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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pregnenolone
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Accession:CHEBI:16581 term browser browse the term
Definition:A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.
Synonyms:related_synonym: (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE;   3beta-Hydroxypregn-5-en-20-one;   5-Pregnen-3beta-ol-20-one;   Formula=C21H32O2;   InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19,23H,5-12H2,1-3H3/t15-,16-,17+,18-,19-,20-,21+/m0/s1;   InChIKey=ORNBQBCIOKFOEO-QGVNFLHTSA-N;   SMILES=[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O
 alt_id: CHEBI:14881;   CHEBI:26241;   CHEBI:45027;   CHEBI:8388;   CHEBI:86573
 xref: Beilstein:2059026;   CAS:145-13-1;   DrugBank:DB02789;   HMDB:HMDB0000253;   KEGG:C01953;   KEGG:D00143;   LINCS:LSM-5550;   LIPID_MAPS_instance:LMST02030088
 xref_mesh: MESH:D011284
 xref: PDBeChem:PLO;   PMID:23572091;   PMID:24385629;   Reaxys:2059026;   Wikipedia:Pregnenolone


show annotations for term's descendants           Sort by:
pregnenolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor decreases activity ISO Pregnenolone results in decreased activity of AHR protein CTD PMID:30203046 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G App amyloid beta precursor protein decreases response to substance EXP Pregnenolone results in decreased susceptibility to APP protein modified form CTD PMID:18926803 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions EXP Pregnenolone inhibits the reaction [Acetylcholine binds to CHRM1 protein]; Pregnenolone inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM1 protein] CTD PMID:15900516 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions EXP Pregnenolone inhibits the reaction [Acetylcholine binds to CHRM3 protein]; Pregnenolone inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM3 protein] CTD PMID:15900516 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases activity ISO Pregnenolone results in decreased activity of CNR1 protein CTD PMID:28220044 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases chemical synthesis
multiple interactions		 ISO
EXP		 CYP11A1 protein results in increased chemical synthesis of Pregnenolone
[Diethylstilbestrol results in decreased expression of CYP11A1 protein] which results in decreased chemical synthesis of Pregnenolone		 CTD PMID:16054388 PMID:19900470 PMID:23873838 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects metabolic processing
increases hydroxylation
multiple interactions		 ISO
EXP		 CYP17A1 protein affects the metabolism of Pregnenolone
CYP17A1 protein mutant form results in increased hydroxylation of Pregnenolone; CYP17A1 protein results in increased hydroxylation of Pregnenolone
[[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; [abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone; [CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]
Plant Extracts inhibits the reaction [Pregnenolone binds to CYP17A1 protein]		 CTD PMID:15562394 PMID:15666820 PMID:15844475 PMID:16030167 PMID:16054388 More... NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Pregnenolone results in increased expression of CYP3A4 mRNA; Pregnenolone results in increased expression of CYP3A4 protein CTD PMID:15650019 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases activity EXP Pregnenolone results in decreased activity of CYP7A1 protein CTD PMID:1175606 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO ESR1 protein affects the reaction [Pregnenolone results in increased expression of GREB1 mRNA] CTD PMID:33405908 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions ISO FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO [FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone; FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression		 ISO ESR1 protein affects the reaction [Pregnenolone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of GREB1 mRNA] CTD PMID:33405908 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Pregnenolone results in increased expression of GSTA2 mRNA CTD PMID:11502894 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO Pregnenolone inhibits the reaction [25-hydroxycholesterol results in decreased activity of HMGCR protein]; Pregnenolone inhibits the reaction [27-hydroxycholesterol results in decreased activity of HMGCR protein] CTD PMID:9059514 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 increases expression ISO Pregnenolone results in increased expression of HSD17B1 mRNA CTD PMID:20956811 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects metabolic processing ISO HSD3B1 protein affects the metabolism of Pregnenolone CTD PMID:16054388 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone; FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases abundance		 EXP 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; benoxaprofen inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; Masoprocol inhibits the reaction [LHB protein results in increased abundance of Pregnenolone] CTD PMID:6430271 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Mybl1 MYB proto-oncogene like 1 multiple interactions
increases expression		 ISO Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of MYBL1 mRNA] CTD PMID:33405908 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO Pregnenolone results in increased activity of NFE2L2 protein CTD PMID:30203046 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO Pregnenolone binds to and results in increased activity of NR1I2 protein
Pregnenolone results in increased activity of NR1I2 protein		 CTD PMID:15650019 PMID:16054614 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Pregnenolone results in increased activity of NR1I3 protein CTD PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression
multiple interactions		 ISO Pregnenolone results in increased expression of SGK1 mRNA
Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of SGK1 mRNA]		 CTD PMID:33405908 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 increases abundance ISO SIGMAR1 protein results in increased abundance of Pregnenolone CTD PMID:22923735 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017 		JBrowse link
17alpha-hydroxypregnenolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects chemical synthesis
increases metabolic processing
multiple interactions
decreases acetylation
affects metabolic processing		 ISO CYP17A1 protein affects the chemical synthesis of 17-alpha-Hydroxypregnenolone
CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone
[[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; [CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]
CYP17A1 protein results in decreased acetylation of 17-alpha-Hydroxypregnenolone
CYP17A1 protein affects the metabolism of 17-alpha-Hydroxypregnenolone		 CTD PMID:15562394 PMID:16030167 PMID:17194026 PMID:29100959 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
pregnenolone 16alpha-carbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression
multiple interactions
decreases expression		 ISO Pregnenolone Carbonitrile results in increased expression of AACS mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of AACS mRNA]
Pregnenolone Carbonitrile results in decreased expression of AACS mRNA		 CTD PMID:22698814 PMID:28903501 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954 		JBrowse link
G Aadac arylacetamide deacetylase decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of AADAC mRNA
NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in decreased expression of AADAC mRNA]		 CTD PMID:22429928 PMID:28903501 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734 		JBrowse link
G Aadat aminoadipate aminotransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AADAT mRNA CTD PMID:19162173 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Aass aminoadipate-semialdehyde synthase increases expression ISO Pregnenolone Carbonitrile results in increased expression of AASS mRNA CTD PMID:28903501 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ABAT mRNA CTD PMID:19162173 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ABCA1 mRNA; Pregnenolone Carbonitrile results in decreased expression of ABCA1 protein CTD PMID:15883047 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
increases expression		 ISO Endotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB11 mRNA] CTD PMID:15456840 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression		 ISO
EXP		 Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]; NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]; NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]
Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA; Pregnenolone Carbonitrile results in increased expression of ABCB1 protein; Pregnenolone Carbonitrile results in increased expression of ABCB1A mRNA		 CTD PMID:15456840 PMID:16819505 PMID:19162173 PMID:29863087 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABCB1B mRNA CTD PMID:29863087 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
decreases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of ABCB4 mRNA
Pregnenolone Carbonitrile results in decreased expression of ABCB4 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 multiple interactions ISO ABCB6 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA] CTD PMID:25623066 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ABCC1 mRNA CTD PMID:11752103 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression		 ISO
EXP		 [Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of ABCC2 mRNA; Endotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA]
Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA; Pregnenolone Carbonitrile results in increased expression of ABCC2 protein		 CTD PMID:15456840 PMID:15917434 PMID:19118567 PMID:19162173 PMID:20888898 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
increases activity		 ISO
EXP		 [Pregnenolone Carbonitrile binds to NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]] which results in increased expression of ABCC3 mRNA; [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC3 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]
Pregnenolone Carbonitrile results in increased activity of ABCC3 protein
Pregnenolone Carbonitrile results in increased expression of ABCC3 mRNA; Pregnenolone Carbonitrile results in increased expression of ABCC3 protein		 CTD PMID:14570758 PMID:15456840 PMID:15833929 PMID:15986414 PMID:19162173 More... NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects expression ISO Pregnenolone Carbonitrile affects the expression of ABCC4 mRNA CTD PMID:31388680 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABCD4 mRNA CTD PMID:28903501 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of ABCG5 mRNA
[Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of ABCG5 mRNA		 CTD PMID:15683829 PMID:20359477 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ABCG8 mRNA CTD PMID:15683829 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Abhd14b abhydrolase domain containing 14b decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ABHD14B mRNA CTD PMID:28903501 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119 		JBrowse link
G Abhd17b abhydrolase domain containing 17B, depalmitoylase increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABHD17B mRNA CTD PMID:22698814 NCBI chr 1:219,198,294...219,232,733
Ensembl chr 1:219,198,471...219,231,933 		JBrowse link
G Ablim1 actin-binding LIM protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABLIM1 mRNA CTD PMID:28903501 NCBI chr 1:256,084,293...256,372,075
Ensembl chr 1:256,084,297...256,371,969 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABLIM3 mRNA CTD PMID:28903501 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380 		JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression
decreases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of ABTB2 mRNA
Pregnenolone Carbonitrile results in decreased expression of ABTB2 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACAA1B mRNA CTD PMID:28903501 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ACAA2 mRNA CTD PMID:19162173 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of ACACA mRNA] CTD PMID:20359477 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACAT1 mRNA CTD PMID:19162173 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of ACAT2 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acbd4 acyl-CoA binding domain containing 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACBD4 mRNA CTD PMID:28903501 NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500 		JBrowse link
G Acbd5 acyl-CoA binding domain containing 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACBD5 mRNA CTD PMID:28903501 NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215 		JBrowse link
G Acer2 alkaline ceramidase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACER2 mRNA CTD PMID:28903501 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acly ATP citrate lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACLY mRNA CTD PMID:19162173 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Aco2 aconitase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACO2 mRNA CTD PMID:28903501 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acod1 aconitate decarboxylase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACOD1 mRNA CTD PMID:22698814 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACOT1 mRNA CTD PMID:19162173 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACOT2 mRNA CTD PMID:19162173 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACOT3 mRNA CTD PMID:27413110 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACOT4 mRNA CTD PMID:28903501 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acot6 acyl-CoA thioesterase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACOT6 mRNA CTD PMID:22698814 NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACOX1 mRNA CTD PMID:28903501 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACOX2 mRNA CTD PMID:19162173 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of ACSL1 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of ACSL1 mRNA]		 CTD PMID:19162173 PMID:20359477 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSL4 mRNA CTD PMID:28903501 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSL5 mRNA CTD PMID:28903501 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of ACSM2A mRNA
Pregnenolone Carbonitrile results in increased expression of ACSM2 mRNA		 CTD PMID:19162173 PMID:22698814 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACSM3 mRNA CTD PMID:19162173 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Acsm5 acyl-CoA synthetase medium-chain family member 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSM5 mRNA CTD PMID:28903501 NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSS2 mRNA CTD PMID:28903501 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACTA2 mRNA CTD PMID:28903501 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actg1 actin, gamma 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ACTG1 mRNA CTD PMID:19162173 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 		JBrowse link
G Acy3 aminoacylase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACY3 mRNA CTD PMID:28903501 NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175 		JBrowse link
G Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADAMTS14 mRNA CTD PMID:28903501 NCBI chr20:29,143,029...29,219,846
Ensembl chr20:29,144,354...29,219,866 		JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADAMTS15 mRNA CTD PMID:28903501 NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249 		JBrowse link
G Adamtsl2 ADAMTS-like 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADAMTSL2 mRNA CTD PMID:28903501 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADARB1 mRNA CTD PMID:28903501 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adck5 aarF domain containing kinase 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADCK5 mRNA CTD PMID:28903501 NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436 		JBrowse link
G Adcy1 adenylate cyclase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADCY1 mRNA CTD PMID:28903501 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969 		JBrowse link
G Add1 adducin 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ADD1 mRNA CTD PMID:19162173 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of ADH1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADH4 mRNA CTD PMID:28903501 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADH7 mRNA CTD PMID:28903501 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADHFE1 mRNA CTD PMID:27413110 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517 		JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADRB3 mRNA CTD PMID:28903501 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO Pregnenolone Carbonitrile results in increased expression of AEN mRNA CTD PMID:28903501 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Afm afamin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AFM mRNA CTD PMID:28903501 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870 		JBrowse link
G Afp alpha-fetoprotein decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of AFP mRNA
[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of AFP mRNA		 CTD PMID:27413110 PMID:28903501 PMID:33398415 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AGER mRNA CTD PMID:19162173 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Ago1 argonaute RISC component 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of AGO1 mRNA CTD PMID:22698814 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546 		JBrowse link
G Agxt alanine--glyoxylate aminotransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AGXT mRNA CTD PMID:19162173 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Ahcy adenosylhomocysteinase increases expression ISO Pregnenolone Carbonitrile results in increased expression of AHCY mRNA CTD PMID:28903501 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]] CTD PMID:28428138 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AIF1 mRNA CTD PMID:19162173 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AIFM2 mRNA CTD PMID:19162173 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236 		JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AIFM3 mRNA CTD PMID:28903501 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248 		JBrowse link
G Akap17a A-kinase anchoring protein 17A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AKAP17B mRNA CTD PMID:28903501 NCBI chr12:16,310,427...16,315,166
Ensembl chr12:16,310,437...16,314,479 		JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in increased expression of AKR1B7 mRNA
NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of AKR1B7 mRNA]		 CTD PMID:25949234 PMID:27413110 PMID:28903501 NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AKR1C6 mRNA CTD PMID:28903501 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of AKR1D1 mRNA CTD PMID:28903501 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of AKR7A3 mRNA CTD PMID:19162173 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of ALAS1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of ALDH1A1 mRNA
[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ALDH1A1 intron]] which results in increased expression of ALDH1A1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ALDH1A1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ALDH1A1 intron]		 CTD PMID:17998271 PMID:19162173 PMID:20693526 PMID:22496397 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDH1B1 mRNA CTD PMID:17998271 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression
decreases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of ALDH1L1 mRNA
Pregnenolone Carbonitrile results in decreased expression of ALDH1L1 mRNA		 CTD PMID:19162173 PMID:27413110 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ALDH3A2 mRNA CTD PMID:28903501 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDH4A1 mRNA CTD PMID:28903501 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ALDH6A1 mRNA CTD PMID:27413110 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDH8A1 mRNA CTD PMID:17998271 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDOB mRNA CTD PMID:22698814 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Alkbh1 alkB homolog 1, histone H2A dioxygenase increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALKBH1 mRNA CTD PMID:28903501 NCBI chr 6:107,068,309...107,088,779
Ensembl chr 6:107,068,475...107,088,759 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ALOX5 mRNA CTD PMID:22698814 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AMACR mRNA CTD PMID:19162173 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO Pregnenolone Carbonitrile results in increased expression of AMBP mRNA CTD PMID:28903501 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog increases expression ISO Pregnenolone Carbonitrile results in increased expression of AMN1 mRNA CTD PMID:28903501 NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016 		JBrowse link
G Amph amphiphysin increases expression EXP Pregnenolone Carbonitrile results in increased expression of AMPH mRNA CTD PMID:19162173 NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315 		JBrowse link
G Amt aminomethyltransferase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AMT mRNA CTD PMID:28903501 NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ANGPTL4 mRNA CTD PMID:28903501 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ANKIB1 mRNA CTD PMID:28903501 NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781 		JBrowse link
G Ankle1 ankyrin repeat and LEM domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ANKLE1 mRNA CTD PMID:22698814 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ANKRD24 mRNA CTD PMID:19162173 NCBI chr 7:8,061,634...8,081,142
Ensembl chr 7:8,061,953...8,081,142 		JBrowse link
G Anks4b ankyrin repeat and sterile alpha motif domain containing 4B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ANKS4B mRNA CTD PMID:28903501 NCBI chr 1:174,534,195...174,557,798
Ensembl chr 1:174,547,473...174,557,797 		JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ANPEP mRNA CTD PMID:19162173 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Anxa2 annexin A2 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA2 mRNA] CTD PMID:20359477 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa3 annexin A3 decreases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of ANXA3 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA3 mRNA]		 CTD PMID:19162173 PMID:20359477 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa4 annexin A4 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA4 mRNA] CTD PMID:20359477 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Anxa5 annexin A5 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA5 mRNA] CTD PMID:20359477 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of AP3M1 mRNA CTD PMID:19162173 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844 		JBrowse link
G Apba3 amyloid beta precursor protein binding family A member 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of APBA3 mRNA CTD PMID:19162173 NCBI chr 7:8,446,212...8,451,310
Ensembl chr 7:8,446,216...8,451,241 		JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of APBB3 mRNA CTD PMID:28903501 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094 		JBrowse link
G Apcs amyloid P component, serum increases expression ISO Pregnenolone Carbonitrile results in increased expression of APCS mRNA CTD PMID:28903501 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of APEX1 mRNA
Pregnenolone Carbonitrile results in increased expression of APEX1 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aplp2 amyloid beta precursor like protein 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APLP2 mRNA CTD PMID:19162173 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855 		JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of APOA1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APOBEC1 mRNA CTD PMID:19162173 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APOC3 mRNA CTD PMID:19162173 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Apoc4 apolipoprotein C4 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APOC4 mRNA CTD PMID:19162173 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981 		JBrowse link
G Apol9a apolipoprotein L 9a decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of APOL9A mRNA CTD PMID:28903501 NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649 		JBrowse link
G App amyloid beta precursor protein increases expression EXP Pregnenolone Carbonitrile results in increased expression of APP mRNA CTD PMID:19162173 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AQP4 mRNA CTD PMID:28903501 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp7 aquaporin 7 increases expression EXP Pregnenolone Carbonitrile results in increased expression of AQP7 mRNA CTD PMID:19162173 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AQP8 mRNA CTD PMID:28903501 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Aqp9 aquaporin 9 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AQP9 mRNA CTD PMID:19162173 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Ar androgen receptor increases expression EXP Pregnenolone Carbonitrile results in increased expression of AR mRNA CTD PMID:19162173 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARHGAP29 mRNA CTD PMID:28903501 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028 		JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARHGEF16 mRNA CTD PMID:28903501 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212 		JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARHGEF19 mRNA CTD PMID:28903501 NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARHGEF26 mRNA CTD PMID:28903501 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARHGEF3 mRNA CTD PMID:28903501 NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945 		JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARID5A mRNA CTD PMID:28903501 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARL4A mRNA CTD PMID:28903501 NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066 		JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A increases expression EXP Pregnenolone Carbonitrile results in increased expression of ARL5A mRNA CTD PMID:19162173 NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211 		JBrowse link
G Arrb1 arrestin, beta 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARRB1 mRNA CTD PMID:28903501 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARRDC3 mRNA CTD PMID:28903501 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978 		JBrowse link
G Arsa arylsulfatase A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARSA mRNA CTD PMID:28903501 NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783 		JBrowse link
G Asb13 ankyrin repeat and SOCS box-containing 13 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ASB13 mRNA CTD PMID:28903501 NCBI chr17:66,564,653...66,583,365
Ensembl chr17:66,562,434...66,583,337 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO Pregnenolone Carbonitrile results in increased expression of ASF1B mRNA CTD PMID:22698814 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Asl argininosuccinate lyase increases expression ISO Pregnenolone Carbonitrile results in increased expression of ASL mRNA CTD PMID:28903501 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Pregnenolone Carbonitrile results in increased expression of ASNS mRNA CTD PMID:27413110 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ASPRV1 mRNA CTD PMID:22698814 NCBI chr 4:119,076,169...119,078,887
Ensembl chr 4:119,077,356...119,078,379 		JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ASS1 mRNA CTD PMID:19162173 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATAD1 mRNA CTD PMID:28903501 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATAD3A mRNA CTD PMID:28903501 NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Atat1 alpha tubulin acetyltransferase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ATAT1 mRNA CTD PMID:28903501 NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
decreases expression		 ISO NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of ATF3 mRNA] CTD PMID:22698814 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atg14 autophagy related 14 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATG14 mRNA CTD PMID:28903501 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113 		JBrowse link
G Atl2 atlastin GTPase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATL2 mRNA CTD PMID:28903501 NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421 		JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP10D mRNA CTD PMID:28903501 NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ATP1B1 mRNA CTD PMID:19162173 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP4A mRNA CTD PMID:22698814 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ATPIF1 mRNA CTD PMID:19162173 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP5K mRNA CTD PMID:28903501 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP6V0A4 mRNA CTD PMID:28903501 NCBI chr 4:66,760,159...66,842,110
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP Pregnenolone Carbonitrile results in increased expression of ATP6V1D mRNA CTD PMID:19162173 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Atrn attractin decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ATRN mRNA CTD PMID:19162173 NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322 		JBrowse link
G Atxn7l1 ataxin 7-like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ATXN7L1 mRNA CTD PMID:28903501 NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AVPR1A mRNA CTD PMID:19162173 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Axin2 axin 2 multiple interactions ISO [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of AXIN2 mRNA CTD PMID:33398415 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G B3galt1 Beta-1,3-galactosyltransferase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of B3GALT1 mRNA CTD PMID:28903501 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313 		JBrowse link
G B3gntl1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of B3GNTL1 mRNA CTD PMID:19162173 NCBI chr10:106,870,237...106,933,723
Ensembl chr10:106,873,169...106,933,637 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of B4GALT1 mRNA CTD PMID:28903501 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression ISO Pregnenolone Carbonitrile results in increased expression of BAAT mRNA CTD PMID:27413110 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of BAD mRNA CTD PMID:19162173 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BAIAP2 mRNA CTD PMID:28903501 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of BAK1 protein CTD PMID:19433268 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of BAX protein CTD PMID:19433268 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCAT2 mRNA CTD PMID:28903501 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007 		JBrowse link
G Bche butyrylcholinesterase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCHE mRNA CTD PMID:28903501 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Pregnenolone Carbonitrile results in increased expression of BCL2 mRNA CTD PMID:19162173 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCL2A1B mRNA CTD PMID:22698814 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression		 ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of BCL2L1 mRNA]
Pregnenolone Carbonitrile results in increased expression of BCL2L1 mRNA		 CTD PMID:19433268 PMID:28903501 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bco2 beta-carotene oxygenase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCO2 mRNA CTD PMID:28903501 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467 		JBrowse link
G Bcor BCL6 co-repressor increases expression ISO Pregnenolone Carbonitrile results in increased expression of BCOR mRNA CTD PMID:28903501 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BDH1 mRNA CTD PMID:28903501 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase increases expression ISO Pregnenolone Carbonitrile results in increased expression of BHMT mRNA CTD PMID:28903501 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bin1 bridging integrator 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of BIN1 mRNA CTD PMID:19162173 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in increased expression of BIRC5 mRNA
[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNA		 CTD PMID:22698814 PMID:28903501 PMID:33398415 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bivm basic, immunoglobulin-like variable motif containing decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BIVM mRNA CTD PMID:28903501 NCBI chr 9:46,268,758...46,305,038
Ensembl chr 9:46,269,252...46,305,024 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARNTL mRNA CTD PMID:27413110 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmper BMP-binding endothelial regulator increases expression ISO Pregnenolone Carbonitrile results in increased expression of BMPER mRNA CTD PMID:28903501 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BNIP3 mRNA CTD PMID:28903501 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP Pregnenolone Carbonitrile results in increased expression of BNIP3L mRNA CTD PMID:19162173 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of BRCA1 mRNA CTD PMID:23626729 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of BRCA2 mRNA CTD PMID:23626729 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of BRCC3 mRNA CTD PMID:19162173 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Brix1 biogenesis of ribosomes BRX1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BRIX1 mRNA CTD PMID:28903501 NCBI chr 2:59,450,608...59,461,486
Ensembl chr 2:59,450,614...59,461,495 		JBrowse link
G Btf3 basic transcription factor 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BTF3 mRNA CTD PMID:28903501 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879 		JBrowse link
G C1qb complement C1q B chain decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of C1QB mRNA CTD PMID:19162173 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1r complement C1r decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of C1R mRNA CTD PMID:19162173 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C3 complement C3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of C3 mRNA CTD PMID:28903501 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4a complement C4A increases expression ISO Pregnenolone Carbonitrile results in increased expression of C4A mRNA CTD PMID:28903501 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D increases expression ISO Pregnenolone Carbonitrile results in increased expression of CACNA1D mRNA CTD PMID:22698814 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CACNB4 mRNA CTD PMID:28903501 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CAMK2N1 mRNA CTD PMID:19162173 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CAMKK2 mRNA CTD PMID:19162173 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CAMSAP2 mRNA CTD PMID:22698814 NCBI chr13:47,723,121...47,802,597
Ensembl chr13:47,723,121...47,802,597 		JBrowse link
G Car14 carbonic anhydrase 14 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CAR14 mRNA CTD PMID:28903501 NCBI chr 2:183,442,263...183,449,207
Ensembl chr 2:183,441,667...183,449,693 		JBrowse link
G Car3 carbonic anhydrase 3 decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CAR3 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Car9 carbonic anhydrase 9 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CAR9 mRNA CTD PMID:22698814 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp1 caspase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CASP1 mRNA CTD PMID:19162173 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CASP3 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased cleavage of CASP3 protein]		 CTD PMID:19162173 PMID:19433268 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CASP6 mRNA CTD PMID:19162173 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cavin3 caveolae associated protein 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CAVIN3 mRNA CTD PMID:19162173 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161 		JBrowse link
G Cbx2 chromobox 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CBX2 mRNA CTD PMID:28903501 NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383 		JBrowse link
G Cbx4 chromobox 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CBX4 mRNA CTD PMID:28903501 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706 		JBrowse link
G Cbx5 chromobox 5 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CBX5 mRNA CTD PMID:19162173 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Cbx8 chromobox 8 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CBX8 mRNA CTD PMID:28903501 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024 		JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CC2D2A mRNA CTD PMID:28903501 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949 		JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCDC86 mRNA CTD PMID:28903501 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of CCL2 mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of CCL2 mRNA]		 CTD PMID:22698814 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCL6 mRNA CTD PMID:28903501 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of CCN1 mRNA
[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of CCN1 mRNA		 CTD PMID:28903501 PMID:33398415 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCN2 mRNA CTD PMID:28903501 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA; [pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA; [Pregnenolone Carbonitrile co-treated with Phenobarbital] results in increased expression of CCNA2 mRNA CTD PMID:23626729 PMID:33398415 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CCNB1 mRNA
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA; [pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA		 CTD PMID:19162173 PMID:23626729 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB2 mRNA CTD PMID:23626729 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CCND1 mRNA CTD PMID:19162173 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnf cyclin F decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CCNF mRNA CTD PMID:28903501 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCT2 mRNA CTD PMID:28903501 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCT3 mRNA CTD PMID:28903501 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cd19 CD19 molecule decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CD19 mRNA CTD PMID:28903501 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975 		JBrowse link
G Cd22 CD22 molecule decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CD22 mRNA CTD PMID:28903501 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322 		JBrowse link
G Cd36 CD36 molecule decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CD36 mRNA CTD PMID:19162173 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd74 CD74 molecule decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CD74 mRNA CTD PMID:19162173 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cd81 Cd81 molecule decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CD81 mRNA CTD PMID:19162173 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cd82 Cd82 molecule increases expression EXP Pregnenolone Carbonitrile results in increased expression of CD82 mRNA CTD PMID:19162173 NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809 		JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CDC14B mRNA CTD PMID:28903501 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235 		JBrowse link
G Cdc20 cell division cycle 20 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CDC20 mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CDC20 mRNA]		 CTD PMID:19162173 PMID:21318169 PMID:22698814 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDC45 mRNA CTD PMID:22698814 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDCA3 mRNA CTD PMID:22698814 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDCA8 mRNA CTD PMID:22698814 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh15 cadherin 15 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDH15 mRNA CTD PMID:28903501 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105 		JBrowse link
G Cdh2 cadherin 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CDH2 mRNA CTD PMID:19162173 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdhr5 cadherin-related family member 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDHR5 mRNA CTD PMID:28903501 NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543 		JBrowse link
G Cdip1 cell death-inducing p53 target 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDIP1 mRNA CTD PMID:28903501 NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in increased expression of CDK1 mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CDK1 mRNA]		 CTD PMID:22698814 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk18 cyclin-dependent kinase 18 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDK18 mRNA CTD PMID:28903501 NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDKN1A mRNA CTD PMID:28903501 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDKN3 mRNA CTD PMID:22698814 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CDO1 mRNA CTD PMID:19162173 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CEBPA mRNA CTD PMID:28903501 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CEBPB mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Pregnenolone Carbonitrile results in increased expression of CEBPD mRNA CTD PMID:28903501 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Cebpzos CEBPZ opposite strand increases expression ISO Pregnenolone Carbonitrile results in increased expression of CEBPZOS mRNA CTD PMID:28903501 NCBI chr 6:16,135,546...16,140,254
Ensembl chr 6:16,133,410...16,140,151 		JBrowse link
G Celf1 CUGBP, Elav-like family member 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CELF1 mRNA CTD PMID:19162173 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426 		JBrowse link
G Cenpe centromere protein E increases expression ISO Pregnenolone Carbonitrile results in increased expression of CENPE mRNA CTD PMID:22698814 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cenph centromere protein H increases expression ISO Pregnenolone Carbonitrile results in increased expression of CENPH mRNA CTD PMID:22698814 NCBI chr 2:31,894,253...31,910,182
Ensembl chr 2:31,894,667...31,910,154 		JBrowse link
G Cenpp centromere protein P increases expression ISO Pregnenolone Carbonitrile results in increased expression of CENPP mRNA CTD PMID:22698814 NCBI chr17:15,013,869...15,189,312
Ensembl chr17:15,014,058...15,189,304 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression		 ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CES1D mRNA]
Pregnenolone Carbonitrile results in increased expression of CES1D mRNA; Pregnenolone Carbonitrile results in increased expression of CES1D protein		 CTD PMID:20359477 PMID:26179144 PMID:28903501 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2c carboxylesterase 2C multiple interactions
increases expression		 ISO NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CES2C mRNA] CTD PMID:22429928 PMID:26179144 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Ces2e carboxylesterase 2E increases expression
decreases expression		 ISO Pregnenolone Carbonitrile results in increased expression of CES2E mRNA
Pregnenolone Carbonitrile results in decreased expression of CES2E mRNA		 CTD PMID:26179144 PMID:28903501 NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856 		JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Pregnenolone Carbonitrile results in increased expression of CES2 mRNA CTD PMID:19162173 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CES3B mRNA CTD PMID:28903501 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cgn cingulin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CGN mRNA CTD PMID:28903501 NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645 		JBrowse link
G Ch25h cholesterol 25-hydroxylase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CH25H mRNA CTD PMID:22698814 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CHAC2 mRNA CTD PMID:28903501 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A increases expression
decreases expression		 ISO Pregnenolone Carbonitrile results in increased expression of CHAF1A mRNA
Pregnenolone Carbonitrile results in decreased expression of CHAF1A mRNA		 CTD PMID:22698814 PMID:28903501 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654 		JBrowse link
G Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHCHD4 mRNA CTD PMID:28903501 NCBI chr 4:123,968,264...123,977,398
Ensembl chr 4:123,968,265...123,977,414 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHCHD6 mRNA CTD PMID:19162173 NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHD1L mRNA CTD PMID:28903501 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CHEK1 mRNA CTD PMID:23626729 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chka choline kinase alpha decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CHKA mRNA CTD PMID:28903501 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHORDC1 mRNA CTD PMID:19162173 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Chpt1 choline phosphotransferase 1 multiple interactions ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of CHPT1 mRNA CTD PMID:20359477 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHRM1 mRNA CTD PMID:19162173 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHRM3 mRNA CTD PMID:19162173 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chst15 carbohydrate sulfotransferase 15 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHST15 mRNA CTD PMID:28903501 NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707 		JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHTF18 mRNA CTD PMID:22698814 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050 		JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CIAO1 mRNA CTD PMID:19162173 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP Pregnenolone Carbonitrile results in increased expression of CIDEA mRNA CTD PMID:19162173 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CIITA mRNA CTD PMID:22698814 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CITED2 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ckb creatine kinase B decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CKB mRNA CTD PMID:19162173 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CKS1B mRNA CTD PMID:23626729 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CKS2 mRNA CTD PMID:28903501 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn14 claudin 14 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CLDN14 mRNA CTD PMID:28903501 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171 		JBrowse link
G Cldn3 claudin 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CLDN3 mRNA CTD PMID:19162173 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Clec4d C-type lectin domain family 4, member D decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CLEC4D mRNA CTD PMID:22698814 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848 		JBrowse link
G Clec9a C-type lectin domain containing 9A increases expression ISO Pregnenolone Carbonitrile results in increased expression of CLEC9A mRNA CTD PMID:28903501 NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352 		JBrowse link
G Clic3 chloride intracellular channel 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CLIC3 mRNA CTD PMID:28903501 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018 		JBrowse link
G Clstn3 calsyntenin 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CLSTN3 mRNA CTD PMID:28903501 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769 		JBrowse link
G Cltb clathrin, light chain B increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CLTB mRNA CTD PMID:19162173 PMID:28903501 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169 		JBrowse link
G Clu clusterin increases expression ISO Pregnenolone Carbonitrile results in increased expression of CLU mRNA CTD PMID:28903501 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CNRIP1 mRNA CTD PMID:22698814 NCBI chr14:91,463,046...91,492,736
Ensembl chr14:91,462,647...91,492,735 		JBrowse link
G Cntn5 contactin 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CNTN5 mRNA CTD PMID:22698814 NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of COL15A1 mRNA CTD PMID:28903501 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Colgalt2 collagen beta(1-O)galactosyltransferase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of COLGALT2 mRNA CTD PMID:22698814 PMID:28903501 NCBI chr13:64,523,641...64,628,295
Ensembl chr13:64,523,658...64,627,549 		JBrowse link
G Comt catechol-O-methyltransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of COMT mRNA CTD PMID:19162173 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Coro2a coronin 2A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CORO2A mRNA CTD PMID:28903501 NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of COX5A mRNA CTD PMID:19162173 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox8a cytochrome c oxidase subunit 8A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of COX8A mRNA CTD PMID:19162173 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cpb2 carboxypeptidase B2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CPB2 mRNA CTD PMID:28903501 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CPEB2 mRNA CTD PMID:22698814 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743 		JBrowse link
G Cpne8 copine 8 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CPNE8 mRNA CTD PMID:28903501 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CPS1 mRNA CTD PMID:19162173 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CPT1B mRNA CTD PMID:19162173 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpxm2 carboxypeptidase X (M14 family), member 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CPXM2 mRNA CTD PMID:22698814 NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220 		JBrowse link
G Crcp CGRP receptor component increases expression ISO Pregnenolone Carbonitrile results in increased expression of CRCP mRNA CTD PMID:28903501 NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CREG1 mRNA CTD PMID:19162173 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308 		JBrowse link
G Crip2 cysteine-rich protein 2 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CRIP2 mRNA
Pregnenolone Carbonitrile results in increased expression of CRIP2 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CROT mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CROT mRNA]		 CTD PMID:19162173 PMID:20359477 PMID:28903501 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Crp C-reactive protein increases expression ISO Pregnenolone Carbonitrile results in increased expression of CRP mRNA CTD PMID:28903501 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cryaa crystallin, alpha A increases expression EXP Pregnenolone Carbonitrile results in increased expression of CRYAA mRNA CTD PMID:19162173 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349 		JBrowse link
G Crybb1 crystallin, beta B1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CRYBB1 mRNA CTD PMID:22698814 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344 		JBrowse link
G Crybb3 crystallin, beta B3 decreases expression
increases expression		 ISO Pregnenolone Carbonitrile results in decreased expression of CRYBB3 mRNA
Pregnenolone Carbonitrile results in increased expression of CRYBB3 mRNA		 CTD PMID:22698814 PMID:28903501 NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Pregnenolone Carbonitrile results in increased expression of CSF2RB mRNA; Pregnenolone Carbonitrile results in increased expression of CSF2RB2 mRNA CTD PMID:28903501 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CSRNP1 mRNA CTD PMID:28903501 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Cstb cystatin B decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CSTB mRNA CTD PMID:19162173 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CTH mRNA CTD PMID:19162173 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnd2 catenin delta 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CTNND2 mRNA CTD PMID:19162173 NCBI chr 2:81,168,976...82,016,495
Ensembl chr 2:81,167,117...82,015,764 		JBrowse link
G Ctps1 CTP synthase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CTPS mRNA CTD PMID:28903501 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180 		JBrowse link
G Ctsd cathepsin D increases expression EXP Pregnenolone Carbonitrile results in increased expression of CTSD mRNA CTD PMID:19162173 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsl cathepsin L decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CTSL mRNA
Pregnenolone Carbonitrile results in increased expression of CTSL mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Ctss cathepsin S decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CTSS mRNA CTD PMID:19162173 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CUTA mRNA CTD PMID:19162173 NCBI chr20:5,022,956...5,024,580
Ensembl chr20:5,022,956...5,024,552 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CXCL1 mRNA CTD PMID:27413110 PMID:28903501 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyb561 cytochrome b-561 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYB561 mRNA CTD PMID:28903501 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787 		JBrowse link
G Cyb5a cytochrome b5 type A affects expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile affects the expression of CYB5A mRNA
Pregnenolone Carbonitrile results in increased expression of CYB5A mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYB5R3 mRNA CTD PMID:19162173 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298 		JBrowse link
G Cyc1 cytochrome c-1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYC1 mRNA CTD PMID:19162173 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cycs cytochrome c, somatic decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYCS mRNA CTD PMID:19162173 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP17A1 mRNA CTD PMID:19162173 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CYP1A1 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP1A1 mRNA
Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]		 CTD PMID:19118567 PMID:19162173 PMID:28428138 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CYP1A2 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP1A2 mRNA
Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]
NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in decreased expression of CYP1A2 mRNA]		 CTD PMID:15596064 PMID:19162173 PMID:27413110 PMID:28428138 PMID:29548889 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA] CTD PMID:28428138 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP24A1 mRNA CTD PMID:15630458 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP26A1 mRNA CTD PMID:28903501 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP27A1 mRNA CTD PMID:28903501 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2A1 mRNA CTD PMID:15596064 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2A2 mRNA CTD PMID:19162173 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP2A4 mRNA CTD PMID:27413110 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
affects expression		 ISO
EXP		 [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Pregnenolone Carbonitrile co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA; [Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP2B10 gene]] which results in increased expression of CYP2B10 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA]; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA]; NR1I3 protein promotes the reaction [[Pregnenolone Carbonitrile co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP2B10 gene]; Pregnenolone Carbonitrile promotes the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA]
Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP2B10 protein
NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B1 mRNA]
Pregnenolone Carbonitrile affects the expression of CYP2B10 mRNA		 CTD PMID:15986414 PMID:17627975 PMID:18488193 PMID:19433268 PMID:20359477 More... NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2B15 mRNA CTD PMID:19162173 PMID:19850644 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CYP2B2 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP2B13 mRNA
NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B2 mRNA]		 CTD PMID:15596064 PMID:19162173 PMID:19850644 PMID:27413110 PMID:29548889 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CYP2B3 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP2B3 mRNA
Pregnenolone Carbonitrile results in decreased expression of CYP2B9 mRNA		 CTD PMID:15596064 PMID:19162173 PMID:27413110 PMID:28903501 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2C mRNA CTD PMID:19162173 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2C22 mRNA CTD PMID:19162173 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions
increases expression		 ISO NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C55 mRNA]; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C55 mRNA] CTD PMID:20371638 PMID:22698814 PMID:27413110 PMID:28903501 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CYP2C38 mRNA CTD PMID:28903501 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP2C29 mRNA CTD PMID:28903501
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP2D3 mRNA CTD PMID:19162173 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CYP2F4 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP2F1 mRNA
Pregnenolone Carbonitrile results in decreased expression of CYP2F2 mRNA		 CTD PMID:15596064 PMID:19162173 PMID:27413110 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP2J3 mRNA CTD PMID:19162173 NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CYP2U1 mRNA CTD PMID:28903501 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882 		JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP3A18 mRNA CTD PMID:15596064 PMID:19162173 PMID:19850644 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases activity
increases expression		 EXP
ISO		 [NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]; Pregnenolone Carbonitrile results in increased expression of and results in increased activity of CYP3A2 protein
Pregnenolone Carbonitrile results in increased activity of CYP3A2 protein
Pregnenolone Carbonitrile results in increased expression of CYP3A2 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP3A2 protein
Pregnenolone Carbonitrile results in increased expression of CYP3A4 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP3A4 protein
[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 gene promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A4 protein]; NR3C1 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A4 mRNA]		 CTD PMID:10219967 PMID:12458634 PMID:12505310 PMID:15541768 PMID:15588932 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases expression
increases activity		 EXP [Dietary Fats co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A23-3A1 protein; Clofibrate promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 protein]; diphenyleneiodonium inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of CYP3A23-3A1 protein]; NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 mRNA]; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 mRNA]; perfluorodecanoic acid inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 protein]; Pregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]
Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 protein		 CTD PMID:9817075 PMID:10772642 PMID:11752103 PMID:12370413 PMID:12869653 More... NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of CYP3A9 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP3A13 mRNA
trichostatin A inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]		 CTD PMID:15596064 PMID:19162173 PMID:19562681 PMID:19850644 PMID:20888898 More... NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4A1 mRNA CTD PMID:19162173 PMID:29548889 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4A2 mRNA CTD PMID:19162173 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4A3 mRNA CTD PMID:19162173 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4B1 mRNA CTD PMID:15596064 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of CYP4F14 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP4F14 mRNA]		 CTD PMID:20359477 PMID:28903501 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046 		JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP4F4 mRNA CTD PMID:15596064 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506 		JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP4F5 mRNA CTD PMID:19162173 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978 		JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CYP4V3 mRNA CTD PMID:28903501 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP7A1 mRNA]		 CTD PMID:15629111 PMID:19162173 PMID:20359477 PMID:22982774 PMID:27413110 More... NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP7B1 mRNA CTD PMID:19162173 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP8B1 mRNA] CTD PMID:20359477 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DAAM1 mRNA CTD PMID:28903501 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114 		JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DACT2 mRNA CTD PMID:19162173 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096 		JBrowse link
G Dancr differentiation antagonizing non-protein coding RNA increases expression ISO Pregnenolone Carbonitrile results in increased expression of DANCR mRNA CTD PMID:28903501 NCBI chr14:34,126,956...34,127,936 JBrowse link
G Dapk3 death-associated protein kinase 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DAPK3 mRNA CTD PMID:19162173 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Dbndd1 dysbindin domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DBNDD1 mRNA CTD PMID:22698814 NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of DBP mRNA
Pregnenolone Carbonitrile results in increased expression of DBP mRNA		 CTD PMID:19162173 PMID:27413110 PMID:28903501 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DCAF11 mRNA CTD PMID:19162173 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669 		JBrowse link
G Dcdc2 doublecortin domain containing 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DCDC2A mRNA CTD PMID:22698814 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743 		JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DCUN1D4 mRNA CTD PMID:28903501 NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DDAH1 mRNA CTD PMID:28903501 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DDC mRNA CTD PMID:28903501 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DDIT4 mRNA CTD PMID:28903501 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx21 DExD-box helicase 21 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DDX21 mRNA CTD PMID:28903501 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Ddx27 DEAD-box helicase 27 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DDX27 mRNA CTD PMID:28903501 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372 		JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DEPDC7 mRNA CTD PMID:28903501 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124 		JBrowse link
G Derl3 derlin 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DERL3 mRNA CTD PMID:28903501 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027 		JBrowse link
G Desi2 desumoylating isopeptidase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DESI2 mRNA CTD PMID:28903501 NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416 		JBrowse link
G Dexi Dexi homolog decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DEXI mRNA CTD PMID:28903501 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738 		JBrowse link
G Dgkg diacylglycerol kinase, gamma increases expression EXP Pregnenolone Carbonitrile results in increased expression of DGKG mRNA CTD PMID:19162173 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212 		JBrowse link
G Dgkz diacylglycerol kinase zeta decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DGKZ mRNA CTD PMID:19162173 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099 		JBrowse link
G Dhdh dihydrodiol dehydrogenase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DHDH mRNA CTD PMID:28903501 NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197 		JBrowse link
G Dhrs1 dehydrogenase/reductase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DHRS1 mRNA CTD PMID:28903501 NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838 		JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DHX36 mRNA CTD PMID:19162173 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DIO1 mRNA CTD PMID:19162173 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease increases expression ISO Pregnenolone Carbonitrile results in increased expression of DIS3 mRNA CTD PMID:28903501 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642 		JBrowse link
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DIS3L2 mRNA CTD PMID:19162173 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of DLAT mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DLC1 mRNA CTD PMID:28903501 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DLL1 mRNA CTD PMID:28903501 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression ISO Pregnenolone Carbonitrile results in increased expression of DLST mRNA CTD PMID:28903501 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like increases expression EXP Pregnenolone Carbonitrile results in increased expression of DMAC2L mRNA CTD PMID:19162173 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DNAJA3 mRNA CTD PMID:28903501 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DNAJB9 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnm3 dynamin 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DNM3 mRNA CTD PMID:19162173 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108 		JBrowse link
G Dop1a DOP1 leucine zipper like protein A increases expression ISO Pregnenolone Carbonitrile results in increased expression of DOP1A mRNA CTD PMID:28903501 NCBI chr 8:87,415,266...87,517,935
Ensembl chr 8:87,414,593...87,518,353 		JBrowse link
G Dop1b DOP1 leucine zipper like protein B increases expression ISO Pregnenolone Carbonitrile results in increased expression of DOP1B mRNA CTD PMID:28903501 NCBI chr11:33,024,376...33,125,931
Ensembl chr11:33,024,411...33,125,931 		JBrowse link
G Dpp9 dipeptidyl peptidase 9 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DPP9 mRNA CTD PMID:28903501 NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541 		JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DRG1 mRNA CTD PMID:28903501 NCBI chr14:78,103,876...78,119,976
Ensembl chr14:78,103,876...78,119,953 		JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DSC2 mRNA CTD PMID:28903501 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392 		JBrowse link
G Dsg2 desmoglein 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DSG2 mRNA CTD PMID:28903501 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156 		JBrowse link
G Dsp desmoplakin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DSP mRNA CTD PMID:28903501 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DTX4 mRNA CTD PMID:28903501 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DUSP1 mRNA CTD PMID:19162173 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 affects expression EXP Pregnenolone Carbonitrile affects the expression of DUSP6 mRNA CTD PMID:19162173 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dxo decapping exoribonuclease increases expression ISO Pregnenolone Carbonitrile results in increased expression of DXO mRNA CTD PMID:28903501 NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494 		JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DYNC1H1 mRNA CTD PMID:19162173 NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883 		JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DYNC2H1 mRNA CTD PMID:19162173 NCBI chr 8:4,189,257...4,412,183
Ensembl chr 8:4,189,257...4,412,183 		JBrowse link
G Dynll2 dynein light chain LC8-type 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DYNLL2 mRNA CTD PMID:28903501 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of E2F1 mRNA CTD PMID:23626729 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of E2F2 mRNA CTD PMID:28903501 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EBNA1BP2 mRNA CTD PMID:28903501 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ECH1 mRNA CTD PMID:19162173 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ECHDC3 mRNA CTD PMID:28903501 NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ECHS1 mRNA CTD PMID:19162173 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EEF1B2 mRNA CTD PMID:28903501 NCBI chr 9:64,580,009...64,582,737
Ensembl chr 9:64,579,893...64,582,737 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EEF2K mRNA CTD PMID:28903501 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164 		JBrowse link
G Efna3 ephrin A3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EFNA3 mRNA CTD PMID:28903501 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Egfl7 EGF-like-domain, multiple 7 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of EGFL7 mRNA CTD PMID:19162173 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879 		JBrowse link
G Egr1 early growth response 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of EGR1 mRNA CTD PMID:19162173 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EGR2 mRNA CTD PMID:22698814 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of EHHADH mRNA CTD PMID:19162173 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H increases expression ISO Pregnenolone Carbonitrile results in increased expression of EIF3H mRNA CTD PMID:28903501 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EIF4A1 mRNA CTD PMID:28903501 NCBI chr10:54,384,345...54,389,853
Ensembl chr10:54,384,347...54,389,858 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of EIF4A2 mRNA CTD PMID:19162173 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EIF4EBP3 mRNA CTD PMID:28903501 NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Elfn1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ELFN1 mRNA CTD PMID:22698814 NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ELOVL3 mRNA CTD PMID:28903501 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ELOVL5 mRNA CTD PMID:28903501 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ELOVL6 mRNA CTD PMID:28903501 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ELOVL7 mRNA CTD PMID:22698814 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Emb embigin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EMB mRNA CTD PMID:22698814 NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050 		JBrowse link
G Emilin2 elastin microfibril interfacer 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EMILIN2 mRNA CTD PMID:22698814 NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352 		JBrowse link
G Enho energy homeostasis associated decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ENHO mRNA CTD PMID:28903501 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777 		JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ENPP6 mRNA CTD PMID:28903501 NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ENTPD2 mRNA CTD PMID:19162173 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Entrep1 endosomal transmembrane epsin interactor 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ENTREP1 mRNA CTD PMID:22698814 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758 		JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EPAS1 mRNA CTD PMID:28903501 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of EPB41 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821 		JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP Pregnenolone Carbonitrile results in increased expression of EPCAM mRNA CTD PMID:19162173 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Epha1 Eph receptor A1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EPHA1 mRNA CTD PMID:28903501 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA
[Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA		 CTD PMID:19162173 PMID:20359477 PMID:27413110 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EPHX2 mRNA CTD PMID:27413110 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Eppk1 epiplakin 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EPPK1 mRNA CTD PMID:28903501 NCBI chr 7:107,816,919...107,842,946
Ensembl chr 7:107,817,693...107,831,159 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ERN1 mRNA CTD PMID:19162173 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ERO1B mRNA CTD PMID:28903501 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ERP29 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ERRFI1 mRNA CTD PMID:28903501 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Esam endothelial cell adhesion molecule increases expression ISO Pregnenolone Carbonitrile results in increased expression of ESAM mRNA CTD PMID:28903501 NCBI chr 8:37,238,228...37,249,217
Ensembl chr 8:37,238,287...37,249,215 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ESCO2 mRNA CTD PMID:22698814 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Esrra estrogen related receptor, alpha increases expression EXP Pregnenolone Carbonitrile results in increased expression of ESRRA mRNA CTD PMID:19162173 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Etl4 enhancer trap locus 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ETL4 mRNA CTD PMID:28903501 NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715 		JBrowse link
G Etnk2 ethanolamine kinase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ETNK2 mRNA CTD PMID:28903501 NCBI chr13:44,811,224...44,829,037
Ensembl chr13:44,811,015...44,829,037 		JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ETNPPL mRNA CTD PMID:27413110 NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212 		JBrowse link
G Exo1 exonuclease 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXO1 mRNA CTD PMID:22698814 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exosc1 exosome component 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXOSC1 mRNA CTD PMID:28903501 NCBI chr 1:240,734,777...240,745,518
Ensembl chr 1:240,734,773...240,745,438 		JBrowse link
G Exosc2 exosome component 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXOSC2 mRNA CTD PMID:28903501 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575 		JBrowse link
G Exosc8 exosome component 8 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXOSC8 mRNA CTD PMID:28903501 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928 		JBrowse link
G Exph5 exophilin 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EXPH5 mRNA CTD PMID:28903501 NCBI chr 8:53,698,825...53,775,371
Ensembl chr 8:53,698,852...53,773,169 		JBrowse link
G F10 coagulation factor X decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of F10 mRNA CTD PMID:19162173 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G Faah fatty acid amide hydrolase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAAH mRNA CTD PMID:28903501 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FABP1 mRNA CTD PMID:28903501 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of FABP2 mRNA CTD PMID:19162173 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of FABP5 mRNA
Pregnenolone Carbonitrile results in increased expression of FABP5 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FADS2 mRNA CTD PMID:28903501 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fads3 fatty acid desaturase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FADS3 mRNA CTD PMID:28903501 NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769 		JBrowse link
G Fads6 fatty acid desaturase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FADS6 mRNA CTD PMID:20359477 NCBI chr10:100,522,981...100,538,181
Ensembl chr10:100,522,981...100,538,181 		JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAHD1 mRNA CTD PMID:28903501 NCBI chr10:13,873,539...13,874,978
Ensembl chr10:13,873,527...13,875,012 		JBrowse link
G Fam149a family with sequence similarity 149, member A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM149A mRNA CTD PMID:28903501 NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM20C mRNA CTD PMID:28903501 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM78B mRNA CTD PMID:22698814 NCBI chr13:79,162,405...79,250,958
Ensembl chr13:79,162,228...79,250,500 		JBrowse link
G Fanca FA complementation group A increases expression ISO Pregnenolone Carbonitrile results in increased expression of FANCA mRNA CTD PMID:22698814 NCBI chr19:51,304,021...51,362,586
Ensembl chr19:51,304,021...51,362,527 		JBrowse link
G Fancg FA complementation group G increases expression ISO Pregnenolone Carbonitrile results in increased expression of FANCG mRNA CTD PMID:22698814 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Fanci FA complementation group I increases expression ISO Pregnenolone Carbonitrile results in increased expression of FANCI mRNA CTD PMID:22698814 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640 		JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FARP1 mRNA CTD PMID:28903501 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299 		JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of FAS mRNA CTD PMID:19162173 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fasn fatty acid synthase decreases expression
increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of FASN mRNA
Pregnenolone Carbonitrile results in increased expression of FASN mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of FASN mRNA]		 CTD PMID:19162173 PMID:20359477 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbf1 Fas binding factor 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FBF1 mRNA CTD PMID:28903501 NCBI chr10:101,375,769...101,401,624
Ensembl chr10:101,375,775...101,401,644 		JBrowse link
G Fbxo21 F-box protein 21 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FBXO21 mRNA CTD PMID:28903501 NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133 		JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FBXO31 mRNA CTD PMID:28903501 NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010 		JBrowse link
G Fbxo44 F-box protein 44 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FBXO44 mRNA CTD PMID:22698814 NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363 		JBrowse link
G Fcgr2a Fc gamma receptor 2A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of FCGR2A mRNA CTD PMID:19162173 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FDFT1 mRNA CTD PMID:28903501 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FDPS mRNA CTD PMID:28903501 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fdx1 ferredoxin 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FDX1 mRNA CTD PMID:28903501 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fga fibrinogen alpha chain decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of FGA mRNA
Pregnenolone Carbonitrile results in increased expression of FGA mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain increases expression ISO Pregnenolone Carbonitrile results in increased expression of FGB mRNA CTD PMID:28903501 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of FGF1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf21 fibroblast growth factor 21 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FGF21 mRNA CTD PMID:22698814 PMID:28903501 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FGFR4 mRNA CTD PMID:28903501 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FGFRL1 mRNA CTD PMID:28903501 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928 		JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Pregnenolone Carbonitrile results in increased expression of FGG mRNA CTD PMID:28903501 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FGL1 mRNA CTD PMID:28903501 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Fh fumarate hydratase increases expression ISO Pregnenolone Carbonitrile results in increased expression of FH1 mRNA CTD PMID:28903501 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266 		JBrowse link
G Fign fidgetin, microtubule severing factor decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FIGN mRNA CTD PMID:28903501 NCBI chr 3:48,637,510...48,760,772
Ensembl chr 3:48,642,496...48,760,787 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression EXP Pregnenolone Carbonitrile results in increased expression of FKBP11 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303 		JBrowse link
G Fkbp14 FKBP prolyl isomerase 14 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FKBP14 mRNA CTD PMID:28903501 NCBI chr 4:83,705,531...83,721,515
Ensembl chr 4:83,705,652...83,721,528 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 affects expression
increases expression		 EXP Pregnenolone Carbonitrile affects the expression of FKBP4 mRNA
Pregnenolone Carbonitrile results in increased expression of FKBP4 mRNA		 CTD PMID:19162173 PMID:21318169 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FKBP5 mRNA CTD PMID:28903501 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Flcn folliculin increases expression ISO Pregnenolone Carbonitrile results in increased expression of FLCN mRNA CTD PMID:28903501 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Flot2 flotillin 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FLOT2 mRNA CTD PMID:28903501 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of FMO1 mRNA CTD PMID:19162173 PMID:27413110 PMID:28903501 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FMO4 mRNA CTD PMID:28903501 NCBI chr13:75,154,683...75,172,932
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of FN1 mRNA
Pregnenolone Carbonitrile results in increased expression of FN1 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fn3k fructosamine 3 kinase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FN3K mRNA CTD PMID:28903501 NCBI chr10:106,700,302...106,715,903
Ensembl chr10:106,700,670...106,715,895 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of FOS mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of FOS mRNA]		 CTD PMID:22698814 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Pregnenolone Carbonitrile results in increased expression of FOSL2 mRNA CTD PMID:28903501 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxk2 forkhead box K2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of FOXK2 mRNA CTD PMID:19162173 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563 		JBrowse link
G Foxm1 forkhead box M1 increases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in increased expression of FOXM1 mRNA
[Pregnenolone Carbonitrile co-treated with Phenobarbital] results in increased expression of FOXM1 mRNA; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of FOXM1 mRNA]		 CTD PMID:22698814 PMID:33398415 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FOXO1 mRNA CTD PMID:28903501 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Fst follistatin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FST mRNA CTD PMID:28903501 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FTSJ3 mRNA CTD PMID:28903501 NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,180,696...91,187,397 		JBrowse link
G Fuom fucose mutarotase increases expression ISO Pregnenolone Carbonitrile results in increased expression of FUOM mRNA CTD PMID:28903501 NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046 		JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FXYD5 mRNA CTD PMID:22698814 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519 		JBrowse link
G Fzd3 frizzled class receptor 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FZD3 mRNA CTD PMID:22698814 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369 		JBrowse link
G G0s2 G0/G1switch 2 increases expression
decreases expression		 ISO Pregnenolone Carbonitrile results in increased expression of G0S2 mRNA
Pregnenolone Carbonitrile results in decreased expression of G0S2 mRNA		 CTD PMID:27413110 PMID:28903501 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP Pregnenolone Carbonitrile affects the expression of G6PC1 mRNA CTD PMID:19162173 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gaa alpha glucosidase increases expression EXP Pregnenolone Carbonitrile results in increased expression of GAA mRNA CTD PMID:19162173 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of GADD45A mRNA
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of GADD45A mRNA		 CTD PMID:19162173 PMID:23626729 PMID:28903501 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Pregnenolone Carbonitrile results in increased expression of GADD45B mRNA CTD PMID:27413110 PMID:28903501 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Pregnenolone Carbonitrile results in increased expression of GADD45G mRNA CTD PMID:28903501 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GALE mRNA CTD PMID:28903501 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GALNT2 mRNA CTD PMID:28903501 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GAMT mRNA CTD PMID:28903501 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gar1 GAR1 ribonucleoprotein increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAR1 mRNA CTD PMID:28903501 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524 		JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAS2L1 mRNA CTD PMID:22698814 NCBI chr14:79,951,702...79,961,830
Ensembl chr14:79,950,555...79,961,438 		JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAS2L3 mRNA CTD PMID:22698814 NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411 		JBrowse link
G Gas5 growth arrest specific 5 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GAS5 mRNA CTD PMID:19162173 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gas6 growth arrest specific 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GAS6 mRNA CTD PMID:19162173 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAS7 mRNA CTD PMID:22698814 NCBI chr10:52,152,728...52,383,276
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Gbp6 guanylate binding protein family member 6 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GBP6 mRNA CTD PMID:28903501 NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062 		JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GCC2 mRNA CTD PMID:22698814 NCBI chr20:26,247,394...26,293,613
Ensembl chr20:26,247,404...26,293,613 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GCH1 mRNA CTD PMID:19162173 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gck glucokinase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GCK protein CTD PMID:26616219 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
decreases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of GCLC mRNA
Pregnenolone Carbonitrile results in decreased expression of GCLC mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP Pregnenolone Carbonitrile results in increased expression of GCLM mRNA CTD PMID:19162173 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gda guanine deaminase increases expression EXP Pregnenolone Carbonitrile results in increased expression of GDA mRNA CTD PMID:19162173 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GDE1 mRNA CTD PMID:19162173 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GFRA1 mRNA CTD PMID:28903501 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Ggact gamma-glutamylamine cyclotransferase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GGACT mRNA CTD PMID:28903501 NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GGT1 mRNA CTD PMID:19162173 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghr growth hormone receptor decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of GHR mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Ghsr growth hormone secretagogue receptor increases expression EXP Pregnenolone Carbonitrile results in increased expression of GHSR mRNA CTD PMID:19162173 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gin1 gypsy retrotransposon integrase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GIN1 mRNA CTD PMID:28903501 NCBI chr 9:98,293,596...98,315,155
Ensembl chr 9:98,293,597...98,315,848 		JBrowse link
G Gins2 GINS complex subunit 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GINS2 mRNA CTD PMID:22698814 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GJA1 mRNA CTD PMID:28903501 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja4 gap junction protein, alpha 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GJA4 mRNA CTD PMID:28903501 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925 		JBrowse link
G Gjb4 gap junction protein, beta 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GJB4 mRNA CTD PMID:28903501 NCBI chr 5:139,675,776...139,679,551
Ensembl chr 5:139,675,780...139,679,667 		JBrowse link
G Glipr2 GLI pathogenesis-related 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GLIPR2 mRNA CTD PMID:22698814 NCBI chr 5:58,170,417...58,200,947
Ensembl chr 5:58,170,425...58,202,272 		JBrowse link
G Gls2 glutaminase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GLS2 mRNA CTD PMID:19162173 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Glt1d1 glycosyltransferase 1 domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GLT1D1 mRNA CTD PMID:28903501 NCBI chr12:28,975,984...29,049,707
Ensembl chr12:28,975,988...29,049,695 		JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GLUD1 mRNA CTD PMID:19162173 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GLUL mRNA CTD PMID:19162173 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gmfb glia maturation factor, beta increases expression EXP Pregnenolone Carbonitrile results in increased expression of GMFB mRNA CTD PMID:19162173 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331 		JBrowse link
G Gnao1 G protein subunit alpha o1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GNAO1 mRNA CTD PMID:19162173 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus increases expression ISO Pregnenolone Carbonitrile results in increased expression of GNAS mRNA CTD PMID:22698814 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnb5 G protein subunit beta 5 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GNB5 mRNA CTD PMID:19162173 NCBI chr 8:76,076,227...76,104,151
Ensembl chr 8:76,073,306...76,105,069 		JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GNE mRNA CTD PMID:19162173 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499 		JBrowse link
G Gnl2 G protein nucleolar 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GNL2 mRNA CTD PMID:28903501 NCBI chr 5:137,293,141...137,318,528
Ensembl chr 5:137,293,081...137,318,526 		JBrowse link
G Gnl3 G protein nucleolar 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GNL3 mRNA CTD PMID:28903501 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of GNMT mRNA
Pregnenolone Carbonitrile results in increased expression of GNMT mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GNPDA1 mRNA CTD PMID:28903501 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486 		JBrowse link
G Golph3l golgi phosphoprotein 3-like increases expression ISO Pregnenolone Carbonitrile results in increased expression of GOLPH3L mRNA CTD PMID:22698814 NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083 		JBrowse link
G Gorasp1 golgi reassembly stacking protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GORASP1 mRNA CTD PMID:28903501 NCBI chr 8:119,655,267...119,667,022
Ensembl chr 8:119,655,268...119,666,972 		JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GOSR2 mRNA CTD PMID:19162173 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of GOT1 mRNA
Pregnenolone Carbonitrile results in increased expression of GOT1 mRNA		 CTD PMID:19162173 PMID:28903501 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GPAM mRNA CTD PMID:28903501 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpatch4 G patch domain containing 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPATCH4 mRNA CTD PMID:28903501 NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684 		JBrowse link
G Gpc4 glypican 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPC4 mRNA CTD PMID:28903501 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPCPD1 mRNA CTD PMID:28903501 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GPD1 mRNA CTD PMID:28903501 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GPD2 mRNA CTD PMID:19162173 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPT2 mRNA CTD PMID:27413110 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GPX1 mRNA CTD PMID:19162173 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GPX2 mRNA CTD PMID:19162173 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPX7 mRNA CTD PMID:22698814 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004 		JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GRB2 mRNA CTD PMID:28903501 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GRB7 mRNA CTD PMID:28903501 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A increases expression EXP Pregnenolone Carbonitrile results in increased expression of GRIN3A mRNA CTD PMID:19162173 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GRK5 mRNA CTD PMID:19162173 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701 		JBrowse link
G Grn granulin precursor increases expression ISO Pregnenolone Carbonitrile results in increased expression of GRN mRNA CTD PMID:28903501 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Grpel2 GrpE-like 2, mitochondrial decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GRPEL2 mRNA CTD PMID:28903501 NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180 		JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GRWD1 mRNA CTD PMID:28903501 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201 		JBrowse link
G Gsap gamma-secretase activating protein increases expression ISO Pregnenolone Carbonitrile results in increased expression of GSAP mRNA CTD PMID:28903501 NCBI chr 4:13,813,046...13,907,875
Ensembl chr 4:13,813,046...13,907,814 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of GSR mRNA CTD PMID:19162173 PMID:27413110 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression		 ISO NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA2 mRNA] CTD PMID:22698814 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GSTA3 mRNA CTD PMID:19162173 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GSTA4 mRNA CTD PMID:19162173 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in increased expression of GSTA1 mRNA
[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTA1 gene]] which results in increased expression of GSTA1 mRNA; [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTA1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTA1 gene]		 CTD PMID:20693526 PMID:22496397 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression		 ISO
EXP		 [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM1 5' UTR] CTD PMID:18723825 PMID:19162173 PMID:20693526 PMID:22496397 PMID:27413110 More... NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of GSTM2 mRNA
[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM2 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM2 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM2 gene]		 CTD PMID:18723825 PMID:19162173 PMID:20693526 PMID:22496397 PMID:27413110 More... NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GSTM4 mRNA CTD PMID:22496397 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM3 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM3 mRNA]
Pregnenolone Carbonitrile results in decreased expression of GSTM5 mRNA
Pregnenolone Carbonitrile results in increased expression of GSTM5 mRNA		 CTD PMID:18723825 PMID:19162173 PMID:22496397 PMID:27413110 PMID:28903501 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GTF2IRD1 mRNA CTD PMID:19162173 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040 		JBrowse link
G Gyg1 glycogenin 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GYG1 mRNA CTD PMID:19162173 NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797 		JBrowse link
G Gys2 glycogen synthase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GYS2 mRNA CTD PMID:19162173 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228 		JBrowse link
G H1f0 H1.0 linker histone decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of H1F0 mRNA CTD PMID:19162173 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694 		JBrowse link
G H1f10 H1.10 linker histone increases expression ISO Pregnenolone Carbonitrile results in increased expression of H1F10 mRNA CTD PMID:22698814 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448 		JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of H2AZ1 mRNA CTD PMID:19162173 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485 		JBrowse link
G H3f3b H3.3 histone B increases expression ISO Pregnenolone Carbonitrile results in increased expression of H3F3B mRNA CTD PMID:28903501 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hal histidine ammonia lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HAL mRNA CTD PMID:19162173 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of HAO2 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Pregnenolone Carbonitrile results in increased expression of HASPIN mRNA CTD PMID:22698814 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512 		JBrowse link
G Hdc histidine decarboxylase increases expression EXP Pregnenolone Carbonitrile results in increased expression of HDC mRNA CTD PMID:19162173 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Heatr1 HEAT repeat containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HEATR1 mRNA CTD PMID:28903501 NCBI chr17:58,051,700...58,093,895
Ensembl chr17:58,051,700...58,093,948 		JBrowse link
G Hectd2 HECT domain E3 ubiquitin protein ligase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HECTD2 mRNA CTD PMID:28903501 NCBI chr 1:234,274,967...234,345,598
Ensembl chr 1:234,275,705...234,343,487 		JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HERC2 mRNA CTD PMID:22698814 NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HERPUD1 mRNA CTD PMID:28903501 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HES1 mRNA CTD PMID:19162173 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HES6 mRNA CTD PMID:28903501 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559 		JBrowse link
G Hfe homeostatic iron regulator increases expression EXP Pregnenolone Carbonitrile results in increased expression of HFE mRNA CTD PMID:19162173 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hgf hepatocyte growth factor decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HGF mRNA CTD PMID:19162173 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hgfac HGF activator decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HGFAC mRNA CTD PMID:28903501 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278 		JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HHEX mRNA CTD PMID:28903501 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO Pregnenolone Carbonitrile results in increased expression of HIF3A mRNA CTD PMID:28903501 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HIGD1A mRNA CTD PMID:19162173 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hist2h2be histone cluster 2 H2B family member E decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of H2BC21 mRNA CTD PMID:28903501 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Hmg20b high mobility group 20 B increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMG20B mRNA CTD PMID:19162173 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640 		JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMGA2 mRNA CTD PMID:19162173 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMGB2 mRNA CTD PMID:19162173 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HMGCL mRNA CTD PMID:19162173 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression		 ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of HMGCR mRNA; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of HMGCR mRNA] CTD PMID:20359477 PMID:22698814 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions
decreases expression		 ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of HMGCS2 mRNA]
Pregnenolone Carbonitrile results in decreased expression of HMGCS2 mRNA		 CTD PMID:20359477 PMID:28903501 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMMR mRNA CTD PMID:19162173 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMOX1 mRNA CTD PMID:19162173 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hmox2 heme oxygenase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HMOX2 mRNA CTD PMID:28903501 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148 		JBrowse link
G Hnf1a HNF1 homeobox A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HNF1A mRNA CTD PMID:20888898 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
decreases expression
multiple interactions		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of HNF4A mRNA
Pregnenolone Carbonitrile results in decreased expression of HNF4A mRNA
[Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of HNF4A mRNA		 CTD PMID:19162173 PMID:20359477 PMID:20888898 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C increases expression EXP Pregnenolone Carbonitrile results in increased expression of HNRNPC mRNA CTD PMID:19162173 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HOMER1 mRNA CTD PMID:19162173 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hoxa2 homeobox A2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HOXA2 mRNA CTD PMID:22698814 Ensembl chr 4:81,262,768...81,265,044 JBrowse link
G Hp haptoglobin increases expression ISO Pregnenolone Carbonitrile results in increased expression of HP mRNA CTD PMID:28903501 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hpx hemopexin increases expression ISO Pregnenolone Carbonitrile results in increased expression of HPX mRNA CTD PMID:28903501 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression EXP Pregnenolone Carbonitrile results in increased expression of HRK mRNA CTD PMID:19162173 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSD11B1 mRNA CTD PMID:19162173 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD17B11 mRNA CTD PMID:27413110 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161 		JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD17B13 mRNA CTD PMID:28903501 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HSD17B2 mRNA CTD PMID:19162173 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HSD17B6 mRNA CTD PMID:19162173 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD3B3 mRNA CTD PMID:28903501 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033 		JBrowse link
G Hsf4 heat shock transcription factor 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSF4 mRNA CTD PMID:28903501 NCBI chr19:33,147,755...33,153,479
Ensembl chr19:33,147,755...33,153,479 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSP90AA1 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
multiple interactions		 ISO Pregnenolone Carbonitrile results in decreased expression of HSPA1B mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of HSPA1B mRNA]		 CTD PMID:22698814 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSPA8 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb6 heat shock protein family B (small) member 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HSPB6 mRNA CTD PMID:19162173 NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSPD1 mRNA CTD PMID:19162173 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSPH1 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HTR4 mRNA CTD PMID:19162173 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Htt huntingtin increases expression EXP Pregnenolone Carbonitrile results in increased expression of HTT mRNA CTD PMID:19162173 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HYOU1 mRNA CTD PMID:19162173 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ID1 mRNA CTD PMID:19162173 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ID2 mRNA CTD PMID:19162173 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of IDH2 mRNA CTD PMID:28903501 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of IER3 mRNA CTD PMID:22698814 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of IFITM2 mRNA CTD PMID:28903501 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741 		JBrowse link
G Ifitm5 interferon induced transmembrane protein 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of IFITM5 mRNA CTD PMID:28903501 NCBI chr 1:196,045,836...196,052,554
Ensembl chr 1:196,045,666...196,047,232 		JBrowse link
G Ifnar2 interferon alpha and beta receptor subunit 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of IFNAR2 mRNA CTD PMID:28903501 NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of IGF1 mRNA CTD PMID:19162173 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of IGFALS mRNA CTD PMID:19162173 PMID:28903501 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression
increases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in decreased expression of IGFBP1 mRNA
Pregnenolone Carbonitrile results in increased expression of IGFBP1 mRNA		 CTD PMID:19162173 PMID:22698814 PMID:27413110 PMID:28903501 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression
decreases expression		 EXP
ISO		 Pregnenolone Carbonitrile results in increased expression of IGFBP2 mRNA
Pregnenolone Carbonitrile results in decreased expression of IGFBP2 mRNA		 CTD PMID:19162173 PMID:21318169 PMID:27413110 PMID:28903501 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G IgG-2a