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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-hydroxy-4-aminobiphenyl
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Accession:CHEBI:16580 term browser browse the term
Definition:A N-substituted amine that is 4-aminobiphenyl substituted by a hydroxy group at the nitrogen atom.
Synonyms:exact_synonym: N-hydroxy-[1,1'-biphenyl]-4-amine
 related_synonym: 4-biphenylhydroxylamine;   4-hydroxyaminobiphenyl;   4-hydroxylaminobiphenyl;   Formula=C12H11NO;   InChI=1S/C12H11NO/c14-13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14H;   InChIKey=MYVLYOJYVMLSFA-UHFFFAOYSA-N;   N-1,1'-biphenyl-4-ylhydroxylamine;   N-4-biphenylylhydroxylamine;   SMILES=C1(C2=CC=CC=C2)=CC=C(C=C1)NO
 alt_id: CHEBI:12601;   CHEBI:21736;   CHEBI:7296
 xref: CAS:6810-26-0;   KEGG:C03622
 xref_mesh: MESH:C014593
 xref: PMID:1600616;   PMID:16970317;   PMID:24881456;   PMID:647655;   Reaxys:2639597


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N-hydroxy-4-aminobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of HRAS gene CTD PMID:11275476 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Nat2 N-acetyltransferase 2 increases metabolic processing ISO NAT2 protein results in increased metabolism of N-hydroxy-4-aminobiphenyl CTD PMID:16857729 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases sulfation		 ISO N-hydroxy-4-aminobiphenyl inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]
SULT1A1 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl		 CTD PMID:17433394 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases sulfation ISO SULT1C2 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl CTD PMID:17433394 NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of TP53 gene CTD PMID:11275476 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
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  CHEBI ontology 19932
    role 19904
      biological role 19902
        aetiopathogenetic role 19263
          carcinogenic agent 18561
            N-hydroxy-4-aminobiphenyl 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    main group molecular entity 19876
                      s-block molecular entity 19705
                        hydrogen molecular entity 19686
                          hydrides 19179
                            inorganic hydride 18191
                              pnictogen hydride 18181
                                nitrogen hydride 18092
                                  azane 17895
                                    ammonia 17894
                                      organic amino compound 17894
                                        primary amino compound 9330
                                          primary amine 6333
                                            primary arylamine 3653
                                              aminobiphenyl 82
                                                biphenyl-4-amine 82
                                                  N-hydroxy-4-aminobiphenyl 5
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