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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Hydroxymephenytoin
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Accession:CHEBI:166516 term browser browse the term
Synonyms:exact_synonym: 5-ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione
 related_synonym: Formula=C12H14N2O3;   InChI=1S/C12H14N2O3/c1-3-12(8-4-6-9(15)7-5-8)10(16)14(2)11(17)13-12/h4-7,15H,3H2,1-2H3,(H,13,17);   InChIKey=OQPLORUDZLXXPD-UHFFFAOYSA-N;   SMILES=O=C1N(C(=O)NC1(CC)C2=CC=C(O)C=C2)C
 xref: CAS:61837-65-8;   Chemspider:106722;   HMDB:HMDB0060968
 xref_mesh: MESH:C025687


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Hydroxymephenytoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases chemical synthesis
multiple interactions		 ISO CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin
[CYP2C19 protein results in increased hydroxylation of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin; [CYP2C19 protein results in increased metabolism of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin; Fluoxetine inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]		 CTD PMID:12401345 PMID:15155557 PMID:21915887 PMID:23850985 PMID:25084468 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19851
      atom 19851
        nonmetal atom 19780
          nitrogen atom 18968
            nitrogen molecular entity 18968
              organonitrogen compound 18820
                organonitrogen heterocyclic compound 18163
                  diazolidine 1031
                    imidazolidines 1021
                      imidazolidinone 615
                        imidazolidine-2,4-dione 480
                          Hydroxymephenytoin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    p-block element atom 19797
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            organic molecule 19685
                              organic cyclic compound 19496
                                organic heterocyclic compound 18871
                                  organic heteromonocyclic compound 17803
                                    diazolidine 1031
                                      imidazolidines 1021
                                        imidazolidinone 615
                                          imidazolidine-2,4-dione 480
                                            Hydroxymephenytoin 1
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