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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:raffinose
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Accession:CHEBI:16634 term browser browse the term
Definition:A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.
Synonyms:exact_synonym: beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside
 related_synonym: 6G-alpha-D-galactosylsucrose;   Formula=C18H32O16;   Gossypose;   InChI=1S/C18H32O16/c19-1-5-8(22)11(25)13(27)16(31-5)30-3-7-9(23)12(26)14(28)17(32-7)34-18(4-21)15(29)10(24)6(2-20)33-18/h5-17,19-29H,1-4H2/t5-,6-,7-,8+,9-,10-,11+,12+,13-,14-,15+,16+,17-,18+/m1/s1;   InChIKey=MUPFEKGTMRGPLJ-ZQSKZDJDSA-N;   Melitose;   Melitriose;   SMILES=OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@]3(CO)O[C@H](CO)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O;   alpha-D-Galp-(1->6)-alpha-D-Glcp-(1<->2)-beta-D-Fruf;   alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranosyl beta-D-fructofuranoside;   rafinose;   raflinose
 alt_id: CHEBI:15015;   CHEBI:26521;   CHEBI:49843;   CHEBI:8771
 xref: CAS:512-69-6;   HMDB:HMDB0003213;   KEGG:C00492;   KEGG:G00249;   KNApSAcK:C00001145
 xref_mesh: MESH:D011887
 xref: MetaCyc:CPD-1099;   PDBeChem:RAF;   PMID:23317449;   PMID:23879777;   PMID:23882273;   PMID:24001862;   PMID:24354450;   PMID:24360500;   Reaxys:99543;   Wikipedia:Raffinose



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raffinose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Raffinose results in decreased expression of ACACA mRNA CTD PMID:29458019 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Raffinose results in increased expression of ACOX1 mRNA CTD PMID:29458019 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases secretion ISO Raffinose results in increased secretion of ADIPOQ protein CTD PMID:29458019 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO
EXP
Raffinose results in increased phosphorylation of AKT1 protein CTD PMID:29458019 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Raffinose results in decreased expression of FASN mRNA CTD PMID:29458019 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO
EXP
Raffinose results in increased phosphorylation of GSK3B protein CTD PMID:29458019 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Insr insulin receptor increases phosphorylation EXP
ISO
Raffinose results in increased phosphorylation of INSR protein CTD PMID:29458019 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO Raffinose results in increased expression of PPARA mRNA CTD PMID:29458019 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP
ISO
Raffinose results in increased expression of SLC2A4 protein CTD PMID:29458019 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
verbascose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein] CTD PMID:33130239 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            eukaryotic metabolite 19033
              plant metabolite 17450
                raffinose 13
                  1(F)-alpha-D-galactosylraffinose 0
                  stachyose + 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  carbohydrates and carbohydrate derivatives 12342
                                    carbohydrate 12342
                                      oligosaccharide 573
                                        trisaccharide 159
                                          raffinose 13
                                            1(F)-alpha-D-galactosylraffinose 0
                                            stachyose + 3
paths to the root