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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzene-1,2,4-triol
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Accession:CHEBI:16971 term browser browse the term
Definition:A benzenetriol carrying hydroxy groups at positions 1, 2 and 4.
Synonyms:related_synonym: 1,2,4-Benzenetriol;   1,2,4-Trihydroxybenzene;   Formula=C6H6O3;   Hydroxyhydroquinone;   Hydroxyquinol;   InChI=1S/C6H6O3/c7-4-1-2-5(8)6(9)3-4/h1-3,7-9H;   InChIKey=GGNQRNBDZQJCCN-UHFFFAOYSA-N;   SMILES=Oc1ccc(O)c(O)c1
 alt_id: CHEBI:11136;   CHEBI:13877;   CHEBI:22709;   CHEBI:3026
 xref: CAS:533-73-3;   KEGG:C02814;   KNApSAcK:C00031480
 xref_mesh: MESH:C013038
 xref: MetaCyc:CPD-8130;   PDBeChem:HQN;   PMID:21396889;   PMID:24578277;   PMID:24803113;   UM-BBD_compID:c0264;   Wikipedia:Benzene-1\,2\,4-triol


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benzene-1,2,4-triol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 increases expression EXP hydroxyhydroquinone results in increased expression of ABCC1 mRNA CTD PMID:17572062 NCBI chr16:15,949,616...16,143,062
Ensembl chr16:15,949,577...16,143,074
Ensembl chr16:15,949,577...16,143,074
JBrowse link
G ACLY ATP citrate lyase increases expression EXP hydroxyhydroquinone results in increased expression of ACLY mRNA CTD PMID:17572062 NCBI chr17:41,866,916...41,930,542
Ensembl chr17:41,866,917...41,930,542
JBrowse link
G ADSL adenylosuccinate lyase decreases expression EXP hydroxyhydroquinone results in decreased expression of ADSL mRNA CTD PMID:17572062 NCBI chr22:40,346,500...40,387,527
Ensembl chr22:40,346,500...40,390,463
JBrowse link
G ANKRD19P ankyrin repeat domain 19, pseudogene multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ANKRD19P mRNA] CTD PMID:24530881 NCBI chr 9:92,809,611...92,838,457
Ensembl chr 9:92,809,568...92,838,457
JBrowse link
G AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 increases expression EXP hydroxyhydroquinone results in increased expression of AREL1 mRNA CTD PMID:17572062 NCBI chr14:74,661,256...74,713,118
Ensembl chr14:74,653,437...74,713,108
JBrowse link
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 decreases expression EXP hydroxyhydroquinone results in decreased expression of ARL6IP5 mRNA CTD PMID:17572062 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092
JBrowse link
G ATF3 activating transcription factor 3 increases expression
multiple interactions
EXP hydroxyhydroquinone results in increased expression of ATF3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of ATF3 mRNA]
CTD PMID:24530881 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G BACH1 BTB domain and CNC homolog 1 increases expression EXP hydroxyhydroquinone results in increased expression of BACH1 mRNA CTD PMID:17572062 NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751
JBrowse link
G BCL3 BCL3 transcription coactivator multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BCL3 mRNA] CTD PMID:24530881 NCBI chr19:44,742,620...44,760,044
Ensembl chr19:44,747,705...44,760,044
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of BIRC3 mRNA] CTD PMID:24530881 NCBI chr11:102,317,373...102,339,403
Ensembl chr11:102,317,450...102,339,403
JBrowse link
G CASP3 caspase 3 increases activity EXP hydroxyhydroquinone results in increased activity of CASP3 protein CTD PMID:23776099 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP8 caspase 8 increases activity EXP hydroxyhydroquinone results in increased activity of CASP8 protein CTD PMID:23776099 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G CASP9 caspase 9 increases activity EXP hydroxyhydroquinone results in increased activity of CASP9 protein CTD PMID:23776099 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CCL11 C-C motif chemokine ligand 11 affects expression EXP hydroxyhydroquinone affects the expression of CCL11 protein CTD PMID:17572062 NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
JBrowse link
G CCL2 C-C motif chemokine ligand 2 affects expression EXP hydroxyhydroquinone affects the expression of CCL2 protein CTD PMID:17572062 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL3 C-C motif chemokine ligand 3 affects expression EXP hydroxyhydroquinone affects the expression of CCL3 protein CTD PMID:17572062 NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
JBrowse link
G CCL4 C-C motif chemokine ligand 4 affects expression
increases expression
multiple interactions
EXP hydroxyhydroquinone affects the expression of CCL4 protein
hydroxyhydroquinone results in increased expression of CCL4 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CCL4 mRNA]
CTD PMID:17572062 PMID:24530881 NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
JBrowse link
G CCL5 C-C motif chemokine ligand 5 affects expression EXP hydroxyhydroquinone affects the expression of CCL5 protein CTD PMID:17572062 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CHAC1 mRNA] CTD PMID:24530881 NCBI chr15:40,942,137...40,956,518
Ensembl chr15:40,952,962...40,956,512
JBrowse link
G CSF1R colony stimulating factor 1 receptor multiple interactions EXP hydroxyhydroquinone promotes the reaction [[CSF1R protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CSF2 colony stimulating factor 2 multiple interactions ISO hydroxyhydroquinone promotes the reaction [[CSF2 protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CTTN cortactin increases expression EXP hydroxyhydroquinone results in increased expression of CTTN mRNA CTD PMID:17572062 NCBI chr11:70,398,529...70,436,579
Ensembl chr11:70,398,404...70,436,584
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL2 mRNA] CTD PMID:24530881 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL3 mRNA] CTD PMID:24530881 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 affects expression
increases expression
multiple interactions
EXP hydroxyhydroquinone affects the expression of CXCL8 protein
hydroxyhydroquinone results in increased expression of CXCL8 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of CXCL8 mRNA]
CTD PMID:17572062 PMID:24530881 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases expression EXP hydroxyhydroquinone results in increased expression of CYP1B1 mRNA CTD PMID:17572062 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 increases expression EXP hydroxyhydroquinone results in increased expression of CYP27A1 mRNA CTD PMID:17572062 NCBI chr 2:218,781,733...218,815,293
Ensembl chr 2:218,781,749...218,815,293
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions EXP [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone CTD PMID:15051535 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of DDIT4 mRNA] CTD PMID:24530881 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,924...72,276,036
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of DGAT2 mRNA] CTD PMID:24530881 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP hydroxyhydroquinone results in increased expression of DNAJB1 mRNA CTD PMID:17572062 NCBI chr19:14,514,769...14,530,597
Ensembl chr19:14,514,769...14,529,770
Ensembl chr19:14,514,769...14,529,770
JBrowse link
G EGR1 early growth response 1 increases expression
multiple interactions
EXP hydroxyhydroquinone results in increased expression of EGR1 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of EGR1 mRNA]
CTD PMID:24530881 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G EIF3A eukaryotic translation initiation factor 3 subunit A decreases expression EXP hydroxyhydroquinone results in decreased expression of EIF3A mRNA CTD PMID:17572062 NCBI chr10:119,033,670...119,080,817
Ensembl chr10:119,033,670...119,080,823
JBrowse link
G EIF3L eukaryotic translation initiation factor 3 subunit L decreases expression EXP hydroxyhydroquinone results in decreased expression of EIF3L mRNA CTD PMID:17572062 NCBI chr22:37,848,868...37,889,407
Ensembl chr22:37,848,868...37,889,407
JBrowse link
G ENG endoglin multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ENG mRNA] CTD PMID:24530881 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G ERO1A endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP hydroxyhydroquinone results in increased expression of ERO1A mRNA CTD PMID:17572062 NCBI chr14:52,639,915...52,695,750
Ensembl chr14:52,639,915...52,695,900
JBrowse link
G EVA1B eva-1 homolog B increases expression EXP hydroxyhydroquinone results in increased expression of EVA1B mRNA CTD PMID:17572062 NCBI chr 1:36,322,030...36,324,154
Ensembl chr 1:36,322,031...36,324,154
JBrowse link
G FAS Fas cell surface death receptor increases expression EXP hydroxyhydroquinone results in increased expression of FAS protein CTD PMID:23776099 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand increases expression EXP hydroxyhydroquinone results in increased expression of FASLG protein CTD PMID:23776099 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FDXR ferredoxin reductase increases expression EXP hydroxyhydroquinone results in increased expression of FDXR mRNA CTD PMID:17572062 NCBI chr17:74,862,497...74,872,994
Ensembl chr17:74,862,497...74,873,031
JBrowse link
G GABPB2 GA binding protein transcription factor subunit beta 2 increases expression EXP hydroxyhydroquinone results in increased expression of GABPB2 mRNA CTD PMID:17572062 NCBI chr 1:151,070,180...151,125,542
Ensembl chr 1:151,070,578...151,125,542
JBrowse link
G GATA1 GATA binding protein 1 multiple interactions
affects methylation
EXP hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]
hydroxyhydroquinone affects the methylation of GATA1 promoter
CTD PMID:21414390 PMID:30327826 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,562...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G GATA2 GATA binding protein 2 multiple interactions
decreases expression
EXP hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]
hydroxyhydroquinone results in decreased expression of GATA2 mRNA
CTD PMID:21414390 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G GGA1 golgi associated, gamma adaptin ear containing, ARF binding protein 1 increases expression EXP hydroxyhydroquinone results in increased expression of GGA1 mRNA CTD PMID:17572062 NCBI chr22:37,608,474...37,633,564
Ensembl chr22:37,608,725...37,633,564
JBrowse link
G GNAZ G protein subunit alpha z increases expression EXP hydroxyhydroquinone results in increased expression of GNAZ mRNA CTD PMID:17572062 NCBI chr22:23,070,519...23,125,037
Ensembl chr22:23,070,519...23,125,032
JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta increases expression EXP hydroxyhydroquinone results in increased expression of GP1BB mRNA CTD PMID:17572062 NCBI chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771
JBrowse link
G GYPA glycophorin A (MNS blood group) decreases expression EXP hydroxyhydroquinone results in decreased expression of GYPA protein CTD PMID:21414390 NCBI chr 4:144,109,303...144,140,854
Ensembl chr 4:144,109,303...144,140,751
JBrowse link
G H2AC18 H2A clustered histone 18 increases expression EXP hydroxyhydroquinone results in increased expression of H2AC18 mRNA CTD PMID:17572062 NCBI chr 1:149,842,218...149,842,750
Ensembl chr 1:149,842,188...149,842,736
JBrowse link
G H2BC8 H2B clustered histone 8 increases expression EXP hydroxyhydroquinone results in increased expression of H2BC8 mRNA CTD PMID:17572062 NCBI chr 6:26,216,200...26,216,688
Ensembl chr 6:26,215,159...26,216,692
JBrowse link
G HBB hemoglobin subunit beta multiple interactions EXP Decitabine inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]]; hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]; trichostatin A inhibits the reaction [hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HBB mRNA]] CTD PMID:21414390 PMID:30327826 NCBI chr11:5,225,464...5,227,071
Ensembl chr11:5,225,464...5,229,395
JBrowse link
G HES1 hes family bHLH transcription factor 1 increases expression EXP hydroxyhydroquinone results in increased expression of HES1 mRNA CTD PMID:17572062 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 decreases expression EXP hydroxyhydroquinone results in decreased expression of HLA-DPA1 mRNA CTD PMID:17572062 NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 decreases expression EXP hydroxyhydroquinone results in decreased expression of HLA-DPB1 mRNA CTD PMID:17572062 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HMBS hydroxymethylbilane synthase multiple interactions EXP hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of HMBS mRNA] CTD PMID:21414390 NCBI chr11:119,084,864...119,093,549
Ensembl chr11:119,084,866...119,093,549
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:24530881 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression EXP hydroxyhydroquinone results in increased expression of HSP90AA1 mRNA CTD PMID:17572062 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP hydroxyhydroquinone results in increased expression of HSPA1A mRNA CTD PMID:17572062 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression EXP hydroxyhydroquinone results in increased expression of HSPA1B mRNA CTD PMID:17572062 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G IFNG interferon gamma multiple interactions ISO [IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide; IFNG protein promotes the reaction [[Lipopolysaccharides co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide]; Lipopolysaccharides promotes the reaction [[IFNG protein co-treated with hydroxyhydroquinone] results in increased abundance of Nitric Oxide] CTD PMID:7884313 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL10 interleukin 10 multiple interactions EXP hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein] CTD PMID:17572062 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL6 interleukin 6 increases expression EXP hydroxyhydroquinone results in increased expression of IL6 protein CTD PMID:17572062 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGA2B integrin subunit alpha 2b increases expression EXP hydroxyhydroquinone results in increased expression of ITGA2B mRNA CTD PMID:17572062 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649
JBrowse link
G ITGB3 integrin subunit beta 3 increases expression EXP hydroxyhydroquinone results in increased expression of ITGB3 mRNA CTD PMID:17572062 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G JARID2 jumonji and AT-rich interaction domain containing 2 increases expression EXP hydroxyhydroquinone results in increased expression of JARID2 mRNA CTD PMID:17572062 NCBI chr 6:15,245,975...15,522,042
Ensembl chr 6:15,246,069...15,522,042
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of JUN mRNA] CTD PMID:24530881 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KCND1 potassium voltage-gated channel subfamily D member 1 decreases expression EXP hydroxyhydroquinone results in decreased expression of KCND1 mRNA CTD PMID:17572062 NCBI chr  X:48,960,983...48,972,103
Ensembl chr  X:48,961,378...48,971,844
JBrowse link
G KEAP1 kelch like ECH associated protein 1 increases expression EXP hydroxyhydroquinone results in increased expression of KEAP1 mRNA CTD PMID:17572062 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KLF2 Kruppel like factor 2 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLF2 mRNA] CTD PMID:24530881 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,817...16,327,874
Ensembl chr19:16,324,817...16,327,874
JBrowse link
G KLHDC7B kelch domain containing 7B increases expression
multiple interactions
EXP hydroxyhydroquinone results in increased expression of KLHDC7B mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of KLHDC7B mRNA]
CTD PMID:24530881 NCBI chr22:50,545,899...50,551,023
Ensembl chr22:50,545,899...50,551,023
JBrowse link
G LINGO3 leucine rich repeat and Ig domain containing 3 decreases expression
multiple interactions
EXP hydroxyhydroquinone results in decreased expression of LINGO3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of LINGO3 mRNA]
CTD PMID:24530881 NCBI chr19:2,289,784...2,308,154
Ensembl chr19:2,289,784...2,292,024
JBrowse link
G NANOS1 nanos C2HC-type zinc finger 1 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANOS1 mRNA] CTD PMID:24530881 NCBI chr10:119,029,714...119,033,730
Ensembl chr10:119,029,714...119,033,730
JBrowse link
G NANP N-acetylneuraminic acid phosphatase multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of NANP mRNA] CTD PMID:24530881 NCBI chr20:25,612,935...25,624,014
Ensembl chr20:25,612,935...25,624,014
JBrowse link
G NCK2 NCK adaptor protein 2 increases expression EXP hydroxyhydroquinone results in increased expression of NCK2 mRNA CTD PMID:17572062 NCBI chr 2:105,744,649...105,894,274
Ensembl chr 2:105,744,912...105,894,274
JBrowse link
G NEU3 neuraminidase 3 increases expression EXP hydroxyhydroquinone results in increased expression of NEU3 mRNA CTD PMID:23776099 NCBI chr11:74,988,644...75,010,907
Ensembl chr11:74,988,279...75,018,893
JBrowse link
G NFE2 nuclear factor, erythroid 2 multiple interactions EXP hydroxyhydroquinone inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] CTD PMID:21414390 NCBI chr12:54,292,111...54,301,015
Ensembl chr12:54,292,111...54,301,015
JBrowse link
G NFKBIA NFKB inhibitor alpha increases expression
multiple interactions
EXP hydroxyhydroquinone results in increased expression of NFKBIA mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of NFKBIA mRNA]
CTD PMID:24530881 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,511...35,404,749
Ensembl chr14:35,401,511...35,404,749
JBrowse link
G PDE11A phosphodiesterase 11A multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PDE11A mRNA] CTD PMID:24530881 NCBI chr 2:177,623,244...178,108,339
Ensembl chr 2:177,628,069...178,108,339
Ensembl chr 2:177,628,069...178,108,339
JBrowse link
G PHLDA1 pleckstrin homology like domain family A member 1 increases expression EXP hydroxyhydroquinone results in increased expression of PHLDA1 mRNA CTD PMID:17572062 NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,033,932
JBrowse link
G PLIN2 perilipin 2 increases expression EXP hydroxyhydroquinone results in increased expression of PLIN2 mRNA CTD PMID:17572062 NCBI chr 9:19,108,391...19,127,518
Ensembl chr 9:19,108,375...19,149,290
JBrowse link
G POLR1G RNA polymerase I subunit G multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of POLR1G mRNA] CTD PMID:24530881 NCBI chr19:45,406,644...45,410,737
Ensembl chr19:45,406,644...45,410,737
Ensembl chr19:45,406,644...45,410,737
JBrowse link
G PPP1R12A protein phosphatase 1 regulatory subunit 12A increases expression EXP hydroxyhydroquinone results in increased expression of PPP1R12A mRNA CTD PMID:17572062 NCBI chr12:79,773,563...79,935,460
Ensembl chr12:79,773,563...79,935,460
JBrowse link
G PRDM12 PR/SET domain 12 decreases expression
multiple interactions
EXP hydroxyhydroquinone results in decreased expression of PRDM12 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRDM12 mRNA]
CTD PMID:24530881 NCBI chr 9:130,664,594...130,682,983
Ensembl chr 9:130,664,594...130,682,986
Ensembl chr 9:130,664,594...130,682,986
JBrowse link
G PRTN3 proteinase 3 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PRTN3 mRNA] CTD PMID:24530881 NCBI chr19:840,965...848,175
Ensembl chr19:840,999...848,175
JBrowse link
G PRUNE1 prune exopolyphosphatase 1 increases expression EXP hydroxyhydroquinone results in increased expression of PRUNE1 mRNA CTD PMID:17572062 NCBI chr 1:151,008,405...151,035,713
Ensembl chr 1:151,008,420...151,035,713
JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 decreases expression
multiple interactions
EXP hydroxyhydroquinone results in decreased expression of PTPN3 mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of PTPN3 mRNA]
CTD PMID:24530881 NCBI chr 9:109,375,694...109,538,395
Ensembl chr 9:109,375,466...109,498,313
JBrowse link
G RAB22A RAB22A, member RAS oncogene family increases expression EXP hydroxyhydroquinone results in increased expression of RAB22A mRNA CTD PMID:17572062 NCBI chr20:58,309,715...58,367,507
Ensembl chr20:58,309,715...58,367,507
JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of RELB mRNA] CTD PMID:24530881 NCBI chr19:45,001,449...45,038,194
Ensembl chr19:45,001,449...45,038,198
JBrowse link
G RILP Rab interacting lysosomal protein decreases expression
multiple interactions
EXP hydroxyhydroquinone results in decreased expression of RILP mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RILP mRNA]
CTD PMID:24530881 NCBI chr17:1,646,150...1,650,077
Ensembl chr17:1,646,145...1,649,866
JBrowse link
G RPL15 ribosomal protein L15 decreases expression EXP hydroxyhydroquinone results in decreased expression of RPL15 mRNA CTD PMID:17572062 NCBI chr 3:23,916,545...23,924,631
Ensembl chr 3:23,916,545...23,924,374
Ensembl chr 3:23,916,545...23,924,374
JBrowse link
G RPL5 ribosomal protein L5 decreases expression EXP hydroxyhydroquinone results in decreased expression of RPL5 mRNA CTD PMID:17572062 NCBI chr 1:92,831,986...92,841,924
Ensembl chr 1:92,832,013...92,841,924
JBrowse link
G RTN4R reticulon 4 receptor decreases expression
multiple interactions
EXP hydroxyhydroquinone results in decreased expression of RTN4R mRNA
4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of RTN4R mRNA]
CTD PMID:24530881 NCBI chr22:20,241,415...20,268,318
Ensembl chr22:20,241,415...20,283,246
JBrowse link
G SCIMP SLP adaptor and CSK interacting membrane protein multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of SCIMP mRNA] CTD PMID:24530881 NCBI chr17:5,208,920...5,234,860
Ensembl chr17:5,208,920...5,234,860
JBrowse link
G SERPINF1 serpin family F member 1 decreases expression EXP hydroxyhydroquinone results in decreased expression of SERPINF1 mRNA CTD PMID:17572062 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G SESN2 sestrin 2 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of SESN2 mRNA] CTD PMID:24530881 NCBI chr 1:28,259,452...28,282,491
Ensembl chr 1:28,259,518...28,282,491
JBrowse link
G SH3BP2 SH3 domain binding protein 2 increases expression EXP hydroxyhydroquinone results in increased expression of SH3BP2 mRNA CTD PMID:17572062 NCBI chr 4:2,793,085...2,841,096
Ensembl chr 4:2,793,071...2,841,098
JBrowse link
G SORL1 sortilin related receptor 1 decreases expression EXP hydroxyhydroquinone results in decreased expression of SORL1 mRNA CTD PMID:17572062 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
JBrowse link
G SRSF9 serine and arginine rich splicing factor 9 decreases expression EXP hydroxyhydroquinone results in decreased expression of SRSF9 mRNA CTD PMID:17572062 NCBI chr12:120,461,672...120,469,748
Ensembl chr12:120,461,672...120,469,748
JBrowse link
G ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 decreases expression EXP hydroxyhydroquinone results in decreased expression of ST3GAL3 mRNA CTD PMID:23776099 NCBI chr 1:43,707,465...43,931,164
Ensembl chr 1:43,705,824...43,931,165
JBrowse link
G STEAP3 STEAP3 metalloreductase multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of STEAP3 mRNA] CTD PMID:24530881 NCBI chr 2:119,222,476...119,265,652
Ensembl chr 2:119,223,831...119,265,652
JBrowse link
G TFRC transferrin receptor decreases expression
multiple interactions
EXP hydroxyhydroquinone results in decreased expression of TFRC protein
hydroxyhydroquinone promotes the reaction [Hemin results in decreased expression of TFRC mRNA]
CTD PMID:21414390 NCBI chr 3:196,018,694...196,082,123
Ensembl chr 3:196,027,183...196,082,096
JBrowse link
G TLR9 toll like receptor 9 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TLR9 mRNA] CTD PMID:24530881 NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,226,163
JBrowse link
G TMEM158 transmembrane protein 158 increases expression EXP hydroxyhydroquinone results in increased expression of TMEM158 mRNA CTD PMID:17572062 NCBI chr 3:45,224,466...45,226,287
Ensembl chr 3:45,224,466...45,226,287
JBrowse link
G TNF tumor necrosis factor increases expression EXP hydroxyhydroquinone results in increased expression of TNF mRNA CTD PMID:17572062 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 multiple interactions
increases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in increased expression of TNFAIP6 mRNA] CTD PMID:24530881 NCBI chr 2:151,357,592...151,380,046
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TNFRSF8 mRNA] CTD PMID:24530881 NCBI chr 1:12,063,303...12,144,213
Ensembl chr 1:12,063,303...12,144,207
JBrowse link
G TOP2A DNA topoisomerase II alpha decreases activity EXP hydroxyhydroquinone results in decreased activity of TOP2A protein CTD PMID:7586126 NCBI chr17:40,388,525...40,417,902
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TTLL4 tubulin tyrosine ligase like 4 increases expression EXP hydroxyhydroquinone results in increased expression of TTLL4 mRNA CTD PMID:17572062 NCBI chr 2:218,710,835...218,757,484
Ensembl chr 2:218,710,835...218,755,416
JBrowse link
G TTTY13 testis-specific transcript, Y-linked 13 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of TTTY13 mRNA] CTD PMID:24530881 NCBI chr  Y:21,583,600...21,594,666
Ensembl chr  Y:21,565,092...21,605,081
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP hydroxyhydroquinone results in increased expression of TXNRD1 mRNA CTD PMID:17572062 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G ZBTB42 zinc finger and BTB domain containing 42 multiple interactions
decreases expression
EXP 4-aminobenzhydrazide inhibits the reaction [hydroxyhydroquinone results in decreased expression of ZBTB42 mRNA] CTD PMID:24530881 NCBI chr14:104,800,554...104,804,712
Ensembl chr14:104,800,596...104,804,712
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24381
    chemical entity 24349
      molecular entity 24309
        polyatomic entity 24233
          heteroatomic molecular entity 23831
            hydroxides 22348
              organic hydroxy compound 20740
                phenols 19445
                  benzenetriol 2704
                    benzene-1,2,4-triol 110
Path 2
Term Annotations click to browse term
  CHEBI ontology 24381
    subatomic particle 24338
      composite particle 24338
        hadron 24338
          baryon 24338
            nucleon 24338
              atomic nucleus 24338
                atom 24338
                  main group element atom 24185
                    p-block element atom 24185
                      chalcogen 23222
                        oxygen atom 23097
                          oxygen molecular entity 23097
                            hydroxides 22348
                              organic hydroxy compound 20740
                                polyol 8059
                                  triol 6226
                                    benzenetriol 2704
                                      benzene-1,2,4-triol 110
paths to the root