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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzene-1,2,4-triol
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Accession:CHEBI:16971 term browser browse the term
Definition:A benzenetriol carrying hydroxy groups at positions 1, 2 and 4.
Synonyms:related_synonym: 1,2,4-Benzenetriol;   1,2,4-Trihydroxybenzene;   Formula=C6H6O3;   Hydroxyhydroquinone;   Hydroxyquinol;   InChI=1S/C6H6O3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9H;   InChIKey=GGNQRNBDZQJCCN-UHFFFAOYSA-N;   SMILES=Oc1ccc(O)c(O)c1
 alt_id: CHEBI:11136;   CHEBI:13877;   CHEBI:22709;   CHEBI:3026
 xref: CAS:533-73-3;   KEGG:C02814;   KNApSAcK:C00031480
 xref_mesh: MESH:C013038
 xref: MetaCyc:CPD-8130;   PDBeChem:HQN;   PMID:21396889;   PMID:24578277;   PMID:24803113;   UM-BBD_compID:c0264;   Wikipedia:Benzene-1\,2\,4-triol


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benzene-1,2,4-triol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO hydroxyhydroquinone results in increased expression of ABCC1 mRNA CTD PMID:17572062 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Acly ATP citrate lyase increases expression ISO hydroxyhydroquinone results in increased expression of ACLY mRNA CTD PMID:17572062 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Adsl adenylosuccinate lyase decreases expression ISO hydroxyhydroquinone results in decreased expression of ADSL mRNA CTD PMID:17572062 NCBI chr 7:122,157,201...122,192,328
Ensembl chr 7:122,157,201...122,192,328
JBrowse link
G Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 increases expression ISO hydroxyhydroquinone results in increased expression of AREL1 mRNA CTD PMID:17572062 NCBI chr 6:108,630,790...108,796,096
Ensembl chr 6:108,635,220...108,796,124
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 decreases expression ISO hydroxyhydroquinone results in decreased expression of ARL6IP5 mRNA CTD PMID:17572062 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of ATF3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of ATF3 mRNA]
CTD PMID:24530881 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO hydroxyhydroquinone results in increased expression of BACH1 mRNA CTD PMID:17572062 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BCL3 mRNA] CTD PMID:24530881 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BIRC3 mRNA] CTD PMID:24530881 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Casp3 caspase 3 increases activity ISO hydroxyhydroquinone results in increased activity of CASP3 protein CTD PMID:23776099 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases activity ISO hydroxyhydroquinone results in increased activity of CASP8 protein CTD PMID:23776099 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO hydroxyhydroquinone results in increased activity of CASP9 protein CTD PMID:23776099 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 affects expression ISO hydroxyhydroquinone affects the expression of CCL11 protein CTD PMID:17572062 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression ISO hydroxyhydroquinone affects the expression of CCL2 protein CTD PMID:17572062 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 affects expression ISO hydroxyhydroquinone affects the expression of CCL3 protein CTD PMID:17572062 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
increases expression
affects expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CCL4 mRNA]
hydroxyhydroquinone affects the expression of CCL4 protein
CTD PMID:17572062 PMID:24530881 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 affects expression ISO hydroxyhydroquinone affects the expression of CCL5 protein CTD PMID:17572062 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CHAC1 mRNA] CTD PMID:24530881 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroxyhydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO hydroxyhydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Cttn cortactin increases expression ISO hydroxyhydroquinone results in increased expression of CTTN mRNA CTD PMID:17572062 NCBI chr 1:217,602,698...217,638,196
NCBI chr 1:215,255,385...215,290,882
Ensembl chr 1:217,602,698...217,638,152
Ensembl chr 1:217,602,698...217,638,152
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL2 mRNA] CTD PMID:24530881 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroxyhydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:17572062 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO hydroxyhydroquinone results in increased expression of CYP27A1 mRNA CTD PMID:17572062 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone CTD PMID:15051535 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of DDIT4 mRNA] CTD PMID:24530881 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of DGAT2 mRNA] CTD PMID:24530881 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroxyhydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:17572062 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of EGR1 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of EGR1 mRNA]
CTD PMID:24530881 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO hydroxyhydroquinone results in decreased expression of EIF3A mRNA CTD PMID:17572062 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L decreases expression ISO hydroxyhydroquinone results in decreased expression of EIF3L mRNA CTD PMID:17572062 NCBI chr 7:120,320,547...120,331,596
Ensembl chr 7:120,320,547...120,331,595
JBrowse link
G Eng endoglin multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ENG mRNA] CTD PMID:24530881 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO hydroxyhydroquinone results in increased expression of ERO1A mRNA CTD PMID:17572062 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Eva1b eva-1 homolog B increases expression ISO hydroxyhydroquinone results in increased expression of EVA1B mRNA CTD PMID:17572062 NCBI chr 5:144,160,026...144,161,421
Ensembl chr 5:144,160,108...144,161,410
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO hydroxyhydroquinone results in increased expression of FAS protein CTD PMID:23776099 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO hydroxyhydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fdxr ferredoxin reductase increases expression ISO hydroxyhydroquinone results in increased expression of FDXR mRNA CTD PMID:17572062 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Gabpb2 GA binding protein transcription factor subunit beta 2 increases expression ISO hydroxyhydroquinone results in increased expression of GABPB2 mRNA CTD PMID:17572062 NCBI chr 2:196,357,030...196,392,514
Ensembl chr 2:196,359,243...196,377,883
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions
affects methylation
ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
hydroxyhydroquinone affects the methylation of GATA1 promoter
CTD PMID:21414390 PMID:30327826 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression
ISO hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroxyhydroquinone results in decreased expression of GATA2 mRNA
CTD PMID:21414390 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Gga1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 increases expression ISO hydroxyhydroquinone results in increased expression of GGA1 mRNA CTD PMID:17572062 NCBI chr 7:120,102,596...120,119,738
Ensembl chr 7:120,106,901...120,119,737
JBrowse link
G Gnaz G protein subunit alpha z increases expression ISO hydroxyhydroquinone results in increased expression of GNAZ mRNA CTD PMID:17572062 NCBI chr20:14,593,072...14,644,020
Ensembl chr20:14,593,819...14,620,019
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta increases expression ISO hydroxyhydroquinone results in increased expression of GP1BB mRNA CTD PMID:17572062 NCBI chr11:86,520,992...86,522,169
Ensembl chr11:86,520,992...86,522,169
JBrowse link
G Gypa glycophorin A decreases expression ISO hydroxyhydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr19:31,115,545...31,131,079 JBrowse link
G Hbb hemoglobin subunit beta multiple interactions ISO Decitabine inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; trichostatin A inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]] CTD PMID:21414390 PMID:30327826 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression ISO hydroxyhydroquinone results in increased expression of HES1 mRNA CTD PMID:17572062 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l increases expression ISO hydroxyhydroquinone results in increased expression of H2BC8 mRNA CTD PMID:17572062 NCBI chr17:44,748,445...44,748,910
Ensembl chr17:44,748,482...44,748,862
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 increases expression ISO hydroxyhydroquinone results in increased expression of H2AC18 mRNA CTD PMID:17572062 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:24530881 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO hydroxyhydroquinone results in increased expression of HSP90AA1 mRNA CTD PMID:17572062 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO hydroxyhydroquinone results in increased expression of HSPA1A mRNA CTD PMID:17572062 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO hydroxyhydroquinone results in increased expression of HSPA1B mRNA CTD PMID:17572062 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Ifng interferon gamma multiple interactions ISO [IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide]; Lipopolysaccharides promotes the reaction [[IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 multiple interactions ISO hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein] CTD PMID:17572062 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il6 interleukin 6 increases expression ISO hydroxyhydroquinone results in increased expression of IL6 protein CTD PMID:17572062 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itga2b integrin subunit alpha 2b increases expression ISO hydroxyhydroquinone results in increased expression of ITGA2B mRNA CTD PMID:17572062 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO hydroxyhydroquinone results in increased expression of ITGB3 mRNA CTD PMID:17572062 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 increases expression ISO hydroxyhydroquinone results in increased expression of JARID2 mRNA CTD PMID:17572062 NCBI chr17:20,183,440...20,365,219
Ensembl chr17:20,184,245...20,364,714
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of JUN mRNA] CTD PMID:24530881 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnd1 potassium voltage-gated channel subfamily D member 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of KCND1 mRNA CTD PMID:17572062 NCBI chr  X:15,506,724...15,520,712
Ensembl chr  X:15,506,724...15,520,712
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO hydroxyhydroquinone results in increased expression of KEAP1 mRNA CTD PMID:17572062 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Klf2 Kruppel-like factor 2 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLF2 mRNA] CTD PMID:24530881 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klhdc7b kelch domain containing 7B increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of KLHDC7B mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLHDC7B mRNA]
CTD PMID:24530881 NCBI chr 7:130,357,589...130,359,529
Ensembl chr 7:130,357,643...130,359,448
JBrowse link
G Lingo3 leucine rich repeat and Ig domain containing 3 decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of LINGO3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of LINGO3 mRNA]
CTD PMID:24530881 NCBI chr 7:11,737,293...11,746,703
Ensembl chr 7:11,737,293...11,746,703
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANOS1 mRNA] CTD PMID:24530881 NCBI chr 1:282,134,676...282,140,370
Ensembl chr 1:282,134,981...282,135,772
JBrowse link
G Nanp N-acetylneuraminic acid phosphatase multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANP mRNA] CTD PMID:24530881 NCBI chr 3:146,800,018...146,812,988
Ensembl chr 3:146,800,019...146,812,989
JBrowse link
G Nck2 NCK adaptor protein 2 increases expression ISO hydroxyhydroquinone results in increased expression of NCK2 mRNA CTD PMID:17572062 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroxyhydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 1:164,803,574...164,814,777
Ensembl chr 1:164,803,574...164,814,651
JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr 7:144,872,739...144,880,092
Ensembl chr 7:144,872,747...144,880,092
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of NFKBIA mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of NFKBIA mRNA]
CTD PMID:24530881 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Pde11a phosphodiesterase 11A multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PDE11A mRNA] CTD PMID:24530881 NCBI chr 3:62,818,502...63,211,843
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO hydroxyhydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:17572062 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Plin2 perilipin 2 increases expression ISO hydroxyhydroquinone results in increased expression of PLIN2 mRNA CTD PMID:17572062 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Polr1g RNA polymerase I subunit G multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of POLR1G mRNA] CTD PMID:24530881 NCBI chr 1:80,267,725...80,271,001
Ensembl chr 1:80,267,725...80,271,001
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases expression ISO hydroxyhydroquinone results in increased expression of PPP1R12A mRNA CTD PMID:17572062 NCBI chr 7:51,404,971...51,515,382
Ensembl chr 7:51,404,919...51,515,373
JBrowse link
G Prdm12 PR/SET domain 12 decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of PRDM12 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRDM12 mRNA]
CTD PMID:24530881 NCBI chr 3:10,181,104...10,199,185
Ensembl chr 3:10,181,924...10,196,626
JBrowse link
G Prtn3 proteinase 3 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRTN3 mRNA] CTD PMID:24530881 NCBI chr 7:12,643,712...12,646,951
Ensembl chr 7:12,643,516...12,646,960
JBrowse link
G Prune1 prune exopolyphosphatase 1 increases expression ISO hydroxyhydroquinone results in increased expression of PRUNE1 mRNA CTD PMID:17572062 NCBI chr 2:196,427,714...196,457,105
Ensembl chr 2:196,427,710...196,456,481
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of PTPN3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PTPN3 mRNA]
CTD PMID:24530881 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
G Rab22a RAB22A, member RAS oncogene family increases expression ISO hydroxyhydroquinone results in increased expression of RAB22A mRNA CTD PMID:17572062 NCBI chr 3:171,743,884...171,790,558
Ensembl chr 3:171,743,929...171,790,558
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of RELB mRNA] CTD PMID:24530881 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rilp Rab interacting lysosomal protein decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of RILP mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RILP mRNA]
CTD PMID:24530881 NCBI chr10:63,658,451...63,662,428
Ensembl chr10:63,659,085...63,662,050
JBrowse link
G Rpl15 ribosomal protein L15 decreases expression ISO hydroxyhydroquinone results in decreased expression of RPL15 mRNA CTD PMID:17572062 NCBI chr15:8,188,717...8,192,153
Ensembl chr15:8,189,253...8,192,152
JBrowse link
G Rpl5 ribosomal protein L5 decreases expression ISO hydroxyhydroquinone results in decreased expression of RPL5 mRNA CTD PMID:17572062 NCBI chr14:2,860,963...2,867,397
Ensembl chr14:2,860,965...2,867,397
JBrowse link
G RT1-Ha RT1 class II, locus Ha decreases expression ISO hydroxyhydroquinone results in decreased expression of HLA-DPA1 mRNA CTD PMID:17572062 NCBI chr20:3,875,478...3,885,140
Ensembl chr20:3,875,706...3,881,461
JBrowse link
G Rtn4r reticulon 4 receptor decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of RTN4R mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RTN4R mRNA]
CTD PMID:24530881 NCBI chr11:86,992,665...87,017,091
Ensembl chr11:86,992,399...87,017,115
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of SCIMP mRNA] CTD PMID:24530881 NCBI chr10:57,415,429...57,436,412
Ensembl chr10:57,415,832...57,436,368
JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of SERPINF1 mRNA CTD PMID:17572062 NCBI chr10:62,241,750...62,254,145
Ensembl chr10:62,241,756...62,254,287
JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of SESN2 mRNA] CTD PMID:24530881 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 increases expression ISO hydroxyhydroquinone results in increased expression of SH3BP2 mRNA CTD PMID:17572062 NCBI chr14:81,435,445...81,473,013
Ensembl chr14:81,435,449...81,472,952
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of SORL1 mRNA CTD PMID:17572062 NCBI chr 8:46,228,077...46,287,171 JBrowse link
G Srsf9 serine and arginine rich splicing factor 9 decreases expression ISO hydroxyhydroquinone results in decreased expression of SRSF9 mRNA CTD PMID:17572062 NCBI chr12:47,039,714...47,046,022
Ensembl chr12:47,039,716...47,046,022
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO hydroxyhydroquinone results in decreased expression of ST3GAL3 mRNA CTD PMID:23776099 NCBI chr 5:136,765,309...136,965,642
Ensembl chr 5:136,766,208...136,965,191
JBrowse link
G Steap3 STEAP3 metalloreductase multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of STEAP3 mRNA] CTD PMID:24530881 NCBI chr13:36,257,220...36,274,144
Ensembl chr13:36,257,112...36,290,531
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of TFRC protein
hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of TFRC mRNA]
CTD PMID:21414390 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TLR9 mRNA] CTD PMID:24530881 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tmem158 transmembrane protein 158 increases expression ISO hydroxyhydroquinone results in increased expression of TMEM158 mRNA CTD PMID:17572062 NCBI chr 8:132,344,710...132,345,708
Ensembl chr 8:132,344,710...132,345,708
JBrowse link
G Tnf tumor necrosis factor increases expression ISO hydroxyhydroquinone results in increased expression of TNF mRNA CTD PMID:17572062 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of TNFAIP6 mRNA] CTD PMID:24530881 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TNFRSF8 mRNA] CTD PMID:24530881 NCBI chr 5:163,186,349...163,231,578
Ensembl chr 5:163,186,349...163,231,578
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO hydroxyhydroquinone results in decreased activity of TOP2A protein CTD PMID:7586126 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Ttll4 tubulin tyrosine ligase like 4 increases expression ISO hydroxyhydroquinone results in increased expression of TTLL4 mRNA CTD PMID:17572062 NCBI chr 9:81,925,363...81,961,882
Ensembl chr 9:81,940,630...81,954,686
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO hydroxyhydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:17572062 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ZBTB42 mRNA] CTD PMID:24530881 NCBI chr 6:137,238,899...137,247,115
Ensembl chr 6:137,243,185...137,245,313
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    chemical entity 19875
      molecular entity 19872
        polyatomic entity 19786
          heteroatomic molecular entity 19711
            hydroxides 19139
              organic hydroxy compound 18694
                phenols 18176
                  benzenetriol 2551
                    benzene-1,2,4-triol 105
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      chalcogen 19454
                        oxygen atom 19415
                          oxygen molecular entity 19415
                            hydroxides 19139
                              organic hydroxy compound 18694
                                polyol 7826
                                  triol 5987
                                    benzenetriol 2551
                                      benzene-1,2,4-triol 105
paths to the root