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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-hydroxy-4-aminobiphenyl
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Accession:CHEBI:16580 term browser browse the term
Definition:A N-substituted amine that is 4-aminobiphenyl substituted by a hydroxy group at the nitrogen atom.
Synonyms:exact_synonym: N-hydroxy-[1,1'-biphenyl]-4-amine
 related_synonym: 4-biphenylhydroxylamine;   4-hydroxyaminobiphenyl;   4-hydroxylaminobiphenyl;   Formula=C12H11NO;   InChI=1S/C12H11NO/c14-13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14H;   InChIKey=MYVLYOJYVMLSFA-UHFFFAOYSA-N;   N-1,1'-biphenyl-4-ylhydroxylamine;   N-4-biphenylylhydroxylamine;   SMILES=C1(C2=CC=CC=C2)=CC=C(C=C1)NO
 alt_id: CHEBI:12601;   CHEBI:21736;   CHEBI:7296
 xref: CAS:6810-26-0;   KEGG:C03622
 xref_mesh: MESH:C014593
 xref: PMID:1600616;   PMID:16970317;   PMID:24881456;   PMID:647655;   Reaxys:2639597


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N-hydroxy-4-aminobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of HRAS gene CTD PMID:11275476 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Nat2 N-acetyltransferase 2 increases metabolic processing ISO NAT2 protein results in increased metabolism of N-hydroxy-4-aminobiphenyl CTD PMID:16857729 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases sulfation
ISO N-hydroxy-4-aminobiphenyl inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]
SULT1A1 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl
CTD PMID:17433394 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases sulfation ISO SULT1C2 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl CTD PMID:17433394 NCBI chr 9:4,152,588...4,168,355
Ensembl chr 9:4,152,589...4,168,221
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of TP53 gene CTD PMID:11275476 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

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  CHEBI ontology 19761
    role 19711
      biological role 19711
        aetiopathogenetic role 18963
          carcinogenic agent 18331
            N-hydroxy-4-aminobiphenyl 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19761
    subatomic particle 19759
      composite particle 19759
        hadron 19759
          baryon 19759
            nucleon 19759
              atomic nucleus 19759
                atom 19759
                  main group element atom 19653
                    main group molecular entity 19653
                      s-block molecular entity 19418
                        hydrogen molecular entity 19411
                          hydrides 18751
                            inorganic hydride 17451
                              pnictogen hydride 17426
                                nitrogen hydride 17271
                                  azane 17007
                                    ammonia 17006
                                      organic amino compound 17005
                                        primary amino compound 7910
                                          primary amine 5699
                                            primary arylamine 2971
                                              aminobiphenyl 81
                                                biphenyl-4-amine 81
                                                  N-hydroxy-4-aminobiphenyl 5
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