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ONTOLOGY REPORT - ANNOTATIONS


Term:albendazole
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Accession:CHEBI:16664 term browser browse the term
Definition:A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations.
Synonyms:exact_synonym: methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate
 related_synonym: (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester;   5-(propylthio)-2-carbomethoxyaminobenzimidazole;   Albenza;   Eskazole;   Formula=C12H15N3O2S;   InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16);   InChIKey=HXHWSAZORRCQMX-UHFFFAOYSA-N;   O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate;   Proftril;   SMILES=CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1;   Valbazen;   Zentel
 alt_id: CHEBI:13751;   CHEBI:22286;   CHEBI:2545
 xref: Beilstein:752696 "Beilstein";   CAS:54965-21-8 "ChemIDplus";   CAS:54965-21-8 "KEGG COMPOUND";   DrugBank:DB00518;   Drug_Central:103 "DrugCentral";   HMDB:HMDB0014659;   KEGG:C01779;   KEGG:D00134;   LINCS:LSM-3782
 xref_mesh: MESH:D015766
 xref: MetaCyc:ALBENDAZOLE;   PMID:22152396 "Europe PMC";   PMID:24403707 "Europe PMC";   PMID:24411094 "Europe PMC";   Pesticides:albendazole "Alan Wood's Pesticides";   Reaxys:752696 "Reaxys";   VSDB:895;   Wikipedia:Albendazole


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albendazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy7 adenylate cyclase 7 JBrowse link 19 19,702,307 19,762,973 RGD:6480464
G Arl4c ADP ribosylation factor like GTPase 4C JBrowse link 9 95,783,651 95,787,092 RGD:6480464
G Bag3 Bcl2-associated athanogene 3 JBrowse link 1 199,941,258 199,965,191 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:6480464
G Cct3 chaperonin containing TCP1 subunit 3 JBrowse link 2 187,669,051 187,693,610 RGD:6480464
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 JBrowse link 19 24,747,178 24,750,919 RGD:6480464
G Dpysl2 dihydropyrimidinase-like 2 JBrowse link 15 43,475,640 43,581,725 RGD:6480464
G Gem GTP binding protein overexpressed in skeletal muscle JBrowse link 5 25,339,479 25,353,661 RGD:6480464
G Gpr183 G protein-coupled receptor 183 JBrowse link 15 108,364,701 108,376,221 RGD:6480464
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 JBrowse link 6 135,107,262 135,112,793 RGD:6480464
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:6480464
G Hspa4 heat shock protein family A (Hsp70) member 4 JBrowse link 10 38,601,624 38,642,397 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:6480464
G Hspe1 heat shock protein family E (Hsp10) member 1 JBrowse link 9 61,691,246 61,724,948 RGD:6480464
G Hsph1 heat shock protein family H (Hsp110) member 1 JBrowse link 12 6,322,685 6,341,898 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:6480464
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:6480464
G Map3k8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 17 56,109,403 56,129,925 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Ppid peptidylprolyl isomerase D JBrowse link 2 178,354,830 178,366,843 RGD:6480464
G Ppif peptidylprolyl isomerase F JBrowse link 16 1,979,191 1,985,912 RGD:6480464
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:6480464
G RT1-DMb RT1 class II, locus DMb JBrowse link 20 3,945,383 3,952,838 RGD:6480464
G Skap2 src kinase associated phosphoprotein 2 JBrowse link 4 81,816,778 81,968,832 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:6480464
G St13 ST13, Hsp70 interacting protein JBrowse link 7 122,585,770 122,635,731 RGD:6480464
G Tcp1 t-complex 1 JBrowse link 1 48,025,664 48,033,343 RGD:6480464
G Tgif1 TGFB-induced factor homeobox 1 JBrowse link 9 119,181,079 119,190,698 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tsc22d1 TSC22 domain family, member 1 JBrowse link 15 58,554,358 58,658,156 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
albendazole S-oxide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        pharmacological role 18695
          tubulin modulator 2482
            albendazole 45
              albendazole S-oxide + 2
              hydroxyalbendazole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic ester 13956
                                        carbamate ester 7334
                                          carbamate fungicide 147
                                            benzimidazolylcarbamate fungicide 128
                                              albendazole 45
                                                albendazole S-oxide + 2
                                                hydroxyalbendazole 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.