Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

go back to main search page
Accession:CHEBI:16540 term browser browse the term
Definition:A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2.
Synonyms:related_synonym: 2-Pyridinol;   2-Pyridone;   2-hydroxypyridine;   Formula=C5H5NO;   InChI=1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7);   InChIKey=UBQKCCHYAOITMY-UHFFFAOYSA-N;   SMILES=Oc1ccccn1
 alt_id: CHEBI:11601;   CHEBI:1172;   CHEBI:19658
 xref: CAS:142-08-5;   HMDB:HMDB0013751;   KEGG:C02502;   KNApSAcK:C00007405
 xref_mesh: MESH:C017679
 xref: PMID:10952545;   Reaxys:105786

show annotations for term's descendants           Sort by:
pyridin-2-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
ISO 2-hydroxypyridine results in increased activity of CYP1A1 protein
2-hydroxypyridine results in increased expression of CYP1A1 mRNA
CTD PMID:11849738 PMID:12147272 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        biochemical role 19381
          metabolite 19356
            eukaryotic metabolite 19044
              plant metabolite 17455
                pyridin-2-ol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic heterocyclic compound 18582
                                  organic heteromonocyclic compound 17081
                                    pyridines 9096
                                      hydroxypyridine 81
                                        monohydroxypyridine 52
                                          pyridin-2-ol 1
paths to the root