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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sphinganine 1-phosphate
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Accession:CHEBI:16893 term browser browse the term
Definition:A sphingoid 1-phosphate that is the monophosphorylated derivative of sphinganine.
Synonyms:exact_synonym: sphinganine 1-(dihydrogen phosphate)
 related_synonym: (2S,3R)-2-amino-3-hydroxyoctadecyl dihydrogen phosphate;   Formula=C18H40NO5P;   InChI=1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1;   InChIKey=YHEDRJPUIRMZMP-ZWKOTPCHSA-N;   SMILES=CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O;   dihydrosphingosine-1-phosphate
 alt_id: CHEBI:15100;   CHEBI:23767;   CHEBI:9222
 xref: Beilstein:6780476;   CAS:19794-97-9;   KEGG:C01120;   KNApSAcK:C00007541;   LIPID_MAPS_instance:LMSP01050002
 xref_mesh: MESH:C060504
 xref: Reaxys:6780476
 cyclic_relationship: is_conjugate_acid_of CHEBI:57939


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sphinganine 1-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO dihydrosphingosine 1-phosphate inhibits the reaction [dihydrosphingosine 1-phosphate results in increased expression of PTGS2 mRNA]; dihydrosphingosine 1-phosphate inhibits the reaction [dihydrosphingosine 1-phosphate results in increased expression of PTGS2 protein]; dihydrosphingosine 1-phosphate inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]; dihydrosphingosine 1-phosphate inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein]; sphingosine 1-phosphate inhibits the reaction [dihydrosphingosine 1-phosphate results in increased expression of PTGS2 mRNA]; sphingosine 1-phosphate inhibits the reaction [dihydrosphingosine 1-phosphate results in increased expression of PTGS2 protein]
dihydrosphingosine 1-phosphate results in increased expression of PTGS2 mRNA; dihydrosphingosine 1-phosphate results in increased expression of PTGS2 protein
CTD PMID:18612546 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Spns2 sphingolipid transporter 2 decreases abundance ISO SPNS2 protein results in decreased abundance of dihydrosphingosine 1-phosphate CTD PMID:29772789 NCBI chr10:57,067,348...57,105,969
Ensembl chr10:57,066,897...57,105,957
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        biochemical role 19389
          metabolite 19364
            eukaryotic metabolite 19052
              animal metabolite 18892
                mammalian metabolite 18891
                  mouse metabolite 18588
                    sphinganine 1-phosphate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      chalcogen 19469
                        oxygen atom 19445
                          oxygen molecular entity 19445
                            hydroxides 19180
                              oxoacid 18498
                                pnictogen oxoacid 10685
                                  phosphorus oxoacid 9666
                                    phosphoric acids 8466
                                      phosphoric acid 8466
                                        phosphoric acid derivative 8172
                                          phosphate 8172
                                            organic phosphate 8171
                                              phospholipid 302
                                                phosphosphingolipid 86
                                                  sphingoid 1-phosphate 44
                                                    sphinganine 1-phosphate 2
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