Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:raffinose
go back to main search page
Accession:CHEBI:16634 term browser browse the term
Definition:A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.
Synonyms:exact_synonym: beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside
 related_synonym: 6G-alpha-D-galactosylsucrose;   Formula=C18H32O16;   Gossypose;   InChI=1S/C18H32O16/c19-1-5-8(22)11(25)13(27)16(31-5)30-3-7-9(23)12(26)14(28)17(32-7)34-18(4-21)15(29)10(24)6(2-20)33-18/h5-17,19-29H,1-4H2/t5-,6-,7-,8+,9-,10-,11+,12+,13-,14-,15+,16+,17-,18+/m1/s1;   InChIKey=MUPFEKGTMRGPLJ-ZQSKZDJDSA-N;   Melitose;   Melitriose;   SMILES=OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@]3(CO)O[C@H](CO)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O;   alpha-D-Galp-(1->6)-alpha-D-Glcp-(1<->2)-beta-D-Fruf;   alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranosyl beta-D-fructofuranoside;   rafinose;   raflinose
 alt_id: CHEBI:15015;   CHEBI:26521;   CHEBI:49843;   CHEBI:8771
 xref: CAS:512-69-6;   HMDB:HMDB0003213;   KEGG:C00492;   KEGG:G00249;   KNApSAcK:C00001145
 xref_mesh: MESH:D011887
 xref: MetaCyc:CPD-1099;   PDBeChem:RAF;   PMID:23317449;   PMID:23879777;   PMID:23882273;   PMID:24001862;   PMID:24354450;   PMID:24360500;   Reaxys:99543;   Wikipedia:Raffinose



show annotations for term's descendants           Sort by:
raffinose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Raffinose results in decreased expression of ACACA mRNA CTD PMID:29458019 NCBI chr10:69,511,627...69,773,888 JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Raffinose results in increased expression of ACOX1 mRNA CTD PMID:29458019 NCBI chr10:101,905,083...101,930,136 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases secretion ISO Raffinose results in increased secretion of ADIPOQ protein CTD PMID:29458019 NCBI chr11:91,226,524...91,240,244 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO
EXP
Raffinose results in increased phosphorylation of AKT1 protein CTD PMID:29458019 NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Fasn fatty acid synthase decreases expression ISO Raffinose results in decreased expression of FASN mRNA CTD PMID:29458019 NCBI chr10:106,570,415...106,588,581 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO
EXP
Raffinose results in increased phosphorylation of GSK3B protein CTD PMID:29458019 NCBI chr11:76,004,502...76,154,665 JBrowse link
G Ins1 insulin 1 multiple interactions EXP
ISO
Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]
Genistein inhibits the reaction [Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]; Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Wortmannin inhibits the reaction [Raffinose promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]]
CTD PMID:29458019 NCBI chr 1:261,186,119...261,186,686 JBrowse link
G Insr insulin receptor increases phosphorylation EXP
ISO
Raffinose results in increased phosphorylation of INSR protein CTD PMID:29458019 NCBI chr12:5,991,135...6,129,275 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO Raffinose results in increased expression of PPARA mRNA CTD PMID:29458019 NCBI chr 7:118,712,261...118,780,723 JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP
ISO
Raffinose results in increased expression of SLC2A4 protein CTD PMID:29458019 NCBI chr10:55,164,721...55,170,289 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 NCBI chr10:45,507,152...45,529,164 JBrowse link
verbascose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Gallic Acid co-treated with Butyric Acid co-treated with verbascose] affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein]; verbascose affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of IL1B protein] CTD PMID:33130239 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO verbascose promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:33130239 NCBI chr20:3,626,685...3,629,303 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19869
      biological role 19867
        biochemical role 19577
          metabolite 19563
            eukaryotic metabolite 19389
              plant metabolite 18007
                raffinose 14
                  1(F)-alpha-D-galactosylraffinose 0
                  stachyose + 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19535
                              organochalcogen compound 19296
                                organooxygen compound 19213
                                  carbohydrates and carbohydrate derivatives 15318
                                    carbohydrate 15318
                                      oligosaccharide 633
                                        trisaccharide 177
                                          raffinose 14
                                            1(F)-alpha-D-galactosylraffinose 0
                                            stachyose + 3
paths to the root