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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:D-mannitol
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Accession:CHEBI:16899 term browser browse the term
Definition:The D-enantiomer of mannitol.
Synonyms:related_synonym: (2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol;   (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol;   E-421;   E421;   Formula=C6H14O6;   InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1;   InChIKey=FBPFZTCFMRRESA-KVTDHHQDSA-N;   Mannitol;   Osmitrol;   SMILES=OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO;   dulcite;   manna sugar;   mannite
 alt_id: CHEBI:12996;   CHEBI:130180;   CHEBI:21050;   CHEBI:44192;   CHEBI:6686
 xref: Beilstein:1721898;   CAS:69-65-8;   DrugBank:DB00742;   Drug_Central:935;   Gmelin:83161;   HMDB:HMDB0000765;   KEGG:C00392;   KEGG:D00062;   KNApSAcK:C00001165
 xref_mesh: MESH:D008353
 xref: MetaCyc:MANNITOL;   PDBeChem:MTL;   PMID:11784135;   PMID:12646037;   PMID:15658873;   PMID:15863337;   PMID:16854081;   PMID:16901854;   PMID:17336832;   PMID:17420133;   PMID:17827020;   PMID:17973471;   PMID:17979222;   PMID:17983214;   PMID:18207412;   PMID:18220330;   PMID:22770225;   PMID:24643482;   PMID:25108762;   Reaxys:1721898;   Wikipedia:Mannitol


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D-mannitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1 mRNA]; Mannitol inhibits the reaction [Vitamin A results in decreased expression of ABCB1A mRNA] CTD PMID:15327746 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO Mannitol results in decreased expression of ACACB mRNA CTD PMID:25270620 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acly ATP citrate lyase increases expression ISO Mannitol results in increased expression of ACLY mRNA CTD PMID:25270620 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 increases expression ISO Mannitol results in increased expression of ADAMTS18 mRNA CTD PMID:25270620 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781
JBrowse link
G Aida axin interactor, dorsalization associated decreases expression ISO Mannitol results in decreased expression of AIDA mRNA CTD PMID:25270620 NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920
JBrowse link
G Aire autoimmune regulator decreases expression ISO Mannitol results in decreased expression of AIRE mRNA CTD PMID:25270620 NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060
JBrowse link
G Aqp9 aquaporin 9 increases uptake EXP AQP9 protein results in increased uptake of Mannitol CTD PMID:9733774 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression ISO Mannitol results in increased expression of ARHGAP1 mRNA CTD PMID:25270620 NCBI chr 3:77,621,377...77,643,400
Ensembl chr 3:77,620,655...77,643,396
JBrowse link
G Arr3 arrestin 3 increases expression ISO Mannitol results in increased expression of ARR3 mRNA CTD PMID:25270620 NCBI chr  X:65,699,881...65,712,224
Ensembl chr  X:65,698,699...65,712,153
JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation
multiple interactions
EXP Mannitol results in increased phosphorylation of BAD protein
wortmannin inhibits the reaction [Mannitol results in increased phosphorylation of BAD protein]
CTD PMID:15786717 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of BAX protein] CTD PMID:29803612 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO Mannitol results in decreased expression of BBOX1 mRNA CTD PMID:25270620 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Mannitol results in increased expression of BCL2 protein CTD PMID:15786717 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Mannitol results in decreased expression of CABLES2 mRNA CTD PMID:25270620 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:167,347,461...167,362,279
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased activity of CASP3 protein] CTD PMID:10567913 PMID:12011046 PMID:29803612 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO Mannitol results in increased activity of CASP9 protein CTD PMID:12011046 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cbx1 chromobox 1 increases expression ISO Mannitol results in increased expression of CBX1 mRNA CTD PMID:25270620 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
JBrowse link
G Ccdc127 coiled-coil domain containing 127 decreases expression ISO Mannitol results in decreased expression of CCDC127 mRNA CTD PMID:25270620 NCBI chr 1:28,928,420...28,935,885
Ensembl chr 1:28,928,325...28,935,893
JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression ISO Mannitol results in decreased expression of CCN3 mRNA CTD PMID:25270620 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO Mannitol results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264
JBrowse link
G Clcn3 chloride voltage-gated channel 3 affects response to substance ISO CLCN3 protein affects the susceptibility to Mannitol deficiency CTD PMID:22108225 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Ctnna2 catenin alpha 2 decreases expression ISO Mannitol results in decreased expression of CTNNA2 mRNA CTD PMID:25270620 NCBI chr 4:109,293,978...110,443,413
Ensembl chr 4:109,293,978...110,443,522
JBrowse link
G Dbh dopamine beta-hydroxylase increases expression ISO Mannitol results in increased expression of DBH mRNA CTD PMID:25270620 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dctn2 dynactin subunit 2 increases expression ISO Mannitol results in increased expression of DCTN2 mRNA CTD PMID:25270620 NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543
JBrowse link
G Defb3 beta-defensin 3 decreases expression ISO Mannitol results in decreased expression of DEFB7 mRNA CTD PMID:25270620
G Dgka diacylglycerol kinase, alpha increases expression ISO Mannitol results in increased expression of DGKA mRNA CTD PMID:25270620 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
JBrowse link
G Elf2 E74 like ETS transcription factor 2 increases expression ISO Mannitol results in increased expression of ELF2 mRNA CTD PMID:25270620 NCBI chr 2:135,292,291...135,385,942
Ensembl chr 2:135,294,906...135,385,947
JBrowse link
G Fam185a family with sequence similarity 185, member A increases expression ISO Mannitol results in increased expression of FAM185A mRNA CTD PMID:25270620 NCBI chr 4:13,542,022...13,662,967 JBrowse link
G Fam222a family with sequence similarity 222, member A decreases expression ISO Mannitol results in decreased expression of FAM222A mRNA CTD PMID:25270620 NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Mannitol results in increased expression of FOS mRNA CTD PMID:11557636 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gal3st2 galactose-3-O-sulfotransferase 2 decreases expression ISO Mannitol results in decreased expression of GAL3ST2 mRNA CTD PMID:25270620 NCBI chr 9:94,382,456...94,387,990 JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 decreases expression ISO Mannitol results in decreased expression of GAS2L2 mRNA CTD PMID:25270620 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881
JBrowse link
G Gpc6 glypican 6 increases expression ISO Mannitol results in increased expression of GPC6 mRNA CTD PMID:25270620 NCBI chr15:94,030,218...95,027,883
Ensembl chr15:94,029,884...95,024,006
JBrowse link
G Gpr19 G protein-coupled receptor 19 decreases expression ISO Mannitol results in decreased expression of GPR19 mRNA CTD PMID:25270620 NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Mannitol results in increased expression of HMOX1 mRNA CTD PMID:11592956 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Mannitol results in increased expression of HPRT mRNA CTD PMID:25270620 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hrh2 histamine receptor H 2 increases expression ISO Mannitol results in increased expression of HRH2 mRNA CTD PMID:25270620 NCBI chr17:10,368,355...10,407,791
Ensembl chr17:10,368,298...10,407,631
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of ICAM1 protein] CTD PMID:16285992 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein] CTD PMID:10567913 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Rotenone inhibits the reaction [Mannitol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] CTD PMID:23867654 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Mannitol results in increased expression of JUN mRNA CTD PMID:11557636 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Khdc3 KH domain containing 3, subcortical maternal complex member increases expression ISO Mannitol results in increased expression of KHDC3 mRNA CTD PMID:25270620 NCBI chr 8:73,842,344...73,844,248
Ensembl chr 8:73,842,344...73,844,248
JBrowse link
G Krtap11-1 keratin associated protein 11-1 increases expression ISO Mannitol results in increased expression of KRTAP11-1 mRNA CTD PMID:25270620 NCBI chr11:28,808,644...28,814,273
Ensembl chr11:28,810,341...28,810,892
JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Mannitol results in decreased expression of LSM6 mRNA CTD PMID:25270620 NCBI chr19:29,098,254...29,112,858
Ensembl chr19:29,098,214...29,118,682
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K1 protein] CTD PMID:16510265 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of MAP2K2 protein] CTD PMID:16510265 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK1 protein] CTD PMID:10910949 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mta2 metastasis associated 1 family, member 2 increases expression ISO Mannitol results in increased expression of MTA2 mRNA CTD PMID:25270620 NCBI chr 1:205,838,181...205,846,903
Ensembl chr 1:205,837,964...205,846,946
JBrowse link
G Myl9 myosin light chain 9 decreases phosphorylation EXP Mannitol results in decreased phosphorylation of MYL9 protein CTD PMID:17272349 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Mylk3 myosin light chain kinase 3 increases expression ISO Mannitol results in increased expression of MYLK3 mRNA CTD PMID:25270620 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954
JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 increases expression ISO Mannitol results in increased expression of NAALAD2 mRNA CTD PMID:25270620 NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 decreases expression ISO Mannitol results in decreased expression of NDUFA13 mRNA CTD PMID:25270620 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO Mannitol results in increased expression of NFAT5 mRNA CTD PMID:23867654 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nkg7 natural killer cell granule protein 7 increases expression ISO Mannitol results in increased expression of NKG7 mRNA CTD PMID:25270620 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Nppa natriuretic peptide A increases expression ISO Mannitol results in increased expression of NPPA protein CTD PMID:2177369 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nts neurotensin increases transport EXP NTS protein results in increased transport of Mannitol CTD PMID:11208724 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Oat ornithine aminotransferase multiple interactions EXP Mannitol inhibits the reaction [Cyclic AMP results in increased activity of OAT protein] CTD PMID:2827574 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Pcp2 Purkinje cell protein 2 increases expression ISO Mannitol results in increased expression of PCP2 mRNA CTD PMID:25270620 NCBI chr12:1,681,659...1,683,899
Ensembl chr12:1,681,659...1,683,899
JBrowse link
G Pdcd4 programmed cell death 4 increases expression
decreases expression
ISO Mannitol results in increased expression of PDCD4 mRNA
Mannitol results in decreased expression of PDCD4 mRNA
CTD PMID:21873647 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Plcl2 phospholipase C-like 2 decreases expression ISO Mannitol results in decreased expression of PLCL2 mRNA CTD PMID:25270620 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009
JBrowse link
G Plekho1 pleckstrin homology domain containing O1 increases expression ISO Mannitol results in increased expression of PLEKHO1 mRNA CTD PMID:25270620 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785
JBrowse link
G Pou1f1 POU class 1 homeobox 1 increases expression ISO Mannitol results in increased expression of POU1F1 mRNA CTD PMID:25270620 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 decreases expression ISO Mannitol results in decreased expression of PPP1R10 mRNA CTD PMID:25270620 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit increases expression ISO Mannitol results in increased expression of PPP4C mRNA CTD PMID:25270620 NCBI chr 1:181,392,899...181,399,703
Ensembl chr 1:181,392,923...181,399,659
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein alternative form]; Mannitol inhibits the reaction [Glucose results in increased expression of PRKCB protein] CTD PMID:16285992 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of PRKCD protein] CTD PMID:16285992 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Ptger1 prostaglandin E receptor 1 increases expression EXP Mannitol results in increased expression of PTGER1 mRNA CTD PMID:12888618 NCBI chr19:24,470,258...24,473,687
Ensembl chr19:24,467,532...24,473,559
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression EXP Mannitol results in decreased expression of PTGER4 mRNA CTD PMID:12888618 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein]; Mannitol results in decreased phosphorylation of and results in increased degradation of PTK2 protein CTD PMID:12011046 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 decreases expression ISO Mannitol results in decreased expression of RBL1 mRNA CTD PMID:25270620 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbp2 retinol binding protein 2 decreases expression ISO Mannitol results in decreased expression of RBP2 mRNA CTD PMID:25270620 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473
JBrowse link
G Rgl3 ral guanine nucleotide dissociation stimulator-like 3 increases expression ISO Mannitol results in increased expression of RGL3 mRNA CTD PMID:25270620 NCBI chr 8:20,500,846...20,520,471
Ensembl chr 8:20,500,846...20,520,471
JBrowse link
G Samd10 sterile alpha motif domain containing 10 decreases expression ISO Mannitol results in decreased expression of SAMD10 mRNA CTD PMID:25270620 NCBI chr 3:168,700,280...168,704,427
Ensembl chr 3:168,700,284...168,705,248
JBrowse link
G Sbsn suprabasin decreases expression ISO Mannitol results in decreased expression of SBSN mRNA CTD PMID:25270620 NCBI chr 1:85,979,477...86,006,034
Ensembl chr 1:86,001,567...86,006,034
JBrowse link
G Sele selectin E multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of SELE mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of SELE protein] CTD PMID:16285992 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sgsm3 small G protein signaling modulator 3 decreases expression ISO Mannitol results in decreased expression of SGSM3 mRNA CTD PMID:25270620 NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:112,514,630...112,544,108
JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases activity
multiple interactions
EXP Mannitol results in increased activity of SLC12A1 protein
[Mannitol results in increased activity of SLC12A1 protein] which results in increased import of Water
CTD PMID:12433675 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc2a8 solute carrier family 2 member 8 decreases expression ISO Mannitol results in decreased expression of SLC2A8 mRNA CTD PMID:25270620 NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP Mannitol inhibits the reaction [Vitamin A results in increased phosphorylation of SRC protein] CTD PMID:16510265 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stx8 syntaxin 8 decreases expression ISO Mannitol results in decreased expression of STX8 mRNA CTD PMID:25270620 NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993
JBrowse link
G Timd4 T-cell immunoglobulin and mucin domain containing 4 decreases expression ISO Mannitol results in decreased expression of TIMD4 mRNA CTD PMID:25270620 NCBI chr10:31,185,751...31,221,843 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Quartz results in increased secretion of TNF protein] CTD PMID:19298665 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Mannitol results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] CTD PMID:29803612 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression
ISO Mannitol results in decreased expression of TPD52 mRNA
Mannitol results in increased expression of TPD52 mRNA
CTD PMID:21873647 NCBI chr 2:92,735,246...92,816,079
Ensembl chr 2:92,735,620...92,816,622
JBrowse link
G Triml1 tripartite motif family-like 1 increases expression ISO Mannitol results in increased expression of TRIML1 mRNA CTD PMID:25270620 NCBI chr16:48,994,968...49,005,343
Ensembl chr16:48,997,252...49,005,417
JBrowse link
G Ulbp1 UL16 binding protein 1 increases expression ISO Mannitol results in increased expression of ULBP1 mRNA CTD PMID:25270620 NCBI chr 1:1,694,255...1,716,160 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 mRNA]; Mannitol inhibits the reaction [Glucose results in increased expression of VCAM1 protein] CTD PMID:16285992 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Wdr20 WD repeat domain 20 decreases expression ISO Mannitol results in decreased expression of WDR20 mRNA CTD PMID:25270620 NCBI chr 6:129,751,952...129,821,464
Ensembl chr 6:129,752,014...129,847,339
JBrowse link
G Zfp13 zinc finger protein 13 decreases expression ISO Mannitol results in decreased expression of ZFP13 mRNA CTD PMID:25270620 NCBI chr10:12,615,470...12,623,615
Ensembl chr10:12,615,190...12,623,615
JBrowse link
G Zg16 zymogen granule protein 16 decreases expression ISO Mannitol results in decreased expression of ZG16 mRNA CTD PMID:25270620 NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        hapten 3021
          D-mannitol 92
            1,5-anhydro-D-mannitol 0
            2-O-(alpha-D-Manp)-D-Man-OH 0
            D-Glcp-(1->1)-D-Man-OH 0
            D-mannitol 1,6-bis(methanesulfonate) 0
            D-mannitol 1-phosphate 0
            alpha-D-Galp-(1->2)-D-mannitol 0
            alpha-D-Manp-(1->1)-D-Man-OH 0
            alpha-D-Manp-(1->3)-Man-OH 0
            alpha-L-Fucp-(1->2)-D-Man-OH 0
            alpha-L-Fucp-(1->3)-D-mannitol 0
            beta-D-Galf-(1->3)-D-Man-OH 0
            beta-D-Galp-(1->3)-Man-OH 0
            isomalt 0
            mannopine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon group molecular entity 19640
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organochalcogen compound 19064
                                organooxygen compound 19014
                                  carbohydrates and carbohydrate derivatives 12341
                                    carbohydrate 12341
                                      alditol 1889
                                        hexitol 113
                                          mannitol 92
                                            D-mannitol 92
                                              1,5-anhydro-D-mannitol 0
                                              2-O-(alpha-D-Manp)-D-Man-OH 0
                                              D-Glcp-(1->1)-D-Man-OH 0
                                              D-mannitol 1,6-bis(methanesulfonate) 0
                                              D-mannitol 1-phosphate 0
                                              alpha-D-Galp-(1->2)-D-mannitol 0
                                              alpha-D-Manp-(1->1)-D-Man-OH 0
                                              alpha-D-Manp-(1->3)-Man-OH 0
                                              alpha-L-Fucp-(1->2)-D-Man-OH 0
                                              alpha-L-Fucp-(1->3)-D-mannitol 0
                                              beta-D-Galf-(1->3)-D-Man-OH 0
                                              beta-D-Galp-(1->3)-Man-OH 0
                                              isomalt 0
                                              mannopine 0
paths to the root