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ONTOLOGY REPORT - ANNOTATIONS


Term:sphinganine
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Accession:CHEBI:16566 term browser browse the term
Definition:A 2-aminooctadecane-1,3-diol having (2S,3R)-configuration.
Synonyms:related_synonym: (2S,3R)-2-amino-1,3-octadecanediol;   (2S,3R)-2-aminooctadecane-1,3-diol;   (R-(R*,S*))-2-aminooctadecane-1,3-diol;   2-Amino-1,3-dihydroxyoctadecane;   C18-dihydrosphingosine;   C18-sphinganine;   D-erythro-1,3-dihydroxy-2-aminooctadecane;   D-erythro-2-amino-1,3-octadecanediol;   D-erythro-C18-dihydrosphingosine;   Dihydrosphingosine;   Formula=C18H39NO2;   InChI=1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1;   InChIKey=OTKJDMGTUTTYMP-ZWKOTPCHSA-N;   SMILES=CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO;   Safingol;   d18:0;   octadecasphinganine
 alt_id: CHEBI:15099;   CHEBI:26736;   CHEBI:26737;   CHEBI:549953;   CHEBI:9221
 xref: Beilstein:1724230 "Beilstein";   CAS:764-22-7 "ChemIDplus";   CAS:764-22-7 "KEGG COMPOUND";   HMDB:HMDB0000269;   KEGG:C00836;   KNApSAcK:C00007540;   LIPID_MAPS_instance:LMSP01020001 "LIPID MAPS";   MetaCyc:CPD-13612;   PMID:17085324 "Europe PMC";   PMID:1817037 "Europe PMC";   PMID:7654391 "Europe PMC";   PMID:7819132 "Europe PMC";   Reaxys:1724230 "Reaxys"
 cyclic_relationship: is_conjugate_base_of CHEBI:57817


show annotations for term's descendants       view all columns           Sort by:
 
1-O-(alpha-D-galactosyl)-N-hexacosanoylphytosphingosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6480464
N-acylsphinganine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
phytosphingosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
sphinganine 1-phosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Spns2 sphingolipid transporter 2 JBrowse link 10 59,010,428 59,049,482 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        inhibitor 18070
          enzyme inhibitor 17984
            EC 2.* (transferase) inhibitor 12155
              EC 2.7.* (P-containing group transferase) inhibitor 11807
                EC 2.7.11.* (protein-serine/threonine kinase) inhibitor 8104
                  EC 2.7.11.13 (protein kinase C) inhibitor 3351
                    sphinganine 13
                      1-deoxymethylsphinganine 0
                      1-deoxysphinganine + 0
                      3-dehydrosphinganine + 0
                      D-glucosylsphinganine 0
                      N-(2-hydroxytetracosanoyl)sphinganine + 0
                      N-acylsphinganine + 3
                      N-acylsphinganine-1-phosphocholine + 0
                      N-hexacosanoylsphinganine + 0
                      beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine + 0
                      hexosyl-(1<->1')-N-acylsphinganine + 0
                      inositol phosphomannosylinositol-1-phosphodihydroceramide + 0
                      phytosphingosine + 10
                      sphinganine 1-phosphate 2
                      sphinganine-1-phosphocholine 0
                      sphinganine-based sphingolipid + 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    main group molecular entity 19555
                      s-block molecular entity 19336
                        hydrogen molecular entity 19325
                          hydrides 18249
                            inorganic hydride 17113
                              pnictogen hydride 17071
                                nitrogen hydride 16891
                                  azane 16568
                                    ammonia 16565
                                      organic amino compound 16564
                                        amino alcohol 862
                                          aminodiol 151
                                            2-aminooctadecane-1,3-diol 13
                                              sphinganine 13
                                                1-deoxymethylsphinganine 0
                                                1-deoxysphinganine + 0
                                                3-dehydrosphinganine + 0
                                                D-glucosylsphinganine 0
                                                N-(2-hydroxytetracosanoyl)sphinganine + 0
                                                N-acylsphinganine + 3
                                                N-acylsphinganine-1-phosphocholine + 0
                                                N-hexacosanoylsphinganine + 0
                                                beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphinganine + 0
                                                hexosyl-(1<->1')-N-acylsphinganine + 0
                                                inositol phosphomannosylinositol-1-phosphodihydroceramide + 0
                                                phytosphingosine + 10
                                                sphinganine 1-phosphate 2
                                                sphinganine-1-phosphocholine 0
                                                sphinganine-based sphingolipid + 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.