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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:11-deoxycorticosterone
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Accession:CHEBI:16973 term browser browse the term
Definition:A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.
Synonyms:exact_synonym: 21-hydroxypregn-4-ene-3,20-dione
 related_synonym: 21-Hydroxy-4-pregnene-3,20-dione;   21-hydroxyprogesterone;   4-pregnen-21-ol-3,20-dione;   Cortexone;   DESOXYCORTICOSTERONE;   DOC;   Deoxycorticosterone;   Formula=C21H30O3;   InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1;   InChIKey=ZESRJSPZRDMNHY-YFWFAHHUSA-N;   Kendall's desoxy compound B;   Reichstein's substance Q;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)CO;   desoxycortone
 alt_id: CHEBI:11314;   CHEBI:19123;   CHEBI:39642;   CHEBI:713;   CHEBI:86536
 xref: Beilstein:2062123;   CAS:64-85-7;   Drug_Central:820;   KEGG:C03205;   KEGG:D07792;   LIPID_MAPS_instance:LMST02030087
 xref_mesh: MESH:D003900
 xref: MetaCyc:11-DEOXYCORTICOSTERONE;   PDBeChem:1CA;   PMID:22770225;   Reaxys:2062123;   Wikipedia:Desoxycorticosterone


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11-deoxycorticosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions		 ISO Desoxycorticosterone results in increased expression of ACTA2 mRNA; Desoxycorticosterone results in increased expression of ACTA2 protein
Rotenone inhibits the reaction [Desoxycorticosterone results in increased expression of ACTA2 protein]		 CTD PMID:17596522 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Agt angiotensinogen increases activity EXP Desoxycorticosterone results in increased activity of AGT protein CTD PMID:9087624 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases metabolic processing ISO AKR1C18 protein results in increased metabolism of Desoxycorticosterone CTD PMID:17122075 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Ar androgen receptor multiple interactions ISO Desoxycorticosterone binds to and results in increased activity of AR protein mutant form CTD PMID:11956172 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein] CTD PMID:22431579 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]; Atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein] CTD PMID:22431579 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cat catalase multiple interactions EXP CAT protein results in increased susceptibility to [tert-Butylhydroperoxide co-treated with Desoxycorticosterone co-treated with tempol] CTD PMID:12646410 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 mRNA; [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 protein] CTD PMID:21135038 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions		 ISO Desoxycorticosterone results in decreased expression of CDH1 mRNA; Desoxycorticosterone results in decreased expression of CDH1 protein
Rotenone inhibits the reaction [Desoxycorticosterone results in decreased expression of CDH1 protein]		 CTD PMID:17596522 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions		 EXP Desoxycorticosterone results in increased expression of CYBA mRNA; Desoxycorticosterone results in increased expression of CYBA protein
[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of CYBA protein		 CTD PMID:16271043 PMID:22431579 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 affects metabolic processing
multiple interactions
increases chemical synthesis		 ISO
EXP		 CYP11B1 protein affects the metabolism of Desoxycorticosterone
Plant Extracts inhibits the reaction [Desoxycorticosterone binds to CYP11B1 protein]
CYP11B1 protein results in increased chemical synthesis of Desoxycorticosterone		 CTD PMID:15666820 PMID:16054388 PMID:19900470 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 affects metabolic processing
increases hydroxylation
multiple interactions		 ISO CYP11B2 protein affects the metabolism of Desoxycorticosterone
CYP11B2 protein results in increased hydroxylation of Desoxycorticosterone
[CYP11B2 protein results in increased hydroxylation of Desoxycorticosterone] which results in increased chemical synthesis of Corticosterone		 CTD PMID:15985365 PMID:21384875 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 EXP [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA; [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 protein; Clofibrate inhibits the reaction [Desoxycorticosterone results in increased expression of EDN1 protein]; Mibefradil inhibits the reaction [[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA]
Desoxycorticosterone results in increased expression of EDN1; Desoxycorticosterone results in increased expression of EDN1 protein		 CTD PMID:1860718 PMID:8934362 PMID:12600921 PMID:16054168 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A multiple interactions
affects response to substance		 EXP [5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Desoxycorticosterone results in increased chemical synthesis of Reactive Oxygen Species]; [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of EDNRA protein
EDNRA protein affects the susceptibility to Desoxycorticosterone		 CTD PMID:12600921 PMID:16271043 PMID:22431579 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Egf epidermal growth factor multiple interactions
increases response to substance		 EXP 4,5-dianilinophthalimide inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone]; RTKI cpd inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone] CTD PMID:11751714 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP Desoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter]; Desoxycorticosterone promotes the reaction [EP300 protein binds to TAT promoter] CTD PMID:22465009 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of FABP3 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of FABP3 protein] CTD PMID:21135038 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Gas6 growth arrest specific 6 multiple interactions EXP GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of IL6 protein]; GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of TNF protein] CTD PMID:19564549 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein] CTD PMID:22431579 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of HAVCR1 mRNA CTD PMID:21135038 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of IL1B mRNA CTD PMID:21135038 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 EXP Desoxycorticosterone results in increased expression of IL6 protein
GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of IL6 protein]		 CTD PMID:19564549 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of LCN2 mRNA; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of LCN2 mRNA] CTD PMID:21135038 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects localization EXP Desoxycorticosterone affects the localization of NCF1 protein CTD PMID:16271043 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nos3 nitric oxide synthase 3 decreases phosphorylation
multiple interactions
increases expression		 EXP Desoxycorticosterone results in decreased phosphorylation of NOS3 protein
NOS3 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]
Desoxycorticosterone results in increased expression of NOS3 protein		 CTD PMID:11834524 PMID:14993198 PMID:16271043 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of NOX1 protein CTD PMID:22431579 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nppa natriuretic peptide A increases expression EXP Desoxycorticosterone results in increased expression of NPPA protein CTD PMID:2965178 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases phosphorylation
multiple interactions
decreases expression		 ISO
EXP		 Desoxycorticosterone results in increased phosphorylation of NR3C1 protein
Desoxycorticosterone promotes the reaction [NR3C1 protein binds to TAT promoter]
Desoxycorticosterone results in decreased expression of NR3C1 mRNA
Desoxycorticosterone binds to and results in increased activity of NR3C1 protein		 CTD PMID:8969928 PMID:11956172 PMID:18483179 PMID:22465009 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression EXP Desoxycorticosterone results in decreased expression of NR3C2 mRNA CTD PMID:8969928 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP [PDGFA protein binds to PDGFB protein] which results in increased susceptibility to Desoxycorticosterone CTD PMID:11751714 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP [PDGFA protein binds to PDGFB protein] which results in increased susceptibility to Desoxycorticosterone CTD PMID:11751714 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pomc proopiomelanocortin increases abundance ISO POMC protein results in increased abundance of Desoxycorticosterone CTD PMID:3015796 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein affects the susceptibility to [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] CTD PMID:16054168 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Desoxycorticosterone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Desoxycorticosterone results in increased expression of PTGS2 protein CTD PMID:15834289 PMID:16271043 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of RAC1 protein CTD PMID:22431579 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Ren renin multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of REN protein CTD PMID:11039 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions EXP Desoxycorticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions EXP Desoxycorticosterone inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
multiple interactions		 EXP Desoxycorticosterone results in decreased expression of SOD1 protein
[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; tempol inhibits the reaction [Desoxycorticosterone results in decreased expression of SOD1 protein]		 CTD PMID:12646410 PMID:22431579 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression		 EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; Atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; SOD2 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]
Desoxycorticosterone results in decreased expression of SOD2 protein		 CTD PMID:11834524 PMID:22431579 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 mRNA; [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 mRNA] CTD PMID:21135038 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions EXP Desoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter] CTD PMID:22465009 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP Desoxycorticosterone promotes the reaction [EP300 protein binds to TAT promoter]; Desoxycorticosterone promotes the reaction [NR3C1 protein binds to TAT promoter] CTD PMID:22465009 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tnc tenascin C multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA]; Spironolactone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA] CTD PMID:21135038 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of TNF protein] CTD PMID:19564549 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein] CTD PMID:22431579 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression		 EXP NOS3 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]; SOD2 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein] CTD PMID:11834524 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions		 EXP Desoxycorticosterone results in increased activity of XDH protein
Desoxycorticosterone promotes the reaction [XDH protein results in increased chemical synthesis of Reactive Oxygen Species]		 CTD PMID:16271043 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      group 19775
        organic group 18905
          3-oxo-Delta(4)-steroid group 9162
            3-oxo-Delta(4) steroid 9162
              11-deoxycorticosterone 49
                11-deoxycorticosterone-21-hemisuccinate 0
                5alpha-dihydrodeoxycorticosterone 0
                5beta-dihydrodeoxycorticosterone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic group 18905
                              organic divalent group 18887
                                organodiyl group 18887
                                  carbonyl group 18853
                                    carbonyl compound 18853
                                      ketone 17140
                                        oxyketone 8803
                                          alpha-oxyketone 8803
                                            alpha-hydroxy ketone 8803
                                              primary alpha-hydroxy ketone 7680
                                                11-deoxycorticosterone 49
                                                  11-deoxycorticosterone-21-hemisuccinate 0
                                                  5alpha-dihydrodeoxycorticosterone 0
                                                  5beta-dihydrodeoxycorticosterone 0
paths to the root