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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alizarin
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Accession:CHEBI:16866 term browser browse the term
Definition:A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2.
Synonyms:exact_synonym: 1,2-dihydroxyanthracene-9,10-dione
 related_synonym: 1,2-Anthraquinonediol;   1,2-Dihydroxyanthraquinone;   1,2-dihydroxy-9,10-anthraquinone;   1,2-dihydroxyanthra-9,10-quinone;   Alizarin B;   Alizarin Red;   Az;   C.I. 58000;   Dihydroxy-9,10-anthracenedione;   Dihydroxyanthraquinone;   Formula=C14H8O4;   InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H;   InChIKey=RGCKGOZRHPZPFP-UHFFFAOYSA-N;   Mordant Red 11;   SMILES=Oc1ccc2C(=O)c3ccccc3C(=O)c2c1O;   Turkey Red;   pigment red 83
 alt_id: CHEBI:13756;   CHEBI:22312;   CHEBI:2574;   CHEBI:87354
 xref: Beilstein:1914037;   CAS:72-48-0;   Gmelin:34541;   KEGG:C01474;   KNApSAcK:C00002785;   LINCS:LSM-25636
 xref_mesh: MESH:C010078
 xref: MetaCyc:ALIZARIN;   PMID:14500876;   PMID:1650428;   PMID:16851024;   PMID:23225693;   PMID:25025314;   PMID:25497981;   PMID:25651191;   PMID:26178874;   PMID:26763935;   Reaxys:1914037;   Wikipedia:Alizarin



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alizarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO alizarin results in decreased activity of CYP1A1 protein CTD PMID:12379470 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO alizarin results in decreased activity of CYP1A2 protein CTD PMID:12379470 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO alizarin results in decreased activity of CYP1B1 protein CTD PMID:12379470 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO alizarin results in decreased activity of CYP2E1 protein CTD PMID:12379470 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO alizarin binds to and results in increased activity of ESR1 protein CTD PMID:20707409 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of alizarin CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of alizarin CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of alizarin CTD PMID:7574722 NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        dye 1366
          alizarin 8
            1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      ketone 17115
                                        cyclic ketone 15670
                                          quinone 8521
                                            acenoquinone 7582
                                              anthraquinone 503
                                                hydroxyanthraquinones 492
                                                  dihydroxyanthraquinone 340
                                                    alizarin 8
                                                      1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone 0
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