions ISO [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] promotes the reaction [NLRP3 protein binds to NEK7 protein] CTD PMID:36627344 NCBI chr13:52,573,730...52,700,869
Ensembl chr13:52,573,730...52,700,823
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 affects localization
multiple interactions
EXP
ISO
Adenosine Triphosphate affects the localization of NFATC1 protein
azetidine analog inhibits the reaction [Adenosine Triphosphate affects the localization of NFATC1 protein]
CTD PMID:21464294 PMID:26522449 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 affects localization EXP Adenosine Triphosphate affects the localization of NFATC3 protein CTD PMID:21464294 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] affects the localization of NFE2L2 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] inhibits the reaction [PPARGC1A protein binds to NFE2L2 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of NFE2L2 protein; Luteolin promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] affects the localization of NFE2L2 protein]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] inhibits the reaction [PPARGC1A protein binds to NFE2L2 protein]]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of NFE2L2 protein]; SR18292 inhibits the reaction [malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of NFE2L2 protein]] CTD PMID:34217685 PMID:38135199 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO
Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]
[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of NFKBIA protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of NFKBIA protein]
CTD PMID:21464294 PMID:24149798 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Ngf nerve growth factor multiple interactions EXP [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium CTD PMID:1374475 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with resveratrol] results in increased expression of NLRP1 mRNA CTD PMID:24149798 NCBI chr10:56,277,134...56,332,229
Ensembl chr10:56,277,134...56,323,880
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO
EXP
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] promotes the reaction [NLRP3 protein binds to NEK7 protein]; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] promotes the reaction [NLRP3 protein binds to PYCARD protein]; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased activity of NLRP3 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of NLRP3 protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; prim-O-glucosylcimifugin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of NLRP3 protein]; tabersonine inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; tabersonine inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased activity of NLRP3 protein]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with Resveratrol] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; neoisoliquiritin affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein]; SR18292 inhibits the reaction [malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]
CTD PMID:18604214 PMID:23430110 PMID:24149798 PMID:26086368 PMID:26586371 More... NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 multiple interactions ISO Adenosine Triphosphate affects the reaction [Doxorubicin binds to NOLC1 protein] CTD PMID:17129415 NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
ISO
EXP
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NOS2 protein; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NOS2 protein]
azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein]
[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; Cyclosporine inhibits the reaction [[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Adenosine Triphosphate results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased abundance of Nitric Oxide]
CTD PMID:21464294 PMID:26522449 PMID:36847822 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Adenosine Triphosphate affects the reaction [Alcohols affects the phosphorylation of NOS3 protein]; Adenosine Triphosphate inhibits the reaction [Alcohols results in decreased expression of NOS3 protein] CTD PMID:24300283 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Npy neuropeptide Y affects response to substance ISO NPY protein affects the susceptibility to Adenosine Triphosphate CTD PMID:15003356 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression EXP Adenosine Triphosphate results in increased expression of NR4A1 mRNA CTD PMID:10723097 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [OAS1 protein results in increased metabolism of Adenosine Triphosphate] which results in increased chemical synthesis of 2',5'-oligoadenylate CTD PMID:15732009 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions
increases secretion
EXP Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] CTD PMID:11102496 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:138,235,754...138,236,594
JBrowse link
G P2rx1 purinergic receptor P2X 1 multiple interactions
affects binding
EXP geldanamycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]; herbimycin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]; monorden promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX1]
ATP binds to P2rx1 protein
CTD
RGD
PMID:11930156 PMID:12237343 RGD:727431 NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164
JBrowse link
G P2rx2 purinergic receptor P2X 2 multiple interactions
affects activity
increases activity
affects response to substance
EXP
ISO
1-amino-4-(3-(4,6-dichloro(1,3,5)triazine-2-ylamino)phenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Acetylcysteine inhibits the reaction [Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Cadmium Chloride affects the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; cobaltous chloride affects the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Copper promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; cupric chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Dithiothreitol inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Mercuric Chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; methyl methanethiosulfonate inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; methyl methanethiosulfonate inhibits the reaction [Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; myxothiazol promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; nickel chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; palladium chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; zinc chloride promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]
ATP affects activity of rat P2x2 receptor in transfected glial cells
P2RX2 protein affects the susceptibility to Adenosine Triphosphate
CTD
RGD
PMID:15081800 PMID:16190872 PMID:19793987 PMID:21207957 PMID:16388598 RGD:1642662 NCBI chr12:51,999,107...52,002,627
Ensembl chr12:51,999,372...52,002,627
JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions
increases activity
affects activity
EXP Eugenol inhibits the reaction [P2RX3 protein affects the activity of Adenosine Triphosphate]
Adenosine Triphosphate results in increased activity of P2RX3 protein
CTD PMID:19967073 PMID:27481062 NCBI chr 3:90,487,506...90,531,315
Ensembl chr 3:90,487,506...90,531,794
JBrowse link
G P2rx4 purinergic receptor P2X 4 multiple interactions
increases activity
EXP
ISO
[Cadmium co-treated with Zinc] promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; [Mercury co-treated with Copper] inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Cadmium promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Cobalt promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Copper inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Copper inhibits the reaction [Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]]; Mercury inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Zinc promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]
5-(3-bromophenyl)-1,3-dihydro-2H-benzofuro(3,2-e)-1,4-diazepin-2-one inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; [ginsenoside compound K co-treated with Adenosine Triphosphate] results in increased activity of P2RX4 protein; [Resveratrol co-treated with Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX4 mRNA; [Resveratrol co-treated with Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX4 protein; ginsenoside compound K promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; ginsenoside Rb1 promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; ginsenoside Rd promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Ivermectin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]
CTD PMID:10737610 PMID:15629187 PMID:19793987 PMID:21638035 PMID:24149798 More... NCBI chr12:39,505,438...39,523,349
Ensembl chr12:39,505,438...39,523,094
JBrowse link
G P2rx5 purinergic receptor P2X 5 affects transport EXP ATP affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr10:58,276,329...58,291,108
Ensembl chr10:58,276,257...58,287,935
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions
increases response to substance
increases expression
decreases response to substance
increases activity
ISO
EXP
[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein; Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein; AZ 11645373 inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; calmidazolium inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; KN 62 inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein]; P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of P2RX7 protein]; ZINC58368839 inhibits the reaction [Adenosine Triphosphate binds to and results in increased activity of P2RX7 protein]
P2RX7 protein results in increased susceptibility to Adenosine Triphosphate
Adenosine Triphosphate results in increased expression of P2RX7 protein
P2RX7 gene mutant form results in decreased susceptibility to Adenosine Triphosphate
3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased expression of P2RX7 protein]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein]
CTD PMID:11003599 PMID:17728465 PMID:19023039 PMID:21638035 PMID:23565201 More... NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions
affects activity
ISO
EXP
[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
Adenosine Triphosphate affects the activity of P2RY1 protein
CTD PMID:12694404 PMID:15243297 PMID:16973929 PMID:22129738 NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027
JBrowse link
G P2ry13 purinergic receptor P2Y13 multiple interactions ISO MRS 2211 inhibits the reaction [P2RY13 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY13 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:22129738 NCBI chr 2:145,620,321...145,624,730
Ensembl chr 2:145,619,655...145,622,787
JBrowse link
G P2ry2 purinergic receptor P2Y2 multiple interactions
affects activity
increases activity
ISO
EXP
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium
Adenosine Triphosphate affects the activity of P2RY2 protein
CTD PMID:11527950 PMID:15243297 PMID:17003265 NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:164,759,213...164,781,852
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 multiple interactions ISO [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:69,722,604...69,757,726
Ensembl chr  X:69,721,753...69,753,510
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 multiple interactions ISO N,N''-1,4-butanediylbis(N'-(3-isothiocyanatophenyl))thiourea inhibits the reaction [P2RY6 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY6 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide] CTD PMID:22129738 NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:164,706,116...164,743,588
JBrowse link
G Panx1 Pannexin 1 decreases activity
multiple interactions
increases export
ISO Adenosine Triphosphate results in decreased activity of PANX1 protein
Carbenoxolone inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]; Probenecid inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]
CTD PMID:19023039 PMID:19213873 NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:20,132,165...20,171,200
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
ISO PARP1 mutant form inhibits the reaction [Cadmium results in decreased abundance of Adenosine Triphosphate]
PARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate]; PARP1 protein affects the reaction [Zinc results in decreased abundance of Adenosine Triphosphate]
Adenosine Triphosphate results in increased expression of PARP1 protein
CTD PMID:17728843 PMID:19809895 PMID:21767558 PMID:22253048 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions
affects response to substance
ISO [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium] CTD PMID:28887310 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO Adenosine Triphosphate promotes the reaction [resveratrol results in decreased activity of PFKM protein] CTD PMID:23454376 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248
JBrowse link
G Pgp phosphoglycolate phosphatase decreases phosphorylation ISO PGP protein results in decreased phosphorylation of Adenosine Triphosphate CTD PMID:24338473 NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha multiple interactions
affects binding
ISO 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Adenosine Triphosphate binds to PIK3CA protein]; Adenosine Triphosphate inhibits the reaction [resveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CA protein]] CTD PMID:17550345 PMID:18754654 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [resveratrol results in decreased activity of [PIK3R1 protein binds to PIK3CA protein]] CTD PMID:17550345 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347
JBrowse link
G Pla2g4a phospholipase A2 group 4A increases activity ISO Adenosine Triphosphate results in increased activity of PLA2G4A protein CTD PMID:10535451 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
JBrowse link
G Plau plasminogen activator, urokinase increases secretion ISO Adenosine Triphosphate results in increased secretion of PLAU protein CTD PMID:20177776 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases chemical synthesis ISO PLPP3 gene mutant form results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:28982073 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
JBrowse link
G Pml PML nuclear body scaffold multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [PML protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PML protein; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased abundance of Reactive Oxygen Species]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein] CTD PMID:23430110 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
JBrowse link
G Pmvk phosphomevalonate kinase increases hydrolysis ISO PMVK protein results in increased hydrolysis of Adenosine Triphosphate CTD PMID:9392419 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate CTD PMID:19593819 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases abundance
ISO FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]; rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]
PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate; PPARG protein results in decreased abundance of Adenosine Triphosphate
CTD PMID:26670611 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [Lipopolysaccharides co-treated with Adenosine Triphosphate] inhibits the reaction [PPARGC1A protein binds to NFE2L2 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PPARGC1A protein; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] inhibits the reaction [PPARGC1A protein binds to NFE2L2 protein]]; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PPARGC1A protein] CTD PMID:38135199 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit multiple interactions ISO Adenosine Triphosphate binds to and affects the folding of PPP5C protein; Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to PPP5C protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to PPP5C protein] CTD PMID:23184943 NCBI chr 1:86,818,297...86,842,505
Ensembl chr 1:86,818,297...86,842,950
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression EXP Adenosine Triphosphate results in increased expression of PRDX2 protein modified form CTD PMID:16178011 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO [[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to Metformin] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Dihydroxyacetone co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate CTD PMID:31974165 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO [[PRKAA1 gene co-treated with PRKAA2 gene] affects the susceptibility to Metformin] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Dihydroxyacetone co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate; [[PRKAA1 gene mutant form co-treated with PRKAA2 gene mutant form] affects the susceptibility to [Glucose co-treated with S 4048]] which results in decreased abundance of Adenosine Triphosphate CTD PMID:31974165 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicin CTD PMID:16087181 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Adenosine Triphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Adenosine Triphosphate] CTD PMID:39172838 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein; resveratrol inhibits the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein] CTD PMID:24149798 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO
EXP
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; malvidin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; neoisoliquiritin affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA]
[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] promotes the reaction [NLRP3 protein binds to PYCARD protein]; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased polymerization of PYCARD protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in decreased expression of PYCARD mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to PYCARD protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to CASP1 protein]]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] promotes the reaction [PYCARD protein binds to PYCARD protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased expression of PYCARD protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; PYCARD gene mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of G(M3) Ganglioside]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; PYCARD protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of PYCARD protein]; tabersonine inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; tabersonine inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased polymerization of PYCARD protein]
CTD PMID:18604214 PMID:23430110 PMID:24149798 PMID:24475307 PMID:29378952 More... NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
JBrowse link
G Ralbp1 ralA binding protein 1 multiple interactions ISO [[Adenosine Triphosphate co-treated with PRKCA protein] results in increased phosphorylation of RALBP1 protein] which results in increased transport of Doxorubicin; Adenosine Triphosphate promotes the reaction [RALBP1 protein affects the transport of Leukotriene C4] CTD PMID:15386349 PMID:16087181 NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:112,903,302...112,939,659
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]; Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to ARRB2 protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NFKBIA protein]]; ARRB2 affects the reaction [Adenosine Triphosphate promotes the reaction [RELA protein binds to NOS2 protein]]; Cyclosporine inhibits the reaction [[Adenosine Triphosphate results in increased expression of NOS2 protein] promotes the reaction [NOS2 protein binds to RELA protein]]
[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein; [Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of and results in increased phosphorylation of RELA protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased phosphorylation of RELA protein; [mitochondrial uncoupler BAM15 co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased phosphorylation of RELA protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of and results in increased phosphorylation of RELA protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased phosphorylation of RELA protein]
[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of RELA protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased phosphorylation of and affects the localization of RELA protein; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased phosphorylation of and affects the localization of RELA protein]; NOS2 protein affects the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]; Resveratrol promotes the reaction [[Adenosine Triphosphate co-treated with Lipopolysaccharides] affects the localization of RELA protein]; S-Nitrosoglutathione promotes the reaction [Adenosine Triphosphate results in increased metabolism of RELA protein]
CTD PMID:21464294 PMID:24149798 PMID:33524445 PMID:34217685 PMID:34405489 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rhof ras homolog family member F, filopodia associated multiple interactions
increases expression
ISO Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of RHOF mRNA] CTD PMID:29733962 NCBI chr12:39,082,413...39,107,528
Ensembl chr12:39,091,979...39,107,528
JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO Adenosine Triphosphate results in increased expression of S100A10 mRNA CTD PMID:29733962 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression ISO Adenosine Triphosphate results in increased expression of S100A11 mRNA CTD PMID:29733962 NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541
JBrowse link
G S100a4 S100 calcium-binding protein A4 multiple interactions
increases expression
ISO Adenosine Triphosphate results in increased expression of and results in increased secretion of S100A4 protein; Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of S100A4 protein]
Adenosine Triphosphate results in increased expression of S100A4 mRNA
CTD PMID:29733962 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO Adenosine Triphosphate results in increased expression of S100A6 mRNA CTD PMID:29733962 NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762
JBrowse link
G Sell selectin L multiple interactions ISO P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased secretion of SELL protein] CTD PMID:11003599 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600
JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions ISO [SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]; Ozone inhibits the reaction [[SFTPA1 protein polymorphism binds to SFTPA2 protein polymorphism] inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]]; Ozone inhibits the reaction [SFTPA1 protein polymorphism inhibits the reaction [Adenosine Triphosphate results in increased secretion of Phosphatidylcholines]] CTD PMID:15065867 NCBI chr16:17,042,264...17,045,770
Ensembl chr16:17,042,255...17,045,769
JBrowse link
G Sftpb surfactant protein B increases secretion
multiple interactions
ISO
EXP
Adenosine Triphosphate results in increased secretion of SFTPB protein
Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPB protein]
CTD PMID:11704537 PMID:14565945 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646
JBrowse link
G Sftpc surfactant protein C increases secretion
multiple interactions
EXP
ISO
Adenosine Triphosphate results in increased secretion of SFTPC protein
Ro 31-8220 inhibits the reaction [Adenosine Triphosphate results in increased secretion of SFTPC protein]
CTD PMID:11704537 PMID:14565945 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP
ISO
[SIRT1 protein results in decreased expression of UCP2 mRNA] promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]; SIRT1 protein promotes the reaction [[Glucose results in increased abundance of Adenosine Triphosphate] which results in increased expression of INS1 protein]; SIRT1 protein promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]
[STK11 protein co-treated with Adenosine Triphosphate] results in increased activity of and results in increased phosphorylation of SIRT1 protein
CTD PMID:16366736 PMID:34216621 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO SIRT3 protein inhibits the reaction [Metformin results in decreased abundance of Adenosine Triphosphate] CTD PMID:23166782 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Slc25a14 solute carrier family 25 member 14 decreases chemical synthesis ISO SLC25A14 protein results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:20600837 NCBI chr  X:132,685,518...132,723,705
Ensembl chr  X:132,676,818...132,723,703
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases stability ISO Adenosine Triphosphate results in decreased stability of SLC2A1 protein CTD PMID:11420438 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases abundance ISO SLC2A4 protein results in increased abundance of Adenosine Triphosphate CTD PMID:34904774 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270
JBrowse link
G Slc46a1 solute carrier family 46 member 1 multiple interactions ISO [SLC46A1 protein results in increased susceptibility to N-((5-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophen-2-yl)carbonyl)glutamic acid] which results in decreased chemical synthesis of Adenosine Triphosphate CTD PMID:21879757 NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869
JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] CTD PMID:16439463 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691
JBrowse link
G Snca synuclein alpha multiple interactions
decreases abundance
ISO GW8510 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate]; SB 216763 inhibits the reaction [SNCA protein results in decreased abundance of Adenosine Triphosphate] CTD PMID:24989254 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP
ISO
Adenosine Triphosphate results in increased expression of SOD1 protein CTD PMID:16178011 PMID:22129738 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 affects chemical synthesis
decreases abundance
multiple interactions
ISO SOD2 protein affects the chemical synthesis of Adenosine Triphosphate
SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate
MK-886 promotes the reaction [SOD2 gene mutant form results in decreased abundance of Adenosine Triphosphate]
CTD PMID:20638473 PMID:25362851 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Srr serine racemase multiple interactions ISO Adenosine Triphosphate inhibits the reaction [Edetic Acid inhibits the reaction [SRR protein results in increased abundance of D-Aspartic Acid]]; Adenosine Triphosphate promotes the reaction [SRR protein results in increased abundance of D-Aspartic Acid] CTD PMID:27387750 NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO [STK11 protein co-treated with Adenosine Triphosphate] results in increased activity of and results in increased phosphorylation of SIRT1 protein CTD PMID:34216621 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965
JBrowse link
G Stxbp2 syntaxin binding protein 2 multiple interactions ISO STXBP2 protein affects the reaction [F2 protein results in increased transport of Adenosine Triphosphate] CTD PMID:30696774 NCBI chr12:6,487,265...6,498,351
Ensembl chr12:6,487,297...6,504,212
JBrowse link
G Sugt1 SGT1 homolog, MIS12 kinetochore complex assembly cochaperone multiple interactions ISO Adenosine Triphosphate promotes the reaction [CHORDC1 protein binds to SUGT1 protein]; Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]] CTD PMID:23184943 NCBI chr15:61,400,478...61,441,303
Ensembl chr15:61,400,004...61,468,852
JBrowse link
G Syn2 synapsin II multiple interactions ISO SYN2 mutant form inhibits the reaction [Adenosine Triphosphate results in increased abundance of Calcium] CTD PMID:18701217 NCBI chr 4:149,858,919...150,016,845
Ensembl chr 4:149,851,520...150,019,650
JBrowse link
G Tac1 tachykinin, precursor 1 increases secretion
multiple interactions
EXP Adenosine Triphosphate results in increased secretion of TAC1 protein
Iloprost promotes the reaction [Adenosine Triphosphate results in increased secretion of TAC1 protein]
CTD PMID:16039053 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546
JBrowse link
G Taldo1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of Adenosine Triphosphate CTD PMID:19436114 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535
JBrowse link
G Tas2r145 taste receptor, type 2, member 145 increases activity ISO Adenosine Triphosphate results in increased activity of TAS2R131 protein CTD PMID:29347925 NCBI chr 4:167,869,406...167,870,356
Ensembl chr 4:167,869,358...167,870,544
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased abundance of Adenosine Triphosphate CTD PMID:35366062 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A multiple interactions
decreases expression
ISO 1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in decreased expression of TIMM17A protein] CTD PMID:24315374 NCBI chr13:49,282,918...49,296,363
Ensembl chr13:49,282,918...49,307,904
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases secretion
multiple interactions
ISO Adenosine Triphosphate results in decreased secretion of TIMP1 protein
azetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein]
CTD PMID:26522449 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA; [Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TLR4 protein; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TLR4 protein]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 mRNA]; sodium houttuyfonate inhibits the reaction [[Adenosine Triphosphate co-treated with HMGB1 protein] results in increased expression of TLR4 protein] CTD PMID:34405489 PMID:37544346 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases chemical synthesis
ISO
EXP
[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TNF mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; Adenosine Triphosphate deficiency inhibits the reaction [TNF protein results in increased transport of Chlorides]; Adenosine Triphosphate deficiency inhibits the reaction [TNF protein results in increased transport of Potassium]; Adenosine Triphosphate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; azetidine analog inhibits the reaction [Adenosine Triphosphate results in increased secretion of TNF protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased expression of TNF mRNA]; fuzheng huayu inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; ginsenoside Rg3 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; gypenoside LXXV inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; mitochondrial uncoupler BAM15 inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]
Adenosine Triphosphate inhibits the reaction [Sunitinib results in increased expression of TNF protein]; TNF protein promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased chemical synthesis of Adenosine Triphosphate]
TNF protein results in decreased chemical synthesis of Adenosine Triphosphate
[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of TNF protein; [Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein; Adenosine Triphosphate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of TNF protein]; MFN2 protein inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]; Rosiglitazone inhibits the reaction [TNF protein results in decreased chemical synthesis of Adenosine Triphosphate]; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate]
CTD PMID:8817062 PMID:10783394 PMID:14623498 PMID:17707769 PMID:23430110 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf11 TNF superfamily member 11 increases abundance ISO TNFSF11 protein results in increased abundance of Adenosine Triphosphate CTD PMID:26287518 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
increases hydrolysis
ISO Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; copper-thiosemicarbazone complex analog inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Dithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]; Emodin inhibits the reaction [TOP2A results in increased hydrolysis of Adenosine Triphosphate]; Etoposide metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Thiosemicarbazones analog inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]
TOP2A protein results in increased hydrolysis of Adenosine Triphosphate; TOP2A results in increased hydrolysis of Adenosine Triphosphate
CTD PMID:20855424 PMID:26982206 PMID:27533850 PMID:29272108 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
JBrowse link
G Top2b DNA topoisomerase II beta increases hydrolysis
multiple interactions
ISO TOP2B protein results in increased hydrolysis of Adenosine Triphosphate
cannabidiol hydroxyquinone inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate]; Cannabidiol metabolite inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate]
CTD PMID:29272108 NCBI chr15:11,482,089...11,542,464
Ensembl chr15:11,482,089...11,542,464
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases abundance
ISO TP53 protein inhibits the reaction [Deoxyglucose results in decreased abundance of Adenosine Triphosphate]
TP53 gene mutant form results in increased abundance of Adenosine Triphosphate
CTD PMID:21042727 PMID:33070465 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; AZ10606120 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Triphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 multiple interactions
increases activity
ISO ethyl-1-(4-(2*3*3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate inhibits the reaction [Adenosine Triphosphate results in increased activity of TRPC3 protein] CTD PMID:19289841 NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:121,409,436...121,475,823
JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 increases activity ISO Adenosine Triphosphate results in increased activity of TRPC5 protein CTD PMID:19289841 NCBI chr  X:112,742,828...113,027,638
Ensembl chr  X:112,742,828...113,027,638
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 increases activity ISO Adenosine Triphosphate results in increased activity of TRPC6 protein CTD PMID:19289841 NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:14,043,877...14,149,304
JBrowse link
G Trpc7 transient receptor potential cation channel, subfamily C, member 7 increases activity ISO Adenosine Triphosphate results in increased activity of TRPC7 protein CTD PMID:19289841 NCBI chr17:7,707,954...7,839,064
Ensembl chr17:7,714,505...7,838,745
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 decreases activity ISO
EXP
Adenosine Triphosphate results in decreased activity of TRPM4 protein CTD PMID:16966582 PMID:17188667 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:104,918,462...104,948,653
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP [Capsaicin binds to and affects the activity of TRPV1 protein] which results in increased secretion of Adenosine Triphosphate CTD PMID:19860742 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO Adenosine Triphosphate inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein] CTD PMID:16439463 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO Adenosine Triphosphate results in increased expression of TXN protein CTD PMID:22129738 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
G Txnip thioredoxin interacting protein increases activity EXP Adenosine Triphosphate results in increased activity of TXNIP mRNA CTD PMID:21832250 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions
decreases abundance
EXP
ISO
Adenosine Triphosphate inhibits the reaction [UCP1 protein results in increased transport of Protons]
UCP1 results in decreased abundance of Adenosine Triphosphate
UCP1 protein promotes the reaction [PPARG protein mutant form results in decreased abundance of Adenosine Triphosphate]; UCP1 protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]
CTD PMID:12734183 PMID:26670611 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO
EXP
Adenosine Triphosphate inhibits the reaction [UCP2 protein results in increased transport of Protons]
[SIRT1 protein results in decreased expression of UCP2 mRNA] promotes the reaction [Glucose results in increased abundance of Adenosine Triphosphate]
CTD PMID:12734183 PMID:16366736 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
JBrowse link
G Ucp3 uncoupling protein 3 multiple interactions ISO Adenosine Triphosphate inhibits the reaction [UCP3 protein results in increased transport of Protons] CTD PMID:12734183 NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:164,227,882...164,241,210
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO VDAC1 mutant form inhibits the reaction [chromium hexavalent ion results in decreased abundance of Adenosine Triphosphate] CTD PMID:22858589 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 multiple interactions
increases abundance
decreases abundance
ISO Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in decreased abundance of Adenosine Triphosphate]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased abundance of Adenosine Triphosphate] CTD PMID:30998386 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613
JBrowse link
butyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B affects binding ISO butyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
JBrowse link
cangrelor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor multiple interactions ISO cangrelor results in decreased expression of and results in decreased activity of F3 protein; Indomethacin promotes the reaction [cangrelor results in decreased expression of and results in decreased activity of F3 protein] CTD PMID:20200314 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
JBrowse link
G Gpr17 G protein-coupled receptor 17 multiple interactions ISO cangrelor inhibits the reaction [Uridine Diphosphate results in increased activity of GPR17 protein] CTD PMID:18974869 NCBI chr18:23,850,460...23,857,381
Ensembl chr18:23,850,107...23,857,702
JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] CTD PMID:18404433 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
JBrowse link
G P2ry12 purinergic receptor P2Y12 multiple interactions
decreases activity
affects response to substance
ISO [cangrelor binds to and results in decreased activity of P2RY12 protein] which results in decreased abundance of phosphatidylinositol 3,4,5-triphosphate; [cangrelor binds to and results in decreased activity of P2RY12 protein] which results in decreased phosphorylation of SYK protein
cangrelor results in decreased activity of P2RY12 protein
P2RY12 gene polymorphism affects the susceptibility to cangrelor
CTD PMID:12606772 PMID:20126830 PMID:22273509 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:145,629,967...145,633,410
JBrowse link
G Pf4 platelet factor 4 multiple interactions ISO cangrelor inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased secretion of PF4 protein] CTD PMID:22273509 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392
JBrowse link
G Selp selectin P multiple interactions ISO cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]] CTD PMID:18404433 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987
JBrowse link
G Syk spleen associated tyrosine kinase multiple interactions ISO [cangrelor binds to and results in decreased activity of P2RY12 protein] which results in decreased phosphorylation of SYK protein CTD PMID:12606772 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278
JBrowse link
CGS-21680 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 increases response to substance
multiple interactions
ISO ADCY5 protein results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine
ADCY5 protein results in increased susceptibility to [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with Quinpirole]
CTD PMID:12223546 NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343
JBrowse link
G Adora2a adenosine A2a receptor increases response to substance
multiple interactions
ISO
EXP
ADORA2A protein results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of ADORA2A protein]; 8-(3-chlorostyryl)caffeine inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]]; 8-(3-chlorostyryl)caffeine inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]]; PRKCZ protein affects the reaction [[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein] which results in decreased expression of VEGFA mRNA]
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of ADORA2A protein]
CTD PMID:11172060 PMID:12590138 PMID:15452191 PMID:19749167 PMID:19966059 More... NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of BDNF mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of BDNF protein] CTD PMID:35917217 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
JBrowse link
G Becn1 beclin 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of BECN1 protein] CTD PMID:30555576 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression
multiple interactions
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of BMAL1 mRNA
[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in increased expression of BMAL1 mRNA
CTD PMID:22923002 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]] CTD PMID:30555576 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Clock clock circadian regulator increases expression ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of CLOCK mRNA CTD PMID:22923002 NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein
CTNNB1 protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein]
CTD PMID:27595240 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of CREB1 mRNA] CTD PMID:35917217 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Ctnnb1 catenin beta 1 affects localization
multiple interactions
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine affects the localization of CTNNB1 protein modified form
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of and affects the phosphorylation of CTNNB1 protein; CTNNB1 protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein]
CTD PMID:27595240 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 protein] CTD PMID:19035488 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in increased expression of EDN1 protein] CTD PMID:39332792 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in increased expression of EDNRA protein] CTD PMID:39332792 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284
JBrowse link
G Ednrb endothelin receptor type B multiple interactions ISO [Phosphorus, Dietary co-treated with Cisplatin co-treated with 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine] results in increased expression of EDNRB protein CTD PMID:39332792 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions
increases response to substance
decreases response to substance
ISO 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [EPHX2 gene results in decreased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine]; 14,15-eicosa-5-enoic acid inhibits the reaction [EPHX2 gene mutant form results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine]; 4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [EPHX2 gene results in decreased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine]; T 0070907 inhibits the reaction [EPHX2 gene mutant form results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine] CTD PMID:23152114 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA] CTD PMID:15452191 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in increased expression of HAVCR1 protein] CTD PMID:39332792 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of HMGCR mRNA] CTD PMID:30825513 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of HMGCS1 mRNA] CTD PMID:30825513 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
JBrowse link
G Il10 interleukin 10 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [TNF protein results in increased expression of IL10 mRNA] CTD PMID:22923002 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il12a interleukin 12A multiple interactions ISO [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in decreased expression of IL12A mRNA CTD PMID:22923002 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
JBrowse link
G Lep leptin multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of LEP mRNA] CTD PMID:26367767 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased cleavage of MAP1LC3B protein] CTD PMID:30555576 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases activity ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased activity of MMP14 protein CTD PMID:16783407 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased activity of MMP2 protein CTD PMID:16783407 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
decreases expression
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased activity of MMP9 protein
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of MMP9 mRNA
CTD PMID:16783407 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in increased expression of NOS2 protein] CTD PMID:39332792 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in decreased expression of NOS3 protein] CTD PMID:39332792 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Caffeine analog inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]] CTD PMID:15452191 PMID:19966059 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of NR1D1 mRNA CTD PMID:22923002 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions
increases expression
EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of NTRK2 mRNA]
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of NTRK2 mRNA
CTD PMID:35917217 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
JBrowse link
G Per2 period circadian regulator 2 decreases expression ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of PER2 mRNA CTD PMID:22923002 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine affects the localization of and results in increased activity of PRKCE protein CTD PMID:12590138 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288
JBrowse link
G Prkcz protein kinase C, zeta multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine affects the localization of and results in increased activity of PRKCZ protein; PRKCZ protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of VEGFA mRNA]; PRKCZ protein affects the reaction [[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein] which results in decreased expression of VEGFA mRNA] CTD PMID:12590138 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674
JBrowse link
G Ren renin multiple interactions
increases expression
EXP Atenolol inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of REN protein] CTD PMID:9300315 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA] CTD PMID:15452191 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of SIRT1 mRNA] CTD PMID:30825513 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in decreased expression of SIRT3 protein]] CTD PMID:30555576 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of SLC9A1 protein] CTD PMID:15452191 NCBI chr 5:150,859,412...150,913,525
Ensembl chr 5:150,860,228...150,913,517
JBrowse link
G Smad3 SMAD family member 3 multiple interactions EXP 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of SMAD3 protein] CTD PMID:22063920 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of SOCS3 mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of SOCS3 protein] CTD PMID:27289578 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of SREBF2 mRNA] CTD PMID:30825513 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in increased expression of TGFB1 protein] CTD PMID:39332792 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [TNF protein results in increased expression of IL10 mRNA]; [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in decreased expression of IL12A mRNA; [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in increased expression of BMAL1 mRNA
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [[Phosphorus, Dietary co-treated with Cisplatin] results in increased expression of TNF protein]
CTD PMID:21538184 PMID:22923002 PMID:39332792 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TP53 protein]] CTD PMID:30555576 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Vegfa vascular endothelial growth factor A increases secretion
decreases expression
multiple interactions
ISO
EXP
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased secretion of VEGFA protein
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of VEGFA mRNA
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; PRKCZ protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of VEGFA mRNA]; PRKCZ protein affects the reaction [[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein] which results in decreased expression of VEGFA mRNA]
CTD PMID:12590138 PMID:20067761 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
coenzyme A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of Coenzyme A analog CTD PMID:16141203 NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:173,950,531...173,962,570
JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
JBrowse link
cyclic ADP-beta-D-ribose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd38 CD38 molecule decreases abundance ISO CD38 gene mutant form results in decreased abundance of Cyclic ADP-Ribose CTD PMID:23343681 NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:26,278,105...26,381,657
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions EXP HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705
JBrowse link
D-ribofuranose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
ISO [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]
Ribose results in increased expression of AGER protein
CTD PMID:30101366 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
JBrowse link
G B2m beta-2 microglobulin increases glycation ISO Ribose results in increased glycation of B2M protein CTD PMID:21864514 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [Creatine co-treated with Ribose] results in decreased activity of CASP3 protein CTD PMID:21220914 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases phosphorylation ISO Ribose results in increased phosphorylation of CHUK protein CTD PMID:30101366 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation ISO Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
JBrowse link
G Ins1 insulin 1 increases secretion ISO Ribose results in increased secretion of INS1 protein CTD PMID:30101366 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions
ISO Ribose results in increased phosphorylation of NFKBIA protein
[Ribose co-treated with Glucose] results in increased phosphorylation of NFKBIA protein
CTD PMID:30101366 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Ribose inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
ISO [Ribose co-treated with Glucose] affects the localization of RELA protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]]; Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]
Ribose results in increased phosphorylation of RELA protein
CTD PMID:30101366 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
D-ribofuranose 5-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Taldo1 transaldolase 1 increases abundance ISO TALDO1 gene mutant form results in increased abundance of ribose-5-phosphate CTD PMID:19436114 NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535
JBrowse link
decanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [decanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
JBrowse link
glutaryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
JBrowse link
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:173,950,531...173,962,570
JBrowse link
guanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP Guanosine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein] CTD PMID:25174304 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E affects binding
multiple interactions
ISO Guanosine analog binds to EIF4E protein
Guanosine analog inhibits the reaction [7-methylguanosine 5'-diphosphate analog binds to EIF4E protein]; Guanosine analog inhibits the reaction [RNA Caps binds to EIF4E protein]
CTD PMID:27592390 NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions ISO [Guanosine co-treated with Ketamine] results in increased activity of GLUL protein CTD PMID:36878458 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Guanosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 decreases expression EXP Guanosine results in decreased expression of IMPDH2 mRNA CTD PMID:11145582 NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO Guanosine inhibits the reaction [tiazofurin results in decreased expression of KRAS] CTD PMID:9381980 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Guanosine results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:18456249 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Guanosine results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:18456249 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO Guanosine inhibits the reaction [tiazofurin results in decreased expression of MYC] CTD PMID:9381980 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions ISO [Guanosine co-treated with Ketamine] results in increased expression of SLC1A2 protein CTD PMID:36878458 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249
JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO
EXP
Guanosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:11085929 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO Guanosine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:211,757,000...211,764,560
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Guanosine CTD PMID:19164483 NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Guanosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
JBrowse link
G Upp1 uridine phosphorylase 1 increases metabolic processing ISO UPP1 protein results in increased metabolism of Guanosine CTD PMID:15772079 NCBI chr14:88,023,155...88,043,036
Ensembl chr14:88,023,351...88,043,034
JBrowse link
hexanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
JBrowse link
inosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase decreases abundance
increases abundance
ISO ADA alternative form results in decreased abundance of Inosine
ADA protein results in increased abundance of Inosine
CTD PMID:16221767 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Inosine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Inosine] CTD PMID:39172838 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Faslg Fas ligand increases expression ISO Inosine results in increased expression of FASLG protein CTD PMID:16419169 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Inosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form] CTD PMID:32941855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Inosine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Inosine] CTD PMID:39172838 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189
JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO
EXP
Inosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:11085929 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO Inosine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:211,757,000...211,764,560
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO Inosine inhibits the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein] CTD PMID:32941855 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
JBrowse link
isobutyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B affects binding ISO isobutyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,799,145...6,903,616
JBrowse link
lauroyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [lauroyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806
JBrowse link
malonyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlycd malonyl-CoA decarboxylase multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] CTD PMID:14641110 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
methacrylyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl-CoA hydratase, short chain 1 increases abundance ISO ECHS1 gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A CTD PMID:25125611 NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886
JBrowse link
myristoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbi diazepam binding inhibitor affects binding ISO S-tetradecanoyl-coenzyme A binds to DBI protein CTD PMID:17044054 NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
N(6),N(6)-dimethyladenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 decreases expression
multiple interactions
ISO N(6),N(6)-dimethyladenosine results in decreased expression of ADAM17 protein
N(6),N(6)-dimethyladenosine inhibits the reaction [Cycloheximide results in decreased stability of ADAM17 protein]
CTD PMID:36558177 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344
JBrowse link
G Bsg basigin decreases expression ISO N(6),N(6)-dimethyladenosine results in decreased expression of BSG protein CTD PMID:36574092 NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
JBrowse link
N-ethyl-5'-carboxamidoadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor affects response to substance ISO ADORA2B protein affects the susceptibility to Adenosine-5'-(N-ethylcarboxamide) CTD PMID:16920807 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091
JBrowse link
G Adora3 adenosine A3 receptor affects binding ISO Adenosine-5'-(N-ethylcarboxamide) binds to ADORA3 protein CTD PMID:21186795 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686
JBrowse link
G Casp1 caspase 1 increases activity EXP Adenosine-5'-(N-ethylcarboxamide) results in increased activity of CASP1 mRNA; Adenosine-5'-(N-ethylcarboxamide) results in increased activity of CASP1 protein CTD PMID:21832250 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of CCL2 protein CTD PMID:17696452 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ephx2 epoxide hydrolase 2 increases response to substance ISO EPHX2 gene mutant form results in increased susceptibility to Adenosine-5'-(N-ethylcarboxamide) CTD PMID:23152114 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
JBrowse link
G Gna11 G protein subunit alpha 11 decreases expression
multiple interactions
EXP Adenosine-5'-(N-ethylcarboxamide) results in decreased expression of GNA11 protein
Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [Fluoxetine results in decreased expression of GNA11 protein]
CTD PMID:21712787 NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,814,327...8,830,558
JBrowse link
G Gnaq G protein subunit alpha q decreases expression
multiple interactions
EXP Adenosine-5'-(N-ethylcarboxamide) results in decreased expression of GNAQ protein
Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [Fluoxetine results in decreased expression of GNAQ protein]
CTD PMID:21712787 NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:222,852,097...223,126,742
JBrowse link
G Il13 interleukin 13 increases secretion ISO Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of IL13 protein CTD PMID:17696452 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
JBrowse link
G Sftpb surfactant protein B increases secretion
multiple interactions
EXP
ISO
Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of SFTPB protein
Ro 31-8220 inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of SFTPB protein]
CTD PMID:11704537 PMID:14565945 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646
JBrowse link
G Sftpc surfactant protein C increases secretion
multiple interactions
ISO
EXP
Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of SFTPC protein
Ro 31-8220 inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) results in increased secretion of SFTPC protein]
CTD PMID:11704537 PMID:14565945 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; ZM 241385 inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]] CTD PMID:21538184 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf11 TNF superfamily member 11 increases expression EXP Adenosine-5'-(N-ethylcarboxamide) results in increased expression of TNFSF11 mRNA; Adenosine-5'-(N-ethylcarboxamide) results in increased expression of TNFSF11 protein CTD PMID:29649498 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Txnip thioredoxin interacting protein increases activity EXP Adenosine-5'-(N-ethylcarboxamide) results in increased activity of TXNIP mRNA CTD PMID:21832250 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [Cyclosporine results in decreased expression of VEGFA mRNA]; Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [Cyclosporine results in decreased expression of VEGFA protein]; N-(4-cyanophenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-phenoxy)acetamide inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [Cyclosporine results in decreased expression of VEGFA mRNA]]; N-(4-cyanophenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-phenoxy)acetamide inhibits the reaction [Adenosine-5'-(N-ethylcarboxamide) inhibits the reaction [Cyclosporine results in decreased expression of VEGFA protein]] CTD PMID:26311998 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
oleoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO oleoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO oleoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO oleoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
P(1),P(4)-bis(5'-adenosyl) tetraphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein] CTD PMID:19442829 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Nudt2 nudix hydrolase 2 increases hydrolysis ISO NUDT2 protein results in increased hydrolysis of diadenosine tetraphosphate CTD PMID:20533549 NCBI chr 5:61,424,176...61,439,018
Ensembl chr 5:61,424,053...61,439,015
JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:19442829 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
JBrowse link
P(1),P(5)-bis(5'-adenosyl) pentaphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator multiple interactions ISO P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] CTD PMID:15684079 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643
JBrowse link
G Nudt11 nudix hydrolase 11 multiple interactions
increases metabolic processing
ISO [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of adenosine 5'-tetraphosphate; [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate; manganese chloride promotes the reaction [NUDT11 protein results in increased metabolism of P(1),P(5)-di(adenosine-5'-)pentaphosphate] CTD PMID:12121577 NCBI chr  X:18,998,587...19,005,208
Ensembl chr  X:18,998,461...19,005,208
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP P(1),P(5)-di(adenosine-5'-)pentaphosphate analog inhibits the reaction [[Nitrites co-treated with Oxygen deficiency] results in increased expression of SIRT1 mRNA] CTD PMID:22892143 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
P(1),P(6)-bis(5'-adenosyl)hexaphosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt11 nudix hydrolase 11 multiple interactions
increases metabolic processing
ISO [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of adenosine 5'-pentaphosphate; [NUDT11 protein results in increased metabolism of diadenosine 5',5''''-P1,P6-hexaphosphate] which results in increased chemical synthesis of Adenosine Monophosphate CTD PMID:12121577 NCBI chr  X:18,998,587...19,005,208
Ensembl chr  X:18,998,461...19,005,208
JBrowse link
palmitoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases metabolic processing
multiple interactions
ISO ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A
[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]
CTD PMID:10497882 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136
JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis EXP CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A CTD PMID:8611161 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A] CTD PMID:19854160 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] CTD PMID:16214399 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein CTD PMID:17992261 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein
Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
CTD PMID:11139385 PMID:18812576 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Shbg sex hormone binding globulin decreases expression ISO Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein CTD PMID:17992261 NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760
JBrowse link
stearoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO stearoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO stearoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
succinyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of succinyl-coenzyme A CTD PMID:16141203 NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
JBrowse link
tiazofurine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kras KRAS proto-oncogene, GTPase multiple interactions
decreases expression
ISO Guanosine inhibits the reaction [tiazofurin results in decreased expression of KRAS] CTD PMID:9381980 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO tiazofurin results in decreased expression of MYC
Guanosine inhibits the reaction [tiazofurin results in decreased expression of MYC]
CTD PMID:9381980 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
TNP-ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx1 purinergic receptor P2X 1 affects binding EXP TNP-ATP binds to P2rx1 protein RGD PMID:12237343 RGD:727431 NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164
JBrowse link
G P2rx2 purinergic receptor P2X 2 multiple interactions EXP TNP-ATP binds to P2rx2 protein; TNP-ATP inhibits the reaction [ATP binds to P2rx2 protein] in transfected glial cells RGD PMID:16388598 RGD:1642662 NCBI chr12:51,999,107...52,002,627
Ensembl chr12:51,999,372...52,002,627
JBrowse link
G P2rx5 purinergic receptor P2X 5 affects transport EXP TNP-ATP affects transport ion flux of P2rx5 receptor RGD PMID:12237343 RGD:727431 NCBI chr10:58,276,329...58,291,108
Ensembl chr10:58,276,257...58,287,935
JBrowse link
xanthosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP xanthosine inhibits the reaction [Palmitates results in decreased phosphorylation of AKT1 protein] CTD PMID:36627075 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP xanthosine inhibits the reaction [Palmitates results in decreased phosphorylation of FOXO1 protein] CTD PMID:36627075 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP xanthosine inhibits the reaction [Palmitates results in increased expression of G6PC1 protein] CTD PMID:36627075 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP xanthosine inhibits the reaction [Palmitates results in decreased phosphorylation of GSK3B protein] CTD PMID:36627075 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
JBrowse link
G Gys1 glycogen synthase 1 multiple interactions EXP xanthosine inhibits the reaction [Palmitates results in increased phosphorylation of GYS1 protein] CTD PMID:36627075 NCBI chr 1:105,051,916...105,071,763
Ensembl chr 1:105,051,961...105,072,419
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions EXP xanthosine inhibits the reaction [Palmitates results in increased expression of PCK2 protein] CTD PMID:36627075 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        biochemical role 20264
          metabolite 20245
            fundamental metabolite 14805
              D-ribose 772
                2-deoxy-D-ribofuranose 5-phosphate + 0
                2-deoxy-D-ribose + 0
                2-deoxy-D-ribose 1,5-bisphosphate 0
                2-deoxy-D-ribose 5-phosphate + 0
                5-deoxy-D-ribose 0
                D-hamamelose + 0
                D-ribofuranose + 772
                D-ribofuranose-2,5-bisphosphate 0
                D-ribopyranose + 0
                D-ribose 1,5-bisphosphate + 0
                D-ribose 1-diphosphate + 0
                D-ribose 1-phosphate + 0
                D-ribose 5-diphosphate 0
                D-ribose 5-phosphate + 1
                D-ribose 5-triphosphate + 0
                S-methyl-5-thio-D-ribofuranose + 0
                S-methyl-5-thio-D-ribose 0
                S-methyl-5-thio-alpha-D-ribose 1-phosphate 0
                aldehydo-D-ribose + 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbohydrates and carbohydrate derivatives 15487
                                    carbohydrate 15487
                                      monosaccharide 5123
                                        aldose 3497
                                          aldopentose 776
                                            ribose 774
                                              D-ribose 772
                                                2-deoxy-D-ribofuranose 5-phosphate + 0
                                                2-deoxy-D-ribose + 0
                                                2-deoxy-D-ribose 1,5-bisphosphate 0
                                                2-deoxy-D-ribose 5-phosphate + 0
                                                5-deoxy-D-ribose 0
                                                D-hamamelose + 0
                                                D-ribofuranose + 772
                                                D-ribofuranose-2,5-bisphosphate 0
                                                D-ribopyranose + 0
                                                D-ribose 1,5-bisphosphate + 0
                                                D-ribose 1-diphosphate + 0
                                                D-ribose 1-phosphate + 0
                                                D-ribose 5-diphosphate 0
                                                D-ribose 5-phosphate + 1
                                                D-ribose 5-triphosphate + 0
                                                S-methyl-5-thio-D-ribofuranose + 0
                                                S-methyl-5-thio-D-ribose 0
                                                S-methyl-5-thio-alpha-D-ribose 1-phosphate 0
                                                aldehydo-D-ribose + 9
paths to the root