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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:gamma-aminobutyric acid
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Accession:CHEBI:16865 term browser browse the term
Definition:A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Synonyms:related_synonym: 4-aminobutanoic acid;   4-aminobutyric acid;   4Abu;   Formula=C4H9NO2;   GABA;   GAMMA-AMINO-BUTANOIC ACID;   InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7);   InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-N;   SMILES=NCCCC(O)=O;   gamma-Aminobuttersaeure;   gamma-amino-n-butyric acid;   gamma-aminobutanoic acid;   omega-aminobutyric acid;   piperidic acid;   piperidinic acid
 alt_id: CHEBI:1786;   CHEBI:193777;   CHEBI:20318;   CHEBI:40483
 xref: BPDB:2298;   Beilstein:906818;   CAS:56-12-2;   DrugBank:DB02530;   Drug_Central:1262;   Gmelin:49775;   HMDB:HMDB0000112;   KEGG:C00334;   KEGG:D00058;   KNApSAcK:C00001337;   LIPID_MAPS_instance:LMFA01100039
 xref_mesh: MESH:D005680
 xref: MetaCyc:4-AMINO-BUTYRATE;   PDBeChem:ABU;   PMID:10630630;   PMID:10930630;   PMID:16276116;   PMID:21614609;   PMID:22770225;   Reaxys:906818;   Wikipedia:Gamma-Aminobutyric_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30566;   is_tautomer_of CHEBI:59888


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gamma-aminobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase multiple interactions
decreases expression
ISO
EXP
[Vigabatrin results in decreased activity of ABAT protein] which results in increased abundance of gamma-Aminobutyric Acid
gamma-Aminobutyric Acid results in decreased expression of ABAT mRNA
CTD PMID:11468302 PMID:12748807 PMID:26924987 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Adcy7 adenylate cyclase 7 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of ADCY7 mRNA CTD PMID:26924987 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Adora1 adenosine A1 receptor decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of ADORA1 mRNA CTD PMID:26924987 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP gamma-Aminobutyric Acid results in increased expression of ADORA2A mRNA CTD PMID:26924987 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP gamma-Aminobutyric Acid results in increased phosphorylation of AKT1 protein CTD PMID:29708300 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of ALDH5A1 mRNA CTD PMID:26924987 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases abundance ISO ALPL gene mutant form results in decreased abundance of gamma-Aminobutyric Acid CTD PMID:7550313 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Aoc1 amine oxidase, copper containing 1 increases abundance EXP AOC1 protein results in increased abundance of gamma-Aminobutyric Acid CTD PMID:1644166 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation EXP gamma-Aminobutyric Acid results in increased phosphorylation of BAD protein CTD PMID:29708300 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP gamma-Aminobutyric Acid results in increased expression of BCL2 protein CTD PMID:29708300 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
EXP gamma-Aminobutyric Acid results in increased expression of BCL2L1 protein
gamma-Aminobutyric Acid results in decreased expression of BCL2L1 mRNA
CTD PMID:26924987 PMID:29708300 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP gamma-Aminobutyric Acid inhibits the reaction [decamethrin results in increased expression of BDNF exon] CTD PMID:22079160 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein affects expression EXP gamma-Aminobutyric Acid affects the expression of BGLAP protein CTD PMID:24098073 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of BIRC3 mRNA CTD PMID:26924987 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP gamma-Aminobutyric Acid results in increased expression of BIRC5 mRNA CTD PMID:26924987 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp2 bone morphogenetic protein 2 affects expression EXP gamma-Aminobutyric Acid affects the expression of BMP2 mRNA CTD PMID:24098073 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of CACNA1A mRNA CTD PMID:26924987 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of CACNA1B mRNA CTD PMID:26924987 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Calcr calcitonin receptor affects expression EXP gamma-Aminobutyric Acid affects the expression of CALCR mRNA CTD PMID:24098073 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Casp3 caspase 3 decreases cleavage
multiple interactions
EXP
ISO
gamma-Aminobutyric Acid results in decreased cleavage of CASP3 protein
gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]
CTD PMID:29044621 PMID:29708300 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 decreases cleavage EXP gamma-Aminobutyric Acid results in decreased cleavage of CASP9 protein CTD PMID:29708300 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions EXP
ISO
gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in decreased activity of CAT protein] CTD PMID:28456544 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of CCND1 mRNA CTD PMID:26924987 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO gamma-Aminobutyric Acid results in decreased expression of CDH1 mRNA; gamma-Aminobutyric Acid results in decreased expression of CDH1 protein CTD PMID:32048404 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit multiple interactions ISO gamma-Aminobutyric Acid binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] CTD PMID:8388298 NCBI chr 8:59,561,817...59,590,172
Ensembl chr 8:59,561,721...59,590,172
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit multiple interactions ISO gamma-Aminobutyric Acid binds to and results in increased activity of [CHRNA5 protein co-treated with CHRNB1 protein] CTD PMID:8388298 NCBI chr10:56,390,671...56,403,255
Ensembl chr10:56,390,671...56,403,188
JBrowse link
G Col1a2 collagen type I alpha 2 chain affects expression EXP gamma-Aminobutyric Acid affects the expression of COL1A2 mRNA CTD PMID:24098073 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased expression of CRH mRNA]; gamma-Aminobutyric Acid inhibits the reaction [acephate results in increased secretion of CRH protein]; gamma-Aminobutyric Acid inhibits the reaction [methamidophos results in increased expression of CRH mRNA]; gamma-Aminobutyric Acid inhibits the reaction [methamidophos results in increased secretion of CRH protein] CTD PMID:12039681 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 affects expression EXP gamma-Aminobutyric Acid affects the expression of CX3CL1 mRNA CTD PMID:26924987 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP DRD1 protein promotes the reaction [zonisamide affects the secretion of gamma-Aminobutyric Acid] CTD PMID:19482038 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd3 dopamine receptor D3 affects expression EXP gamma-Aminobutyric Acid affects the expression of DRD3 mRNA CTD PMID:26924987 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd5 dopamine receptor D5 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of DRD5 mRNA CTD PMID:26924987 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Egr1 early growth response 1 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of EGR1 mRNA CTD PMID:26924987 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased phosphorylation of ERN1 protein] CTD PMID:29044621 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO ESR1 protein promotes the reaction [Estradiol inhibits the reaction [Potassium results in increased secretion of gamma-Aminobutyric Acid]] CTD PMID:19211896 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP gamma-Aminobutyric Acid results in increased expression of FGF1 protein CTD PMID:15264218 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf13 fibroblast growth factor 13 increases uptake EXP FGF13 protein results in increased uptake of gamma-Aminobutyric Acid CTD PMID:9751161 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO gamma-Aminobutyric Acid results in decreased expression of FOXA2 mRNA CTD PMID:32048404 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions
decreases expression
increases activity
ISO
EXP
2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Chloral Hydrate inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Chlorobutanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Egtazic Acid inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Enflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Ether inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Fendiline inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein]; Isoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Methoxyflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; sevoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; tert-Butyl Alcohol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]; Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Trifluoroethanol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein]
gamma-Aminobutyric Acid results in decreased expression of GABBR1 mRNA
CTD PMID:10683198 PMID:11125035 PMID:15627515 PMID:26924987 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Egtazic Acid inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Fendiline inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]; Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:11125035 PMID:15627515 PMID:21729720 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
increases expression
increases response to substance
ISO
EXP
1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; 1-(2-methoxyphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 1-(3-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(4-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(4-methoxyphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]; 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Bicuculline promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; fipronil promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]]; gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]; gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]]; gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB3 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; phenylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; phenylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
gamma-Aminobutyric Acid results in increased expression of GABRA1 mRNA
GABRA1 protein results in increased susceptibility to gamma-Aminobutyric Acid
[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Anthracenes analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Bicuculline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Bicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]]; Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; cyclopentaphenanthrene analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; Flumazenil promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]; gamma-Aminobutyric Acid results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]; methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Niflumic Acid promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Steroids analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; Topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]; Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]
CTD PMID:1712603 PMID:1977069 PMID:2165521 PMID:9316872 PMID:10049148 PMID:10825391 PMID:11123204 PMID:11137757 PMID:11156579 PMID:11399263 PMID:11812690 PMID:12939268 PMID:14637376 PMID:15363660 PMID:15588619 PMID:15765150 PMID:17054655 PMID:18275132 PMID:20819908 PMID:20861069 PMID:21111751 PMID:21729720 PMID:22547355 PMID:26344803 PMID:26924987 PMID:27720918 PMID:29038840 PMID:32209479 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO
EXP
Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein]; Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein]]; sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]
[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]
CTD PMID:10683198 PMID:11123204 PMID:15363660 PMID:29038840 NCBI chr14:39,662,411...39,801,082
Ensembl chr14:39,661,968...39,798,302
JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr  X:152,414,332...152,642,607
Ensembl chr  X:152,414,615...152,642,531
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO
EXP
benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]]
benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]
[gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]
CTD PMID:11123204 PMID:18762200 PMID:29038840 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 multiple interactions ISO GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]] CTD PMID:10987858 NCBI chr 1:112,833,941...112,947,482
Ensembl chr 1:112,833,944...112,947,451
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions
increases expression
EXP
ISO
[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; Bicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]; Niflumic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]; topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]
gamma-Aminobutyric Acid results in increased expression of GABRA6 mRNA
delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]
CTD PMID:8632757 PMID:9316872 PMID:11123204 PMID:26924987 PMID:27720918 PMID:29038840 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions
increases expression
ISO
EXP
1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]; Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]; Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]
gamma-Aminobutyric Acid results in increased expression of GABRB1 mRNA
Bicuculline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Flumazenil promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]; methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]
Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]; Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]
CTD PMID:1712603 PMID:1977069 PMID:2165521 PMID:10049148 PMID:10683198 PMID:10825391 PMID:11156579 PMID:21111751 PMID:26924987 PMID:29038840 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions
affects response to substance
ISO
EXP
1-(2-methoxyphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(4-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(4-methoxyphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]; 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Bicuculline promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; fipronil promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]]; GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]; gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]]; Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; phenylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; phenylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
GABRB2 protein affects the susceptibility to gamma-Aminobutyric Acid
[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Anthracenes analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Bicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]]; Bicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]]; Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; cyclopentaphenanthrene analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]; methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]; Niflumic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]; Niflumic Acid promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Steroids analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]]; Topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]
CTD PMID:8161449 PMID:10987858 PMID:11123204 PMID:11137757 PMID:11399263 PMID:11812690 PMID:12939268 PMID:14637376 PMID:15363660 PMID:15588619 PMID:17054655 PMID:18275132 PMID:18762200 PMID:20819908 PMID:20861069 PMID:22547355 PMID:26344803 PMID:27720918 PMID:29038840 PMID:32209479 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 multiple interactions
increases expression
ISO
EXP
[delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]]; delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB3 protein]]; gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG1 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]]; loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]
gamma-Aminobutyric Acid results in increased expression of GABRB3 mRNA
CTD PMID:8161449 PMID:8632757 PMID:9316872 PMID:18762200 PMID:21111751 PMID:26924987 PMID:29038840 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta multiple interactions
decreases expression
ISO
EXP
benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRD protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]]
gamma-Aminobutyric Acid results in decreased expression of GABRD mRNA
benzamide analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRD protein]
CTD PMID:18762200 PMID:26924987 PMID:29038840 NCBI chr 5:172,797,478...172,809,374
Ensembl chr 5:172,797,450...172,809,353
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon multiple interactions
decreases expression
ISO
EXP
Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]
gamma-Aminobutyric Acid results in decreased expression of GABRE mRNA
CTD PMID:10049148 PMID:26924987 NCBI chr  X:152,220,180...152,237,347
Ensembl chr  X:152,218,707...152,237,361
JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 multiple interactions EXP
ISO
Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG1 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]
gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG1 protein]
CTD PMID:15363660 PMID:29038840 NCBI chr14:39,964,502...40,051,306
Ensembl chr14:39,964,588...40,049,354
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions
increases activity
ISO
EXP
1-(2-methoxyphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 1-(3-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(4-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(4-methoxyphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]; 2,4,2',4'-tetrachlorobiphenyl promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 3,5-dibromo-2-(2,4-dibromophenoxy)phenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; [2,2',3,5',6-pentachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,4,2',4'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,4,4'-trichlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [2,5,2',5'-tetrachlorobiphenyl co-treated with gamma-Aminobutyric Acid] binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; [3,5-dibromo-2-(2,4-dibromophenoxy)phenol co-treated with 2,4,2',4'-tetrachlorobiphenyl] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Amphetamine promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Bicuculline promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRG2 protein]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; fipronil promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; Flame Retardants promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; gabazine affects the reaction [tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]]; GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Lanthanum promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; loreclezole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; methylone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; phenylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; phenylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; tetrabromobisphenol A promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]; Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides; alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Anthracenes analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Bicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]]; Bicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]]; Cocaine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; cyclopentaphenanthrene analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]; gamma-Aminobutyric Acid results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]; gamma-Aminobutyric Acid results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]; methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]; Niflumic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]; Niflumic Acid promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Steroids analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; tiotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]]; Topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]; Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]; gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]; Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]
CTD PMID:1712603 PMID:2165521 PMID:8632757 PMID:9316872 PMID:10049148 PMID:10797553 PMID:10987858 PMID:11123204 PMID:11137757 PMID:11156579 PMID:11399263 PMID:11812690 PMID:12939268 PMID:14637376 PMID:15363660 PMID:15588619 PMID:17054655 PMID:18275132 PMID:20819908 PMID:20861069 PMID:21729720 PMID:22547355 PMID:26344803 PMID:27720918 PMID:29038840 PMID:32209479 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 increases expression EXP gamma-Aminobutyric Acid results in increased expression of GABRG3 mRNA CTD PMID:26924987 NCBI chr 1:112,158,525...112,812,267
Ensembl chr 1:112,158,519...112,811,936
JBrowse link
G Gabrq gamma-aminobutyric acid type A receptor subunit theta decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of GABRQ mRNA CTD PMID:26924987 NCBI chr  X:152,852,230...152,869,012
Ensembl chr  X:152,852,506...152,864,975
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 multiple interactions
increases activity
EXP picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABRR3 protein]; Zinc inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABRR3 protein] CTD PMID:10635063 NCBI chr11:43,046,987...43,099,754
Ensembl chr11:43,046,987...43,099,412
JBrowse link
G Gad1 glutamate decarboxylase 1 increases chemical synthesis
decreases expression
ISO
EXP
GAD1 protein results in increased chemical synthesis of gamma-Aminobutyric Acid
gamma-Aminobutyric Acid results in decreased expression of GAD1 mRNA
CTD PMID:15571623 PMID:26924987 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 increases chemical synthesis EXP GAD2 protein results in increased chemical synthesis of gamma-Aminobutyric Acid CTD PMID:12634427 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gast gastrin decreases abundance EXP GAST protein results in decreased abundance of gamma-Aminobutyric Acid CTD PMID:1644166 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP gamma-Aminobutyric Acid results in increased expression of GFAP protein CTD PMID:17845906 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Glul glutamate-ammonia ligase increases expression EXP gamma-Aminobutyric Acid results in increased expression of GLUL mRNA CTD PMID:26924987 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases secretion
multiple interactions
EXP gamma-Aminobutyric Acid results in decreased secretion of GNRH1 protein
gamma-Aminobutyric Acid inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein]
CTD PMID:17845906 PMID:18603625 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:29044621 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 decreases abundance ISO HCN1 gene mutant form results in decreased abundance of gamma-Aminobutyric Acid CTD PMID:19747469 NCBI chr 2:50,099,576...50,499,799
Ensembl chr 2:50,099,576...50,499,799
JBrowse link
G Hcrt hypocretin neuropeptide precursor decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of HCRT mRNA CTD PMID:26924987 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430
JBrowse link
G Hcrtr2 hypocretin receptor 2 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of HCRTR2 mRNA CTD PMID:26924987 NCBI chr 8:83,307,684...83,421,612
Ensembl chr 8:83,307,684...83,421,612
JBrowse link
G Hdc histidine decarboxylase multiple interactions ISO HDC protein affects the reaction [Methamphetamine results in decreased abundance of gamma-Aminobutyric Acid] CTD PMID:12421355 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hoxa10 homeobox A10 decreases expression ISO gamma-Aminobutyric Acid results in decreased expression of HOXA10 mRNA; gamma-Aminobutyric Acid results in decreased expression of HOXA10 protein CTD PMID:32048404 NCBI chr 4:82,285,940...82,295,892
Ensembl chr 4:82,285,528...82,295,470
Ensembl chr 4:82,285,528...82,295,470
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects expression EXP gamma-Aminobutyric Acid affects the expression of HTR1B mRNA CTD PMID:26924987 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of HTR3A mRNA CTD PMID:26924987 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
G Il6 interleukin 6 affects expression
multiple interactions
EXP gamma-Aminobutyric Acid affects the expression of IL6 protein
gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD PMID:24098073 PMID:28456544 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of JUN mRNA CTD PMID:26924987 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects expression EXP gamma-Aminobutyric Acid affects the expression of JUNB mRNA CTD PMID:26924987 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcnip1 potassium voltage-gated channel interacting protein 1 multiple interactions EXP KCNIP1 mRNA promotes the reaction [4-Aminopyridine results in increased abundance of gamma-Aminobutyric Acid] CTD PMID:25917026 NCBI chr10:18,558,128...18,942,677
Ensembl chr10:18,558,128...18,942,540
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO gamma-Aminobutyric Acid results in decreased expression of LIF mRNA; gamma-Aminobutyric Acid results in decreased expression of LIF protein CTD PMID:32048404 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of MAP3K5 protein] CTD PMID:29044621 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects expression EXP gamma-Aminobutyric Acid affects the expression of MYC mRNA CTD PMID:26924987 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncam1 neural cell adhesion molecule 1 affects localization
decreases expression
EXP gamma-Aminobutyric Acid affects the localization of NCAM1 protein modified form
gamma-Aminobutyric Acid results in decreased expression of NCAM1 protein modified form
CTD PMID:17845906 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Npffr1 neuropeptide FF receptor 1 affects expression EXP gamma-Aminobutyric Acid affects the expression of NPFFR1 mRNA CTD PMID:26924987 NCBI chr20:31,214,950...31,248,710
Ensembl chr20:31,234,493...31,245,955
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of NSF mRNA CTD PMID:26924987 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Nts neurotensin multiple interactions
increases secretion
EXP NTS protein inhibits the reaction [Cocaine results in decreased secretion of gamma-Aminobutyric Acid]
NTS protein results in increased secretion of gamma-Aminobutyric Acid
CTD PMID:18252810 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Oprm1 opioid receptor, mu 1 decreases secretion ISO OPRM1 protein mutant form results in decreased secretion of gamma-Aminobutyric Acid CTD PMID:20203187 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of P2RX7 mRNA CTD PMID:26924987 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Postn periostin affects expression EXP gamma-Aminobutyric Acid affects the expression of POSTN mRNA CTD PMID:24098073 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [gamma-Aminobutyric Acid co-treated with Glucose] binds to PPARA protein; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Prlhr prolactin releasing hormone receptor decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of PRLHR mRNA CTD PMID:26924987 NCBI chr 1:281,754,472...281,756,159
Ensembl chr 1:281,754,724...281,756,159
JBrowse link
G Runx2 RUNX family transcription factor 2 affects expression EXP gamma-Aminobutyric Acid affects the expression of RUNX2 mRNA CTD PMID:24098073 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sct secretin multiple interactions
increases secretion
EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [SCT protein results in increased secretion of gamma-Aminobutyric Acid] CTD PMID:15206007 PMID:15963647 NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO gamma-Aminobutyric Acid promotes the reaction [SLC22A7 protein results in increased export of Orotic Acid] CTD PMID:22981274 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc32a1 solute carrier family 32 member 1 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of SLC32A1 mRNA CTD PMID:26924987 NCBI chr 3:155,102,980...155,107,815
Ensembl chr 3:155,103,150...155,107,817
JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of SLC38A1 mRNA CTD PMID:26924987 NCBI chr 7:137,970,555...138,040,098
Ensembl chr 7:137,975,549...138,039,984
JBrowse link
G Slc6a1 solute carrier family 6 member 1 increases export
decreases expression
increases uptake
multiple interactions
ISO
EXP
SLC6A1 results in increased export of gamma-Aminobutyric Acid
gamma-Aminobutyric Acid results in decreased expression of SLC6A1 mRNA
SLC6A1 protein results in increased uptake of gamma-Aminobutyric Acid
Niflumic Acid inhibits the reaction [SLC6A1 protein results in increased uptake of gamma-Aminobutyric Acid]
CTD PMID:15981712 PMID:21748804 PMID:26924987 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link
G Slc6a11 solute carrier family 6 member 11 increases export
decreases expression
multiple interactions
increases uptake
ISO
EXP
SLC6A11 results in increased export of gamma-Aminobutyric Acid
gamma-Aminobutyric Acid results in decreased expression of SLC6A11 mRNA
Flufenamic Acid inhibits the reaction [SLC6A11 protein results in increased uptake of gamma-Aminobutyric Acid]; Niflumic Acid inhibits the reaction [SLC6A11 protein results in increased uptake of gamma-Aminobutyric Acid]; SLC6A11 protein results in increased uptake of [gamma-Aminobutyric Acid co-treated with Sodium co-treated with Chlorides]; Sodium promotes the reaction [SLC6A11 protein results in increased uptake of gamma-Aminobutyric Acid]
CTD PMID:15981712 PMID:21748804 PMID:26924987 NCBI chr 4:146,106,386...146,223,228
Ensembl chr 4:146,106,386...146,223,228
JBrowse link
G Slc6a12 solute carrier family 6 member 12 affects uptake
decreases expression
EXP SLC6A12 protein affects the uptake of gamma-Aminobutyric Acid
gamma-Aminobutyric Acid results in decreased expression of SLC6A12 mRNA
CTD PMID:12634427 PMID:26924987 NCBI chr 4:153,921,199...153,941,333
Ensembl chr 4:153,921,115...153,941,391
JBrowse link
G Slc6a13 solute carrier family 6 member 13 increases export ISO SLC6A13 results in increased export of gamma-Aminobutyric Acid CTD PMID:21748804 NCBI chr 4:153,874,942...153,912,185
Ensembl chr 4:153,874,852...153,912,155
JBrowse link
G Slc8a3 solute carrier family 8 member A3 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of SLC8A3 mRNA CTD PMID:26924987 NCBI chr 6:104,889,500...105,099,408
Ensembl chr 6:104,891,376...105,097,054
JBrowse link
G Sp7 Sp7 transcription factor affects expression EXP gamma-Aminobutyric Acid affects the expression of SP7 mRNA CTD PMID:24098073 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Sparc secreted protein acidic and cysteine rich affects expression EXP gamma-Aminobutyric Acid affects the expression of SPARC mRNA CTD PMID:24098073 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 decreases expression EXP gamma-Aminobutyric Acid results in decreased expression of ST8SIA4 mRNA CTD PMID:17845906 NCBI chr 9:103,117,705...103,207,154
Ensembl chr 9:103,117,506...103,207,190
JBrowse link
G Syn2 synapsin II increases abundance ISO SYN2 mutant form results in increased abundance of gamma-Aminobutyric Acid CTD PMID:18701217 NCBI chr 4:147,037,179...147,195,096
Ensembl chr 4:147,037,179...147,195,096
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:28456544 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
gabapentin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase decreases activity EXP gabapentin results in decreased activity of AADAT protein CTD PMID:16765940 NCBI chr16:32,832,001...32,868,680
Ensembl chr16:32,832,061...32,868,702
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO gabapentin results in decreased activity of ABCB1 protein CTD PMID:18408562 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP gabapentin results in increased expression of AKR7A3 mRNA CTD PMID:17381134 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases activity
multiple interactions
EXP
ISO
gabapentin results in decreased activity of CACNA1A protein
gabapentin promotes the reaction [[omega-Agatoxin IVA results in decreased activity of CACNA1A protein] which results in decreased susceptibility to Potassium Chloride]
CTD PMID:12770949 PMID:12817894 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B decreases activity EXP gabapentin results in decreased activity of CACNA1B protein CTD PMID:12770949 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D multiple interactions EXP CACNA2D1 protein results in increased susceptibility to [gabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]]; gabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:19796812 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions
affects binding
ISO
EXP
[gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Methamphetamine; [gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Potassium Chloride; [gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; gabapentin inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]
CACNA2D1 protein results in increased susceptibility to [gabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]]
gabapentin binds to CACNA2D1 protein
CTD PMID:16380257 PMID:17442347 PMID:17881535 PMID:19796812 PMID:20340177 PMID:21182903 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects activity
affects binding
ISO CACNA2D2 protein affects the activity of gabapentin
gabapentin binds to CACNA2D2 protein
CTD PMID:11687876 PMID:14660671 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions EXP CACNA2D1 protein results in increased susceptibility to [gabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]]; gabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:19796812 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cp ceruloplasmin decreases expression EXP gabapentin results in decreased expression of CP mRNA CTD PMID:17381134 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression EXP gabapentin results in decreased expression of CYP1A1 mRNA CTD PMID:17381134 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression EXP gabapentin results in decreased expression of CYP2E1 mRNA CTD PMID:17381134 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression EXP Gabapentin results in decreased expression of CYP3A23-3A1 mRNA CTD PMID:17381134 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP gabapentin results in decreased expression of CYP4A1 mRNA CTD PMID:17381134 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G F10 coagulation factor X decreases expression EXP gabapentin results in decreased expression of F10 mRNA CTD PMID:17381134 NCBI chr16:81,803,169...81,822,476
Ensembl chr16:81,803,110...81,822,716
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Gabapentin results in decreased expression of G6PC1 mRNA CTD PMID:17381134 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO CGP 71872 inhibits the reaction [gabapentin binds to and results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein]]; gabapentin binds to and results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein] CTD PMID:11125035 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO CGP 71872 inhibits the reaction [Gabapentin binds to and results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein]]; Gabapentin binds to and results in increased activity of [GABBR1 protein alternative form binds to GABBR2 protein] CTD PMID:11125035 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression EXP gabapentin results in decreased expression of GSTA2 mRNA CTD PMID:17381134 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP gabapentin results in increased expression of GSTM1 mRNA CTD PMID:17381134 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP gabapentin results in increased expression of HMOX1 mRNA CTD PMID:17381134 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP gabapentin results in decreased expression of HSP90AA1 mRNA CTD PMID:17381134 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP gabapentin results in increased expression of IGF1 mRNA CTD PMID:17381134 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO gabapentin results in decreased activity of KCNH2 protein CTD PMID:15716081 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases activity EXP gabapentin results in decreased activity of KYAT1 protein CTD PMID:16765940 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Ncl nucleolin increases expression EXP gabapentin results in increased expression of NCL mRNA CTD PMID:17381134 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP gabapentin results in increased expression of NOS2 protein CTD PMID:14511393 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP gabapentin results in increased expression of NQO1 mRNA CTD PMID:17381134 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pnoc prepronociceptin decreases expression ISO gabapentin results in decreased expression of PNOC mRNA CTD PMID:18281898 NCBI chr15:48,805,841...48,833,071
Ensembl chr15:48,805,228...48,833,285
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO gabapentin results in decreased activity of PON1 protein CTD PMID:28032682 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases expression
decreases expression
EXP gabapentin results in increased expression of SLC22A7 mRNA
gabapentin results in decreased expression of SLC22A7 mRNA
CTD PMID:17381134 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases import ISO SLC7A5 protein results in increased import of gabapentin CTD PMID:27818298 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression EXP gabapentin results in increased expression of ST13 mRNA CTD PMID:17381134 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP gabapentin results in decreased expression of SULT1A1 mRNA CTD PMID:17381134 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP gabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:14499429 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tkt transketolase increases expression EXP gabapentin results in increased expression of TKT mRNA CTD PMID:17381134 NCBI chr16:6,609,670...6,634,608
Ensembl chr16:6,609,668...6,634,595
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP gabapentin results in increased expression of TXNRD1 mRNA CTD PMID:17381134 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression EXP gabapentin results in decreased expression of UGDH mRNA CTD PMID:17381134 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP gabapentin results in increased expression of UGT2B1 mRNA CTD PMID:17381134 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
pregabalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions
increases expression
EXP Captopril inhibits the reaction [Pregabalin results in increased expression of ACE protein]; Telmisartan inhibits the reaction [Pregabalin results in increased expression of ACE protein] CTD PMID:31629013 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions
decreases expression
EXP Captopril inhibits the reaction [Pregabalin results in decreased expression of ACE2 protein]; Telmisartan inhibits the reaction [Pregabalin results in decreased expression of ACE2 protein] CTD PMID:31629013 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Adra2a adrenoceptor alpha 2A decreases expression ISO Pregabalin results in decreased expression of ADRA2A mRNA CTD PMID:22489711 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Agt angiotensinogen decreases expression
multiple interactions
EXP Pregabalin results in decreased expression of AGT protein
Captopril inhibits the reaction [Pregabalin results in decreased expression of AGT protein]; Telmisartan inhibits the reaction [Pregabalin results in decreased expression of AGT protein]
CTD PMID:31629013 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression
multiple interactions
EXP Pregabalin results in increased expression of AGTR1 protein
Captopril inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein]; Telmisartan inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein]
CTD PMID:31629013 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C affects localization EXP Pregabalin affects the localization of CACNA1C protein CTD PMID:22949532 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 decreases response to substance
affects response to substance
multiple interactions
affects binding
decreases expression
affects localization
ISO
EXP
CACNA2D1 gene mutant form results in decreased susceptibility to Pregabalin
CACNA2D1 affects the susceptibility to Pregabalin
CACNA2D1 protein affects the susceptibility to and affects the activity of Pregabalin; Pregabalin binds to and affects the activity of CACNA2D1 protein
Pregabalin binds to and affects the activity of CACNA2D1 protein; Pregabalin results in decreased expression of and affects the localization of CACNA2D1 protein
Pregabalin binds to CACNA2D1 protein
Pregabalin results in decreased expression of CACNA2D1 mRNA
Pregabalin affects the localization of CACNA2D1 protein
CTD PMID:16460711 PMID:17088553 PMID:19339603 PMID:22949532 PMID:24133248 PMID:24269977 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Casp3 caspase 3 affects expression EXP Pregabalin affects the expression of CASP3 protein CTD PMID:21394310 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cnr1 cannabinoid receptor 1 affects expression ISO Pregabalin affects the expression of CNR1 mRNA CTD PMID:22017514 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO Pregabalin results in decreased expression of DRD2 mRNA CTD PMID:22489711 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Pregabalin inhibits the reaction [Nitroglycerin results in increased expression of FOS protein] CTD PMID:25290014 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression
multiple interactions
EXP Pregabalin results in decreased expression of MAS1 protein
Captopril inhibits the reaction [Pregabalin results in decreased expression of MAS1 protein]; Telmisartan inhibits the reaction [Pregabalin results in decreased expression of MAS1 protein]
CTD PMID:31629013 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Nppb natriuretic peptide B increases expression
multiple interactions
EXP Pregabalin results in increased expression of NPPB protein
Captopril inhibits the reaction [Pregabalin results in increased expression of NPPB protein]; Telmisartan inhibits the reaction [Pregabalin results in increased expression of NPPB protein]
CTD PMID:31629013 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G P2rx3 purinergic receptor P2X 3 affects expression EXP Pregabalin affects the expression of P2RX3 mRNA; Pregabalin affects the expression of P2RX3 protein CTD PMID:24136739 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions
decreases expression
EXP Captopril inhibits the reaction [Pregabalin results in decreased expression of PRKACA protein]; Telmisartan inhibits the reaction [Pregabalin results in decreased expression of PRKACA protein] CTD PMID:31629013 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Slc1a1 solute carrier family 1 member 1 multiple interactions
increases activity
EXP chelerythrine inhibits the reaction [Pregabalin results in increased activity of SLC1A1 protein]; Staurosporine inhibits the reaction [Pregabalin results in increased activity of SLC1A1 protein]; wortmannin inhibits the reaction [Pregabalin results in increased activity of SLC1A1 protein] CTD PMID:22511482 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Stx1a syntaxin 1A affects response to substance ISO STX1A affects the susceptibility to Pregabalin CTD PMID:24269977 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Pregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:14499429 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Pregabalin results in increased expression of TGFB1 protein CTD PMID:25340254 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase increases expression
affects expression
ISO Pregabalin results in increased expression of TH mRNA
Pregabalin affects the expression of TH mRNA
CTD PMID:22017514 PMID:22489711 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Pregabalin inhibits the reaction [Vincristine results in increased expression of TNF protein] CTD PMID:26102012 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    role 19723
      biological role 19723
        molecular messenger 18303
          neurotransmitter 10804
            gamma-aminobutyric acid 153
              (1S,2S,5S)-2-(4-glutaridylbenzyl)-5-phenylcyclohexan-1-ol 0
              4-(methylamino)butyric acid 0
              4-aminobutanoyl-CoA 0
              N-acyl-gamma-aminobutyric acid + 0
              gabapentin + 39
              gabapentin enacarbil 0
              homocarnosine + 0
              methyl 4-aminobutanoate 0
              pregabalin 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic group 18603
                              organic divalent group 18594
                                organodiyl group 18594
                                  carbonyl group 18507
                                    carbonyl compound 18507
                                      carboxylic acid 18159
                                        monocarboxylic acid 17527
                                          fatty acid 16006
                                            short-chain fatty acid 15695
                                              fatty acid 4:0 7848
                                                butyric acid 6198
                                                  gamma-aminobutyric acid 153
                                                    (1S,2S,5S)-2-(4-glutaridylbenzyl)-5-phenylcyclohexan-1-ol 0
                                                    4-(methylamino)butyric acid 0
                                                    4-aminobutanoyl-CoA 0
                                                    N-acyl-gamma-aminobutyric acid + 0
                                                    gabapentin + 39
                                                    gabapentin enacarbil 0
                                                    homocarnosine + 0
                                                    methyl 4-aminobutanoate 0
                                                    pregabalin 21
paths to the root