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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pregnenolone
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Accession:CHEBI:16581 term browser browse the term
Definition:A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.
Synonyms:related_synonym: (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE;   3beta-Hydroxypregn-5-en-20-one;   5-Pregnen-3beta-ol-20-one;   Formula=C21H32O2;   InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19,23H,5-12H2,1-3H3/t15-,16-,17+,18-,19-,20-,21+/m0/s1;   InChIKey=ORNBQBCIOKFOEO-QGVNFLHTSA-N;   SMILES=[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O
 alt_id: CHEBI:14881;   CHEBI:26241;   CHEBI:45027;   CHEBI:8388;   CHEBI:86573
 xref: Beilstein:2059026;   CAS:145-13-1;   DrugBank:DB02789;   HMDB:HMDB0000253;   KEGG:C01953;   KEGG:D00143;   LINCS:LSM-5550;   LIPID_MAPS_instance:LMST02030088
 xref_mesh: MESH:D011284
 xref: PDBeChem:PLO;   PMID:23572091;   PMID:24385629;   Reaxys:2059026;   Wikipedia:Pregnenolone


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pregnenolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor decreases activity ISO Pregnenolone results in decreased activity of AHR protein CTD PMID:30203046 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G App amyloid beta precursor protein decreases response to substance EXP Pregnenolone results in decreased susceptibility to APP protein modified form CTD PMID:18926803 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions EXP Pregnenolone inhibits the reaction [Acetylcholine binds to CHRM1 protein]; Pregnenolone inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM1 protein] CTD PMID:15900516 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions EXP Pregnenolone inhibits the reaction [Acetylcholine binds to CHRM3 protein]; Pregnenolone inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM3 protein] CTD PMID:15900516 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases activity ISO Pregnenolone results in decreased activity of CNR1 protein CTD PMID:28220044 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases chemical synthesis
multiple interactions
ISO
EXP
CYP11A1 protein results in increased chemical synthesis of Pregnenolone
[Diethylstilbestrol results in decreased expression of CYP11A1 protein] which results in decreased chemical synthesis of Pregnenolone
CTD PMID:16054388 PMID:19900470 PMID:23873838 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects metabolic processing
increases hydroxylation
multiple interactions
ISO
EXP
CYP17A1 protein affects the metabolism of Pregnenolone
CYP17A1 protein mutant form results in increased hydroxylation of Pregnenolone; CYP17A1 protein results in increased hydroxylation of Pregnenolone
[[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; [abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone; [CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]
Plant Extracts inhibits the reaction [Pregnenolone binds to CYP17A1 protein]
CTD PMID:15562394 PMID:15666820 PMID:15844475 PMID:16030167 PMID:16054388 More... NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Pregnenolone results in increased expression of CYP3A4 mRNA; Pregnenolone results in increased expression of CYP3A4 protein CTD PMID:15650019 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases activity EXP Pregnenolone results in decreased activity of CYP7A1 protein CTD PMID:1175606 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO ESR1 protein affects the reaction [Pregnenolone results in increased expression of GREB1 mRNA] CTD PMID:33405908 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions ISO FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO [FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone; FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions
increases expression
ISO ESR1 protein affects the reaction [Pregnenolone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of GREB1 mRNA] CTD PMID:33405908 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Pregnenolone results in increased expression of GSTA2 mRNA CTD PMID:11502894 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO Pregnenolone inhibits the reaction [25-hydroxycholesterol results in decreased activity of HMGCR protein]; Pregnenolone inhibits the reaction [27-hydroxycholesterol results in decreased activity of HMGCR protein] CTD PMID:9059514 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 increases expression ISO Pregnenolone results in increased expression of HSD17B1 mRNA CTD PMID:20956811 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects metabolic processing ISO HSD3B1 protein affects the metabolism of Pregnenolone CTD PMID:16054388 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions
increases metabolic processing
ISO [HSD3B2 protein results in increased metabolism of Pregnenolone] which results in increased abundance of Progesterone CTD PMID:21558439 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone; FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases abundance
EXP 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; benoxaprofen inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; Masoprocol inhibits the reaction [LHB protein results in increased abundance of Pregnenolone] CTD PMID:6430271 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Mybl1 MYB proto-oncogene like 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of MYBL1 mRNA] CTD PMID:33405908 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO Pregnenolone results in increased activity of NFE2L2 protein CTD PMID:30203046 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO Pregnenolone binds to and results in increased activity of NR1I2 protein
Pregnenolone results in increased activity of NR1I2 protein
CTD PMID:15650019 PMID:16054614 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Pregnenolone results in increased activity of NR1I3 protein CTD PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression
multiple interactions
ISO Pregnenolone results in increased expression of SGK1 mRNA
Fulvestrant inhibits the reaction [Pregnenolone results in increased expression of SGK1 mRNA]
CTD PMID:33405908 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sigmar1 sigma non-opioid intracellular receptor 1 increases abundance ISO SIGMAR1 protein results in increased abundance of Pregnenolone CTD PMID:22923735 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
JBrowse link
17alpha-hydroxypregnenolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects chemical synthesis
increases metabolic processing
multiple interactions
affects metabolic processing
decreases acetylation
ISO CYP17A1 protein affects the chemical synthesis of 17-alpha-Hydroxypregnenolone
CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone
[[abiraterone results in decreased activity of CYP17A1 protein] which results in decreased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; [CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone; [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Duloxetine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Duloxetine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]
CYP17A1 protein affects the metabolism of 17-alpha-Hydroxypregnenolone
CYP17A1 protein results in decreased acetylation of 17-alpha-Hydroxypregnenolone
CTD PMID:15562394 PMID:16030167 PMID:17194026 PMID:29100959 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
pregnenolone 16alpha-carbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase increases expression
decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in increased expression of AACS mRNA
Pregnenolone Carbonitrile results in decreased expression of AACS mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of AACS mRNA]
CTD PMID:22698814 PMID:28903501 NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
JBrowse link
G Aadac arylacetamide deacetylase decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of AADAC mRNA
NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in decreased expression of AADAC mRNA]
CTD PMID:22429928 PMID:28903501 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
JBrowse link
G Aadat aminoadipate aminotransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AADAT mRNA CTD PMID:19162173 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Aass aminoadipate-semialdehyde synthase increases expression ISO Pregnenolone Carbonitrile results in increased expression of AASS mRNA CTD PMID:28903501 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136
JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ABAT mRNA CTD PMID:19162173 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ABCA1 mRNA; Pregnenolone Carbonitrile results in decreased expression of ABCA1 protein CTD PMID:15883047 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
increases expression
ISO Endotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB11 mRNA] CTD PMID:15456840 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
ISO
EXP
Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]; NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA]; NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCB1 protein]
Pregnenolone Carbonitrile results in increased expression of ABCB1A mRNA
Pregnenolone Carbonitrile results in increased expression of ABCB1 mRNA; Pregnenolone Carbonitrile results in increased expression of ABCB1 protein; Pregnenolone Carbonitrile results in increased expression of ABCB1A mRNA
CTD PMID:15456840 PMID:16819505 PMID:19162173 PMID:29863087 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABCB1B mRNA CTD PMID:29863087 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
decreases expression
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of ABCB4 mRNA
Pregnenolone Carbonitrile results in decreased expression of ABCB4 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 multiple interactions ISO ABCB6 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA] CTD PMID:25623066 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ABCC1 mRNA CTD PMID:11752103 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
ISO
EXP
[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of ABCC2 mRNA; Endotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA]
Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA; Pregnenolone Carbonitrile results in increased expression of ABCC2 protein
CTD PMID:15456840 PMID:15917434 PMID:19118567 PMID:19162173 PMID:20888898 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases expression
increases activity
ISO
EXP
[Pregnenolone Carbonitrile binds to NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]] which results in increased expression of ABCC3 mRNA; [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC3 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ABCC3 gene]
Pregnenolone Carbonitrile results in increased expression of ABCC3 mRNA; Pregnenolone Carbonitrile results in increased expression of ABCC3 protein
Pregnenolone Carbonitrile results in increased activity of ABCC3 protein
CTD PMID:14570758 PMID:15456840 PMID:15833929 PMID:15986414 PMID:19162173 More... NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects expression ISO Pregnenolone Carbonitrile affects the expression of ABCC4 mRNA CTD PMID:31388680 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABCD4 mRNA CTD PMID:28903501 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of ABCG5 mRNA
[Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of ABCG5 mRNA
CTD PMID:15683829 PMID:20359477 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ABCG8 mRNA CTD PMID:15683829 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Abhd14b abhydrolase domain containing 14b decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ABHD14B mRNA CTD PMID:28903501 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Abhd17b abhydrolase domain containing 17B, depalmitoylase increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABHD17B mRNA CTD PMID:22698814 NCBI chr 1:219,198,294...219,232,733
Ensembl chr 1:219,198,471...219,231,933
JBrowse link
G Ablim1 actin-binding LIM protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABLIM1 mRNA CTD PMID:28903501 NCBI chr 1:256,084,293...256,372,075 JBrowse link
G Ablim3 actin binding LIM protein family, member 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ABLIM3 mRNA CTD PMID:28903501 NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380
JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression
decreases expression
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of ABTB2 mRNA
Pregnenolone Carbonitrile results in decreased expression of ABTB2 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACAA1B mRNA CTD PMID:28903501 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ACAA2 mRNA CTD PMID:19162173 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of ACACA mRNA] CTD PMID:20359477 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACAT1 mRNA CTD PMID:19162173 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of ACAT2 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acbd4 acyl-CoA binding domain containing 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACBD4 mRNA CTD PMID:28903501 NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500
JBrowse link
G Acbd5 acyl-CoA binding domain containing 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACBD5 mRNA CTD PMID:28903501 NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACER2 mRNA CTD PMID:28903501 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Acly ATP citrate lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACLY mRNA CTD PMID:19162173 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco2 aconitase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACO2 mRNA CTD PMID:28903501 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acod1 aconitate decarboxylase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACOD1 mRNA CTD PMID:22698814 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACOT1 mRNA CTD PMID:19162173 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot2 acyl-CoA thioesterase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACOT2 mRNA CTD PMID:19162173 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot3 acyl-CoA thioesterase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACOT3 mRNA CTD PMID:27413110 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,723,326...103,729,482
JBrowse link
G Acot4 acyl-CoA thioesterase 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACOT4 mRNA CTD PMID:28903501 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Acot6 acyl-CoA thioesterase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACOT6 mRNA CTD PMID:22698814 NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACOX1 mRNA CTD PMID:28903501 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACOX2 mRNA CTD PMID:19162173 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of ACSL1 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of ACSL1 mRNA]
CTD PMID:19162173 PMID:20359477 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSL4 mRNA CTD PMID:28903501 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSL5 mRNA CTD PMID:28903501 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of ACSM2A mRNA
Pregnenolone Carbonitrile results in increased expression of ACSM2 mRNA
CTD PMID:19162173 PMID:22698814 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ACSM3 mRNA CTD PMID:19162173 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Acsm5 acyl-CoA synthetase medium-chain family member 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSM5 mRNA CTD PMID:28903501 NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACSS2 mRNA CTD PMID:28903501 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Pregnenolone Carbonitrile results in increased expression of ACTA2 mRNA CTD PMID:28903501 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actg1 actin, gamma 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ACTG1 mRNA CTD PMID:19162173 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Acy3 aminoacylase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ACY3 mRNA CTD PMID:28903501 NCBI chr 1:201,279,751...201,285,803
Ensembl chr 1:201,279,851...201,283,175
JBrowse link
G Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADAMTS14 mRNA CTD PMID:28903501 NCBI chr20:29,143,029...29,219,846
Ensembl chr20:29,144,354...29,219,866
JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADAMTS15 mRNA CTD PMID:28903501 NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
JBrowse link
G Adamtsl2 ADAMTS-like 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADAMTSL2 mRNA CTD PMID:28903501 NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADARB1 mRNA CTD PMID:28903501 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
JBrowse link
G Adck5 aarF domain containing kinase 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADCK5 mRNA CTD PMID:28903501 NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436
JBrowse link
G Adcy1 adenylate cyclase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ADCY1 mRNA CTD PMID:28903501 NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969
JBrowse link
G Add1 adducin 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ADD1 mRNA CTD PMID:19162173 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of ADH1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADH4 mRNA CTD PMID:28903501 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADH7 mRNA CTD PMID:28903501 NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADHFE1 mRNA CTD PMID:27413110 NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ADRB3 mRNA CTD PMID:28903501 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO Pregnenolone Carbonitrile results in increased expression of AEN mRNA CTD PMID:28903501 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Afm afamin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AFM mRNA CTD PMID:28903501 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Afp alpha-fetoprotein decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of AFP mRNA
[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of AFP mRNA
CTD PMID:27413110 PMID:28903501 PMID:33398415 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AGER mRNA CTD PMID:19162173 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ago1 argonaute RISC component 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of AGO1 mRNA CTD PMID:22698814 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AGXT mRNA CTD PMID:19162173 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Ahcy adenosylhomocysteinase increases expression ISO Pregnenolone Carbonitrile results in increased expression of AHCY mRNA CTD PMID:28903501 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR mRNA]] CTD PMID:28428138 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AIF1 mRNA CTD PMID:19162173 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AIFM2 mRNA CTD PMID:19162173 NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AIFM3 mRNA CTD PMID:28903501 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248
JBrowse link
G Akap17a A-kinase anchoring protein 17A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AKAP17B mRNA CTD PMID:28903501 NCBI chr12:16,310,427...16,315,166
Ensembl chr12:16,310,437...16,314,479
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in increased expression of AKR1B7 mRNA
NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of AKR1B7 mRNA]
CTD PMID:25949234 PMID:27413110 PMID:28903501 NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AKR1C6 mRNA CTD PMID:28903501 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of AKR1D1 mRNA CTD PMID:28903501 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of AKR7A3 mRNA CTD PMID:19162173 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of ALAS1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of ALDH1A1 mRNA
[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ALDH1A1 intron]] which results in increased expression of ALDH1A1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of ALDH1A1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to ALDH1A1 intron]
CTD PMID:17998271 PMID:19162173 PMID:20693526 PMID:22496397 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDH1B1 mRNA CTD PMID:17998271 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression
decreases expression
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of ALDH1L1 mRNA
Pregnenolone Carbonitrile results in decreased expression of ALDH1L1 mRNA
CTD PMID:19162173 PMID:27413110 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ALDH3A2 mRNA CTD PMID:28903501 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDH4A1 mRNA CTD PMID:28903501 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ALDH6A1 mRNA CTD PMID:27413110 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDH8A1 mRNA CTD PMID:17998271 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression ISO Pregnenolone Carbonitrile results in increased expression of ALDOB mRNA CTD PMID:22698814 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ALOX5 mRNA CTD PMID:22698814 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AMACR mRNA CTD PMID:19162173 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression ISO Pregnenolone Carbonitrile results in increased expression of AMBP mRNA CTD PMID:28903501 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog increases expression ISO Pregnenolone Carbonitrile results in increased expression of AMN1 mRNA CTD PMID:28903501 NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016
JBrowse link
G Amph amphiphysin increases expression EXP Pregnenolone Carbonitrile results in increased expression of AMPH mRNA CTD PMID:19162173 NCBI chr17:45,739,385...45,982,905 JBrowse link
G Amt aminomethyltransferase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AMT mRNA CTD PMID:28903501 NCBI chr 8:108,981,620...108,988,127
Ensembl chr 8:108,976,472...108,988,126
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ANGPTL4 mRNA CTD PMID:28903501 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ankib1 ankyrin repeat and IBR domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ANKIB1 mRNA CTD PMID:28903501 NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781
JBrowse link
G Ankle1 ankyrin repeat and LEM domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ANKLE1 mRNA CTD PMID:22698814 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729
JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ANKRD24 mRNA CTD PMID:19162173 NCBI chr 7:8,061,634...8,081,142
Ensembl chr 7:8,061,953...8,081,142
JBrowse link
G Anks4b ankyrin repeat and sterile alpha motif domain containing 4B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ANKS4B mRNA CTD PMID:28903501 NCBI chr 1:174,534,195...174,557,798
Ensembl chr 1:174,547,473...174,557,797
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ANPEP mRNA CTD PMID:19162173 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Anxa2 annexin A2 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA2 mRNA] CTD PMID:20359477 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa3 annexin A3 decreases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of ANXA3 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA3 mRNA]
CTD PMID:19162173 PMID:20359477 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa4 annexin A4 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA4 mRNA] CTD PMID:20359477 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of ANXA5 mRNA] CTD PMID:20359477 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of AP3M1 mRNA CTD PMID:19162173 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Apba3 amyloid beta precursor protein binding family A member 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of APBA3 mRNA CTD PMID:19162173 NCBI chr 7:8,446,212...8,451,310
Ensembl chr 7:8,446,216...8,451,241
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of APBB3 mRNA CTD PMID:28903501 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Apcs amyloid P component, serum increases expression ISO Pregnenolone Carbonitrile results in increased expression of APCS mRNA CTD PMID:28903501 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of APEX1 mRNA
Pregnenolone Carbonitrile results in increased expression of APEX1 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
JBrowse link
G Aplp2 amyloid beta precursor like protein 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APLP2 mRNA CTD PMID:19162173 NCBI chr 8:29,599,230...29,662,311
Ensembl chr 8:29,599,230...29,661,855
JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of APOA1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APOBEC1 mRNA CTD PMID:19162173 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390
JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APOC3 mRNA CTD PMID:19162173 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Apoc4 apolipoprotein C4 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of APOC4 mRNA CTD PMID:19162173 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
JBrowse link
G Apol3 apolipoprotein L, 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of APOL9B mRNA CTD PMID:28903501 NCBI chr 7:109,288,725...109,297,728
Ensembl chr 7:109,288,725...109,297,723
JBrowse link
G Apol9a apolipoprotein L 9a decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of APOL9A mRNA CTD PMID:28903501 NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649
JBrowse link
G App amyloid beta precursor protein increases expression EXP Pregnenolone Carbonitrile results in increased expression of APP mRNA CTD PMID:19162173 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AQP4 mRNA CTD PMID:28903501 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Aqp7 aquaporin 7 increases expression EXP Pregnenolone Carbonitrile results in increased expression of AQP7 mRNA CTD PMID:19162173 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of AQP8 mRNA CTD PMID:28903501 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Aqp9 aquaporin 9 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AQP9 mRNA CTD PMID:19162173 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Ar androgen receptor increases expression EXP Pregnenolone Carbonitrile results in increased expression of AR mRNA CTD PMID:19162173 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARHGAP29 mRNA CTD PMID:28903501 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARHGEF16 mRNA CTD PMID:28903501 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212
JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARHGEF19 mRNA CTD PMID:28903501 NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARHGEF26 mRNA CTD PMID:28903501 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819
JBrowse link
G Arhgef3 Rho guanine nucleotide exchange factor 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARHGEF3 mRNA CTD PMID:28903501 NCBI chr16:2,301,573...2,581,951
Ensembl chr16:2,300,138...2,581,945
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARID5A mRNA CTD PMID:28903501 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Arl4a ADP-ribosylation factor like GTPase 4A increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARL4A mRNA CTD PMID:28903501 NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066
JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A increases expression EXP Pregnenolone Carbonitrile results in increased expression of ARL5A mRNA CTD PMID:19162173 NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARNTL mRNA CTD PMID:27413110 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Arrb1 arrestin, beta 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ARRB1 mRNA CTD PMID:28903501 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARRDC3 mRNA CTD PMID:28903501 NCBI chr 2:11,137,443...11,149,978
Ensembl chr 2:11,137,460...11,149,978
JBrowse link
G Arsa arylsulfatase A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ARSA mRNA CTD PMID:28903501 NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783
JBrowse link
G Asb13 ankyrin repeat and SOCS box-containing 13 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ASB13 mRNA CTD PMID:28903501 NCBI chr17:66,564,653...66,583,365
Ensembl chr17:66,562,434...66,583,337
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO Pregnenolone Carbonitrile results in increased expression of ASF1B mRNA CTD PMID:22698814 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Asl argininosuccinate lyase increases expression ISO Pregnenolone Carbonitrile results in increased expression of ASL mRNA CTD PMID:28903501 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Pregnenolone Carbonitrile results in increased expression of ASNS mRNA CTD PMID:27413110 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ASPRV1 mRNA CTD PMID:22698814 NCBI chr 4:119,076,169...119,078,887
Ensembl chr 4:119,077,356...119,078,379
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ASS1 mRNA CTD PMID:19162173 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATAD1 mRNA CTD PMID:28903501 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548
JBrowse link
G Atad3a ATPase family, AAA domain containing 3A increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATAD3A mRNA CTD PMID:28903501 NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482
JBrowse link
G Atat1 alpha tubulin acetyltransferase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ATAT1 mRNA CTD PMID:28903501 NCBI chr20:2,844,595...2,857,809
Ensembl chr20:2,844,616...2,861,964
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
decreases expression
ISO NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of ATF3 mRNA] CTD PMID:22698814 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atg14 autophagy related 14 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATG14 mRNA CTD PMID:28903501 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atl2 atlastin GTPase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATL2 mRNA CTD PMID:28903501 NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421
JBrowse link
G Atp10d ATPase phospholipid transporting 10D (putative) increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP10D mRNA CTD PMID:28903501 NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ATP1B1 mRNA CTD PMID:19162173 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp4a ATPase H+/K+ transporting subunit alpha increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP4A mRNA CTD PMID:22698814 NCBI chr 1:85,961,607...85,974,972
Ensembl chr 1:85,961,708...85,974,844
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ATPIF1 mRNA CTD PMID:19162173 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP5K mRNA CTD PMID:28903501 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ATP6V0A4 mRNA CTD PMID:28903501 NCBI chr 4:66,760,159...66,842,110
Ensembl chr 4:66,760,159...66,842,110
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP Pregnenolone Carbonitrile results in increased expression of ATP6V1D mRNA CTD PMID:19162173 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G Atrn attractin decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ATRN mRNA CTD PMID:19162173 NCBI chr 3:118,110,320...118,244,326
Ensembl chr 3:118,110,229...118,244,322
JBrowse link
G Atxn7l1 ataxin 7-like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ATXN7L1 mRNA CTD PMID:28903501 NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of AVPR1A mRNA CTD PMID:19162173 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Axin2 axin 2 multiple interactions ISO [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of AXIN2 mRNA CTD PMID:33398415 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G B3galt1 Beta-1,3-galactosyltransferase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of B3GALT1 mRNA CTD PMID:28903501 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313
JBrowse link
G B3gntl1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of B3GNTL1 mRNA CTD PMID:19162173 NCBI chr10:106,870,237...106,933,723
Ensembl chr10:106,873,169...106,933,637
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of B4GALT1 mRNA CTD PMID:28903501 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase increases expression ISO Pregnenolone Carbonitrile results in increased expression of BAAT mRNA CTD PMID:27413110 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of BAD mRNA CTD PMID:19162173 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BAIAP2 mRNA CTD PMID:28903501 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of BAK1 protein CTD PMID:19433268 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of BAX protein CTD PMID:19433268 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCAT2 mRNA CTD PMID:28903501 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
JBrowse link
G Bche butyrylcholinesterase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCHE mRNA CTD PMID:28903501 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Pregnenolone Carbonitrile results in increased expression of BCL2 mRNA CTD PMID:19162173 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCL2A1B mRNA CTD PMID:22698814 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased expression of BCL2L1 mRNA]
Pregnenolone Carbonitrile results in increased expression of BCL2L1 mRNA
CTD PMID:19433268 PMID:28903501 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bco2 beta-carotene oxygenase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BCO2 mRNA CTD PMID:28903501 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Bcor BCL6 co-repressor increases expression ISO Pregnenolone Carbonitrile results in increased expression of BCOR mRNA CTD PMID:28903501 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BDH1 mRNA CTD PMID:28903501 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase increases expression ISO Pregnenolone Carbonitrile results in increased expression of BHMT mRNA CTD PMID:28903501 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bin1 bridging integrator 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of BIN1 mRNA CTD PMID:19162173 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in increased expression of BIRC5 mRNA
[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNA
CTD PMID:22698814 PMID:28903501 PMID:33398415 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bivm basic, immunoglobulin-like variable motif containing decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of BIVM mRNA CTD PMID:28903501 NCBI chr 9:46,268,758...46,305,038
Ensembl chr 9:46,269,252...46,305,024
JBrowse link
G Bmper BMP-binding endothelial regulator increases expression ISO Pregnenolone Carbonitrile results in increased expression of BMPER mRNA CTD PMID:28903501 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BNIP3 mRNA CTD PMID:28903501 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP Pregnenolone Carbonitrile results in increased expression of BNIP3L mRNA CTD PMID:19162173 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of BRCA1 mRNA CTD PMID:23626729 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of BRCA2 mRNA CTD PMID:23626729 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of BRCC3 mRNA CTD PMID:19162173 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Brix1 biogenesis of ribosomes BRX1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BRIX1 mRNA CTD PMID:28903501 NCBI chr 2:59,450,608...59,461,486
Ensembl chr 2:59,450,614...59,461,495
JBrowse link
G Btf3 basic transcription factor 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of BTF3 mRNA CTD PMID:28903501 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G C1qb complement C1q B chain decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of C1QB mRNA CTD PMID:19162173 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G C1r complement C1r decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of C1R mRNA CTD PMID:19162173 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
JBrowse link
G C3 complement C3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of C3 mRNA CTD PMID:28903501 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C4a complement C4A increases expression ISO Pregnenolone Carbonitrile results in increased expression of C4A mRNA CTD PMID:28903501 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CAR14 mRNA CTD PMID:28903501 NCBI chr 2:183,442,263...183,449,207
Ensembl chr 2:183,441,667...183,449,693
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CAR3 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CAR9 mRNA CTD PMID:22698814 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D increases expression ISO Pregnenolone Carbonitrile results in increased expression of CACNA1D mRNA CTD PMID:22698814 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CACNB4 mRNA CTD PMID:28903501 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CAMK2N1 mRNA CTD PMID:19162173 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CAMKK2 mRNA CTD PMID:19162173 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279
JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CAMSAP2 mRNA CTD PMID:22698814 NCBI chr13:47,723,121...47,802,597
Ensembl chr13:47,723,121...47,802,597
JBrowse link
G Casp1 caspase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CASP1 mRNA CTD PMID:19162173 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CASP3 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in increased cleavage of CASP3 protein]
CTD PMID:19162173 PMID:19433268 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp6 caspase 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CASP6 mRNA CTD PMID:19162173 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Cavin3 caveolae associated protein 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CAVIN3 mRNA CTD PMID:19162173 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161
JBrowse link
G Cbx2 chromobox 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CBX2 mRNA CTD PMID:28903501 NCBI chr10:104,278,517...104,287,384
Ensembl chr10:104,278,549...104,287,383
JBrowse link
G Cbx4 chromobox 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CBX4 mRNA CTD PMID:28903501 NCBI chr10:104,337,140...104,343,210 JBrowse link
G Cbx5 chromobox 5 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CBX5 mRNA CTD PMID:19162173 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
JBrowse link
G Cbx8 chromobox 8 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CBX8 mRNA CTD PMID:28903501 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CC2D2A mRNA CTD PMID:28903501 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCDC86 mRNA CTD PMID:28903501 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of CCL2 mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of CCL2 mRNA]
CTD PMID:22698814 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCL6 mRNA CTD PMID:28903501 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001
JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of CCN1 mRNA
[Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of CYR61 mRNA
CTD PMID:28903501 PMID:33398415 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCN2 mRNA CTD PMID:28903501 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA; [pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNA2 mRNA; [Pregnenolone Carbonitrile co-treated with Phenobarbital] results in increased expression of CCNA2 mRNA CTD PMID:23626729 PMID:33398415 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CCNB1 mRNA
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA; [pirinixic acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB1 mRNA
CTD PMID:19162173 PMID:23626729 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CCNB2 mRNA CTD PMID:23626729 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CCND1 mRNA CTD PMID:19162173 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnf cyclin F decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CCNF mRNA CTD PMID:28903501 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCT2 mRNA CTD PMID:28903501 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CCT3 mRNA CTD PMID:28903501 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757
JBrowse link
G Cd19 CD19 molecule decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CD19 mRNA CTD PMID:28903501 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
JBrowse link
G Cd22 CD22 molecule decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CD22 mRNA CTD PMID:28903501 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322
JBrowse link
G Cd36 CD36 molecule decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CD36 mRNA CTD PMID:19162173 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd74 CD74 molecule decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CD74 mRNA CTD PMID:19162173 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd81 Cd81 molecule decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CD81 mRNA CTD PMID:19162173 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cd82 Cd82 molecule increases expression EXP Pregnenolone Carbonitrile results in increased expression of CD82 mRNA CTD PMID:19162173 NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
JBrowse link
G Cdc14b cell division cycle 14B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CDC14B mRNA CTD PMID:28903501 NCBI chr17:844,731...934,787
Ensembl chr17:844,685...933,235
JBrowse link
G Cdc20 cell division cycle 20 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CDC20 mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CDC20 mRNA]
CTD PMID:19162173 PMID:21318169 PMID:22698814 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDC45 mRNA CTD PMID:22698814 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDCA3 mRNA CTD PMID:22698814 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDCA8 mRNA CTD PMID:22698814 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdh15 cadherin 15 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDH15 mRNA CTD PMID:28903501 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
JBrowse link
G Cdh2 cadherin 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CDH2 mRNA CTD PMID:19162173 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdhr5 cadherin-related family member 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDHR5 mRNA CTD PMID:28903501 NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543
JBrowse link
G Cdip1 cell death-inducing p53 target 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDIP1 mRNA CTD PMID:28903501 NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in increased expression of CDK1 mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CDK1 mRNA]
CTD PMID:22698814 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk18 cyclin-dependent kinase 18 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDK18 mRNA CTD PMID:28903501 NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDKN1A mRNA CTD PMID:28903501 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CDKN3 mRNA CTD PMID:22698814 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CDO1 mRNA CTD PMID:19162173 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CEBPA mRNA CTD PMID:28903501 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CEBPB mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO Pregnenolone Carbonitrile results in increased expression of CEBPD mRNA CTD PMID:28903501 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cebpzos CEBPZ opposite strand increases expression ISO Pregnenolone Carbonitrile results in increased expression of CEBPZOS mRNA CTD PMID:28903501 NCBI chr 6:16,135,546...16,140,254 JBrowse link
G Celf1 CUGBP, Elav-like family member 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CELF1 mRNA CTD PMID:19162173 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
JBrowse link
G Cenpe centromere protein E increases expression ISO Pregnenolone Carbonitrile results in increased expression of CENPE mRNA CTD PMID:22698814 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenph centromere protein H increases expression ISO Pregnenolone Carbonitrile results in increased expression of CENPH mRNA CTD PMID:22698814 NCBI chr 2:31,894,253...31,910,182
Ensembl chr 2:31,894,667...31,910,154
JBrowse link
G Cenpp centromere protein P increases expression ISO Pregnenolone Carbonitrile results in increased expression of CENPP mRNA CTD PMID:22698814 NCBI chr17:15,013,869...15,189,312
Ensembl chr17:15,014,058...15,189,304
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases expression
ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CES1D mRNA]
Pregnenolone Carbonitrile results in increased expression of CES1D mRNA; Pregnenolone Carbonitrile results in increased expression of CES1D protein
CTD PMID:20359477 PMID:26179144 PMID:28903501 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2c carboxylesterase 2C multiple interactions
increases expression
ISO NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CES2C mRNA] CTD PMID:22429928 PMID:26179144 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Pregnenolone Carbonitrile results in increased expression of CES2 mRNA CTD PMID:19162173 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Ces3a carboxylesterase 3a decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CES3B mRNA CTD PMID:28903501 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cgn cingulin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CGN mRNA CTD PMID:28903501 NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645
JBrowse link
G Ch25h cholesterol 25-hydroxylase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CH25H mRNA CTD PMID:22698814 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CHAC2 mRNA CTD PMID:28903501 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A increases expression
decreases expression
ISO Pregnenolone Carbonitrile results in increased expression of CHAF1A mRNA
Pregnenolone Carbonitrile results in decreased expression of CHAF1A mRNA
CTD PMID:22698814 PMID:28903501 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
JBrowse link
G Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHCHD4 mRNA CTD PMID:28903501 NCBI chr 4:123,968,264...123,977,398
Ensembl chr 4:123,968,265...123,977,414
JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHCHD6 mRNA CTD PMID:19162173 NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHD1L mRNA CTD PMID:28903501 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CHEK1 mRNA CTD PMID:23626729 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chka choline kinase alpha decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CHKA mRNA CTD PMID:28903501 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHORDC1 mRNA CTD PMID:19162173 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Chpt1 choline phosphotransferase 1 multiple interactions ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of CHPT1 mRNA CTD PMID:20359477 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHRM1 mRNA CTD PMID:19162173 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CHRM3 mRNA CTD PMID:19162173 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chst15 carbohydrate sulfotransferase 15 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHST15 mRNA CTD PMID:28903501 NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707
JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CHTF18 mRNA CTD PMID:22698814 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050
JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CIAO1 mRNA CTD PMID:19162173 NCBI chr 3:114,458,671...114,465,928
Ensembl chr 3:114,458,655...114,467,009
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP Pregnenolone Carbonitrile results in increased expression of CIDEA mRNA CTD PMID:19162173 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CIITA mRNA CTD PMID:22698814 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CITED2 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
JBrowse link
G Ckb creatine kinase B decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CKB mRNA CTD PMID:19162173 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CKS1B mRNA CTD PMID:23626729 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CKS2 mRNA CTD PMID:28903501 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn14 claudin 14 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CLDN14 mRNA CTD PMID:28903501 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
JBrowse link
G Cldn3 claudin 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CLDN3 mRNA CTD PMID:19162173 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Clec4d C-type lectin domain family 4, member D decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CLEC4D mRNA CTD PMID:22698814 NCBI chr 4:156,589,591...156,598,969
Ensembl chr 4:156,589,792...156,598,848
JBrowse link
G Clec9a C-type lectin domain containing 9A increases expression ISO Pregnenolone Carbonitrile results in increased expression of CLEC9A mRNA CTD PMID:28903501 NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352
JBrowse link
G Clic3 chloride intracellular channel 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CLIC3 mRNA CTD PMID:28903501 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018
JBrowse link
G Clstn3 calsyntenin 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CLSTN3 mRNA CTD PMID:28903501 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
JBrowse link
G Cltb clathrin, light chain B increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CLTB mRNA CTD PMID:19162173 PMID:28903501 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
JBrowse link
G Clu clusterin increases expression ISO Pregnenolone Carbonitrile results in increased expression of CLU mRNA CTD PMID:28903501 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CNRIP1 mRNA CTD PMID:22698814 NCBI chr14:91,463,046...91,492,736
Ensembl chr14:91,462,647...91,492,735
JBrowse link
G Cntn5 contactin 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CNTN5 mRNA CTD PMID:22698814 NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957
JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of COL15A1 mRNA CTD PMID:28903501 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Colgalt2 collagen beta(1-O)galactosyltransferase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of COLGALT2 mRNA CTD PMID:22698814 PMID:28903501 NCBI chr13:64,523,641...64,628,295
Ensembl chr13:64,523,658...64,627,549
JBrowse link
G Comt catechol-O-methyltransferase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of COMT mRNA CTD PMID:19162173 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Coro2a coronin 2A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CORO2A mRNA CTD PMID:28903501 NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of COX5A mRNA CTD PMID:19162173 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of COX8A mRNA CTD PMID:19162173 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Cpb2 carboxypeptidase B2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CPB2 mRNA CTD PMID:28903501 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CPEB2 mRNA CTD PMID:22698814 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743
JBrowse link
G Cpne8 copine 8 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CPNE8 mRNA CTD PMID:28903501 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CPS1 mRNA CTD PMID:19162173 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CPT1B mRNA CTD PMID:19162173 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpxm2 carboxypeptidase X (M14 family), member 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CPXM2 mRNA CTD PMID:22698814 NCBI chr 1:186,836,797...186,947,222
Ensembl chr 1:186,836,797...186,947,220
JBrowse link
G Crcp CGRP receptor component increases expression ISO Pregnenolone Carbonitrile results in increased expression of CRCP mRNA CTD PMID:28903501 NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CREG1 mRNA CTD PMID:19162173 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Crip2 cysteine-rich protein 2 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CRIP2 mRNA
Pregnenolone Carbonitrile results in increased expression of CRIP2 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CROT mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CROT mRNA]
CTD PMID:19162173 PMID:20359477 PMID:28903501 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Crp C-reactive protein increases expression ISO Pregnenolone Carbonitrile results in increased expression of CRP mRNA CTD PMID:28903501 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cryaa crystallin, alpha A increases expression EXP Pregnenolone Carbonitrile results in increased expression of CRYAA mRNA CTD PMID:19162173 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Crybb1 crystallin, beta B1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CRYBB1 mRNA CTD PMID:22698814 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344
JBrowse link
G Crybb3 crystallin, beta B3 decreases expression
increases expression
ISO Pregnenolone Carbonitrile results in decreased expression of CRYBB3 mRNA
Pregnenolone Carbonitrile results in increased expression of CRYBB3 mRNA
CTD PMID:22698814 PMID:28903501 NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120
JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Pregnenolone Carbonitrile results in increased expression of CSF2RB mRNA; Pregnenolone Carbonitrile results in increased expression of CSF2RB2 mRNA CTD PMID:28903501 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CSRNP1 mRNA CTD PMID:28903501 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Cstb cystatin B decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CSTB mRNA CTD PMID:19162173 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CTH mRNA CTD PMID:19162173 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnd2 catenin delta 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CTNND2 mRNA CTD PMID:19162173 NCBI chr 2:81,168,976...82,016,495
Ensembl chr 2:81,167,117...82,015,764
JBrowse link
G Ctps1 CTP synthase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CTPS mRNA CTD PMID:28903501 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Ctsd cathepsin D increases expression EXP Pregnenolone Carbonitrile results in increased expression of CTSD mRNA CTD PMID:19162173 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsl cathepsin L decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CTSL mRNA
Pregnenolone Carbonitrile results in increased expression of CTSL mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Ctss cathepsin S decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CTSS mRNA CTD PMID:19162173 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cuta cutA divalent cation tolerance homolog decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CUTA mRNA CTD PMID:19162173 NCBI chr20:5,022,956...5,024,580
Ensembl chr20:5,022,956...5,024,552
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CXCL1 mRNA CTD PMID:27413110 PMID:28903501 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cyb561 cytochrome b-561 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYB561 mRNA CTD PMID:28903501 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787
JBrowse link
G Cyb5a cytochrome b5 type A affects expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile affects the expression of CYB5A mRNA
Pregnenolone Carbonitrile results in increased expression of CYB5A mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYB5R3 mRNA CTD PMID:19162173 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cyc1 cytochrome c-1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYC1 mRNA CTD PMID:19162173 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cycs cytochrome c, somatic decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYCS mRNA CTD PMID:19162173 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP17A1 mRNA CTD PMID:19162173 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
multiple interactions
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CYP1A1 mRNA
Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]
Pregnenolone Carbonitrile results in increased expression of CYP1A1 mRNA
CTD PMID:19118567 PMID:19162173 PMID:28428138 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
multiple interactions
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CYP1A2 mRNA
NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in decreased expression of CYP1A2 mRNA]
Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]
Pregnenolone Carbonitrile results in increased expression of CYP1A2 mRNA
CTD PMID:15596064 PMID:19162173 PMID:27413110 PMID:28428138 PMID:29548889 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA] CTD PMID:28428138 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP21A1 mRNA CTD PMID:28903501 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP24A1 mRNA CTD PMID:15630458 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP26A1 mRNA CTD PMID:28903501 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP27A1 mRNA CTD PMID:28903501 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2A1 mRNA CTD PMID:15596064 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2A2 mRNA CTD PMID:19162173 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP2A5 mRNA CTD PMID:27413110 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
affects expression
increases expression
ISO
EXP
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP2B10 mRNA; [Pregnenolone Carbonitrile co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA; [Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP2B10 gene]] which results in increased expression of CYP2B10 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA]; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA]; NR1I3 protein promotes the reaction [[Pregnenolone Carbonitrile co-treated with Lithocholic Acid] results in increased expression of CYP2B10 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to CYP2B10 gene]; Pregnenolone Carbonitrile promotes the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA]
Pregnenolone Carbonitrile affects the expression of CYP2B10 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP2B1 mRNA
NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B1 mRNA]
Pregnenolone Carbonitrile results in increased expression of CYP2B10 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP2B10 protein
CTD PMID:15986414 PMID:17627975 PMID:18488193 PMID:19433268 PMID:20359477 More... NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2B15 mRNA CTD PMID:19162173 PMID:19850644 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CYP2B2 mRNA
NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2B2 mRNA]
Pregnenolone Carbonitrile results in increased expression of CYP2B13 mRNA
CTD PMID:15596064 PMID:19162173 PMID:19850644 PMID:27413110 PMID:29548889 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CYP2B3 mRNA
Pregnenolone Carbonitrile results in decreased expression of CYP2B9 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP2B3 mRNA
CTD PMID:15596064 PMID:19162173 PMID:27413110 PMID:28903501 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2C mRNA CTD PMID:19162173 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP2C22 mRNA CTD PMID:19162173 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions
increases expression
ISO NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C55 mRNA]; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP2C55 mRNA] CTD PMID:20371638 PMID:22698814 PMID:27413110 PMID:28903501 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CYP2C38 mRNA CTD PMID:28903501 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO Pregnenolone Carbonitrile results in increased expression of CYP2C29 mRNA CTD PMID:28903501
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP2D3 mRNA CTD PMID:19162173 NCBI chr 7:113,917,711...113,922,068 JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CYP2F4 mRNA
Pregnenolone Carbonitrile results in decreased expression of CYP2F2 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP2F1 mRNA
CTD PMID:15596064 PMID:19162173 PMID:27413110 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP2J3 mRNA CTD PMID:19162173 NCBI chr 5:111,219,921...111,244,987 JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CYP2U1 mRNA CTD PMID:28903501 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP3A18 mRNA CTD PMID:15596064 PMID:19162173 PMID:19850644 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
increases activity
EXP
ISO
[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]; Pregnenolone Carbonitrile results in increased expression of and results in increased activity of CYP3A2 protein
[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; NR1I2 gene promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A4 protein]; NR3C1 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A4 mRNA]
Pregnenolone Carbonitrile results in increased expression of CYP3A4 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP3A4 protein
Pregnenolone Carbonitrile results in increased expression of CYP3A2 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP3A2 protein
Pregnenolone Carbonitrile results in increased activity of CYP3A2 protein
CTD PMID:10219967 PMID:12458634 PMID:12505310 PMID:15541768 PMID:15588932 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions
increases activity
increases expression
EXP [Dietary Fats co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A23-3A1 protein; Clofibrate promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 protein]; diphenyleneiodonium inhibits the reaction [Pregnenolone Carbonitrile results in increased activity of CYP3A23-3A1 protein]; NR1I2 gene mutant form inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 mRNA]; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 mRNA]; perfluorodecanoic acid inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 protein]; Pregnenolone Carbonitrile promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]
Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 mRNA; Pregnenolone Carbonitrile results in increased expression of CYP3A23-3A1 protein
CTD PMID:9817075 PMID:10772642 PMID:11752103 PMID:12370413 PMID:12869653 More... NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of CYP3A9 mRNA
Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA
trichostatin A inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of CYP3A11 mRNA]
Pregnenolone Carbonitrile results in increased expression of CYP3A13 mRNA
CTD PMID:15596064 PMID:19162173 PMID:19562681 PMID:19850644 PMID:20888898 More... NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4A1 mRNA CTD PMID:19162173 PMID:29548889 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4A2 mRNA CTD PMID:19162173 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4A3 mRNA CTD PMID:19162173 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP4B1 mRNA CTD PMID:15596064 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of CYP4F14 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP4F14 mRNA]
CTD PMID:20359477 PMID:28903501 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP4F4 mRNA CTD PMID:15596064 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP Pregnenolone Carbonitrile results in increased expression of CYP4F5 mRNA CTD PMID:19162173 NCBI chr 7:11,544,040...11,558,982
Ensembl chr 7:11,544,082...11,558,978
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of CYP4V3 mRNA CTD PMID:28903501 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP7A1 mRNA]
CTD PMID:15629111 PMID:19162173 PMID:20359477 PMID:22982774 PMID:27413110 More... NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of CYP7B1 mRNA CTD PMID:19162173 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP8B1 mRNA] CTD PMID:20359477 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DAAM1 mRNA CTD PMID:28903501 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DACT2 mRNA CTD PMID:19162173 NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096
JBrowse link
G Dancr differentiation antagonizing non-protein coding RNA increases expression ISO Pregnenolone Carbonitrile results in increased expression of DANCR mRNA CTD PMID:28903501 NCBI chr14:34,126,956...34,127,936 JBrowse link
G Dapk3 death-associated protein kinase 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DAPK3 mRNA CTD PMID:19162173 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Dbndd1 dysbindin domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DBNDD1 mRNA CTD PMID:22698814 NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of DBP mRNA
Pregnenolone Carbonitrile results in increased expression of DBP mRNA
CTD PMID:19162173 PMID:27413110 PMID:28903501 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DCAF11 mRNA CTD PMID:19162173 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
JBrowse link
G Dcdc2 doublecortin domain containing 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DCDC2A mRNA CTD PMID:22698814 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743
JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DCUN1D4 mRNA CTD PMID:28903501 NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DDAH1 mRNA CTD PMID:28903501 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DDC mRNA CTD PMID:28903501 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DDIT4 mRNA CTD PMID:28903501 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx21 DExD-box helicase 21 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DDX21 mRNA CTD PMID:28903501 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Ddx27 DEAD-box helicase 27 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DDX27 mRNA CTD PMID:28903501 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
JBrowse link
G Dennd2b DENN domain containing 2B increases expression ISO Pregnenolone Carbonitrile results in increased expression of DENN2B mRNA CTD PMID:28903501 NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680
JBrowse link
G Depdc7 DEP domain containing 7 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DEPDC7 mRNA CTD PMID:28903501 NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124
JBrowse link
G Derl3 derlin 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DERL3 mRNA CTD PMID:28903501 NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
JBrowse link
G Desi2 desumoylating isopeptidase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DESI2 mRNA CTD PMID:28903501 NCBI chr13:89,961,767...90,011,255
Ensembl chr13:89,961,934...90,016,416
JBrowse link
G Dexi Dexi homolog decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DEXI mRNA CTD PMID:28903501 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
JBrowse link
G Dgkg diacylglycerol kinase, gamma increases expression EXP Pregnenolone Carbonitrile results in increased expression of DGKG mRNA CTD PMID:19162173 NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212
JBrowse link
G Dgkz diacylglycerol kinase zeta decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DGKZ mRNA CTD PMID:19162173 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Dhdh dihydrodiol dehydrogenase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DHDH mRNA CTD PMID:28903501 NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197
JBrowse link
G Dhrs1 dehydrogenase/reductase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DHRS1 mRNA CTD PMID:28903501 NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838
JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DHX36 mRNA CTD PMID:19162173 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DIO1 mRNA CTD PMID:19162173 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dis3 DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease increases expression ISO Pregnenolone Carbonitrile results in increased expression of DIS3 mRNA CTD PMID:28903501 NCBI chr15:75,820,040...75,850,450
Ensembl chr15:75,823,436...75,850,642
JBrowse link
G Dis3l2 DIS3-like 3'-5' exoribonuclease 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DIS3L2 mRNA CTD PMID:19162173 NCBI chr 9:87,355,409...87,736,616
Ensembl chr 9:87,356,457...87,736,616
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of DLAT mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DLC1 mRNA CTD PMID:28903501 NCBI chr16:55,246,716...55,671,441
Ensembl chr16:55,291,584...55,671,439
JBrowse link
G Dll1 delta like canonical Notch ligand 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DLL1 mRNA CTD PMID:28903501 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression ISO Pregnenolone Carbonitrile results in increased expression of DLST mRNA CTD PMID:28903501 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like increases expression EXP Pregnenolone Carbonitrile results in increased expression of DMAC2L mRNA CTD PMID:19162173 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DNAJA3 mRNA CTD PMID:28903501 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DNAJB9 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnm3 dynamin 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DNM3 mRNA CTD PMID:19162173 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108
JBrowse link
G Dop1a DOP1 leucine zipper like protein A increases expression ISO Pregnenolone Carbonitrile results in increased expression of DOP1A mRNA CTD PMID:28903501 NCBI chr 8:87,415,266...87,517,935
Ensembl chr 8:87,414,593...87,518,353
JBrowse link
G Dop1b DOP1 leucine zipper like protein B increases expression ISO Pregnenolone Carbonitrile results in increased expression of DOP1B mRNA CTD PMID:28903501 NCBI chr11:33,024,376...33,125,931
Ensembl chr11:33,024,411...33,125,931
JBrowse link
G Dpp9 dipeptidyl peptidase 9 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DPP9 mRNA CTD PMID:28903501 NCBI chr 9:1,011,347...1,046,337
Ensembl chr 9:1,011,351...1,046,541
JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DRG1 mRNA CTD PMID:28903501 NCBI chr14:78,103,876...78,119,976
Ensembl chr14:78,103,876...78,119,953
JBrowse link
G Dsc2 desmocollin 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DSC2 mRNA CTD PMID:28903501 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Dsg2 desmoglein 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DSG2 mRNA CTD PMID:28903501 NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Dsp desmoplakin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DSP mRNA CTD PMID:28903501 NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of DTX4 mRNA CTD PMID:28903501 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DUSP1 mRNA CTD PMID:19162173 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp6 dual specificity phosphatase 6 affects expression EXP Pregnenolone Carbonitrile affects the expression of DUSP6 mRNA CTD PMID:19162173 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
JBrowse link
G Dxo decapping exoribonuclease increases expression ISO Pregnenolone Carbonitrile results in increased expression of DXO mRNA CTD PMID:28903501 NCBI chr20:3,993,322...3,995,484
Ensembl chr20:3,993,327...3,995,494
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of DYNC1H1 mRNA CTD PMID:19162173 NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of DYNC2H1 mRNA CTD PMID:19162173 NCBI chr 8:4,189,257...4,412,183
Ensembl chr 8:4,189,257...4,412,183
JBrowse link
G Dynll2 dynein light chain LC8-type 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of DYNLL2 mRNA CTD PMID:28903501 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of E2F1 mRNA CTD PMID:23626729 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of E2F2 mRNA CTD PMID:28903501 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EBNA1BP2 mRNA CTD PMID:28903501 NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ECH1 mRNA CTD PMID:19162173 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Echdc3 enoyl CoA hydratase domain containing 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ECHDC3 mRNA CTD PMID:28903501 NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ECHS1 mRNA CTD PMID:19162173 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EEF1B2 mRNA CTD PMID:28903501 NCBI chr 9:64,580,009...64,582,737
Ensembl chr 9:64,579,893...64,582,737
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EEF2K mRNA CTD PMID:28903501 NCBI chr 1:175,393,119...175,454,452
Ensembl chr 1:175,393,154...175,455,164
JBrowse link
G Efna3 ephrin A3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EFNA3 mRNA CTD PMID:28903501 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Egfl7 EGF-like-domain, multiple 7 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of EGFL7 mRNA CTD PMID:19162173 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
JBrowse link
G Egr1 early growth response 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of EGR1 mRNA CTD PMID:19162173 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EGR2 mRNA CTD PMID:22698814 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of EHHADH mRNA CTD PMID:19162173 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H increases expression ISO Pregnenolone Carbonitrile results in increased expression of EIF3H mRNA CTD PMID:28903501 NCBI chr 7:83,091,045...83,174,436
Ensembl chr 7:83,091,039...83,174,451
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EIF4A1 mRNA CTD PMID:28903501 NCBI chr10:54,384,345...54,389,853
Ensembl chr10:54,384,347...54,389,858
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of EIF4A2 mRNA CTD PMID:19162173 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EIF4EBP3 mRNA CTD PMID:28903501 NCBI chr18:28,263,089...28,268,033 JBrowse link
G Elfn1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ELFN1 mRNA CTD PMID:22698814 NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ELOVL3 mRNA CTD PMID:28903501 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ELOVL5 mRNA CTD PMID:28903501 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ELOVL6 mRNA CTD PMID:28903501 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ELOVL7 mRNA CTD PMID:22698814 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845
JBrowse link
G Emb embigin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EMB mRNA CTD PMID:22698814 NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050
JBrowse link
G Emilin2 elastin microfibril interfacer 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EMILIN2 mRNA CTD PMID:22698814 NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352
JBrowse link
G Enho energy homeostasis associated decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ENHO mRNA CTD PMID:28903501 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777
JBrowse link
G Enpp6 ectonucleotide pyrophosphatase/phosphodiesterase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ENPP6 mRNA CTD PMID:28903501 NCBI chr16:45,165,883...45,294,126
Ensembl chr16:45,169,178...45,294,077
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ENTPD2 mRNA CTD PMID:19162173 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EPAS1 mRNA CTD PMID:28903501 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of EPB41 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821
JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP Pregnenolone Carbonitrile results in increased expression of EPCAM mRNA CTD PMID:19162173 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Epha1 Eph receptor A1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EPHA1 mRNA CTD PMID:28903501 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA
[Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA
CTD PMID:19162173 PMID:20359477 PMID:27413110 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EPHX2 mRNA CTD PMID:27413110 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Eppk1 epiplakin 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EPPK1 mRNA CTD PMID:28903501 NCBI chr 7:107,816,919...107,842,946 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ERN1 mRNA CTD PMID:19162173 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ERO1B mRNA CTD PMID:28903501 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP Pregnenolone Carbonitrile results in increased expression of ERP29 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ERRFI1 mRNA CTD PMID:28903501 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esam endothelial cell adhesion molecule increases expression ISO Pregnenolone Carbonitrile results in increased expression of ESAM mRNA CTD PMID:28903501 NCBI chr 8:37,238,228...37,249,217
Ensembl chr 8:37,238,287...37,249,215
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ESCO2 mRNA CTD PMID:22698814 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Esrra estrogen related receptor, alpha increases expression EXP Pregnenolone Carbonitrile results in increased expression of ESRRA mRNA CTD PMID:19162173 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Etl4 enhancer trap locus 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ETL4 mRNA CTD PMID:28903501 NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715
JBrowse link
G Etnk2 ethanolamine kinase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of ETNK2 mRNA CTD PMID:28903501 NCBI chr13:44,811,224...44,829,037
Ensembl chr13:44,811,015...44,829,037
JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of ETNPPL mRNA CTD PMID:27413110 NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212
JBrowse link
G Exo1 exonuclease 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXO1 mRNA CTD PMID:22698814 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Exosc1 exosome component 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXOSC1 mRNA CTD PMID:28903501 NCBI chr 1:240,734,777...240,745,518
Ensembl chr 1:240,734,773...240,745,438
JBrowse link
G Exosc2 exosome component 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXOSC2 mRNA CTD PMID:28903501 NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575
JBrowse link
G Exosc8 exosome component 8 increases expression ISO Pregnenolone Carbonitrile results in increased expression of EXOSC8 mRNA CTD PMID:28903501 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Exph5 exophilin 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of EXPH5 mRNA CTD PMID:28903501 NCBI chr 8:53,698,825...53,775,371
Ensembl chr 8:53,698,852...53,773,169
JBrowse link
G F10 coagulation factor X decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of F10 mRNA CTD PMID:19162173 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G Faah fatty acid amide hydrolase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAAH mRNA CTD PMID:28903501 NCBI chr 5:129,479,774...129,499,018 JBrowse link
G Faahl fatty-acid amide hydrolase-like decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAAH mRNA CTD PMID:28903501
G Fabp1 fatty acid binding protein 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FABP1 mRNA CTD PMID:28903501 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of FABP2 mRNA CTD PMID:19162173 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of FABP5 mRNA
Pregnenolone Carbonitrile results in increased expression of FABP5 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FADS2 mRNA CTD PMID:28903501 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fads3 fatty acid desaturase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FADS3 mRNA CTD PMID:28903501 NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769
JBrowse link
G Fads6 fatty acid desaturase 6 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FADS6 mRNA CTD PMID:20359477 NCBI chr10:100,522,981...100,538,181
Ensembl chr10:100,522,981...100,538,181
JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAHD1 mRNA CTD PMID:28903501 NCBI chr10:13,873,539...13,874,978
Ensembl chr10:13,873,527...13,875,012
JBrowse link
G Fam102a family with sequence similarity 102, member A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM102A mRNA CTD PMID:28903501 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643
JBrowse link
G Fam149a family with sequence similarity 149, member A decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM149A mRNA CTD PMID:28903501 NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066
JBrowse link
G Fam189a2 family with sequence similarity 189, member A2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM189A2 mRNA CTD PMID:22698814 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM20C mRNA CTD PMID:28903501 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FAM78B mRNA CTD PMID:22698814 NCBI chr13:79,162,405...79,250,958 JBrowse link
G Fanca FA complementation group A increases expression ISO Pregnenolone Carbonitrile results in increased expression of FANCA mRNA CTD PMID:22698814 NCBI chr19:51,304,021...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Fancg FA complementation group G increases expression ISO Pregnenolone Carbonitrile results in increased expression of FANCG mRNA CTD PMID:22698814 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
JBrowse link
G Fanci FA complementation group I increases expression ISO Pregnenolone Carbonitrile results in increased expression of FANCI mRNA CTD PMID:22698814 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FARP1 mRNA CTD PMID:28903501 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of FAS mRNA CTD PMID:19162173 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase decreases expression
multiple interactions
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of FASN mRNA
Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of FASN mRNA]
Pregnenolone Carbonitrile results in increased expression of FASN mRNA
CTD PMID:19162173 PMID:20359477 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbf1 Fas binding factor 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FBF1 mRNA CTD PMID:28903501 NCBI chr10:101,375,769...101,401,624
Ensembl chr10:101,375,775...101,401,644
JBrowse link
G Fbxo21 F-box protein 21 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FBXO21 mRNA CTD PMID:28903501 NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133
JBrowse link
G Fbxo31 F-box protein 31 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FBXO31 mRNA CTD PMID:28903501 NCBI chr19:49,624,818...49,656,083
Ensembl chr19:49,627,686...49,656,010
JBrowse link
G Fbxo44 F-box protein 44 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FBXO44 mRNA CTD PMID:22698814 NCBI chr 5:158,583,363...158,592,510
Ensembl chr 5:158,583,366...158,592,363
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of FCGR2A mRNA CTD PMID:19162173 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FDFT1 mRNA CTD PMID:28903501 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FDPS mRNA CTD PMID:28903501 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdx1 ferredoxin 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FDX1 mRNA CTD PMID:28903501 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414
JBrowse link
G Fga fibrinogen alpha chain decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of FGA mRNA
Pregnenolone Carbonitrile results in increased expression of FGA mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain increases expression ISO Pregnenolone Carbonitrile results in increased expression of FGB mRNA CTD PMID:28903501 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of FGF1 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf21 fibroblast growth factor 21 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FGF21 mRNA CTD PMID:22698814 PMID:28903501 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FGFR4 mRNA CTD PMID:28903501 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FGFRL1 mRNA CTD PMID:28903501 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Pregnenolone Carbonitrile results in increased expression of FGG mRNA CTD PMID:28903501 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FGL1 mRNA CTD PMID:28903501 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Fh fumarate hydratase increases expression ISO Pregnenolone Carbonitrile results in increased expression of FH1 mRNA CTD PMID:28903501 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fign fidgetin, microtubule severing factor decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FIGN mRNA CTD PMID:28903501 NCBI chr 3:48,637,510...48,760,772
Ensembl chr 3:48,642,496...48,760,787
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression EXP Pregnenolone Carbonitrile results in increased expression of FKBP11 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
JBrowse link
G Fkbp14 FKBP prolyl isomerase 14 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FKBP14 mRNA CTD PMID:28903501 NCBI chr 4:83,705,531...83,721,515
Ensembl chr 4:83,705,652...83,721,528
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 affects expression
increases expression
EXP Pregnenolone Carbonitrile affects the expression of FKBP4 mRNA
Pregnenolone Carbonitrile results in increased expression of FKBP4 mRNA
CTD PMID:19162173 PMID:21318169 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FKBP5 mRNA CTD PMID:28903501 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flcn folliculin increases expression ISO Pregnenolone Carbonitrile results in increased expression of FLCN mRNA CTD PMID:28903501 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Flot2 flotillin 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FLOT2 mRNA CTD PMID:28903501 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of FMO1 mRNA CTD PMID:19162173 PMID:27413110 PMID:28903501 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FMO4 mRNA CTD PMID:28903501 NCBI chr13:75,154,683...75,172,932
Ensembl chr13:75,154,684...75,172,874
JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of FN1 mRNA
Pregnenolone Carbonitrile results in increased expression of FN1 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fn3k fructosamine 3 kinase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FN3K mRNA CTD PMID:28903501 NCBI chr10:106,700,302...106,715,903
Ensembl chr10:106,700,670...106,715,895
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of FOS mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of FOS mRNA]
CTD PMID:22698814 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Pregnenolone Carbonitrile results in increased expression of FOSL2 mRNA CTD PMID:28903501 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
JBrowse link
G Foxk2 forkhead box K2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of FOXK2 mRNA CTD PMID:19162173 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563
JBrowse link
G Foxm1 forkhead box M1 increases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in increased expression of FOXM1 mRNA
[Pregnenolone Carbonitrile co-treated with Phenobarbital] results in increased expression of FOXM1 mRNA; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of FOXM1 mRNA]
CTD PMID:22698814 PMID:33398415 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo1 forkhead box O1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FOXO1 mRNA CTD PMID:28903501 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Fst follistatin decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FST mRNA CTD PMID:28903501 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
JBrowse link
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of FTSJ3 mRNA CTD PMID:28903501 NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,180,696...91,187,397
JBrowse link
G Fuom fucose mutarotase increases expression ISO Pregnenolone Carbonitrile results in increased expression of FUOM mRNA CTD PMID:28903501 NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FXYD5 mRNA CTD PMID:22698814 NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
JBrowse link
G Fzd3 frizzled class receptor 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of FZD3 mRNA CTD PMID:22698814 NCBI chr15:39,421,366...39,488,369
Ensembl chr15:39,421,355...39,488,369
JBrowse link
G G0s2 G0/G1switch 2 increases expression
decreases expression
ISO Pregnenolone Carbonitrile results in increased expression of G0S2 mRNA
Pregnenolone Carbonitrile results in decreased expression of G0S2 mRNA
CTD PMID:27413110 PMID:28903501 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP Pregnenolone Carbonitrile affects the expression of G6PC1 mRNA CTD PMID:19162173 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gaa alpha glucosidase increases expression EXP Pregnenolone Carbonitrile results in increased expression of GAA mRNA CTD PMID:19162173 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of GADD45A mRNA
[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Pregnenolone Carbonitrile] results in increased expression of GADD45A mRNA
CTD PMID:19162173 PMID:23626729 PMID:28903501 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Pregnenolone Carbonitrile results in increased expression of GADD45B mRNA CTD PMID:27413110 PMID:28903501 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Pregnenolone Carbonitrile results in increased expression of GADD45G mRNA CTD PMID:28903501 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GALE mRNA CTD PMID:28903501 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GALNT2 mRNA CTD PMID:28903501 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GAMT mRNA CTD PMID:28903501 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gar1 GAR1 ribonucleoprotein increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAR1 mRNA CTD PMID:28903501 NCBI chr 2:218,375,231...218,382,509
Ensembl chr 2:218,375,353...218,382,524
JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAS2L1 mRNA CTD PMID:22698814 NCBI chr14:79,951,702...79,961,830
Ensembl chr14:79,950,555...79,961,438
JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAS2L3 mRNA CTD PMID:22698814 NCBI chr 7:23,803,578...23,836,816 JBrowse link
G Gas5 growth arrest specific 5 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GAS5 mRNA CTD PMID:19162173 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gas6 growth arrest specific 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GAS6 mRNA CTD PMID:19162173 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GAS7 mRNA CTD PMID:22698814 NCBI chr10:52,152,728...52,383,276
Ensembl chr10:52,152,493...52,383,276
JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GCC2 mRNA CTD PMID:22698814 NCBI chr20:26,247,394...26,293,613
Ensembl chr20:26,247,404...26,293,613
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GCH1 mRNA CTD PMID:19162173 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gck glucokinase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GCK protein CTD PMID:26616219 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
decreases expression
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of GCLC mRNA
Pregnenolone Carbonitrile results in decreased expression of GCLC mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP Pregnenolone Carbonitrile results in increased expression of GCLM mRNA CTD PMID:19162173 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gda guanine deaminase increases expression EXP Pregnenolone Carbonitrile results in increased expression of GDA mRNA CTD PMID:19162173 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GDE1 mRNA CTD PMID:19162173 NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429
JBrowse link
G Gfra1 GDNF family receptor alpha 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GFRA1 mRNA CTD PMID:28903501 NCBI chr 1:257,315,682...257,552,004 JBrowse link
G Ggact gamma-glutamylamine cyclotransferase decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GGACT mRNA CTD PMID:28903501 NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GGT1 mRNA CTD PMID:19162173 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ghr growth hormone receptor decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of GHR mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
JBrowse link
G Ghsr growth hormone secretagogue receptor increases expression EXP Pregnenolone Carbonitrile results in increased expression of GHSR mRNA CTD PMID:19162173 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gin1 gypsy retrotransposon integrase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GIN1 mRNA CTD PMID:28903501 NCBI chr 9:98,293,596...98,315,155
Ensembl chr 9:98,293,597...98,315,848
JBrowse link
G Gins2 GINS complex subunit 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GINS2 mRNA CTD PMID:22698814 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GJA1 mRNA CTD PMID:28903501 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja4 gap junction protein, alpha 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GJA4 mRNA CTD PMID:28903501 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
JBrowse link
G Gjb4 gap junction protein, beta 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GJB4 mRNA CTD PMID:28903501 NCBI chr 5:139,675,776...139,679,551
Ensembl chr 5:139,675,780...139,679,667
JBrowse link
G Glipr2 GLI pathogenesis-related 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GLIPR2 mRNA CTD PMID:22698814 NCBI chr 5:58,170,417...58,200,947
Ensembl chr 5:58,170,425...58,202,272
JBrowse link
G Gls2 glutaminase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GLS2 mRNA CTD PMID:19162173 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Glt1d1 glycosyltransferase 1 domain containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GLT1D1 mRNA CTD PMID:28903501 NCBI chr12:28,975,984...29,049,707
Ensembl chr12:28,975,988...29,049,695
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GLUD1 mRNA CTD PMID:19162173 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GLUL mRNA CTD PMID:19162173 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gmfb glia maturation factor, beta increases expression EXP Pregnenolone Carbonitrile results in increased expression of GMFB mRNA CTD PMID:19162173 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
JBrowse link
G Gnao1 G protein subunit alpha o1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GNAO1 mRNA CTD PMID:19162173 NCBI chr19:11,034,874...11,192,502
Ensembl chr19:11,035,956...11,192,493
JBrowse link
G Gnas GNAS complex locus increases expression ISO Pregnenolone Carbonitrile results in increased expression of GNAS mRNA CTD PMID:22698814 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gnb5 G protein subunit beta 5 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GNB5 mRNA CTD PMID:19162173 NCBI chr 8:76,076,227...76,104,151
Ensembl chr 8:76,073,306...76,105,069
JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GNE mRNA CTD PMID:19162173 NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499
JBrowse link
G Gnl2 G protein nucleolar 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GNL2 mRNA CTD PMID:28903501 NCBI chr 5:137,293,141...137,318,528
Ensembl chr 5:137,293,081...137,318,526
JBrowse link
G Gnl3 G protein nucleolar 3 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GNL3 mRNA CTD PMID:28903501 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of GNMT mRNA
Pregnenolone Carbonitrile results in increased expression of GNMT mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GNPDA1 mRNA CTD PMID:28903501 NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486
JBrowse link
G Golph3l golgi phosphoprotein 3-like increases expression ISO Pregnenolone Carbonitrile results in increased expression of GOLPH3L mRNA CTD PMID:22698814 NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083
JBrowse link
G Gorasp1 golgi reassembly stacking protein 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GORASP1 mRNA CTD PMID:28903501 NCBI chr 8:119,655,267...119,667,022
Ensembl chr 8:119,655,268...119,666,972
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GOSR2 mRNA CTD PMID:19162173 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression
increases expression
EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of GOT1 mRNA
Pregnenolone Carbonitrile results in increased expression of GOT1 mRNA
CTD PMID:19162173 PMID:28903501 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GPAM mRNA CTD PMID:28903501 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpatch4 G patch domain containing 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPATCH4 mRNA CTD PMID:28903501 NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684
JBrowse link
G Gpc4 glypican 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPC4 mRNA CTD PMID:28903501 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPCPD1 mRNA CTD PMID:28903501 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GPD1 mRNA CTD PMID:28903501 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GPD2 mRNA CTD PMID:19162173 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPT2 mRNA CTD PMID:27413110 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GPX1 mRNA CTD PMID:19162173 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GPX2 mRNA CTD PMID:19162173 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GPX7 mRNA CTD PMID:22698814 NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GRB2 mRNA CTD PMID:28903501 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grb7 growth factor receptor bound protein 7 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GRB7 mRNA CTD PMID:28903501 NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A increases expression EXP Pregnenolone Carbonitrile results in increased expression of GRIN3A mRNA CTD PMID:19162173 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GRK5 mRNA CTD PMID:19162173 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Grn granulin precursor increases expression ISO Pregnenolone Carbonitrile results in increased expression of GRN mRNA CTD PMID:28903501 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Grpel2 GrpE-like 2, mitochondrial decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of GRPEL2 mRNA CTD PMID:28903501 NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180
JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GRWD1 mRNA CTD PMID:28903501 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
JBrowse link
G Gsap gamma-secretase activating protein increases expression ISO Pregnenolone Carbonitrile results in increased expression of GSAP mRNA CTD PMID:28903501 NCBI chr 4:13,813,046...13,907,875
Ensembl chr 4:13,813,046...13,907,814
JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP
ISO
Pregnenolone Carbonitrile results in increased expression of GSR mRNA CTD PMID:19162173 PMID:27413110 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression
ISO NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA2 mRNA] CTD PMID:22698814 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GSTA3 mRNA CTD PMID:19162173 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GSTA4 mRNA CTD PMID:19162173 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in increased expression of GSTA1 mRNA
[Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTA1 gene]] which results in increased expression of GSTA1 mRNA; [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTA1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTA1 gene]
CTD PMID:20693526 PMID:22496397 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 multiple interactions
increases expression
ISO NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of GSTA2 mRNA] CTD PMID:22698814 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression
ISO
EXP
[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM1 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM1 5' UTR] CTD PMID:18723825 PMID:19162173 PMID:20693526 PMID:22496397 PMID:27413110 More... NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
multiple interactions
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of GSTM2 mRNA
[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM2 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM2 mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM2 gene]
CTD PMID:18723825 PMID:19162173 PMID:20693526 PMID:22496397 PMID:27413110 More... NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression EXP Pregnenolone Carbonitrile results in increased expression of GSTM5 mRNA CTD PMID:19162173 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression ISO Pregnenolone Carbonitrile results in increased expression of GSTM4 mRNA CTD PMID:22496397 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
decreases expression
increases expression
ISO [Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM3 mRNA; NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM3 mRNA]
Pregnenolone Carbonitrile results in decreased expression of GSTM5 mRNA
CTD PMID:18723825 PMID:22496397 PMID:27413110 PMID:28903501 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 multiple interactions
decreases expression
ISO [Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of GSTT2 mRNA
Pregnenolone Carbonitrile results in decreased expression of GSTT2 mRNA
CTD PMID:22496397 PMID:28903501 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GTF2IRD1 mRNA CTD PMID:19162173 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
JBrowse link
G Gyg1 glycogenin 1 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of GYG1 mRNA CTD PMID:19162173 NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
JBrowse link
G Gys2 glycogen synthase 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of GYS2 mRNA CTD PMID:19162173 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228
JBrowse link
G H1f0 H1.0 linker histone decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of H1F0 mRNA CTD PMID:19162173 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H1f10 H1.10 linker histone increases expression ISO Pregnenolone Carbonitrile results in increased expression of H1F10 mRNA CTD PMID:22698814 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448
JBrowse link
G H2az1 H2A.Z variant histone 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of H2AZ1 mRNA CTD PMID:19162173 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G H3f3b H3.3 histone B increases expression ISO Pregnenolone Carbonitrile results in increased expression of H3F3B mRNA CTD PMID:28903501 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hal histidine ammonia lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HAL mRNA CTD PMID:19162173 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP
ISO
Pregnenolone Carbonitrile results in decreased expression of HAO2 mRNA CTD PMID:19162173 PMID:28903501 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Pregnenolone Carbonitrile results in increased expression of HASPIN mRNA CTD PMID:22698814 NCBI chr10:57,747,731...57,750,532
Ensembl chr10:57,747,573...57,750,512
JBrowse link
G Hdc histidine decarboxylase increases expression EXP Pregnenolone Carbonitrile results in increased expression of HDC mRNA CTD PMID:19162173 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Heatr1 HEAT repeat containing 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HEATR1 mRNA CTD PMID:28903501 NCBI chr17:58,051,700...58,093,895
Ensembl chr17:58,051,700...58,093,948
JBrowse link
G Hectd2 HECT domain E3 ubiquitin protein ligase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HECTD2 mRNA CTD PMID:28903501 NCBI chr 1:234,274,967...234,345,598
Ensembl chr 1:234,275,705...234,343,487
JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HERC2 mRNA CTD PMID:22698814 NCBI chr 1:106,904,789...107,110,997
Ensembl chr 1:106,880,084...107,108,134
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HERPUD1 mRNA CTD PMID:28903501 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HES1 mRNA CTD PMID:19162173 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HES6 mRNA CTD PMID:28903501 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hfe homeostatic iron regulator increases expression EXP Pregnenolone Carbonitrile results in increased expression of HFE mRNA CTD PMID:19162173 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hgf hepatocyte growth factor decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HGF mRNA CTD PMID:19162173 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hgfac HGF activator decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HGFAC mRNA CTD PMID:28903501 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HHEX mRNA CTD PMID:28903501 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha increases expression ISO Pregnenolone Carbonitrile results in increased expression of HIF3A mRNA CTD PMID:28903501 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HIGD1A mRNA CTD PMID:19162173 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of H2BC21 mRNA CTD PMID:28903501 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Hmg20b high mobility group 20 B increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMG20B mRNA CTD PMID:19162173 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMGA2 mRNA CTD PMID:19162173 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmgb2 high mobility group box 2 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMGB2 mRNA CTD PMID:19162173 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HMGCL mRNA CTD PMID:19162173 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
ISO [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of HMGCR mRNA; NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in increased expression of HMGCR mRNA] CTD PMID:20359477 PMID:22698814 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions
decreases expression
ISO Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of HMGCS2 mRNA]
Pregnenolone Carbonitrile results in decreased expression of HMGCS2 mRNA
CTD PMID:20359477 PMID:28903501 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMMR mRNA CTD PMID:19162173 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HMOX1 mRNA CTD PMID:19162173 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hmox2 heme oxygenase 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HMOX2 mRNA CTD PMID:28903501 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hnf1a HNF1 homeobox A decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HNF1A mRNA CTD PMID:20888898 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression
multiple interactions
decreases expression
EXP
ISO
Pregnenolone Carbonitrile results in increased expression of HNF4A mRNA
[Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in decreased expression of HNF4A mRNA
Pregnenolone Carbonitrile results in decreased expression of HNF4A mRNA
CTD PMID:19162173 PMID:20359477 PMID:20888898 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C increases expression EXP Pregnenolone Carbonitrile results in increased expression of HNRNPC mRNA CTD PMID:19162173 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HOMER1 mRNA CTD PMID:19162173 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Hoxa2 homeobox A2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of HOXA2 mRNA CTD PMID:22698814
G Hp haptoglobin increases expression ISO Pregnenolone Carbonitrile results in increased expression of HP mRNA CTD PMID:28903501 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hpx hemopexin increases expression ISO Pregnenolone Carbonitrile results in increased expression of HPX mRNA CTD PMID:28903501 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression EXP Pregnenolone Carbonitrile results in increased expression of HRK mRNA CTD PMID:19162173 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSD11B1 mRNA CTD PMID:19162173 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD17B11 mRNA CTD PMID:27413110 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD17B13 mRNA CTD PMID:28903501 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HSD17B2 mRNA CTD PMID:19162173 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HSD17B6 mRNA CTD PMID:19162173 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD3B2 mRNA CTD PMID:28903501 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSD3B3 mRNA CTD PMID:28903501 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
JBrowse link
G Hsf4 heat shock transcription factor 4 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of HSF4 mRNA CTD PMID:28903501 NCBI chr19:33,147,755...33,153,479
Ensembl chr19:33,147,755...33,153,479
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSP90AA1 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression
multiple interactions
ISO Pregnenolone Carbonitrile results in decreased expression of HSPA1B mRNA
NR1I2 protein promotes the reaction [Pregnenolone Carbonitrile results in decreased expression of HSPA1B mRNA]
CTD PMID:22698814 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSPA8 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb6 heat shock protein family B (small) member 6 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of HSPB6 mRNA CTD PMID:19162173 NCBI chr 1:85,806,898...85,809,072
Ensembl chr 1:85,806,146...85,809,071
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSPD1 mRNA CTD PMID:19162173 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HSPH1 mRNA CTD PMID:19162173 PMID:21318169 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HTR4 mRNA CTD PMID:19162173 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321
JBrowse link
G Htt huntingtin increases expression EXP Pregnenolone Carbonitrile results in increased expression of HTT mRNA CTD PMID:19162173 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression EXP Pregnenolone Carbonitrile results in increased expression of HYOU1 mRNA CTD PMID:19162173 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ID1 mRNA CTD PMID:19162173 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G Id2 inhibitor of DNA binding 2 decreases expression EXP Pregnenolone Carbonitrile results in decreased expression of ID2 mRNA CTD PMID:19162173 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of IDH2 mRNA CTD PMID:28903501 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Pregnenolone Carbonitrile results in decreased expression of IER3 mRNA CTD PMID:22698814 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 increases expression ISO Pregnenolone Carbonitrile results in increased expression of IFITM2 mRNA CTD PMID:28903501 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741
JBrowse link
G Ifitm5 interferon induced transmembrane protein 5 increases expression ISO Pregnenolone Carbonitrile results in increased expression of IFITM5 mRNA CTD PMID:28903501 NCBI chr 1:196,045,836...196,052,554
Ensembl chr 1:196,045,666...196,047,232
JBrowse link
G