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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:raffinose
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Accession:CHEBI:16634 term browser browse the term
Definition:A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.
Synonyms:exact_synonym: beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside
 related_synonym: 6G-alpha-D-galactosylsucrose;   Formula=C18H32O16;   Gossypose;   InChI=1S/C18H32O16/c19-1-5-8(22)11(25)13(27)16(31-5)30-3-7-9(23)12(26)14(28)17(32-7)34-18(4-21)15(29)10(24)6(2-20)33-18/h5-17,19-29H,1-4H2/t5-,6-,7-,8+,9-,10-,11+,12+,13-,14-,15+,16+,17-,18+/m1/s1;   InChIKey=MUPFEKGTMRGPLJ-ZQSKZDJDSA-N;   Melitose;   Melitriose;   SMILES=OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@]3(CO)O[C@H](CO)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O;   alpha-D-Galp-(1->6)-alpha-D-Glcp-(1<->2)-beta-D-Fruf;   alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranosyl beta-D-fructofuranoside;   rafinose;   raflinose
 alt_id: CHEBI:15015;   CHEBI:26521;   CHEBI:49843;   CHEBI:8771
 xref: CAS:512-69-6;   HMDB:HMDB0003213;   KEGG:C00492;   KEGG:G00249;   KNApSAcK:C00001145
 xref_mesh: MESH:D011887
 xref: MetaCyc:CPD-1099;   PDBeChem:RAF;   PMID:23317449;   PMID:23879777;   PMID:23882273;   PMID:24001862;   PMID:24354450;   PMID:24360500;   Reaxys:99543;   Wikipedia:Raffinose


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raffinose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Raffinose results in decreased expression of ACACA mRNA CTD PMID:29458019 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Raffinose results in increased expression of ACOX1 mRNA CTD PMID:29458019 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases secretion ISO Raffinose results in increased secretion of ADIPOQ protein CTD PMID:29458019 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO
EXP
Raffinose results in increased phosphorylation of AKT1 protein CTD PMID:29458019 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Raffinose results in decreased expression of FASN mRNA CTD PMID:29458019 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO
EXP
Raffinose results in increased phosphorylation of GSK3B protein CTD PMID:29458019 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Insr insulin receptor increases phosphorylation EXP
ISO
Raffinose results in increased phosphorylation of INSR protein CTD PMID:29458019 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO Raffinose results in increased expression of PPARA mRNA CTD PMID:29458019 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP
ISO
Raffinose results in increased expression of SLC2A4 protein CTD PMID:29458019 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Raffinose results in decreased expression of SREBF1 mRNA CTD PMID:29458019 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              plant metabolite 17360
                raffinose 10
                  1(F)-alpha-D-galactosylraffinose 0
                  stachyose + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            heteroorganic entity 19148
                              organochalcogen compound 18856
                                organooxygen compound 18778
                                  carbohydrates and carbohydrate derivatives 12180
                                    carbohydrate 12180
                                      oligosaccharide 515
                                        trisaccharide 146
                                          raffinose 10
                                            1(F)-alpha-D-galactosylraffinose 0
                                            stachyose + 0
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