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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:paralytic shellfish toxin
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Accession:CHEBI:167564 term browser browse the term
Definition:An alkaloid compound that is 2,6-diamino-4-methyl-pyrollo[1,2-c]-purin-10-diol produced by several cyanobacteria and dinoflagellates, which can result in paralytic shellfish poisoning when ingested.
Synonyms:related_synonym: Formula=C9H12N6O2R4;   PSP toxin;   SMILES=[C@@H]1([C@]2([C@@]3(N(C(N1*)=N)CC(C3(O)O)(*)*)NC(N2)=N)[H])C*;   saxitoxins
 xref: PMID:11319121;   PMID:20692275;   PMID:25871287;   PMID:30605564;   PMID:30983320;   PMID:32456077


show annotations for term's descendants           Sort by:
 
neosaxitoxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor multiple interactions ISO neosaxitoxin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; neosaxitoxin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] CTD PMID:32471037 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
saxitoxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects activity		 ISO [Thioctic Acid co-treated with Saxitoxin] affects the activity of ABCB1 protein
Saxitoxin affects the activity of ABCB1 protein		 CTD PMID:29128272 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      biological role 20000
        poison 18475
          toxin 15296
            paralytic shellfish toxin 2
              Decarbamoylgonyautoxin 1 0
              Decarbamoylgonyautoxin III 0
              Gonyautoxin 1 0
              Gonyautoxin 2 0
              Gonyautoxin 5 0
              decarbamoylsaxitoxin 0
              neosaxitoxin 1
              saxitoxin + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic molecule 19809
                              organic cyclic compound 19572
                                organic heterocyclic compound 18799
                                  organic heteropolycyclic compound 18274
                                    organic heterotricyclic compound 15612
                                      pyrrolopurine 2
                                        paralytic shellfish toxin 2
                                          Decarbamoylgonyautoxin 1 0
                                          Decarbamoylgonyautoxin III 0
                                          Gonyautoxin 1 0
                                          Gonyautoxin 2 0
                                          Gonyautoxin 5 0
                                          decarbamoylsaxitoxin 0
                                          neosaxitoxin 1
                                          saxitoxin + 2
paths to the root