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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-methyl-2-oxobutanoic acid
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Accession:CHEBI:16530 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is the 2-oxo derivative of isovaleric acid.
Synonyms:related_synonym: 2-Keto-3-methylbutyric acid;   2-Ketoisovaleric acid;   2-Ketovaline;   2-Oxo-3-methylbutanoic acid;   2-Oxo-3-methylbutyric acid;   2-Oxoisovaleric acid;   3-Methyl-2-oxobutanoate;   3-Methyl-2-oxobutyric acid;   Dimethylpyruvic acid;   Formula=C5H8O3;   InChI=1S/C5H8O3/c1-3(2)4(6)5(7)8/h3H,1-2H3,(H,7,8);   InChIKey=QHKABHOOEWYVLI-UHFFFAOYSA-N;   Isopropylglyoxylic acid;   SMILES=CC(C)C(=O)C(O)=O;   alpha-Ketovaline;   alpha-keto-isovaleric acid;   alpha-oxo-beta-methylbutyricacid;   alpha-oxoisovaleric acid
 alt_id: CHEBI:1584;   CHEBI:20115;   CHEBI:43714
 xref: CAS:759-05-7;   DrugBank:DB04074;   HMDB:HMDB0000019;   KEGG:C00141;   KNApSAcK:C00007623;   LIPID_MAPS_instance:LMFA01020274
 xref_mesh: MESH:C001505
 xref: MetaCyc:2-KETO-ISOVALERATE;   PDBeChem:KIV;   PMID:17190852;   PMID:192504;   PMID:7021997;   Reaxys:1744951
 cyclic_relationship: is_conjugate_acid_of CHEBI:11851;   is_tautomer_of CHEBI:132177



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3-methyl-2-oxobutanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance EXP LEPR affects the abundance of alpha-ketoisovalerate CTD PMID:20567778 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
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G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects abundance EXP SLCO1A4 protein affects the abundance of alpha-ketoisovalerate CTD PMID:21561886 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
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Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 22188
    role 22173
      biological role 22172
        biochemical role 21436
          metabolite 21384
            eukaryotic metabolite 21240
              fungal metabolite 18710
                Saccharomyces cerevisiae metabolite 18088
                  3-methyl-2-oxobutanoic acid 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    p-block element atom 22114
                      carbon group element atom 21915
                        carbon atom 21840
                          organic molecular entity 21840
                            organic group 20283
                              organic divalent group 20165
                                organodiyl group 20165
                                  carbonyl group 20159
                                    carbonyl compound 20159
                                      carboxylic acid 19557
                                        monocarboxylic acid 18919
                                          fatty acid 17128
                                            short-chain fatty acid 16341
                                              fatty acid 4:0 8386
                                                butyric acid 6802
                                                  3-methyl-2-oxobutanoic acid 2
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