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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyanamide
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Accession:CHEBI:16698 term browser browse the term
Definition:A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an amino group.
Synonyms:related_synonym: Carbodiimide;   Formula=CH2N2;   H2N-C#N;   InChI=1S/CH2N2/c2-1-3/h2H2;   InChIKey=XZMCDFZZKTWFGF-UHFFFAOYSA-N;   NH2CN;   SMILES=NC#N;   amidocyanogen;   carbamonitrile;   cyanoamine
 alt_id: CHEBI:14036;   CHEBI:23418;   CHEBI:3967;   CHEBI:41585
 xref: CAS:420-04-2;   DrugBank:DB02679;   Gmelin:784;   KEGG:C01566;   KEGG:D00123
 xref_mesh: MESH:D003484
 xref: PDBeChem:CNN;   PMID:15991038;   PMID:17989515;   PMID:24429000;   PMID:24709147;   PPDB:184;   Reaxys:1732569;   UM-BBD_compID:c0597;   Wikipedia:Cyanamide
 cyclic_relationship: is_conjugate_acid_of CHEBI:64302


show annotations for term's descendants           Sort by:
cyanamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide multiple interactions ISO Cyanamide promotes the reaction [[ADH1 protein co-treated with Ethanol] results in increased abundance of Acetaldehyde]; Cyanamide promotes the reaction [[ADH1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde] CTD PMID:7646056 PMID:11981770 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions
decreases activity		 ISO
EXP		 [Cyanamide results in decreased activity of ALDH2 protein] which results in decreased metabolism of Nitroglycerin
Cyanamide affects the reaction [[lead acetate results in increased abundance of Lead] affects the reaction [Ethanol affects the expression of ALDH2 protein]]; Cyanamide affects the reaction [[lead acetate results in increased abundance of Lead] which affects the expression of ALDH2 protein]; Cyanamide affects the reaction [Ethanol affects the expression of ALDH2 protein]		 CTD PMID:14690875 PMID:18272654 PMID:19576883 PMID:31550440 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Avp arginine vasopressin multiple interactions
increases expression		 EXP [Ethanol co-treated with Cyanamide] results in increased expression of AVP mRNA
Cyanamide results in increased expression of AVP mRNA		 CTD PMID:10718921 PMID:10978654 PMID:11139417 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Cyanamide results in increased expression of BAX mRNA CTD PMID:12003908 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [Ethanol co-treated with Cyanamide] results in increased expression of BCL2 mRNA CTD PMID:12003908 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of BMP7 mRNA] CTD PMID:22285649 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of CCND2 mRNA] CTD PMID:22285649 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP [Ethanol co-treated with Cyanamide] results in decreased expression of CDKN1A mRNA CTD PMID:12003908 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of BMP7 mRNA]; Cyanamide inhibits the reaction [CGA protein results in increased expression of CCND2 mRNA]; Cyanamide inhibits the reaction [CGA protein results in increased expression of CYP17A1 mRNA]; Cyanamide inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]; Cyanamide inhibits the reaction [CGA protein results in increased expression of FSHR mRNA]; Cyanamide inhibits the reaction [CGA protein results in increased expression of LHCGR mRNA] CTD PMID:22285649 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP Cyanamide affects the reaction [Ethanol results in decreased expression of CHAT mRNA]; Cyanamide affects the reaction [Ethanol results in decreased expression of CHAT protein] CTD PMID:17045751 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases expression		 EXP [Cyanamide co-treated with Ethanol] results in increased expression of CRH mRNA; [Ethanol co-treated with Cyanamide] results in increased expression of CRH mRNA
Cyanamide results in increased expression of CRH mRNA		 CTD PMID:10718921 PMID:10978654 PMID:11139417 PMID:12217933 PMID:16375214 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO Cyanamide analog binds to and results in decreased activity of CTSK protein CTD PMID:15896958 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA] CTD PMID:22285649 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Cyanamide inhibits the reaction [Ethanol results in decreased phosphorylation of EIF4EBP1 protein] CTD PMID:18317950 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP [Acetaldehyde co-treated with Cyanamide] results in increased expression of FOS protein; Acetaldehyde promotes the reaction [Cyanamide results in increased expression of FOS protein]; candesartan inhibits the reaction [[Acetaldehyde co-treated with Cyanamide] results in increased expression of FOS protein]; candesartan inhibits the reaction [Acetaldehyde promotes the reaction [Cyanamide results in increased expression of FOS protein]] CTD PMID:26298003 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of FSHR mRNA] CTD PMID:22285649 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions EXP Cyanamide inhibits the reaction [Ethanol results in increased expression of IGFBP1 mRNA] CTD PMID:12394292 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO Cyanamide inhibits the reaction [CGA protein results in increased expression of LHCGR mRNA] CTD PMID:22285649 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation		 ISO Cyanamide promotes the reaction [Acetaldehyde results in increased lipidation of MAP1LC3B protein]
Cyanamide results in increased lipidation of MAP1LC3B protein		 CTD PMID:24492484 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mitf melanocyte inducing transcription factor decreases expression ISO Cyanamide results in decreased expression of MITF mRNA CTD PMID:23489423 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP [Cyanamide co-treated with Ethanol] results in increased expression of MYC mRNA CTD PMID:12876071 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
decreases activity		 ISO Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein] CTD PMID:22835378 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP [Ethanol co-treated with Cyanamide] results in increased expression of NPPA mRNA CTD PMID:10905996 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases expression		 EXP [Cyanamide co-treated with Ethanol] results in increased expression of POMC mRNA; [Ethanol co-treated with Cyanamide] results in decreased expression of POMC mRNA; [Ethanol co-treated with Cyanamide] results in increased expression of POMC mRNA
Cyanamide results in increased expression of POMC mRNA		 CTD PMID:10978654 PMID:11139417 PMID:16375214 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP Cyanamide promotes the reaction [Ethanol results in decreased activity of PPARA protein] CTD PMID:11022051 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Cyanamide inhibits the reaction [Ethanol inhibits the reaction [rosiglitazone results in increased activity of PPARG protein]] CTD PMID:17030193 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ren renin multiple interactions EXP [Acetaldehyde co-treated with Cyanamide] results in increased activity of REN protein CTD PMID:26298003 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [Ethanol co-treated with Cyanamide] results in increased expression of TP53 mRNA CTD PMID:12003908 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tyr tyrosinase decreases expression ISO Cyanamide results in decreased expression of TYR mRNA CTD PMID:23489423 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
melamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP melamine results in increased expression of A2M CTD PMID:23052191 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Alb albumin multiple interactions EXP [melamine co-treated with cyanuric acid] results in increased expression of ALB protein CTD PMID:22610612 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of BAD protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of BAD protein]; TGFB1 protein affects the reaction [melamine results in increased expression of BAD protein] CTD PMID:22915474 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of BAX protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of BAX protein]; TGFB1 protein affects the reaction [melamine results in increased expression of BAX protein]
melamine results in decreased expression of BAX protein		 CTD PMID:22915474 PMID:29254411 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression		 ISO melamine results in decreased expression of BCL2 protein
melamine results in increased expression of BCL2 protein		 CTD PMID:22915474 PMID:29254411 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO melamine results in decreased expression of BCL2L1 protein CTD PMID:22915474 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression
increases cleavage		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased cleavage of CASP3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased cleavage of CASP3 protein]; TGFB1 protein affects the reaction [melamine results in increased cleavage of CASP3 protein]
melamine results in decreased expression of CASP3 protein		 CTD PMID:22915474 PMID:29254411 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased cleavage of CASP9 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased cleavage of CASP9 protein]; TGFB1 protein affects the reaction [melamine results in increased cleavage of CASP9 protein] CTD PMID:22915474 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [melamine results in increased expression of CCL2 mRNA]; SN50 peptide inhibits the reaction [melamine results in increased expression of CCL2 mRNA] CTD PMID:22915474 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cd44 CD44 molecule increases expression EXP melamine results in increased expression of CD44; melamine results in increased expression of CD44 protein CTD PMID:23052191 PMID:33211169 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Clu clusterin multiple interactions
increases expression		 EXP [cyanuric acid co-treated with melamine] results in increased expression of CLU mRNA; [melamine co-treated with cyanuric acid] results in increased expression of CLU mRNA; [melamine co-treated with cyanuric acid] results in increased expression of CLU protein
melamine results in increased expression of CLU		 CTD PMID:21784140 PMID:22610612 PMID:23022069 PMID:23052191 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO melamine results in increased activity of CYP19A1 protein CTD PMID:32113805 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of FN1 mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of FN1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of FN1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of FN1 protein]; TGFB1 protein affects the reaction [melamine results in increased expression of FN1 mRNA]; TGFB1 protein affects the reaction [melamine results in increased expression of FN1 protein]
melamine results in increased expression of FN1 mRNA; melamine results in increased expression of FN1 protein		 CTD PMID:22915474 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP melamine results in increased expression of GPNMB CTD PMID:23052191 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression EXP melamine results in decreased expression of GRIN1 protein CTD PMID:28206646 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP melamine results in decreased expression of GRIN2B protein CTD PMID:28206646 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
multiple interactions		 EXP melamine results in increased expression of HAVCR1
[cyanuric acid co-treated with melamine] results in increased expression of HAVCR1 mRNA; [melamine co-treated with cyanuric acid] results in increased expression of HAVCR1 mRNA; [melamine co-treated with cyanuric acid] results in increased expression of HAVCR1 protein		 CTD PMID:21784140 PMID:22610612 PMID:23022069 PMID:23052191 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of IL6 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [melamine results in increased expression of IL6 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [melamine results in increased expression of IL6 mRNA]; SN50 peptide inhibits the reaction [melamine results in increased expression of IL6 mRNA] CTD PMID:22915474 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Krt14 keratin 14 increases expression EXP melamine results in increased expression of KRT14 protein CTD PMID:33211169 NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression		 EXP [cyanuric acid co-treated with melamine] results in increased expression of LCN2 mRNA; [melamine co-treated with cyanuric acid] results in increased expression of LCN2 mRNA
melamine results in increased expression of LCN2		 CTD PMID:21784140 PMID:23022069 PMID:23052191 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldha lactate dehydrogenase A decreases activity ISO melamine results in decreased activity of LDHA protein CTD PMID:29254411 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO melamine results in increased phosphorylation of MAPK1 protein CTD PMID:22915474 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression ISO melamine results in increased expression of MAPK14 mRNA CTD PMID:34842327 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
increases expression		 ISO melamine results in increased phosphorylation of MAPK3 protein
melamine results in increased expression of MAPK3 mRNA		 CTD PMID:22915474 PMID:34842327 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases expression ISO melamine results in increased expression of MAPK9 mRNA CTD PMID:34842327 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation ISO melamine results in increased phosphorylation of NFKBIA protein CTD PMID:22915474 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation ISO melamine results in increased phosphorylation of RELA protein CTD PMID:22915474 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity ISO melamine results in decreased activity of SOD1 protein CTD PMID:29254411 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sord sorbitol dehydrogenase decreases activity ISO melamine results in decreased activity of SORD protein CTD PMID:29254411 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP [cyanuric acid co-treated with melamine] results in increased expression of SPP1 mRNA; [melamine co-treated with cyanuric acid] results in increased expression of SPP1 mRNA; [melamine co-treated with cyanuric acid] results in increased expression of SPP1 protein CTD PMID:21784140 PMID:22610612 PMID:23022069 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Tff3 trefoil factor 3 decreases expression EXP melamine results in decreased expression of TFF3 CTD PMID:23052191 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of TGFB1 mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of TGFB1 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of TGFB1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of TGFB1 protein]; SN50 peptide inhibits the reaction [melamine results in increased expression of TGFB1 mRNA]; SN50 peptide inhibits the reaction [melamine results in increased expression of TGFB1 protein]; TGFB1 protein affects the reaction [melamine results in increased cleavage of CASP3 protein]; TGFB1 protein affects the reaction [melamine results in increased cleavage of CASP9 protein]; TGFB1 protein affects the reaction [melamine results in increased expression of BAD protein]; TGFB1 protein affects the reaction [melamine results in increased expression of BAX protein]; TGFB1 protein affects the reaction [melamine results in increased expression of FN1 mRNA]; TGFB1 protein affects the reaction [melamine results in increased expression of FN1 protein]
melamine results in increased expression of TGFB1 mRNA; melamine results in increased expression of TGFB1 protein		 CTD PMID:22915474 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [cyanuric acid co-treated with melamine] results in increased expression of TIMP1 mRNA; [melamine co-treated with cyanuric acid] results in increased expression of TIMP1 mRNA CTD PMID:21784140 PMID:23022069 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP melamine results in increased expression of TNFRSF12A CTD PMID:23052191 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression		 ISO 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; SB 203580 inhibits the reaction [melamine results in increased expression of VCAM1 mRNA]; SN50 peptide inhibits the reaction [melamine results in increased expression of VCAM1 mRNA] CTD PMID:22915474 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
thiacloprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression		 ISO
EXP		 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of ABCC3 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ABCC3 mRNA
thiacloprid results in increased expression of ABCC3 mRNA		 CTD PMID:32745781 PMID:33426623 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ache acetylcholinesterase decreases activity EXP
ISO		 thiacloprid results in decreased activity of ACHE protein CTD PMID:21251949 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA CTD PMID:32736067 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Alb albumin multiple interactions
decreases expression		 EXP astaxanthine inhibits the reaction [thiacloprid results in decreased expression of ALB protein] CTD PMID:34564187 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
multiple interactions		 ISO
EXP		 thiacloprid results in increased expression of ALDH1A1 mRNA
[thiacloprid co-treated with enilconazole] results in decreased expression of ALDH1A1 mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of ALDH1A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of ALDH1A1 mRNA		 CTD PMID:32201337 PMID:33426623 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Atg5 autophagy related 5 decreases expression ISO thiacloprid results in decreased expression of ATG5 mRNA; thiacloprid results in decreased expression of ATG5 protein CTD PMID:37468076 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Cat catalase decreases activity
decreases expression
multiple interactions		 EXP thiacloprid results in decreased activity of CAT protein
thiacloprid results in decreased expression of CAT mRNA
astaxanthine inhibits the reaction [thiacloprid results in decreased activity of CAT protein]; Polysaccharides inhibits the reaction [thiacloprid results in decreased activity of CAT protein]; Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of CAT mRNA]		 CTD PMID:28692354 PMID:34564187 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA CTD PMID:32736067 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [clothianidin co-treated with thiacloprid] results in increased expression of CES2 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CES2 protein CTD PMID:32201337 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP thiacloprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]; thiacloprid results in increased activity of [NACHRALPHA1 protein co-treated with CHRNB2 protein] CTD PMID:16981889 PMID:25459289 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA CTD PMID:32736067 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO thiacloprid results in decreased expression of CREM mRNA; thiacloprid results in decreased expression of CREM protein CTD PMID:37468076 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO thiacloprid results in increased expression of CYBB mRNA CTD PMID:32201337 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO thiacloprid results in decreased expression of CYP11A1 mRNA CTD PMID:37468076 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
affects expression		 ISO thiacloprid results in increased activity of CYP19A1 protein
thiacloprid results in increased expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [thiacloprid affects the expression of CYP19A1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [thiacloprid affects the expression of CYP19A1 mRNA]		 CTD PMID:26464060 PMID:28750898 PMID:29701941 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO thiacloprid results in increased expression of CYP1A1 mRNA; thiacloprid results in increased expression of CYP1A1 protein CTD PMID:21784029 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP1A2 mRNA; thiacloprid results in increased expression of CYP1A2 protein
[enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP1A2 mRNA		 CTD PMID:21784029 PMID:32201337 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions		 EXP thiacloprid results in increased expression of CYP2B2 mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of CYP2B2 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B2 mRNA		 CTD PMID:33426623 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression		 ISO [clothianidin co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B6 protein; [enilconazole co-treated with thiacloprid] results in increased expression of CYP2B9 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP2B6 mRNA
thiacloprid results in increased expression of CYP2B6 mRNA
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA		 CTD PMID:32201337 PMID:32736067 PMID:32745781 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2C55 mRNA CTD PMID:32736067 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression
decreases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP2C19 mRNA
thiacloprid results in decreased expression of CYP2C19 protein
[Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA		 CTD PMID:32194361 PMID:32201337 PMID:32745781 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions		 ISO thiacloprid results in decreased expression of CYP2E1 mRNA
[clothianidin co-treated with thiacloprid] results in increased expression of CYP2E1 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with clothianidin] results in decreased expression of CYP2E1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP2E1 mRNA		 CTD PMID:32201337 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP3A4 mRNA; thiacloprid results in increased expression of CYP3A4 protein
[clothianidin co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP3A4 mRNA; [enilconazole co-treated with thiacloprid] results in increased expression of CYP3A4 protein; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A4 mRNA		 CTD PMID:32201337 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression		 EXP [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A23-3A1 mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of CYP3A23-3A1 mRNA
thiacloprid results in increased expression of CYP3A23-3A1 mRNA		 CTD PMID:33426623 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions		 ISO thiacloprid results in increased expression of CYP3A5 mRNA
[enilconazole co-treated with thiacloprid] results in increased expression of CYP3A5 protein; [thiacloprid co-treated with clothianidin] results in increased expression of CYP3A5 mRNA		 CTD PMID:32201337 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions		 ISO
EXP		 thiacloprid results in decreased expression of CYP7A1 protein
[thiacloprid co-treated with clothianidin] results in decreased expression of CYP7A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of CYP7A1 mRNA
thiacloprid results in decreased expression of CYP7A1 mRNA		 CTD PMID:32194361 PMID:33426623 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO thiacloprid results in decreased expression of DDX4 mRNA; thiacloprid results in decreased expression of DDX4 protein CTD PMID:37468076 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA CTD PMID:32745781 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA CTD PMID:32736067 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061 		JBrowse link
G Eln elastin multiple interactions
decreases expression		 EXP [thiacloprid co-treated with clothianidin] results in decreased expression of ELN mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of ELN mRNA
thiacloprid results in decreased expression of ELN mRNA		 CTD PMID:33426623 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein CTD PMID:32736067 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
multiple interactions		 EXP thiacloprid results in increased expression of GPT protein
astaxanthine inhibits the reaction [thiacloprid results in increased expression of GPT protein]; Polysaccharides inhibits the reaction [thiacloprid results in increased expression of GPT protein]		 CTD PMID:31328355 PMID:34564187 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression		 EXP Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of GPX1 mRNA] CTD PMID:28692354 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression		 EXP astaxanthine inhibits the reaction [thiacloprid results in increased expression of HMGB1 mRNA] CTD PMID:34564187 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA CTD PMID:32745781 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions		 EXP thiacloprid results in increased expression of IL10 protein
astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL10 protein]		 CTD PMID:34564187 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions		 EXP thiacloprid results in increased expression of IL1B protein
astaxanthine inhibits the reaction [thiacloprid results in increased expression of IL1B protein]		 CTD PMID:34564187 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression EXP thiacloprid results in increased expression of IL6 protein CTD PMID:34564187 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of INS1 protein CTD PMID:32745781 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ky kyphoscoliosis peptidase decreases expression
multiple interactions		 EXP thiacloprid results in decreased expression of KY mRNA
[thiacloprid co-treated with clothianidin] results in decreased expression of KY mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of KY mRNA		 CTD PMID:33426623 NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024 		JBrowse link
G Megf11 multiple EGF-like-domains 11 decreases expression
multiple interactions		 EXP thiacloprid results in decreased expression of MEGF11 mRNA
[thiacloprid co-treated with clothianidin] results in decreased expression of MEGF11 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of MEGF11 mRNA		 CTD PMID:33426623 NCBI chr 8:64,892,312...65,218,984
Ensembl chr 8:64,892,387...65,216,061 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO thiacloprid results in decreased expression of MKI67 mRNA; thiacloprid results in decreased expression of MKI67 protein CTD PMID:37468076 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mme membrane metallo-endopeptidase increases expression
multiple interactions		 EXP thiacloprid results in increased expression of MME mRNA
[thiacloprid co-treated with clothianidin] results in increased expression of MME mRNA; [thiacloprid co-treated with enilconazole] results in increased expression of MME mRNA		 CTD PMID:33426623 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP thiacloprid results in increased expression of NOS2 mRNA
astaxanthine inhibits the reaction [thiacloprid results in increased expression of NOS2 mRNA]		 CTD PMID:34564187 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] CTD PMID:29950287 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein CTD PMID:32736067 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO thiacloprid results in increased expression of POR mRNA CTD PMID:32201337 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA CTD PMID:32745781 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO thiacloprid metabolite results in increased activity of SLC22A1 protein; thiacloprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO thiacloprid metabolite results in decreased activity of SLC22A2 protein; thiacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO thiacloprid metabolite results in decreased activity of SLC22A8 protein; thiacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 decreases expression
multiple interactions		 EXP thiacloprid results in decreased expression of SLC6A1 mRNA
[thiacloprid co-treated with clothianidin] results in decreased expression of SLC6A1 mRNA; [thiacloprid co-treated with enilconazole] results in decreased expression of SLC6A1 mRNA		 CTD PMID:33426623 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression		 EXP Polysaccharides inhibits the reaction [thiacloprid results in decreased expression of SOD1 mRNA] CTD PMID:28692354 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO thiacloprid results in decreased expression of STAR mRNA CTD PMID:37468076 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA CTD PMID:32745781 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO thiacloprid results in decreased expression of SYCP3 mRNA; thiacloprid results in decreased expression of SYCP3 protein CTD PMID:37468076 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511 		JBrowse link
G Thrsp thyroid hormone responsive multiple interactions ISO [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] CTD PMID:32745781 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      group 19878
        pseudohalo group 4581
          cyano group 4581
            nitrile 4581
              cyanamide 117
                (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[4-(hydroxymethyl)benzyl]-1,3-diazepan-2-ylidenecyanamide 0
                melamine + 35
                thiacloprid + 59
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            one-carbon compound 17897
                              hydrogen cyanide 4796
                                cyanides 4779
                                  nitrile 4581
                                    cyanamide 117
                                      (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[4-(hydroxymethyl)benzyl]-1,3-diazepan-2-ylidenecyanamide 0
                                      melamine + 35
                                      thiacloprid + 59
paths to the root