Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:6-aminopenicillanic acid
go back to main search page
Accession:CHEBI:16705 term browser browse the term
Definition:A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics.
Synonyms:exact_synonym: 6-amino-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   6-Aminopenicillamine acid;   6-Aminopenicillanate;   6-Apa;   6-Aps;   6beta-aminopenicillanic acid;   Aminopenicillanic acid;   Formula=C8H12N2O3S;   InChI=1S/C8H12N2O3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,9H2,1-2H3,(H,12,13)/t3-,4+,6-/m1/s1;   InChIKey=NGHVIOIJCVXTGV-ALEPSDHESA-N;   Penicin;   Penin;   Phenacyl 6-aminopenicillinate;   SMILES=C([C@H]1C(S[C@@]2([C@@H](C(N12)=O)N)[H])(C)C)(O)=O
 alt_id: CHEBI:20705;   CHEBI:2172
 xref: Beilstein:15080;   Beilstein:959078;   CAS:551-16-6;   Gmelin:1876702;   KEGG:C02954;   PDBeChem:X1E;   PMID:12569987;   PMID:1384868;   PMID:14687482;   PMID:1701026;   PMID:20970923;   PMID:21614893;   PMID:24293403;   PMID:24389703;   PMID:24631718;   PMID:25057428;   PMID:26852849;   PMID:26986755;   PMID:6166603;   Patent:US2941995;   Reaxys:15080;   Wikipedia:6-APA
 cyclic_relationship: is_conjugate_base_of CHEBI:30938;   is_tautomer_of CHEBI:57869


show annotations for term's descendants           Sort by:
 
amoxicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Amoxicillin results in increased expression of AKR1B10 mRNA CTD PMID:28444390 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Aqp5 aquaporin 5 decreases expression EXP Amoxicillin results in decreased expression of AQP5 protein CTD PMID:30031112 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO Amoxicillin results in decreased expression of CXCL10 mRNA CTD PMID:25091725 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression ISO Amoxicillin results in increased expression of CYP11B2 CTD PMID:17822730 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO Amoxicillin results in increased expression of CYP19A1 CTD PMID:17822730 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions
decreases activity
ISO Amoxicillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine]
Amoxicillin results in decreased activity of CYP2C8 protein
CTD PMID:26763401
G Gsr glutathione-disulfide reductase decreases activity ISO Amoxicillin results in decreased activity of GSR protein CTD PMID:32196862 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Amoxicillin results in increased expression of NQO1 mRNA CTD PMID:28444390 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Amoxicillin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Amoxicillin results in increased expression of SRXN1 mRNA CTD PMID:28444390 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
ampicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression ISO Ampicillin results in decreased expression of ABCC3 mRNA CTD PMID:21632981 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Ampicillin CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2 protein CTD PMID:30545405 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acat2l1 acetyl-CoA acetyltransferase 2-like 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACAT2L1 protein CTD PMID:30545405 NCBI chr 1:47,803,822...47,829,012
Ensembl chr 1:47,803,813...47,829,151
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ACE2 protein CTD PMID:30545405 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases expression ISO Ampicillin results in decreased expression of AGER mRNA CTD PMID:24747151 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ahsg alpha-2-HS-glycoprotein multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of AHSG protein CTD PMID:30545405 NCBI chr11:78,117,903...78,145,956 JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression ISO Ampicillin results in decreased expression of AKR1B10 mRNA CTD PMID:21632981 PMID:26198647 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression ISO Ampicillin results in decreased expression of AKR1C2 mRNA CTD PMID:21632981 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOA protein CTD PMID:30545405 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldob aldolase, fructose-bisphosphate B multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ALDOB protein CTD PMID:30545405 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Amot angiomotin increases expression ISO Ampicillin results in increased expression of AMOT mRNA CTD PMID:21632981 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Ampicillin results in increased expression of ANKRD1 mRNA CTD PMID:21632981 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO Ampicillin results in decreased expression of AQP3 mRNA CTD PMID:21632981 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Arg1 arginase 1 increases expression ISO Ampicillin results in increased expression of ARG1 mRNA CTD PMID:21632981 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ARG2 protein CTD PMID:30545405 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Ampicillin results in increased expression of ARHGDIA mRNA CTD PMID:21632981 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ARPC3 protein CTD PMID:30545405 NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651
JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression ISO Ampicillin results in decreased expression of ARRDC3 mRNA CTD PMID:21632981 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO Ampicillin results in decreased expression of ARRDC4 mRNA CTD PMID:21632981 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of ASAH1 protein CTD PMID:30545405 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Ampicillin results in decreased expression of ASNS mRNA CTD PMID:21632981 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP1A1 protein CTD PMID:30545405 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP2A3 protein CTD PMID:30545405 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5J2 protein CTD PMID:30545405 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5H protein CTD PMID:30545405 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ATP5J protein CTD PMID:30545405 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G B3galt5 Beta-1,3-galactosyltransferase 5 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of B3GALT5 protein CTD PMID:30545405 NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance ISO BAX results in increased susceptibility to Ampicillin CTD PMID:15731293 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bpifb2 BPI fold containing family B, member 2 increases expression ISO Ampicillin results in increased expression of BPIFB2 mRNA CTD PMID:21632981 NCBI chr 3:142,356,990...142,377,053
Ensembl chr 3:142,358,051...142,377,044
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression ISO Ampicillin results in increased expression of CA9 mRNA CTD PMID:21632981 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Calr calreticulin increases expression ISO Ampicillin results in increased expression of CALR mRNA CTD PMID:21632981 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Ampicillin results in increased expression of CCN1 mRNA CTD PMID:21632981 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression ISO Ampicillin results in decreased expression of CCPG1 mRNA CTD PMID:21632981 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Cd40 CD40 molecule increases expression ISO Ampicillin results in increased expression of CD40 mRNA CTD PMID:25091725 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Ampicillin results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Chst15 carbohydrate sulfotransferase 15 increases expression ISO Ampicillin results in increased expression of CHST15 mRNA CTD PMID:21632981 NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707
JBrowse link
G Ckb creatine kinase B increases expression ISO Ampicillin results in increased expression of CKB mRNA CTD PMID:21632981 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clca4 chloride channel accessory 4 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLCA4 protein CTD PMID:30545405 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089
JBrowse link
G Cldn7 claudin 7 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CLDN7 protein CTD PMID:30545405 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Clgn calmegin decreases expression ISO Ampicillin results in decreased expression of CLGN mRNA CTD PMID:21632981 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
JBrowse link
G Clic3 chloride intracellular channel 3 increases expression ISO Ampicillin results in increased expression of CLIC3 mRNA CTD PMID:21632981 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CMBL protein CTD PMID:30545405 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cndp2 carnosine dipeptidase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of CNDP2 protein CTD PMID:30545405 NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX5A protein CTD PMID:30545405 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX6B1 protein CTD PMID:30545405 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of COX7A2 protein CTD PMID:30545405 NCBI chr 8:80,716,824...80,720,922 JBrowse link
G Cp ceruloplasmin increases expression ISO Ampicillin results in increased expression of CP mRNA CTD PMID:21632981 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 decreases expression ISO Ampicillin results in decreased expression of CREB3L3 mRNA CTD PMID:21632981 NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of CSF2 protein CTD PMID:31442584 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csta cystatin A decreases expression ISO Ampicillin results in decreased expression of CSTA mRNA CTD PMID:21632981 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
JBrowse link
G Ctsa cathepsin A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CTSA protein CTD PMID:30545405 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Ampicillin results in increased expression of CXCL2 mRNA CTD PMID:24747151 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO Ampicillin results in decreased expression of CYP1A1 mRNA CTD PMID:21632981 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression ISO Ampicillin results in decreased expression of CYP24A1 mRNA CTD PMID:21632981 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2C11 mRNA CTD PMID:30545405 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2D2 mRNA CTD PMID:30545405 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP2E1 mRNA CTD PMID:30545405 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP3A2 mRNA CTD PMID:30545405 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Ampicillin results in increased expression of DKK1 mRNA CTD PMID:21632981 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Ampicillin results in increased expression of DUSP1 mRNA CTD PMID:21632981 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp7 dual specificity phosphatase 7 increases expression ISO Ampicillin results in increased expression of DUSP7 mRNA CTD PMID:21632981 NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
JBrowse link
G Edn1 endothelin 1 increases expression ISO Ampicillin results in increased expression of EDN1 mRNA CTD PMID:21632981 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EPCAM protein CTD PMID:30545405 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression ISO Ampicillin results in decreased expression of ESM1 mRNA CTD PMID:21632981 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of ETFA protein CTD PMID:30545405 NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969
JBrowse link
G Ezr ezrin multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of EZR protein CTD PMID:30545405 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO Ampicillin results in increased expression of FILIP1L mRNA CTD PMID:21632981 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 increases expression ISO Ampicillin results in increased expression of FXYD1 mRNA CTD PMID:21632981 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Ampicillin results in decreased expression of GCLC mRNA CTD PMID:21632981 PMID:26198647 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression
increases expression
ISO Ampicillin results in decreased expression of GCLM mRNA
Ampicillin results in increased expression of GCLM mRNA
CTD PMID:21632981 PMID:22609641 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GFPT2 protein CTD PMID:30545405 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GIPC2 protein CTD PMID:30545405 NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236
JBrowse link
G Gng12 G protein subunit gamma 12 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of GNG12 protein CTD PMID:30545405 NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 decreases expression ISO Ampicillin results in decreased expression of GPAT3 mRNA CTD PMID:21632981 PMID:26198647 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GPX1 protein CTD PMID:30545405 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTA3 mRNA CTD PMID:30545405 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of GSTM2 mRNA CTD PMID:30545405 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of HEXB protein CTD PMID:30545405 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hmgb1 high mobility group box 1 increases expression ISO Ampicillin results in increased expression of HMGB1 protein CTD PMID:24747151 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Ampicillin results in increased expression of HMOX1 mRNA CTD PMID:25091725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HNRNPH2 protein CTD PMID:30545405 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041
JBrowse link
G Hoxd1 homeo box D1 increases expression ISO Ampicillin results in increased expression of HOXD1 mRNA CTD PMID:21632981 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769
JBrowse link
G Hp haptoglobin multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of HP protein CTD PMID:30545405 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Ampicillin results in decreased expression of IFRD1 mRNA CTD PMID:21632981 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Ampicillin results in increased expression of IGFBP3 mRNA CTD PMID:21632981 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ighe immunoglobulin heavy constant epsilon multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of IGHM protein CTD PMID:30545405
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP
ISO
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]
Ampicillin results in increased expression of IL1B mRNA
CTD PMID:21893697 PMID:24747151 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein] CTD PMID:31442584 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO Ampicillin results in decreased expression of JDP2 mRNA CTD PMID:21632981 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Ampicillin results in increased expression of JUND mRNA CTD PMID:21632981 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kng2 kininogen 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAP1 protein CTD PMID:30545405 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Krt16 keratin 16 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of KRT16 protein CTD PMID:30545405 NCBI chr10:85,168,357...85,171,744 JBrowse link
G Lox lysyl oxidase increases expression ISO Ampicillin results in increased expression of LOX mRNA CTD PMID:21632981 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lyz2 lysozyme 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of LYZ2 protein CTD PMID:30545405 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MAPK3 protein CTD PMID:30545405 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Maz MYC associated zinc finger protein increases expression ISO Ampicillin results in increased expression of MAZ mRNA CTD PMID:21632981 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Ampicillin inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:11686837 PMID:11991626 PMID:18306037 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 increases expression ISO Ampicillin results in increased expression of MTSS2 mRNA CTD PMID:21632981 NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507
JBrowse link
G Myh14 myosin heavy chain 14 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of MYH14 protein CTD PMID:30545405 NCBI chr 1:95,096,266...95,158,861
Ensembl chr 1:95,096,266...95,158,836
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFA13 protein CTD PMID:30545405 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of NDUFAB1 protein CTD PMID:30545405 NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Ampicillin inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; Ampicillin inhibits the reaction [Indomethacin results in increased expression of NOS2 mRNA] CTD PMID:11686837 PMID:12568917 PMID:15610444 PMID:16944022 PMID:18306037 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of NPC2 protein CTD PMID:30545405 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Ampicillin results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression ISO Ampicillin results in increased expression of PA2G4 mRNA CTD PMID:21632981 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like decreases expression ISO Ampicillin results in decreased expression of PABPC1L mRNA CTD PMID:21632981 NCBI chr 3:152,692,825...152,725,997
Ensembl chr 3:152,693,700...152,725,997
JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 increases expression ISO Ampicillin results in increased expression of PDP2 mRNA CTD PMID:21632981 NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
JBrowse link
G Pdxk pyridoxal kinase multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PDXK protein CTD PMID:30545405 NCBI chr20:10,210,393...10,231,937
Ensembl chr20:10,210,289...10,232,110
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO Ampicillin results in increased expression of PFKFB3 mRNA CTD PMID:21632981 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Pfn1 profilin 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PFN1 protein CTD PMID:30545405 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgam1 phosphoglycerate mutase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein CTD PMID:30545405 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgc progastricsin increases expression ISO Ampicillin results in increased expression of PGC mRNA CTD PMID:21632981 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Ampicillin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pir pirin increases expression ISO Ampicillin results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Ampicillin results in increased expression of PKM mRNA CTD PMID:21632981 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plppr1 phospholipid phosphatase related 1 increases expression ISO Ampicillin results in increased expression of PLPPR1 mRNA CTD PMID:21632981 NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
JBrowse link
G Pmm2 phosphomannomutase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PMM2 protein CTD PMID:30545405 NCBI chr10:6,961,521...6,982,913
Ensembl chr10:6,961,709...6,983,098
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Ampicillin results in decreased activity of PON1 protein CTD PMID:16880604 PMID:31581362 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CA protein CTD PMID:30545405 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CB protein CTD PMID:30545405 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PPP1CC protein CTD PMID:30545405 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of PSMA3 protein CTD PMID:30545405 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
JBrowse link
G Ptgr1 prostaglandin reductase 1 decreases expression ISO Ampicillin results in decreased expression of PTGR1 mRNA CTD PMID:21632981 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Ampicillin inhibits the reaction [SC 560 results in increased expression of PTGS2 mRNA] CTD PMID:15610444 PMID:21893697 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptms parathymosin increases expression ISO Ampicillin results in increased expression of PTMS mRNA CTD PMID:21632981 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Ralb RAS like proto-oncogene B multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RALB protein CTD PMID:30545405 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RAN protein CTD PMID:30545405 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276
JBrowse link
G Rgcc regulator of cell cycle increases expression ISO Ampicillin results in increased expression of RGCC mRNA CTD PMID:21632981 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G Rida reactive intermediate imine deaminase A homolog multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RIDA protein CTD PMID:30545405 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
JBrowse link
G Rpl30 ribosomal protein L30 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPL30 protein CTD PMID:30545405 NCBI chr 7:65,648,470...65,651,363
Ensembl chr 7:65,645,991...65,651,363
JBrowse link
G Rpn2 ribophorin II multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPN2 protein CTD PMID:30545405 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
JBrowse link
G Rps23 ribosomal protein S23 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS23 protein CTD PMID:30545405 NCBI chr 2:22,079,339...22,080,909
Ensembl chr 2:22,079,302...22,080,918
JBrowse link
G Rps27l ribosomal protein S27-like multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of RPS27L protein CTD PMID:30545405 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G RT1-DMb RT1 class II, locus DMb multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of RT1-DMB protein CTD PMID:30545405 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
JBrowse link
G S100a10 S100 calcium binding protein A10 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A10 protein CTD PMID:30545405 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of S100A11 protein CTD PMID:30545405 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Ampicillin results in increased expression of S100A9 mRNA CTD PMID:24747151 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Samd1 sterile alpha motif domain containing 1 increases expression ISO Ampicillin results in increased expression of SAMD1 mRNA CTD PMID:21632981 NCBI chr19:24,151,136...24,154,475 JBrowse link
G Scarb2 scavenger receptor class B, member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of SCARB2 protein CTD PMID:30545405 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
JBrowse link
G Serpinb6a serpin family B member 6A multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SERPINB6 protein CTD PMID:30545405 NCBI chr17:30,871,428...30,989,703
Ensembl chr17:30,871,468...31,014,427
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 decreases expression ISO Ampicillin results in decreased expression of SGK2 mRNA CTD PMID:21632981 NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SHMT2 protein CTD PMID:30545405 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression ISO Ampicillin results in increased expression of SLC1A2 protein CTD PMID:17138558 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc22a15 solute carrier family 22, member 15 decreases expression ISO Ampicillin results in decreased expression of SLC22A15 mRNA CTD PMID:21632981 NCBI chr 2:189,298,832...189,359,902
Ensembl chr 2:189,298,832...189,358,792
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP Ampicillin binds to and results in decreased activity of SLC25A20 protein; Ampicillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine] CTD PMID:18452908 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Ampicillin results in increased expression of SLC2A3 mRNA CTD PMID:21632981 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Slc3a1 solute carrier family 3 member 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SLC3A1 protein CTD PMID:30545405 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907
JBrowse link
G Slc6a14 solute carrier family 6 member 14 increases expression ISO Ampicillin results in increased expression of SLC6A14 mRNA CTD PMID:21632981 NCBI chr  X:112,314,643...112,375,412
Ensembl chr  X:112,314,691...112,375,096
JBrowse link
G Slc6a8 solute carrier family 6 member 8 increases expression ISO Ampicillin results in increased expression of SLC6A8 mRNA CTD PMID:21632981 NCBI chr  X:151,384,675...151,393,979
Ensembl chr  X:151,384,675...151,393,979
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Ampicillin results in decreased expression of SLC7A11 mRNA CTD PMID:21632981 PMID:26198647 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 increases expression ISO Ampicillin results in increased expression of SLC9A3R2 mRNA CTD PMID:21632981 NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049
JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO Ampicillin results in decreased expression of SMIM14 mRNA CTD PMID:21632981 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of SMPD2 protein CTD PMID:30545405 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441
JBrowse link
G Srxn1 sulfiredoxin 1 decreases expression ISO Ampicillin results in decreased expression of SRXN1 mRNA CTD PMID:21632981 PMID:26198647 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tagln transgelin increases expression ISO Ampicillin results in increased expression of TAGLN mRNA CTD PMID:21632981 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tars1 threonyl-tRNA synthetase 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TARS protein CTD PMID:30545405 NCBI chr 2:60,368,251...60,387,733
Ensembl chr 2:60,367,796...60,387,717
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO Ampicillin results in decreased expression of TIMP1 mRNA CTD PMID:21632981 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TM9SF2 protein CTD PMID:30545405 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TMED10 protein CTD PMID:30545405 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]
[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein]
CTD PMID:21893697 PMID:31442584 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO Ampicillin results in increased expression of TPM4 mRNA CTD PMID:21632981 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Ampicillin results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:47,485,982...47,509,010 JBrowse link
G Ttyh3 tweety family member 3 increases expression ISO Ampicillin results in increased expression of TTYH3 mRNA CTD PMID:21632981 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
JBrowse link
G Tubal3 tubulin, alpha-like 3 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TUBAL3 protein CTD PMID:30545405 NCBI chr17:66,323,733...66,332,423
Ensembl chr17:66,323,733...66,335,355
JBrowse link
G Tubb1 tubulin, beta 1 class VI increases expression ISO Ampicillin results in increased expression of TUBB1 mRNA CTD PMID:21632981 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
JBrowse link
G Tube1 tubulin, epsilon 1 decreases expression ISO Ampicillin results in decreased expression of TUBE1 mRNA CTD PMID:21632981 NCBI chr20:42,552,362...42,570,648
Ensembl chr20:42,552,437...42,570,314
JBrowse link
G Twf1 twinfilin actin-binding protein 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TWF1 protein CTD PMID:30545405 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894
JBrowse link
G Txndc5 thioredoxin domain containing 5 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of TXNDC5 protein CTD PMID:30545405 NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRC1 protein CTD PMID:30545405 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRFS1 protein CTD PMID:30545405 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein multiple interactions EXP [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of UQCRH protein CTD PMID:30545405 NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]] CTD PMID:21893697 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO Ampicillin results in decreased expression of VLDLR mRNA CTD PMID:21632981 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
benzylpenicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases activity
multiple interactions
EXP
ISO
Penicillin G results in increased activity of ABCC2 protein
Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
CTD PMID:12702717 PMID:15904671 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Penicillin G CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of ACACA mRNA
Penicillin G results in increased expression of ACACA mRNA
CTD PMID:27503388 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acly ATP citrate lyase increases expression
multiple interactions
ISO Penicillin G results in increased expression of ACLY mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of ACLY mRNA
CTD PMID:27503388 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Afp alpha-fetoprotein affects expression
decreases expression
ISO Penicillin G affects the expression of AFP mRNA
Penicillin G results in decreased expression of AFP mRNA
CTD PMID:24737281 PMID:25137620 PMID:26272751 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Anxa8 annexin A8 decreases expression ISO Penicillin G results in decreased expression of ANXA8 mRNA CTD PMID:24737281 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Penicillin G results in increased expression of ATF3 mRNA CTD PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CCL2 mRNA
Penicillin G results in increased expression of CCL2 mRNA
CTD PMID:27503388 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CCR2 mRNA CTD PMID:27503388 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd36 CD36 molecule multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CD36 mRNA
Penicillin G results in increased expression of CD36 mRNA
CTD PMID:27503388 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd86 CD86 molecule increases expression ISO Penicillin G results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist increases expression ISO Penicillin G results in increased expression of CER1 mRNA CTD PMID:26272751 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Penicillin G results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CPT1A mRNA CTD PMID:27503388 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CRP mRNA CTD PMID:27503388 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cs citrate synthase multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of CS mRNA
Penicillin G results in increased expression of CS mRNA
CTD PMID:27503388 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Dcn decorin decreases expression ISO Penicillin G results in decreased expression of DCN mRNA CTD PMID:24737281 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Defb1 defensin beta 1 decreases expression
multiple interactions
ISO Penicillin G results in decreased expression of DEFB1 mRNA
[Penicillin G co-treated with Erythromycin] results in decreased expression of DEFB1 mRNA
CTD PMID:27503388 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of DGAT1 mRNA CTD PMID:27503388 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of DGAT2 mRNA CTD PMID:27503388 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of FABP1 mRNA CTD PMID:27503388 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of FASN mRNA
Penicillin G results in increased expression of FASN mRNA
CTD PMID:27503388 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Frzb frizzled-related protein decreases expression ISO Penicillin G results in decreased expression of FRZB mRNA CTD PMID:24737281 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Penicillin G results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression
multiple interactions
ISO Penicillin G results in increased expression of GPAM mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of GPAM mRNA
CTD PMID:27503388 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Hdac7 histone deacetylase 7 increases expression ISO Penicillin G results in increased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of IFNG mRNA
Penicillin G results in increased expression of IFNG mRNA
CTD PMID:27503388 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression ISO Penicillin G results in decreased expression of IGF2 mRNA CTD PMID:24737281 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Penicillin G results in decreased expression of IGFBP5 mRNA CTD PMID:24737281 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il18 interleukin 18 increases expression ISO Penicillin G results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Penicillin G results in increased expression of IL1A mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of IL1A mRNA
CTD PMID:27503388 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Penicillin G results in increased expression of IL1B mRNA CTD PMID:22609641 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of IL6 mRNA CTD PMID:27503388 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Penicillin G results in increased expression of JUN mRNA CTD PMID:26272751 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kdr kinase insert domain receptor increases expression
decreases expression
ISO Penicillin G results in increased expression of KDR mRNA
Penicillin G results in decreased expression of KDR mRNA
CTD PMID:25137620 PMID:26272751 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of LBP mRNA CTD PMID:27503388 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 decreases expression ISO Penicillin G results in decreased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression ISO Penicillin G results in decreased expression of MMP1 mRNA CTD PMID:24737281 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression
multiple interactions
ISO Penicillin G results in increased expression of MTTP mRNA
[Penicillin G co-treated with Erythromycin] results in increased expression of MTTP mRNA
CTD PMID:27503388 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of MUC2 mRNA CTD PMID:27503388 NCBI chr 1:196,796,257...196,831,740 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Penicillin G results in increased expression of MYC mRNA CTD PMID:26272751 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nefm neurofilament medium chain affects expression ISO Penicillin G affects the expression of NEFM mRNA CTD PMID:25137620 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nes nestin increases expression
affects expression
EXP
ISO
Penicillin G results in increased expression of NES protein
Penicillin G affects the expression of NES mRNA
CTD PMID:16137769 PMID:16369854 PMID:25137620 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of NFKB1 mRNA
Penicillin G results in increased expression of NFKB1 mRNA
CTD PMID:27503388 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Penicillin G results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Penicillin G results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pir pirin increases expression ISO Penicillin G results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases expression ISO Penicillin G results in decreased expression of PNPLA6 mRNA CTD PMID:25137620 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Reg3g regenerating family member 3 gamma multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of REG3G mRNA CTD PMID:27503388 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
JBrowse link
G Retnlb resistin like beta multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in decreased expression of RETNLB mRNA CTD PMID:27503388 NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SCD1 mRNA
Penicillin G results in increased expression of SCD1 mRNA
CTD PMID:27503388 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO Penicillin G results in increased expression of SHH mRNA CTD PMID:26272751 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Potassium promotes the reaction [SLC22A12 protein results in increased uptake of Penicillin G] CTD PMID:15284287 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO Penicillin G inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:203,257,374...203,273,848
Ensembl chr 1:203,257,374...203,273,822
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Penicillin G inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:11602689 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases uptake
EXP
ISO
Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Ranitidine]
resveratrol inhibits the reaction [SLC22A8 protein results in increased uptake of Penicillin G]
CTD PMID:10224140 PMID:15319347 PMID:17255469 PMID:27377006 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc27a2 solute carrier family 27 member 2 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SLC27A2 mRNA CTD PMID:27503388 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slco3a1 solute carrier organic anion transporter family, member 3a1 multiple interactions ISO Penicillin G promotes the reaction [SLCO3A1 protein results in increased uptake of simvastatin acid] CTD PMID:28887287 NCBI chr 1:128,115,184...128,387,887
Ensembl chr 1:128,106,228...128,387,925
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of SREBF1 mRNA CTD PMID:27503388 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Penicillin G co-treated with Erythromycin] results in increased expression of TLR4 mRNA CTD PMID:27503388 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO [Penicillin G co-treated with Erythromycin] results in increased expression of TNF mRNA
Penicillin G results in increased expression of TNF mRNA
CTD PMID:27503388 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Penicillin G results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:47,485,982...47,509,010 JBrowse link
G Ttr transthyretin decreases expression ISO Penicillin G results in decreased expression of TTR mRNA CTD PMID:24737281 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Wnt3 Wnt family member 3 increases expression ISO Penicillin G results in increased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr10:88,680,248...88,724,170
Ensembl chr10:88,680,248...88,724,099
JBrowse link
cloxacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO
EXP
Cloxacillin results in decreased activity of ABCB11 protein CTD PMID:15618715 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Cloxacillin results in increased activity of CASP3 protein
[Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Cloxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein]
CTD PMID:30876886 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Cloxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Cloxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Cloxacillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
dicloxacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Dicloxacillin results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
increases expression
ISO AGER protein affects the reaction [Dicloxacillin results in increased expression of GPT protein]
Dicloxacillin results in increased expression of AGER mRNA
CTD PMID:24747151 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression
ISO [Progesterone co-treated with Dicloxacillin] results in increased expression of CXCL2 mRNA
Dicloxacillin results in increased expression of CXCL2 mRNA
CTD PMID:22157104 PMID:24747151 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions
ISO Dicloxacillin results in increased expression of CXCL1 mRNA
Progesterone promotes the reaction [Dicloxacillin results in increased expression of CXCL1 mRNA]
CTD PMID:22157104 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO Dicloxacillin results in increased expression of and results in increased activity of CYP3A4 protein
Dicloxacillin results in increased expression of CYP3A4 mRNA
CTD PMID:18505790 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO AGER protein affects the reaction [Dicloxacillin results in increased expression of GPT protein]; eritoran inhibits the reaction [Dicloxacillin results in increased expression of GPT protein] CTD PMID:24747151 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmgb1 high mobility group box 1 increases expression ISO Dicloxacillin results in increased expression of HMGB1 protein CTD PMID:24747151 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Dicloxacillin results in increased expression of ICAM1 protein CTD PMID:14729754 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Dicloxacillin results in increased expression of IL1B mRNA CTD PMID:24747151 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 increases response to substance
increases expression
ISO IL4 results in increased susceptibility to Dicloxacillin
Dicloxacillin results in increased expression of IL4 protein
CTD PMID:21094227 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Dicloxacillin results in increased expression of NLRP3 mRNA CTD PMID:24747151 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Dicloxacillin results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Dicloxacillin results in increased expression of S100A8 mRNA CTD PMID:24747151 PMID:28138970 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Dicloxacillin results in increased expression of S100A9 mRNA CTD PMID:24747151 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
flucloxacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Floxacillin results in decreased activity of ABCB11 protein
Floxacillin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Floxacillin results in increased expression of AKR1B10 mRNA CTD PMID:28444390 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Floxacillin results in increased activity of CASP3 protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Floxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
CTD PMID:30876886 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Floxacillin results in increased expression of CCL2 mRNA CTD PMID:24652713 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO [Floxacillin co-treated with CpG ODN 1826] results in decreased expression of CD69 protein CTD PMID:30993380 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Floxacillin co-treated with Gentamicins co-treated with Rifampin] results in increased expression of CRP protein CTD PMID:16943303 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Floxacillin results in increased expression of CXCL2 mRNA CTD PMID:24652713 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Floxacillin results in increased expression of CXCL1 mRNA CTD PMID:24652713 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 results in increased metabolism of Floxacillin CTD PMID:11409940 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Faslg Fas ligand multiple interactions ISO [Floxacillin co-treated with CpG ODN 1826] results in decreased expression of FASL protein; FASL protein affects the reaction [[Floxacillin co-treated with CpG ODN 1826] results in increased expression of GPT protein] CTD PMID:30993380 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
ISO [Floxacillin co-treated with alpha-galactosylceramide] results in increased expression of GPT protein; [Floxacillin co-treated with CpG ODN 1826] results in increased expression of GPT protein; FASL protein affects the reaction [[Floxacillin co-treated with CpG ODN 1826] results in increased expression of GPT protein]; IL17A protein promotes the reaction [Floxacillin results in increased expression of GPT protein] CTD PMID:24652713 PMID:30993380 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmgb1 high mobility group box 1 increases secretion
increases expression
ISO Floxacillin results in increased secretion of HMGB1 protein
Floxacillin results in increased expression of HMGB1 protein
CTD PMID:24652713 PMID:28444390 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Il17a interleukin 17A multiple interactions ISO [IL17A protein co-treated with Floxacillin] results in increased expression of MPO protein; IL17A protein promotes the reaction [Floxacillin results in increased expression of GPT protein] CTD PMID:24652713 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO Floxacillin results in increased secretion of IL1A protein CTD PMID:28444390 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
increases expression
ISO Floxacillin results in increased secretion of IL1B protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
Floxacillin results in increased expression of IL1B mRNA
CTD PMID:24652713 PMID:28444390 PMID:30876886 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il5 interleukin 5 increases expression ISO Floxacillin results in increased expression of IL5 mRNA CTD PMID:24652713 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression
ISO Floxacillin results in increased secretion of IL6 protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
Floxacillin results in increased expression of IL6 mRNA
CTD PMID:24652713 PMID:28444390 PMID:30876886 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [IL17A protein co-treated with Floxacillin] results in increased expression of MPO protein CTD PMID:24652713 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Rorc RAR-related orphan receptor C increases expression ISO Floxacillin results in increased expression of RORC mRNA CTD PMID:24652713 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Floxacillin results in increased expression of S100A8 mRNA CTD PMID:24652713 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Floxacillin results in increased expression of S100A9 mRNA CTD PMID:24652713 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Floxacillin results in increased expression of SRXN1 mRNA CTD PMID:28444390 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tbx21 T-box transcription factor 21 decreases expression ISO Floxacillin results in decreased expression of TBX21 mRNA CTD PMID:24652713 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression
ISO Floxacillin results in increased secretion of TNF protein
[Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein]
Floxacillin results in increased expression of TNF mRNA
CTD PMID:24652713 PMID:28444390 PMID:30876886 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Floxacillin results in increased expression of TXNRD1 mRNA CTD PMID:28444390 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
nafcillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity
multiple interactions
ISO Nafcillin results in increased activity of CASP3 protein
[Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [Nafcillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein]
CTD PMID:30876886 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Nafcillin results in increased expression of CYP3A4 mRNA; Nafcillin results in increased expression of CYP3A4 protein CTD PMID:18505790 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL1B protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with IL6 protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Nafcillin results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Nafcillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Nafcillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Nafcillin results in increased activity of CASP3 protein] CTD PMID:30876886 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
phenoxymethylpenicillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D increases expression ISO Penicillin V results in increased expression of CES1 mRNA CTD PMID:22609641 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Penicillin V results in increased expression of CYP3A4 mRNA; Penicillin V results in increased expression of CYP3A4 protein CTD PMID:18505790 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Penicillin V results in increased expression of GCLM mRNA CTD PMID:22609641 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Mir185 microRNA 185 decreases expression EXP Penicillin V results in decreased expression of MIR185 mRNA CTD PMID:22112502 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir296 microRNA 296 decreases expression EXP Penicillin V results in decreased expression of MIR296 mRNA CTD PMID:22112502 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
JBrowse link
G Mir330 microRNA 330 decreases expression EXP Penicillin V results in decreased expression of MIR330 mRNA CTD PMID:22112502 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
JBrowse link
G Mir34c microRNA 34c decreases expression EXP Penicillin V results in decreased expression of MIR34C mRNA CTD PMID:22112502 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
JBrowse link
G Mir433 microRNA 433 decreases expression EXP Penicillin V results in decreased expression of MIR433 mRNA CTD PMID:22112502 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
JBrowse link
G Mir484 microRNA 484 decreases expression EXP Penicillin V results in decreased expression of MIR484 mRNA CTD PMID:22112502 NCBI chr10:887,684...887,760 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Penicillin V results in increased expression of NQO1 mRNA CTD PMID:22609641 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pir pirin increases expression ISO Penicillin V results in increased expression of PIR mRNA CTD PMID:22609641 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO Penicillin V results in increased expression of TRIM16 mRNA CTD PMID:22609641 NCBI chr10:47,485,982...47,509,010 JBrowse link
piperacillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Piperacillin CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
multiple interactions
ISO Piperacillin results in decreased activity of CYP2C8 protein
Piperacillin inhibits the reaction [CYP2C8 protein results in decreased methylation of Aminopyrine]
CTD PMID:26763401
G Ifng interferon gamma increases secretion ISO Piperacillin results in increased secretion of IFNG protein CTD PMID:29644860 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of IL1B mRNA] CTD PMID:16369182 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il22 interleukin 22 increases secretion ISO Piperacillin results in increased secretion of IL22 protein CTD PMID:29644860 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186
JBrowse link
G Mir155 microRNA 155 increases expression ISO Piperacillin results in increased expression of MIR155 mRNA CTD PMID:29644860 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir18a microRNA 18a increases expression ISO Piperacillin results in increased expression of MIR18A mRNA CTD PMID:29644860 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir21 microRNA 21 increases expression ISO Piperacillin results in increased expression of MIR21 mRNA CTD PMID:29644860 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Piperacillin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970
JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Piperacillin affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions EXP Piperacillin binds to and results in decreased activity of SLC25A20 protein; Piperacillin inhibits the reaction [SLC25A20 protein results in increased transport of Carnitine] CTD PMID:18452908 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of TNF mRNA] CTD PMID:16369182 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        aetiopathogenetic role 19044
          allergen 17271
            6-aminopenicillanic acid 263
              6-aminopenicilloyl group + 0
              6-aminopenicilloyl-butylamine 0
              6-formamidopenicillanic acid + 0
              penicillin + 263
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        carboacyl group 17485
                                          univalent carboacyl group 17485
                                            carbamoyl group 17299
                                              carboxamide 17299
                                                lactam 8307
                                                  beta-lactam 795
                                                    beta-lactam antibiotic 780
                                                      penams 263
                                                        penicillanic acids 263
                                                          penicillanic acid 263
                                                            6-aminopenicillanic acid 263
                                                              6-aminopenicilloyl group + 0
                                                              6-aminopenicilloyl-butylamine 0
                                                              6-formamidopenicillanic acid + 0
                                                              penicillin + 263
paths to the root