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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzene-1,2,4-triol
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Accession:CHEBI:16971 term browser browse the term
Definition:A benzenetriol carrying hydroxy groups at positions 1, 2 and 4.
Synonyms:related_synonym: 1,2,4-Benzenetriol;   1,2,4-Trihydroxybenzene;   Formula=C6H6O3;   Hydroxyhydroquinone;   Hydroxyquinol;   InChI=1S/C6H6O3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9H;   InChIKey=GGNQRNBDZQJCCN-UHFFFAOYSA-N;   SMILES=Oc1ccc(O)c(O)c1
 alt_id: CHEBI:11136;   CHEBI:13877;   CHEBI:22709;   CHEBI:3026
 xref: CAS:533-73-3;   KEGG:C02814;   KNApSAcK:C00031480
 xref_mesh: MESH:C013038
 xref: MetaCyc:CPD-8130;   PDBeChem:HQN;   PMID:21396889;   PMID:24578277;   PMID:24803113;   UM-BBD_compID:c0264;   Wikipedia:Benzene-1\,2\,4-triol


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benzene-1,2,4-triol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 increases expression ISO hydroxyhydroquinone results in increased expression of ABCC1 mRNA CTD PMID:17572062 NCBI chr16:14,361,453...14,474,878
Ensembl chr16:14,361,558...14,475,737
JBrowse link
G Acly ATP citrate lyase increases expression ISO hydroxyhydroquinone results in increased expression of ACLY mRNA CTD PMID:17572062 NCBI chr11:100,476,352...100,528,000
Ensembl chr11:100,476,353...100,528,000
JBrowse link
G Adsl adenylosuccinate lyase decreases expression ISO hydroxyhydroquinone results in decreased expression of ADSL mRNA CTD PMID:17572062 NCBI chr15:80,948,490...80,970,947
Ensembl chr15:80,948,490...80,970,946
JBrowse link
G Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 increases expression ISO hydroxyhydroquinone results in increased expression of AREL1 mRNA CTD PMID:17572062 NCBI chr12:84,918,140...84,970,878
Ensembl chr12:84,918,148...84,970,900
JBrowse link
G Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 decreases expression ISO hydroxyhydroquinone results in decreased expression of ARL6IP5 mRNA CTD PMID:17572062 NCBI chr 6:97,210,792...97,233,315
Ensembl chr 6:97,210,689...97,233,315
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of ATF3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of ATF3 mRNA]
CTD PMID:24530881 NCBI chr 1:191,170,296...191,183,333
Ensembl chr 1:191,170,296...191,218,039
JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 increases expression ISO hydroxyhydroquinone results in increased expression of BACH1 mRNA CTD PMID:17572062 NCBI chr16:87,698,954...87,733,346
Ensembl chr16:87,698,945...87,733,346
JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BCL3 mRNA] CTD PMID:24530881 NCBI chr 7:19,808,462...19,822,824
Ensembl chr 7:19,808,462...19,822,770
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BIRC3 mRNA] CTD PMID:24530881 NCBI chr 9:7,847,468...7,873,205
Ensembl chr 9:7,848,699...7,873,186
JBrowse link
G Casp3 caspase 3 increases activity ISO hydroxyhydroquinone results in increased activity of CASP3 protein CTD PMID:23776099 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp8 caspase 8 increases activity ISO hydroxyhydroquinone results in increased activity of CASP8 protein CTD PMID:23776099 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Casp9 caspase 9 increases activity ISO hydroxyhydroquinone results in increased activity of CASP9 protein CTD PMID:23776099 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Ccl11 chemokine (C-C motif) ligand 11 affects expression ISO hydroxyhydroquinone affects the expression of CCL11 protein CTD PMID:17572062 NCBI chr11:82,057,832...82,062,955
Ensembl chr11:82,057,823...82,062,955
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 affects expression ISO hydroxyhydroquinone affects the expression of CCL2 protein CTD PMID:17572062 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl3 chemokine (C-C motif) ligand 3 affects expression ISO hydroxyhydroquinone affects the expression of CCL3 protein CTD PMID:17572062 NCBI chr11:83,647,843...83,649,378
Ensembl chr11:83,647,844...83,649,355
JBrowse link
G Ccl4 chemokine (C-C motif) ligand 4 multiple interactions
increases expression
affects expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CCL4 mRNA]
hydroxyhydroquinone affects the expression of CCL4 protein
CTD PMID:17572062 PMID:24530881 NCBI chr11:83,648,624...83,664,683
Ensembl chr11:83,662,584...83,664,683
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 affects expression ISO hydroxyhydroquinone affects the expression of CCL5 protein CTD PMID:17572062 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Cd3eap CD3E antigen, epsilon polypeptide associated protein multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of POLR1G mRNA] CTD PMID:24530881 NCBI chr 7:19,356,007...19,359,483
Ensembl chr 7:19,356,014...19,359,483
JBrowse link
G Chac1 ChaC, cation transport regulator 1 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CHAC1 mRNA] CTD PMID:24530881 NCBI chr 2:119,351,242...119,354,326
Ensembl chr 2:119,351,229...119,354,381
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO hydroxyhydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr18:61,105,572...61,131,139
Ensembl chr18:61,100,598...61,132,149
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions EXP hydroxyhydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Cttn cortactin increases expression ISO hydroxyhydroquinone results in increased expression of CTTN mRNA CTD PMID:17572062 NCBI chr 7:144,435,724...144,471,560
Ensembl chr 7:144,435,733...144,471,009
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 affects expression
increases expression
multiple interactions
ISO hydroxyhydroquinone affects the expression of CXCL8 protein
hydroxyhydroquinone results in increased expression of CXCL8 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL8 mRNA]
CTD PMID:17572062 PMID:24530881 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcl2 chemokine (C-X-C motif) ligand 2 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL2 mRNA] CTD PMID:24530881 NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO hydroxyhydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:17572062 NCBI chr17:79,706,940...79,715,061
Ensembl chr17:79,701,537...79,715,061
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO hydroxyhydroquinone results in increased expression of CYP27A1 mRNA CTD PMID:17572062 NCBI chr 1:74,713,148...74,737,897
Ensembl chr 1:74,713,574...74,737,892
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone CTD PMID:15051535 NCBI chr 7:140,763,819...140,774,990
Ensembl chr 7:140,763,739...140,774,987
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of DDIT4 mRNA] CTD PMID:24530881 NCBI chr10:59,949,675...59,951,770
Ensembl chr10:59,949,669...59,951,834
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of DGAT2 mRNA] CTD PMID:24530881 NCBI chr 7:99,153,663...99,182,713
Ensembl chr 7:99,153,658...99,182,719
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO hydroxyhydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:17572062 NCBI chr 8:83,608,175...83,612,653
Ensembl chr 8:83,608,193...83,612,653
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of EGR1 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of EGR1 mRNA]
CTD PMID:24530881 NCBI chr18:34,861,207...34,864,956
Ensembl chr18:34,859,823...34,864,984
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO hydroxyhydroquinone results in decreased expression of EIF3A mRNA CTD PMID:17572062 NCBI chr19:60,761,116...60,790,693
Ensembl chr19:60,761,117...60,790,658
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L decreases expression ISO hydroxyhydroquinone results in decreased expression of EIF3L mRNA CTD PMID:17572062 NCBI chr15:79,075,223...79,094,400
Ensembl chr15:79,075,179...79,094,405
JBrowse link
G Eng endoglin multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ENG mRNA] CTD PMID:24530881 NCBI chr 2:32,646,595...32,682,669
Ensembl chr 2:32,646,595...32,682,669
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO hydroxyhydroquinone results in increased expression of ERO1A mRNA CTD PMID:17572062 NCBI chr14:45,283,087...45,318,572
Ensembl chr14:45,283,087...45,318,771
JBrowse link
G Eva1b eva-1 homolog B (C. elegans) increases expression ISO hydroxyhydroquinone results in increased expression of EVA1B mRNA CTD PMID:17572062 NCBI chr 4:126,145,709...126,149,875
Ensembl chr 4:126,147,744...126,149,875
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) increases expression ISO hydroxyhydroquinone results in increased expression of FAS protein CTD PMID:23776099 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) increases expression ISO hydroxyhydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fdxr ferredoxin reductase increases expression ISO hydroxyhydroquinone results in increased expression of FDXR mRNA CTD PMID:17572062 NCBI chr11:115,268,024...115,277,101
Ensembl chr11:115,268,024...115,277,050
JBrowse link
G Gabpb2 GA repeat binding protein, beta 2 increases expression ISO hydroxyhydroquinone results in increased expression of GABPB2 mRNA CTD PMID:17572062 NCBI chr 3:95,181,766...95,218,110
Ensembl chr 3:95,181,766...95,217,916
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions
affects methylation
ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
hydroxyhydroquinone affects the methylation of GATA1 promoter
CTD PMID:21414390 PMID:30327826 NCBI chr  X:7,959,260...7,976,663
Ensembl chr  X:7,959,260...7,978,071
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions
decreases expression
ISO hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroxyhydroquinone results in decreased expression of GATA2 mRNA
CTD PMID:21414390 NCBI chr 6:88,193,891...88,207,032
Ensembl chr 6:88,193,891...88,207,032
JBrowse link
G Gga1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 increases expression ISO hydroxyhydroquinone results in increased expression of GGA1 mRNA CTD PMID:17572062 NCBI chr15:78,877,167...78,894,585
Ensembl chr15:78,877,190...78,894,585
JBrowse link
G Gnaz guanine nucleotide binding protein, alpha z subunit increases expression ISO hydroxyhydroquinone results in increased expression of GNAZ mRNA CTD PMID:17572062 NCBI chr10:74,967,177...75,016,907
Ensembl chr10:74,967,177...75,016,907
JBrowse link
G Gp1bb glycoprotein Ib, beta polypeptide increases expression ISO hydroxyhydroquinone results in increased expression of GP1BB mRNA CTD PMID:17572062 NCBI chr16:18,620,319...18,622,403
Ensembl chr16:18,620,317...18,622,403
JBrowse link
G Gypa glycophorin A decreases expression ISO hydroxyhydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr 8:80,494,045...80,510,785
Ensembl chr 8:80,493,781...80,510,542
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus decreases expression ISO hydroxyhydroquinone results in decreased expression of HLA-DPA1 mRNA CTD PMID:17572062 NCBI chr17:34,084,613...34,085,852
Ensembl chr17:34,084,601...34,085,823
JBrowse link
G H2ac18 H2A clustered histone 18 increases expression ISO hydroxyhydroquinone results in increased expression of H2AC18 mRNA CTD PMID:17572062 NCBI chr 3:96,245,497...96,246,052
Ensembl chr 3:96,245,497...96,246,082
JBrowse link
G H2bc8 H2B clustered histone 8 increases expression ISO hydroxyhydroquinone results in increased expression of H2BC8 mRNA CTD PMID:17572062 NCBI chr13:23,571,400...23,571,863
Ensembl chr13:23,571,396...23,572,013
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain multiple interactions ISO Decitabine inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; trichostatin A inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]] CTD PMID:21414390 PMID:30327826
G Hes1 hes family bHLH transcription factor 1 increases expression ISO hydroxyhydroquinone results in increased expression of HES1 mRNA CTD PMID:17572062 NCBI chr16:30,065,357...30,067,796
Ensembl chr16:30,064,384...30,067,796
JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 NCBI chr 9:44,336,348...44,344,228
Ensembl chr 9:44,336,339...44,344,228
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:24530881 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 increases expression ISO hydroxyhydroquinone results in increased expression of HSP90AA1 mRNA CTD PMID:17572062 NCBI chr12:110,691,036...110,696,395
Ensembl chr12:110,690,605...110,702,728
JBrowse link
G Hspa1a heat shock protein 1A increases expression ISO hydroxyhydroquinone results in increased expression of HSPA1A mRNA CTD PMID:17572062 NCBI chr17:34,969,359...34,972,156
Ensembl chr17:34,969,190...34,972,156
JBrowse link
G Hspa1b heat shock protein 1B increases expression ISO hydroxyhydroquinone results in increased expression of HSPA1B mRNA CTD PMID:17572062 NCBI chr17:34,956,429...34,959,238
Ensembl chr17:34,956,436...34,959,238
JBrowse link
G Ifng interferon gamma multiple interactions EXP [IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide]; Lipopolysaccharides promotes the reaction [[IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il10 interleukin 10 multiple interactions ISO hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein] CTD PMID:17572062 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il6 interleukin 6 increases expression ISO hydroxyhydroquinone results in increased expression of IL6 protein CTD PMID:17572062 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itga2b integrin alpha 2b increases expression ISO hydroxyhydroquinone results in increased expression of ITGA2B mRNA CTD PMID:17572062 NCBI chr11:102,453,297...102,469,883
Ensembl chr11:102,453,297...102,470,122
JBrowse link
G Itgb3 integrin beta 3 increases expression ISO hydroxyhydroquinone results in increased expression of ITGB3 mRNA CTD PMID:17572062 NCBI chr11:104,608,000...104,670,476
Ensembl chr11:104,608,000...104,670,476
JBrowse link
G Jarid2 jumonji, AT rich interactive domain 2 increases expression ISO hydroxyhydroquinone results in increased expression of JARID2 mRNA CTD PMID:17572062 NCBI chr13:44,730,774...44,921,643
Ensembl chr13:44,729,474...44,921,643
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of JUN mRNA] CTD PMID:24530881 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kcnd1 potassium voltage-gated channel, Shal-related family, member 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of KCND1 mRNA CTD PMID:17572062 NCBI chr  X:7,823,759...7,838,278
Ensembl chr  X:7,822,289...7,838,280
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 increases expression ISO hydroxyhydroquinone results in increased expression of KEAP1 mRNA CTD PMID:17572062 NCBI chr 9:21,229,730...21,239,332
Ensembl chr 9:21,229,730...21,239,361
JBrowse link
G Klf2 Kruppel-like factor 2 (lung) multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLF2 mRNA] CTD PMID:24530881 NCBI chr 8:72,319,062...72,321,654
Ensembl chr 8:72,319,033...72,321,656
JBrowse link
G Klhdc7b kelch domain containing 7B increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of KLHDC7B mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLHDC7B mRNA]
CTD PMID:24530881 NCBI chr15:89,384,059...89,389,822
Ensembl chr15:89,384,917...89,388,867
JBrowse link
G Lingo3 leucine rich repeat and Ig domain containing 3 decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of LINGO3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of LINGO3 mRNA]
CTD PMID:24530881 NCBI chr10:80,832,801...80,844,039
Ensembl chr10:80,832,801...80,844,039
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANOS1 mRNA] CTD PMID:24530881 NCBI chr19:60,755,987...60,759,914
Ensembl chr19:60,755,987...60,759,914
JBrowse link
G Nanp N-acetylneuraminic acid phosphatase multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANP mRNA] CTD PMID:24530881 NCBI chr 2:151,029,685...151,039,379
Ensembl chr 2:151,029,685...151,039,398
JBrowse link
G Nck2 non-catalytic region of tyrosine kinase adaptor protein 2 increases expression ISO hydroxyhydroquinone results in increased expression of NCK2 mRNA CTD PMID:17572062 NCBI chr 1:43,445,483...43,570,518
Ensembl chr 1:43,444,579...43,570,515
JBrowse link
G Neu3 neuraminidase 3 increases expression ISO hydroxyhydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr 7:99,811,434...99,828,457
Ensembl chr 7:99,811,439...99,828,417
JBrowse link
G Nfe2 nuclear factor, erythroid derived 2 multiple interactions ISO hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr15:103,248,212...103,258,403
Ensembl chr15:103,248,212...103,258,403
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases expression
multiple interactions
ISO hydroxyhydroquinone results in increased expression of NFKBIA mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of NFKBIA mRNA]
CTD PMID:24530881 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Pde11a phosphodiesterase 11A multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PDE11A mRNA] CTD PMID:24530881 NCBI chr 2:75,985,808...76,339,145
Ensembl chr 2:75,989,141...76,338,774
JBrowse link
G Phlda1 pleckstrin homology like domain, family A, member 1 increases expression ISO hydroxyhydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:17572062 NCBI chr10:111,506,286...111,508,649
Ensembl chr10:111,506,286...111,508,645
JBrowse link
G Plin2 perilipin 2 increases expression ISO hydroxyhydroquinone results in increased expression of PLIN2 mRNA CTD PMID:17572062 NCBI chr 4:86,626,910...86,670,217
Ensembl chr 4:86,648,386...86,670,060
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases expression ISO hydroxyhydroquinone results in increased expression of PPP1R12A mRNA CTD PMID:17572062 NCBI chr10:108,162,092...108,279,985
Ensembl chr10:108,162,193...108,284,475
JBrowse link
G Prdm12 PR domain containing 12 decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of PRDM12 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRDM12 mRNA]
CTD PMID:24530881 NCBI chr 2:31,635,026...31,655,795
Ensembl chr 2:31,640,037...31,655,795
JBrowse link
G Prtn3 proteinase 3 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRTN3 mRNA] CTD PMID:24530881 NCBI chr10:79,879,667...79,883,174
Ensembl chr10:79,874,476...79,883,174
JBrowse link
G Prune1 prune exopolyphosphatase increases expression ISO hydroxyhydroquinone results in increased expression of PRUNE1 mRNA CTD PMID:17572062 NCBI chr 3:95,253,674...95,283,506
Ensembl chr 3:95,253,674...95,282,076
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of PTPN3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PTPN3 mRNA]
CTD PMID:24530881 NCBI chr 4:57,190,841...57,339,040
Ensembl chr 4:57,190,841...57,301,837
JBrowse link
G Rab22a RAB22A, member RAS oncogene family increases expression ISO hydroxyhydroquinone results in increased expression of RAB22A mRNA CTD PMID:17572062 NCBI chr 2:173,659,836...173,702,186
Ensembl chr 2:173,659,760...173,707,343
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of RELB mRNA] CTD PMID:24530881 NCBI chr 7:19,606,217...19,629,438
Ensembl chr 7:19,606,217...19,629,438
JBrowse link
G Rilp Rab interacting lysosomal protein decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of RILP mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RILP mRNA]
CTD PMID:24530881 NCBI chr11:75,510,094...75,513,168
Ensembl chr11:75,510,094...75,513,168
JBrowse link
G Rpl15 ribosomal protein L15 decreases expression ISO hydroxyhydroquinone results in decreased expression of RPL15 mRNA CTD PMID:17572062 NCBI chr14:18,267,823...18,270,986
Ensembl chr14:18,267,823...18,271,391
JBrowse link
G Rpl5 ribosomal protein L5 decreases expression ISO hydroxyhydroquinone results in decreased expression of RPL5 mRNA CTD PMID:17572062 NCBI chr 5:107,900,508...107,909,005
Ensembl chr 5:107,900,502...107,909,005
JBrowse link
G Rtn4r reticulon 4 receptor decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of RTN4R mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RTN4R mRNA]
CTD PMID:24530881 NCBI chr16:18,127,642...18,152,408
Ensembl chr16:18,127,642...18,152,408
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of SCIMP mRNA] CTD PMID:24530881 NCBI chr11:70,790,932...70,812,561
Ensembl chr11:70,790,932...70,812,586
JBrowse link
G Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 decreases expression ISO hydroxyhydroquinone results in decreased expression of SERPINF1 mRNA CTD PMID:17572062 NCBI chr11:75,410,029...75,422,623
Ensembl chr11:75,409,769...75,422,701
JBrowse link
G Sesn2 sestrin 2 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of SESN2 mRNA] CTD PMID:24530881 NCBI chr 4:132,492,804...132,510,456
Ensembl chr 4:132,492,032...132,510,501
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 increases expression ISO hydroxyhydroquinone results in increased expression of SH3BP2 mRNA CTD PMID:17572062 NCBI chr 5:34,525,784...34,563,639
Ensembl chr 5:34,525,838...34,563,641
JBrowse link
G Sorl1 sortilin-related receptor, LDLR class A repeats-containing decreases expression ISO hydroxyhydroquinone results in decreased expression of SORL1 mRNA CTD PMID:17572062 NCBI chr 9:41,964,709...42,124,297
Ensembl chr 9:41,964,720...42,124,297
JBrowse link
G Srsf9 serine and arginine-rich splicing factor 9 decreases expression ISO hydroxyhydroquinone results in decreased expression of SRSF9 mRNA CTD PMID:17572062 NCBI chr 5:115,327,163...115,333,843
Ensembl chr 5:115,327,177...115,333,080
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression ISO hydroxyhydroquinone results in decreased expression of ST3GAL3 mRNA CTD PMID:23776099 NCBI chr 4:117,932,152...118,134,972
Ensembl chr 4:117,932,154...118,134,914
JBrowse link
G Steap3 STEAP family member 3 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of STEAP3 mRNA] CTD PMID:24530881 NCBI chr 1:120,226,414...120,271,081
Ensembl chr 1:120,190,757...120,272,705
JBrowse link
G Tfrc transferrin receptor decreases expression
multiple interactions
ISO hydroxyhydroquinone results in decreased expression of TFRC protein
hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of TFRC mRNA]
CTD PMID:21414390 NCBI chr16:32,608,896...32,632,794
Ensembl chr16:32,608,920...32,632,794
JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TLR9 mRNA] CTD PMID:24530881 NCBI chr 9:106,222,598...106,226,876
Ensembl chr 9:106,222,598...106,226,883
JBrowse link
G Tmem158 transmembrane protein 158 increases expression ISO hydroxyhydroquinone results in increased expression of TMEM158 mRNA CTD PMID:17572062 NCBI chr 9:123,259,057...123,260,789
Ensembl chr 9:123,259,053...123,260,764
JBrowse link
G Tnf tumor necrosis factor increases expression ISO hydroxyhydroquinone results in increased expression of TNF mRNA CTD PMID:17572062 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 multiple interactions
increases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of TNFAIP6 mRNA] CTD PMID:24530881 NCBI chr 2:52,038,113...52,056,681
Ensembl chr 2:52,038,009...52,056,686
JBrowse link
G Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TNFRSF8 mRNA] CTD PMID:24530881 NCBI chr 4:145,267,132...145,315,164
Ensembl chr 4:145,267,137...145,315,164
JBrowse link
G Top2a topoisomerase (DNA) II alpha decreases activity ISO hydroxyhydroquinone results in decreased activity of TOP2A protein CTD PMID:7586126 NCBI chr11:98,992,947...99,024,199
Ensembl chr11:98,992,943...99,024,189
JBrowse link
G Ttll4 tubulin tyrosine ligase-like family, member 4 increases expression ISO hydroxyhydroquinone results in increased expression of TTLL4 mRNA CTD PMID:17572062 NCBI chr 1:74,661,645...74,701,832
Ensembl chr 1:74,661,745...74,703,730
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO hydroxyhydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:17572062 NCBI chr10:82,833,951...82,897,724
Ensembl chr10:82,833,951...82,897,712
JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions
decreases expression
ISO 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ZBTB42 mRNA] CTD PMID:24530881 NCBI chr12:112,678,648...112,682,747
Ensembl chr12:112,678,828...112,682,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21552
    chemical entity 21550
      molecular entity 21534
        polyatomic entity 21410
          heteroatomic molecular entity 21336
            hydroxides 20130
              organic hydroxy compound 19164
                phenols 18461
                  benzenetriol 2607
                    benzene-1,2,4-triol 106
Path 2
Term Annotations click to browse term
  CHEBI ontology 21552
    subatomic particle 21537
      composite particle 21537
        hadron 21537
          baryon 21537
            nucleon 21537
              atomic nucleus 21537
                atom 21537
                  main group element atom 21442
                    p-block element atom 21442
                      chalcogen 20515
                        oxygen atom 20492
                          oxygen molecular entity 20492
                            hydroxides 20130
                              organic hydroxy compound 19164
                                polyol 7904
                                  triol 6070
                                    benzenetriol 2607
                                      benzene-1,2,4-triol 106
paths to the root