|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression |
EXP |
Scopolamine results in decreased expression of ABCB1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 4:26,312,403...26,488,456
|
|
G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Scopolamine results in increased expression of ABCG1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr20:9,128,056...9,184,312
|
|
G |
Ache |
acetylcholinesterase |
multiple interactions increases activity increases response to substance affects response to substance decreases expression decreases activity affects activity increases expression |
ISO EXP |
kangshuai yizhi inhibits the reaction [Scopolamine results in increased activity of ACHE protein] ACHE protein results in increased susceptibility to Scopolamine ACHE affects the susceptibility to Scopolamine 7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in increased expression of ACHE protein]; acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein]; ajoene inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; chong-myung-tang inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; mangiferin inhibits the reaction [Scopolamine results in decreased expression of ACHE protein]; Piracetam inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Plant Extracts affects the reaction [Scopolamine affects the activity of ACHE protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of ACHE mRNA]; polygalacic acid inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; protopanaxadiol inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of ACHE protein] Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]; Canagliflozin inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Galantamine inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; stevioside inhibits the reaction [Scopolamine results in increased activity of ACHE protein]; Vitamin E inhibits the reaction [Scopolamine results in decreased activity of ACHE protein] Scopolamine results in increased expression of ACHE mRNA; Scopolamine results in increased expression of ACHE protein |
CTD |
PMID:11814146 PMID:15301936 PMID:18533140 PMID:18672024 PMID:20673844 PMID:20694781 PMID:20871768 PMID:22426032 PMID:26408985 PMID:26434561 PMID:26926176 PMID:27717698 PMID:28837785 PMID:29133030 PMID:31077737 PMID:32001261 PMID:34371027 More...
|
|
NCBI chr12:25,042,882...25,050,608
|
|
G |
Adora3 |
adenosine A3 receptor |
multiple interactions |
ISO |
[N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine binds to and results in increased activity of ADORA3 protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:12672554 |
|
NCBI chr 2:193,352,759...193,392,946
|
|
G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[AGT protein modified form binds to and results in decreased activity of LNPEP protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:11707427 |
|
NCBI chr19:69,426,540...69,447,017
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
EXP |
Scopolamine results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:27346436 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Apba1 |
amyloid beta precursor protein binding family A member 1 |
increases expression |
EXP |
Scopolamine results in increased expression of APBA1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 1:221,363,769...221,569,496
|
|
G |
Aplp2 |
amyloid beta precursor like protein 2 |
increases expression |
EXP |
Scopolamine results in increased expression of APLP2 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 8:29,599,230...29,662,311
|
|
G |
App |
amyloid beta precursor protein |
decreases cleavage |
ISO |
Scopolamine results in decreased cleavage of APP protein |
CTD |
PMID:16423497 |
|
NCBI chr11:37,506,207...37,724,351
|
|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
decreases expression decreases expression |
EXP ISO |
Scopolamine results in decreased expression of ARC mRNA scopolamine decreases expression of Arc mRNA and protein in cerebral cortex and hippocampus |
CTD RGD |
PMID:17540011 PMID:24012642 |
RGD:401938610 |
NCBI chr 7:108,444,959...108,448,413
|
|
G |
Arg2 |
arginase 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of ARG2 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 6:103,669,001...103,694,375
|
|
G |
Arl4d |
ARF like GTPase 4D |
decreases expression |
EXP |
Scopolamine results in decreased expression of ARL4D mRNA |
CTD |
PMID:17540011 |
|
NCBI chr10:86,592,054...86,602,843
|
|
G |
Avp |
arginine vasopressin |
multiple interactions |
EXP |
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:11553362 |
|
NCBI chr 3:138,246,544...138,248,522
|
|
G |
Avpr1a |
arginine vasopressin receptor 1A |
multiple interactions |
EXP |
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:11553362 |
|
NCBI chr 7:59,999,743...60,003,667
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
Scopolamine results in increased expression of BAX mRNA; Scopolamine results in increased expression of BAX protein dihydroactinidiolide inhibits the reaction [Scopolamine results in increased expression of BAX protein]; Donepezil inhibits the reaction [Scopolamine results in increased expression of BAX protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of BAX mRNA] Galantamine inhibits the reaction [Scopolamine results in increased expression of BAX protein]; intybin inhibits the reaction [Scopolamine results in increased expression of BAX protein] |
CTD |
PMID:17120751 PMID:26434561 PMID:27346436 PMID:34371027 |
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bcat1 |
branched chain amino acid transaminase 1 |
increases expression |
EXP |
Scopolamine results in increased expression of BCAT1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 4:179,695,662...179,777,973
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO EXP |
Scopolamine results in decreased expression of BCL2 mRNA; Scopolamine results in decreased expression of BCL2 protein dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]; Donepezil inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein] Galantamine inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein]; intybin inhibits the reaction [Scopolamine results in decreased expression of BCL2 protein] |
CTD |
PMID:17120751 PMID:26434561 PMID:27346436 PMID:34371027 |
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions decreases expression |
EXP ISO |
Scopolamine inhibits the reaction [Dizocilpine Maleate affects the expression of BDNF mRNA]; Scopolamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA] [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein; [Tacrine co-treated with Scopolamine] results in increased expression of BDNF protein; Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Donepezil inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Melatonin inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]; Plant Extracts inhibits the reaction [Scopolamine results in decreased expression of BDNF mRNA]; Serotonin analog inhibits the reaction [Scopolamine results in decreased expression of BDNF protein]; Tacrine inhibits the reaction [Scopolamine results in decreased expression of BDNF protein] Scopolamine results in decreased expression of BDNF mRNA; Scopolamine results in decreased expression of BDNF protein |
CTD |
PMID:8405262 PMID:8635431 PMID:22096544 PMID:26408985 PMID:26434561 PMID:29476728 PMID:31077737 PMID:34371027 More...
|
|
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Cacna1d |
calcium voltage-gated channel subunit alpha1 D |
increases expression |
EXP |
Scopolamine results in increased expression of CACNA1D mRNA |
CTD |
PMID:12818353 |
|
NCBI chr16:5,227,157...5,521,163
|
|
G |
Camkk2 |
calcium/calmodulin-dependent protein kinase kinase 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of CAMKK2 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr12:39,451,828...39,505,719
|
|
G |
Cartpt |
CART prepropeptide |
decreases expression |
EXP |
Scopolamine results in decreased expression of CARTPT mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 2:32,989,215...32,991,794
|
|
G |
Casp3 |
caspase 3 |
increases expression multiple interactions increases activity increases cleavage |
ISO EXP |
Scopolamine results in increased expression of CASP3 mRNA; Scopolamine results in increased expression of CASP3 protein dihydroactinidiolide inhibits the reaction [Scopolamine results in increased activity of CASP3 protein]; Donepezil inhibits the reaction [Scopolamine results in increased activity of CASP3 protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of CASP3 mRNA] Galantamine inhibits the reaction [Scopolamine results in increased cleavage of CASP3 protein]; intybin inhibits the reaction [Scopolamine results in increased cleavage of CASP3 protein] |
CTD |
PMID:17120751 PMID:26434561 PMID:27346436 PMID:34371027 |
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Cat |
catalase |
multiple interactions decreases activity increases activity |
ISO EXP |
acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; chong-myung-tang inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; Donepezil inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; Piracetam inhibits the reaction [Scopolamine results in increased activity of CAT protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased activity of CAT protein]; Tacrine inhibits the reaction [Scopolamine results in decreased activity of CAT protein] Galantamine inhibits the reaction [Scopolamine results in decreased activity of CAT protein]; intybin inhibits the reaction [Scopolamine results in decreased activity of CAT protein] |
CTD |
PMID:20673844 PMID:27346436 PMID:27717698 PMID:31077737 PMID:34371027 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cd3e |
CD3 epsilon subunit of T-cell receptor complex |
decreases expression |
EXP |
Scopolamine results in decreased expression of CD3E mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 8:54,200,617...54,211,770
|
|
G |
Cdkl4 |
cyclin-dependent kinase-like 4 |
increases expression |
EXP |
Scopolamine results in increased expression of CDKL4 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 6:20,202,047...20,244,821
|
|
G |
Chat |
choline O-acetyltransferase |
decreases activity multiple interactions |
ISO |
Scopolamine results in decreased activity of CHAT protein kangshuai yizhi inhibits the reaction [Scopolamine results in decreased activity of CHAT protein] protopanaxadiol inhibits the reaction [Scopolamine results in decreased activity of CHAT protein]; Serotonin analog inhibits the reaction [Scopolamine results in decreased activity of CHAT protein] |
CTD |
PMID:20694781 PMID:26408985 PMID:29133030 |
|
NCBI chr16:7,657,362...7,717,093
|
|
G |
Chrm1 |
cholinergic receptor, muscarinic 1 |
multiple interactions increases expression decreases expression |
EXP ISO |
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; Canagliflozin affects the reaction [Scopolamine results in decreased expression of CHRM1 protein] 7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in decreased expression of CHRM1 protein]; Plant Extracts inhibits the reaction [Scopolamine results in increased expression of CHRM1 mRNA] |
CTD |
PMID:11553362 PMID:26434561 PMID:28837785 PMID:32001261 |
|
NCBI chr 1:205,567,226...205,583,001
|
|
G |
Chrm4 |
cholinergic receptor, muscarinic 4 |
increases response to substance |
ISO |
CHRM4 protein results in increased susceptibility to Scopolamine |
CTD |
PMID:12729838 |
|
NCBI chr 3:98,349,080...98,356,821
|
|
G |
Chrm5 |
cholinergic receptor, muscarinic 5 |
decreases response to substance |
ISO |
CHRM5 protein results in decreased susceptibility to Scopolamine |
CTD |
PMID:13679217 |
|
NCBI chr 3:99,284,846...99,337,252
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
affects binding multiple interactions |
ISO |
Scopolamine binds to [CHRNA4 protein binds to CHRNB2 protein] Scopolamine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:15733544 |
|
NCBI chr 3:168,136,246...168,157,839
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
affects binding multiple interactions |
ISO |
Scopolamine binds to [CHRNA4 protein binds to CHRNB2 protein] Scopolamine promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:15733544 |
|
NCBI chr 2:175,181,402...175,189,619
|
|
G |
Coch |
cochlin |
decreases expression |
EXP |
Scopolamine results in decreased expression of COCH mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 6:69,031,139...69,045,124
|
|
G |
Coro1b |
coronin 1B |
increases expression |
EXP |
Scopolamine results in increased expression of CORO1B mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 1:201,442,977...201,448,416
|
|
G |
Cox5b |
cytochrome c oxidase subunit 5B |
increases expression |
EXP |
Scopolamine results in increased expression of COX5B mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 9:38,921,980...38,923,806
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
decreases phosphorylation multiple interactions |
ISO |
Scopolamine results in decreased phosphorylation of CREB1 protein acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein]; Serotonin analog inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein]; Tacrine inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] |
CTD |
PMID:26408985 PMID:31077737 |
|
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Cryab |
crystallin, alpha B |
increases expression |
EXP |
Scopolamine results in increased expression of CRYAB mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 8:59,989,885...59,995,532
|
|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions decreases response to substance |
ISO |
IL1RN protein inhibits the reaction [CSF2 protein results in decreased susceptibility to Scopolamine] |
CTD |
PMID:8877002 |
|
NCBI chr10:38,887,692...38,889,673
|
|
G |
Cxcr5 |
C-X-C motif chemokine receptor 5 |
decreases expression |
EXP |
Scopolamine results in decreased expression of CXCR5 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 8:53,738,878...53,756,813
|
|
G |
Ddc |
dopa decarboxylase |
decreases expression |
EXP |
Scopolamine results in decreased expression of DDC mRNA |
CTD |
PMID:17540011 |
|
NCBI chr14:86,378,685...86,469,189
|
|
G |
Dguok |
deoxyguanosine kinase |
increases expression |
EXP |
Scopolamine results in increased expression of DGUOK mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 4:117,544,784...117,572,414
|
|
G |
Dio2 |
iodothyronine deiodinase 2 |
increases expression |
EXP |
Scopolamine results in increased expression of DIO2 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 6:115,396,308...115,410,594
|
|
G |
Dusp5 |
dual specificity phosphatase 5 |
decreases expression |
EXP |
Scopolamine results in decreased expression of DUSP5 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 1:262,543,774...262,557,201
|
|
G |
Dusp6 |
dual specificity phosphatase 6 |
decreases expression |
EXP |
Scopolamine results in decreased expression of DUSP6 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 7:35,979,502...35,983,834
|
|
G |
Egfr |
epidermal growth factor receptor |
decreases expression |
EXP |
Scopolamine results in decreased expression of EGFR mRNA |
CTD |
PMID:12818353 |
|
NCBI chr14:95,378,626...95,551,358
|
|
G |
Egr1 |
early growth response 1 |
multiple interactions decreases expression |
EXP ISO |
[Scopolamine co-treated with 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine] results in increased expression of EGR1 mRNA; Scopolamine affects the reaction [SK&F 82958 results in increased expression of EGR1 mRNA] Scopolamine results in decreased expression of EGR1 mRNA Scopolamine results in decreased expression of EGR1 protein Donepezil inhibits the reaction [Scopolamine results in decreased expression of EGR1 protein]; protopanaxadiol inhibits the reaction [Scopolamine results in decreased expression of EGR1 protein] |
CTD |
PMID:8861055 PMID:17540011 PMID:29133030 |
|
NCBI chr18:26,737,078...26,740,877
|
|
G |
Egr2 |
early growth response 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of EGR2 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr20:21,051,270...21,056,322
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases expression |
EXP |
Scopolamine results in increased expression of EIF2S1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 6:103,405,880...103,430,549
|
|
G |
Eml1 |
EMAP like 1 |
decreases expression |
EXP |
Scopolamine results in decreased expression of EML1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 6:127,283,968...127,457,246
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression increases expression |
EXP ISO |
[Scopolamine co-treated with 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine] results in increased expression of FOS mRNA; Physostigmine inhibits the reaction [Scopolamine promotes the reaction [SK&F 82958 results in increased expression of FOS mRNA]]; Ro4368554 inhibits the reaction [Scopolamine results in increased expression of FOS protein]; Scopolamine affects the reaction [SK&F 82958 results in increased expression of FOS mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine promotes the reaction [SK&F 82958 results in increased expression of FOS mRNA] Scopolamine results in decreased expression of FOS mRNA Scopolamine results in decreased expression of FOS protein Donepezil inhibits the reaction [Scopolamine results in decreased expression of FOS protein]; protopanaxadiol inhibits the reaction [Scopolamine results in decreased expression of FOS protein] |
CTD |
PMID:1393566 PMID:8281324 PMID:8861055 PMID:11337201 PMID:17540011 PMID:17920665 PMID:29133030 More...
|
|
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
increases expression |
EXP |
Scopolamine results in increased expression of GABBR1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr20:1,469,779...1,499,352
|
|
G |
Gap43 |
growth associated protein 43 |
decreases expression multiple interactions |
ISO |
Scopolamine results in decreased expression of GAP43 protein Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of GAP43 protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of GAP43 protein] |
CTD |
PMID:22096544 |
|
NCBI chr11:71,882,131...71,975,799
|
|
G |
Gfap |
glial fibrillary acidic protein |
multiple interactions decreases expression |
ISO |
Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of GFAP mRNA]; Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of GFAP protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of GFAP protein] Scopolamine results in decreased expression of GFAP mRNA; Scopolamine results in decreased expression of GFAP protein |
CTD |
PMID:22096544 |
|
NCBI chr10:88,352,987...88,361,661
|
|
G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
EXP |
Scopolamine results in increased expression of GJB2 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr15:31,260,390...31,278,222
|
|
G |
Gpc3 |
glypican 3 |
decreases expression |
EXP |
Scopolamine results in decreased expression of GPC3 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr X:136,789,770...137,157,598
|
|
G |
Grm4 |
glutamate metabotropic receptor 4 |
multiple interactions |
ISO |
Scopolamine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] |
CTD |
PMID:18171729 |
|
NCBI chr20:5,484,172...5,572,821
|
|
G |
Gsr |
glutathione-disulfide reductase |
decreases activity multiple interactions |
ISO |
Scopolamine results in decreased activity of GSR protein Serotonin analog inhibits the reaction [Scopolamine results in decreased activity of GSR protein]; Tacrine inhibits the reaction [Scopolamine results in decreased activity of GSR protein] |
CTD |
PMID:26408985 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gypc |
glycophorin C |
decreases expression |
EXP |
Scopolamine results in decreased expression of GYPC mRNA |
CTD |
PMID:17540011 |
|
NCBI chr18:24,434,921...24,467,592
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in increased expression of HMOX1 protein] |
CTD |
PMID:32001261 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Homer1 |
homer scaffold protein 1 |
decreases expression |
EXP |
Scopolamine results in decreased expression of HOMER1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 2:26,279,012...26,388,279
|
|
G |
Hrh1 |
histamine receptor H 1 |
multiple interactions |
EXP |
[Histamine binds to and results in increased activity of HRH1 protein] which results in decreased susceptibility to Scopolamine; Pyrilamine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in decreased susceptibility to Scopolamine] |
CTD |
PMID:19215234 |
|
NCBI chr 4:149,120,511...149,204,267
|
|
G |
Hrh2 |
histamine receptor H 2 |
multiple interactions |
EXP |
[[thioperamide results in increased abundance of Histamine] which results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine; Cimetidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in decreased susceptibility to Scopolamine] |
CTD |
PMID:11640976 PMID:19215234 |
|
NCBI chr17:10,366,004...10,407,791
|
|
G |
Hrh3 |
histamine receptor H3 |
multiple interactions |
EXP |
[clobenpropit binds to and results in decreased activity of HRH3 protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:16488453 |
|
NCBI chr 3:167,191,551...167,196,642
|
|
G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
increases expression |
EXP |
Scopolamine results in increased expression of HSPA2 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 6:100,864,172...100,866,946
|
|
G |
Htr1a |
5-hydroxytryptamine receptor 1A |
multiple interactions increases expression |
EXP |
[4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine; N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [[4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine binds to and results in increased activity of HTR1A] which results in decreased susceptibility to Scopolamine] Scopolamine increases expression of Htr1a mRNA in amygdala, hippocampal formation; Scopolamine increases expression of Htr1a protein in amygdala, hippocampal formation |
CTD RGD |
PMID:10578133 PMID:27760517 |
RGD:405850209 |
NCBI chr 2:38,427,169...38,431,733
|
|
G |
Htr2c |
5-hydroxytryptamine receptor 2C |
increases expression |
EXP |
Scopolamine results in increased expression of HTR2C mRNA |
CTD |
PMID:17540011 |
|
NCBI chr X:115,453,190...115,682,325
|
|
G |
Htr6 |
5-hydroxytryptamine receptor 6 |
decreases expression |
EXP |
Scopolamine results in decreased expression of HTR6 mRNA |
CTD |
PMID:19733250 |
|
NCBI chr 5:156,579,901...156,595,147
|
|
G |
Ifng |
interferon gamma |
multiple interactions increases expression |
EXP |
Fatty Acids, Unsaturated deficiency promotes the reaction [Scopolamine results in increased expression of IFNG mRNA] |
CTD |
PMID:21161262 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Il10 |
interleukin 10 |
decreases expression multiple interactions |
ISO |
Scopolamine results in decreased expression of IL10 protein acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein]; polygalacic acid inhibits the reaction [Scopolamine results in decreased expression of IL10 protein]; Tacrine inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] |
CTD |
PMID:26926176 PMID:31077737 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il1a |
interleukin 1 alpha |
decreases response to substance |
ISO |
IL1A protein results in decreased susceptibility to Scopolamine |
CTD |
PMID:8003924 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
ISO EXP |
Scopolamine results in increased expression of IL1B mRNA; Scopolamine results in increased expression of IL1B protein acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein]; polygalacic acid inhibits the reaction [Scopolamine results in increased expression of IL1B protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of IL1B protein]; timosaponin AIII inhibits the reaction [Scopolamine results in increased expression of IL1B protein] Fatty Acids, Unsaturated deficiency promotes the reaction [Scopolamine results in increased expression of IL1B mRNA] |
CTD |
PMID:18357464 PMID:19426756 PMID:21161262 PMID:26926176 PMID:31077737 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
ISO |
IL1RN protein inhibits the reaction [CSF2 protein results in decreased susceptibility to Scopolamine] |
CTD |
PMID:8877002 |
|
NCBI chr 3:27,509,836...27,525,738
|
|
G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
EXP ISO |
Fatty Acids, Unsaturated deficiency promotes the reaction [Scopolamine results in increased expression of IL6 mRNA]; Scopolamine promotes the reaction [Fatty Acids, Unsaturated deficiency results in increased expression of IL6 mRNA] Scopolamine results in increased expression of IL6 mRNA; Scopolamine results in increased expression of IL6 protein acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of IL6 protein] |
CTD |
PMID:18357464 PMID:21161262 PMID:31077737 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
increases expression |
EXP |
Scopolamine results in increased expression of ITPR1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 4:142,743,401...143,066,505
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
EXP ISO |
Physostigmine inhibits the reaction [Scopolamine promotes the reaction [SK&F 82958 results in increased expression of JUN mRNA]]; Scopolamine promotes the reaction [SK&F 82958 results in increased expression of JUN mRNA] Donepezil inhibits the reaction [Scopolamine results in decreased expression of JUN protein]; protopanaxadiol inhibits the reaction [Scopolamine results in decreased expression of JUN protein] |
CTD |
PMID:11337201 PMID:29133030 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
EXP |
Scopolamine results in decreased expression of JUNB mRNA |
CTD |
PMID:17540011 |
|
NCBI chr19:23,176,265...23,178,049
|
|
G |
Kcna4 |
potassium voltage-gated channel subfamily A member 4 |
increases expression |
EXP |
Scopolamine results in increased expression of KCNA4 mRNA |
CTD |
PMID:12579815 |
|
NCBI chr 3:93,756,399...93,778,004
|
|
G |
Kcnb1 |
potassium voltage-gated channel subfamily B member 1 |
increases expression |
EXP |
Scopolamine results in increased expression of KCNB1 mRNA |
CTD |
PMID:12579815 PMID:15567561 |
|
NCBI chr 3:176,239,285...176,332,408
|
|
G |
Kcnd2 |
potassium voltage-gated channel subfamily D member 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of KCND2 mRNA |
CTD |
PMID:12579815 |
|
NCBI chr 4:49,775,812...50,277,746
|
|
G |
Kcnj3 |
potassium inwardly-rectifying channel, subfamily J, member 3 |
multiple interactions |
ISO |
Scopolamine inhibits the reaction [[Carbachol results in increased activity of [GRM4 protein binds to KCNJ3 protein]] which results in increased import of Thallium] |
CTD |
PMID:18171729 |
|
NCBI chr 3:39,944,896...40,106,646
|
|
G |
Klf2 |
KLF transcription factor 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of KLF2 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr16:17,521,107...17,523,739
|
|
G |
Klf4 |
KLF transcription factor 4 |
decreases expression |
EXP |
Scopolamine results in decreased expression of KLF4 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 5:75,074,107...75,079,182
|
|
G |
Lnpep |
leucyl and cystinyl aminopeptidase |
multiple interactions |
ISO |
[AGT protein modified form binds to and results in decreased activity of LNPEP protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:11707427 |
|
NCBI chr 1:66,931,712...67,027,610
|
|
G |
Madd |
MAP-kinase activating death domain |
increases expression |
EXP |
Scopolamine results in increased expression of MADD mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 3:77,114,330...77,157,865
|
|
G |
Map2 |
microtubule-associated protein 2 |
decreases expression multiple interactions |
ISO |
Scopolamine results in decreased expression of MAP2 protein Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of MAP2 protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of MAP2 protein] |
CTD |
PMID:22096544 |
|
NCBI chr 9:75,173,038...75,431,606
|
|
G |
Mapt |
microtubule-associated protein tau |
decreases expression |
EXP |
Scopolamine results in decreased expression of MAPT mRNA |
CTD |
PMID:12818353 |
|
NCBI chr10:89,638,618...89,736,108
|
|
G |
Mbp |
myelin basic protein |
decreases expression multiple interactions |
ISO |
Scopolamine results in decreased expression of MBP protein Melatonin inhibits the reaction [Scopolamine results in decreased expression of MBP protein] |
CTD |
PMID:29476728 |
|
NCBI chr18:75,855,878...75,966,404
|
|
G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
decreases expression |
ISO EXP |
Scopolamine results in decreased expression of MUC5AC protein |
CTD |
PMID:18357464 PMID:21161262 |
|
NCBI chr 1:206,293,717...206,326,006
|
|
G |
Nefh |
neurofilament heavy chain |
multiple interactions decreases expression |
ISO |
Ashwagandha inhibits the reaction [Scopolamine results in decreased expression of NEFH protein]; withanone inhibits the reaction [Scopolamine results in decreased expression of NEFH protein] |
CTD |
PMID:22096544 |
|
NCBI chr14:84,044,428...84,054,413
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions decreases expression |
ISO EXP |
7-fluoro-1,3-diphenylisoquinoline-1-amine inhibits the reaction [Scopolamine results in decreased expression of NFE2L2 protein] Galantamine inhibits the reaction [Scopolamine results in decreased expression of NFE2L2 protein]; intybin inhibits the reaction [Scopolamine results in decreased expression of NFE2L2 protein] |
CTD |
PMID:27346436 PMID:32001261 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Ngf |
nerve growth factor |
decreases response to substance increases response to substance multiple interactions decreases secretion |
EXP ISO |
NGF protein results in decreased susceptibility to Scopolamine NGF protein results in increased susceptibility to Scopolamine Galantamine promotes the reaction [Scopolamine results in decreased secretion of NGF protein]; intybin inhibits the reaction [Scopolamine results in decreased secretion of NGF protein]; Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA] |
CTD |
PMID:1661212 PMID:8635431 PMID:16405025 PMID:27346436 |
|
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression |
ISO |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased expression of NOS2 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] |
CTD |
PMID:26408985 PMID:31077737 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nova1 |
NOVA alternative splicing regulator 1 |
multiple interactions |
EXP |
Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NOVA1 mRNA] |
CTD |
PMID:20470870 |
|
NCBI chr 6:69,506,983...69,632,437
|
|
G |
Nova2 |
NOVA alternative splicing regulator 2 |
multiple interactions |
EXP |
Scopolamine inhibits the reaction [Pilocarpine results in decreased expression of NOVA2 mRNA] |
CTD |
PMID:20470870 |
|
NCBI chr 1:87,700,328...87,741,755
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions decreases expression |
ISO |
Serotonin analog inhibits the reaction [Scopolamine results in decreased expression of NQO1 protein] |
CTD |
PMID:26408985 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nqo2 |
N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
increases expression |
EXP |
Scopolamine results in increased expression of NQO2 mRNA |
CTD |
PMID:20861374 |
|
NCBI chr17:30,909,482...30,938,725
|
|
G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
decreases expression |
EXP |
Scopolamine results in decreased expression of NR1D1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr10:84,224,599...84,231,812
|
|
G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
decreases expression |
EXP |
Scopolamine results in decreased expression of NR4A1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 7:132,368,399...132,389,300
|
|
G |
Ntf3 |
neurotrophin 3 |
multiple interactions |
EXP |
Scopolamine inhibits the reaction [Pilocarpine results in decreased expression of NTF3 mRNA] |
CTD |
PMID:8635431 |
|
NCBI chr 4:158,914,984...158,984,453
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions decreases expression |
EXP ISO |
Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NTRK2 mRNA] [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein; [Tacrine co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein; Melatonin inhibits the reaction [Scopolamine results in decreased expression of NTRK2 protein] |
CTD |
PMID:8635431 PMID:29476728 PMID:31077737 |
|
NCBI chr17:5,560,558...5,875,899
|
|
G |
Ntrk3 |
neurotrophic receptor tyrosine kinase 3 |
multiple interactions |
EXP |
Scopolamine inhibits the reaction [Pilocarpine results in increased expression of NTRK3 mRNA] |
CTD |
PMID:8635431 |
|
NCBI chr 1:141,526,192...141,913,575
|
|
G |
Pdcd4 |
programmed cell death 4 |
increases expression |
EXP |
Scopolamine results in increased expression of PDCD4 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 1:252,921,342...252,944,278
|
|
G |
Pdyn |
prodynorphin |
decreases response to substance increases expression multiple interactions |
ISO EXP |
PDYN protein modified form results in decreased susceptibility to Scopolamine Scopolamine results in increased expression of PDYN mRNA MR 2266 inhibits the reaction [PDYN protein modified form results in decreased susceptibility to Scopolamine] |
CTD |
PMID:7768285 PMID:17540011 |
|
NCBI chr 3:137,354,161...137,366,503
|
|
G |
Penk |
proenkephalin |
multiple interactions |
EXP |
Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] |
CTD |
PMID:7637876 |
|
NCBI chr 5:21,981,381...21,987,074
|
|
G |
Pgam1 |
phosphoglycerate mutase 1 |
decreases expression |
EXP |
Scopolamine results in decreased expression of PGAM1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 1:250,673,152...250,680,762
|
|
G |
Prep |
prolyl endopeptidase |
increases response to substance multiple interactions increases expression |
EXP |
PREP protein results in increased susceptibility to Scopolamine Piracetam inhibits the reaction [Scopolamine results in increased expression of PREP protein] |
CTD |
PMID:17244263 PMID:18318186 |
|
NCBI chr20:48,556,211...48,653,165
|
|
G |
Prkra |
protein activator of interferon induced protein kinase EIF2AK2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of PRKRA mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 3:61,575,447...61,594,393
|
|
G |
Psen2 |
presenilin 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of PSEN2 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr13:94,499,451...94,528,419
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
Scopolamine results in increased expression of PTGS2 protein acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein]; Serotonin analog inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] |
CTD |
PMID:26408985 PMID:31077737 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Rab14 |
RAB14, member RAS oncogene family |
increases expression |
EXP |
Scopolamine results in increased expression of RAB14 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 3:38,899,430...38,920,572
|
|
G |
Rapgef3 |
Rap guanine nucleotide exchange factor 3 |
decreases expression |
EXP |
Scopolamine results in decreased expression of RAPGEF3 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 7:128,875,772...128,898,203
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
mangiferin inhibits the reaction [Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein]; Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein; timosaponin AIII inhibits the reaction [Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein] |
CTD |
PMID:19182383 PMID:19426756 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Rem2 |
RRAD and GEM like GTPase 2 |
decreases expression |
EXP |
Scopolamine results in decreased expression of REM2 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr15:27,933,950...27,938,429
|
|
G |
Rgs7bp |
regulator of G-protein signaling 7 binding protein |
decreases expression |
EXP |
Scopolamine results in decreased expression of RGS7BP mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 2:37,867,698...37,965,587
|
|
G |
Robo3 |
roundabout guidance receptor 3 |
decreases expression |
EXP |
Scopolamine results in decreased expression of ROBO3 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 8:37,133,542...37,151,674
|
|
G |
Rraga |
Ras-related GTP binding A |
increases expression |
EXP |
Scopolamine results in increased expression of RRAGA mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 5:106,159,335...106,160,930
|
|
G |
S100a4 |
S100 calcium-binding protein A4 |
decreases expression |
EXP |
Scopolamine results in decreased expression of S100A4 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 2:178,388,529...178,390,838
|
|
G |
S1pr1 |
sphingosine-1-phosphate receptor 1 |
increases expression |
EXP |
Scopolamine results in increased expression of S1PR1 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 2:206,309,715...206,314,070
|
|
G |
Scamp2 |
secretory carrier membrane protein 2 |
increases expression |
EXP |
Scopolamine results in increased expression of SCAMP2 mRNA |
CTD |
PMID:12818353 |
|
NCBI chr 8:66,861,504...66,888,151
|
|
G |
Sigmar1 |
sigma non-opioid intracellular receptor 1 |
multiple interactions |
ISO |
[2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine; [igmesine binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine |
CTD |
PMID:12028363 |
|
NCBI chr 5:56,904,155...56,907,012
|
|
G |
Slc47a1 |
solute carrier family 47 member 1 |
multiple interactions |
ISO |
Scopolamine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
|
NCBI chr10:46,533,580...46,590,128
|
|
G |
Slc47a2 |
solute carrier family 47 member 2 |
multiple interactions |
ISO |
Scopolamine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:22419765 |
|
NCBI chr10:46,490,262...46,532,954
|
|
G |
Sult1a1 |
sulfotransferase family 1A member 1 |
increases expression |
EXP |
Scopolamine results in increased expression of SULT1A1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 1:190,702,592...190,706,112
|
|
G |
Syp |
synaptophysin |
multiple interactions increases expression decreases expression |
EXP ISO |
cyclo-L-glycyl-L-2-allylproline inhibits the reaction [Scopolamine results in increased expression of SYP protein] Scopolamine results in decreased expression of SYP mRNA dihydroactinidiolide inhibits the reaction [Scopolamine results in decreased expression of SYP mRNA]; Donepezil inhibits the reaction [Scopolamine results in decreased expression of SYP mRNA] |
CTD |
PMID:20188767 PMID:34371027 |
|
NCBI chr X:17,521,348...17,536,449
|
|
G |
Tac1 |
tachykinin, precursor 1 |
decreases response to substance |
EXP |
TAC1 protein modified form results in decreased susceptibility to Scopolamine |
CTD |
PMID:20600432 |
|
NCBI chr 4:36,645,344...36,653,548
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein]; mangiferin inhibits the reaction [Scopolamine results in increased expression of TNF protein]; Tacrine inhibits the reaction [Scopolamine results in increased expression of TNF protein]; timosaponin AIII inhibits the reaction [Scopolamine results in increased expression of TNF protein] Scopolamine results in increased expression of TNF mRNA; Scopolamine results in increased expression of TNF protein |
CTD |
PMID:18357464 PMID:19182383 PMID:19426756 PMID:21161262 PMID:31077737 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tnrc6a |
trinucleotide repeat containing adaptor 6A |
decreases expression |
EXP |
Scopolamine results in decreased expression of TNRC6A mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 1:186,992,457...187,146,764
|
|
G |
Tpd52l1 |
TPD52 like 1 |
increases expression |
EXP |
Scopolamine results in increased expression of TPD52L1 mRNA |
CTD |
PMID:17540011 |
|
NCBI chr 1:27,991,114...28,109,767
|
|
G |
Vgf |
VGF nerve growth factor inducible |
decreases expression |
EXP |
Scopolamine results in decreased expression of VGF mRNA |
CTD |
PMID:17540011 |
|
NCBI chr12:19,637,313...19,645,123
|
|
G |
Vip |
vasoactive intestinal peptide |
decreases response to substance |
EXP |
VIP protein results in decreased susceptibility to Scopolamine |
CTD |
PMID:8208360 |
|
NCBI chr 1:44,470,232...44,478,561
|
|